LOCUS       c00009_gnlPro..        14756 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MEECLEIL_9.
ACCESSION   c00009_gnlPro..
VERSION     c00009_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 12:27:35
            Original ID  :: gnl|Prokka|MEECLEIL_9
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14756
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14756
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1266:4756]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1267..4756
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14756
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14756
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(2..709)
                     /locus_tag="ctg9_1"
                     /transl_table=11
                     /translation="MNPPHRSSSAHRSAVPAYRKWYFGSGASQSGSTRRVRLSGQPDPD
                     PLPFEAIRIHEERKVGPPSTSADGHSAHGTFTIPEGAEGKKLYGTCSLFLGVDDWGILE
                     VKDSGGNVVAQVDLKENPQTAGEQGGHKYHTGTGGAQLPSGTYSWEVSQTNIDYNPASG
                     NTSICNYSIDVVPTEPGGRKEPEPCPCEGDTCDNSGGTPPSPPQARSCPEAGMESGALG
                     NYSSAGGSGTGGST"
     CDS             complement(1267..2034)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_2"
                     /sec_met_domain="Fer2_3 (E-value: 2.2e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 7.5e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 4.3e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(2075..4033)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 4.2e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.2e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(4055..4756)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg9_4"
                     /sec_met_domain="SucD_FumR (E-value: 2.6e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             complement(4784..4939)
                     /locus_tag="ctg9_5"
                     /transl_table=11
                     /translation="MRKASSSRNRQQNDNHSKLINSNLFPRFFKNPKSAGNSRRGLPSG
                     LEPGIL"
     CDS             4957..5229
                     /locus_tag="ctg9_6"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             5232..6047
                     /locus_tag="ctg9_7"
                     /transl_table=11
                     /translation="MMAFIEPHIHMVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSAD
                     GFRDYFVQLTECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLG
                     IGEIGLNRNTSHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLD
                     PCRVLVDHCEEHTFPLVKEAGYWAGLTLYPTSKLNPKRAGDILELYGMDRVWANSAADW
                     GDSDPLALTALACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(6081..6314)
                     /locus_tag="ctg9_8"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(6746..7453)
                     /locus_tag="ctg9_9"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLTKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYNGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             complement(7484..7573)
                     /locus_tag="ctg9_10"
                     /transl_table=11
                     /translation="MNYKYNILTLNIFNCLRIPNSLFKHKYIH"
     CDS             complement(7999..8247)
                     /locus_tag="ctg9_11"
                     /transl_table=11
                     /translation="VLAVGAAVPPAAYKYVLDVSCIKSITDWLTARKRYVNAASRSRGE
                     PSREEKLNVRLIPAAVVPVLVLQPMTELSEPFSTRKP"
     CDS             8279..8488
                     /locus_tag="ctg9_12"
                     /transl_table=11
                     /translation="LTAPGIRGHYDAEGAPGDSVVITGANGTNTFSLLSPIFTEIRGEM
                     VPEPATVSLGLLGLAALMMRRRRA"
     CDS             complement(8952..9125)
                     /locus_tag="ctg9_13"
                     /transl_table=11
                     /translation="MIIALRTEHVTREALWNYFVPGCNEHYLLHIMRVSPSFIPELDTV
                     AVHGSRIVGKHR"
     CDS             complement(9139..10344)
                     /locus_tag="ctg9_14"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSVLLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAA
                     GASLRMVAIPGGTFLMGSTAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDVMTMHRLWNFSKG
                     EP"
     CDS             complement(10368..11141)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg9_15"
                     /sec_met_domain="adh_short_C2 (E-value: 2.7e-75, bitscore:
                     244.9, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVARRFASEGARVILI
                     SRSPSSCGGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGIT
                     RDSLMLRMKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQA
                     NYAASKAGLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKE
                     QGSVEDIAALTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(11241..11579)
                     /locus_tag="ctg9_16"
                     /transl_table=11
                     /translation="LAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDAL
                     MEKMEKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLAEPDEDGAPPGAL
                     RENEEAGQ"
     CDS             complement(11822..13387)
                     /locus_tag="ctg9_17"
                     /transl_table=11
                     /translation="LFRETEMTINWGERVALVGPNGAGKSTLFRMILGEDTPDEGSISM
                     DEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAENANKTDTPEYAEAIDT
                     FNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYLAKLLVLEPDLLMLDE
                     PTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDIDNEELVEYRGNYSDF
                     LQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQSRIKQLEKMKIIQKPV
                     ACRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVERGERTVLVGPNGAGK
                     STLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVLEEIMKCSAEIREEEA
                     RSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLMDEPTTHLDLLSVEAL
                     VQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYDYYLEKSGILDDEKGG
                     ITAE"
     CDS             13555..14262
                     /locus_tag="ctg9_18"
                     /transl_table=11
                     /translation="MPTTQTFRLLLAAALLCGWSSCCTPPAEDYIQKPYVQQQMSGLAN
                     AFLALLPPDQAALPAAGAEARWLADTAVVQSAAIARDNRTVLFGWLNNILVNSNLRDRG
                     LCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCVYVNAAGKGLQGSIVLDAWKN
                     CGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGMEHHLVWPGWARKRPMLVQRIF
                     QSDQQNEAKAAAE"
ORIGIN
        1 ccgtgcttcc ccccgtcccg ctgccccccg ccgagctgta gtttcccagg gcgccgcttt
       61 ccatgcccgc ctcagggcac gaccgggcct gcggcgggga gggcggcgtt ccgccgctgt
      121 tgtcgcacgt gtctccctcg cagggacacg gttcgggttc tttcctgccc cccggttccg
      181 tcggcaccac gtcgatgctg tagttgcaga tggaggtgtt gccgcttgcc ggattgtagt
      241 cgatgttggt ctggctgact tcccagctgt aggtgccgga ggggagctgc gccccgccag
      301 tccccgtgtg gtatttgtgc ccgccctgtt cgcccgccgt ctgcgggttt tctttcagat
      361 ccacctgcgc caccacgttg ccgccggagt ccttcacctc caggattccc cagtcgtcca
      421 ccccaaggaa gagcgagcag gtgccgtaga gttttttgcc ctccgctcct tccgggatgg
      481 tgaatgtccc gtgcgcgctg tgcccgtccg ccgacgtgct cggcggcccc actttccttt
      541 cctcatggat ccggatcgct tcaaacggca gcggatcggg atccggctgg ccggataagc
      601 gcacgcggcg agtagagccg gattggctgg caccggaacc aaagtaccat ttccggtaag
      661 cgggaacggc agaacgatgg gcggaggagg aacgatgagg cggattcatc aggtattcaa
      721 gagttgggag taatgaatga agcgaggggt ggccgccctt tcctgatcgt tttatcaata
      781 gtatgatccg aagtcggtgt cgatagaatt ttatttgtat gtttttgatt ttttataaaa
      841 gatggtcatt attttacacg aaaagataat attataattc ttacgttcag tgcattccct
      901 taatagacat caatgttgtc tgtttgttag aaaatgtttc cctctcatgc tgagcccttg
      961 acaggatgcc atcccttccg ggcatcagtc taattcctgt aatcaatgtt tctttctctc
     1021 gaagaaagat gggggccgtc gctgtcggaa gggggcttgc ttaggtttcg tccggcattt
     1081 ccaagtacag tctcctggat tactgggaac cttccagtgt aacatttatt ttttacgctg
     1141 cgcgacgatg aggaagcaac tgtctgatat tttattcctg gttcaaggaa acctgataat
     1201 gaaaaaaact cccgacagcc gatgccgccg ggagttttta cagagcgtct taagaaggaa
     1261 tcttctttag aaacagagac cttccttggc gttggctcgc atgaagtcgc ggttgaggcg
     1321 ggcgatgttg tccacgctga tgcctttcgg gcaagcagct tcacattcat actggttcgt
     1381 gcagttgccg aagccttccg cttccatttg cttcatcatg gccaggacgc gcttggaacg
     1441 ttccggctgg ccctgcggca gcagattgag atgggcgatc ttggcggagg tgaacagcat
     1501 ggcggaggcg tttttacagg aggccacgca ggcgccgcag ccgatgcagg cggccgcgtc
     1561 aaaggcggcg tccgccttca ctttttccac ggcgatgttg ttggcgttcg gcgcggaacc
     1621 ggtacgcacg tcaatatagc ctccggcggc gatgatgcgg tccagggcgg agcggtccac
     1681 catcaggtcc cgcaggattg ggaaagcctt cgcgcggaag ggttcaatcc agacggtatc
     1741 gccgtccttg aacttgcgca tgtgaagctg gcaagtggtc acctggcgtt ccggcccgtg
     1801 gggaatgccg ttgatggtca gggagcacat gccgcagatg ccttcccggc agtcgtggtc
     1861 aaaatggatg ggttccttgc cttccttgac caggccttca ttgacgatgt ccagcatttc
     1921 caggaaggag gcgtccaccg gaatgtcctt ggcggcatag gtctcaatgc ggcccttggc
     1981 ttcccggttt tcctggcgcc agaccttgag agtgagattg agtgttttag ccatgttata
     2041 atctttcttt tgagtgttaa tgtattggct atctttactt gtagctgcgg atggcaaggt
     2101 gcacgttctc gaaggtcagc ggttccttgt ggagaacagg caggctgtcc acgccagtgt
     2161 attcccaggc ggctacatag gcgtattcat cgtcgttgcg cttggcttcg ccgtccggca
     2221 gctggtattc cacgcggaag tgggcgccgc aggattcctg gcggttcagg gcgtcatagc
     2281 agagcagctg ggcgaattcc aggaagtcgg ccacgcggca ggctttttcc agttccgcgt
     2341 tgatgccgtc cgccgtgccg gttacgcgca cgttttccca gaattccttg cggagctggg
     2401 gaatgcgttc aatggcgtgg gtcaggcttt cttccgtgcg ggccatgccg cagtcttccc
     2461 acatgatgag gcccagttcc cggtggaagg agtccaccgt cttggtgccc ttcacattca
     2521 ggagcttgtt gatgcgttcc ttcacttcgt cttccgcagc cttgaattcc ggggcggcgg
     2581 tggtgacggc accgggcttg gtggtcgtca ggtaagcggg cagcgtggcg ggaatgacga
     2641 agtagccgtc agacaggccc tgcatcaggg cggaggctcc caggcggttg gcgccgtggt
     2701 cggagaagtt ggcttcaccg aggacgtgca accccttcac gttggacatg aggttgtagt
     2761 ccacccacag gccgcccatg gtgtagtggg aggcggggta gatcatcatg ggcgtttcat
     2821 gggggtcgtc gtccgtgatt tcttcgtaca tgtcaaacag attgccgtat tggccgtcaa
     2881 tccattcgcg gcccatgcgc ttgatttcat ccgcaaaatc caggaagacg cccttgccgg
     2941 tgacggccac gccgcggccg tcgtcgcagg cttccttggc ggcgcgggag gaaatgtcgc
     3001 gcggagccag gttgccgaag gagggatact tgcgttccag gtagtagtcc cgttcttctt
     3061 cgggaacatc ggaaggcttg atttccttct tacggatttt ttctgcggtt tcacgggact
     3121 tgggcaccca gatgcggccg ctgttgcgga gggattccga catcagcgtc agtttggact
     3181 ggtagtcgcc tttgaccgga atgcaggtgg ggtggatttg cgtgaagcag gggttggcga
     3241 agaaggcacc acgcttgtag gctttgtagg cggcagtgac gttgcaaccc atcgcgttgg
     3301 tggacaggaa gaacacgttg ccgtagccgc ccgtgcagag caggacggta tcccctgcgt
     3361 aggatttgat ttcgccggta accagattgc gggtgacgat gcccttggct tcgccgtcca
     3421 ccagcaccag atccatcatt tcatggcggg agaacatttc aatgtgtccc ttggccactt
     3481 ccttttccag ggcctggtag gcacccagca ggagctgctg gcccgtctgt ccgcgtgcgt
     3541 agaaggttcg cttgagctgg gcgccgccga aggagcggtt gtccagcagg ccgccgtatt
     3601 cacggccgaa gggaacgccc tgggccacac actggtcaat gatgttggag gagacttccg
     3661 ccagacggta gacattggct tcacgggcgc ggaagtcgcc gcctttaacg gtgtcgtaaa
     3721 acaggcggta aacggagtcg ccgtcgttct ggtagttctt ggccgcgtta atgccgccct
     3781 gggccgcaat ggagtgggcg cggcgggggc tgtcctggta gcagaagcat ttgacgttgt
     3841 agccaagttc ggcaagcgtg gcggcagcgg aggcgccagc caggccggaa cctaccacaa
     3901 gtaccgtgta cttgcgcttg ttgttcggat tgatcagttt ggactcaagt ttgtatttgg
     3961 accatttgtc ctgaataggg ccggagggaa ttttggcatc cggcatccag tcgcttacgg
     4021 gaaaattaat catgactttg agaggagttg atggttattt gatgataccc agaagaaccg
     4081 agaccggcac ggagatgaag cccaggcaga taatcgcgcc gtaggcgatg gcgataaagt
     4141 tgtagaaggg ccggattttg cgggaatcga cgcccacagt ctggaagatg gactgtaccc
     4201 cgtggcgcag atggctgaac agcatcagaa cggccaggat gtagaaggcg gagcaccata
     4261 cgttggagaa tccggtcacg atcatcttgt acacgtcaaa ggtttccacc gtaccgtcgg
     4321 aaatgaaggt ggtgaactgg gcggggtcgt atcccacgcg cagggtgtac tggtacaggt
     4381 ggtagatcag gaacaccagg acggtcaaac cggtatagat catgtagcgg gaggagagcg
     4441 ttgccttaat ggtgttcttg aacacgtagg gttcgcgggc cgcatggttt tccagcttca
     4501 gctggatggt cagccagacg tggatgatga agatcaccgc aagccccgcg cggattcccc
     4561 agagggctgc ttccggcatg gagtgcaggc cgtgggcgta ggtgttgatc cattcagggc
     4621 ctccgaagat gagaaggttg cctgccaggt gtcccgcaag gaacaagacc aaacataacc
     4681 ccgtcagagc cacaatgatt ttgcggccga tggaggatgt cacgaatgta catatggttt
     4741 ttactagtgc attcataggc gctctaatga aataaatgcg tcttcacagg atgcccggtt
     4801 caagcccgga tggcaagcct cttcttgaat ttccggcgct tttcggattt ttgaaaaacc
     4861 ggggaaagag gttgctgttt atcagtttgg aatggttatc attttgttgc ctgttccggc
     4921 ttgacgaggc tttccgcata ggcgtatcgt ctgtgcatga aaagaagtaa aaaggaggtg
     4981 ctggacgcgg atttcgcagc ggcgcgcgcc ggcgttctgg atgtggccgc atttctggac
     5041 cgggtggacc gcggggaagg ggaggcggat ttccgctacc atgccctgat ggatgttctt
     5101 cccctcttgt ccgcatccgg ccccggacgc gtccgggcca ttctggaagc cctttcctac
     5161 agggatgaca ccgtgccgga aaccgccgca gccaaagcgg cctgcggagc cccgaacctc
     5221 agcaaataag aatgatggct ttcatagaac ctcatataca tatggtgtgc cgcaccacgg
     5281 acgaataccg ggccatggcg caggccggct gcctggcggt aggggaaccg gcgttctggg
     5341 ccggttacga ccgttcgtcc gcggacggtt tccgggatta tttcgtacag cttacggaat
     5401 gcgaacccgc cagggcggcc aagttcggca tggaccatta cacatggctg tgcatcaatc
     5461 ccaaggaggc gcaggacgtg gctttcgcgc gggatgtgat gaaactgatt ccggagttca
     5521 ttgaccggcc caatgtcctc ggcatcgggg aaatagggct gaaccggaat acttcccatg
     5581 aaatgactat ttttgaagag catctggatc tggcggtgcg cctcaaccag cttgtgctga
     5641 ttcacactcc ccatctggaa gacaagctta aggggaccgt aatgattctt tccgccctga
     5701 aaaaccgtcc ggatctggac ccttgccgcg tgctggtgga tcactgtgag gaacatacct
     5761 tcccgctggt gaaggaggcc ggttactggg ccgggctgac cctttatccc accagtaagc
     5821 tgaatcccaa gcgggcgggg gatattctgg aattgtacgg aatggaccgt gtctgggcca
     5881 attccgcggc ggactggggg gattccgatc ccctggcgct gacggccctg gcctgcgagc
     5941 tgcgcaggcg cggtttttcc cggcaggaaa cggaacgtct tctcctggaa aatccggaga
     6001 cattcatggg acagtccccg aagttccgga aagtgtcgtc ccgctaattc cgcccgaggc
     6061 gcggcggagg gtacggccct ctagtccccg tccgggaaaa agacggtgag gacggcgccc
     6121 aggatgaccg ccgcgtcatc cagaaggccc agcctgccga ttccgtcaaa caggaattcg
     6181 tcgggagtca ggatgtaggc gccggcggcg gccagaaggc atatattccg tttgttgaaa
     6241 aaacgcggtt ctccttttct gcttttgaaa taccggaaca ggcgcagtag cagctgctgt
     6301 ttttgaaggt tcatggacgg gaacggggga taaaggttca agctcggcca ttttcccact
     6361 ccttttccct gtttcgggga aggagtctgt tgccgacgga cggaaaccgc agcgatccgg
     6421 accgtgcggg gaaatggatt gctgaaagga tgggctgttc cggatgctga gggaagccgg
     6481 gctttgcatg ctccggttcc ggctgtcccg gcatgggaaa aaggggcgtg tacggaagtg
     6541 gggcggggcc ggaagctctt gaaatgaccc tcccggggga gcctgaatgc catttccccg
     6601 tcaagtgctg gccgtgaggg taccgcagca aatggaagct tcttcccccc tgttttttcc
     6661 ggcagatgtt tgaacggata aggaaaaggc cggctcacga ttttgtgagc cggcctttga
     6721 atatagggag gcggacggta caggcttatg ccctgcggcg gcgcatcatc agcgcggcca
     6781 gtcccagcag gcccagggaa gccgtggcgg gttccgggat gctggcgatt tcactcatca
     6841 gttgaccaac ttgttcctgg gaaaggaggg agtcgtggat gtagagctgt tcgatggatt
     6901 cagccagtcc tgcgtccatg agaatctgat caatttgctg gttgccgaat ttcaggccgc
     6961 tgttggaata gtacgtagcg ctgtctccaa aatagatgcg ggtgccaaga tctccggtga
     7021 ctacggaaat ggtcagggaa ccttccgtgc ccagcggggt gtcaacgacg ggcccgttgt
     7081 atgaggtgtt gttccataat ccctggagtt tccggtccgt gttcaggccc acgccccagc
     7141 ttacactgct gtttttggcg ttaaacagag cggtataggc gtccggagtg ttgattttgg
     7201 tcaggtcaag aaccatcgtc acagacataa cgtcgcggtt gttggcaccg tatccgttga
     7261 aggttatccc ggataacgtc agattgctgt cgtcagacgt gatggaaacg gaatctttca
     7321 gggtgccgaa atccgccgtt tgggaggcaa agtccgaata tcccacgatg gagctatcca
     7381 gcagagaggt agccgcggta gcgcttaggc tcatgccggc cgaaagaatc agggtggata
     7441 ataatttatt catggtcagt atcttaataa aatgatgcaa gattcaatgt atgtacttgt
     7501 gcttgaataa cgaatttgga atccgcaagc aattaaaaat attaagagtt agtatattgt
     7561 atttataatt cattgaaaat aatgattttt taatatctct ggtccttttg ctaagatgac
     7621 gggtcagtct ttgttattca ttggtttcat gattgatttg gcctcttttt cattacttga
     7681 cggattccaa atccgattgg ggaattccaa attcgctaca agttgccatc caaaaggaat
     7741 aataaatatg aagaaaacac tgacattttt aatcgcgatg ggaagctttg ctgtttcctc
     7801 ggaggcagcg accgttttta attattacac tcccggtacg gataattaca atagtaccat
     7861 ccatgggttt tatcttggcc tggggtcttc ttccctggct ccttccgatt cctcttctcc
     7921 ctcctccctg tccggagaga tcagactgga cagttttacg ctgcgcggag ccgccaacgg
     7981 tttgggcgct aatgtcactt acggcttcct ggtgctgaat ggctccgaca attcggtcat
     8041 cggctggagc accaatacgg gaactactgc agcagggatt aatctgacgt tcagtttttc
     8101 ttccctggat ggttctcccc tgcttcttga cgcggcattg acataccgtt tcctggccgt
     8161 gagccagtcc gtgatggact tgatgcagga tacgtctaaa acgtatttat atgctgcggg
     8221 gggaacagcc gcccctactg ctaacacgga aggagatacc gtaacgatca gcggcggatt
     8281 gactgctccc ggcatccgcg gccattatga cgccgaggga gcgcctggtg attctgtcgt
     8341 tattacggga gccaacggaa ccaatacttt cagcttatta tccccgattt tcacggaaat
     8401 ccgaggggaa atggtgccgg aaccagccac ggtttccctg ggcctgctgg gactggccgc
     8461 gctgatgatg cgccgccgca gggcttgagc ttcctgatgg cgaaaaatcg gcggatgaga
     8521 gctgttcttg cggaacagct cttgtttttt atatccagag aggaagaatt gcttatccgt
     8581 atgcgggatt catgccctcc ggaaggtacg gaatttccgg gggcaggggg ccgtatccgg
     8641 ttttttccgc atggcggcaa tttgctggaa acgtttttga gacgcagtac cggaaagctt
     8701 tttctttacc ggaaaatgcc gtcaaattcg gcagcgcgct tttcgtccat atggtacaca
     8761 gtagctttca catagcggcc tttcaggccg gatagggacc ccctttgcag ctcacagacc
     8821 tggagggccg ccgcatacat attattcgcc gtcctattcc ccggcgctgg tatttcggaa
     8881 gaacggcaat gggccccatg cccagcactt catattcttt tccatcgtct gccctgatga
     8941 cggacgttgc atcaacgatg tttcccgacg atgcggctgc cgtggacggc gactgtatcc
     9001 agctccggga tgaaggaagg actgacgcgc atgatatgga gcaggtaatg ttcattgcag
     9061 ccggggacga aatagttcca gagcgcttct ctcgtgacat gttccgttct taatgcaatg
     9121 atcatgaagg gttgttcttt acggctcccc cttggagaaa ttccagaggc ggtgcatcgt
     9181 cataacgtcc ggaatgttca tggggcgcac cacgcggaac ccgatcatgc ctccgtccgt
     9241 caggtaccag atgcttttag ggttttgagg atcctgacgg ttccaggcag gggtgctggc
     9301 gcggcgcgca gcgcttctca ggctgtccgg gtcgtcttcc cacgaaccgc cgcgaacgat
     9361 gtgaggggcg ccggggatga tgaccagggg gtctttcgcg ggcaagccgc tccgtttgcc
     9421 gtaggcatcc ggaacgtaag agtccaaaac ccattccgcc acatttccgt gcatgtcccg
     9481 gagtccccac ttatttggtt ttttagagcc tgttttctgg tagcggtcat tggagttgtt
     9541 ccagtaccag gcgtactggt ccagagaggc ttccccgttt ccgtaagaat aggcgccggg
     9601 ggagccggcc cggcaggcgt attcccattc cgcctccgtg ggcaggcggt agtaatgccc
     9661 ggtctgggcg ctcagccatt cgcagaattt gctggcggcg tggtgggaca tggagatggc
     9721 gggcagaccg tgttcatagc cgtgacccat gcccaggttc atggcggtgt agggggcggt
     9781 aggctgcgta acggagtccc acagttcgtc atccggctgt tcctccagaa gctgaccgtc
     9841 cttggcgcgc ggacgcccgt tttccatgaa ggccgtataa agttcccagg ggatttccgt
     9901 ttccgagatc cagaagggag agatgctcac tttatgctgc ggtccttcgt ccggtttccg
     9961 gtgcggctct tccgcggtac tccccatgag gaacgttcct cccggtatgg cgaccatgcg
    10021 cagggaagct cccgccgcgg gaaccgtttc cgtgtaggat tcaaaacgtg ccggatttcc
    10081 ggaagcttca atgagctgat ggatttggcg cgtcgtgccg accagctccc gggacggcag
    10141 gtcatccgga atgggaaggg caggaccggc agcgcggtcc agttcccgtt tttgcagcgc
    10201 ggatcggctt tctccccact ggcgtgcgct ggtaatgcgc gcggcatctt ccgtggccgg
    10261 gcggggggaa ttattttctt cccggcaccc ggccagcagg acgcttcctc ccagaaagca
    10321 ggaaacaagg aaaatgccgc gcatggaatg gtgaaaaccg gaatgcccta catcgtcatg
    10381 cctccgtcgc aggcaatgac ctgcccggtg atgtaacggg catcgtcaga ggcaaggaag
    10441 gccgtcaggg cggcgatatc ttccacggaa ccttgttctt tcaaaggtat tttcttaacg
    10501 atttcttcct tgagattgtc gggaatggca ttggacattt ccgtggagat gaagccggga
    10561 gcaatggcgt tgcacgtgac tttgcgcgga gcgaattcct gagccagtga tttggtgaaa
    10621 ccgatgaggc ccgccttgga agcggcgtaa ttggcctggc cgatgttgcc gacgagaccg
    10681 atgacggagc tcatgttgat gatgcgcccg gccggggatt tcatgagaac gcgctggagg
    10741 gccttgaccg tattgaacgc gcttttcagg ttggtgtcca gaacggcatc ccagtcttcc
    10801 tctttcatgc ggagcatcag ggagtcccgc gtgatgccgg cgttgttcac caggatgtca
    10861 atctgcggga agtctttcaa aatggcggcc atggtttcct gaacggccgc gtaatccgct
    10921 acgtcgcagg ggtaggcctt gcaggaatcc ggaaattcct tgttgatttc ttctgcggcc
    10981 cccccgcagc tggatggact gcggctgatc aggatgaccc tggctccttc cgaagcgaag
    11041 cggcgcgcga cggcattgcc gattccgcgg cccgcgccgg taacgatggc tgttttacct
    11101 gctaactttt gcatgctgcc cacagtaaac ccgtttttca cggttccggc aagcttgaaa
    11161 tggacttggc cgcgcaggaa cccatacggg gaaagggcgt gccgggaatg aaaaaagggg
    11221 gggagaaacg gggcgggggg ctactgtccg gcctcttcat tttcccggag tgcaccgggg
    11281 ggcgcaccgt cttcatccgg ttctgccagg tcgctgaatt catccgaatt ttccaaaatg
    11341 tcctttaagg cggcggaacc gtaatagcgg gcctcaaaca ggcgtttgcc ttcctgcctg
    11401 cagcggttgt ccagcatttc cattcgtttt tccatttttt ccatcagggc gtcttctttc
    11461 tccttttccg catcgttcaa tttatcctga agctggagga aatgccggat gtccttctga
    11521 atgtcctgca gcgttttgac ggcgttgtcc gcgctttcct tgtcctgaac gcctgccaac
    11581 gtctgctgga tattgatggc aaaggaaaag gcctggttga tcagggattc cgcggaagga
    11641 attttttccg ccggagccgc tgctgcgggg gaagccgttc cggcggccgt ttcaccaaat
    11701 gcaagagagg ctccggacag aagcgcagaa tataagagag gaacaagaaa agccttcatc
    11761 ctgttctttt aaggcaggat gaaatccacg gcaaggaaaa aggggaaact gaaaaagagc
    11821 cttattccgc cgtgatgccg cctttttcat cgtccagaat gcctgacttt tccagatagt
    11881 agtcatatcc gcctgcgtag gcggtgatgg tcccccggtt cacatgcagg gttttttgtg
    11941 ccagggaacg gatgaagtgc acatcgtggg agatgaagac cagtgttcct tcataatgct
    12001 tcagagcctg caccagggct tctacggaca aaaggtccag gtgggtggtc ggctcgtcca
    12061 tcagcaggag gttgggcgga tccaccagga atttgaccag gctgagccgc gatttttccc
    12121 cgccggaaag aacgctgacg cgtttttcca catccagcct ccggaacagg aaggaaccca
    12181 ggatggaacg cgcttcttcc tcccggattt cagcgctgca tttcatgatt tcctccagca
    12241 cggtattttc cgggttcagg ttttccgttc gcgcctggga gaagtagccg atgcgcgtcg
    12301 tggtaccggg agtgcgttgt ccggagtcaa tggggatgat gcccgccagg attttgagaa
    12361 gagtggattt gcccgcgccg ttcgggccta caagaacagt gcgctccccg cgttccacca
    12421 gcaggtccaa attttcataa accctgcggt cgccatagga ttggcagact ttttccagct
    12481 caatgacttt ctgggtgctg cgcggaggct gggggaagtt gaatttaaat actttcctgc
    12541 aggctaccgg tttttgaatg attttcatct tttccagctg cttgatgcgg ctctggactt
    12601 gcccggcttt ggaattgatg gagcggaaac ggtcaataaa ttcctgaatg tgcgctattt
    12661 ccttctgctg gttgcggtag gccgcctgaa gctgctcgaa gcgcacgtcc ttttgttgga
    12721 ggaagtccga gtaattgccg cggtattcca ccagttcttc gttgtcgatg tcgtacacgc
    12781 tttccaccag ctcatccatg aaatcccggt cgtgggaaat catcaggatg gctccggggt
    12841 agtttttcag gtatcgctgg agccacagca gggacaggag gtccaggtgg ttagtaggtt
    12901 cgtccagcat caggaggtcc ggctccagga caaggagctt ggccaggtac gcgcgcataa
    12961 tccagccgcc ggacatttcc cgggcggggc ggtggaagtc gctttcccga aaggccagcc
    13021 ctttgagaat tttcttggct ttgggctcca gctggtaacc gttggcggcg ttgaaggtgt
    13081 caatggcttc cgcgtattcc ggcgtatccg ttttgttggc gttttccgcc gtccggatgg
    13141 tgtggatggc ctgttccatt tccggcgtga tgcccagggc gatttccagg acggtttcat
    13201 ccttcggttc gctggcttcc tggggaagat agcccacgat ggcgtattca tccatgctga
    13261 tggagccttc gtccggcgtg tcttctccca gaatcatgcg gaacagggtg gatttgcctg
    13321 ctccgttggg gccaaccaga gccacccgtt ccccccagtt aatggtcatt tccgtttccc
    13381 tgaacaaggt ccgtccggcg tgggattttg tgagattttt gatcgtcagc atggtgaaga
    13441 gaggatgtat tctaccggga tggaaagggg aaggcaagag ccgtcagggc ggaggcaggc
    13501 atttttgaaa gctttactgg atttttacgc gtagtctgct agccttggcg cgccatgccg
    13561 accacgcaga cattcaggct tttgcttgct gccgcccttt tgtgcggatg gagttcctgc
    13621 tgtactcctc cggcggagga ttatatacaa aaaccttacg tgcagcagca aatgtccggg
    13681 ctggctaatg ccttcctggc gctgctgccg ccggatcagg ccgctcttcc cgctgccgga
    13741 gcggaggcca ggtggctggc ggacacggcc gtggtccagt ccgccgcgat tgcccgggac
    13801 aacaggactg tgctgtttgg ctggctgaac aatattctgg tcaattccaa cctgcgcgac
    13861 agggggctgt gctggcaggt ccagcaggat ttgtaccggg acctgcgccg ccgccccgtg
    13921 aagtatttcc gcatagggct gacgattcga gaccgtggaa cgggcaggga gcacagttgc
    13981 gtgtatgtca atgccgcggg gaagggattg cagggctcca ttgttctgga tgcctggaag
    14041 aactgcgggc atctggtgac gctgacccag aaggaccggg aaggcggcaa atgggaggag
    14101 gactggcggg aaccatttgt ttccaaggcc tttccggagg gccattccta cggcatggaa
    14161 catcacctgg tctggcccgg gtgggccagg aaacgcccca tgctggttca gcggatattc
    14221 cagtccgatc agcagaatga ggcgaaggcg gccgctgaat aaaggggaag cctgatccgg
    14281 caggaatcgg cacacggtgc tgcaccgcgg cggtttgcgg tatccgccgt ttttaaggaa
    14341 aatcccggcg aatcggcaaa tggcggaggg aatccggact cagggcaaat aaaaacgcac
    14401 tcagtgcgta caccgagtgc ggattaattg gataatttgc tagtgttgca gggcaaaacc
    14461 ccgctgcaaa cttacttgcc cttggcctgc acaaccggag cgggagcagg agcggtggtt
    14521 tgctgttgct gctgctgctg ggagcaagaa gcgaccaggc aagcggcgcc ggcgatggcg
    14581 aggatagcga tgttcttcat aattcgaatt aaatacagtg tttgttaact actggaacct
    14641 ccgcatccac ggaggtttgc tggcaccaat gtaaatggtg gcaagtagaa atcaagagat
    14701 tttcttgttc catgtcacgg cattacagaa aagagcagga cccccggttt ctgaag
//
