LOCUS       gnlProkkaJEHBGMHF_38   14391 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JEHBGMHF_38.
ACCESSION   gnlProkkaJEHBGMHF_38
VERSION     gnlProkkaJEHBGMHF_38
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 08:13:10
            Original ID  :: gnl|Prokka|JEHBGMHF_38
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 16488
            Orig. end    :: 30879
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14391
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:10273]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..10273
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..14391
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14391
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="1"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             824..1009
                     /locus_tag="ctg38_13"
                     /transl_table=11
                     /translation="MKTNAAAKKRFTFTGTGKIKRKHAYHSHILTKKTTKQKRNLCYSG
                     TVSAADEAKIKNLLVK"
     CDS             complement(949..1131)
                     /locus_tag="ctg38_14"
                     /transl_table=11
                     /translation="MTRQRLLNVAYCKVFGGLPAIRFSRILWGWFVPINKMLRVNYLTS
                     RFLILASSAAETVPE"
     CDS             1152..1445
                     /locus_tag="ctg38_15"
                     /transl_table=11
                     /translation="MKLAKGNFGSRGNVWTVAKNTVEKGLCYAYAHRALKKRTFRSLWI
                     TRINAAVRAQGMTYSQFIGKLNAKGIVLNRKVMADLAMNEPKAFEAIVKAVK"
     CDS             1545..1727
                     /locus_tag="ctg38_16"
                     /transl_table=11
                     /translation="MKHMTLLLTTASSRLHAFSGTESDNRDLGTGALKLHTDGRQFRLW
                     SDKARMGFILPKLGF"
     CDS             1744..2952
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 255.2; E-value: 1.7e-77)"
                     /gene_kind="transport"
                     /locus_tag="ctg38_17"
                     /transl_table=11
                     /translation="MESWKKTFAVIWSGQLASILSSEVVAYSIIFWMSLETGSAEVLAL
                     AAIAGMLPQSLLGPLVGVYVDRWDRKRTMILADSFIALCTLALTALFWLGAARMWHIYI
                     LLACRSAGSAFHIPAMQASVPLLAPASQLTRIAGVNQIIASLSSIAGPALGALLINLTS
                     IGNILLLDVAGAAIACISLLCVRIPNPARDTTRKPDLWREFREGFSAMHAIPGMGWFFT
                     LAIVVWFFIMPVGVMFPLMTLQHFGGGAFEMSLIEIVWGGGALVGGAVMGARTYRVSRI
                     VLVNLMYLVVGLSFALSGLLSPAGFLWFALFTAAAGISSSVFNASFVSVVQTRIEAGML
                     GRVMSLYRSFGLLPAALGLLGTGFLAENVGLTTTFVVAGTIIVAVGAAGFFIPSVMRLD
                     RNP"
     CDS             complement(3042..3914)
                     /locus_tag="ctg38_18"
                     /transl_table=11
                     /translation="MLPVQPGMYIYQLATDQDKLAMRPANAALRLAMLLAEADKQGEDV
                     LSADLKEIVVKKGDASIKVWETLFGAHTKLERQGEDYLITYSDEAQLPDRFFMAGSVLV
                     KTNGTKVLNQSSYSAPWTVEMQDLKVFAYTNTGLRSAFNFDGGETTLYFDGADSYIIGA
                     SSFRIHLDNVDASSNWTGRYTLRAEDSSLAYSLCSGKDFKVEGGASGPTLYSSDMTQAV
                     GMGYELTNGVYRGMQIISGTQECRFLSPLEYDTTKYPASSVTYEWSYDSSTNTVFQKIR
                     YNGYVYPKD"
     CDS             4375..5097
                     /locus_tag="ctg38_19"
                     /transl_table=11
                     /translation="MSLLSIFGCGRAKTPEYPADRLSARDGTEFTITFFKHASLAISVG
                     GKYIYVDPVSANADYGALPKADVVLITHSHYDHLDVAAVEKLLAADTEILCDRTSAEAF
                     EMNCYTMHPGSVATPRDYVKVEAVAAYNTTPGHLQFHPREREDCGYVLTIGGTRIYIAG
                     DTEPTPELQALRKIDIAFLPVNQPYTMTVDQAVEAVKALKPAIFYPYHYGEVDEKTDID
                     RLVRELEGVTEVRIRPME"
     CDS             complement(5164..5571)
                     /locus_tag="ctg38_20"
                     /transl_table=11
                     /translation="MNFIMVPLVTGIVTLGIYKFFELLICRRERREIIGKLEPGSLIDY
                     LKLVPMGLRTGATIRTASETAPGIPAGALKAGCLLLGLGAGLLFGFMLTRITEIQSYDT
                     RSAVYGGSVLVFGGLGLIVSFIVERVLSRRR"
     CDS             5634..6275
                     /gene_functions="regulatory (smcogs) SMCOG1032:RNA
                     polymerase, sigma-24 subunit, ECF subfamily (Score: 123.1;
                     E-value: 1.6e-37)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg38_21"
                     /transl_table=11
                     /translation="MCKKVTDDGKTRLTCNLFRRGASNGITMQTEEQELIRRIAGGETR
                     LCARLVDRYGRAVYTLAARIAGCTEDAEELTQDIFLKAFSSLDRFGGRSSFSTWLYRIA
                     YNTAVSHARRTRPKHYGIDERRLAALPDSEADRLEEWAEKQERLDALNRAVERLDPEER
                     ALVTLFYYEDRSVGECAAITELSEGNVKVQLHRIRKKLYVLVNDEMNGTE"
     CDS             6262..6654
                     /locus_tag="ctg38_22"
                     /transl_table=11
                     /translation="MEQSDAIRRAVRQVPPPELPAGFTPRLMERMRRETLRRERRETWL
                     LTAGGAGCFAALIAACVTTLWPDFRLRITDFALPRPELPHFTLPHFALSEEDKWLVAMC
                     VCIALVFLALLLADLVIRRRIASSRN"
     CDS             complement(6712..7026)
                     /locus_tag="ctg38_23"
                     /transl_table=11
                     /translation="MKKILMICLALVMGLGMCAAAGKPAQKKEVTTVFVTDIDCEHCVK
                     KIMNNVPSLGKGIKDVKVDLPKKEVTVIYDASKNNDENIVKGFATIKVKAEPKKAPAKK
                     "
     CDS             complement(7142..9427)
                     /gene_functions="transport (smcogs)
                     SMCOG1082:TonB-dependent siderophore receptor family
                     (Score: 69.3; E-value: 5.5e-21)"
                     /gene_kind="transport"
                     /locus_tag="ctg38_24"
                     /transl_table=11
                     /translation="MVRDAENQPLVGASVYWAGTTIGASTDAQGAFLLHCVKGYDKLVA
                     SYLGFVNDTLDVKNGVDKVAFALRSEGVALEGVVVEGNLSGNFVKRDGIVKGEMISFAG
                     LCKMACCNLAESFENSASVTVGYSDAISGARQIKMLGLAGTYTQILDENRPIMRGLSAP
                     YGLSYTPGMWLNSIQVSKGVASVTAGHEAITGQINLEHRKPTDDERLFVNLYLDDELRP
                     EANISTAFPVTKDKKLSSVILLHGSMDTDARKMDHNHDGFRDLPKSDQINVANKWLYAA
                     DNGTQVRWGWKFVQENRLGGMLDYKNTRTMREAMEKDWDWRAGDKKMPLYGSHIRNRNA
                     NGYFKVGMPVGPAVYDPDEQDEMRSNLAFVADFDHFSEDAYFGLNDYTGNQNSLALNLM
                     YNHYFTYRSSLIVGVQGHLDYYREKLLNPTPWIAANSVRNYDFDRNEREAGAYAEYTYA
                     IKDKFSIVAGLRGDYNHYYDRFFLTPRGHLKWNITPSTTLRASGGLGYRSTNVITDNIG
                     VLATGRAITFLDNESGKFDFRKFDRMEKALTVGGSLTQTFGLVNPGDATLSFDYFRTQF
                     YNSVVADQEMYADRIVFYNTDGRSYTDTYQIDFSWSPVERLDIFATFRYTDSEMTIRRA
                     DGGTARVERPLVSQYKTLLNIQYATKFRRWVFDATAQLNGPARIPTQTGDLDDSYYSPR
                     YPMFFAQVSRKVGKFDIYAGCENIADYRQKDPILNAQDPYDYKFNSMNVWGPLMGRKFY
                     VGLRFNLY"
     CDS             complement(9575..10000)
                     /locus_tag="ctg38_25"
                     /transl_table=11
                     /translation="MKLKRSISLLLLAVYLFATAGTALASLTCKCVAMKARTEHACCCH
                     CLHVADLPAAAGGEMRAPCCGNHHSTEIELYVSSSFDNNERYTRCIVLDLPPALAAECP
                     CPAHVPFLREKVAERRTPFVREASACSVGFRAPPVLV"
     CDS             complement(10001..10273)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Stand_Alone_Lasso_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PF05402"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_26"
                     /sec_met_domain="PF05402 (E-value: 2.1e-16, bitscore: 51.0,
                     seeds: 461, tool: rule-based-clusters)"
                     /sec_met_domain="Stand_Alone_Lasso_RRE (E-value: 3.2e-09,
                     bitscore: 27.7, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIREEFKVREMAGEHVIVMPGRGGAADMTRIVSLNPSSMYLWEK
                     LRGREFTAADAALLLTERYEVDADTARKDAGRWIASLAECGIVEE"
     CDS             10392..12395
                     /gene_functions="other (smcogs) SMCOG1122:ATP-dependent RNA
                     helicase (Score: 295.8; E-value: 1e-89)"
                     /gene_kind="other"
                     /locus_tag="ctg38_27"
                     /transl_table=11
                     /translation="MKPAPDRIYDTLKRYWGFTEFRPVQLEIIRSVLEGRDTLALMPTG
                     GGKSLTYQVPTLAREGLCIVVTPLIALMKDQVDRLRARAVPAVAIHSGLSPRQIDIALD
                     NCAYGDVKFLYVAPERLATEAFRLRVVRMNVQLIAVDEAHCISQWGYDFRPSYLRIAEL
                     REKLPGVPVLALTASATKTVADDIMRHLKFPEPHILRSSFARPNLSYSVRRTDDKNGQL
                     LRLVRNVPGTGIVYVRTREGTEQIADLLRQEGTTAAAYHGGLGHAERSLRQEEWLSGKT
                     RVMVATNAFGMGIDKADVRFVVHYAMCDSLESYYQEAGRAGRDSQRAYALLLVASDDSD
                     RIARRFEQEFPPLEKIKEIYERICSYLQIGIGDGGEASFLFNIHDFCARERLYSGTVTS
                     ALKLLQQNGYMTLTDAQENPARVMFCVSRDELYKLRVQRDELDHFIRTLLRLYNGVFTE
                     FRPIDEGELATWSGYTVQRVKELLKRLWQLRVIRYIPSNRSPILFMNEERLPRADLYIA
                     PETYKRRQELMRERFEQMIAYAANEQECRSAVLERYFGEENPAPCGVCDICLARKRAAK
                     AAAREAGTAPGTAHPEAAGDAPGSESALREKLLARLARSPADPHRLAAELACPPERLAE
                     AVRELLGEGAVRTFADGRIALFSGPDGPDKAK"
     CDS             12455..13063
                     /locus_tag="ctg38_28"
                     /transl_table=11
                     /translation="MTTVNNFIDKISNEQTALLPAVEFRGEIRIVEHERDIAAACKTLA
                     EQPVIGFDTETRPSFRPGVTFRVSLLQLSTPTVCYLFRLNKIPLAKPILQLLEDRRVLK
                     IGADVAGDLRSLRQIRHFRDGGFVDLQGIAPEWGIGEKSLRKLSAIVLGRRVSKAQRLS
                     NWEAATLTDKQQLYAATDAWVCTRIYEQLLRTPKKPIRK"
     CDS             13060..14259
                     /locus_tag="ctg38_29"
                     /transl_table=11
                     /translation="MIPQIYLRKGKEESLLRRHPWIFSGAIDHIKAEEESDFAEGALVE
                     VYTRQGEFMALGHYQVGSIAVRVLTFEREEIDQAWWNLRIAVAYDVRRTLDLTDNPATT
                     CYRLVHGEGDSLPGLVVDIYGPVAVIQCHSAGMYHARMQIAEALRTVYGARLTAIYDKS
                     SQTLPFKAALGAVDGYLWGTSDHASHIVLENGERFCVNWEKGQKTGFFLDQRENRQLVK
                     RYAKGRTVLNTFCYTGGFSVYALSGGAGEVCSVDSSERAVALATENMQLNFGDNAAHSE
                     VAADAVDYLKDIGDKYDLIILDPPAFAKHHKVLGNAMQGYKRLNARALSQIRPGGILFT
                     FSCSQAVTKELFRTTVFSAAAIAGRKVRILHQLTQPADHPINIYHPEGEYLKGLVLYVE
                     "
ORIGIN
        1 ttcgagacgc tcgaacatcg cgtcgacgaa ctccttcttc gaggccgaga agacgatcat
       61 cgtccggcgc cgccccagtc cgccgaaaac cagcgtcagc acctccagtc cgaacagcgt
      121 cagcgcggtg gccgctccgg ctacgatata catatgcgct cccgccgcca ggccgatgcc
      181 cgccgtggcc cagaggctcg ccgcggtggt cagcccccgc accagctgcc ggtgaatgat
      241 gatcgtgccg gccccgatga aaccgatgcc gctgaccacc tgcgccgcga tacggctggg
      301 gtcgagacgc agcccgtcgt gggtcgccag aaaatcctcg aatccgtatt gcgagacaat
      361 cataatcagc gcgctgccca gcgccaccag gaaatgagtg cggaaacccg catccttaac
      421 ccggtattcc cggtcgaggc cgatgatcgt tccgcaaagg cccgccacac acaaccgcac
      481 gataaaattc cattccatct ccataagcac tccgggcttc gccccgcaaa aatcatacat
      541 aaaattccgg catttctccg ggagaggtcc ccggccgccg catccggctc cgcaaaacac
      601 gaccgccggc gcgttccggg tccatccaaa agtacgggaa aaaccgggcc gccgcaagac
      661 ccggcaaagc ctcccgacct cccgaaaacg tcgttacgac accaaatgta agaaaaaatc
      721 ccggattgcg aagaattttc ggcgggaagg ttgcactgtg ggaaaaattt cgtacttttg
      781 caggctatgt ttaactaatt aactatttac gacaatgccg aaaatgaaaa ccaatgccgc
      841 tgcgaagaag cgttttacct tcaccggcac aggaaagatc aagcgcaaac acgcttatca
      901 cagtcacatc ctgaccaaaa agacgacgaa acagaagcgc aacctctgct attcgggaac
      961 cgtttctgcg gccgacgagg ccaaaatcaa gaacctgctc gttaagtaat taacccgcag
     1021 cattttatta atcgggacga accagcccca aagaatgcgg gagaaccgta tcgctggcag
     1081 tcctccaaaa actttacaat atgccacgtt cagtaaacgc tgtcgcgtca cgcgcacgtc
     1141 gaaagaaagt tttgaaactt gccaaaggta actttggttc aaggggaaac gtttggaccg
     1201 ttgcgaaaaa tacggtcgag aagggtctgt gctatgccta tgcacaccgc gccctcaaga
     1261 agcggacatt ccgttcgctg tggatcacgc gtatcaacgc cgccgtccgc gcccagggaa
     1321 tgacctattc acaatttatc ggcaaactca acgccaaggg aatcgtcctc aaccgcaagg
     1381 tgatggccga cctggcaatg aacgagccga aggcattcga ggcaatagtt aaagcagtta
     1441 aatagccctt cgcgagaagg gttttagcgc ggcggatacc ttggtatccg cctttttttc
     1501 tccggaattt ttccaggaag cacctccaac ctaaaataaa ccgcatgaaa catatgacct
     1561 tgctcctgac gacggcctcg agccggctgc acgcattcag cggcacggaa agcgacaata
     1621 gggacctcgg caccggcgcg ctcaaacttc acaccgacgg gcggcagttc cggctatgga
     1681 gcgacaaagc ccgcatgggt ttcatcctcc ctaaactcgg attctaaaag gacagaacac
     1741 atcgtggaaa gctggaaaaa aacattcgcc gtcatctgga gcgggcagct ggcctcgatc
     1801 ctcagcagcg aggtcgtggc ctactcgatc atcttctgga tgagccttga aacaggctcg
     1861 gccgaggtgc tggctctcgc agccatcgcc gggatgctgc cccagtcgtt gctggggccg
     1921 ctcgtcgggg tttacgtcga ccgctgggac cgcaagcgca cgatgatcct cgccgacagc
     1981 ttcatcgccc tctgcacgct ggcgctgacg gcgctcttct ggctcggcgc agcccggatg
     2041 tggcacatct acatcctgct ggcctgccgc tcggccggct cggccttcca catacccgcc
     2101 atgcaggcgt cggtcccgct gctggccccc gcatcgcagc tcacgcgcat cgccggagtc
     2161 aaccagatca tcgcctcgct gtcgagcatc gcgggtccgg ccctcggagc gctgctgatc
     2221 aatctcacct cgatcggcaa catcctgctg ctggacgtgg cgggagccgc catcgcctgc
     2281 atctcgctgc tgtgcgtccg gattcccaac ccggcgcgcg acacgacgcg caaacccgac
     2341 ctgtggcggg agttccgcga aggtttctcg gccatgcacg ccattccggg catgggatgg
     2401 tttttcacgc tggccatcgt cgtatggttc ttcatcatgc ccgtcggggt gatgttcccg
     2461 ctgatgacgc tccagcactt cggcggaggc gctttcgaaa tgagcctgat cgagatcgtc
     2521 tggggcggcg gggcgctcgt cggaggcgcc gtcatgggcg cgcgcaccta ccgggtcagc
     2581 cgcatcgtgc tggtcaacct gatgtatctc gtcgtgggac tctcgttcgc gctgtcgggg
     2641 cttctgtcgc ctgcgggatt cctctggttc gccctcttca cggcggcggc gggcatctcc
     2701 agcagcgtgt tcaacgcctc gttcgtctcc gtggtccaga cccggatcga agcgggcatg
     2761 ctgggacgcg tcatgtcgct ctaccgcagt ttcgggctgc tgccggcggc cctcggactg
     2821 ctgggcacgg gattcctggc cgagaacgtg ggactcacca cgaccttcgt cgtcgccgga
     2881 acgatcatcg tcgcggtggg cgcggcggga ttcttcatcc cctccgtcat gcggctcgac
     2941 cgcaacccct gatccgcccg cccggcactt gcaaaaaaat gaggcgcgca tggaacaaca
     3001 tccattcgcg cctcgcaagc aagtctgaat aagccctttt atcaatcctt cggataaacg
     3061 tatccgttgt agcgaatctt ctggaaaacc gtattggtcg aactgtcgta cgaccattcg
     3121 taggtcaccg acgatgcggg gtacttggtc gtatcatact ccagagggga gaggaaacgg
     3181 cactcctgcg ttccgctgat gatctgcatg ccgcggtaaa cgccattggt cagttcatag
     3241 cccatcccca ccgcctgcgt catgtcggac gaatagaggg tcggacccga agcgccgcct
     3301 tcgaccttga aatccttgcc cgagcagagc gaataggcca ggctcgaatc ctcggcacgc
     3361 agcgtatagc ggccggtcca gttggaggac gcatccacat tatcgagatg gatacggaac
     3421 gacgaagctc cgattatata ggaatcggcg ccgtcgaaat agagcgtagt ctccccgcca
     3481 tcgaaattga acgccgaccg cagaccggta ttcgtgtaag cgaacacctt gagatcctgc
     3541 atctcgacgg tccagggcgc agaataggag gattggttca gcaccttcgt cccgttggtt
     3601 ttcaccagca cggaacccgc catgaagaaa cggtcgggca gctgggcttc gtcgctgtaa
     3661 gtgatcagat agtcttcacc ctgccgttcg agtttcgtat gcgcgccgaa aagggtttcc
     3721 cagaccttga tcgaggcgtc gccctttttg accacgatct ccttcaggtc tgcggacagg
     3781 acatcctcgc cctgcttatc cgcttcggcc agcagcatcg ccaggcgcaa ggccgcattg
     3841 gccggccgca tggcgagttt atcctgatcc gtcgccagct gatagatgta cattccgggc
     3901 tgaacgggaa gcatctcctt ccaggtatcg ttttccttga tacagctcgt gaatgcgaga
     3961 gccgccagcg cgattgttgc aataagttta ttcatacggt atgtttggtt aatttattca
     4021 tataaacgca cccggcggca atatactgcg cggatgccgt aaaaaatttc cctttatccg
     4081 atttccgtcc ggtatgccgg cctgcagaaa cccggcagcg aacctttggc gcgccgcgtc
     4141 ggggtttcca gctccggttc gggcgtgcat cggagctgtg ctgccgcaaa gatagatttt
     4201 tttttcgcgt atgcgaaatc tattttgccg tttcgccgca aatttgtatc tttattccat
     4261 gatgctccga ctgacgacac ccctttttgc cggactgccg gagcgccaca cgctgatcgc
     4321 agatttcgcg atcgaacgat tatgaaaaca cacaaaccaa ccgtattcat tcttatgtca
     4381 ctgctctcca ttttcggctg cggccgcgca aaaacccccg aatatcccgc cgaccggctc
     4441 tccgcccgcg acgggaccga attcacgatc acctttttca agcacgcttc gctcgcgatc
     4501 tccgtgggcg gcaaatacat ctacgtcgat cccgtgagcg ccaacgccga ctacggcgca
     4561 ttgccgaagg ccgacgtcgt gctgatcacc cactcgcact acgaccacct cgacgtggcg
     4621 gccgtcgaga agctgctcgc cgccgacacc gaaatcctct gcgaccggac ctcggccgaa
     4681 gctttcgaaa tgaactgcta cacgatgcat ccgggcagcg tcgccacgcc gcgcgactat
     4741 gtgaaggtcg aggccgtcgc ggcctataac accacgccgg gccatctgca attccacccc
     4801 cgggagcgcg aggactgcgg ctatgtgctg accatcggcg gcacgcgcat ctacatcgcg
     4861 ggcgacacgg aacccacccc cgaactgcag gcgctccgaa agatcgacat cgcctttctg
     4921 cccgtgaacc agccctacac gatgaccgtc gaccaggccg tcgaagcggt gaaagcgctg
     4981 aaaccggcga tcttctaccc ctaccactac ggcgaggtgg acgaaaagac cgacatcgac
     5041 cgtctggtcc gcgagttgga gggcgtgacg gaggtccgca tccggccgat ggaatagcgg
     5101 gtacgccact gcaaaacaaa gagcgtcccg gcgggacgct cttttcacag cggtcctccc
     5161 gccctacctt ctgcgggaga ggacgcgctc tacgatgaac gagacgatca gtcccaggcc
     5221 tccgaaaacg agcaccgaac cgccataaac ggcgctgcgc gtgtcatagg actggatttc
     5281 ggttatccgg gtcagcataa agccgaaaag caacccggcg cccagcccca gcagcaagca
     5341 gccggctttc agcgccccgg ccgggatacc cggagcagtt tcggacgcag tccgtatcgt
     5401 ggcgcccgtc cgcagcccca tcggtaccag tttcaggtaa tcaatcagcg aaccgggttc
     5461 gagtttcccg ataatctcgc gccgctcgcg gcgacagata agcagttcga agaacttgta
     5521 aattcccagc gtgacgattc ccgtcaccag cgggaccatg ataaaattca taatctgtaa
     5581 aattaaaagg tttccgattc tttttttgcg atctctgccc tgttagacgc cgaatgtgca
     5641 aaaaggttac agacgacgga aaaacacggc tcacgtgtaa ccttttccgc cgcggcgcgt
     5701 ctaacggaat aaccatgcaa acggaagaac aggaactgat ccgacgaatc gcgggcggag
     5761 agacccgtct ctgcgcccgc ctggtcgatc gctacggaag agcggtttac acgctggccg
     5821 cacggatcgc cggatgcacg gaggacgccg aagagctgac gcaggacatt tttctgaagg
     5881 ccttctccag tctggaccgg ttcggcgggc ggagcagttt ctcgacgtgg ctctaccgca
     5941 tcgcctacaa cacggccgtg tcgcacgcgc ggcgcacgcg tccgaagcat tacggcatcg
     6001 acgaacggcg gctggcggcc ctgcccgaca gcgaggccga ccggctggaa gagtgggccg
     6061 aaaagcagga gcgcctcgac gcgctgaacc gcgccgtcga acggctcgat cccgaggaac
     6121 gggcgctggt aacgctgttt tactacgagg accgctccgt cggcgagtgc gccgcgatca
     6181 cggaactctc ggaaggcaac gtcaaggtgc agctccaccg aatccggaaa aaactatatg
     6241 tactggtaaa cgacgagatg aatggaacag agtgatgcga tacgccgcgc agtccggcaa
     6301 gttccgcccc cggaactgcc cgcaggcttc accccgcggc tgatggaacg gatgcggcgt
     6361 gagaccctgc ggcgcgaacg acgcgaaacg tggctgctga cggccggggg cgccggctgc
     6421 ttcgcggcgc tgatcgccgc ctgcgtgacg acgctgtggc cggactttag gctgcgaatc
     6481 accgacttcg cccttccccg ccccgaactg ccgcacttca cgctgccgca cttcgcgctg
     6541 tcggaagagg acaaatggct ggttgcaatg tgtgtctgca tcgcgctggt ctttctcgca
     6601 ctgttgctcg ccgacctcgt gatccgccgc cgcatcgcct cctcccggaa ctgaaaaacg
     6661 ggggaacctc ccgaagaggc tcccccgttt ccgataacaa acccgccgaa gctatttctt
     6721 cgcaggggct ttcttgggtt cggccttcac cttgatcgtg gcgaacccct tgacgatgtt
     6781 ctcgtcgttg ttcttcgaag cgtcgtaaat cacggtgacc tccttcttcg gcaggtccac
     6841 cttcacgtcc ttgatgccct tgccgagcga cggaacgttg ttcataatct tcttcacgca
     6901 gtgttcgcag tcgatgtccg taacgaacac cgtcgtcacc tctttcttct gcgccggttt
     6961 gccggccgca gcgcacatgc cgaggcccat caccagagcc aggcaaatca tcagaatctt
     7021 tttcatcttg ctgttatttt aaggtttcga aaatttcatt atcctgtttc cgggcctccc
     7081 ctttcaaagg gaggttcgga gggattgtct gcacggttcc ataccggtct tcaaaacagt
     7141 cctaatagag attaaaccgt aaaccgacat agaacttgcg gcccatgagc ggtccccaga
     7201 cgttcatcga gttgaacttg tagtcgtagg ggtcctgcgc attgagaatc gggtccttct
     7261 ggcggtagtc ggcgatattc tcgcacccgg cgtaaatgtc gaacttgccc accttgcggc
     7321 tcacctgcgc gaagaacatc ggataacggg gcgaatagta gctgtcgtcg aggtcgcccg
     7381 tctgcgtcgg gatgcgtgcc ggaccgttga gctgcgccgt ggcgtcgaac acccagcggc
     7441 ggaacttcgt ggcatactga atgttgagca gcgtcttgta ctggctcacc agcggacgct
     7501 ccacgcgggc cgtaccgccg tcggcgcgcc tgatcgtcat ttcgctgtcc gtgtagcgga
     7561 acgtggcgaa gatgtcgagc cgctcgaccg gcgaccacga gaagtcgatc tggtaggtgt
     7621 cggtgtacga acgtccgtcg gtgttgtaga aaacgatccg gtcggcatac atctcctgat
     7681 cggccacgac cgagttgtag aactgcgtgc ggaaatagtc gaagctcagc gtcgcatcgc
     7741 cggggttcac cagtccgaaa gtctgcgtaa ggcttccgcc gacggtcagg gccttctcca
     7801 tacggtcgaa tttccggaaa tcgaacttcc ccgattcatt gtcgaggaac gtgatcgccc
     7861 ggcccgtggc caggacgccg atattgtcgg tgatgacgtt cgtcgaacgg taacccagac
     7921 cgcccgaggc gcggagcgtc gtcgaggggg tgatgttcca cttcagatgg ccgcggggcg
     7981 tgaggaaaaa gcggtcgtaa tagtgattgt agtcgccgcg aagtccggcc acgatcgaga
     8041 acttgtcctt gatggcgtag gtatactcgg cataggctcc ggcctcgcgc tcgttgcggt
     8101 cgaaatcgta gttgcggacg ctgttggcgg cgatccacgg cgtgggattg aggagcttct
     8161 cgcggtagta gtccaaatgc ccctgcacgc cgacgatcag cgacgaacgg taggtgaaat
     8221 agtggttgta catcagattc agcgccagcg aattctggtt gcccgtgtag tcgttcagcc
     8281 cgaaataggc gtcttcgctg aagtggtcga agtcggcgac gaacgccagg ttcgagcgca
     8341 tctcgtcctg ttcgtcgggg tcgtagaccg ccggaccgac cggcataccg actttaaaat
     8401 agccgttggc gttgcggttg cggatgtgcg aaccgtagag cggcatcttc ttgtcgccgg
     8461 cccgccagtc ccagtccttc tccatcgcct cgcgcatagt ccgggtgttc ttgtagtcga
     8521 gcatgccgcc cagacgattc tcctgcacga acttccagcc ccagcgcacc tgcgtgccgt
     8581 tgtcggcggc atagagccac ttgttggcca cgttgatctg gtcggatttc ggcaggtcgc
     8641 ggaagccgtc gtggttgtgg tccatcttcc gggcgtcggt gtccatcgaa ccgtgaagca
     8701 gaatgacgct cgacagtttc ttgtccttcg tcacgggaaa ggccgtcgaa atattggcct
     8761 cggggcgcag ttcgtcgtcg aggtagaggt tcacgaacag ccgctcgtcg tccgtcggct
     8821 tgcggtgttc gaggttgatc tgccccgtga tggcctcgtg gcccgccgtg accgaagcca
     8881 cgcccttcga cacctggatc gagttgagcc acatgccggg cgtgtaactc aatccgtagg
     8941 gagcgctcag gccgcgcatg atcgggcggt tctcgtcgag aatctgcgta taggttccgg
     9001 ccagccccag catcttgatc tgccgggcgc cggaaatggc gtcactgtaa ccgacggtca
     9061 ccgaggccga attctcgaac gactcggcca ggttgcagca ggccatcttg cagagacccg
     9121 caaaggagat catctcgccc ttgacgatgc cgtcgcgctt gacgaagttg ccgcttaaat
     9181 tgccctcgac gacgacgcct tccagcgcca cgccctccga acggagcgcg aacgcgacct
     9241 tgtcgacgcc atttttcacg tccagcgtgt cgttgacgaa gcccagatac gaggccacga
     9301 gcttgtcgta gccctttacg cagtgaagga ggaacgcacc ctgggcgtcg gtgctggctc
     9361 cgatggtcgt accggcccag tagaccgagg cgccgacaag cggttgattc tcggcatcgc
     9421 ggaccacgcc ccgcaaatcc tgcgcacgga gcgaaccgca cgcggcgagg gcgaaaaatg
     9481 aaaatacagt gattttgaaa aatttcatgg aaattccgtt attggttaaa actgattacg
     9541 gaccggcgta cacgacaccg gtcccgaagg agtcttaaac caatacggga ggagcgcgga
     9601 agccgacgga gcatgccgag gcttcccgga cgaaaggcgt tcgcctctcg gcgaccttct
     9661 cgcgcagaaa gggaacatgc gcgggacacg ggcactctgc ggcgagcgca ggcggcaggt
     9721 cgaggacgat gcagcgggta taccgctcgt tgttgtcgaa agacgaggaa acgtagagtt
     9781 cgatttcggt cgaatggtgg ttgccgcagc agggtgcgcg catctcaccg ccggccgcgg
     9841 ccggaaggtc cgccacatgg aggcaatggc agcagcacgc atgctccgtg cgggccttca
     9901 ttgccacgca cttgcacgtc agcgacgcca aagccgtccc cgccgtcgca aaaagataga
     9961 cggcgagcag cagcagcgat atggaccttt tcaatttcat ctactcttcc acgattccgc
    10021 attcggcgag gctcgcgatc caccgcccgg catccttccg ggccgtgtcg gcgtcgacct
    10081 cgtaacgctc ggtgagcagc agcgcggcat ccgcagccgt aaactcgcgt ccccgcagct
    10141 tctcccacag atacatcgac gaaggattga gcgacacgat gcgtgtcata tcggcggcgc
    10201 ctccgcgccc cggcatcacg atcacgtgct cgccggccat ctcccggact ttgaattctt
    10261 cgcgtatctt catctgtcga acgttctgat cttcgcaaaa gtataaaaaa atctccaaac
    10321 cgcctaattt ttttacaaaa cggcttgcaa acggcttttg ccccgtccct tcttttttat
    10381 acctttgtgt tatgaaaccc gcaccggaca ggatatacga cacgctgaaa cgctactggg
    10441 gcttcacgga gttccgtccc gtgcagctgg agatcatccg ctccgtcctg gagggccgcg
    10501 acacgctggc gctgatgccc accggcggcg ggaaatcgct cacgtatcag gtcccgaccc
    10561 tcgcccgcga ggggctgtgc atcgtcgtca cgccgctcat cgccctgatg aaggaccagg
    10621 tcgaccggct ccgggctcgg gccgtcccgg ccgttgcgat ccattcgggc ctttcgccgc
    10681 ggcagatcga catcgcgctg gacaactgcg cctacggcga cgtgaaattc ctttacgtgg
    10741 cccccgagcg gctggcgacc gaggcgttcc gcctgcgcgt cgtgcgcatg aacgtacagc
    10801 tgatcgccgt cgacgaggcc cactgcatct cgcagtgggg ctacgacttc cggccctcgt
    10861 acctgcgcat cgccgagctg cgcgaaaaac tccccggcgt ccccgtgctg gcgctcaccg
    10921 cctcggccac gaaaacagtg gccgacgaca tcatgcgcca cctgaaattc cccgaaccgc
    10981 acattctgcg cagcagtttc gcgcgcccca acctctcgta cagcgtccgc cgcaccgacg
    11041 acaagaacgg acagctgctg cggctggtcc gcaacgtccc cggcacgggc atcgtctacg
    11101 tccgcacgcg ggagggcacc gagcaaatcg ccgacctcct gcgtcaggag ggcacgacgg
    11161 ccgccgccta ccacggcgga ctgggacacg ccgagcggtc gctgcggcag gaggagtggc
    11221 tctcgggcaa gacgcgcgtg atggtggcca ccaacgcctt cggcatgggc atcgacaaag
    11281 cggacgtgcg gttcgtggtc cactatgcga tgtgcgactc gctcgaaagc tactaccagg
    11341 aggccggccg cgcgggccgc gactcacagc gtgcctatgc cctgctgctc gtggcctcgg
    11401 acgacagcga ccgcatcgca cggcgtttcg agcaggagtt ccctccgctg gagaagatca
    11461 aggagatcta cgaacggatc tgttcctacc tgcaaatcgg catcggcgac ggcggcgaag
    11521 cgtcgttcct gttcaacata cacgacttct gcgcccgcga gcgcctctat tcgggaaccg
    11581 tcacgagcgc cctgaaactg ctccagcaga acggctacat gaccctcacc gacgcacagg
    11641 agaaccccgc gcgggtgatg ttctgcgtca gccgcgacga gctgtacaaa ctccgcgtgc
    11701 agcgcgacga actcgaccac ttcatccgca ccctgctgcg gctctacaac ggcgtcttca
    11761 ccgagttccg ccccatcgac gagggcgaac tggccacctg gagcggctac accgtccagc
    11821 gggtcaagga gctgctcaaa cggctctggc agctgcgcgt gatccgctac atcccctcga
    11881 accgctcgcc catcctcttt atgaacgagg aacgccttcc gcgcgccgac ctctacatag
    11941 cccccgagac ctacaagcgg cggcaggagc tgatgcgcga acgcttcgaa cagatgatcg
    12001 cctacgccgc caacgagcag gagtgccgca gcgccgtgct ggagcggtat ttcggcgagg
    12061 aaaaccccgc gccgtgcggg gtctgcgaca tctgcctggc ccgcaaacgg gccgcgaaag
    12121 ccgccgcccg ggaggccgga accgctcccg gaaccgctca ccccgaagcg gcaggcgatg
    12181 cgcccggctc cgaaagcgcc ctgcgcgaaa aactcctggc gcgcctcgcc cggtccccgg
    12241 ccgacccgca ccggctcgcc gccgaactgg cctgcccgcc cgaacggctg gccgaagcgg
    12301 tgcgcgaact gctcggggaa ggggcggtcc ggaccttcgc agacggacgc atcgcgcttt
    12361 tcagcggtcc cgacggcccg gacaaggcaa aatagcgcgc cgaagagccg cttttctgaa
    12421 aataaatgca taaatttgtg ggaattttca ccgcatgacc acagttaaca acttcattga
    12481 taaaatcagc aacgagcaga ccgccctgct cccggccgta gagttccggg gggagatccg
    12541 catcgtcgaa cacgaacgcg acatcgccgc ggcctgcaaa acgctcgccg agcagcccgt
    12601 catcggcttc gacaccgaga cgcgcccctc gttccgcccg ggcgtcacgt tccgcgtatc
    12661 gctgctgcaa ctctccacgc cgacagtctg ctacctgttc cggctcaaca agattccgct
    12721 ggccaagccc atcctgcaac tgctcgaaga caggcgggtt ctcaaaatcg gcgccgacgt
    12781 ggcgggcgac ctgcgctcgc tgcgccagat ccgccacttc cgcgacgggg gcttcgtcga
    12841 cttgcagggc atcgcccccg agtggggcat cggggagaag agcctgcgca agctctcggc
    12901 catcgtgctg ggccggcgcg tctcgaaagc ccagcggctg agcaactggg aagccgcgac
    12961 cctcacggac aaacagcagc tctacgccgc gaccgacgca tgggtctgca cccgcattta
    13021 cgaacagctg ctccgcacac cgaaaaaacc gatccgcaaa tgataccgca aatttacctg
    13081 cgcaaaggca aggaggaatc gcttctgcgc cgccacccgt ggattttctc gggcgccatt
    13141 gatcacatca aagccgagga ggagtccgat ttcgccgaag gggcgctcgt cgaggtctac
    13201 acccggcagg gcgaattcat ggccctgggc cactaccagg tggggtcgat cgccgtgcgc
    13261 gtgctcacgt tcgagcgcga ggagatcgac caggcgtggt ggaacctccg gatcgccgtc
    13321 gcctacgacg tgcgccgcac gctcgacctc acggacaacc ccgcgacgac ctgttatcgc
    13381 ctggtccacg gcgagggcga ctcgctgccg ggcctcgtcg tcgacatcta cggcccggtc
    13441 gccgtcatcc agtgccactc ggcgggcatg taccacgcgc ggatgcagat cgccgaggcg
    13501 ctgcgcacgg tctacggcgc acgcctcacg gccatctacg acaaatcgtc gcagacgctc
    13561 cccttcaagg ccgccctcgg agccgtcgac ggctacctgt ggggaacctc ggaccatgcg
    13621 tcgcacatcg ttctggaaaa cggcgagcgg ttctgcgtca actgggaaaa ggggcagaaa
    13681 acgggcttct tcctcgacca gcgcgaaaac cgccagctgg tcaaacgcta cgccaagggc
    13741 cgcaccgtgc tcaacacctt ctgctacacg ggcgggttct cggtctacgc cctctcgggc
    13801 ggcgccgggg aagtctgctc ggtggactct tccgaacgcg ccgtggcgct ggccacggag
    13861 aacatgcagc tcaacttcgg cgacaatgcg gcccactcgg aggtagccgc cgacgcggtg
    13921 gactacctga aggacatcgg cgacaaatac gacctgatca tcctcgaccc gccggccttc
    13981 gccaagcacc acaaggtgct gggcaacgcc atgcagggct acaagcggct caacgcccgg
    14041 gccttgtcgc agatccgccc cgggggcatc ctcttcacgt tctcctgctc gcaggccgtc
    14101 acgaaagagc tgttccgcac gacggtcttt tccgccgccg ccatcgcagg ccgcaaggtg
    14161 cgcatcctgc accagctgac ccagcccgcc gaccacccaa tcaacatcta ccatcccgaa
    14221 ggcgaatacc tcaagggact ggtgctttat gtagaataag ccataaaaaa agacttatta
    14281 gtcaaaacgg gtgctgaaac gcctcaaaaa caggaaaacg ccacgctata ggtcaaaacg
    14341 ggtgccgata gcgtggcatt ctatttgatt ttcagtatat tttggcattt g
//
