LOCUS       gnlProkkaEFBBDKOM_167  14458 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EFBBDKOM_167.
ACCESSION   gnlProkkaEFBBDKOM_167
VERSION     gnlProkkaEFBBDKOM_167
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 12:25:46
            Original ID  :: gnl|Prokka|EFBBDKOM_167
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14458
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14458
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2838:4458]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2839..4458
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14458
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14458
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             139..405
                     /locus_tag="ctg149_1"
                     /transl_table=11
                     /translation="MKKRSNFTPMERFHKILIGHGLNAMNVGINHIRIFLDGKKLFDYY
                     PLRMKLFDYHNWYQLTYPSFLEGVDKWETELDGIIKKLMISLQ"
     CDS             complement(665..2842)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 285.7; E-value:
                     1.3e-86)"
                     /gene_kind="transport"
                     /locus_tag="ctg149_2"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.4e-36, bitscore:
                     115.4, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRFRVSYQHDSMQCGAACLRMVCKHYGKEYALDFLSEQCGCMIDG
                     VSLQAIRETAEDLGFRTFAVSVGLSELQAGWCPCILHWERNHFVVLYRIHKDKYHVADP
                     AKGTVIYRKEDFLKRWAGDGEQGIALLLEPTQAFYDFSSGMEPKVPSPFRFLWRYIASY
                     KKAFASVALTLLVGSLVQLVLPLLAQMMVDKGIGHKNIPLVYLILGGQLVLVLGSAAME
                     FVRNRLLLFVGMHVNISLITDFFAKLFRLPISFFETRTTGDLLQRIVDHRRVQDFLTGQ
                     VLSVLFSVMVLCIFMGVLFSYNSFLFLVFLAGSIGYGLWTMCFLHKRKLFDYMIFEKQS
                     ASNNKVYQLLTFMQEIKLQGGEGRRAGEWEALQKELLDIQMRSLSLQQFQQTGGIFISQ
                     SKNLVVTVIAAVAVIEGEMTLGMLLAVQFIIGQLNIPIEQLMQFLYNFQNVRLSIERIS
                     AIHGKAEERTGKEIPEQPEISRKDIRIEHLDFKYNLHGKAKVLDDITLTIPAQRTTAIV
                     GASGSGKTTLVKLLLGYFAPTSGNIFLGDTPLQDYDMTSWRHSCGVVLQDSHVFSESLA
                     RNIAVEDKHIDRTRLRTAARQANLEEFIEKLPLKYQTMVGAEGVGLSRGQEQRIFIARA
                     LYKDPSFVFLDEATNSLDANNERIITGNLLDFCKGRTVLIVAHRLSTIRHADKIVVLHK
                     GRIVEEGTHDELCARHGHYYELINNQLIAMG"
     CDS             complement(2839..4458)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Other_Sactipeptide_rSAM_RRE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg149_3"
                     /sec_met_domain="Other_Sactipeptide_rSAM_RRE (E-value:
                     6.5e-20, bitscore: 61.7, seeds: 13, tool:
                     rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKFPLVKLFTVDGASCYLYDGRANMFLSLSETEKNLVCEYMASY
                     GTTEGEPCPASFPSGAAAFIARLNGNGILLPGPLEARTPSGMRGEEQLWQQWEEEAIPK
                     KLTLEMTNTCNLRCRYCPYTINEQRGQGKMHASHHLKEEDARKAISDYFHEYTRIFRKV
                     EPEHRTLFLKRNPPAVSFYGGEALLRFSLLEPLVKYVLSLPWEEHHIPAEKVVYHITTN
                     ATLLTREMVEFFIRYHFTLAISFDGPPEENDKYRVFKNGQGTGTVVERALDMIREVSEE
                     YLLNHVHIQAVLAPEYDHDKVGRYFEGRSLNGCYGGVRQFSYLEFSDYSESKKTDKQLA
                     QFNIRERIKELYEKGLSPEERYQYILRDPLISAWLRYVYAILTKVGDAPSHKARYFNSC
                     YIGRTNLLLDTYGNLHLCERSDFSMPVGEVNSGINRTAVRQMYRDFFEKTDSPSCRSCW
                     AGRFCTLCTAALIKNGAVQEPDRSICRSLRHAQEKQIEDLLYIKEYYPEILEQMERMYF
                     QANDITLGAFHAYVKEQQDVAP"
     CDS             complement(4514..4708)
                     /locus_tag="ctg149_4"
                     /transl_table=11
                     /translation="MGKQIAKLGIRPEDLKDKTVTSEQLEKTKGGKAAGSEECVCYCGC
                     YTDDSAFGVDFNWWSRDWD"
     CDS             complement(5130..5795)
                     /locus_tag="ctg149_5"
                     /transl_table=11
                     /translation="MEEIVYLSVRIGCAGYLLYKLWNQKKRIRKICGLLYTPGKKEKEE
                     EGTSCGTGPGDVMGATRFVYLDENAGTFAAPYMSQPLETGNDYLGEEEAVPENEVECGL
                     PLEEMRLLKEEQERLDEQAPGTEGITPVITSDDLLNAGDVLLNLDGAQMNEEKKRRAAV
                     TLHAIRETDMFELISSQVENKSLIEELMDQYIGNDGNVLPVKRKKNEGQPEHAWRQFL"
     CDS             complement(5783..6235)
                     /locus_tag="ctg149_6"
                     /transl_table=11
                     /translation="MATKRRTDYQVDEEALKRMMAGDVTALDKMVSPAEAPETISRPAP
                     SQEKQEKNSAGSPKQQIRKSTDEASGPDEYRQRFLKERLSGSRRQTYIHDALYRTVAKL
                     LPVIAPDMSVPMFLGSVLSDHLERYQDVINEIYNQEANQNPLEWKK"
     CDS             complement(6244..7005)
                     /gene_functions="other (smcogs) SMCOG1157:hypothetical
                     protein (Score: 76.8; E-value: 3.3e-23)"
                     /gene_kind="other"
                     /locus_tag="ctg149_7"
                     /transl_table=11
                     /translation="MKKEPLFVALSNQKGGVGKSTFTVLLASYFHYLKGYNVLVVDCDY
                     PQHSISTMRDWEVGTIEKNVHLQNQLVEQFGTSGRKAYSILNSTPEEARETAGRFLEKS
                     GLDYDLVLFDLPGTVNVPGVFRSVINMDYVFTPVTQERMVMRSSMAFVLAIREYMHRHK
                     DVPLRGIYMFWNRMDKRVSKDLYNSYTEIFRSLKLPAMETVIPSAERYNKDFGMKGFFF
                     RSTLFPPTPSALRGSNLDLLATEIETILKLQ"
     CDS             7769..8191
                     /locus_tag="ctg149_8"
                     /transl_table=11
                     /translation="MEKTTGTRTGRKPKNDPADRKYSFRLNAEENTRFERLLADSGARD
                     RTLFIKKSIFSGQIKVVRIDKATIDYYIKLTEFHKQFQAIGNNYNQVVRALKNNFGEKR
                     AMSLLYRLEKLSVELMLLCKKITALTQEYERKWLQR"
     CDS             8176..9432
                     /locus_tag="ctg149_9"
                     /transl_table=11
                     /translation="MVAKISHGASLYGALAYNHNKVATGAAGILSGNRMISDRLGLPSE
                     DMRLALLSFENYLLANRNTEKPVLHISLSPAPEDRLTDDQLAELADRYMRKMGYGDQPY
                     IAYKHADTHNAHIHIVSVCVDEQGKKISDSYEHRRSMTACRELEADFGLRNGADTEKRN
                     PKAELKKVDASLGDVRHQIGNTLKAVLESYRFQTFGEYSALLSTLNIEAKQVRGEYHGV
                     PYTGIVYAATDDAGKVVSPPFKSSRFGKRFGNEQLEKRMLLNLKALKEGKWAPSIQADI
                     AHALQQADSRQRFVELLGQKRIGVVFRENEQGRIYGVTFIDHDRREVFNGSRMGKEFSA
                     NVFNDYFRWLDGISENDRNGHTAVELWQHHRHKAGPESALEQAAGILSLETNPRDYQEE
                     AFARRMKKRKKAKRKSRGI"
     CDS             9472..11505
                     /locus_tag="ctg149_10"
                     /transl_table=11
                     /translation="MQQEDDLRALAKIMEFGRAVSIFLLVVHVYVYCYPSITAWNLNLE
                     VTDRILVNFNNTTGIFNCILWTKLLAVTLLAISCLGTHGVKGEKITWPKIYAALVAGCV
                     LFFLNWWLLDLSLPHMTSTILYVITLTAGYLGLLMAGLWMSRLYRHNLMGDVFNIENES
                     FQQETRLLENEYSVNLPTSFRFQEKQHDGWINVVNPFRATIVLGTPGSGKSYAVVNNYI
                     RQMISKGYSCYIYDYKFDDLSTIAYNTLLNNMDKYKVKPRFYVINFDDPRRSHRCNPIN
                     PEFMTDISDAYEASYTIMLNLNRTWIEKQGDFFVESPIILLAAIIWYLKIYKNGIYCSF
                     PHAVELLNKPYSDLFTILTSYPELENYLSPFMDAWKGGAQDQLQGQIASAKIPLTRMIS
                     PQLYWVMTGNDFSLDINNPKEPKLLCVGNNPDRQNIYSAALGLYNSRIVKLINKKGQLK
                     STVIIDELPTIYFRGLDNLIATARSNKVAVCLGFQDFSQLNRDYGEKESKVIQNTVGNI
                     FSGQVVGETAKTLSERFGKVLQQRQSVSINRQDVSTSISTQLDSLIPASKIANLSQGTF
                     VGAVSDNFGEKIDQKIFHAEIIVDHAKVSAEEKAYRKIPVINEFKDKDGNDIMMQQIQR
                     NYDRIKLDAQAIINEEMNRIKSDPELCKRLGLDDEKSSKKKE"
     CDS             11502..11609
                     /locus_tag="ctg149_11"
                     /transl_table=11
                     /translation="MIHLPLNLHEVCGKRYKSFPHTIIALYDNAYMTGV"
     CDS             complement(11591..12154)
                     /locus_tag="ctg149_12"
                     /transl_table=11
                     /translation="MNRIIYQTVEDRENPDYVEQHGPFICTNKNAWLGEGYYFWDTIIE
                     LAHWWGNLCYKDSGYIICQSACDDKLEKVFDLVGRPEHLIEMKRCSEIITKKWHKSTVY
                     VPEIIAYLKQFTQFSTLYKAIRVNPLCTLPNSYIQSSLFRFNNRNKAFIDVCPAIQFCF
                     FDKSLFTEDYLIVYPEMYCQTPVI"
     CDS             complement(12165..12581)
                     /locus_tag="ctg149_13"
                     /transl_table=11
                     /translation="MQQAVFSLKNYSVVKVMLDLENIPPQCIFDLKIEPSGIYFQRERQ
                     YVLNLVFKASYKKENTDFEVINIKLKAVFSFGDMVQTDTIPSYFYANSIAIIFPYVRAF
                     VSTITLQANVAPIMIPTLNVSLLERELRRNTVLK"
     CDS             complement(12601..12861)
                     /locus_tag="ctg149_14"
                     /transl_table=11
                     /translation="MKRLSEELLEYFSNTPEEQLQKDWEAIHSKYAYGPEINQFIEECE
                     KNALHNEIVDGIYGSHPTSRVNVESPISQDFGSDSYLPMAV"
     CDS             complement(13036..13404)
                     /locus_tag="ctg149_15"
                     /transl_table=11
                     /translation="MENLIQIHSVKNVLSHSGCPEDLLESYLKFLQTGGQQVQIVRGEV
                     TMMFQKEMQYRKRRNEEMKGTVTFSNKDKHNAGNSDMGVFIGMEFIQCCFGHGIPARVL
                     DVRRVRGEVVEVVVEFGK"
     CDS             complement(13411..14313)
                     /locus_tag="ctg149_16"
                     /transl_table=11
                     /translation="MDRGILLNQFNLSVVFFLRIESDYNYTRDYVENVARNFTQKYPSY
                     LIHKKSEDKIRAFLTDTVKVKVETFADAETKNVTVTEVREIADLIAEYEGMEGERNSSS
                     SFGNHPTDAPSLGSTGVELAMSMDNGASDIRPINVAKPTGASGKPKIMKRSVIRVTMEL
                     EVLMETKQYLHFLQELPELFSLHEFPNLRCRVTWKQKRVSYQESPLPIEVKVVEDRKYQ
                     RWFVTFTVLMVLCFIGIITLFFSIPNLYKQDIHFLRNDTIHQEFSISNSRIDLKNVNLM
                     NNGGKDTLVVKDKKIIIAK"
ORIGIN
        1 tcgtggggta aggggatggt ggctacatat tgatgttgtg ctgttgcttt ttactgaaag
       61 ctgctactaa cgactcataa atctaccctt aatcgtgtat tggatgatag ttgcggattt
      121 tagggtaata aaaaaattat gaaaaaaaga agcaacttca caccaatgga aagattccat
      181 aaaattctta ttgggcacgg tctgaacgcg atgaatgtgg ggattaacca tatccgcatt
      241 ttcttagatg gtaaaaaact cttcgactac tatcctctga gaatgaaact gtttgattac
      301 cacaactggt accagctaac ctatccgtct tttcttgaag gtgtggataa atgggaaacg
      361 gaacttgacg gaatcatcaa aaaattaatg atatcactgc aataagtatt ccggttacga
      421 aagaaaacaa taacacaacg ctcgtttggg acaacattcc tgaatgagcg ttttttcatt
      481 ggtcaagtgt aatgagaagc caaaagtagc actctaaggg ttgatgcaac tggttccatt
      541 atataataga gattgttttt tagatatagt ttatactcta ttgtcaaaat acggaaaaca
      601 aagaaaaaag caagaccttg acgaaaaggc ttttttgaca tataaaagtt aaaaaatact
      661 atcttcaccc catagcaatc aactggttat taatcaactc ataataatgc ccatgacggg
      721 cgcacaattc gtcatgggta ccctcttcga caatcctgcc tttatgcaga acgactatct
      781 tgtcggcatg acggatggtg cttaaccggt gggccactat caggaccgtc cttcctttgc
      841 agaaatccag cagattcccg gtaatgattc tttcattgtt ggcatccagc gagttggtag
      901 cctcatcaag aaacacgaac gaagggtcct tatagagcgc acgggcgata aagatacgct
      961 gttcctgtcc ccggctcagc cccacgcctt cagcccccac catcgtctgg tatttcaagg
     1021 gcagtttctc tatgaactct tccaggttgg cctgacgggc ggcggtccgg agacgtgtac
     1081 ggtctatatg cttgtcctcc actgctatat tccttgccag agattcggaa aacacatggc
     1141 tgtcttgcag cactacgccg cagctgtgcc tccacgatgt catatcataa tcctgcaagg
     1201 gagtgtctcc caggaagata tttccgcttg taggagcaaa atagcccagc aacagtttga
     1261 caagggtggt ctttccgctt ccgcttgcgc ccacgatggc ggtggtacgt tgtgccggaa
     1321 tggtcagcgt tatgtcatcc agcaccttgg ctttgccatg caggttatat ttaaaatcca
     1381 ggtgttcaat ccggatatcc tttcgggaaa tctccggctg ttccggtatc tctttccccg
     1441 ttctttcctc cgccttccca tgaatcgcgc tgatacgctc gatgcttagc cgcacattct
     1501 ggaaattata gagaaactgc atcagttgtt caatcgggat gttcaactgc ccgataatga
     1561 attgcacggc aagcagcata cccaaagtca tctccccttc aatgacagca acggcggcaa
     1621 tgaccgtcac aaccaggttc ttggactggc tgataaatat cccgcctgtc tgctggaact
     1681 gttgcaggct caaagacctc atctggatgt caagaagctc cttttgcaac gcctcccatt
     1741 ccccggcgcg ccttccctcg ccgccttgca gctttatctc ctgcatgaaa gtaaggagtt
     1801 ggtatacctt gttgttgctg gccgactgtt tctcgaaaat catatagtca aacaacttgc
     1861 gtttatgcag gaaacacatg gtccacaggc cgtagccgat acttcccgcc agaaagacaa
     1921 ggaacaggaa gctgttatat gaaaacagga cgcccatgaa tatgcacaag accattaccg
     1981 agaacaagac ggagagaacc tgtccggtaa gaaaatcctg caccctgcgg tgatcgacga
     2041 tacgctgcaa aagatccccg gtggtccttg tctcgaagaa tgaaatcggc aggcggaaca
     2101 gtttggcgaa gaagtcggtt atcaatgata tattgacatg catccccaca aacagcagaa
     2161 gacggttgcg gacaaactcc atggcggcag aaccaagcac aagcaccagc tggccgccga
     2221 gaatcagata gacaagcggg atatttttat gaccgatacc tttgtcgacc atcatttgcg
     2281 caagcagcgg aagcaccagc tgtacgagac tgccgacaag cagggtcaag gcgaccgatg
     2341 caaatgcttt tttataagaa gctatgtacc tccataaaaa acggaaaggg gacgggactt
     2401 ttggttccat gcccgaagag aagtcataaa aagcctgtgt gggttcaagt aacaaggcga
     2461 ttccctgttc cccgtctccc gcccaacgct tcaggaaatc ttctttccgg tatatgaccg
     2521 tccctttggc cggatcggca acatgatact tatccttatg aatcctgtac aggacgacaa
     2581 agtgattacg ctcccaatga aggatacagg gacaccatcc ggcctgcaat tcggacagac
     2641 cgaccgatac ggcgaatgtc cggaatccca ggtcctccgc cgtctcgcga atggcctgca
     2701 aggaaacccc gtcaatcatg cagccgcatt gctcggaaag aaagtcaagg gcatattcct
     2761 ttccgtaatg cttgcagacc atacggagac acgccgcacc gcactgcatg gagtcatgct
     2821 ggtaggacac cctgaacctc atggggcgac gtcttgttgt tccttgacgt aggcatggaa
     2881 agcgccgagc gttatgtcat tcgcctggaa atacatacgt tccatctgtt ccagaatttc
     2941 cggataatac tccttgatat acagcaagtc ctctatctgt ttctcctgtg cgtgccgcaa
     3001 gctcctgcaa atggaacggt caggttcctg aaccgcaccg ttcttgataa gcgcggcggt
     3061 gcagagggta cagaagcggc cggcccagca ggaacggcag gacgggctgt ctgtcttctc
     3121 aaaaaaatca cggtacattt gccggacggc ggtacggttg atgcccgagt tcacctcacc
     3181 gacaggcatg gagaaatccg accgttcgca gagatgcagg ttgccgtatg tgtcaagcaa
     3241 cagattggta cgcccgatat agcatgaatt gaaatatctg gctttgtgtg agggtgcgtc
     3301 accgaccttg gtcagaatgg cgtacacata ccgcagccat gcgctgatca gggggtcacg
     3361 aagaatatac tggtaccgtt cctccggaga gaggcccttt tcataaagtt ccttgatccg
     3421 ctcccggata ttgaactgcg ccagttgctt gtccgtcttc ttgctttcac tgtaatcact
     3481 gaattccagg taggaaaact gacggacccc gccataacaa ccgttcaggc tacgcccctc
     3541 aaagtatctg ccgactttgt catggtcgta ttcgggagcc agcacggcct gtatgtgtac
     3601 atggttcagc aggtactctt ccgaaacctc acggatcatg tcaagggcac gctccaccac
     3661 cgttcctgta ccctgcccgt ttttgaacac gcggtacttg tcattctcct ccggcggacc
     3721 gtcgaagctg atggcgagag tgaaatgata ccgtataaag aattccacca tctcccgtgt
     3781 cagcagcgtg gcattggtcg ttatgtggta tacgaccttc tccgcaggta tatggtgttc
     3841 ctcccaagga agcgagagca catatttcac caacggttcc agcagggaaa aacgcagaag
     3901 cgcctctccg ccgtagaaac tgacggcggg aggattccgt ttcaggaaca gtgtcctgtg
     3961 ttccggttcc accttgcgga aaatacgtgt gtattcatgg aaataatccg aaatggcttt
     4021 ccgcgcatcc tcctctttca agtgatggga ggcgtgcatt tttccttgtc cgcgttgctc
     4081 gttgattgta taggggcaat acctgcaacg cagattgcag gtattggtca tctctagtgt
     4141 cagttttttg ggaatggctt cctcctccca ttgttgccat aactgttcct caccacgcat
     4201 tccggaaggt gtcctcgctt ccaggggacc cggaagcagg atgccgtttc cgttaagacg
     4261 ggcgatgaaa gcggcggcac cggaagggaa ggaggccggg caaggctctc cttcagtagt
     4321 tccatacgac gccatgtatt cacagacaag gttcttctca gtctcggaca gcgacaggaa
     4381 catgttcgct ctgccgtcat ataaataaca ggacgccccg tcaactgtga acaatttgac
     4441 caggggaaac ttattcattt tttgtttttc catagtggct aatctgttta caaagcatcg
     4501 tacaatgcag gaatcaatcc cagtctcttg accaccagtt gaaatctaca ccgaaagcgg
     4561 agtcatcggt atagcaaccg cagtagcata cacactcttc agacccggcg gctttcccgc
     4621 ctttcgtctt ttccaactgt tccgaagtga ccgtcttgtc tttcaggtct tccggacgga
     4681 tacctagttt ggcaatctgt tttcccatag cctttaaaat tggagttagt tcatacttgc
     4741 aacatttcac tcctttaaaa tattgcaatg ctgatatagc ttaccggtta ttcaaatccc
     4801 atagccgcga tactgacatt cgtttttcct gataaatcac ggctctataa ttcatttttg
     4861 caatctgtct caaatataca gattccattc aagaacacaa tatttttctt aaaaaaaaat
     4921 aggataaacg taatgaatta tttttcatta acatcttagc ttctatatga ttccggaaag
     4981 gaatccgtca ccaaccgaac aatcaaaata tatggacatt taaagaacca ggcatgacaa
     5041 aggaaccggg aacaggcaac catgatagcg gtacaaggca ggtgcttcca aagcctcttc
     5101 ctttcgtttc ggactgactg ccgccgggtt cagagaaact gtctccaggc atgttccggc
     5161 tgtccttcat ttttctttct tttcaccggc aatacatttc catcattgcc gatatattgg
     5221 tccatcagct cctcaatcag gcttttattc tccacctggg atgaaatcag ttcaaacata
     5281 tccgtttccc ggatggcatg caaggtgacg gcagcccggc gttttttctc ctcgttcatt
     5341 tgggcgccat ccagattaag cagcacatcg ccggcattga gcaggtcatc ggacgtgatt
     5401 accggagtga taccttccgt gccgggagcc tgttcgtcca gcctttcctg ttcctctttc
     5461 aacagtctca tctcttccag agggagcccg cactccacct cattctccgg caccgcctct
     5521 tcctctccga gataatcgtt cccggtttcc aacggctggc tcatgtaggg ggcggcaaac
     5581 gtacccgcgt tttcgtccag atagacaaat cgggtagccc ccatcacatc acccggtcct
     5641 gtaccgcacg atgttccctc ttcctccttc tcctttttcc cgggggtata gagcagcccg
     5701 caaatcttac ggatccgttt tttctgattc cataacttgt ataacaagta gccggcacag
     5761 ccgatcctta ctgacaaata aactatttct tccattccaa agggttttga tttgcttcct
     5821 ggttatatat ttcattgata acatcctgat atctttccag gtggtcggac aggacactgc
     5881 ctaaaaacat gggaactgac atatccggcg caatgacagg caataatttg gcaacagtcc
     5941 tgtacaaagc atcgtgaata taggtctgcc ttcttgaacc ggacagtctc tctttcagaa
     6001 accgttgccg gtattcatcc gggccggacg cctcatccgt ggattttctt atctgctgtt
     6061 tgggagaacc ggcggagttc ttctcctgct tctcctggga aggggcaggc cggcttattg
     6121 tttccggagc ctcagcggga gaaaccattt tgtccaatgc tgttacatcc ccggccatca
     6181 tacgtttcaa tgcctcctca tccacctggt aatccgttct tcttttggta gccatgattg
     6241 ttcttattga agtttcagta tggtttctat ctctgttgcc agcaagtcca aattgctgcc
     6301 cctcaatgcg gaaggggttg gagggaacaa ggtgctgcga aagaaaaatc ccttcatccc
     6361 gaagtcttta ttgtagcgct ccgcactggg aatgacggtt tccatcgccg gcaatttcag
     6421 cgagcggaaa atttcagtgt agctgttata caggtctttg gatacacgtt tgtccatccg
     6481 gttccagaac atatagatgc cacgcaaggg cacatcctta tgacggtgca tgtattcccg
     6541 gatggcaagg acaaaagcca tgctgctccg cataaccatt ctttcctgtg tgacgggagt
     6601 gaatacatag tccatattga ttacggaccg gaagacaccg ggcacattca cagttccggg
     6661 aaggtcaaaa aggacaaggt catagtccag tcccgatttc tcaaggaaac ggccggcagt
     6721 ttcccgggct tcctccggag tggagttcag gatgctgtag gctttcctcc cgcttgtccc
     6781 gaactgttcc accagctggt tttgcaaatg cacgttcttt tcaatggtcc ccacttccca
     6841 gtcccgcatg gtgctgatac tgtgctgcgg ataatcgcaa tccaccacaa gcacgttata
     6901 tcccttcagg taatggaagt aactggcgag caagacggtg aacgtggatt ttcccacacc
     6961 gcccttctgg ttgctcaaag cgacaaataa aggttccttc ttcataggct tgaatttaga
     7021 gtgtataatt tggtttcata tctgtccggt tctgtttttt ctgtttcatt acatgacaac
     7081 gcatctgtcg gtatatggca atgacgcact gcctgcccgc ttgcatgaat acattgcgta
     7141 ccctattgca ccaatgtatt gccggttacc ggagggtatt gccatataag gtacattgca
     7201 ttcatgtgat acggagtcca atgcaacccg tactgtattg cattcatgca atgtaatccg
     7261 ccatgcagga tcaccgtgca acatgtatgg caatgtacct acagggatga tattgcatcc
     7321 gtgccatgta ccgcctgtgg caggcaagca atacacctta caggacaatg ttccaatgta
     7381 tgccctcatg cactgtgcca aaagtagcgg ctatttttga gacttccgcc aacatttccc
     7441 cggcctgaca tcagatgtcg tcagatgtca tcaaacgtca tataaaacac tatttaccag
     7501 ccagttaaca ctctctaatt ttgcaaaatc aaaatccgtc aatggagagg aacatgcttc
     7561 atcggaccac agcacgccgt gaacgtcgcg cagcaatccg acgaaggagg attctctgtt
     7621 caaacgaaca gagcaagttg tgtccttgtc cgacaaaaag tcttttgtcc gacaaggacc
     7681 aacttgcccg cccccgggcg ggggaatccg ctccaaagtc gcggattctg gaaaagaaaa
     7741 aaagtacaaa ccaacaatct catgcattat ggagaaaaca acagggacaa ggacaggcag
     7801 gaaacccaag aatgacccgg cggaccgcaa gtacagcttc cgcctgaacg ccgaggagaa
     7861 caccagattt gaaaggctgc tggcggattc cggagccagg gaccgcacgc tgttcatcaa
     7921 gaaatccatc ttttcgggac agataaaggt agtgagaatc gacaaggcga ccatagatta
     7981 ctacatcaag ctgaccgaat tccacaagca gttccaggca ataggaaaca actacaacca
     8041 ggtggtgcgt gccttgaaga acaatttcgg ggagaaacgg gcgatgtcac tgctctacag
     8101 gctggagaag ctgagcgtcg agctgatgct tctctgcaag aaaatcacgg cactcaccca
     8161 ggaatacgag cggaaatggt tgcaaagata agtcatggcg ccagcctgta cggggcactg
     8221 gcctacaacc ataacaaggt ggcgaccggg gcggcgggga ttctttcggg gaaccgcatg
     8281 atttccgacc ggctgggatt gccaagtgaa gacatgcgcc tggcattgct ctctttcgag
     8341 aactacctgc tggcaaaccg caacacggag aagcccgtcc tgcatatctc gctctccccg
     8401 gcaccggaag acaggctgac cgacgaccaa ctggcggaac tggccgaccg gtatatgcgg
     8461 aagatgggct atggagacca gccttatatc gcctacaaac atgccgacac ccacaatgcc
     8521 cacatccata tcgtcagtgt ctgtgtggac gaacaaggga aaaagatcag tgactcctac
     8581 gagcaccgcc gttccatgac cgcctgccgg gagctggaag cggacttcgg cctgcgcaac
     8641 ggtgcggaca cggagaaacg gaatccgaaa gcggaactga aaaaagtgga tgcttccctg
     8701 ggggatgtcc gccatcaaat cggcaacacc ctcaaggcgg tgctggaaag ttaccgtttc
     8761 caaaccttcg gggagtatag cgccctgctt tccaccctca atatcgaggc gaaacaggtc
     8821 aggggggaat accacggcgt gccttacacc ggcattgtct atgccgccac ggatgatgcc
     8881 ggcaaggtgg tcagccctcc gttcaagagc tcccgctttg gaaaacgttt tggcaacgaa
     8941 cagctggaaa aacggatgct tctcaacctg aaggcgctca aggaagggaa atgggctccc
     9001 tccatacagg cggacattgc ccacgccttg caacaggctg actcacggca acggtttgtg
     9061 gaactgctcg gacagaaacg tatcggcgtg gtgttccggg agaatgaaca gggacgcatc
     9121 tacggcgtca ccttcattga ccacgaccgc agggaggtgt tcaacggctc acgcatgggc
     9181 aaggagtttt ccgcaaacgt gttcaacgac tatttcaggt ggctggacgg catctccgaa
     9241 aacgaccgga acggacatac ggcagtggag ctctggcagc atcaccggca caaggcgggc
     9301 ccggaaagcg cgctcgagca ggcggcgggt atcctctccc tggaaaccaa cccaagggat
     9361 taccaggagg aggctttcgc acgccgtatg aaaaagagga agaaagccaa acgcaaatcg
     9421 cgcggcattt aaacggaaga caattttcaa aaaccattta tccccatccc tatgcaacag
     9481 gaagacgatt tgagggcact tgccaaaatc atggaatttg gcagggcagt gagtattttt
     9541 cttttggtgg tgcacgtcta tgtgtactgc tatccgagta tcaccgcatg gaacctgaac
     9601 ctggaggtga cagaccggat tctggtgaat ttcaacaaca cgaccggcat tttcaactgc
     9661 atcctctgga ccaagctgct ggctgtgacc ttactggcaa tatcctgcct gggaacacat
     9721 ggagtcaagg gtgaaaaaat cacctggccc aaaatctatg cggcgctggt agccggatgc
     9781 gtgctgttct ttctgaactg gtggctgctt gacctgtccc tgccgcacat gacaagcacc
     9841 atactgtacg ttataacact taccgcaggt tacctcggcc tgctgatggc agggttgtgg
     9901 atgagccggc tttacaggca taacctgatg ggcgatgtgt tcaatatcga aaacgaatcc
     9961 ttccagcagg aaacccggtt gttggagaac gagtattccg tcaacctgcc caccagcttc
    10021 cgctttcagg agaaacagca tgacggatgg atcaacgtgg taaatccctt ccgtgccacc
    10081 atcgtgctgg gaacgcccgg atcgggcaag tcgtatgccg tggtaaacaa ctacatacgc
    10141 cagatgattt ccaaaggata cagttgttac atctacgact acaagttcga cgacctctcc
    10201 accatcgctt acaacacgtt gttgaacaac atggacaagt acaaggtcaa gccccggttc
    10261 tatgtcatca atttcgacga tccgcgcagg tcacaccgct gcaatcccat caatccggaa
    10321 ttcatgacgg atatctccga cgcgtatgag gcgagttaca cgataatgct caacctcaat
    10381 cgcacctgga ttgaaaagca gggcgatttc ttcgtggagt cacccatcat tctgcttgcc
    10441 gcaattatct ggtatttaaa aatttacaaa aacggcattt attgttcctt tccgcacgcg
    10501 gtggagctgc tcaacaagcc ttattcggat ttgtttacca tcctgacctc gtatccggag
    10561 ctggaaaact acctttcccc cttcatggat gcctggaaag ggggcgccca ggaccagctc
    10621 cagggccaga tcgcttcggc aaaaatcccc cttacgcgca tgatttcccc acagttgtat
    10681 tgggtgatga caggtaatga tttttcgttg gacataaaca acccgaaaga gcccaagctg
    10741 ctttgcgtgg gcaacaatcc ggacaggcag aacatctact cggcggcgct tggactatac
    10801 aattcccgca tcgtcaaact catcaacaag aaagggcagc tcaagagtac tgtcatcata
    10861 gacgagctgc cgaccatcta tttccgtgga ttggacaacc tcatcgctac cgcccgaagc
    10921 aacaaggtgg cggtctgtct cggctttcag gatttcagcc agttgaaccg cgattacggt
    10981 gaaaaagagt caaaggtcat ccaaaacacg gtaggcaata ttttcagcgg tcaggtggtt
    11041 ggagaaaccg cgaagacgct ttccgaacgt ttcggcaaag tgctccagca gcggcagtcc
    11101 gtttccatca accgccagga tgtatccacc tccatcagca cacagcttga ctcgctcatc
    11161 ccggcttcca agattgccaa cctgtcccaa ggcacatttg tcggagccgt ttccgacaat
    11221 tttggcgaaa agatagacca gaaaatattc catgctgaaa tcattgtgga ccatgccaaa
    11281 gtcagcgcgg aagaaaaggc ttaccggaaa atccctgtca tcaacgagtt caaggacaag
    11341 gatggaaacg acatcatgat gcagcagata cagcgcaact atgaccggat taaattggat
    11401 gcccaggcaa tcatcaatga ggaaatgaat cgaatcaaaa gtgatccgga gttatgcaag
    11461 cgattggggt tggatgatga aaaatcatca aagaagaaag aatgattcat cttcccttaa
    11521 atctccatga agtgtgtggg aaacgatata aaagcttccc tcacactatt attgctttgt
    11581 atgataatgc ctatatgaca ggggtttgac aatacatttc aggatagaca atcaagtaat
    11641 cttccgtaaa caggctttta tcaaaaaagc aaaattgaat agcaggacat acatctataa
    11701 atgccttgtt ccggttgttg aatctgaaca gagaagattg gatgtacgag ttcggcaaag
    11761 tacacaaagg attgaccctg atagctttgt agagagtcga gaactgggta aattgtttca
    11821 ggtatgcaat aatttcagga acgtaaacag ttgacttgtg ccacttttta gtgatgattt
    11881 ccgaacatct tttcatctct atcagatgct ctggtcttcc aaccaaatca aatacctttt
    11941 ctaatttgtc atcacaagct gactggcaga ttatataccc actgtcctta tagcaaagat
    12001 ttccccacca atgggcgagc tctataattg tatcccagaa ataatagcct tctccaagcc
    12061 atgcgttttt attcgtacaa atgaacggcc catgttgttc cacatagtca gggttctctc
    12121 tgtcttcaac ggtctgatat atgattctgt tcattgaagg cttcttactt taagaccgtg
    12181 tttctcctta gttcacgttc taacaacgat acattcagtg tgggtatcat tatcggagct
    12241 acgtttgctt gtaatgttat agtacttaca aaagcacgta cataagggaa aatgatagca
    12301 atgctgttcg cataaaaata agaagggatg gtatcggtct gtaccatgtc cccaaaagaa
    12361 aagacggctt taagtttgat gtttataacc tcaaagtcag tattttcttt cttatatgaa
    12421 gccttgaata ccagatttaa tacatattgt ctttctctct gaaaatagat gccggatggt
    12481 tctattttca aatcgaagat acattggggt ggaatattct ccaagtcaag cattactttg
    12541 actacggagt aattttttag tgaaaaaacg gcttgctgca ttatgatgta ttttaatgtt
    12601 ttatactgcc ataggtaaat atgaatcaga cccgaaatcc tgggatatag gggattctac
    12661 attcactctg gatgttggat ggcttccgta gatgccatct acaatttcat tgtgtaaggc
    12721 attcttttca cattcttcaa taaattgatt gatttcaggt ccataagcat acttgctgtg
    12781 tatagcttcc caatcttttt gtaattgttc ttctggggtg ttgctgaaat attccaaaag
    12841 ttcttctgat aaacgtttca tctcaatcat ttattaaata tatactattg caaatatagt
    12901 aatttattct attggtatgg ctaaagtcat cacttttaat accaatagca acaatcaatt
    12961 cactatcata acaatattta agacaaagtt cttaagcaat attactatta cacgcagcat
    13021 cgttagttct ttcatctact tcccaaactc cacaacaacc tccacaacct ctccacgcac
    13081 cctccgcaca tccaacaccc gtgcaggaat cccatgtccg aagcagcatt ggataaactc
    13141 catcccgata aacactccca tatctgagtt tcctgcatta tgtttgtcct tattgctaaa
    13201 cgtgacggtt cctttcatct cctcattcct tcgtttacgg tattgcatct ccttttggaa
    13261 catcatagta acttcgcctc tgacgatttg cacctgttgc cctccggttt gtaagaattt
    13321 caaataactc tccagcagat cttctggaca tccgctatga gacaacacgt tttttacgct
    13381 atgtatctga atcaaatttt ccatcatttt ttatttggcg ataataatct ttttatcctt
    13441 aacaacaagc gtatccttcc caccattatt catcaaatta acattcttca agtctatccg
    13501 gctattagaa atggagaact cctgatgaat cgtatcattc cgcaaaaagt gaatgtcctg
    13561 cttatacagg ttcggaatgg aaaagaacag ggtgataatc ccgatgaaac acagcaccat
    13621 caataccgta aaggtcacaa accaccgctg atatttacgg tcttccacaa ccttcacttc
    13681 aataggcaat ggagattcct gatagctcac ccgtttctgt ttccatgtta ctctgcaacg
    13741 taggttcgga aattcatgca ggctgaacaa ctctggcagt tcctgcaaga aatgcaggta
    13801 ttgtttggtt tccatcaaca cttccaactc catggttaca cgaataacac ttcgtttcat
    13861 tatcttgggt tttcccgatg cacctgtagg tttggctaca ttgatgggac ggatatccga
    13921 agccccatta tccatgctca tggcaagttc cactccggta ctacccaaag agggagcatc
    13981 cgtaggatga ttgccgaaag atgaagaact atttcgttct ccttccatgc cctcatattc
    14041 tgctatcaag tccgctatct cacgtacttc ggtcacggtt acgttctttg tctctgcgtc
    14101 ggcaaaagtt tccactttaa ctttgactgt atcagttaga aaggctctta tcttgtcttc
    14161 gcttttctta tggataaggt agctgggata cttttgggtg aagttccgag ctacgttttc
    14221 cacataatct ctcgtataat tataatcact ttcaatacga agaaaaaaaa cgacagataa
    14281 attaaactga tttaataata ttcctcgatc cataactata ttttatttct gctcaatagg
    14341 taaaatgaaa tgattgccat tatctttact ccaaggagta taaatccaaa attgaatgct
    14401 atcatcttga agcaataaat taataatttc aggatatttt ttcttaaact cttgaata
//
