LOCUS       c00002_gnlPro..        16373 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MHFLJGAK_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:38:30
            Original ID  :: gnl|Prokka|MHFLJGAK_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 201220
            Orig. end    :: 217593
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16373
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[211220:214772](-)"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      complement(10001..13552)
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /neighbourhood="10000"
                     /product="PFOR_II_pathway"
                     /protocluster_number="1"
     cand_cluster    1..16373
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds(POR and POR_N and PFOR_II and EKR and
                     Fer4_16 and TPP_enzyme_C)"
                     /kind="single"
                     /product="PFOR_II_pathway"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16373
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="PFOR_II_pathway"
                     /region_number="1"
                     /rules="cds(POR and POR_N and PFOR_II and EKR and Fer4_16
                     and TPP_enzyme_C)"
                     /tool="gutsmash"
     CDS             1917..4757
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1042:Periplasmic binding proteins and sugar binding
                     domain of LacI family (Score: 63; E-value: 1e-19)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_137"
                     /sec_met_domain="Peripla_BP_1 (E-value: 2.3e-19, bitscore:
                     63.0, seeds: 6, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEAMKYTKWITVLFCLLGLAACRQDAPRFRIGVAQCSDDSWRHK
                     MNDEILREAMFYDGVSVEIRSAADDNRKQAEDVHYFIDKGVDLLIISANEAAPMTPIVE
                     EAYQKGIPVILVDRKILSDKYTAYIGADNYEIGRAVGNYIASSLKGKGNVVELTGLGGS
                     TPAMERHQGFMAAISNYPDIKLIDKADAAWEREPAEVEMDSMLRRHPKIDAVYAHNDRI
                     APGAYQAAKKAGREKVMIFVGIDALPGKGNGLELVLDNVLDATFIYPTNGDKVMQLAMN
                     ILEKKSYPRETVMNTAVVDRTNAHVMQLQTTHISELDQKIETLNGRIGGYLSRVATQQV
                     VMYGGLVILLLVAGLLLVVYKSLRSKNRLNKELSEQKKQVEQQRDKLEEQRDQLIQLSH
                     QLEEATHAKLVFFTNISHDFRTPLTLVADPVEHLLADSSLSEDQRRMLLLVQRNVNILL
                     RLVNQILDFRKYENGKMEYTPISLDILSSFEGWNESFMAVARKKHIHFSFDYMPDTDYR
                     TLADVEKLERIYFNLLSNAFKFTPENGKVTVRLSSLTKDDHCWIRFTVANTGSMISAEH
                     IRNIFDRFYKIDMHHAGSGIGLALVKAFVELHKGTITVESDEKQGTIFTVDLPVQTCET
                     VVSENSPAFSVSATSVTSTDATTSAVAGVPATPATSGYSGSSSLNDALTYEEEELEKSY
                     DSSKPCVLIIDDNADIRLYVHGLLHTDYTVIEAADGSEGIRKAMKYVPDLIISDVMMPG
                     MDGIECCRRLKSELQTCHIPVILLTACSLDEQRIQGYDGGADSYISKPFSSQLLLARVR
                     NLIDSHRRLKQFFGDGQTLAKEDVCDMDKDFVEKFKALIEAKMGDSNLNVEDLGKDMGL
                     SRVQLYRKIKSLTNYSPNELLRIARLKKAASLLASSDMTVAEIGYEVGFSSPSYFTKCY
                     REQFGESPTDLLKRKG"
     CDS             complement(4897..6192)
                     /locus_tag="ctg2_138"
                     /transl_table=11
                     /translation="MQLYLLYLQIIPTFVPIKSNPIINKTSTAVMKKKTILFASCLLGA
                     LAFSSCEKNLYDESKQPEKEKKMTDLEVPADFDWKGSQNAKVKIASQSTATISVFLEEN
                     CNEEALMLRMDVDANTSKLELPIEIPAYIKNVYVKYGNGSEIQTVPVESNGTISIVVPA
                     NATALSRVTTRANKEVETNNIFNYPGYGNGTIMFEDMYPALGDYDFNDFVAWYNFQIDG
                     FYWSHNQCYAEYLMIGFQIRAIGGIYDYNPYIRLAEVQYNELDLEETQMYLERNNPEEA
                     ENIKILKGPKGELIISLKKPAIPNGYKYYNTEVNEKTKPKKMMAIYLVFNSPVNVKSLQ
                     DSKMDFYIAKTNKGQEIHLKGYSPVYYNSNESYVNEDNFIWGLKVPASLHHAREEVNFL
                     EAYPDFEQWVTSGGQENQRWWNKPKTNKLIMN"
     CDS             6276..6614
                     /locus_tag="ctg2_139"
                     /transl_table=11
                     /translation="MKDYKVDKASLSASFCQEVYQVVREIPVGKVSTYGGIAALLGMSQ
                     CSRMVGRALKQIPDDLSAPCHRVVNASGRLVPGWTEQKQLLLEEGISFKQNGCVDLKKH
                     LWNYSVPE"
     CDS             6914..8140
                     /locus_tag="ctg2_140"
                     /transl_table=11
                     /translation="MSKIEIKDLYLIFGNEKQKALKMLKKDKSKEEILKDTGCTVGVKD
                     ANLSINEGEFFVIMGLSGSGKSTLLRCINRLIRPTTGQVLVNGVDISKISEKELLQVRR
                     KELAMVFQNFGLLPHRSVLSNIAFGLELQGVKKEEREKKAMESMKLVGLKGYENQMVGE
                     LSGGMQQRVGLARALANNPEVLLMDEAFSALDPLIRVQMQDELLALQSKMKKTIVFITH
                     DLSEAIKLGDRIAIMKDGEVVQVGTSEEILTEPANDYVARFVENVDRSKIITASSLMID
                     KPLVARLKKEGPEVLIRKMRAKNITVLPVIDADDKLVGEVRLNDLLKLRSKQEKSIETI
                     VRTEVHSVLEDTVLEDILPLMTKSNSPVWVIDETREFLGTIPLSSLIIEVTGKDKEEIN
                     EIIQNAIDL"
     CDS             8137..8961
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) BPD_transp_1"
                     /gene_functions="transport (smcogs)
                     SMCOG1004:Binding-protein-dependent transport system inner
                     membrane component (Score: 92.9; E-value: 6.9e-29)"
                     /gene_kind="transport"
                     /locus_tag="ctg2_141"
                     /sec_met_domain="BPD_transp_1 (E-value: 1.6e-28, bitscore:
                     92.9, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINIGQYIEMAINWMMIHFSTFFDAVNAGIGSFIIGFQHILFGIP
                     FYITILVLAALAWMKAGRGTAIFTALGLLLIYGMGFWEATMQTLALVFSSTCLALIVGV
                     PLGVWTANSSRAEKILRPVLDLMQTMPAFVYLIPAVLFFGLGAVPGVFATIIFAMPPVV
                     RLTGLGIRQVPKNVVEASRSFGATRWQLLYKVQLPLALPTILTGVNQTIMMSLSMVVIA
                     AMIAAGGLGEIVLKGITQMKIGLGFEGGIAVVILAIILDRITQGMAGRKNKN"
     CDS             8982..9848
                     /locus_tag="ctg2_142"
                     /transl_table=11
                     /translation="MRIYKIVGIVLSAMLLLASCTNSDLEKKKVKIAYANWLEGIAMSH
                     LAKVVLEEHGYEVELQNADLAPIFVSMSGKKSDVFLDAWLPITMKDYMDQYGDSIEFFG
                     EVYGEARVGLVVPQYVTIHSINELEANKDRFSSEIVGIDAGAGIMKTTDKAIAAYGLDG
                     YTLMTSSSSTMLASLKKAMDKGEWIVITGWTPHWMFDQFDLKFLDDPKKVYGDLEEIHA
                     IAWKGFSEKDPFAAEFFGNIKLTTEELSSFMTAMKDARMDEEEIARKWRDEHRLLVDSW
                     IPKSENK"
     CDS             complement(10001..13552)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: EKR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: Fer4_16"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: PFOR_II"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     PFOR_II_pathway: POR"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_6"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_143"
                     /sec_met_domain="PFOR_II (E-value: 8e-18, bitscore: 57.9,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 9.3e-82, bitscore: 267.4,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 9.3e-31, bitscore: 100.4,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.9e-11, bitscore:
                     37.2, seeds: 323, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_16 (E-value: 3.2e-11, bitscore: 37.3,
                     seeds: 227, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_6 (E-value: 5.1e-08, bitscore: 26.0,
                     seeds: 134, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00026, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="EKR (E-value: 1.6e-24, bitscore: 78.8,
                     seeds: 127, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKQKKFITCDGNQAAAHISYMFSEVAAIYPITPSSTMAEYVDEW
                     AAAGRKNIFGETVLVQEMQSEGGAAGAVHGSLQAGALTTTYTASQGLLLMIPNMYKIAG
                     EFLPCVFHVSARTLASHALCIFGDHQDVMSARQTGFAMLAEGSVQEVMDLAGVAHLATI
                     KSRVPFMNFFDGFRTSHEIQKIEMLENDDLAPLIDQEALAEFRARALNPMNPVARGMAE
                     NPDHFFQHRESCNNYYEAVPAIVEEYMNEISKITGRKYGLFDYYGAEDAERVIIAMGSV
                     TEAAREAIDHLVANGEKVGMVAVHLYRPFSAKHFLAAVPKTAKTIAVLDRTKEPGANGE
                     PLYLDVKDCFYGAENAPVIVGGRYGLGSKDTTPAQILSVFENLAMPMPKNHFTIGIVDD
                     VTFTSLPQKEEIALGGEGMFEAKFYGLGADGTVGANKNSVKIIGDNTDKHCQAYFSYDS
                     KKSGGFTCSHLRFGDTPIRSTYLVNTPNFVACHVQAYLHMYDVTRGLRKNGSFLLNTIW
                     EGEELAKNLPNKVKKYFAQNNISVYYINATQIALEIGLGNRTNTILQSAFFRITGVIPV
                     DQAVEQMKKFIVKSYGKKGEDVVNKNYAAVDRGGEYKTLAVDPAWANLPDDAKAENNDP
                     AFINEVVRPINAQDGDLLPVSAFKGIEDGTWYQGTSKYEKRGVAAFVPEWNPENCIQCN
                     KCAYVCPHASIRPFVLDAEEQKGAKFEQLKAVGKVFDGMTFRIQVDVLDCLGCGNCADI
                     CPGNPKKGGKALTMKHLESQLAEADNWTYCAENVKTKQHLVDIKSNVKNSQFATPLFEF
                     SGACSGCGETPYVKLISQLFGDREMVANATGCSSIYSGSVPSTPYTTNENGHGPAWANS
                     LFEDFCEFGLGMELANEKMRARIVKLFNEILAADNASPEAKEVLKAWIENMYDADKTKE
                     LAPQVKAVIEEGLSHGCPICKELKGLTQYLVKRSQWIIGGDGASYDIGYGGLDHVIASG
                     KDVNILVLDTEVYSNTGGQSSKATPVGAIAKFAAAGKRVRKKDLGLMATTYGYVYVAQI
                     AMGADQAQTLKAIREAEAYPGPSLIIAYAPCINHGLKAGMGKSQEEEEKAVKCGYWHLW
                     RYNPALEEEGKNPFQLDSKEPNWEDFQGFLKGEVRYASVMKQYPTEAEELFKAAEENAK
                     WRYNSYKRLARENWGAE"
     CDS             complement(13585..14763)
                     /locus_tag="ctg2_144"
                     /transl_table=11
                     /translation="MESFYRTHAYLVEHTNAPVRRDLMDEIDWSDRLIGIKGTRGVGKT
                     TFLLQYAKEKFGNDRSCLFINMNNFYFSGHSIVDFANEFQKRGGKVLLIDQVFKHPEWS
                     KELRMCYDRFPNLKIVFTGSSVMRLKEENLELRDIAKSYNLRGFSFREYLNLQTGMKFR
                     AYSLEEILSTHEQIAKGVLSKVRPLDYFQDYLHHGFYPFFLEKRNFSENLLKTMNMMVE
                     VDILLIKQIELKYLSKIKKLLYLLAVDGPKAPNVSQLASDIQTSRATVMNYIKYLADAR
                     LINLVYPKGEEFPKKPSKIMMHNSNLMYSIYPVKVEEQDVLDTFFVNSLWKDHKVHKGD
                     KNVSFMVDEVMPFKICQEGAKIKNNPNVTYALHKAEIGRGNQIPLWMFGFLY"
     CDS             14911..16125
                     /locus_tag="ctg2_145"
                     /transl_table=11
                     /translation="LNSFKMTKKALYIFNPEHDLALASGETNYMAPASARQMASELALL
                     PMWYAEEGSVVLAPSAYNLDYVKKIQELLGLSVDLMTEPELASERNLDIRPWGWDIAIR
                     KRLLDLGVEESELPSIEQLDKLRFCSHRSCAVGLLPQLQLGACFCGESFYLTFPEEWKS
                     FVESHDTCLLKAPLSGSGKGLNWCKGVYTPSISGWCSRIGKQQGGVIGEPLYNKVEDFA
                     MEFRSSSNGRFGFAGYSQFRTGGSGAYEGNLLISDAAIERNLLEYIPVEEIYKLRDRLE
                     QELSLRFGTIYNGYLGVDMMICRFPESPVYRIHPCVEINLRMNMGVVARHIYDHYIYPT
                     STGAFQISYYPTEGTAWRAHKEMEEAYPLEIEQGRIKSGYLSLVPAHKKSSYRAWVFIS
                     KSVFL"
ORIGIN
        1 ggtacagttt gaaacaactt tccccgataa tgtgacgaaa tgggaaactg tcgtttatgg
       61 catgaaccgt cgtttgcaga cgggtacttt ccgacgtttc gtccgctctt acaaaccgtt
      121 gatggcggag ttgaaaactc cccgcttctt ggtggagggg gatcagagta cggtggtcgg
      181 gactatccgc aattatctgg atgggcagca catagccgga aagacacagt tctgcgtcgg
      241 aacggatacg ttgaaacggc aggaagtgag tttcatggag ggatttcatg aaacagtgcc
      301 gatgcaggca gttcatgccg atagcgtgac catcagctat cttttcactc gcgacgatgg
      361 ctatcaggat ggagaggaat atacgattcc gatactggca cagggaactg aattggcgga
      421 gggcacattg ggtattctgt ccgatgcaaa gacggttaaa gtgcaatccg gcgaggatga
      481 agaagtgatg gtgagtatca ctgacaatca gttggacatc tataaagaat cagtgaatta
      541 cttgacagga tacaaatatt tgtgcaatga gcagctggca tccaagttaa tcggtttgtt
      601 ggcttaccaa cagtatatgc agagtaaggg tgaaaaggtg aaagtagata aagcaattcg
      661 acctatcatc catcgactga cgaatcatca gaacaaacat cagttatggt cgtggtgggg
      721 gaactctgaa aatacttctt tctggatgtc tgcgcatatt ctgcgggctt tgaagatggc
      781 gcaagatgca ggttatcctg tggagttgaa tctgaatggt ttgaaagtgg agtatgctca
      841 tacgcgtcct tatcgaggaa tgaaactgga agatatagaa atacttcatg ctctgcatga
      901 gtggaaagta gaggcggatt attcttcggc agtcagatta ttggaacctt tcgtccggca
      961 attggaacag aaagaagact cgttggcaaa tagaaacaag tattatcgtc ctctttcata
     1021 cttgaaagag aagctgcttc tctgggaaat caagcaacag gtggattcgg tgaatgtggg
     1081 tgatagcgta cgtccttatc tgaaaaagga tatgctggaa ggtgtttact gtgacgacgg
     1141 acggcgtact tattattggg agggaaatca gatgataaat acattgatag cctaccggat
     1201 tattaaaaat gacccttccc tgtgtaagtt gaaagaaaat atgcaattgt atattttgcg
     1261 gactaaggag cgcggatgga atacgtatca ggcttcttcg gctgtggcaa ctgttctgac
     1321 cgatttgctg gcaggttccg gagggatgtc aggaacgtcg gtgtctgtga gcggtaagga
     1381 tcatcaacga attacggaat ttccttatca tgcccggctg acagcaagcg acagtctgct
     1441 tatttcaaaa acgggaaaag agcctttatt gtatagtgtc tattcaatga agcgtgtgat
     1501 gaatgctcgt cagagtgatg ctttcaaggt ggaggtgact ttggaaaaag actctttggt
     1561 ggcgggtgta cctgttacat tgacagttac cttgcaggtg aaacaggagg gtgcgcaata
     1621 tgtgatgctc gaagttcctg ttccggcagg ttgtagttat gcctcaaaac ctgttaattt
     1681 ctcccgttct gaagtatatc gtgagtattt taaagagaaa actgttatct ttagcgaaaa
     1741 attaccggta ggtacttatc agtttacggt tcctttgctt ccacgcttta ctggaaaata
     1801 tacgctgaac cctgtgaaag tggaactgat gtatttcccg gtggtgaatg caaataatgc
     1861 ggggggagaa atttggatta cagaaagaaa tacaaaagat atacgaaaga aagggaatga
     1921 ttgaagcgat gaaatatacg aagtggataa cagtcttgtt ttgtcttttg ggcttggcgg
     1981 cctgtcggca ggatgcgcct cgtttccgta ttggggtggc ccaatgtagc gatgactctt
     2041 ggaggcacaa gatgaatgat gagattcttc gcgaagcgat gttttatgat ggagtgtcgg
     2101 ttgaaatccg ctcggcggcg gatgataacc gtaagcaggc ggaagatgtt cattatttta
     2161 tagataaagg agttgattta ctgataattt ccgccaatga agcggctccc atgactccaa
     2221 ttgtggagga ggcctatcag aaaggaatac ctgtcattct tgtagaccgg aagatacttt
     2281 ctgataaata tactgcctat atcggtgccg ataattatga aataggtcgt gcggtaggaa
     2341 attatatcgc atcaagtctg aaagggaaag ggaatgtagt ggagcttacc ggactgggtg
     2401 gttccacccc tgccatggaa cgccatcagg gatttatggc tgctatcagc aattatccgg
     2461 atatcaaact gattgataaa gcggatgctg cctgggaacg tgaaccggca gaagtggaaa
     2521 tggatagtat gcttcgccgt catccgaaga ttgatgcggt atatgcacat aacgaccgta
     2581 tcgctccggg agcctatcaa gctgcgaaga aagccggacg tgaaaaggta atgatttttg
     2641 ttggcattga tgccctgccc ggcaaaggaa acgggcttga attggtgctt gacaatgtgc
     2701 tggatgcaac ttttatttat ccgactaatg gggacaaagt gatgcaactg gccatgaata
     2761 ttcttgagaa gaagtcttat cctcgcgaaa cggtcatgaa tactgccgtt gtagaccgca
     2821 cgaacgcgca cgttatgcaa cttcagacta cccatatctc ggaactggat cagaagattg
     2881 aaacattgaa cggacgtatc ggtgggtatc tgtcgcgtgt agctacgcag caggtcgtga
     2941 tgtatggcgg cttggttatt cttttattag tagcgggatt gttgttggta gtctataaat
     3001 ccctccgttc caagaatcgc ctgaataaag agttgtccga acagaagaaa caagtagagc
     3061 aacagcgcga taaactcgaa gagcaacggg atcagcttat ccagctttct catcaactgg
     3121 aagaagcgac tcatgccaag ctggttttct tcacaaatat atctcacgat tttcgtactc
     3181 cactgacatt agttgccgac ccggtagagc atttactggc tgattcgtct ttgagtgaag
     3241 atcagcgccg aatgttattg ttagttcagc gaaacgtgaa tatccttttg cgtcttgtca
     3301 atcagattct ggattttcgt aaatacgaga atggaaaaat ggaatatact cctatttcgt
     3361 tagacattct ttcttctttt gaaggatgga acgaatcttt catggcagta gcccggaaga
     3421 agcatattca tttctcattc gattatatgc cggatacgga ttaccgcaca ttggcagatg
     3481 tagaaaagtt ggaacgcatc tatttcaacc tcctttccaa cgctttcaaa tttactccgg
     3541 aaaacggaaa agtaactgta cgcttgtctt ccctgactaa agacgatcat tgctggattc
     3601 gctttaccgt tgccaatacc ggttcaatga tttctgcgga gcatatccgg aatattttcg
     3661 accgtttcta taagatagat atgcaccatg ccggttcggg tattggactg gcattggtaa
     3721 aggcttttgt ggaattgcat aaaggtacca tcacggtgga aagtgatgaa aagcaaggaa
     3781 ctatctttac cgttgatttg cctgtgcaga cttgcgagac tgttgtttct gaaaactctc
     3841 cggcattctc tgtgtctgct acttctgtaa cctccaccga tgctacaacc tctgccgttg
     3901 ctggggttcc ggcaactcct gcaacttccg gttattccgg ttcttcgagc ttgaatgatg
     3961 ctttaactta cgaagaagag gaattggaaa aaagttacga ctcttccaaa ccttgcgttc
     4021 tgattattga tgataacgct gatattcgct tatatgtgca tggattgctt catactgatt
     4081 atactgttat agaagctgca gacggctcgg aaggtattcg taaagctatg aaatatgtcc
     4141 cggacttgat tatctccgat gtaatgatgc ccggaatgga tggaattgaa tgttgtcgtc
     4201 gcttgaaaag cgaattacaa acctgtcata ttcctgttat cctattgaca gcttgttctt
     4261 tggatgaaca acgaattcaa gggtatgatg gtggtgcaga ttcttatatc tccaagcctt
     4321 tcagttcgca attactattg gcacgcgttc gtaatctgat agattcacac cgccgcctga
     4381 aacagttttt tggtgacgga caaacgttgg cgaaagagga tgtctgtgat atggataaag
     4441 actttgtgga aaaattcaaa gctttgattg aggcaaagat gggagattca aatttgaatg
     4501 tggaagactt gggtaaagat atgggattaa gccgtgtgca actctatcgc aaaatcaaat
     4561 ccctaactaa ttattccccg aatgaactgc ttcgtatagc tcgtttgaag aaagctgctt
     4621 ccctgcttgc ttcgtcggat atgacagtgg cagagatagg ttatgaagtt ggttttagtt
     4681 ctccttctta ttttactaaa tgttatagag aacagtttgg agagagtccg acagatttgt
     4741 tgaagaggaa aggataggat agaatctgca aaatttggtg gtgagcattt atctgtttat
     4801 acttctagaa ttcatatgat aaaaataaga ggtaaggaaa tctattgaca taccttacct
     4861 cttatttaat tcagtatatg atttactgta tatttattaa ttcataatca acttattcgt
     4921 ttttggctta ttccaccatc tttggttctc ttgacctccc gatgttaccc attgttcaaa
     4981 gtctggatat gcttccaaga agtttacttc ttctctggca tgatgtaaag atgcaggtac
     5041 ttttaatccc catataaagt tgtcttcatt tacataactt tcgttgctgt tataataaac
     5101 cgggctataa ccttttaagt ggatttcttg tcctttatta gtttttgcaa tataaaagtc
     5161 cattttactg tcttgtaggc ttttaacgtt aacaggtgag ttgaacacca agtaaatggc
     5221 catcattttt ttaggctttg ttttttcatt tacctccgta ttataatact tgtatccgtt
     5281 aggaatggcc ggtttcttta gtgaaataat caattcccct tttgggcctt ttaggatttt
     5341 gatattttca gcctcttcag gattgttacg ctcaagatac atttgagttt cttctaaatc
     5401 aagttcatta tattgtactt ctgccaagcg gatataagga ttgtagtcat atatacctcc
     5461 tatagctctg atttggaatc ctatcattaa gtattctgca taacattgat tgtgactcca
     5521 ataaaaaccg tcaatttgga aattatacca tgcaacaaaa tcattaaaat cataatcgcc
     5581 taaagctgga tacatatctt cgaacataat agttccgttg ccatatcccg gataattgaa
     5641 gatgttgttc gtttcaactt ctttattagc tcttgtggta actctggata atgccgtagc
     5701 gttagcaggt actactatag aaatagtacc attactttca acaggaacag tttgtatttc
     5761 agagccatta ccatatttta catacacatt ttttatatat gcaggaattt caattgggag
     5821 ttccaatttt gatgtgttgg catcgacatc cattcgaagc atcaaagcct cttcattgca
     5881 attttcttct agaaatacag aaatagtagc agttgattga ctggcaattt tcactttggc
     5941 attttgagaa cctttccagt cgaaatcggc aggtacttcc aagtcagtca tcttcttttc
     6001 tttctcgggt tgtttacttt catcataaag gttcttctca caggagctga aagccagtgc
     6061 tcccaataaa caagaagcga acaggatagt tttctttttc ataacagcag tgcttgtttt
     6121 gttaataata gggttgcttt taatgggtac aaaggtcggg attatttgta aataaagcaa
     6181 ataaagttgc atattttatt tgaaatgctt ttattatttg caaattcttt tctttttatc
     6241 tagttttgga actgaaataa agtaatgttt gagtgatgaa agattataaa gtagataagg
     6301 cgagcctttc cgcatccttt tgtcaagagg tgtatcaggt tgtccgagaa attccggtag
     6361 gtaaagtttc tacctatggg ggaattgccg cattattggg aatgtctcaa tgttcccgta
     6421 tggtggggcg tgctttgaaa cagattccgg atgatttatc tgcgccttgt catcgggttg
     6481 tcaatgcgtc gggacggctt gttccgggtt ggacagagca gaaacaactc ttgttggaag
     6541 aagggatctc tttcaaacaa aatggatgcg tagacttgaa aaagcatctt tggaattact
     6601 ccgtacctga atgaaatttg catatttaat ctattttcct tacctttgtg ccaacaatat
     6661 gcaagaacag actgttattt atttatgaaa atactgtttt ctactgttca ttaagaggat
     6721 aatcttatca aattctattc cttttaaact actctgtctg ttttttttta accatttaaa
     6781 aaacgtcgga ccgtcatgtt atcatgtgac atgactgaac catgcgaaca ttcaacttgt
     6841 ttatcgtaag tgagaataag gaatgcggca gttgaaaaca aaacaaatat tataatctaa
     6901 accaatatat tatatgagta aaatagaaat aaaggatttg taccttatct ttggtaacga
     6961 gaagcagaaa gccctcaaga tgttgaaaaa agataagagt aaagaggaaa ttctgaaaga
     7021 taccggttgt acggtaggag tgaaagatgc caatctttca attaatgaag gagagttttt
     7081 cgtgataatg ggactctcgg gaagtggaaa atcgacatta ctgcgttgta tcaatcgtct
     7141 gatacgtcct actaccgggc aagtgcttgt aaacggagta gatatatcta aaatttccga
     7201 aaaagaatta ttgcaggttc gtcggaaaga gctggcgatg gttttccaga atttcggtct
     7261 gttacctcac cgttccgtat tgagcaatat cgcgttcggc ctcgaacttc agggagtgaa
     7321 gaaagaggaa cgtgagaaga aagcgatgga aagcatgaag cttgtcggat tgaaaggata
     7381 tgaaaatcag atggtaggcg agctttccgg tggaatgcaa cagcgtgtcg gactggctcg
     7441 cgctctggct aataatcctg aagtgctttt aatggatgag gctttctctg ctctcgatcc
     7501 tctgattcgc gtacagatgc aggatgaact actggccttg caatcaaaga tgaaaaagac
     7561 gattgttttt attacccacg acttgagtga agcaattaag ctaggtgacc gtattgccat
     7621 catgaaagac ggagaagtgg tgcaggtagg tacttcggag gaaatcctga ctgaaccggc
     7681 taacgattat gtagcccgtt ttgttgaaaa cgtggatagg agcaaaatta ttaccgcctc
     7741 ttctttaatg attgacaaac cgttggtggc ccgtctgaag aaagaaggtc ccgaagtatt
     7801 gattcgtaag atgcgtgcga agaatatcac cgtattacct gtcatagacg ccgatgataa
     7861 actggtcgga gaagtacgtc tgaacgactt gcttaagtta cgtagcaaac aggaaaaatc
     7921 cattgaaacg attgtgcgta cagaagtaca ttctgtgttg gaggatacgg tgttggagga
     7981 tatacttcct ctaatgacaa agagcaattc gccggtatgg gtgattgatg agacgcgcga
     8041 gtttttagga acaatcccgc tttcatcctt aatcatcgaa gtgaccggga aagataaaga
     8101 agaaataaac gaaataattc aaaacgcaat agatttatga taaatatagg acaatatata
     8161 gagatggcca tcaattggat gatgatacat ttttccactt tctttgatgc cgtgaatgcg
     8221 ggcatcggta gttttattat aggattccaa cacatacttt tcggaatacc tttttatata
     8281 accattttgg tacttgctgc actcgcatgg atgaaagcag gacgcggtac ggcaattttc
     8341 accgcattgg gattattact gatctatgga atgggattct gggaggctac catgcaaact
     8401 ctagctctcg ttttttcatc tacctgtctg gccctgattg ttggtgtacc tttaggagta
     8461 tggacggcaa acagttcgcg tgcagagaaa atactccgtc ctgttctcga cttgatgcag
     8521 acgatgcctg cttttgttta tctgattcct gctgttttgt ttttcggatt gggagcagtg
     8581 ccaggagtgt ttgccaccat tatctttgct atgcctcctg tggtccgcct taccggattg
     8641 ggaatccggc aagttcctaa aaatgtagtg gaagcttccc gttcgttcgg agctacccgt
     8701 tggcagttat tgtataaagt gcagcttcct ttggcgttgc ccaccattct gactggtgtc
     8761 aaccagacaa taatgatgtc gctttctatg gttgtaattg ctgccatgat tgctgccggt
     8821 ggtctgggag aaattgtatt gaaaggtatt acccaaatga aaatcggact tgggtttgaa
     8881 ggtggtatag cagttgttat tttagctatc atcttagacc gtatcacgca aggaatggca
     8941 ggacgaaaaa ataagaacta aacggaaagg ataaaatacg tatgagaata tataaaatag
     9001 taggaatagt attgtcagct atgcttttgc tagcttcctg tactaattca gacttagaga
     9061 aaaagaaagt aaaaatagcc tatgccaatt ggctggaagg tattgccatg agtcatttgg
     9121 ctaaggtggt attggaagag catggatatg aggttgaatt gcaaaatgct gatcttgccc
     9181 ctatttttgt atctatgtca ggaaagaaat cagatgtgtt tctggatgca tggttaccaa
     9241 taacgatgaa agattatatg gatcagtatg gagacagcat cgaatttttt ggggaggtat
     9301 acggagaagc tcgcgtcgga ctggttgttc ctcaatatgt tacgatccac tctattaatg
     9361 agctggaagc taataaagac cgtttttcct ctgaaatagt aggaattgat gcgggagcag
     9421 ggataatgaa gacgaccgat aaggccattg ctgcttacgg acttgatggg tataccctca
     9481 tgacttcaag tagttccacc atgctggctt ctttgaaaaa agcgatggac aaaggagaat
     9541 ggattgtcat tacggggtgg acaccgcatt ggatgttcga ccagtttgac ttgaaattct
     9601 tggatgatcc gaagaaagta tatggagact tggaagaaat acatgctatt gcatggaaag
     9661 gattcagtga gaaagatccg tttgctgccg aattctttgg caacatcaaa ctaacgacag
     9721 aagaacttag ctcttttatg acagctatga aggatgccag gatggatgaa gaagaaatag
     9781 cccgtaaatg gagggatgag catcggctgt tggtggatag ttggattccg aagtcagaga
     9841 ataaatagat tggagcattg ttattcttaa ttttaaatat aaaatagaca tgaactctag
     9901 tgggaaaaag ggagtactgt ttatgttgga cagagttcat acaataaaaa agcggtaatc
     9961 tttgataaga ttaccgcttt atatttatag ggtattacta ttattcagca ccccagtttt
    10021 ctctagccaa acgtttgtag ctgttgtaac gccatttagc gttttcttca gcagctttaa
    10081 acagttcttc agcttcagta ggatattgtt tcattacaga agcgtaacga acttcaccct
    10141 tcaagaaacc ttggaaatct tcccagttcg gttctttgct atccaattgg aatgggttct
    10201 tgccttcttc ttccaaagct gggttgtaac gccacaagtg ccagtaaccg cacttaacag
    10261 ctttttcttc ttcttcctgg ctcttaccca tacctgcttt cagaccgtgg ttgatacatg
    10321 gagcgtaagc gataatcaaa gatggtcccg gatatgcttc agcttcacgg atagctttca
    10381 gagtttgagc ttggtcagca cccatagcga tctgtgcaac atatacataa ccgtaagtag
    10441 tagccatcag accgaggtct ttcttacgta cgcgcttacc agcagcagcg aacttagcga
    10501 tagcacctac cggagtagcc ttagaagact gaccacctgt gttagagtaa acttcagtat
    10561 ccagaacgag gatgttaacg tccttaccgg aagcgattac atggtcaaga ccaccataac
    10621 cgatatcgta agaagcaccg tcaccaccaa tgatccattg gctgcgtttt acaagatatt
    10681 gagtcagtcc tttcagttct ttgcaaatag gacatccgtg agaaagacct tcttcaatca
    10741 ctgctttcac ttggggagcc aattctttag tcttgtcagc atcgtacatg ttttcaatcc
    10801 atgctttcag cacttctttt gcttcaggtg aagcgttgtc ggcagcaagg atttcgttga
    10861 ataacttcac gatacgagca cgcatctttt cgttagccaa ttccataccc aaaccgaatt
    10921 cacagaagtc ttcgaacagt gagttagccc aagcaggacc gtgaccgttt tcgttcgtag
    10981 tatacggagt agaaggaact gaaccagagt agatagaaga acatccggta gcgttagcaa
    11041 ccatttcacg gtcaccgaac aattgagaaa tcaatttcac atacggagtt tcaccacaac
    11101 cagagcaagc accagagaac tcaaacaacg gagtagcgaa ctgtgagttc ttcacgttag
    11161 acttgatatc aacaagatgt tgtttagtct tcacgttttc agcacagtaa gtccagttgt
    11221 cagcttcagc caattggctt tcgaggtgtt tcattgtcaa tgctttgcca cccttcttcg
    11281 gattacccgg acagatgtca gcacagttac cgcaacccag acagtcgaga acgtcaacct
    11341 ggatacggaa tgtcataccg tcgaatactt tacctactgc tttcaattgt tcgaacttag
    11401 cacccttctg ctcttcagca tcgagtacga acggacggat agaagcgtga ggacaaacgt
    11461 atgcacactt gttacactgg atacagtttt ctggattcca ttcaggaacg aatgcggcta
    11521 caccacgttt ttcgtattta gaagtacctt gataccaagt accgtcttcg atacccttga
    11581 atgcagatac aggcagcaag tcaccatctt gtgcattgat cggacgaact acttcgttga
    11641 tgaatgcagg atcgttgttt tcagcttttg catcatccgg caggttagcc caagcaggat
    11701 caacagctaa agtcttgtat tcaccaccac ggtcaacggc agcatagttc ttgttaacaa
    11761 cgtcttcacc cttcttaccg taagacttaa cgatgaattt cttcatctgt tcaacagcct
    11821 ggtctacagg aataacacct gtgatacgga agaatgcaga ttgaaggata gtgttggtac
    11881 gattacccaa accaatttcc aatgcaatct gtgttgcgtt gatatagtat acggaaatgt
    11941 tgttctgtgc aaaatatttc ttaaccttgt taggcaggtt cttagccagt tcttcacctt
    12001 cccagatagt gttcagcaag aaagaaccgt tcttacgcaa accacgagtt acatcgtaca
    12061 tgtgcaggta agcctgaacg tgacaagcaa cgaagttcgg agtatttacc aaataagtgg
    12121 aacggatcgg agtatcaccg aaacgcaagt gagaacaagt gaaaccacct gacttcttag
    12181 agtcataaga gaagtaagcc tggcagtgtt tgtcagtgtt gtcaccgata atctttacag
    12241 agttcttgtt agcacctact gtaccgtcag cacccaaacc gtagaattta gcttcgaaca
    12301 ttccttcacc gcctaaagcg atttcttctt tttgaggaag agaagtgaaa gtaacgtcgt
    12361 ctacgatacc gatagtgaag tgattcttcg gcattggcat ggccaagttc tcgaatactg
    12421 aaagaatttg agcaggagta gtatcttttg aacccaaacc gtagcgaccg ccaacgataa
    12481 ccggagcatt ttctgcgccg tagaagcagt ctttaacgtc aaggtaaaga ggttcgccgt
    12541 tagcgcccgg ttctttagta cggtcaagaa ctgcgatagt cttggcagtc ttaggtacag
    12601 cagccaggaa gtgtttagca gagaacggac gatacaggtg tacggcaacc atacccactt
    12661 tttcgccatt tgctaccaag tggtcgatag cttcgcgggc agcttctgtt acagaaccca
    12721 tagcgataat tacgcgttct gcatcttctg caccataata atcgaacaaa ccgtatttac
    12781 gacctgtaat cttagaaatt tcattcatgt attcttctac gatagcagga actgcttcat
    12841 agtagttgtt gcatgattca cgatgttgga agaaatggtc aggattttca gccataccac
    12901 gagcaaccgg attcatcgga ttcagtgcgc gggcacggaa ttcagccaaa gcttcctgat
    12961 caatcagcgg agcaagatca tcattttcca acatttcaat cttctggatt tcgtgagatg
    13021 tacggaaacc atcgaagaag ttcatgaacg gaacacgaga tttgatagta gccaagtgag
    13081 caacaccagc caaatccata acttcctgta cagagccttc agccaacatc gcaaagccag
    13141 tctgacgagc tgacattacg tcttggtggt caccgaagat acacaatgcg tgagaagcca
    13201 atgtacgagc agatacatgg aatacgcaag gcaagaactc accggcaatt ttgtacatgt
    13261 tagggatcat caggagaaga ccctgagaag cagtgtaagt agtagtcaac gcaccagcct
    13321 gaagagaacc gtgaactgca ccggcagcac caccttcaga ttgcatttcc tgtaccaata
    13381 ctgtttcgcc gaagatgttc ttacgtcctg cggcagccca ttcgtctacg tactcagcca
    13441 tagtcgaaga aggagtgatg gggtagatag cagctacttc agagaacata tacgagatat
    13501 gcgctgcagc ctggttacca tcacaagtga tgaatttctt ctgtttagtc ataactaaat
    13561 taaatattta agtaaataaa tcttttaata taaaaagccg aacatccaga gaggtatctg
    13621 gttgccccga cctatttcag ccttatgcaa cgcgtacgtc acattcggat tgttcttgat
    13681 ctttgctcct tcctggcaaa ttttgaacgg cattacttcg tccaccataa aagagacgtt
    13741 tttatctcct ttatgtacct tatggtcttt ccataaagaa ttcacaaaga aagtgtcgag
    13801 cacatcctgc tcctccactt tcaccgggta gatggaatac atcaggttgg agttgtgcat
    13861 cattatcttc gaaggttttt tagggaattc ttcccctttc ggataaacca gattaatgag
    13921 tcgcgcatct gccagatact tgatatagtt catcaccgtg gcgcgagatg tctgtatgtc
    13981 gcttgccagt tggctcacat ttggagcttt cggcccgtcg acagcgagca aatatagtaa
    14041 tttttttatc tttgaaagat atttcagttc aatttgtttg atgagaagta tatctacttc
    14101 caccatcatg ttcatcgttt tcagcaaatt ctccgagaag ttacgcttct cgaggaagaa
    14161 cggatagaac ccatgatgca ggtaatcctg gaagtaatcc agcggacgaa ctttagagag
    14221 tactcctttg gcaatctgtt cgtgagtgct aagaatttct tcgaggctgt atgccctgaa
    14281 tttcatgcct gtctgtaagt tcaggtattc gcgaaaagaa aatccgcgca ggttatagct
    14341 cttggcgata tcacgtaatt caagattttc ttctttcagt cgcatcacgg acgagccggt
    14401 gaagacaatt ttcaggttag gaaaacggtc gtaacacatg cgtaactctt tgctccattc
    14461 cggatgtttg aacacctggt cgatcaacaa tacttttccg ccacgtttct gaaattcgtt
    14521 agcaaagtct acaatgctgt ggccagagaa gtagaagttg ttcatgttga tgaacaggca
    14581 ggagcggtcg ttcccaaatt tttctttggc gtattggaga aggaaagtgg tttttcctac
    14641 gccacgtgtc cctttgatac caatcaggcg gtcgctccag tcgatctcgt ccataagatc
    14701 gcggcgaacg ggggcattgg tgtgctcaac gaggtaggcg tgtgtgcgat agaatgattc
    14761 catttcagtt ctttgttttt cgggtggcaa atatactgct ttttttagga tttgcaaagt
    14821 agagatggca aaattgtgag tttaattaga actttctgtt tattgtagcc attcctgact
    14881 atttcctgta tatatttgca gaataaagtt ttgaattcgt ttaaaatgac aaaaaaggct
    14941 ctttatatat tcaatccgga acatgatttg gcgttagcca gcggtgaaac aaactatatg
    15001 gcaccggctt ccgcccggca gatggcatcc gaattggctt tgttgccgat gtggtatgca
    15061 gaagagggaa gtgttgtatt ggctccttcc gcttataatc tcgactatgt gaagaagata
    15121 caggaattat taggactttc ggttgatttg atgacagaac ctgaacttgc ttcggagcgg
    15181 aatttggata ttcgtccttg gggctgggat atagcaataa gaaaacgact gttggatttg
    15241 ggagtggaag aaagcgagct tccttctatt gagcaattgg ataaactgcg tttctgttcc
    15301 catcgttcct gcgctgtggg attattacca cagctacaac tgggagcctg tttttgtgga
    15361 gagtcttttt acctgacgtt tcccgaagaa tggaagtcat ttgtagaatc acatgatact
    15421 tgtttactga aagctccttt atccggtagc gggaaagggc tgaactggtg caaaggtgta
    15481 tatactcctt ctatttccgg ttggtgctca cgcattggca aacagcaagg aggtgttatt
    15541 ggcgaacctc tatataataa ggtggaagat tttgctatgg aatttcgttc ttcgagtaat
    15601 ggtcgatttg gctttgccgg atactctcaa ttccgtacgg gtggaagtgg ggcgtacgaa
    15661 ggtaatctgc tgatttcaga tgcagccatc gaacggaatc ttttggaata tatccctgtc
    15721 gaagaaattt ataaattgcg cgaccgcctt gaacaagaat tatccctccg tttcggaacc
    15781 atttataatg gttatttggg agtggatatg atgatctgtc gctttccaga atctcctgtt
    15841 tatcggattc atccttgcgt ggaaatcaac ttgaggatga atatgggagt agtagcgcgt
    15901 catatttatg accattatat ctatcctact tcaacaggag cttttcaaat aagctattac
    15961 cctacggaag gaacagcctg gagagcacac aaagaaatgg aggaggctta tcctttggaa
    16021 atagaacaag gaagaataaa atcaggctat ttgtcattgg tgccggctca taaaaagagt
    16081 agttatcggg cgtgggtgtt tatctcaaaa agcgtgtttt tgtgatatta tatcgaagtt
    16141 atggtttctc ggtgtgaaac tgatagtttc atgtagtgaa accattggtt ccacaccgag
    16201 aaacaaaaag tttcattgca tgaaacaagt aatcacatgc catgtgtgta ctgtactgga
    16261 tttagttgac aacttcgctt gttataccta agttagttta ctcaatattt tttaaaacct
    16321 aaataagttt acttgtccct ttgtaattcc tgtataagtt gtcatttaag ata
//
