LOCUS       c00076_gnlPro..        14157 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LCIAKKDL_79.
ACCESSION   c00076_gnlPro..
VERSION     c00076_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 12:10:53
            Original ID  :: gnl|Prokka|LCIAKKDL_79
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14157
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..570
                     /locus_tag="ctg76_1"
                     /transl_table=11
                     /translation="LEKRNFSENLLKTMNMMVEVDILLIKQIELKYLSKIKKLLYLLAV
                     DGPKAPNVSQLASDIQTSRATVMNYIKYLADARLINLVYPKGEEFPKKPSKIMMHNSNL
                     MYSIYPVKVEEQDVLDTFFVNSLWKDHKVHKGDKNVSFMVDEVMPFKICQEGAKIKNNP
                     NVTYALHKAEIGRGNQIPLWMFGFLY"
     protocluster    1..14157
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[602:4157](+)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      603..4157
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..14157
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14157
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             603..4157
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg76_2"
                     /sec_met_domain="PFOR_II (E-value: 6.1e-19, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 7e-83, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 7e-32, bitscore: 100.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.4e-12, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 2.4e-12, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 3.9e-09, bitscore: 26.0,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.9e-05, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.2e-25, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNPENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKVFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKTKQHLVDIKSNVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKLFNEILAADNASPEAKEVLKAWIENMYDADKTKE
                     LAPQVKAVIEEGLSHGCPICKELKGLTQYLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLW
                     RYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPTXXXXLKKTLNGVTT
                     ATNVWLEKTGVLNNSNTL"
     CDS             complement(4294..5160)
                     /locus_tag="ctg76_3"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAMLLLASCTNSDLEKKKVKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFFG
                     EVYGEARVGLVVPQYVTIHSINELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRLLVDSW
                     IPKSENK"
     CDS             complement(5181..5354)
                     /locus_tag="ctg76_4"
                     /transl_table=11
                     /translation="MVVIAAMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDR
                     ITQGMAGRKNKN"
     CDS             complement(5390..6010)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_5"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.6e-15, bitscore:
                     46.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMIHFSTFFDAVNAGIGSFIIGFQHILFGIP
                     FYITILVLAALAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSSRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASXXXXSELPVGSYCIKCSFLWRCPPF"
     CDS             complement(6007..7233)
                     /locus_tag="ctg76_6"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGNEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTTGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSKQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETREFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             complement(7533..7871)
                     /locus_tag="ctg76_7"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVSTYGGIAALLGMSQ
                     CSRMVGRALKQIPDDLSAPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVPE"
     CDS             7955..8266
                     /locus_tag="ctg76_8"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPIKSNPIINKTSTAVMKKKTILFASCLLGA
                     LAFSSCEKNLYDESKQPEKEKKMTDLEVPADFDXXXXQSENCQSINCYYFCISRRKLQ"
     CDS             8277..9242
                     /locus_tag="ctg76_9"
                     /transl_table=11
                     /translation="MLRMDVDANTSKLELPIEIPAYIKNVYVKYGNGSEIQTVPVESNG
                     TISIVVPANATALSRVTTRANKEVETNNIFNYPGYGNGTIMFEDMYPALGDYDFNDFVA
                     WYNFQIDGFYWSHNQCYAEYLMIGFQIRAIGGIYDYNPYIRLAEVQYNELDLEETQMYL
                     ERNNPEEAENIKILKGPKGELIISLKKPAIPNGYKYYNTEVNEKTKPKKMMAIYLVFNS
                     PVNVKSLQDSKMDFYIAKTNKGQEIHLKGYSPVYYNSNESYVNEDNFIWGLKVPASLHH
                     AREEVNFLEAYPDFEQWVTSGGQENQRWWNKPKTNKLIMN"
     CDS             complement(9382..12222)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 63; E-value: 1e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg76_10"
                     /sec_met_domain="Peripla_BP_1 (E-value: 1.8e-20, bitscore:
                     63.0, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAMKYTKWITVLFCLLGLAACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDKGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNYPDIKLIDKADAAWEREPAEVEMDSMLRRHPKIDAVYAHNDRI
                     APGAYQAAKKAGREKVMIFVGIDALPGKGNGLELVLDNVLDATFIYPTNGDKVMQLAMN
                     ILEKKSYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRSKNRLNKELSEQKKQVEQQRDKLEEQRDQLIQLSH
                     QLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADSSLSEDQRRMLLLVQRNVNILL
                     RLVNQILDFRKYENGKMEYTPISLDILSSFEGWNESFMAVARKKHIHFSFDYMPDTDYR
                     TLADVEKLERIYFNLLSNAFKFTPENGKVTVRLSSLTKDDHCWIRFTVANTGSMISAEH
                     IRNIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTITVESDEKQGTIFTVDLPVQTCET
                     VVSENSPAFSVSATSVTSTDATTSAVAGVPATPATSGYSGSSSLNDALTYEEEELEKSY
                     DSSKPCVLIIDDNADIRLYVHGLLHTDYTVIEAADGSEGIRKAMKYVPDLIISDVMMPG
                     MDGIECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYISKPFSSQLLLARVR
                     NLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGDSNLNVEDLGKDMGL
                     SRVQLYRKIKSLTNYSPNERLRIARLKKAASLLASSDMTVAEIGYEVGFSSPSYFTKCY
                     REQFGESPTDLLKRKG"
ORIGIN
        1 ctcgagaagc gtaacttctc ggagaatttg ctgaaaacga tgaacatgat ggtggaagta
       61 gatatacttc tcatcaaaca aattgaactg aaatatcttt caaagataaa aaaattacta
      121 tatttgctcg ctgtcgacgg gccgaaagct ccaaatgtga gccaactggc aagcgacata
      181 cagacatctc gcgccacggt gatgaactat atcaagtatc tggcagatgc gcgactcatt
      241 aatctggttt atccgaaagg ggaagaattc cctaaaaaac cttcgaagat aatgatgcac
      301 aactccaacc tgatgtattc catctacccg gtgaaagtgg aggagcagga tgtgctcgac
      361 actttctttg tgaattcttt atggaaagac cataaggtac ataaaggaga taaaaacgtc
      421 tcttttatgg tggacgaagt aatgccgttc aaaatttgcc aggaaggagc aaagatcaag
      481 aacaatccga atgtgacgta cgcgttgcat aaggctgaaa taggtcgggg caaccagata
      541 cctctctgga tgttcggctt tttatattaa aagatttatt tacttaaata tttaatttag
      601 ttatgactaa acagaagaaa ttcatcactt gtgatggtaa ccaggctgca gcgcatatct
      661 cgtatatgtt ctctgaagta gctgctatct accccatcac tccttcttcg actatggctg
      721 agtacgtaga cgaatgggct gccgcaggac gtaagaacat cttcggcgaa acagtattgg
      781 tacaggaaat gcaatctgaa ggtggtgctg ccggtgcagt tcacggttct cttcaggctg
      841 gtgcgttgac tactacttac actgcttctc agggtcttct cctgatgatc cctaacatgt
      901 acaaaattgc cggtgagttc ttgccttgcg tattccatgt atctgctcgt acattggctt
      961 ctcacgcatt gtgtatcttc ggtgaccacc aagacgtaat gtcagctcgt cagactggct
     1021 ttgcgatgtt ggctgaaggc tctgtacagg aagttatgga tttggctggt gttgctcact
     1081 tggctactat caaatctcgt gttccgttca tgaacttctt cgatggtttc cgtacatctc
     1141 acgaaatcca gaagattgaa atgttggaaa atgatgatct tgctccgctg attgatcagg
     1201 aagctttggc tgaattccgt gcccgcgcac tgaatccgat gaatccggtt gctcgtggta
     1261 tggctgaaaa tcctgaccat ttcttccaac atcgtgaatc atgcaacaac tactatgaag
     1321 cagttcctgc tatcgtagaa gaatacatga atgaaatttc taagattaca ggtcgtaaat
     1381 acggtttgtt cgattattat ggtgcagaag atgcagaacg cgtaattatc gctatgggtt
     1441 ctgtaacaga agctgcccgc gaagctatcg accacttggt agcaaatggc gaaaaagtgg
     1501 gtatggttgc cgtacacctg tatcgtccgt tctctgctaa acacttcctg gctgctgtac
     1561 ctaagactgc caagactatc gcagttcttg accgtactaa agaaccgggc gctaacggcg
     1621 aacctcttta ccttgacgtt aaagactgct tctacggcgc agaaaatgct ccggttatcg
     1681 ttggcggtcg ctacggtttg ggttcaaaag atactactcc tgctcaaatt ctttcagtat
     1741 tcgagaactt ggccatgcca atgccgaaga atcacttcac tatcggtatc gtagacgacg
     1801 ttactttcac ttctcttcct caaaaagaag aaatcgcttt aggcggtgaa ggaatgttcg
     1861 aagctaaatt ctacggtttg ggtgctgacg gtacagtagg tgctaacaag aactctgtaa
     1921 agattatcgg tgacaacact gacaaacact gccaggctta cttctcttat gactctaaga
     1981 agtcaggtgg tttcacttgt tctcacttgc gtttcggtga tactccgatc cgttccactt
     2041 atttggtaaa tactccgaac ttcgttgctt gtcacgttca ggcttacctg cacatgtacg
     2101 atgtaactcg tggtttgcgt aagaacggtt ctttcttgct gaacactatc tgggaaggtg
     2161 aagaactggc taagaacctg cctaacaagg ttaagaaata ttttgcacag aacaacattt
     2221 ccgtatacta tatcaacgca acacagattg cattggaaat tggtttgggt aatcgtacca
     2281 acactatcct tcaatctgca ttcttccgta tcacaggtgt tattcctgta gaccaggctg
     2341 ttgaacagat gaagaaattc atcgttaagt cttacggtaa gaagggtgaa gacgttgtta
     2401 acaagaacta tgctgccgtt gaccgtggtg gtgaatacaa gactttagct gttgatcctg
     2461 cttgggctaa cctgccggat gatgcaaaag ctgaaaacaa cgatcctgca ttcatcaacg
     2521 aagtagttcg tccgatcaat gcacaagatg gtgacttgct gcctgtatct gcattcaagg
     2581 gtatcgaaga cggtacttgg tatcaaggta cttctaaata cgaaaaacgt ggtgtagccg
     2641 cattcgttcc tgaatggaat ccagaaaact gtatccagtg taacaagtgt gcatacgttt
     2701 gtcctcacgc ttctatccgt ccgttcgtac tcgatgctga agagcagaag ggtgctaagt
     2761 tcgaacaatt gaaagcagta ggtaaagtat tcgacggtat gacattccgt atccaggttg
     2821 acgttctcga ctgtctgggt tgcggtaact gtgctgacat ctgtccgggt aatccgaaga
     2881 agggtggcaa agcattgaca atgaaacacc tcgaaagcca attggctgaa gctgacaact
     2941 ggacttactg tgctgaaaac gtgaagacta aacaacatct tgttgatatc aagtctaacg
     3001 tgaagaactc acagttcgct actccgttgt ttgagttctc tggtgcttgc tctggttgtg
     3061 gtgaaactcc gtatgtgaaa ttgatttctc aattgttcgg tgaccgtgaa atggttgcta
     3121 acgctaccgg atgttcttct atctactctg gttcagttcc ttctactccg tatactacga
     3181 acgaaaacgg tcacggtcct gcttgggcta actcactgtt cgaagacttc tgtgaattcg
     3241 gtttgggtat ggaattggct aacgaaaaga tgcgtgctcg tatcgtgaag ttattcaacg
     3301 aaatccttgc tgccgacaac gcttcacctg aagcaaaaga agtgctgaaa gcatggattg
     3361 aaaacatgta cgatgctgac aagactaaag aattggctcc ccaagtgaaa gcagtgattg
     3421 aagaaggtct ttctcacgga tgtcctattt gcaaagaact gaaaggactg actcaatatc
     3481 ttgtaaaacg cagccaatgg atcattggtg gtgacggtgc ttcttacgat atcggttatg
     3541 gtggtcttga ccatgtaatc gcttccggta aggacgttaa catcctcgtt ctggatactg
     3601 aagtttactc taacacaggt ggtcagtctt ctaaggctac tccggtaggt gctatcgcta
     3661 agttcgctgc tgctggtaag cgcgtacgta agaaagacct cggtctgatg gctactactt
     3721 acggttatgt atatgttgca cagatcgcta tgggtgctga ccaagctcaa actctgaaag
     3781 ctatccgtga agctgaagca tatccgggac catctttgat tatcgcttac gctccatgta
     3841 tcaaccacgg tctgaaagca ggtatgggta agagccagga agaagaagaa aaagctgtta
     3901 agtgcggtta ctggcacttg tggcgttaca acccagcttt ggaagaagaa ggcaagaacc
     3961 cattccaatt ggatagcaaa gaaccgaact gggaagattt ccaaggtttc ttgaagggtg
     4021 aagttcgtta cgcttctgta atgaaacaat atcctactgn nnnnnnnnng ctgaagaaaa
     4081 cgctaaatgg cgttacaaca gctacaaacg tttggctaga gaaaactggg gtgctgaata
     4141 atagtaatac cctataaata taaagcggta atcttatcaa agattaccgc ttttttattg
     4201 tatgaactct gtccaacata aacagtactc cctttttccc actagagttc atgtctattt
     4261 tatatttaaa attaagaata acaatgctcc aatctattta ttctctgact tcggaatcca
     4321 actatccacc aacagccgat gctcatccct ccatttacgg gctatttctt cttcatccat
     4381 cctggcatcc ttcatagctg tcataaaaga gctaagttct tctgtcgtta gtttgatgtt
     4441 gccaaagaat tcggcagcaa acggatcttt ctcactgaat cctttccatg caatagcatg
     4501 tatttcttcc aagtctccat atactttctt cggatcatcc aagaatttca agtcaaactg
     4561 gtcgaacatc caatgcggtg tccaccccgt aatgacaatc cattctcctt tgtccatcgc
     4621 ttttttcaaa gaagccagca tggtggaact acttgaagtc atgagggtat acccatcaag
     4681 tccgtaagca gcaatggcct tatcggtcgt cttcattatc cctgctcccg catcaattcc
     4741 tactatttca gaggaaaaac ggtctttatt agcttccagc tcattaatag agtggatcgt
     4801 aacatattga ggaacaacca gtccgacgcg agcttctccg tatacctccc caaaaaattc
     4861 gatgctgtct ccatactgat ccatataatc tttcatcgtt attggtaacc atgcatccag
     4921 aaacacatct gatttctttc ctgacataga tacaaaaata ggggcaagat cagcattttg
     4981 caattcaacc tcatatccat gctcttccaa taccacctta gccaaatgac tcatggcaat
     5041 accttccagc caattggcat aggctatttt tactttcttt ttctctaagt ctgaattagt
     5101 acaggaagct agcaaaagca tagctgacaa tactattcct actattttat atattctcat
     5161 acgtatttta tcctttccgt ttagttctta ttttttcgtc ctgccattcc ttgcgtgata
     5221 cggtctaaga tgatagctaa aataacaact gctataccac cttcaaaccc aagtccgatt
     5281 ttcatttggg taataccttt caatacaatt tctcccagac caccggcagc aatcatggca
     5341 gcaattacaa ccatagaaag cgacatcatt attgtctggt tgacaccagt cagaatggtg
     5401 ggcaacgcca aaggaagctg cactttatac aataactgcc aacgggtagc tccgaacnnn
     5461 nnnnnnggga agcttccact acatttttag gaacttgccg gattcccaat ccggtaaggc
     5521 ggaccacagg aggcatagca aagataatgg tggcaaacac tcctggcact gctcccaatc
     5581 cgaaaaacaa aacagcagga atcagataaa caaaagcagg catcgtctgc atcaagtcga
     5641 gaacaggacg gagtattttc tctgcacgcg aactgtttgc cgtccatact cctaaaggta
     5701 caccaacaat cagggccaga caggtagatg aaaaaacgag agctagagtt tgcatggtag
     5761 cctcccagaa tcccattcca tagatcagta ataatcccaa tgcggtgaaa attgccgtac
     5821 cgcgtcctgc tttcatccat gcgagtgcag caagtaccaa aatggttata taaaaaggta
     5881 ttccgaaaag tatgtgttgg aatcctataa taaaactacc gatgcccgca ttcacggcat
     5941 caaagaaagt ggaaaaatgt atcatcatcc aattgatggc catctctata tattgtccta
     6001 tatttatcat aaatctattg cgttttgaat tatttcgttt atttcttctt tatctttccc
     6061 ggtcacttcg atgattaagg atgaaagcgg gattgttcct aaaaactcgc gcgtctcatc
     6121 aatcacccat accggcgaat tgctctttgt cattagagga agtatatcct ccaacaccgt
     6181 atcctccaac acagaatgta cttctgtacg cacaatcgtt tcaatggatt tttcctgttt
     6241 gctacgtaac ttaagcaagt cgttcagacg tacttctccg accagtttat catcggcgtc
     6301 tatgacaggt aatacggtga tattcttcgc acgcatctta cgaatcaata cttcgggacc
     6361 ttctttcttc agacgggcca ccaacggttt gtcaatcatt aaagaagagg cggtaataat
     6421 tttgctccta tccacgtttt caacaaaacg ggctacataa tcgttagccg gttcagtcag
     6481 gatttcctcc gaagtaccta cctgcaccac ttctccgtct ttcatgatgg caatacggtc
     6541 acctagctta attgcttcac tcaagtcgtg ggtaataaaa acaatcgtct ttttcatctt
     6601 tgattgcaag gccagtagtt catcctgcat ctgtacgcga atcagaggat cgagagcaga
     6661 gaaagcctca tccattaaaa gcacttcagg attattagcc agagcgcgag ccagtccgac
     6721 acgctgttgc attccaccgg aaagctcgcc taccatctga ttttcatatc ctttcaatcc
     6781 gacaagcttc atgctttcca tcgctttctt ctcacgttcc tctttcttca ctccctgaag
     6841 ttcgaggccg aacgcgatat tgctcaatac ggaacggtga ggtaacagac cgaaattctg
     6901 gaaaaccatc gccagctctt tccgacgaac ctgcaataat tctttttcgg aaattttaga
     6961 tatatctact ccgtttacaa gcacttgccc ggtagtagga cgtatcagac gattgataca
     7021 acgcagtaat gtcgattttc cacttcccga gagtcccatt atcacgaaaa actctccttc
     7081 attaattgaa agattggcat ctttcactcc taccgtacaa ccggtatctt tcagaatttc
     7141 ctctttactc ttatcttttt tcaacatctt gagggctttc tgcttctcgt taccaaagat
     7201 aaggtacaaa tcctttattt ctattttact catataatat attggtttag attataatat
     7261 ttgttttgtt ttcaactgcc gcattcctta ttctcactta cgataaacaa gttgaatgtt
     7321 cgcatggttc agtcatgtca catgataaca tgacggtccg acgtttttta aatggttaaa
     7381 aaaaaacaga cagagtagtt taaaaggaat agaatttgat aagattatcc tcttaatgaa
     7441 cagtagaaaa cagtattttc ataaataaat aacagtctgt tcttgcatat tgttggcaca
     7501 aaggtaagga aaatagatta aatatgcaaa tttcattcag gtacggagta attccaaaga
     7561 tgctttttca agtctacgca tccattttgt ttgaaagaga tcccttcttc caacaagagt
     7621 tgtttctgct ctgtccaacc cggaacaagc cgtcccgacg cattgacaac ccgatgacaa
     7681 ggcgcagata aatcatccgg aatctgtttc aaagcacgcc ccaccatacg ggaacattga
     7741 gacattccca ataatgcggc aattccccca taggtagaaa ctttacctac cggaatttct
     7801 cggacaacct gatacacctc ttgacaaaag gatgcggaaa ggctcgcctt atctacttta
     7861 taatctttca tcactcaaac attactttat ttcagttcca aaactagata aaaagaaaag
     7921 aatttgcaaa taataaaagc atttcaaata aaatatgcaa ctttatttgc tttatttaca
     7981 aataatcccg acctttgtac ccattaaaag caaccctatt attaacaaaa caagcactgc
     8041 tgttatgaaa aagaaaacta tcctgttcgc ttcttgttta ttgggagcac tggctttcag
     8101 ctcctgtgag aagaaccttt atgatgaaag taaacaaccc gagaaagaaa agaagatgac
     8161 tgacttggaa gtacctgccg atttcgacnn nnnnnnnngc caaagtgaaa attgccagtc
     8221 aatcaactgc tactatttct gtatttctag aagaaaattg caatgaagag gctttgatgc
     8281 ttcgaatgga tgtcgatgcc aacacatcaa aattggaact cccaattgaa attcctgcat
     8341 atataaaaaa tgtgtatgta aaatatggta atggctctga aatacaaact gttcctgttg
     8401 aaagtaatgg tactatttct atagtagtac ctgctaacgc tacggcatta tccagagtta
     8461 ccacaagagc taataaagaa gttgaaacga acaacatctt caattatccg ggatatggca
     8521 acggaactat tatgttcgaa gatatgtatc cagctttagg cgattatgat tttaatgatt
     8581 ttgttgcatg gtataatttc caaattgacg gtttttattg gagtcacaat caatgttatg
     8641 cagaatactt aatgatagga ttccaaatca gagctatagg aggtatatat gactacaatc
     8701 cttatatccg cttggcagaa gtacaatata atgaacttga tttagaagaa actcaaatgt
     8761 atcttgagcg taacaatcct gaagaggctg aaaatatcaa aatcctaaaa ggcccaaaag
     8821 gggaattgat tatttcacta aagaaaccgg ccattcctaa cggatacaag tattataata
     8881 cggaggtaaa tgaaaaaaca aagcctaaaa aaatgatggc catttacttg gtgttcaact
     8941 cacctgttaa cgttaaaagc ctacaagaca gtaaaatgga cttttatatt gcaaaaacta
     9001 ataaaggaca agaaatccac ttaaaaggtt atagcccggt ttattataac agcaacgaaa
     9061 gttatgtaaa tgaagacaac tttatatggg gattaaaagt acctgcatct ttacatcatg
     9121 ccagagaaga agtaaacttc ttggaagcat atccagactt tgaacaatgg gtaacatcgg
     9181 gaggtcaaga gaaccaaaga tggtggaata agccaaaaac gaataagttg attatgaatt
     9241 aataaatata cagtaaatca tatactgaat taaataagag gtaaggtatg tcaatagatt
     9301 tccttacctc ttatttttat catatgaatt ctagaagtat aaacagataa atgctcacca
     9361 ccaaattttg cagattctat cctatccttt cctcttcaac aaatctgtcg gactctctcc
     9421 aaactgttct ctataacatt tagtaaaata agaaggagaa ctaaaaccaa cttcataacc
     9481 tatctctgcc actgtcatat ccgacgaagc aagcagggaa gcagctttct tcaaacgagc
     9541 tatacgaagc cgttcattcg gggaataatt agttagggat ttgattttgc gatagagttg
     9601 cacacggctt aatcccatat ctttacccaa gtcttccaca ttcaaatttg aatctcccat
     9661 ctttgcctca atcaaagctt tgaatttttc cacaaagtct ttatccatat cacagacatc
     9721 ctctttcgcc aacgtttgtc cgtcaccaaa aaactgtttc aggcggcggt gtgaatctat
     9781 cagattacga acgcgtgcca atagtaattg cgaactgaaa ggcttggaga tataagaatc
     9841 tgcaccacca tcataccctt gaattcgttg ttcatccaaa gaacaagctg tcaataggat
     9901 aacaggaata tgacaggttt gtaattcgct tttcaagcga cgacaacatt caattccatc
     9961 cattccgggc atcattacat cggagataat caagtccggg acatatttca tagctttacg
    10021 aataccttcc gagccgtctg cagcttctat aacagtataa tcagtatgaa gcaatccatg
    10081 cacatataag cgaatatcag cgttatcatc aataatcaga acgcaaggtt tggaagagtc
    10141 gtaacttttt tccaattcct cttcttcgta agttaaagca tcattcaagc tcgaagaacc
    10201 ggaataaccg gaagttgcag gagttgccgg aaccccagca acggcagagg ttgtagcatc
    10261 ggtggaggtt acagaagtag cagacacaga gaatgccgga gagttttcag aaacaacagt
    10321 ctcgcaagtc tgcacaggca aatcaacggt aaagatagtt ccttgctttt catcactttc
    10381 caccgtgatg gtacctttat gcaattccac aaaagccttt accaatgcca gtccaatacc
    10441 cgaaccggca tggtgcatat ctatcttata gaaacggtcg aaaatattcc ggatatgctc
    10501 cgcagaaatc attgaaccgg tattggcaac ggtaaagcga atccagcaat gatcgtcttt
    10561 agtcagggaa gacaagcgta cagttacttt tccgttttcc ggagtaaatt tgaaagcgtt
    10621 ggaaaggagg ttgaaataga tgcgttccaa cttttctaca tctgccaatg tgcggtaatc
    10681 cgtatccggc atataatcga atgagaaatg aatatgcttc ttccgggcta ctgccatgaa
    10741 agattcgttc catccttcaa aagaagaaag aatgtctaac gaaataggag tatattccat
    10801 ttttccattc tcgtatttac gaaaatccag aatctgattg acaagacgca aaaggatatt
    10861 cacgtttcgc tgaactaaca ataacattcg gcgctgatct tcactcaaag acgaatcagc
    10921 cagtaaatgc tctaccgggt cggcaactaa tgtcagtgga gtacgaaaat cgtgagatat
    10981 atttgtgaag aaaaccagct tggcatgagt cgcttcttcc agttgatgag aaagctggat
    11041 aagctgatcc cgttgctctt cgagtttatc gcgctgttgc tctacttgtt tcttctgttc
    11101 ggacaactct ttattcaggc gattcttgga acggagggat ttatagacta ccaacaacaa
    11161 tcccgctact aataaaagaa taaccaagcc gccatacatc acgacctgct gcgtagctac
    11221 acgcgacaga tacccaccga tacgtccgtt caatgtttca atcttctgat ccagttccga
    11281 gatatgggta gtctgaagtt gcataacgtg cgcgttcgtg cggtctacaa cggcagtatt
    11341 catgaccgtt tcgcgaggat aagacttctt ctcaagaata ttcatggcca gttgcatcac
    11401 tttgtcccca ttagtcggat aaataaaagt tgcatccagc acattgtcaa gcaccaattc
    11461 aagcccgttt cctttgccgg gcagggcatc aatgccaaca aaaatcatta ccttttcacg
    11521 tccggctttc ttcgcagctt gataggctcc cggagcgata cggtcgttat gtgcatatac
    11581 cgcatcaatc ttcggatgac ggcgaagcat actatccatt tccacttctg ccggttcacg
    11641 ttcccaggca gcatccgctt tatcaatcag tttgatatcc ggataattgc tgatagcagc
    11701 cataaatccc tgatggcgtt ccatggcagg ggtggaacca cccagtccgg taagctccac
    11761 tacattccct ttccctttca gacttgatgc gatataattt cctaccgcac gacctatttc
    11821 ataattatcg gcaccgatat aggcagtata tttatcagaa agtatcttcc ggtctacaag
    11881 aatgacaggt attcctttct gataggcctc ctccacaatt ggagtcatgg gagccgcttc
    11941 attggcggaa attatcagta aatcaactcc tttatctata aaataatgaa catcttccgc
    12001 ctgcttacgg ttatcatccg ccgccgagcg gatttcaacc gacactccat cataaaacat
    12061 cgcttcgcga agaatctcat cattcatctt gtgcctccaa gagtcatcgc tacattgggc
    12121 caccccaata cggaaacgag gcgcatcctg ccgacaggcc gccaagccca aaagacaaaa
    12181 caagactgtt atccacttcg tatatttcat cgcttcaatc attccctttc tttcgtatat
    12241 cttttgtatt tctttctgta atccaaattt ctccccccgc attatttgca ttcaccaccg
    12301 ggaaatacat cagttccact ttcacagggt tcagcgtata ttttccagta aagcgtggaa
    12361 gcaaaggaac cgtaaactga taagtaccta ccnnnnnnnn nncaggtttt gaggcataac
    12421 tacaacctcc cggaacagga acttcgagca tcacatattg cgcaccctcc tgtttcacct
    12481 gcaaggtaac tgtcaatgta acaggtacac ccgccaccaa agagtctttt tccaaagtca
    12541 cctccacctt gaaagcatca ctctgacgag cattcatcac acgcttcatt gaatagacac
    12601 tatacaataa aggctctttt cccgtttttg aaataagcag actgtcgctt gctgtcagcc
    12661 gggcatgata aggaaattcc gtaattcgtt gatgatcctt accgctcaca gacaccgacg
    12721 ttcctgacat ccctccggaa cctgccagca aatcggtcag aacagttgcc acagccgaag
    12781 aagcctgata cgtattccat ccgcgctcct tagtccgcaa aatatacaat tgcatatttt
    12841 ctttcaactt acacagggaa gggtcatttt taataatccg gtaggctatc aatgtattta
    12901 tcatctgatt tccctcccaa taataagtac gccgtccgtc gtcacagtaa acaccttcca
    12961 gcatatcctt tttcagataa ggacgtacgc tatcacccac attcaccgaa tccacctgtt
    13021 gcttgatttc ccagagaagc agcttctctt tcaagtatga aagaggacga taatacttgt
    13081 ttctatttgc caacgagtct tctttctgtt ccaattgccg gacgaaaggt tccaataatc
    13141 tgactgccga agaataatcc gcctctactt tccactcatg cagagcatga agtatttcta
    13201 tatcttccag tttcattcct cgataaggac gcgtatgagc atactccact ttcaaaccat
    13261 tcagattcaa ctccacagga taacctgcat cttgcgccat cttcaaagcc cgcagaatct
    13321 gcgcagacat ccagaaagaa gtattttcag agttccccca ccacgaccat aactgatgtt
    13381 tgttctgatg attcgtcagt cgatggatga taggtcgaat tgctttatct actttcacct
    13441 tttcaccctt actctgcata tactgttggt aagccaacaa accgattaac ttggatgcca
    13501 gctgctcatt gcacaaatat ttgtatcctg tcaagtaatt cactgattct ttatagatgt
    13561 ccaactgatt gtcagtgata ctcaccatca cttcttcatc ctcgccggat tgcactttaa
    13621 ccgtctttgc atcggacaga atacccaatg tgccctccgc caattcagtt ccctgtgcca
    13681 gtatcggaat cgtatattcc tctccatcct gatagccatc gtcgcgagtg aaaagatagc
    13741 tgatggtcac gctatcggca tgaactgcct gcatcggcac tgtttcatga aatccctcca
    13801 tgaaactcac ttcctgccgt ttcaacgtat ccgttccgac gcagaactgt gtctttccgg
    13861 ctatgtgctg cccatccaga taattgcgga tagtcccgac caccgtactc tgatccccct
    13921 ccaccaagaa gcggggagtt ttcaactccg ccatcaacgg tttgtaagag cggacgaaac
    13981 gtcggaaagt acccgtctgc aaacgacggt tcatgccata aacgacagtt tcccatttcg
    14041 tcacattatc ggggaaagtt gtttcaaact gtaccgttcc ggttttatcc gtaaacaaac
    14101 gaggctgcca gaaagccaca tccgaaaaat tcctacgtaa gccattcaat tgcatca
//
