LOCUS       gnlProkkaOGEAPAED_50    9631 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OGEAPAED_50.
ACCESSION   gnlProkkaOGEAPAED_50
VERSION     gnlProkkaOGEAPAED_50
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 08:06:18
            Original ID  :: gnl|Prokka|OGEAPAED_50
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 9631
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..1164)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg50_1"
                     /sec_met_domain="Polysacc_synt (E-value: 5.2e-32, bitscore:
                     100.4, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIY"
     protocluster    1..9631
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[1506:5820]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1507..5820
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..9631
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..9631
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(1367..1510)
                     /locus_tag="ctg50_2"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             complement(1507..2628)
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg50_3_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_3"
                     /sec_met_domain="Aminotran_5 (E-value: 9.5e-32, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        complement(1531..2538)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg50_3_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg50_3_Aminotran_5.1"
                     /locus_tag="ctg50_3"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             complement(2638..3762)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_4"
                     /sec_met_domain="TPP_enzyme_N (E-value: 6.7e-21, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.8e-21, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             complement(3779..5080)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_5"
                     /sec_met_domain="CTP_transf_like (E-value: 1.2e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.3e-121, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.4e-63, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             complement(5101..5820)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg50_6"
                     /sec_met_domain="NTP_transf_3 (E-value: 1e-16, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             complement(5884..7032)
                     /locus_tag="ctg50_7"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             complement(7043..9454)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 32.3;
                     E-value: 7e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg50_8"
                     /sec_met_domain="Poly_export (E-value: 6.7e-19, bitscore:
                     56.9, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIQRLFSILLFCLMLGSGSLMAQSMSDSQVLEYVKDGIRQGKEQ
                     KQLASELARKGVTKEQAMRVKQLYEQQNNVNTSKSTGTDINESRLREETKKNTSDMLED
                     HPTTQDLARGDQVFGRNIFNTRNLTFEPSVNLATPANYRLGPGDEVIIDIWGASQNTIR
                     QQISPEGTINIQKIGPVNLSGMTVSAANDYLKNALNKIYNGLNNTTDPTSDIRLTLGNI
                     RTIQINVMGEVVQPGTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVY
                     EFIMKGNTQDDIRLQEGDVVIVPAYDVLVKISGKVKRPMRFEMKKDENLATLIKYAGGF
                     EADAYTRSLRVVRQNGEEYEVNTVKDIDYNIYKMRNGDVVTAEAILNRFTNKLEIRGAV
                     YRPGIYQLSGKLNTIRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGT
                     SPNLALMKNDILYIPSIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKEA
                     ASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRRSPG
                     YQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKK
                     RMGDVIRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIP
                     KNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKG
                     SGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
ORIGIN
        1 gtaaataact ctaccccaac acatcacctc aagcccaaat ggaattgaca caaaaagaat
       61 gaatatagca atcgtctttt ttattatttc aagacgtaac gacagatcag atcttccttt
      121 aacccataat aaattcaaat taatttggct caaatgatca aacatccaat ccaaacataa
      181 tatctgtaaa agaataacaa ccccagacca tttatctgtt aacaatagac taataatagg
      241 attagccaaa acaagtaaac ctaccattaa aggaaaaatt atatatgagg ataatctgat
      301 ataatttcga tatgcgtttg ttaaacattt atcatcatct tgaatggaac ttaaaatagg
      361 atacgctact ctagaaacta aagcatttaa attattggaa ggaaaaatag caaattgttc
      421 tgctcttgta tagtaaccaa gctctacaac agaaaacttt tttcctatta caatggtata
      481 cagattacga tatactgtat tgataagact tgagatcaat aatttagatc cgaaattgaa
      541 taatctttca aaagaacttt tggagaaagt atgtaaaggt ttccaatgaa ctaaacagta
      601 aaacaaaatt gtcaaaatta tactatttaa gagagtttgc caaactaaag cccaaacccc
      661 gcaaccgaca taagccatcc atattccaat cacgcctgat ataaaagctg cacctaatga
      721 aattttagat tgagttttaa agtttacaga aataattaat ttcgttctgt gaatagccga
      781 taaagcattt attatcaacg acaatgctat aaaacgaatt acaagaacta aagtcggcat
      841 attataaaag tctgcaatca aagaagccga aaaaaacaat ataccataga ataatactgc
      901 gacaagaata ttaaaataaa agacagtggc aaaatcctct tcagttctat cttttttctg
      961 gattaaagca tttgtaaaac cgctatctat aaatacttga gcgacttgaa gaaaaatagc
     1021 taacatcccg atcataccat aatccgatgg tagtaacaaa cgagctaata ttatttgaat
     1081 tataaactgt actccttgta aagagaaacg ttctatagcg ctccacatta ttcctgatac
     1141 agttttctgc tttagatttt ccattactta aatacagtat aaaaacaact acatttaccg
     1201 atatcaatta tatttttcca atattctcac taattggtta ttatcttctt cgccccttac
     1261 cgcaattcta atatggtctc tcccactaaa agcaaattac cctacacaaa cattatctcc
     1321 tataactacc gatgcctttt tataagaata aagaactcct aatgcatcac ctcaaattaa
     1381 tattgccata tttgcctact aagcgaaagc tacgaatagg cactccagaa ataacacttt
     1441 ccggatggaa gtgtatacca cgaagggaaa aataaaaatg acgaatcttc aataatattt
     1501 ctgcaatcat gacatcggta atgtgacgtt ataatgattt aatgcagctt ttagtacttt
     1561 aaagaagttc tcaatatcat ctacttctat ctctcctaaa gcacagattc taaaagtatc
     1621 ctcagttgat atcttacctg gataaatcgt aaatccacgc tcataacaat aatcatgtat
     1681 tttctcaaaa tcccagttgg gatcttctgg gtattgaact gagacaacca gtcctgactg
     1741 ccattcacgc tttattacac ttttaagacc aatttcattt atacctgaat gaatagcctc
     1801 aaaaactctt ttgtgacggg caaacttagc ttcttcaccc acttcaaaat attcatttaa
     1861 tgcctgacga gtggcgtaaa tagtttgtac cggtggagta aaatgcattt cacctgttct
     1921 ctcaaaattc tcatactgca aataaagatt acaatagtaa gaacgcttgg gatatttttt
     1981 tgaaaactta atctgttcct cattgcctat aataaaagaa agacctgtca tcgcttgaag
     2041 tcctttttga gcagatgcca tacaaaaatc cacattatct ttctctatat caaaaggaat
     2101 catgcccaaa gaagaagtag tatcgacgac aaatttagcc tgatatttat gagctatagc
     2161 gcccatctcg cgaatagggt tcagaattcc tgtacccgtc tcgtgatgag tagtataaac
     2221 catagctata tcaggatttt cttgcaacac attttccacc accgataaat caggacgttc
     2281 gtaaacggaa aattccaaat taatatgagg caaaccataa tattgacaca cttctacagc
     2341 acgggtacta tatgccccat tattcactat aagcaccctt ttgtcttcag gaagaagaga
     2401 atttagacat atatcaatat tgatggttcc tgagccacaa aataatacag cggtatgttt
     2461 ttccaaattc ccatgagcaa ctctgaccaa atcgtcccga agttgtttca tcatacctgc
     2521 gaattctttc tcgcgaggac aaatatccgg aacaacttgt gccattttta cactgtcagt
     2581 agtagtggca ggcccaggat ttaataatat ttttctttct attttcatcg aatatattta
     2641 ttttaaaaaa tccataaaat gctccttatt ctctatagga gtagtcgtgg gacgtcccaa
     2701 attctcccga gaatctattt taacctttat ttccaacaaa acaggaccac ataactttgg
     2761 aagctgcttc attgcttctt caatttcaac ttttgtacaa acagtataag tatgcttata
     2821 tccgctcccc cggacaatag ccggaatatc taaactaaat cctaaagtag gctgtcctcc
     2881 tacagactcg tgagcaccat tgttaaacaa aatatgataa tagtttttag gagataaatc
     2941 gccaatgtta ctaattgccc ctaaatgcat aataaatgct ccatcaccat ccaagcaata
     3001 aacaggtcta tcttgctttg ctatagcaat acccaaagag attgatgaac tatgtcccat
     3061 agagcctacc gtgagaaaat catgttcatg accttgctct ttcatttctc gatattcaaa
     3121 taactcacga gaaagcttgc cagtagtaga aacgaccact gaattttcag gcagataatc
     3181 cacaactatt tgcaaagcat cctcacgaga taaaggataa ttacatccga actctttttg
     3241 aagtttatat ttgccaaaaa catctttccg aataattatt gcatgaggaa tattcttagt
     3301 ttttgctgat tgtatgatat catggagctg aataaatgca tcattctcat ttgaatcaag
     3361 aattatataa ggaatccgca ttgctttcaa caaatctaaa gttacctcac cctgtttttt
     3421 atgctgaggt tcatcttttg ttcccggttc accacgccag ccaatcatca aaagcattgg
     3481 aaaactgtat acttgttcat ctgcaagaga cagcagagga ttaacagtat tacccaagcc
     3541 ggaattttgc atataaacca caggaacctt acctgatgcc atataataac ctgaagcaat
     3601 tcctacagcc gcaccttcat tagcagctat gatatgtttc tcacgtgaag tatggtctgt
     3661 gatataggca caaatatttt ttagtaatga gtctggaact cctgtaaaaa aatcaacgtc
     3721 atgactcaga aacgtttcat aaactttttc tacgcttaac ataatgatat tcctcttttt
     3781 atttagtacc tggaatcagt tccaatattt cttttatggg catacacagt tcgcgcacct
     3841 ctaaagcacg ttcattctct aatattatct ttgcgacatt catcatagca ggataagcgg
     3901 cacgaagcat atgattagca taaataatta tattcacacc ccaatcacac aattcagact
     3961 cataaatatg atcatatgta gtaggcacaa ccacgatagg tacatgagca tactgttttc
     4021 gaaacgccaa acaaaattct tttatatctt cacccgactt atttttgcta tgtatcataa
     4081 taccgtccgc tcccgcttgg acatatgcaa aagctctctc taaagcatca cttaccggct
     4141 ttcccgctat aaggctctca atacgagcga taatcataaa atcatcagta atctgagatg
     4201 cctttcctgc tttgatctta ttacagaaac cttcgattgt atcttgagtt tgaataacat
     4261 ctgtaccaaa caatgaattc ttttttaatc caactttatc ttcaattatt atagctgaaa
     4321 ttccatgacg ttctaaagtg cgtactgtaa atacgaaatg ttcaatttta ccacctgtat
     4381 ctccatcaaa aataataggt ttagtagtac actccagaat attattcaaa tcttgcaatc
     4441 gggtagttaa atcaaccgcc tcaatatcag gtttaccttt actggttgaa tccgtaaggc
     4501 tactagacca cattccgtca aatacttccc tcttatcccc ttttaatatt tcctgatttt
     4561 caattatcaa gccacatagt ccatcatgag cttccaaaat acgaactacg ggtttggcat
     4621 ttatcaaacg acgaagtgat tttaaacgta catcaggggt tgtacctata gccttaatat
     4681 ctttatccaa agaagatgaa ttaattccca aagtatatgg aatttcgata acctttcctc
     4741 cctgttcatt catcacttca aatacgcgca cacgttcttc acgtaaaggc ccggttttcc
     4801 agtcgtcacc atgaattata tagtcaggtt taatgcgttt gagattctca acatagctcc
     4861 attcttcttg aggaacaact ttacatacgc ctttaatatt ctgaactacc tcttttcgtt
     4921 gttcataggt cagataagga aggcgtttat gctccgcaat agctttatct gtaagaagac
     4981 caattataac atcaccgtat ttagtagcct cattaataat gcggataagt cctggatgca
     5041 taatatccgc agtcatccca atataaactg tcttactcat aatttgatat attattttaa
     5101 ttaacaatac ggaacaatat atttctctgc atattccaaa tctgatatgt catcgatttc
     5161 ataccatttc agcccttcta ctttatgcac ataaacagga gattgagaac aagatattcg
     5221 tagtaattca tactcatatc ccaaattggg ttgttcatca acaatactcg cataatcagc
     5281 acacattatt ttgtaaaagg aaccggatag tttatggatg ccgaccaatt cgcctttagc
     5341 gtttagttta ttcttattga cagaacatga agaaaggcga aaattatcat catgttccac
     5401 ataatactga tcttgaaact ttgtcactgg agttattagc attgcatctg ccgcaggaca
     5461 ctccaataag ctcattattg cttgtttctc aaaaatcaaa tctgactcta acaataaaaa
     5521 atcatcattg cccagaatct cccgcgtatt atataaagta tacatactat ttgtttcagc
     5581 ataacgagga ctaaaacagg tttcaagcat aggatagtct gtcttcaatt cttcataaac
     5641 ttcttgttta tatcctgtac cgattacaat tcgctcaatg tcacatgata acaaagtatc
     5701 aatagaacga actatcattg gaatacctcc cactttgacg aaccctttag gtatcaattc
     5761 tgtatattgg ccaaaacggg ttcccatgcc cgcagccatt atcatagctg tacgtatcat
     5821 tcgtttaata atatagtaag tgaatttaat tgatgtaaga atgttgtaaa cgacgtttta
     5881 gcatcattta tcctgttcta tctccttatt tttcagttct tttctcaagc tagccagcag
     5941 acttttgcca aaaaacaccc acacgagagt accagatacg gacaggaaca caaataataa
     6001 aatataaatt ttgagtccca tacctgaagg tttcaaaggt acaacggcag gctcaactac
     6061 tgcaaagact ggcttttcct cctgtacttt ggctctggat acctgcaact gattagcaac
     6121 ctgactatat atctgataag ccaaactcat gtcgttctgt aaacgctcct gctcagcacg
     6181 tacactttga agaaccacat tatcatgggc gtctacataa tccgcatatt ttctttgagc
     6241 agcataatat tcctgctgac gttctttaaa caaccgttcc aaatacgcac agtcttcttt
     6301 tacttttgaa gttcgatacc caataatata ttcctgtaat ttatgaacga cagaatctgc
     6361 tataaccgca gtgatctgcg gattttgtaa ggtgaccgta atgctcgtta tggcggtttt
     6421 cttatcaatg gatgcactaa tcttcttttt aagaaaatta atcttctcat ttacttcttt
     6481 cgtcaattcg atagttcctt gccgccctcc actggcagga accgtatctt ctccgaataa
     6541 tgatttaact cctcctatta ctatgcccgg aaaacctata agataatccc accaaggaga
     6601 tgactcttca tcgagataag accccaaagt cattttatca tcctttttag aaacggagac
     6661 ttccatttct aaaagttcca ataaaaaagg agttgaagaa acaatatctg ctgaaagaga
     6721 agcgttcaag gcatctgtgc tttcccctat tagagcccca tctcccaaaa acgaggcagc
     6781 aagtccggct aaaccattac ttcccttcgc attacccatt tcaggagaaa gggtaacctt
     6841 tactgtatat tgcttgggaa tgctcaatgc caccactata gcaattatta ctcccactcc
     6901 agcagctttg catagtactc cacgaacagt aataatctta taaaaaatag ccatcaagtc
     6961 tatttccatt tcatcatctt tccttttatc cacttcagaa aacggttctt gataagattg
     7021 cttttcaatc ataataggtc atttatttct ttatcaaatt agcaatagaa gcaatcatca
     7081 ttcccaaaga actgaaggaa gtagcataac ctaaaatatt agctatgttc cctttcttct
     7141 tagccttacc aggcacaata atctcacacc ccggctcaat ctgtttctta ccactaccct
     7201 taaccttcgt cacctgacca ttcatgtaaa caatgaactt cttactcttc cttgcattat
     7261 cagaacagcc accggcctga ttcaggtaat aatccacatt ctttcccttc atataagaaa
     7321 ccgtattcgg aaccatgaca gcaccattga tagttacagt attagtattc ttaggtatgg
     7381 agatcacatc accttcacgt aagacaagat cggcattact tttaggattg ctcaaggctt
     7441 tttccaaatc tattccaacc gtaaaagtat cttcaacacg aatacccaaa gagtcaatca
     7501 tggcttcgcc caattgcctg ctcataaggc gaattacatc acccatacgt ttcttttcac
     7561 tagcgttagc cacacgggtc agtttcgcac cacgcagata ggcataattg gtcggaccgc
     7621 cggctttatt cactaaatcg gaaagacgtt cctcacggct ggtcatggcg taatttcctc
     7681 cgaaaaggat ttcaccttca atggctacat tctgttgtgc ctgatagccc ggactgcgac
     7741 ggacataaac ctgatcataa ggctcaagga taaaaccggg ctgaccatct attacaaaac
     7801 catcctttaa agagaaggta tacatctgac caatcgtatc attatccgca gtactacgag
     7861 gattcttgat tcgtctcgat atatcaatac ggacagtaga ggcggcttct ttcaagccac
     7921 cggcctgaat gatcagatcc tcaagtgtca tgttatccgc ataaggatag gaatcagggt
     7981 gggcaacctc accgtgaact gtgacattac cccggtcttc caggtcatgg atacttggaa
     8041 tgtagaggat gtcattcttc attagggcaa ggtttgggga agtgccgtcc atgatagact
     8101 taatgtctat ctgaacaact tcactggtca ggtcttcacg ctggcgatag aggacggcac
     8161 gattcaggaa agcgtcaccg gtcagaccct gagcttcatg gacaagttcg cggatcgtgt
     8221 tcagtttacc gctgagctgg tagataccgg gacgatagac agcgccacgg atttccagtt
     8281 tgtttgtgaa gcggttaagg atggcttcgg cggttactac gtcaccgtta cgcattttat
     8341 aaatgttgta atctatatct ttgactgtgt tgacttcgta ttcctcacca ttctgacgga
     8401 caacacgtaa tgaacgggtg taggcatcag cttcaaagcc gccggcatat ttaatgagag
     8461 tagcaaggtt ctcgtctttc ttcatttcaa aacgcatagg acgttttacc ttgccgctaa
     8521 tctttaccaa tacatcatag gcaggaacaa tcacaacgtc accttcctgt aggcggatgt
     8581 catcctgtgt gttgcctttc ataatgaatt cgtagacgtc gatggtggca atattctttc
     8641 cgttgcgtac caactgaacg tttcggaggc taccgatatc actcacaccg cctgcacgat
     8701 aaagcgcatg gaagacggta gagaaggaag aaagggcgta ggtaccgggc tgtacgactt
     8761 ctcccatcac attaatctga atagtacgga tattacctaa cgtcagacgg atgtcggaag
     8821 taggatcggt agtattattc agaccgttat atattttatt cagggcgttc ttcagatagt
     8881 cattggcggc agagactgtc ataccgctaa ggttgacagg gccgatcttc tgaatgttga
     8941 tagtaccttc aggagagatt tgctggcgga tcgtgttctg gctcgcaccc cagatatcaa
     9001 tgatgacttc atcaccggga ccaagacggt aattggcagg agtggcaagg ttgacactag
     9061 gctcgaacgt caggttgcgg gtattgaaga tgttacgtcc gaagacctga tcaccacggg
     9121 caaggtcctg agtagtcgga tgatcctcca gcatatcgga agtattcttc ttagtctctt
     9181 cacgcaggcg ggattcgttg atgtccgtgc ccgttgattt cgaggtattt acattgttct
     9241 gctgctcgta tagctgcttc acacgcattg cctgttcttt ggttacaccc ttacgggcta
     9301 gttcggaagc aagctgcttc tgttccttgc cttggcggat gccgtctttt acatattcca
     9361 gtacctgtga gtcactcatg gactgagcca taagcgagcc acttcccagc atcaaacaaa
     9421 atagtagaat gctaaaaagt cgttgtattt tcattgacaa ataaaaaagt ttcagttgat
     9481 ttcacacagt tcctgcatcc catgacagac ggcagataac tgttgcttaa gaagagaagg
     9541 gggaagaaca tcgagaagag acagagaacg ggtcaaaaca gcctgttttc tttcttcgtc
     9601 ttccggattg gcgtacatcg acacattata t
//
