LOCUS       gnlProkkaKAMAOBPD_43   13256 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KAMAOBPD_43.
ACCESSION   gnlProkkaKAMAOBPD_43
VERSION     gnlProkkaKAMAOBPD_43
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 08:47:23
            Original ID  :: gnl|Prokka|KAMAOBPD_43
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13256
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13256
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[2989:3256]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2990..3256
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..13256
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13256
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             3..80
                     /locus_tag="ctg43_1"
                     /transl_table=11
                     /translation="MEDRQSVVDKIQALVDAGEYPAKLF"
     CDS             complement(125..1795)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 277.2; E-value:
                     4.8e-84)"
                     /gene_kind="transport"
                     /locus_tag="ctg43_2"
                     /transl_table=11
                     /translation="MKKQQKDKKVKKDRREKLRYIREVSAEQRGRILLSCLTGILGVAF
                     ALAFIYATKRVIDTATGITDDNLTHIAVLTVVLLTAQLLCGAADTWISTRMQIETGNAL
                     RHRLFSRLLQSRWNELERFHTGDVVNRVEQDTTAIVTLLTSSVPAFIVTSIQLLAAFLF
                     FYFLDPSLPWLIVAILPVFLSGSRFYMRRMKRYTHDIRNSDGRIQSVIQESLQHRIVIK
                     TLEQGERHLDKLDDLQDMLHSQVMGRTRFSLSAHMLVALAFSGGYLTAFLWGAVHLSAG
                     CITFGTMTAFLQLVGKVQRPVFDLSRLIPSVVNALTAIDRLLELERLPAEADGDSIFLA
                     STPKLELKDVTFRYTPDDRPVFSRFSCRFPAGSCIAIVGETGKGKTTLIRLLLALATPQ
                     EGQILLIPAKHPLETSHTVSPQTRKNFVYVPQGNTLFSGTIRDNLLMGNPQASQEAIYQ
                     ALQTATADFVFHLPDGVDSPLSERGGGLSEGQAQRIAIARALLRPGNILLLDEATSALD
                     PDTERLLIKNLRRDCAGKTCIFVTHHPAVAEACESIVRL"
     CDS             complement(1818..2981)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_5"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_3"
                     /sec_met_domain="NTP_transf_5 (E-value: 8.4e-46, bitscore:
                     147.6, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQHAFFSLVRSGLWGTPADRQLFRSVSPDDWETVYRMANSQALLA
                     LTFDGISSLPAELRPPRVLYLKWAARTAQIEQANKRLNQLLPELNTLYREAGLHPVLLK
                     GQGIGTNYRTPLHRQCGDIDIYLGKQGQPIANRLLLQQGAIVEGEASDKHASYSLKGVH
                     IENHRIILRLNSPLANRHFQQIIRKWYPQETDYALFSETGKEDSKAVSIAIPPATFNAL
                     YIFLHAFVHFLNSGIGLRQLCDWTCLLANRHKEIDATTLLRQLQDLGLLHAAQAFGYIA
                     VTRLGLPANRLPFPLEGTKQIGEQLLEDILSTGNFGQHDNRIKPRPKGYWAGKWYTFCR
                     ATRRCNELRQFAPYEALWYPVTLIGGTIAIQINRSKGVKDKKARTKK"
     CDS             complement(2990..3256)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg43_4"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 2.8e-13,
                     bitscore: 41.0, seeds: 25, tool: rule-based-clusters)"
                     /sec_met_domain="PF05402 (E-value: 1.3e-15, bitscore: 48.7,
                     seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIKQGFILHRIGDDYIIMQDGSSNVDFSKVISLNQTSAMLWQEI
                     ENKEFDTDSVTEALTSRYDVDNESARRDAQKFIDSLDREGIIE"
     CDS             complement(3269..3613)
                     /locus_tag="ctg43_5"
                     /transl_table=11
                     /translation="MNPFLVDRRDRVTLGDFTTEQLQPGVTVLARDLTERIVFHRIIRR
                     NGDILILQGDGNLAQTEETDIGRVMGVMTEAMRKDKRYTADGKVWKLYSYWWMKLNPAR
                     RWLLALFRRI"
     CDS             complement(3736..4647)
                     /locus_tag="ctg43_6"
                     /transl_table=11
                     /translation="MDYQVGPHTFRMVKPSDFNIFKALPSLIPFITTIDTTQKVIFETE
                     IDDDETTTKRTIAKTPDDICFNWEDADCIIRPLPHSSHLVSITPRKSGKNYWMECNDNF
                     RQCFIHLPACRTETPAPENETNFVLNNFLMMLYAFNAARHHTLLMHASVVATETGKGYL
                     FLGKSGTGKSTHTGLWLQQFSDCHLLNDDNPIVHVDSLGKQATVFGSPWSGKTPCYRKE
                     SMTVGAFVRLEQAPQNEIEQERAAHAFATLLPSCSCLKQNKEIYNAIVATVTELATLAP
                     VYHLKCLPDREATELCRKTVEG"
     CDS             complement(4770..4958)
                     /locus_tag="ctg43_7"
                     /transl_table=11
                     /translation="MGGKNILLAKQVRRTDKPNSKKGSNISSQTKRRDIGIALLLSFRC
                     GGQRIFFYRSASSASKE"
     CDS             complement(4909..6639)
                     /locus_tag="ctg43_8"
                     /transl_table=11
                     /translation="MTATTAQQTLIINAGVTVKKLTVKGGNLKIYGKVEQLVHDAGNTT
                     IYIIKGTEASLPATIDSKFVVQSDVAVLKTAFANGEDFKLSADADITGQSVSVPAGKSV
                     VLDLNGYTLTADNSATGKIIVLGKMTLKDSSTEKKGKIVASQDYTAASYNGSLIEIAGE
                     DASMTMESGNISAVRETPDSNGQYGVGVTDGGDFTMTGGKIEAGWFAVAGNGNYKTQNS
                     IINITDGELISTADYAVYLPQSGTTTISGGKVYGAAGGVCIQRGTLNVEGTALITSKGT
                     GSTGNWGDGTGKLGCAAINVSGAYGIATVNIKGGTLTAEAESLITEGTDYTPVINVTGG
                     TFSDPSVLKYMATNATVDIKLLSNINIAKTELATGYILNAANATANLNLNGHDIINSSE
                     TADATPFTQIFTVQNGTLNISGNGNVKCDASATAKDDGYRMVIEARGYGTVNIHGGSYY
                     NTQKLNTQIDLIYARENGKINIYGGTFESGKYGTPNNDTDGRYWVLNLKNTDKNTASIQ
                     VSGGTFINFNPANPNMDDNESYLVTGYEVTRDGSVYTAAHKVGDGRKEYIVGQTSQENR
                     "
     CDS             6659..7162
                     /locus_tag="ctg43_9"
                     /transl_table=11
                     /translation="MPTAANVTVVLGMVMATEGASCSAVVSGTAKDTLLVAVAAGALTL
                     VLVLSVSVNGAAVLVVGAVLNVRLMSEFCKTGMAMPSLLPEVVLKLPLTAMSVTVAAVG
                     ASCGRFFESAKAVLSALGVVASTTTQSKGGTTNMSLLPKILSLSVLVKYTLSLPFVSWA
                     VMEL"
     CDS             7217..7465
                     /locus_tag="ctg43_10"
                     /transl_table=11
                     /translation="MKEAVISLLSSLVTASIGSAAVKSTVQIPAMLLEAIILKVVASAG
                     ILLTVSFIMAAMCLKDRALRLSGFVTLAYIGLLLLPL"
     CDS             complement(7883..8098)
                     /locus_tag="ctg43_11"
                     /transl_table=11
                     /translation="MKQNTPDGREAYITPSIEVIKMENEGVIATSGEPYHPITRSYSGS
                     TSTHSYNSASSSDLEDLINDILTVEN"
     CDS             complement(8464..8790)
                     /locus_tag="ctg43_12"
                     /transl_table=11
                     /translation="MKNCYGIDFRSWRKELRTREKTKQTPCKLPDRASRSLQGVLFKVY
                     QISVLILLKKILFSFFSVCLPLFIRHIAAMLLRKTSSKTMQTVTKYLKELSGVRSDNSP
                     NSYK"
     CDS             9656..9988
                     /locus_tag="ctg43_13"
                     /transl_table=11
                     /translation="MKQLIACCGLDCENCAARIATVNNDDELREKTAKEWSVLNNTPEI
                     TPETIHCMGCRADGVKFAYCSDYCAIRKCVYEKGFNTCGDCKELETCQVVGAVLQHAPG
                     AKENLY"
     CDS             10222..10998
                     /NRPS_PKS="Domain: oMT (51-145). E-value: 2e-11. Score:
                     34.4. Matches aSDomain: nrpspksdomains_ctg43_14_oMT.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1089:methyltransferase (Score: 81.7; E-value:
                     9.7e-25)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg43_14"
                     /transl_table=11
                     /translation="MSNENKTIHDFEFNLICDFFSNMERQGPGSPEATLKALSFVDGLT
                     DESLIADIGCGTGGQTMVLAGHVPGQITGIDLFPGFIDIFNRNARQLGLQDRVKGIVGS
                     MDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGYIAVSESSWFTDERPAEIN
                     DFWMDAYSEMDTLPNQVAKLYKAGYLPVATFILPENCWTEHYFASKVAAQEIFRKKYAG
                     NKIAEEFSSLQMIEDELYGKYKEFYGYVFFIAKKVG"
     aSDomain        10375..10656
                     /aSDomain="MT"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg43_14_oMT.1"
                     /domain_subtypes="oMT"
                     /evalue="2.00E-11"
                     /label="ctg43_14_oMT.1"
                     /locus_tag="ctg43_14"
                     /protein_end="145"
                     /protein_start="51"
                     /score="34.4"
                     /tool="antismash"
                     /translation="DIGCGTGGQTMVLAGHVPGQITGIDLFPGFIDIFNRNARQLGLQD
                     RVKGIVGSMDALPFGEEELDMIWCEGAIYNIGFERGLKEWRKYLKPGGY"
     CDS             complement(11073..11942)
                     /locus_tag="ctg43_15"
                     /transl_table=11
                     /translation="MRLKISNMNISEFNINDEFIACNHITTNELNPLVEKPYHTKASIF
                     ALCTKGVLKTIINHTQFRVEANALLVIPPETFVQLLHTSDDAEIYVVIFSQQLIQSSGA
                     GKVMMDKFHIIGKHYIFPLSKTDFQLYAEFMTYLSHLYQRTESPSSLVSLQTLLAYLLQ
                     GISELCPERPRIKETPGSRHFNQYRIFIRLVHTDYVREHQVSYYALKMNMRPAALCRLV
                     KKESGYTAMEIINNTIIMDAKAQLCTANTPIKDIAVSLGFNNAAFFNKFFKRHTGIPPQ
                     KFRTSSKQ"
     CDS             complement(11932..12162)
                     /locus_tag="ctg43_16"
                     /transl_table=11
                     /translation="MRNIRIHQNWFIIQEAKFGLKCLYHKQTLINQYSILICIYSIIHN
                     FTLFNRDKLSVILILTVTSVIYTLLSPIFAS"
     CDS             complement(12205..12297)
                     /locus_tag="ctg43_17"
                     /transl_table=11
                     /translation="MLIQLEFIHHLLIQTPDTIFQINHNNADGP"
     CDS             complement(12433..12708)
                     /locus_tag="ctg43_18"
                     /transl_table=11
                     /translation="MNQKCEFLRRQRIVTRRNPQIFKITRFYNHQIMFHVERPLKYLGA
                     AQRNIQQMLLCPFFQHIPKIEYNPHQLSIFMNSHHSTLYQKTDTTL"
     CDS             complement(12837..13208)
                     /locus_tag="ctg43_19"
                     /transl_table=11
                     /translation="MPFKETFSKWNSIVFDSILDKSRISEINTINNWLFFSIKDVNSII
                     SCRDKSASPQASSVEKPTMAFSGVRISWLILARNTLFNSSLRCAFCKASFNLFSVSLYF
                     CVLMQIPMIRNGKSVNCPT"
ORIGIN
        1 atcccgaaga ccgtcagagt gtagtcgaca agattcaggc tttggtggat gcgggcgagt
       61 atcctgcgaa gctgttctga gtttgttaac caaaggcaga tacccgttgg ggctcattct
      121 ctgattataa tcggacaata gattcgcatg cctccgctac tgccggatgg tgggtgacga
      181 agatacatgt tttgcctgcg cagtctctgc gcaggttttt tattaacagc cgttccgtgt
      241 cggggtcgag ggcagaagtg gcttcatcta aaagaagaat gtttccgggg cgtagcagag
      301 cgcgggcaat ggcgatgcgt tgggcttgtc cttcactgag tccaccacct cgttcgctga
      361 gtggggagtc tacgccgtcg ggaaggtgga agacgaagtc ggcggtggcg gtttgcaggg
      421 cttgatatat ggcttcttga gaagcttgtg ggtttcccat cagcaggttg tcacggatag
      481 ttccgctgaa aagggtattg ccttgcggga catatacgaa gttcttgcgg gtttgcggag
      541 agacggtatg actggtttca agtggatgtt tggcgggtat caagagtatc tgtccctctt
      601 gtggcgttgc cagtgccaac aatagccgga tgagcgttgt ctttcctttt cctgtttctc
      661 cgactatagc tatgcagcta ccggcgggga aacggcagga gaagcggctg aataccggac
      721 ggtcatcggg agtgtagcga aaagtcacgt ctttcagttc cagtttcggg gtagaggcga
      781 ggaatatgct gtcaccatcc gcttctgccg gcagtctttc caattccaat agccggtcta
      841 tggcggtaag ggcattgact acggaaggta tcaggcgtga gaggtcgaac acgggacgct
      901 ggacttttcc taccaattgc aaaaaggcgg tcatcgttcc gaaggtgata cagcctgcgc
      961 tgaggtgaac ggctccccaa agaaaagccg tgaggtatcc gccggaaaag gcaagggcca
     1021 ctaacatgtg ggcagaaagc gagaaacggg tacgtcccat gacttggctg tggagcatgt
     1081 cttgcaagtc atcgagtttg tccagatgcc gttcgccttg ttccaatgtt ttaatcacta
     1141 tgcgatgttg caggctctct tgtatgacgg actggatgcg accgtcactg ttccgaatat
     1201 catgtgtata gcgtttcatt cgtcgcatat agaaacggct gcctgataga aagacgggca
     1261 ggatggcaac aatcagccat ggcagtgaag ggtctaaaaa gtagaagaat agaaaggctg
     1321 ccagcagttg tatactcgtg acgatgaatg ccgggacaga agaggtgagc aatgtgacga
     1381 tggcggtggt gtcttgttct acccggttca ctacgtctcc ggtatggaaa cgctccaatt
     1441 cgttccagcg gctttgcagt aagcgcgaga agaggcggtg gcgaagggcg ttgcccgtct
     1501 ctatctgcat acgggtactt atccaagtgt cagcagctcc gcacagtaat tgggcagtca
     1561 gcaggacaac ggtgagaacg gcgatatgcg tcaggttgtc gtctgttatt ccggtagcgg
     1621 tgtctatcac ccgtttggtt gcatagataa aggctagggc aaaggccacg cccagaatgc
     1681 cggtgaggca acttagcagg atacgtccgc gttgttcggc agatacctct cgaatatacc
     1741 taagtttttc acgtctgtcc tttttcactt ttttgtcctt ctgttgcttt ttcattcctt
     1801 ttattttccg ggttctttta tttctttgtc cttgctttct tgtcttttac tccttttgat
     1861 cggtttattt gtatagctat cgttccccct atcagagtca cgggatacca gagtgcttcg
     1921 tacggtgcaa attgacgcag ttcgttgcag cgtcgggtgg cgcggcagaa ggtgtaccac
     1981 tttcctgccc aatatccttt ggggcgtggc ttgatgcggt tatcatgttg cccgaagtta
     2041 ccggtagaca ggatgtcttc caataattgt tctcctatct gcttggtgcc ttccaagggg
     2101 aaaggaagcc ggttggcggg caatcccagt cgggtgacgg caatgtagcc gaatgcttgt
     2161 gcggcatgca atagtccgag gtcctgcaac tggcgaagca gggtggtggc atctatttct
     2221 ttgtggcgat tggcaagcag acaagtccag tcgcatagct ggcgcaggcc gattccgctg
     2281 ttcaggaaat gtacaaaggc atgcaggaag atataaagtg cattgaaggt ggccggaggt
     2341 atggcgatac tgacggcctt cgagtcctct ttcccggttt cggagaatag ggcatagtct
     2401 gtttcctgcg ggtaccattt tctgataatc tgctgaaagt gccggttggc aagcggactg
     2461 ttcagccgga ggatgatgcg gtggttctcg atgtgtactc ctttcaaact gtagctggca
     2521 tgcttgtcgg acgcttctcc ctcgactatg gcgccttgtt gcagcaggag gcgattggct
     2581 atgggttgcc cttgttttcc taaatagatg tcgatgtctc cgcattgccg gtgcaaggga
     2641 gtgcggtagt tggtgccgat gccttgccct ttcagcagta cgggatgcag cccggcttcc
     2701 cggtaaaggg tattgagttc gggcagaagc tggttgaggc gtttgttggc ttgttctatc
     2761 tgtgcagtcc gggcagccca tttcagatag aggacgcgtg gagggcgcag ttcggccggc
     2821 agactgctta tgccgtcaaa agtcagtgca agcagggctt gtgagtttgc catgcggtac
     2881 acggtttccc agtcgtccgg cgagaccgac cggaagagtt gtcggtctgc cggagtgccc
     2941 cacaggccgg agcgtaccaa tgaaaagaaa gcgtgttgca tatccgtcct tattctatga
     3001 ttccttcgcg gtcaagggag tcgataaact tctgcgcatc gcgacgggcc gattcgttat
     3061 ctacatcata gcggctggtc agggcttctg tcacgctgtc tgtatcgaac tctttgtttt
     3121 ctatctcttg ccaaagcatg gcggaagttt ggttcaggct gatgactttg ctgaagtcca
     3181 cgttcgacga gccgtcttgc atgatgatgt agtcatcgcc tatccggtgc aggataaatc
     3241 cttgtttgat tttcatggtt attttgtttt atattcttct gaacagggcg agcagccagc
     3301 ggcgagcggg gtttagcttc atccaccagt aggagtagag cttccagact ttgccgtcgg
     3361 cggtgtaccg tttgtctttt cgcatggctt cggtcatgac gcccattacc cgtccgatgt
     3421 cggtttcttc ggtctgggcg aggttgccgt cgccttgcag gatgagtatg tctccgttcc
     3481 gacggatgat gcggtgaaag acgatgcgtt ccgtcaggtc gcgtgccagt acggtgacgc
     3541 ccggttgcag ctgttctgtg gtgaaatcgc ccagtgtcac ccggtcacgg cggtccacta
     3601 agaaaggatt catgctgttg ccccgcacgg tgatggttac tgtatgtccc tctttgatga
     3661 gacgcgccac ttcgggaagc aatatctcgt tgggaatgct tttcttcatc ggctgttcag
     3721 ttcatcattc ataacttatc cttctaccgt ctttctgcaa agttccgtcg cttcacggtc
     3781 gggtaggcat ttcagatgat agacgggtgc cagcgtggca agttccgtca cagtggcgac
     3841 aatggcgtta tagatttcct tgttctgctt taggcaagag caggagggga ggagggtggc
     3901 gaaagcatgt gctgctctct cttgctctat ttcattctgc ggtgcttgtt ccaagcggac
     3961 gaaggcgcct acggtcatgg attctttccg atagcaaggt gtctttccgc tccacggaga
     4021 accgaaaaca gtggcttgct tgccgaggct gtccacatgt actatcggat tgtcatcgtt
     4081 cagtagatgg cagtccgaga actgttgcag ccagagcccg gtgtgcgtac ttttgcccgt
     4141 gccgcttttc cctaagaaga ggtagccttt gcctgtttca gtagcgacaa ccgaggcatg
     4201 catcagcagt gtatggtggc gggcggcatt gaaggcatag agcatcatca agaagttgtt
     4261 cagtacgaag ttcgtttcgt tttccggagc cggtgtttct gtcctgcagg ccggtaggtg
     4321 gatgaagcat tgcctgaagt tatcgttgca ctccatccaa tagtttttcc cgcttttccg
     4381 tggggtgatg gatacaaggt gtgagctgtg gggcaaaggg cgaatgatgc aatcggcatc
     4441 ttcccagttg aaacatatat catcgggagt tttcgctatg gttcgttttg tcgttgtttc
     4501 gtcatcgtct atctctgttt caaagattac tttttgcgtc gtgtctattg tcgtgatgaa
     4561 cggaatcagt gaaggcagcg ccttgaatat attgaagtcg gaaggtttca ccatgcgaaa
     4621 ggtgtgcggt cctacttgat aatccaatat ctgtattctc atatgttttg attgttagtt
     4681 gttattcatg atactttggg ctactcagaa aaataatgaa tgtttgtgtg aatgaggaag
     4741 atttgagaga tttttcaact gtcttgttgt cattctttag acgcggagga cgcagatcta
     4801 taaaagaaaa tccgctgtcc gccgcatcta aaagatagta ataaggcgat tccgatatct
     4861 cttcgtttgg tttgcgagga tatattgctt cctttcttag aatttggctt atcggttctc
     4921 ctgacttgtt tggccaacaa tatattcttt cctcccatca ccgactttgt gggctgctgt
     4981 atatacactg ccgtcacggg taacctcgta gcctgttacc aaataggact cattgtcgtc
     5041 catattcgga tttgccgggt tgaaattgat gaacgttcca ccggacacct ggatgctggc
     5101 agtgttcttg tctgtattct ttaagttcag tacccagtat ctgccatccg tgtcgttgtt
     5161 gggtgtacca tatttgccgg attcaaatgt tcctccatag atattgattt tcccattctc
     5221 tcttgcataa atcaggtcta tctgggtgtt cagtttctgg gtgttatagt aagaaccgcc
     5281 atgaatattt actgtcccgt atcctcgggc ttcaattacc atgcgataac catcgtcttt
     5341 cgctgtagca gatgcatcgc acttcacatt gccgttgcct gaaatgttta gtgttccgtt
     5401 ctgtacagta aagatttgtg tgaaaggagt ggcatcagct gtttctgagg aattgatgat
     5461 gtcgtggcca ttcaggttta agtttgccgt tgcgtttgca gcattcaata tgtagcctgt
     5521 ggcaagctcc gtcttggcga tgttgatatt tgagagaagt tttatatcca cagttgcgtt
     5581 ggttgccatg tacttcagta cgcttgggtc ggagaatgta ccgccggtaa cgttgatgac
     5641 cggtgtataa tcggtgcctt ctgtgatgag tgactctgct tctgcagtca gtgtaccgcc
     5701 tttgatgttt actgtggcaa tgccgtatgc tccacttacg ttgatggcgg cgcagcccag
     5761 ttttccagtg ccatcgcccc agttgccggt gctacctgtg cctttactgg taatcaaggc
     5821 tgtaccttcc acattcagag tgcctcgttg gatgcataca cctcctgcgg caccataaac
     5881 cttgccgcca ctgatggtcg ttgtgccgga ttggggcaga tagactgcat agtcagcagt
     5941 agaaatgagt tctccgtctg tgatgttgat gatggagttc tgcgtcttgt aattgccgtt
     6001 gcctgccact gcaaaccatc cggcttctat cttgccgcct gtcatggtga agtctccacc
     6061 gtccgtcact ccgacgccat attggccgtt actgtccgga gtctctctga ctgcactgat
     6121 gttgccgctt tccatggtca tggaggcatc ttcaccggct atttcaatca gactgccatt
     6181 ataagaagcc gctgtataat cctggctggc aactatcttg cctttcttct cggtagagct
     6241 gtccttcagt gtcatcttgc ccaagacgat gattttgcct gttgcgctgt tgtcggcagt
     6301 cagtgtatat ccgttcaagt caagaaccac ggactttccg gcgggtacac tgacgctttg
     6361 ccctgtgatg tcggcatcgg cggacaattt aaaatcttcg ccgttggcga aagcggtctt
     6421 taggactgcc acgtcggatt gaactacaaa tttgctgtcg attgttgccg gaagtgatgc
     6481 ttcagttcct tttattatat agattgtggt attgccggca tcgtgtacca attgttctac
     6541 ctttccatat atcttcaagt taccgccttt tacagtcagc ttctttacgg tgacgcctgc
     6601 attgataatc aatgtctgct gggcggtagt ggcagtcact tcattgtaag tggctttatt
     6661 gcctactgct gccaatgtaa cggtggtgct tggcatggtg atggctacag aaggagcttc
     6721 ttgctctgct gtggtttccg gtacagccaa ggatacactg ttggtggcag tggcggcggg
     6781 agcacttacg ctggtattgg tcttgtcggt cagcgtcaac ggagcggcag tactggtcgt
     6841 tggggctgta ttgaacgtca ggttgatgtc cgagttctgt aaaaccggga tggcgatgcc
     6901 gtcgttgctg ccagaagtgg tattgaagct gccgctgact gcaatgtcgg ttacagttgc
     6961 tgctgtcggt gcttcttgtg ggagattttt tgaatcagct aaagctgtac taagcgcact
     7021 gggggttgta gcatctacaa caacgcaatc caaaggaggt actaccaata tgtctcttct
     7081 ccctaagatt ttgtcattaa gcgtcttggt aaaatatacc ttgtcgcttc cattcgtcag
     7141 ttgggcagtg atggaactat aagtacctgt gggcaaagga atgtagaagt tgcgagactt
     7201 tatatcagct gaggctgtga aggaggcggt gatttccttg ctttcatcgc tcgttactgc
     7261 cagtatcggg tctgctgcgg ttaagtctac cgtacaaata cctgcaatgt tattggaggc
     7321 aataatcttg aaagtagtgg cctctgccgg aatcttgttg acggtcagtt ttatcatggc
     7381 tgccatgtgc ttgaaggaca gagcgctcag attgtcggga tttgtcacct tggcatacat
     7441 cgggctattg ctgctgccgt tataatttgt aagcgtggca ggtagagtca tggtcaatgt
     7501 attgccgctt acgctcatgt tttgttggta aggatagatg gagaatacag ccgtttctcc
     7561 gcttggcttg ctgccgttga aagtggcgga agtttgacca gcaccgcttg catattctaa
     7621 ttttgtattg ctataattac tttctgcatt actacagaac aaccctaggg catcggtatc
     7681 ttgccataga atcttgtatt catcgtttac ggtagtacgg gtgtcggtac ctgcgccttc
     7741 aaacgttgcg ttaacggtga tgtttccttt ccgcccgctg ttttcaaatt cctcttggct
     7801 gcaactgaat gcggtcaagg cagcagttgc catgcaggca acttgcataa ggtttcttaa
     7861 tttcatcata atgaagtccc ccttagtttt ctacggttaa gatgtcattg attaggtctt
     7921 ccaagtcgct gctggatgcc gaattgtagc tatgggtaga ggtgctgccc gaataggagc
     7981 gcgtaatggg atggtaaggt tcgccgcttg ttgcaatgac tccttcattc tccattttga
     8041 taacttcgat agacggagtg atgtatgctt ctctaccgtc tggtgtgttc tgtttcatat
     8101 acacaaatta tttaaaggtt aaacaataaa aaaaacgtga gtaactatgt ttgtatatcc
     8161 tttattcagg ccttcgcatt gccctacaga tgaatataca acagtcaccc acgtcgtttg
     8221 tgtatatacc atccccctga tgggagaaaa ccatataaac atagacgtga gcatccttgt
     8281 tgttatcttc atctgtaatt ttcaaagttg cgaagtttga ataaagaaga taatttcaat
     8341 aatgctctta ctaatatgta aataaaccca ctacgctata gcggatttgt gacaaagata
     8401 attgtttttt gtttaagtgt atctatgttt ctctattttt tttgggaaag gctcacgtct
     8461 ctttcattta taggagttag gagagttatc acttctaact cccgataact ccttcaaata
     8521 tttagtaact gtctgcattg tctttgagga tgtttttctg aggagcatag cggctatgtg
     8581 gcgaataaag aggggaagac agaccgaaaa gaagctgaat aaaatctttt taagcaaaat
     8641 taaaacagag atttgatata ctttaaacag aacaccctgc aaactccggc ttgctctgtc
     8701 cggcagtttg cagggtgtct gcttggtttt ctcgcgtgta cgtagctcct tacgccacga
     8761 acggaagtcg atgccatagc aatttttcat aataagactt tccatatttt tgcaaatgtc
     8821 cgtactgcct ttggctgaaa caatttatat aagtaattga agtttcgtaa gtgagtatgc
     8881 ctgctgataa atgggaattt atcgcacaga gcgcgaagcc tgctctcata acctatggag
     8941 agcacgagtg aaagcttgtg gatttttatc taaaacatag gtattccttt actcttctcc
     9001 ctttgtttgt ctgctgtggc atagggaatt tatgacgcct aacggccatg aacaaccctg
     9061 ctttcgacca taaagcaatc gtttgacgac cgtaagcaga gttgttcatg gccgttaggc
     9121 gtcactaact ccagagctat tacagatgaa gtacgtagcc cgaacctatt gcgcacaagg
     9181 cgcaaacgta ttatacaacg gtgtaaaaga cattagagtg cattattcat agtcggcctt
     9241 tgattcccga taactcctac tatgctccta cagtccaact ccatatccgt tgacttcaca
     9301 gtaaggacaa gcccgaaaat gcaggaaaac cgaacctgcc gattcatgta atctgcatgc
     9361 agtattatgg taggggatag cagcttactg caaaactcag gcgtttcagg caggtggaag
     9421 caaattttgc ttccaccttt tcaggttgct tccaccgcag ggcaaatgcc gatggacagg
     9481 gggatgcagg aggtgggtgg aagtgtggaa gcaaagtgat ggaaaattaa tttggcattc
     9541 acacaataat aaccgtatat ttgtagcatg gctgtctgcc tcctcttaaa ttcagataaa
     9601 gaggaggtag acaaatgctt gctatgagaa acacataaat ggttataacc aagtgatgaa
     9661 acaattaatt gcatgttgcg ggttggattg cgaaaattgc gccgcccgta tagccactgt
     9721 caataatgac gatgagctga gagagaaaac cgccaaagag tggagtgtgc tgaacaatac
     9781 gccggaaatt acgccggaaa ccatccattg tatggggtgc cgtgcagacg gggtgaagtt
     9841 tgcctattgc agcgattatt gtgctatccg caaatgtgtg tacgaaaaag gtttcaatac
     9901 ttgcggtgac tgtaaggaac tggaaacttg ccaggtggta ggtgccgttc ttcagcatgc
     9961 acccggtgca aaggaaaatc tttattaacc gtaaattctt tgattaaata aaatattgct
    10021 tatctttgca gtatgacaaa gacatttaaa tcggatttgg ttttgtaaac aatctgtgtt
    10081 ccatgcacag attgtccctt tcgtttactt tcggataact tctttcgaga gtgtttttct
    10141 attgttataa ttcaagttta atctgcatat tatgctgaag gtgttgtgat actttccgta
    10201 tatgcaaaat atagtaagaa aatgagtaac gaaaataaaa ctatccacga tttcgaattt
    10261 aatttaatct gtgacttttt ctccaatatg gaacggcaag gccctggcag tcctgaagcg
    10321 acgttgaagg cattgagctt tgtagacggt cttaccgatg aatcccttat tgccgatatc
    10381 ggttgtggaa cgggtggtca gacaatggta ttggctggcc atgttccggg acagattacc
    10441 ggaattgacc ttttccccgg ctttattgac atcttcaacc gtaatgcaag gcagttgggc
    10501 ttgcaggaca gagtaaaagg aattgtcggt tcaatggatg ccctcccttt cggtgaggag
    10561 gagctggata tgatttggtg tgaaggtgct atctataaca tcggctttga acgtggcttg
    10621 aaggagtggc gtaaatatct gaaaccggga gggtatattg ccgtatccga gagttcatgg
    10681 tttacggacg aacgtcctgc ggaaatcaat gacttctgga tggacgccta ttctgaaatg
    10741 gatacacttc ccaatcaggt agccaagttg tacaaggcgg gttatctccc cgttgctaca
    10801 ttcattctgc cggagaattg ctggacagag cattactttg cttcaaaggt tgcggcccag
    10861 gagattttcc gtaagaaata tgccggtaat aaaattgccg aagagttcag ctcactccaa
    10921 atgattgagg atgaactata cggcaaatat aaggaattct acggttatgt gttttttatt
    10981 gctaagaagg taggttgatg gcagacttct cttattgagg aatgcgggta ttctcatggc
    11041 agaatatccg cattttgtgt tttgagtgga ttttattgtt ttgaggatgt acggaacttc
    11101 tgaggaggta ttcccgtatg acgtttaaag aatttgttga agaaggccgc attattaaaa
    11161 cctagactca cggctatatc ctttatcgga gtgttggcgg tacaaagttg tgctttggca
    11221 tccatgatga tagtattgtt gatgatttcc atggctgtat atcctgattc ctttttgaca
    11281 aggcggcaaa gagctgccgg tctcatattc attttcaatg cataatagga cacttgatgc
    11341 tcccggacat agtctgtgtg taccaatcgg ataaaaatgc ggtattggtt gaaatgcctg
    11401 ctgcccggag tctcttttat tctagggcgt tccggacaga gttcggatat accttgtaac
    11461 agatatgcca gtagagtttg caatgaaact agacttgagg ggctttctgt tctttggtag
    11521 aggtgtgaca aataggtcat gaactcggca taaagctgga agtccgtttt cgatagagga
    11581 aaaatatagt gtttgcctat aatgtgaaac ttatccatca tgaccttgcc ggcccctgaa
    11641 ctctggataa gttgttggga aaatatgacg acatatattt cagcatcgtc tgacgtgtgt
    11701 agcaattgta cgaaggtctc gggaggaata actaggaggg cgttagcttc aaccctgaat
    11761 tgagtatggt ttatgatagt tttcagaact cctttggtgc atagagcgaa gatactggcc
    11821 ttggtgtggt atggcttttc cactagcgga ttcagttcat tggttgtgat atgattgcag
    11881 gcaatgaact cgtcatttat attgaattcg gatatattca tgttggagat tttaagacgc
    11941 aaaaatgggg gataataatg tataaatgac agaggtaaca gttaaaatca atattacgct
    12001 caacttatct ctgttaaata aggtaaagtt gtgaataata gaatatatac atattaaaat
    12061 ggaatattga tttataaggg tttgtttgtg gtataagcat tttaacccga actttgcttc
    12121 ttgtatgata aaccaattct gatgaatccg aatgttcctc aagaagtacg tataataaat
    12181 gccatctccg agcagttgtt caactcatgg cccgtcagca ttattatgat tgatttggaa
    12241 gattgtatct ggcgtctgaa tcagcaggtg atgaatgaac tccaattgaa tgagcatgtg
    12301 atagggcggc atatcactga cttattggaa gtggtatgtg ataaaaagaa tgtgttggaa
    12361 gcccttttgc tgcaacttcg ggagagggat gtacggatta ttcccttgga taccaattgc
    12421 tttatacgtg aattaaagag tggtatcagt tttctgatac aaggtgctat ggtgggaatt
    12481 catgaagatg gacaattggt gaggattgta ctctatttta ggaatgtgtt ggaagaacgg
    12541 acacagaagc atttgctgaa tattgcgctg agccgcaccc agatatttca atggtctttc
    12601 gacatggaac ataatctgat gattatagaa ccgcgttatt ttgaatattt ggggattcct
    12661 acgcgtgact atacgctgac gcctgaggaa ttcgcatttc tgattcatcc ggacgaccgg
    12721 aagggagtgt ttgatgcttt ggctttacag ttgcatggta atttgtacga acgcccagtg
    12781 gaataccgtc tacggagggg agacggcaag tgggagtggt ttgaggcgca atctacttat
    12841 gtggggcaat tgacggattt gccgttccgt atcatcggta tttgcatgag tacgcagaaa
    12901 tacaaggata cggagaataa attgaacgag gctttgcaga aagcgcaacg tagcgatgag
    12961 ttgaagagcg tatttcttgc taatatgagc cacgagatac gtacgccact aaatgccatt
    13021 gtgggcttct ctacactact ggcttgtggg gatgccgact tgtcgcggca ggagattatg
    13081 gaatttacgt ctttgattga aaagaacagc cagttgttaa tggtgttgat ttcagatatt
    13141 ctggatttgt ccaagataga atcgaacacg atggaattcc attttgagaa ggtttcttta
    13201 aatggcatat tggaaagcat ttacagtgcg cagaagatga atcttcggaa aggagt
//
