LOCUS       c00210_gnlPro..        17338 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OGEAPAED_247.
ACCESSION   c00210_gnlPro..
VERSION     c00210_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 14:24:32
            Original ID  :: gnl|Prokka|OGEAPAED_247
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 17338
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17338
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3824:7338]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3825..7338
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..17338
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..17338
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             3..923
                     /locus_tag="ctg210_1"
                     /transl_table=11
                     /translation="SLFYCHVKDFIYFCCKQEQIKRQHKYMSSICQGTWDCQNCPKAVD
                     NAIIHTTHTRGYHQPARKCEDNFILFLIKGELLVNSQEYAGTMLKAGEFILQAIGSKYE
                     MLAMTECECIYYRFIQPELFCDFRFNHIMKDVPSPLIYSPLKIIPELKYFLDGSKSYLS
                     ESKVCRDLLSLKRKELAFVLSYYYSDYDLASLVHPLSKYTTTFEYFILQNYKKVKTVEE
                     LAQLGGYTVSTLRRIFNNVFHEPVYEWMQARRKEGILDDLNNSEYSISEICYKYGFESL
                     PHFSNFCKKFFGASPRMLRTSKKNV"
     CDS             complement(1178..1465)
                     /locus_tag="ctg210_2"
                     /transl_table=11
                     /translation="MIPVIQRMTHRLTTLICDKRNRRIHKSHVIYKENNNIRALLSYSA
                     NGRCQTTQYTKFLKSSFCSHYIVFMIYILVIVRAIIDFKLRLSSDYTKEY"
     CDS             1679..2797
                     /locus_tag="ctg210_3"
                     /transl_table=11
                     /translation="MPRVLQQAGYKTIHVGKAHFGCMGSEGENPLNIGFDVNIAGSGIG
                     HPGSYYGEWGYGHIKGQKIRAVPDLEKYHGTDTFLSEALTIEANREITKAVEEKRPFYL
                     NMAHYAVHSPFQADKRFLSRYTDPDKNEQARAFATLIEGMDKSLGDIMDQLEKLEIAEN
                     TLILFLGDNGGDAPLGDERGYGSSAPLRGKKGTEFEGGMRVPFIAAWAKPEKKSKVQKN
                     LPIEVGSMQTQLGTIMDIYPTVLSVAGCEVPQNYVIDGFDLKKQLSGKVDKKRPESFLM
                     HFPHAHRGSYFTTYRMGDWKLIYYYLPETPKQPKALLYNLKDDPEERNELSSAHPDKCR
                     EMIQEMSAQLEKEGALYPVDKQGNELKPFVYF"
     CDS             complement(2975..3199)
                     /locus_tag="ctg210_4"
                     /transl_table=11
                     /translation="MTEIMLDKQETLNEIGTKIRKLRESKNLSIQEFADKLEMEYNNVI
                     RIEKGRTNFTIGTLVKIANSLEVNLKDIV"
     CDS             3325..3717
                     /locus_tag="ctg210_5"
                     /transl_table=11
                     /translation="MDTLNLHSNFDNLLYIGRSVLNNTSSHIQKLFFKKEMCIYEYLYK
                     EEVSKGIEIKIDDVVLVCALEHDKCNKSILYFNDVANIARYIHYCNSNFEYKEELNGWI
                     MSDSYLALSISEDDYEKRFAFIQTLL"
     CDS             complement(3825..4580)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg210_6"
                     /sec_met_domain="Fer4_7 (E-value: 2.9e-12, bitscore: 38.5,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 2.1e-25, bitscore: 80.3,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 1.3e-06, bitscore: 20.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKNISFTLKVWRQAGPKAKGAFETYQMKDIPGDTSFLEMLDILN
                     EQLISERKEPVVFDHDCREGICGMCSLYINGHPHGPATGATTCQIYMRRFNDGDTITVE
                     PWRSAGFPVIKDLMVDRTAYDKIMQAGGYVSVRTGAPQDANAILIPKPIADEAMDAASC
                     IGCGACVAACKNGSAMLFVSAKVSQLNLLPQGKPEALRRAKAMLSKMDELGFGNCTNTR
                     ACEAECPKNISISNIARLNRDFIIAKLKD"
     CDS             complement(4617..6596)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 200.6; E-value:
                     1.5e-61)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg210_7"
                     /sec_met_domain="FAD_binding_2 (E-value: 9.8e-62, bitscore:
                     200.6, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 2.2e-36,
                     bitscore: 116.1, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKIDSKIPEGPVAEKWTNYKAHQKLVNPANKRRLDIIVVGTGLA
                     GASAAASLGEMGFRVFNFCIQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRLFYDTVKG
                     GDYRAREANVYRLAEVSNAIIDQCVAQGVPFAREYGGTLDNRSFGGAQVSRTFYAKGQT
                     GQQLLLGAYSALSRQVNVGTVKLFTRYEMQDVVIIDGRARGIIAKNLITGELERFAAHA
                     VVIATGGYGNAYFLSTNAMGCNCTAAISCYRKGAVFANPAYVQIHPTCIPVHGDKQSKL
                     TLMSESLRNDGRIWVPKKKEDAIKLQKGEIKGSDIPEEDRDYYLERRYPAFGNLVPRDV
                     ASRAAKERCDAGFGVNNTGLAVFLDFSEAINRLGIDVVLQRYGNLFDMYEEITDVNPGE
                     LAKEISGVKYYNPMMIYPAIHYTMGGIWVDYELQTTIKGLFAIGECNFSDHGANRLGAS
                     ALMQGLADGYFVLPYTIQNYLADQITVPRFSTDLPEFAEAEKAVQAKIDKFMSIQGKES
                     VDSIHKKLGHIMWEYVGMGRTAEGLKKGIAELKAVRKEFETNLFIPGSKEGMNVELDKA
                     IRLYDFITMGELVAYDALNRNESCGGHFREEYQTEEGEAKRDDENFFYVACWEYQGDDE
                     KAPVLIKEPLVYEAIKVQTRNYKS"
     CDS             complement(6634..7338)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg210_8"
                     /sec_met_domain="SucD_FumR (E-value: 5.2e-131, bitscore:
                     425.5, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWLSNSSVGRKVVMSVTGIALVLFLTFHMAMNLVAIISADGYNMI
                     CEFLGANWYALVATAALAALFIIHIIYAFWLTMQNRTARGSERYAVVDKPKTVEWASQN
                     MLVLGIIVIVGLGLHLFNFWAKMQLPELMHNLDMHADTLTLAYAANGAYHIQQTFSCPV
                     YVVLYLIWLFALWFHLTHGFWSSMQSLGWNNKVWINRWKCISNIYSTIVVLGFALVVVV
                     FFVKSLLCGGAC"
     CDS             complement(7459..8277)
                     /locus_tag="ctg210_9"
                     /transl_table=11
                     /translation="MESTLIHRNLLRGQHIPKDKCTQNCMLFMIEGELLINSDEHPGTT
                     LHEKQFILQAIGSKYEILALTDVSYILFWFNELPLLCENRYREIIDQAEGPLTYTPMVM
                     NPRLFYLINDVAAYLDESTPACGKYIDLKCQEMVYMITNYYPLPQLRAFFYPISTYTES
                     FQYFVMQNYSKAKNVEEFAHLGGYNTTTFRRLFRNLYGVPVYEWMLEKKREGILEDLQH
                     SNMRITEICNRYGFDSLSHLAHFCKDSFGDTPRALRKKAANGEKIGKITD"
     CDS             complement(9093..10007)
                     /locus_tag="ctg210_10"
                     /transl_table=11
                     /translation="MEHLYDGVTFPEPENLLDWGPETNGRSFKGQTLEELERRWRIASQ
                     DPDKWWCRYPGLPFSTEGMQRTAARRASYQKFIRDYLRCGATVDDNIGKLLNALDEMNI
                     ADNTIVIYVSDQGYFLGEHGFFDKRMFYEESARMPFVIRYPKKVPAGKRLDDLILNVDF
                     APTLAEFAGVKMENVQGDSFVSNLEGNTPTDWRKEIYYRYWTNHAIRPAHFAIRSDRYK
                     LIFYYARNLDMTDTENFDFTPSWDFYDLQNDPHENHNAYNDPKYAPVIKQMKKDLLRLR
                     KETGDTDEKYPEMQELLEKYYNK"
     CDS             10047..10307
                     /locus_tag="ctg210_11"
                     /transl_table=11
                     /translation="MAAHQEGLVAVLLFHPSDGFLGDEVGGEAEHPFAELVVAGPRVGA
                     LYESRVTVFALIVEDGVVVESLRLRLDMPFADESGVVSVGL"
     CDS             10974..11939
                     /locus_tag="ctg210_12"
                     /transl_table=11
                     /translation="MLLPRKIVFFLLLFVGLSLYAQQNCFISSYVRGNFYNRGRISAES
                     LRASDDLIFLNVRPNKDGSLSFENPRIFENGKGVTSWEELIKSVRADVKGTKTKLRLGA
                     ASGEWKAMVADEAARVAFAKNIKKILEKNKLDGIDLDFEWAETEKEYEDYSLAILKMRE
                     VLGDKYVFSVSLHPVCYKISKEAIAAVDFISYQCYGPSPVRFPMEKYCSDIQMALAYGI
                     PKEKLVAGVPFYGVTKDGSKKTEAYFSFVQDGLITGPAQNEVTYKGDVYVFDGQNNIRA
                     KTRYAMDQQLKGMMSWDLATDMPLNDSRSLFKTMVEELGR"
     CDS             complement(11908..16038)
                     /locus_tag="ctg210_13"
                     /transl_table=11
                     /translation="MKTYIAAFFLLLSATFVAAHPYLIQRLGIEQGLSNNYVLSITQDK
                     QGFLWFATEEGLNKFDGTRFITYYKEEQSSSVQSITGNELNEVYADPVQPVIWIATQRA
                     GLNAYNYETQSFSVYQYNPEDPQSLITNDVTHITSSVQAGKGLWVCTYYRGIEYLDIAT
                     GKFTHYNKSTVPALPSEQTWTATEAEDGKLYIGHVEGGLSILSLNDKSVKHFVHDPQNP
                     NSLPGNDVRCIYKDTNGNIWIGTSKGLALFNANTDTFTNFHNNPGNNHGALSSYIFSIK
                     QLKDNKLWIATELNGIMILDLQQNQFLLPEQIRFEFIREGDNNYSLSNASARYIFQDSF
                     NNIWIGTWGGGINFISNAPPAFHTWSYSPTQMNESSLSNKVVSSVCDDGQGKLWIGTDG
                     GGINVFENGKRVAIYNKENRELLSNSVLCSLKDSEGNLWFGTYLGNISYYNTRLKKFQI
                     IELEKNQLLDVRVFYEDKNKKIWIGTHAGVFVVDLASKKVIHHYDTSNSQLLENFVRSI
                     AQDSEGRFWIGTFGGGVGIYTPDMQLVRKFNQYEGFCSNTINQIYRSSKGQMWLATGEG
                     LVCFPSARNFDYQVFQRKEGLPNTHIRAISEDKNGNIWASTNTGISCYITSKKCFYTYD
                     HSNNIPQGSFISGCVTKDHNGLIYFGSINGLCFFNPDIAINSPQIPPVVITKVRIPGRL
                     TSREKNETAIPISEGEIELTHEQNSFNLTFNVQDYSLANQVEYAYMLKGLENSWYTINE
                     QNSVTFRNIPPGKYEFLVKARLHNQDWSEDMTSLRIHITPPLWLTWWAKLIYILITISI
                     IYTIIHAYKKKIDLESLYTLEKKNHEQEQELNQERLRFYTNITHELRTPLTLILGPLED
                     MQKDTSLPTRQAQKLSVIHQSALRLLNLINQILEFRKTETQNKKLCVCKSNIAPLVHEI
                     GLKYKELNQKKAIDFQIQIEKEEMLLFFDKEIITIILDNLISNAIKYTEQGKITLSLYP
                     TTRNGVTYTEIKVSDTGYGISAEALPHVFDRYYQESGKHQASGTGIGLALVRNLVELHE
                     GEIRVESIQNEGSTFYISLLTDNIYPNALHGDSTKQTEEEMISEAVPEDSQNTEPETSK
                     PILLIVEDNEDIQKYIAESFSDSFEVITGSNGEEGKQQALNRIPDIIVSDIMMPVMDGI
                     TLCRQLKEDVRTSHIPVILLTAKDSLQDKEEGYEVGADSYLTKPFSASLLRSRINNLLD
                     SRKKLIAQFQQTGTSHNPNSHLDEKRSIITEALSKLDNEFIEKITQLVEDNLSSEKIDI
                     TYLSDKMCMSGSTLYRKMKALTGLSTNEYIRKVKMQNAERLLLEGKYNISEIAYKIGMN
                     STGYFRQCFKDEFGVSPSDYLKQFTSPTPPPSS"
ORIGIN
        1 cctccctttt ctattgccat gtaaaagatt tcatatattt ttgttgcaaa caggaacaaa
       61 tcaaacgcca acacaaatat atgtcatcaa tctgtcaggg tacttgggat tgtcagaact
      121 gtccgaaagc cgtagacaat gctatcattc acactaccca tacaaggggc taccatcaac
      181 cagcccggaa gtgtgaagat aatttcatcc tttttttgat aaagggagag ctcttggtta
      241 atagtcagga gtatgcaggt acgatgttga aagcaggtga atttattctt caggctattg
      301 gttcaaaata cgagatgctt gcgatgaccg agtgcgaatg tatctattat cgttttattc
      361 agccggaact attctgtgac ttccgtttca atcatatcat gaaggatgta ccttctccgc
      421 ttatctattc tcctttaaag ataattcctg aattgaaata ctttttggat ggttccaaat
      481 cctatttgag tgaaagtaaa gtctgccggg atctgctgtc tttaaagcgc aaagaactgg
      541 cgtttgtgct aagctactat tattcggatt atgacttggc tagtttggtg catccactct
      601 cgaaatacac caccactttt gaatacttca tccttcagaa ctataagaaa gtaaaaacgg
      661 tagaagaact ggctcaactg ggaggttata ccgtcagcac cttgcggcgt atcttcaata
      721 atgtattcca cgaaccggta tacgaatgga tgcaggcgcg acgtaaggaa ggtattttgg
      781 atgacttgaa taactctgag tacagtatct ccgaaatatg ctataaatac ggttttgagt
      841 ctctgcctca cttctccaat ttctgtaaga agttctttgg agcttctcca cgtatgctta
      901 gaacaagcaa gaagaacgtc tgataatttt tcagagagaa agtcaaaaac tatttttttc
      961 tttgtgggtg tagtacattt gttgtatatt gctagctgtt tcctttaaaa ccagtctaat
     1021 acatctttat tataaagtca gatcacttca aataaagcca tgataaggcg gatacggaaa
     1081 ttaaactttt tatttcaacg aattaaaatc aggtttcaaa gcagaataat aacatgatag
     1141 attatgctga atgaatgaaa gataatagga tatttttcta atactctttt gtgtaatcag
     1201 aagagagtct gagtttgaaa tctattatgg cacgtacaat aactaggata taaatcataa
     1261 atactatgta atgagaacaa aacgagcttt taaggaattt tgtgtattgg gtggtttggc
     1321 atcttccgtt tgcggagtag ctcaggagcg cccgaatatt attgttttcc ttgtagatga
     1381 catgggactt atggatacgt cggttccttt tatcgcagat gagagtggtc agccggtgcg
     1441 tcatccgctg aatgactggt atcatacccc gaatatggag agactggcta aacagggtat
     1501 ttgtttttct actttttacg cacagagcgt gagttcccct tccagagctt ccatcatgac
     1561 cggacagaat gcgaccaggc atggagtcac taactggatt aatgctgaga gcaacaatcg
     1621 gaatcctttc ggaccgcccc aatggaactg gaaaggtctc agaaaagata tgcctaccat
     1681 gccgagagtc ctgcaacaag ccggatataa aaccattcat gtaggaaaag cacatttcgg
     1741 ctgtatggga agcgaaggag agaatccgct gaatatcggc tttgatgtaa atatcgcagg
     1801 ttccggcatt ggacatcccg gcagctatta tggcgaatgg ggatacgggc atatcaaggg
     1861 acagaagatt agagcagttc ctgacctgga gaaatatcac ggtacagata ccttcctgag
     1921 tgaagcgctg actatagaag cgaatcggga gatcaccaaa gccgtagaag aaaaacgacc
     1981 tttctatctg aatatggccc attacgcagt tcattcacct ttccaggcag acaaacgttt
     2041 cttgtcacgc tacaccgacc cggataagaa cgagcaggca agagcttttg ctacattgat
     2101 agaaggcatg gataaatcat taggcgacat catggaccaa ctcgaaaagc tggaaattgc
     2161 cgaaaatacg ctgattctct ttttaggaga taacggtggt gatgctccat tgggagatga
     2221 acgtggctat ggttcttccg ctccgctgag aggtaaaaag gggacggagt ttgaaggtgg
     2281 tatgcgtgtt cctttcatcg cagcttgggc aaagcctgag aagaagagca aagtacagaa
     2341 gaacttgcct attgaagtag gaagtatgca gacacagttg ggcacaatca tggatatcta
     2401 tccgactgtt ctgtctgtgg caggatgcga agttccccaa aactacgtga tagacggatt
     2461 cgatctgaaa aagcaactga gcggtaaggt ggacaagaag cgtcccgagt ctttcctgat
     2521 gcacttccct cacgcacacc gcggcagcta cttcaccacc tatcgcatgg gcgactggaa
     2581 actgatttat tattatcttc ccgagactcc gaaacaaccc aaagccttgc tttacaatct
     2641 gaaagacgat ccggaagaaa gaaatgaact ttcttccgca catccggata aatgcaggga
     2701 gatgattcag gaaatgtctg ctcaattaga gaaggaagga gctctttatc cggtggataa
     2761 acaaggaaat gagttgaaac cttttgttta cttttgattg gcattgattt tggtttgcaa
     2821 gagtattgat gtcttatccg caaattgttt taaatgtaat tgcatagaca tttcagtcaa
     2881 tatatgaagt tcagttgata atagttatgc ttcatatata cagctcctta ggttagcgtt
     2941 ctaaggagtt gtataatcct tgcatctcaa attgctatac tatatccttt aaatttactt
     3001 ctagggaatt ggctattttc acaagagtac caatagtgaa attagttctc cctttctcta
     3061 ttcgaataac gttgttgtac tccatttcaa gtttatctgc gaattcttgg atagatagat
     3121 tcttactttc ccgtaatttt ctaattttag tacctatctc atttaaagtt tcctgtttat
     3181 caagcataat ctctgtcata tatgattgtt ttcaaaggaa agtatttata tttgcatatc
     3241 cgcaatcata tatgattgta tggtgagata taataatgct aatggaatat tcagttgagt
     3301 aataacaata aaaaaaatga tgagatggat acacttaatt tgcattcaaa ctttgacaac
     3361 ctactatata taggtagaag cgtattaaat aatacgagca gtcacattca aaaattattc
     3421 tttaaaaaag agatgtgtat atatgagtac ttgtataagg aggaggtaag taaaggcatt
     3481 gaaattaaaa tagatgatgt tgtcttagtc tgtgctttag aacatgataa atgcaataag
     3541 tccattcttt attttaatga cgtagcaaat atcgcacgtt acattcatta ctgtaacagt
     3601 aattttgaat ataaagaaga actcaatggg tggatcatgt cagatagtta tcttgcttta
     3661 tctatatctg aggatgatta tgagaagcga tttgcgttta tacaaacttt actatgaact
     3721 taactgagtc gttttattat acttttgcta atgagtaaaa agaaaatccc ccgccagcta
     3781 acgccgacgg gggatttatg ctattaatca aatcaagctc acgcttagtc tttcagttta
     3841 gcgatgatga agtcgcggtt caggcgggcg atgttgctga tagagatgtt cttcggacat
     3901 tcagcctcgc aagcgcgggt gttggtacag ttaccgaatc cgagttcatc catcttagac
     3961 aacatagctt tcgcacggcg cagagcttcc ggtttacctt gcggaagcaa gttcagctgg
     4021 ctgacctttg cagaaacgaa caacatagca gaaccattct tacaagcagc tacacaagca
     4081 ccgcaaccga tacaagaagc ggcatccata gcttcgtcag cgatgggctt cgggatcagg
     4141 atagcgttgg catcctgcgg agcgcctgta cgaacgctta cataaccacc ggcctgcatg
     4201 atcttgtcat aagcagtacg gtctaccatc aagtccttga tgacagggaa accggccgaa
     4261 cgccaaggct caacagtgat ggtgtcacca tcgttgaaac gacgcatgta aatctggcaa
     4321 gtagtagcac ctgttgcagg accgtgcgga tgtccgttga tgtaaagaga acacataccg
     4381 cagatacctt cgcggcagtc gtggtcgaat acaaccggtt cttttctttc gctgatcagc
     4441 tgttcgttca gaatatccag catttcgagg aaggaagtat caccggggat atctttcatt
     4501 tggtaggttt caaaagcgcc tttagccttc gggcctgctt gacgccatac cttcagtgta
     4561 aatgatatat ttttatccat tttcgtctaa ttcttttaaa tgtttaactt caccgattag
     4621 ctcttgtagt tacgggtctg aaccttgata gcttcgtata ccagcggttc tttgatcaat
     4681 acaggagcct tttcatcgtc accctgatat tcccagcaag ctacgtagaa gaagttttcg
     4741 tcatcacgtt ttgcttctcc ttcttcagtc tggtattctt cacggaagtg accaccacaa
     4801 ctttcgttac ggttcaatgc gtcgtaagca acgagctcgc ccatagtgat gaagtcatac
     4861 agacggatag ccttgtcgag ctcaacgttc ataccttcct tagaaccggg gataaacaga
     4921 ttggtttcga attccttgcg gactgctttc agttcggcga tacctttctt caggccttct
     4981 gccgtacgtc ccatacctac gtattcccac atgatgtgac ccagtttctt gtggatagaa
     5041 tcaactgatt ctttaccctg gatgctcatg aacttgtcga tcttagcctg aactgccttt
     5101 tctgcttcgg caaattccgg aaggtcagta gagaaacgag gaacagtaat ctgatctgcc
     5161 agatagttct ggatagtgta aggcaatacg aagtaaccgt cggccagacc ttgcatcaat
     5221 gcggaagcac cgaggcggtt tgcaccgtgg tcggagaagt tacattcacc gatagcgaac
     5281 agacccttga tggtagtctg cagttcgtag tctacccaga taccacccat tgtgtagtgg
     5341 atagccggat aaatcatcat cggattataa tatttcacac cactgatttc ttttgccagt
     5401 tcgcccggat taacgtcagt gatttcttca tacatatcga agaggttacc ataacgctga
     5461 agcactacat cgatgcccag gcggttgata gcttcagaga aatcgaggaa tacggccaga
     5521 cctgtgttgt tcacaccgaa acctgcgtcg caacgttctt tagctgcacg gctggcaacg
     5581 tcacgtggaa ccaggttacc gaatgccgga taacggcgtt ccagataata gtcgcggtct
     5641 tcttcaggaa tatcgcttcc cttgatttcg cctttctgca atttgatagc gtcttctttc
     5701 ttcttcggaa cccagatacg accgtcgtta cgcagagatt cggacatcag agtcagtttg
     5761 gactgcttgt caccgtgtac cgggatacaa gtcgggtgaa tctgaacgta tgcggggtta
     5821 gcgaatacag cacccttgcg gtagcaagag atagcagctg tacagttaca acccatagcg
     5881 ttggtagaca ggaagtaagc gttaccgtaa ccaccggtag cgattactac ggcgtgagca
     5941 gcgaaacgtt ccagttcgcc ggtgattaag ttcttggcga tgataccgcg tgcacgtccg
     6001 tcgatgatca caacgtcctg catttcataa cgggtgaaca acttcaccgt acctacgttt
     6061 acctgacggc tcagtgcgga gtaagcaccc agcaagagtt gctgaccggt ctggccttta
     6121 gcgtagaatg tacgtgatac ctgtgcgcca ccgaaagaac ggttgtccag tgtaccgccg
     6181 tattcgcgtg cgaaaggaac accttgtgcc acgcattggt cgatgatagc gttggacact
     6241 tcggccagac ggtaaacgtt ggcttcacgt gcacgatagt caccaccttt tactgtatcg
     6301 taaaacagac ggtaaacgga gtcaccatca ttctgataat tctttgcagc attgatacca
     6361 ccctgtgcag cgatagagtg tgcacggcgc ggagagtcct gaatacagaa gttgaatact
     6421 ctgaaaccca tttcaccgag ggatgcagca gcagaagcac ctgccagacc cgtacccaca
     6481 acgatgatat ccaaacggcg tttattagcg gggttcacca atttctggtg agctttatag
     6541 ttggtccatt tctcagccac cgggccttct ggaatttttg aatctatctt gatcataata
     6601 ttatttacaa tttaatcatt tacaatttac tatttagcaa gcaccgccac aaaggagtga
     6661 tttcacgaag aataccacta ctacgagtgc gaaaccgagt actacaatcg tagaatagat
     6721 gttagaaata catttccaac gattgatcca taccttgttg ttccatccca gtgattgcat
     6781 ggagctccag aaaccgtgag tcaggtggaa ccacagagca aacagccaaa tgaggtagag
     6841 cactacataa accggacaag agaatgtctg ctggatgtga tatgcaccgt ttgccgcata
     6901 agccagcgtc agtgtatcag cgtgcatgtc caggttgtgc atcagttccg gcaactgcat
     6961 ttttgcccag aagttgaaga ggtgcaaacc gaggcctacg ataacgataa tgcctaacac
     7021 caacatgttt tgagaagccc actctacagt tttcggtttg tcgactactg catagcgttc
     7081 gctaccgcgc gctgtgcgat tctgcattgt cagccagaac gcgtagatga tgtgaataat
     7141 gaaaagagca gccagtgctg cggtagctac cagcgcatac cagtttgctc ccaaaaactc
     7201 acaaatcatg ttgtaaccat cagccgagat gattgcaact aagttcatcg ccatgtgaaa
     7261 tgttagaaac aggacaaggg cgataccggt aacgctcatc accactttcc ttcctacaga
     7321 tgaattactt aaccacataa atgattgaat ttaaattatt taattgttag aactaaaatt
     7381 tcgacgtttt acacctctta cagactgcaa aaatagggga aatagattga ttgaccaaag
     7441 aattaaagaa ataattcctt aatcggtgat ctttccgatt ttttcgccat tggccgcttt
     7501 cttgcgcaag gcgcgcgggg tgtctccgaa ggagtctttg cagaagtgtg caaggtggga
     7561 cagcgagtcg aaaccatacc ggttgcaaat ctctgtaatc cgcatattag agtgctgtag
     7621 gtcttcgagg atgccttccc gttttttctc cagcatccat tcgtagacgg gcacgccgta
     7681 taagtttcgg aagagacggc ggaaggtggt ggtgttatag cctcccagat gtgcgaattc
     7741 ttcgacgttc ttcgctttgc tgtaattctg catgacaaag tattggaaac tttccgtata
     7801 ggtgctgatc gggtagaaga aagccctcaa ctggggcagg ggatagtaat tggtgatcat
     7861 atacaccatc tcctgacatt tcaggtcgat atatttgccg caggcgggtg tcgattcgtc
     7921 aaggtatgcg gctacgtcgt tgatgagata gaacaggcgc gggttcatca ccattggggt
     7981 gtaggtcagc gggccttctg cctggtcgat gatttcacgg tagcggtttt cgcatagcaa
     8041 cggcagttcg ttgaaccaga aaaggatgta tgatacgtcc gtcagtgcca gtatctcgta
     8101 ttttgagccg atggcttgca ggataaactg tttctcgtgt agtgtcgttc cgggatgttc
     8161 gtcactgttg atcagcaatt cgccctcgat cataaagagc atgcagtttt gcgtgcactt
     8221 atccttcgga atatgctgcc ctctgagcag atttctgtga ataagagtac tttccatcgc
     8281 tttggggcat cctgagcaat ctgtatgttg agcacaaagt gagtcttttg acatgggttt
     8341 tatccgtgaa tcgttgtcta cagggacaaa gatagtcgtt ttttgtgaaa ataaaattct
     8401 ttcttccatt atgttttagc agaaacgggg atatgattgt ctttattggt tttgtttgca
     8461 caactttgaa gtttcacgga ctcctgaatg gcgttcttta atacattaat acatttttat
     8521 ctgccatctg cagcattttc ttcatccctt tacatgatat attcagaaca agtagtttca
     8581 tcattagttc cacctgttga aaccaagtgt ttcaaggcat gaaacaaact gtttcaagta
     8641 atgaaacttc ttggaacaac tgtcgatttc gttcatatga cagctcgatt caactcactt
     8701 gaccgcataa gttgctctga ttgacctgtc cgttcgaaag gtattatttc atttttcagt
     8761 caataatgga tgacttctca gctgttaata cctgatttct caattattaa tagctgacat
     8821 gacaatcgtt aatagctgac gcgtcagatg ttaataccca gtaaatcaaa gtataatgta
     8881 ggataaacga cctatatgcc gtggtggcag agtgagagca aacccttgct ctcactctgc
     8941 caccatactt gctgtaatgc ttgaaatgcc gatgaataaa gggatacacg cgaataatga
     9001 gagcgttagg gcaaaactgc tatctttttc acttgtagca gctgcctaag ttcaagttat
     9061 aaatgcgaca gttcagtttc cgtaccagtc acttacttat tatagtattt ttcaagcagt
     9121 tcctgcattt ccggatattt ctcgtccgta tctccggttt ctttgcgaag tctcaataag
     9181 tctttcttca tctgtttgat gacaggtgca tatttcggat cgttgtatgc attatgattc
     9241 tcgtgcggat cattctgtaa gtcatagaag tcccatgacg gagtaaagtc aaagttctcc
     9301 gtatcagtca tgtctagatt tcgggcataa tagaagatca gcttgtaacg gtctgaccgg
     9361 atggcgaagt gcgcgggacg aatagcatga ttggtccagt agcgatagta gatttctttt
     9421 cgccagtcgg tcggcgtgtt gccttccagg ttgctgacga agctgtctcc ttgcacattc
     9481 tccatcttta ctccggcaaa ttctgccagc gtcggtgcga aatcgacatt cagtatcaga
     9541 tcgtccagac gttttcctgc gggtaccttc ttcggataac ggataacgaa aggcatacga
     9601 gccgattctt cataaaacat ccgtttgtcg aagaagccgt gttcgcctag gaaatagcct
     9661 tggtcggaga cgtagatgac gatggtattg tcggcgatat tcatttcgtc cagagcgttt
     9721 aggagtttgc cgatgttgtc gtcgacggta gcgccgcaac ggaggtagtc acggataaac
     9781 ttttggtagg aagcacgtct ggcggccgtc cgttgcatcc cttcggtgct gaacggcagt
     9841 ccggggtagc gacaccacca cttgtcgggg tcctgtgatg cgatgcgcca gcggcgttcc
     9901 agctcttcca gtgtctgtcc tttgaaagaa cggccgttgg tttccggtcc ccagtccagc
     9961 aggttttcgg gttcggggaa ggtgacgccg tcgtagagat gctccatgcg tatcgggtag
    10021 tcgtagggtt cgtgcgttgc tttgaaatgg cagcacatca ggaagggttg gttgccgtcc
    10081 tgctctttca tccatcggat ggctttctcg gtgacgaggt cggtggagaa gccgagcacc
    10141 cgttcgccga actggtggtt gccgggccac gggtcggtgc tctctatgaa agtcgggtca
    10201 cggtattcgc cttgatcgta gaagatggag tagtagtcga atccttgcgg ttgcgactgg
    10261 atatgccatt tgccgacgag tccggtgtgg tatccgttgg cttgtagcag ggtggcaagg
    10321 gtggggatgg aggtgtccag tgagtccgca agggtgtaca gtctgttccg gtgactgtat
    10381 agaccggtga ggatactggc acggctgggt gctgagatag agttggtgca gaaacagttg
    10441 tcgagcacta ccccttcttt tgccagccgg cggatgttgg cgttgtgggc atattctgcc
    10501 agtactccgc catagatgcc ccaggcttgg gaggtgtggt cgtcactcag gataaaaagg
    10561 atgttggggc gttgtccggc aggttgagcg ccttgcaggt gcgtcatggt tccggctgcc
    10621 agcagaccgg taagtacgag tttattcata tacgtataga tgttgcattt cttcaaaagt
    10681 cagtctaagt tagacggttg ctttcatgta gataaatgat catatgaact gattttatgc
    10741 ctaaagatag tgattgttat tcactttgta ttataatccg gaaaactttt gcgatttaat
    10801 gtaattgatt ccggtaaaac acttaattcc ctttttaaaa ggatgttttt gttttacatc
    10861 tctcaataag aaactttatg ttgatttttg gaagtattat agtgattttt gaacatttgt
    10921 tttctttgcc tgtacctact tttgcgatca aaacccatta attatcaatt attatgctac
    10981 taccaagaaa aattgtattt ttccttctct tgtttgtcgg attatcgttg tatgcgcaac
    11041 aaaactgctt cattagttcg tatgtacggg gtaatttcta caatcgcgga cgtatttctg
    11101 ccgagagttt aagggcgagt gatgatctga tttttctgaa cgtccgtccc aataaagacg
    11161 ggtcgctttc gtttgagaat ccccgtatct ttgagaatgg gaaaggagtg actagttggg
    11221 aggaattgat aaagtctgtc cgtgcggatg tgaaaggaac aaagacaaaa cttcgtctgg
    11281 gcgctgccag tggcgagtgg aaagcgatgg ttgcagatga ggcggcccgt gttgcatttg
    11341 ccaaaaacat aaagaagata ctggaaaaga ataagctcga tggcatcgat ctggattttg
    11401 aatgggcgga gactgaaaaa gagtatgaag attacagtct ggctattctg aagatgagag
    11461 aggtattggg agataaatat gtgttcagcg tatccctgca tcctgtgtgt tataagatta
    11521 gtaaagaggc gattgctgcg gtcgatttca tttcttatca gtgttacggt ccttcgccgg
    11581 ttcgcttccc gatggagaaa tactgttcgg atatacagat ggcgttggct tatggcattc
    11641 caaaggaaaa gctggtggca ggcgttcctt tctatggcgt gacaaaagat ggctcaaaga
    11701 agactgaggc ttacttcagt tttgtgcagg acgggctgat tacggggccg gcacaaaacg
    11761 aagtaaccta taagggagac gtgtatgtct ttgacgggca aaataatatc cgtgccaaga
    11821 cacgttatgc gatggaccag cagctcaaag gaatgatgag ctgggacttg gctacggata
    11881 tgccgctgaa tgacagcaga tcgttgttta agacgatggt ggaggagttg gggaggtgaa
    11941 ctgcttcaga taatctgaag gagagacacc aaactcatcc ttaaaacatt gacggaagta
    12001 gcctgtactg ttcattccta ttttataggc tatttccgag atattatatt ttccttcgag
    12061 gagtaaccgt tccgcattct gcatttttac tttccggatg tattcgttcg tagaaagtcc
    12121 ggtcagcgct ttcatcttcc ggtagagcgt agagccgctc atacacatct tgtcggacag
    12181 gtaagtgata tcgatctttt ccgaagaaag gttatcctca accagttgtg tgattttctc
    12241 aatgaattcg ttatccagtt tgctgagcgc ctcggtgatt atggaacgct tttcatccaa
    12301 atgagaattg gggttatgac tcgttccggt ctgctggaat tgagcaatca gtttctttct
    12361 cgaatcgagc agattgttga tgcggcttcg cagcagtgaa gcactgaaag gcttggtcag
    12421 ataagaatcc gctcccactt cgtatccttc ttctttatcc tgcaatgaat ctttggccgt
    12481 tagcaggatg acagggatgt ggctggtacg cacatcctct tttagttgac ggcatagcgt
    12541 gatgccatcc attaccggca tcatgatatc gcttactata atatcgggaa tacggttgag
    12601 agcctgctgt ttcccttcct caccgttgct gcctgtgatt acttcgaaag agtcggagaa
    12661 agattcggcg atgtatttct gtatatcttc attgtcttct acaatcagca ggataggttt
    12721 gctcgtttcc ggttccgtat tttgagaatc ttccggaaca gcttctgata tcatttcctc
    12781 ctctgtttgc ttcgtagagt ctccatgcaa agcgttgggg tagatattgt ctgttaataa
    12841 gctgatatag aaagtacttc cttcgttctg tatgctttcc acccggattt cgccttcgtg
    12901 cagttctaca agatttcgga ctaaagccag tccgatacct gtgccggatg cctgatgctt
    12961 gccgctttcc tgatagtaac ggtcgaaaac atgaggcaag gcttccgcag agattccgta
    13021 tcccgtatca ctgactttaa tctccgtata agtgactccg tttcgtgtgg tgggatacaa
    13081 gctcaaggtt atttttccct gttccgtata tttgatggca ttggaaatca gattatcgag
    13141 gataatggtg atgatttctt tgtcaaagaa cagaagcatc tcttcttttt ctatttgaat
    13201 ctgaaagtcg attgctttct tttgattgag ttctttgtat ttgagtccga tttcatgaac
    13261 gaggggcgcg atgttgcttt tgcaaacaca tagctttttg ttctgcgttt ccgttttccg
    13321 gaactcaaga atctgattga tcaggttgag cagccggagg gcactctggt ggatgacaga
    13381 aagtttctgc gcctgtctgg tcggcagtga cgtgtctttc tgcatatctt ccagcggacc
    13441 gaggatcagg gtcagtggtg tgcgcagctc atgagtgatg ttagtataga atcgcaagcg
    13501 ttcctgattc aattcttgtt cttgttcgtg gtttttcttt tccagcgtat agaggctttc
    13561 gaggtctatt ttcttcttat aggcatggat aatagtataa ataatgctga tagtgatcag
    13621 aatatagata agttttgccc accatgtcag ccagagagga ggggtgatat gtatcctgag
    13681 agaggtcatg tcctccgacc agtcctgatt gtgcaggcgg gcttttacca gaaactcata
    13741 cttgccggga ggaatattac ggaaggtgac gctgttttgc tcgttgatcg tataccatga
    13801 gttttcaagt cctttcagca tataggcata ttccacctgg ttggccagtg aatagtcctg
    13861 tacgttgaaa gtaagattaa aactattttg ttcatgagtc aattctatct ctccttcgga
    13921 aatgggaata gcggtttcgt tcttctcccg acttgtgagt cgtccgggaa ttctcacttt
    13981 agtgataacc acaggaggaa tctgcggact gtttatggca atatcggggt tgaagaaaca
    14041 caatccgttg atagagccga aatagatgag cccgttatga tctttggtaa cgcatccgct
    14101 gatgaaactt ccttgtggga tgttgttgga gtgatcgtag gtatagaaac attttttaga
    14161 ggtgatatag caactgatgc cggtattggt acttgcccag atgttgccgt tcttatcttc
    14221 actgatagct cttatatgtg tattgggcag tccttctttt ctttgaaaaa cctgatagtc
    14281 aaaattgcgg gccgaaggaa aacataccag cccctcaccg gtggcaagcc acatctgacc
    14341 tttgctgctc cggtatatct gattaatcgt attggaacaa aaaccttcgt attggttgaa
    14401 cttcctgacc agttgcatat ccggcgtata tatcccgact cctcctccga aagttcctat
    14461 ccagaaacgt ccttcactgt cttgggcaat gctgcgtaca aagttttcca gcaactggct
    14521 gttggaggtg tcataatgat gaatcacctt cttgctggca aggtctacaa cgaacacccc
    14581 tgcgtgagtt cctatccata tctttttatt cttgtcttca tagaagacgc gtacgtcgag
    14641 aagctgattc ttttccagtt cgatgatctg aaacttcttc agtcttgtat tgtaatagct
    14701 gatgttgccc agataggtgc cgaaccatag gttgccttcc gagtctttca gcgaacaaag
    14761 cactgagttg gacaggagtt ctctgttttc tttattgtaa atggccaccc gttttccgtt
    14821 ttcgaatacg ttaatacctc ctccgtcagt tcctatccac aattttcctt gtccgtcatc
    14881 gcagacgctg ctaacgactt tgttgctcag cgaactttca ttcatttggg tgggtgaata
    14941 gctccatgta tggaatgcgg gaggagcatt gctgataaaa ttgattcctc ctccccaagt
    15001 ccctatccag atattattaa aagagtcttg aaagatatac cgtgcgctgg cgttggacaa
    15061 actgtagtta ttgtcccctt cgcggataaa ctcaaagcgt atttgttcgg gcagcagaaa
    15121 ctgattttgc tgtaagtcca gtatcatgat cccgttcagt tctgttgcaa tccagagttt
    15181 gttgtctttg agctgcttga tggagaagat atagcttgac aatgctccgt gattattccc
    15241 cggattgtta tgaaagttgg taaatgtatc tgtattggca ttgaacagag ccagaccttt
    15301 gctggttccg atccatatat ttccgttggt atctttatag atacaacgca catcgttccc
    15361 cggaaggctg ttcgggtttt gaggatcatg gacgaagtgc ttcacggatt tgtcattcag
    15421 ggagaggatg ctcaacccgc cttctacgtg tccgatgtat agtttgccat cctcagcctc
    15481 cgtggctgtc caggtctgct cagagggaag ggcgggtact gtacttttgt tataatgagt
    15541 gaatttcccg gtagcgatgt ccagatactc tatacctctg taataagtac atacccataa
    15601 ccctttgccg gcttgtacgg atgaggtaat gtgagtgaca tcgttcgtta tcagactttg
    15661 cgggtcttcc ggattatatt ggtagacgct gaaactttgt gtctcgtaat tataagcgtt
    15721 gagtcctgcc cgctgggtgg ctatccagat aacaggctgc acgggatcgg cgtacacttc
    15781 attgagttcg ttgccggtaa tgctttgaac agaagaagat tgctcctctt tatagtaggt
    15841 gataaagcgg gttccgtcaa acttattcag cccttcttcg gtggcgaacc acagaaatcc
    15901 ctgcttgtcc tgcgtgatac tcaatacata attgttggat aagccttgtt ctattcccaa
    15961 tctttggatg aggtaagggt gggctgccac aaatgtggcg gatagcagga ggaagaaagc
    16021 cgcaatgtat gttttcatcg tttcagatat tatgtattcc ttgatattca ctctcaaaag
    16081 tacaaataaa tcttgtattt agtatagaca aatgattcat tgcatgattt tctacccttt
    16141 ctgcatgatt tttacagcga ataaaataaa acaactgtaa ttttgcaatc aatcaaataa
    16201 ccgaatctaa tacttgcaga aaatggaatc tgattcttta cacgaacatg ataaaagctg
    16261 gaaggcattt tttattacca ctctgttcat cttgtgtaca gcgaacgttt atgcgcagtc
    16321 atccgataca atcttttccc gatatttccg ttatgcgcag aacttcgcag atgcgtaccc
    16381 tcgcgagaaa gtgagtcttc atttggataa tgcaagttat taccttggtg atacgatttg
    16441 gttcaaagcg tatgtagtga cggctgaaca aaacttaccg acgacgatca gcaaaccttt
    16501 gtatgtagaa ttactggacc agttgggaaa tgtcgtagag cggcaaatta ttcagcttac
    16561 ggatggggag ggaacgggac aaatcatttt gaacaatacc ttctttaccg gttattatga
    16621 aatgcgtgcc tatacaaagt ggatgcttgc ttttgataac ccttcctgtt tttcccgtgt
    16681 attacccgtc tatcggaaac ggctgagcga tgaagagact cctcggagta tagctaccta
    16741 tcgtatggac gcttcgatga aacagaggcc gaaggataaa gagaagaagt ttacagtccg
    16801 cttttttccg gagggtggac aactggttaa aggcatatct tcgattgtag cttttgaagc
    16861 caccagccgt gacaaaggag ctgctgatgt agagggaaca gtggttttgc cgagtggtga
    16921 agaactggcg catatccgtt cattgcatga cgggatgggt tactttgagt ataagcccga
    16981 agaaaaggcg ggtgtggcaa aaattgatta tgaaggctcc acttatcagt ttgaccttcc
    17041 ggaagctctt ccacaaggat atgtactccg aatcgataac cggcgggaaa tgttggatat
    17101 cactgtagcc cgcagttcac aggcaatgaa agacacactg gctgtttttg tatcttctca
    17161 ggggcgacct tacaaatgta tgacactgga ctttgaagat gaattgaact gccaattccg
    17221 gatttcgact aaagaactac cgcccggagt gcaacagata tctctggtca atctgaaagg
    17281 ggaaacgtta tgcgagcgtt tttgttatgt gatgccgcgt tcttccatgc tccttgcc
//
