LOCUS       c00014_gnlPro..        14698 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LCIAKKDL_14.
ACCESSION   c00014_gnlPro..
VERSION     c00014_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 12:10:53
            Original ID  :: gnl|Prokka|LCIAKKDL_14
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 21648
            Orig. end    :: 36346
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14698
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[31648:35162]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13514
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14698
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14698
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             1997..2389
                     /locus_tag="ctg14_19"
                     /transl_table=11
                     /translation="MDTLKLHSHFENLLYVGRSVLTNTSSRIQRLFFKKEMCIYEYLFK
                     EEASKGIEIVVDNAVLVCVFENDICNKSILYLNDSTNVTSYINYCNSTFEYDKLRDRWI
                     MPDGYLTLFMPNDDFEKRFAFVQTLV"
     CDS             2551..4398
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HMGL-like"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PYC_OADA"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg14_20"
                     /sec_met_domain="HMGL-like (E-value: 1.5e-18, bitscore:
                     58.2, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="PYC_OADA (E-value: 8.1e-19, bitscore:
                     59.0, seeds: 434, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKQTFIFVYVKLTKEKNHLLLAMMKKEIKFSLVYRDMWQSSGKY
                     QPRVDQLVRIAPLIVEMGCFTRVETNGGAFEQVNLLYGENPNKAVRAFTAPFREAGIQT
                     HMLDRGLNALRMYPVPADVRKLMYKVKHAQGVDITRIFCGLNETRNIIPSIKYALEAGM
                     IPQATLCITYSPVHTVEYYARIADQLIEAGAPEICLKDMAGIGRPGMLGQLVRTIKEKH
                     PDVLIQYHGHSGPGLSMASILEVCENGADIIDVAMEPMSWGKVHPDVISVQAMLKDLGF
                     QVPDINMKAYMKARAMTQEFIDDFLGYFMDPTNKYMSSLLLKCGLPGGMMGSMMADLKG
                     VHSGINMILRSKNEPELSLDDLLVMLFDEVEYVWPKLGYPPLVTPFSQYVKNVALMNLM
                     QLVKGEERWTMIDNHTWDMILGKSGRLPGTLAPEIIELAKSKGYEFVDTDPQLNYPDAL
                     DDYRKEMDENGWEHGEDDEELFELAMHDRQYRDYKSGVAKKRFEDELQHAKDASMAKSG
                     YSEEDIKKLKRAKADPVIAPDNGQVLWEVSVEGPSIAPFIGRKYQHDEVFCYLSTPWGE
                     YEKILTGFTGRVVEICAQQGATVRKGDVIGYILRSDIFA"
     CDS             4783..5271
                     /locus_tag="ctg14_21"
                     /transl_table=11
                     /translation="MGLEYVVTKRVFGFDKDKNEKYVAKSVRSGKVNFAKMCRKVSELC
                     GVHRKVVDLVVSGLVDKMAEDIDDGKSVQMGEFGIFTPTIRAKSTDDEKEVSSKSIVQR
                     KILFYPGKIFKNTLEDMSITRRAEIETDYTDGSSNGGNNGGNPDSGDDGKGEAPDPAA"
     CDS             5505..6782
                     /locus_tag="ctg14_22"
                     /transl_table=11
                     /translation="MKHGIFILAILMALLSLPESGYAAVPFFTVINDTIRRVVIYFDAN
                     ETNVNHCYRSNKEAIITLDSLLSGNSDTKYITALNVVSFVSPDGDESYNKSLVTKRNNS
                     IKEFLRRYELVNNVDKIHFCSKGEDWLEFRKLVASDTNLPDREEVLMLIDYHKDDIAKR
                     KQLLRKLNRGAAYRYMVRNVFPELRRSVITIVGETGIIDREAFEPVSSVSGLFVSNQEE
                     ALPKNQPDKPVGESEDKQTCEVDMSEAEEPVKSKTVLAVKNNLLYDLALAPNIEVEIPI
                     GKRWSLNTEYKCPWWLNSKHDFCYQLLSGGMEGRFWLGNRQKRDRLTGHFIGLYAEGGI
                     YDFQLRGDGYQGKYYGAAGVTYGYAKQLAQHFSLEFSLGIGYLTTEYKKYTPYEGDIVW
                     TNSGRYNFIGPTKAKVSLVWLITTKR"
     CDS             6810..7793
                     /locus_tag="ctg14_23"
                     /transl_table=11
                     /translation="MLLVLLSSLLVLNGCSRRDILDDYPVSGVEISLNWDGVTDKLPEG
                     IRVIFYPKDGEGKKVDRYLSVRGGEMKVPPGRYSVVAYNYNTESIRIRGEESYETIEAY
                     TGNCNGLGITGTEKMVWSPDSLYVLNIDELKIDKSEEVLSLDWKLESVVKKYSFAIEVK
                     GLEYVTAIVGCINGLSDCYHIGKGYGASSSQPIYFEVKKDGNKVVAYFTAFKQAKEMSV
                     PTRISESRSATSRGVGDIKLILRFIKTDNTVQEAAIDVTEIIETLEDTGTGDDGKQDPP
                     PEIELPSDDKIEVDKPELPPNPDGGGGMDGNVDGWGPEDNVELPVI"
     CDS             7849..8847
                     /locus_tag="ctg14_24"
                     /transl_table=11
                     /translation="MKKILLAVTAALAIMSCSQNEEFEAPNQQTKIDFTSVVRKATRAT
                     DTNSNNFLGFTVSSYITDGDYNGTDALGAAYMDGISYTKDNAAAPWTTTDKGTYYWPSI
                     SSGKKVQFFAYPTTDPTSYSLPDASYPTISFTVDGTPADQKDLVVAHATNVTSESSKVA
                     DGTLTLDFKHVLTRINFAFIPDDPLLTYAVTAVSIADVKGGTGKYSFNADNGEWNLAAA
                     ATSSYSYAVKQSADKVENKNYYSLADTNASWMLFPQEVNGKVISITYSTKQGAMEVFSG
                     TKKVTLPSDAKWTVGQNVLYVLTLPAGAAKVGLNTEVSEWNTADEKEETAK"
     CDS             9040..9879
                     /locus_tag="ctg14_25"
                     /transl_table=11
                     /translation="MPSICQGTWDCQICPKAVSNAITHVIYQRGFHKPAQRCEENFILF
                     LIKGEMLVNSKEYAGTMLKEGEFILQAIDSTFEMLAMLECECIYYRFIQPELFCDSRFN
                     HIMKDVSPPLIYSPIKIVPELQYFLQGSITYLKGNKVCRDLLSLKRKELAFVLGYYYSD
                     YDLSSLVHPLSKYINSFHYFVIQNYKKVKTVEELAQLGGYTLSTFRRIFNNVFHEPVYE
                     WMLARRKEGILDDLNNSAYSISEICYKYGFESLPHFSNFCKKSFGASPRNLRGQNRS"
     CDS             complement(10001..10756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_26"
                     /sec_met_domain="Fer4_7 (E-value: 2.1e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.5e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.4e-07, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFQDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(10793..12772)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 201.7; E-value:
                     7e-62)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_27"
                     /sec_met_domain="FAD_binding_2 (E-value: 3.3e-62, bitscore:
                     201.7, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 5.2e-37,
                     bitscore: 117.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLYTRYEMQDVVIVDGRARGIIAKNLVTGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAVKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDIVLQRYGNLFDMYEEITDVNPGE
                     LAKEINGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHVMWEYVGMGRTAEGLKKGIAELKEIRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLYKEPLVYEAIKVQTRNYKS"
     CDS             complement(12810..13514)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_28"
                     /sec_met_domain="SucD_FumR (E-value: 1.4e-131, bitscore:
                     426.9, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAGLAALFVIHIIYAFWLTMQNRKARGSERYAVTDKPKTVEWASQN
                     MLVLGLIVIVGLGLHLFNFWAKMQLPELMHNMGMHADTLTLAYAANGAYHIQQTFSCPV
                     YVVLYLVWLFALWFHLTHGFWSSMQSLGWNNKVWIDRWKCISNIYSTIVVLGFALVVVV
                     FFVKTLICGGAC"
     CDS             complement(13726..14595)
                     /locus_tag="ctg14_29"
                     /transl_table=11
                     /translation="MPGDSFCIQYTNCTGCPKNVENILVYRNLPKGEHIPKDKCTQNCM
                     LFMIKGELLINSEEHPGITLRERQIVLQAIGSKVEILALTDVEYVVYWFNELPLLCEER
                     YKEMMEQAEAPLTYTPLIMSERLYHLVTSMPEFLAEENPCSKYIDLKCKELVFLITNFY
                     PLPQLGSFFYPISTYTESFHYFVIQNYSNVKNVEEFAHLGGYTTTTFRRLFKNLYGMPV
                     YEWILEKKREGILEDLQHTKMRITEICNRYGFDSLSHFAHFCKDSFGDTPRALRKKAAS
                     GEKIGKVQ"
ORIGIN
        1 atatccatgc acatcgtgaa gcactggtca atgacctgcc tacggtaggt gttcttgctc
       61 atggtctgga tcgcatttat ccttatgtcc atcgaaaaac agccattgat atgctcgaaa
      121 aaggaggact attgactgaa tttctgtccg gtacgaatcc cgacaaacat aatttcgtca
      181 gtcgtaaccg tattgtcgca ggtatgtgtg atgctacagt tgtcattgaa tcggcagaaa
      241 aaggaggctc attaatcact gctgaacttg ctgaaagtta tcaccgtgat tgttttgctt
      301 ttcccggccg gataaatgat gaatattcaa agggatgtaa tcgattgatt agggataata
      361 aggcttcctt actattatcg gctgaagatc ttgtacaggc aatgggatgg aatataccgg
      421 caacttcttc cgagaaagta aatgtgcaac gtagtctttt tctcgacttg tccgaagaag
      481 aacagaagat tgtctctatc ctggagaaac aggggaattt acagattaat tctctggtag
      541 tagaagcaga tattcccgta cataaaataa atgctattct ttttgaactg gaaatgaaag
      601 gagtagttcg tgtattggca ggaggaatgt atcagttatt gaattaactc gtataaacta
      661 acctcatata tggatataaa aaaaggagca acgccttgct ccaacctttg ttaaccttaa
      721 atctaatact atgaaaaaaa tcacatgaca aatgtatgtc tttgcaaact aacctccaaa
      781 taattctgtt gtatttgttt ctcttttaaa ttctttcact gattttcact gttatcgtac
      841 acgatgcact cttaatggct aaagtagaat gcttttgggg taagtaatgg ggaggaaagt
      901 aagtcttcct gaatactatt gcagcttcta ggaaaattag aaaataaggt ctgaatataa
      961 gtgttttctt ggtttaaaag gaacgccccg ttggtttaaa accaaggcat cgttccttta
     1021 aaaccaatgg ggtgttcctt ttaaaggaaa gatattgctt tattttaagt gctttgcaat
     1081 aattttaatg tcaaatattg aaaaaataaa atgatagctt aattgattga aaatcagctt
     1141 tgtatggata aataatcctt tatattaacg gcaaaagccc aaaagacttg acaaacgctt
     1201 tttgatgttg tatatttgta taacgaaaga aacaatgaaa cgacaaatta aaactttaaa
     1261 aacgaaatga gacgaatctt atcttttgct gtattagctg cattgtactt ccccggatgt
     1321 acgaccagta aaaatgcagt gcgttgtcta agccgatgga ttaaagactg taacccgttg
     1381 accaaagaac ttgtaccgac cggttatatg ccgtataatc atcgttatct gacgatgaaa
     1441 cagtataaga ttataacaaa acatctagga gatccttatg aggattaggg tatagacgac
     1501 ccgataaaaa gcttgaggct gcaacctttt ataggatttg cagccttttt tgttgcataa
     1561 attcaatgta tacccttctg aaagctacat tcgggttttt aataaacttg gataccgttt
     1621 ctaataaact ccttgagaat ttattagaaa ctcaaaagtc gtttatacag aaaagataaa
     1681 cttttttcgg tgtactgaaa tgagaaannn nnnnnnngaa atatacgaaa tccttgtgtg
     1741 tttggttaat aatcactaca ttattaaaga cagtctcatt tcatctttat ttgtgtaacc
     1801 ttgaatgggt agatgtttct tcttgtaatt ctttatttta attgaaactt atcatacaat
     1861 catatatgat tgtgagtata tgaatgtgaa tatgttactt tggagaataa attatgtctg
     1921 gcaaatcaag aatcttaaat gagagagatc agtcataaaa tatttagcaa agtaataaca
     1981 ataaaaaaat gatgaaatgg atactcttaa attgcattca cactttgaaa atttgctgta
     2041 tgtgggaaga agcgtgctca ctaatacaag tagccgcatt caaagattgt tttttaaaaa
     2101 agagatgtgt atatatgaat acttgtttaa agaggaagca agtaaaggca ttgaaattgt
     2161 agtggacaat gctgtcttag tttgtgtttt tgaaaatgat atctgtaata aatctattct
     2221 ttatcttaat gactccacta atgtaacatc ttatattaat tattgcaata gtacttttga
     2281 atatgataaa cttcgtgata gatggattat gcctgatggt tatcttaccc tttttatgcc
     2341 gaatgatgac tttgaaaagc gatttgcatt cgtgcaaacc ttagtatgaa taaacttcgt
     2401 gaagcctttg gattcttaag gggatatatc tgaacattag acaatttgat ttgttattta
     2461 ttataattgg aagagtgtag gcattgtttg ctttcattat gatgtaaaac atctctattt
     2521 acccattttt taaaggctat ttttgactat atgtcaaaac aaacctttat atttgtatat
     2581 gtgaagttaa ccaaagaaaa aaatcactta ttattggcta tgatgaaaaa ggaaatcaaa
     2641 ttcagtcttg tttatcggga tatgtggcaa tcttccggta agtatcaacc tcgggttgac
     2701 cagcttgtac gtatagctcc attgattgtt gagatgggct gttttacaag agttgaaacg
     2761 aatggaggtg cttttgagca agtgaatcta ttgtacggcg aaaatcctaa taaagccgtc
     2821 cgtgctttta ccgcaccttt tagagaagcg ggcattcaaa cgcatatgct cgatcgtggt
     2881 ttgaatgcat tgcgtatgta tccggttccg gcagatgtgc gtaaattgat gtataaagtc
     2941 aagcatgcac aaggggtgga tatcacccgt atcttctgtg gactgaatga gacgagaaac
     3001 ataattccct ccattaaata tgctctggaa gcgggtatga ttccgcaggc gactctttgc
     3061 atcacatatt ctccggtgca taccgttgag tattatgccc gaattgccga tcaactgatt
     3121 gaggccggtg cacctgaaat atgtttgaaa gatatggcag gtatcggtcg cccgggtatg
     3181 ttggggcaat tggtcaggac tatcaaggaa aaacatccgg atgtattgat acaatatcat
     3241 ggtcatagcg gaccgggatt gtctatggca tctattctcg aggtttgcga gaatggtgcg
     3301 gatattattg atgtggctat ggagcccatg tcttggggta aagtgcatcc ggacgtgatc
     3361 tcggtacagg caatgttgaa agatttaggt tttcaggttc ccgatattaa tatgaaagca
     3421 tatatgaagg ctcgtgcgat gacgcaggaa ttcatagatg actttttggg ttacttcatg
     3481 gatcctacca acaaatatat gtcttcgctt ttattgaaat gtggtttgcc gggtggtatg
     3541 atgggttcta tgatggcaga tttgaaaggg gtacattccg gtatcaatat gatattacgg
     3601 agtaagaacg aacctgaact tagtcttgac gatttgctgg taatgctttt cgacgaagtg
     3661 gaatatgtgt ggcctaagtt gggttatcct cctttggtga ctcctttcag tcagtatgtg
     3721 aagaatgttg cattgatgaa tcttatgcaa ttggtaaaag gggaagagcg ctggacaatg
     3781 atagacaacc atacctggga tatgattctg ggtaagagtg gacgtctgcc gggtacgctt
     3841 gctccggaga ttatagaatt ggcgaagtct aaaggatatg agtttgtcga tactgatccg
     3901 cagttgaatt atccggatgc tttggatgat tatcgcaagg aaatggatga gaatggctgg
     3961 gagcatggag aggatgacga agaacttttt gaactggcta tgcacgatcg tcagtatcgc
     4021 gattataagt ccggtgttgc caagaaacgt tttgaggatg aattacaaca tgctaaggat
     4081 gcatccatgg caaagagtgg ttattccgag gaagatatca agaaattgaa acgtgccaag
     4141 gcggatccgg ttattgctcc cgacaacggg caggtacttt gggaagtttc cgtagaggga
     4201 ccatccattg cgccattcat cggacgtaaa tatcagcatg acgaagtctt ttgctacctt
     4261 tctactccat ggggagaata tgaaaagatt ctgaccggat ttaccggacg tgtggtggaa
     4321 atatgtgcac aacaaggcgc taccgtacgt aagggagatg ttatcggtta tattctgcgg
     4381 agcgatatct ttgcgtgaga tttctatgag agttagacta taggttactt tataaaaagg
     4441 tcaggctgca atctgtgatg aggttgcagc cttctttgtt tgtagacatt caatgtaaaa
     4501 gttacaggaa ggcttttagc tgttagaatt tcaatggcta tccattgata agttagagtg
     4561 ttgaacatgg aaaatacgca ttttatgaaa aaaataattc tttgatatat cctgttgata
     4621 actagcaata ttctcttccg ataataattg attccaaacg atgaaaggag acaaaagggg
     4681 accggacgtt ttacggttga tatacctttg cagagtcatt caaacaaaga gaatgacaaa
     4741 cagataacct ttattttttt aaccaattaa actttaacaa ttatgggttt agagtacgta
     4801 gtaacaaaaa gagtgttcgg ttttgacaag gacaaaaacg aaaagtatgt ggcaaaatcg
     4861 gttcgttccg gtaaggtgaa ttttgcaaag atgtgtcgga aagtaagtga gctttgtggt
     4921 gtccatcgta aggtggtaga tttggtcgtc agtggtctgg tggataagat ggcggaggat
     4981 attgatgatg gaaagagcgt gcagatgggt gagtttggta tcttcactcc tactatccgt
     5041 gctaagagta cggatgacga aaaggaggtc tcatccaagt cgatcgttca gagaaagatc
     5101 ttattctatc cgggaaaaat cttcaaaaat acgctggaag atatgagtat tacccgccgt
     5161 gcggaaattg aaacggatta tacggacgga agtagtaatg gggggaataa tgggggtaac
     5221 cctgattcgg gcgatgatgg caaaggggaa gcaccggacc cggctgcata attggactga
     5281 actttgtatt aaagcaagcc tttaattagt gaatgcacag agaatcgatc gatagattgg
     5341 ttatctgtgc attcttttta tatgattttc tgccttttat actcctcaaa cttgcaaaat
     5401 cgtttcaatc gtttcacaga acctttcagg gcctgtattt tctcctgaaa gtatgatttg
     5461 atttattttc taacttctat atttgtcaac agaaacgaac gacaatgaaa catggtatct
     5521 ttatcttggc tattcttatg gctttgttaa gccttccaga aagtgggtat gctgcggtac
     5581 cattttttac tgttattaat gatacaatcc gacgggtggt gatatatttc gatgcgaatg
     5641 aaacgaatgt gaatcattgt tataggagta ataaagaggc aattataaca ttagattcct
     5701 tgttgtccgg aaattcggat acgaaatata taacagcgtt aaatgtagtg agttttgttt
     5761 ctcctgatgg tgacgaatct tataataaaa gtttggttac taagagaaat aactcgataa
     5821 aggaattctt gaggcgatat gaattagtta ataatgttga taagattcat ttctgttcaa
     5881 agggagagga ttggttggag tttcgtaagt tggtggcatc tgacaccaac ttacccgacc
     5941 gggaagaagt gctgatgttg attgactatc ataaggatga tatcgccaaa agaaagcaac
     6001 tgttgcgtaa gctaaatcgg ggagccgcct accgatatat ggttcgtaat gtatttccgg
     6061 aattgaggcg gtctgttata acgattgtcg gagaaactgg gataatagat agagaggctt
     6121 ttgaaccggt atcttctgtc tccgggttgt ttgtttcgaa tcaggaagag gcgcttccga
     6181 agaatcaacc tgataagcct gtgggagaaa gtgaagataa acagacctgt gaggtcgata
     6241 tgtcggaggc agaagagccg gtgaaaagca aaacagtgct tgcagtaaag aacaatctat
     6301 tatatgattt ggcattggca ccgaatatag aagtagaaat tccgataggt aagaggtggt
     6361 ctttgaatac tgaatataaa tgtccgtggt ggttgaatag taaacacgat ttctgctatc
     6421 agctcctttc tggaggcatg gaaggacgtt tttggctggg aaaccggcag aagcgcgacc
     6481 gattgactgg acattttatt ggactttatg ctgaaggtgg aatatacgat ttccagttac
     6541 gtggagatgg gtatcagggt aagtactatg gagctgctgg agtgacttat ggatatgcaa
     6601 agcaattagc acagcacttt tcccttgaat tcagtcttgg catagggtat ttgacaacag
     6661 aatataagaa atatactcct tatgaggggg atattgtatg gacaaatagt gggcgttata
     6721 actttattgg tcctaccaaa gcaaaagttt ctttggtatg gttgataaca acaaagagat
     6781 aggagggcgt tatgcgaaat gcaagattca tgcttcttgt gcttctgtcc tcgctgctgg
     6841 tgctaaacgg gtgtagccgt cgcgatatat tggatgatta tcctgtaagt ggggtagaaa
     6901 tttcattaaa ctgggatgga gtaacagata aattaccaga aggtatccgg gttatatttt
     6961 atccgaaaga tggtgagggt aaaaaagtgg acaggtacct ttcggtacga ggtggagaaa
     7021 tgaaagttcc tccgggacga tattcggttg tagcttacaa ctataatacg gagtccatac
     7081 gtatccgagg agaagagtcc tatgaaacga tagaggctta tacaggaaac tgcaatggtt
     7141 tagggattac aggaacggaa aagatggttt ggtcaccgga ctcactgtat gtgctgaata
     7201 ttgatgaact gaaaatagat aagagtgaag aggtgctttc tttggattgg aaactggaat
     7261 cggtagtgaa gaagtattct tttgcgatag aggtcaaggg tttggagtac gtaacagcaa
     7321 tcgtagggtg tattaacgga ctatctgatt gttaccacat tggtaaaggt tatggagcat
     7381 cttcctcgca gcctatctat tttgaggtaa agaaagatgg taataaggta gtggcgtatt
     7441 tcacagcttt caagcaggca aaggaaatgt cagtcccgac acgaatatca gaatcaagga
     7501 gcgcaacttc ccgtggtgta ggcgatataa agttgatctt gagatttatc aaaacggata
     7561 atacggtgca agaagcagca attgatgtta ctgaaataat agagacactt gaagatactg
     7621 gaacaggaga tgatggaaaa caggaccctc caccggagat tgagttaccg tctgatgata
     7681 agattgaggt tgataagcca gagttaccgc cgaatcctga tgggggtgga ggaatggatg
     7741 gcaatgttga tgggtgggga ccggaagata atgttgaatt acctgtgatt taaaatagat
     7801 gttataaaca aaatagaaca atattataaa cttttaaaaa atacagttat gaagaaaatt
     7861 ttattggcag taacagctgc tttagcaatt atgagttgct cacaaaatga ggaatttgag
     7921 gcgccgaatc aacaaacaaa gattgatttt acttcagtag taaggaaagc tacaagagct
     7981 acagatacaa atagtaataa ctttttaggg ttcactgtaa gttcttatat tacagatggt
     8041 gactataatg gaacagatgc tttaggagct gcatacatgg atggaatctc atatacgaaa
     8101 gataatgctg ctgcaccttg gactactacc gataaaggaa cgtattattg gccatcaata
     8161 agttcaggaa aaaaagtaca attctttgca tacccaacga cagatcctac gtcctattct
     8221 cttcctgacg ctagctaccc tacaatatct ttcactgttg atggcactcc tgcggatcaa
     8281 aaagatttgg ttgttgcaca tgcaactaat gttacttcag agtcgagtaa agtagctgat
     8341 ggtacactga ccctagattt taaacatgtt ctaacccgta taaattttgc gtttattcct
     8401 gatgatcctt tgcttactta tgcagtgact gctgttagta tagctgatgt taaaggtgga
     8461 acaggtaaat atagttttaa tgcagataat ggtgaatgga atttggctgc tgctgctact
     8521 tcatcatata gttatgctgt taaacaatca gcagataagg ttgaaaataa gaattattat
     8581 tctttggctg atactaatgc atcttggatg ctatttcctc aagaagtaaa tggtaaggtt
     8641 atatcaataa catattcaac gaaacagggt gcgatggaag tcttttcagg aactaaaaaa
     8701 gtaactcttc ctagtgatgc caaatggaca gttggtcaaa atgtgctata tgtattaaca
     8761 ttacctgccg gtgctgctaa agttgggctt aatacagagg ttagcgaatg gaatactgca
     8821 gacgaaaaag aggagactgc taaatgataa aatggcactg tccatgattt agcataaatg
     8881 agaattattt ctaggttaag catattttaa atcctagctc ttcttttcga ggagctaggg
     8941 tttctttatt aacacagaac tttgtatgag atcttgtgag gttatttatc ttttatatgg
     9001 nnnnnnnnnn gcataaacaa atacaaacac agccagctta tgccatctat ttgtcaagga
     9061 acttgggatt gtcaaatatg tccgaaagca gtgagcaatg ctattactca tgttatttat
     9121 cagcgtggtt ttcataaacc agctcagagg tgtgaggaaa attttattct tttcttgatt
     9181 aaaggagaaa tgctggttaa tagtaaggaa tatgccggta ccatgctcaa agaaggtgaa
     9241 tttatacttc aagctattga ttctacattt gagatgcttg ccatgctcga atgtgagtgc
     9301 atctattacc gttttattca accggaattg ttttgtgatt ctcgtttcaa tcatataatg
     9361 aaagatgtat cgcctccact tatctattcc ccaataaaga tagttcctga actacaatat
     9421 tttttgcagg gttccatcac ttatttaaaa ggaaataaag tctgccggga tttgttgtct
     9481 ctcaagcgga aagagttggc atttgtgttg gggtattatt attctgatta tgacctctcg
     9541 agtctggtgc atccgctctc taagtacatc aatagtttcc actactttgt tattcaaaac
     9601 tataagaaag taaagactgt agaagaacta gcccaattag gaggatatac ccttagcaca
     9661 ttccgtcgta ttttcaataa tgtctttcat gaaccagttt atgaatggat gctggcacgc
     9721 cgtaaagagg gtattctcga tgacttgaat aattctgctt atagtatttc cgagatatgc
     9781 tataaatatg gttttgagtc cttaccccat ttctctaatt tctgtaagaa atctttcggc
     9841 gcttctccac gtaatttgcg tggacaaaac cgttcatgat aactgattat taataataat
     9901 catgatccat tcatatataa agaaatcccc tgtcggacta gccggcaggg gattctgtca
     9961 ttaatcaaat taagctctcg ctctcgaaat ctagcaattt ctagtctttt aattttgcga
    10021 tgatgaagtc acggttcaag cgggcgatgt tgctgataga gatgttcttc ggacattcag
    10081 cctcacaagc acgagtgttt gtacagttac cgaatcccag ttcatccatc tttgacaaca
    10141 tagcttttgc acgacgcaaa gcttccggtt taccttgcgg cagcaagttc aactggctaa
    10201 cttttgcaga aacgaacaac atagcagaac cattcttaca tgcagctaca caagcaccac
    10261 aaccgataca agaagcagca tccatagctt cgtcagcgat aggcttcgga atcaggatag
    10321 cgttagcatc ctgcggagca cctgtacgta cgctcacgta accaccagct tgcataatct
    10381 tgtcataagc agtacggtct accatcaagt ccttgattac agggaaaccg gccgaacgcc
    10441 aaggttcaac agtaatcgta tcaccatcct ggaaacgacg catatagatc tgacaagtag
    10501 tagcacctgt tgcaggaccg tgcgggtgtc cattgatgta aagagaacac ataccgcaga
    10561 taccttcgcg gcaatcgtgg tcgaatacta ccggttcttt tctttcgctg atgagctgtt
    10621 cgttcagaat atccagcatt tcgaggaagg aagtatcgcc ggggatatct ttcatttggt
    10681 aggtttcaaa agcaccttta gccttcggac cagcttggcg ccataccttc agtgtaaatg
    10741 atatattttt atccattttc ttctaattct tttaaatgtt taacttcacc gattagctct
    10801 tgtagttacg ggtttgaacc ttgatagctt cgtataccag cggttctttg tacaacaccg
    10861 gagctttttc atcgtcacct tgatattccc agcatgctac atagaagaag ttttcgtcat
    10921 cacgtttagc ttctccttct tcagtctggt attcttcacg gaagtgacca ccacaacttt
    10981 cgttacggtt caatgcatcg taagcaacaa gctcacccat tgtgatgaag tcgtacagac
    11041 ggattgcttt gtcaagctct acgttcatac cttctttaga accggggata aacagattcg
    11101 tttcgaattc cttgcggatt tctttcagtt cggcaatacc tttcttcaag ccttctgccg
    11161 tacgtcccat acctacatat tcccacataa catgacccag tttcttgtgg atagaatcaa
    11221 cagattcttt accctggatg ctcatgaact tgtcgatctt agcttgaact gccttttctg
    11281 cttcagcaaa ttcaggaaga tcagtagaga aacgaggaac agtgatttga tctgccagat
    11341 aattctggat tgtataaggc aatacgaagt aaccgtcagc caaaccttgc atcaatgcag
    11401 aagcaccgag gcggtttgca ccgtggtcgg agaagttaca ttcaccgata gcgaacagac
    11461 ccttgatagt ggtttgcagt tcgtagtcta cccagatacc acccattgta tagtggatag
    11521 ccggataaat catcatcgga ttataatatt ttacgccatt aatttctttt gccagttctc
    11581 ccggattaac gtcagtgatt tcttcataca tatcgaagag gttaccataa cgttggagaa
    11641 cgatgtcgat acccaagcgg ttgatagctt cagagaagtc aaggaatacg gctaaaccag
    11701 tgttgtttac accgaaacct gcgtcgcaac gttctttagc agcacggctg gcaacgtcac
    11761 gcggaaccag gttaccgaat gccggatagc ggcgttccaa gtaatagtcg cggtcttctt
    11821 caggaatatc acttcctttg atttcgcctt tttgaagttt cacagcatct tctttcttct
    11881 tcggaaccca gatacgaccg tcgttacgga gagattcaga catcaaagtc agtttagact
    11941 gcttgtcacc gtgtaccggg atacaagtcg ggtgaatctg aacgtaagca gggttagcga
    12001 atacagcacc cttgcggtag caagagatag cagctgtaca gttacatccc atagcgttgg
    12061 tagacaggaa gtaagcatta ccataaccac cggtagcgat aactacagcg tgagcggcaa
    12121 agcgttccag ttcacctgtt acaagatttt tagcgatgat accgcgagca cgtccgtcaa
    12181 cgatcaccac atcttgcatt tcataacgag tgtacagttt tacagtacct acgtttacct
    12241 gacggctcaa tgcagagtaa gcacccagca acaactgctg accggtctgg cctttagcgt
    12301 agaaagtacg ggatacctgt gcaccaccga aagaacggtt gtccagtgta ccaccatatt
    12361 cgcgagcgaa aggaacacct tgtgctacac attggtcgat gatagcgtta gacacttcag
    12421 ccagacgata tacgttagct tcacgggcac gatagtcacc accttttaca gtatcgtaga
    12481 acagacggta aacggagtca ccgtcatttt gataattctt tgcagcattg ataccaccct
    12541 gtgcagcgat agagtgtgca cgacggggag aatcctgaat acagaaattg aatactctga
    12601 aacccatttc accgagtgaa gcagcggcag aagcacctgc cagacccgta cccacaacga
    12661 tgatgtccaa acggcgttta ttagcggggt tcaccaattt ctggtgagct ttatagttgg
    12721 tccatttctc agccaccggg ccttctggaa tttttgaatc tatcttgatc ataatattat
    12781 ttacaattta atcatttaca atttactatt tagcaagcac caccacaaat aagtgttttc
    12841 acaaagaata ccactactac cagtgcgaaa ccgagtacaa cgattgtaga atagatgtta
    12901 gaaatacatt tccaacgatc aatccatact ttgttgttcc atcccagtga ttgcattgaa
    12961 ctccagaaac cgtgagtcag gtggaaccac aaagcaaaca gccaaacaag gtaaagaact
    13021 acgtaaaccg gacaagagaa agtctgctga atgtgatatg caccgttagc agcataagcc
    13081 aatgtcaatg tatcagcgtg catgcccatg ttgtgcatca gttccggcaa ctgcattttt
    13141 gcccagaagt tgaagaggtg caaaccaaga cctacgataa cgataagacc cagcaccaac
    13201 atgttttgag atgcccattc tacagttttc ggtttgtctg tcactgcata gcgttcgcta
    13261 ccacgcgctt tgcgattctg cattgtcagc cagaatgcgt agataatgtg aattacgaaa
    13321 agagcagcca gtcctgcggt agccactaat gcataccagt ttgctcccag gaactcacaa
    13381 atcatgttgt aaccatcagc cgagatgatc gcaaccaagt tcatcgccat gtgaaatgtt
    13441 agaaacagga caagggcgat accggtaacg ctcatcacca ctttccttcc tacagatgaa
    13501 ttacttaacc acataaatga ttgaatttaa attatttaat tgttagaact aaaatttcga
    13561 cgttttacac ctcttacgga ctgcaaaaat aggggaaata gattgattga gcaaggaatt
    13621 aaagaaataa ttccttaata atggatcaat acgccaatgt gtcaatatgc cagccagtat
    13681 atatgcatgg tgcaactgat tggcacattc gtaggatggg actgtttatt gtacctttcc
    13741 gattttctca ccgctggctg cttttttgcg taaagcgcgt ggggtatcgc cgaaagagtc
    13801 tttacagaag tgtgcgaaat gcgacaggga gtcgaatccg tatctgttac agatttcagt
    13861 gattcgcatt ttggtgtgtt gcaggtcttc caggattcct tcccgtttct tttccagtat
    13921 ccattcatat acgggcatac catataggtt tttgaaaagg cggcggaaag tagtggtcgt
    13981 gtatcctccc agatgtgcaa attcttctac gttcttcacg ttgctgtaat tctgtatgac
    14041 gaaatagtgg aaactttccg tataagtgct gattggatag aagaatgaac ctagctgggg
    14101 cagcggatag aagttggtaa tcaagaaaac cagttctttg cattttaaat cgatatactt
    14161 gctgcaaggg ttttcttcag cgaggaattc gggcatacta gtgacaaggt ggtaaagcct
    14221 ttcactcata atcagtggag tgtaggtcaa aggagcttcc gcctgttcca tcatttcctt
    14281 ataccgttct tcgcagagca aaggcagttc gttgaaccag tagacaacgt attcaacatc
    14341 tgtcagtgcc agtatttcga ctttggagcc aatagcttgc aaaacaattt gtctctcgcg
    14401 taacgttatt ccgggatgct cttcgctatt gataagtaat tcgcccttta tcataaaaag
    14461 catgcaattc tgcgtacact tatccttggg gatatgctct cctttaggta agtttctata
    14521 tacaaggata ttctcaacat tttttggaca tcctgtacag ttagtatatt gtatgcaaaa
    14581 tgaatctcct ggcatgagtc ttatgcgtga tttattatct taacggaaca aagataggct
    14641 ttttttgcgg aaaatggaac tctttcttct atttatgttt tggtagaagc ctttgtat
//
