LOCUS       c00002_gnlPro..        15106 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GPJBPKJD_2.
ACCESSION   c00002_gnlPro..
VERSION     c00002_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 14:57:04
            Original ID  :: gnl|Prokka|GPJBPKJD_2
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15106
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15106
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[3038:5106]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /neighbourhood="10000"
                     /product="gallic_acid_met"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      3039..5106
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /neighbourhood="10000"
                     /product="gallic_acid_met"
                     /protocluster_number="1"
     cand_cluster    1..15106
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [Flavoprotein,
                     Semialdhyde_dh]) and gallic_acid)"
                     /kind="single"
                     /product="gallic_acid_met"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15106
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="gallic_acid_met"
                     /region_number="1"
                     /rules="(minimum(1, [Flavoprotein, Semialdhyde_dh]) and
                     gallic_acid)"
                     /tool="gutsmash"
     CDS             2..133
                     /locus_tag="ctg2_1"
                     /transl_table=11
                     /translation="GTLELRAKNKPKVTSELNIQFGYALPILLVFGLGIWWFVKSHG"
     CDS             153..572
                     /locus_tag="ctg2_2"
                     /transl_table=11
                     /translation="MQSVQEFTVTKEHYTMQAALFVIAKDVLAVITGGDHPHIGDVTAV
                     AKGEEPQTVRYPSHDGRFHKDDFLSERLVKKVAPLVPGSLTVLAGVHVDHITKTQLIQA
                     GPMIDELAQQVAAWLLAHPIQFSDAQYYGDDEQPS"
     CDS             complement(617..1513)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     54.1; E-value: 3.8e-17)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg2_3"
                     /sec_met_domain="LysR_substrate (E-value: 1.5e-29,
                     bitscore: 97.8, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 3.1e-16, bitscore: 54.1,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNINDFQGFIYIYQLRSITKAATQMHLSKPEMSKRLRSLEAELNL
                     QLVDRTNRRALKITPAGRTFYHHALSMMEQYQAMMRDLATIRHPLTNQIKIGTIPVVGQ
                     YKITAGITRFNQQHPQLQATLLENEGDVIIEQLHQGEIDAAILRDTQSAQFDEATYYRK
                     TLVTDQLMVIVPKNSPLANRRALAIPDLKHVQIASLPVGSGVYEPIAQLFAHHNLTPHI
                     FFQSTHIETLISLLGYDNTVTLLFKKSITPFLNDQVVMIPVQPSFNSCLQFVFKNNTGS
                     YQLHHLLSSVQDYLAKV"
     CDS             complement(1639..3039)
                     /locus_tag="ctg2_4"
                     /transl_table=11
                     /translation="MSTEFAKKELLNKRVLGFFGGIIVFLLIYLAPISGLGYTGKMDLA
                     LSLMTVVWWATQVAQPAYVGGFFLMMLIITKTATPAQVFSKPWTGSTMWLVMGAYLIAG
                     AVNESGVGQRIAYAFIIRFVRSWNGLIVGIFVLTFILALLIPHPWPRAFMILAVVLAVG
                     RAADMDKDDLGKLGLAIFAASCPLSGVFLTGDTSLNPLAVADSGISVSFVRYFEVMSVP
                     MIVAALITMFLIMFLFKPNKPIKIDVAQLKVEQQKLGQMSGKEKRTIFWIVVAIILWLT
                     SSITGIDVGWLTLTVAVLMSMPVIGGILTPASWSGVQINVLVFLTSAMAIGNVGAVTGM
                     NKWLATTVIPGNLPHNIYLLSLEITLFAMIIHMFMGSVIAVMGITIPAFVTATAHMGIS
                     PLAISLLVFSVTNLHYILPFHNLAVLVGMDGGGYTAKQVSKLGIALTPFILLIAIVLMF
                     WFHICGLA"
     CDS             complement(3039..3602)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     gallic_acid_met: Flavoprotein"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_5"
                     /sec_met_domain="Flavoprotein (E-value: 2.1e-26, bitscore:
                     87.5, seeds: 91, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVIGVSGASGTIYAVDLLKKLHQVPDVETHLIMSAWAKKNLE
                     LEADLSLADLTALADVVHNNHDLGATVASGSFLTSGMVIVPASMKTISGIANAYDDSLI
                     TRAADVTIKEKRRLIIVPRETPLSEIHLENLLKLARVGAQIIPPIPAFYNHPQTIQDLV
                     DHQSMKIMDSFGIEHHFGHRWEGD"
     CDS             complement(3631..5106)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     gallic_acid_met: gallic_acid"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg2_6"
                     /sec_met_domain="gallic_acid (E-value: 1.8e-223, bitscore:
                     736.7, seeds: 25, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTEQPWDLRRVLDEIKDDPAEYHETNEPVDPNAELCGVFRYIGAR
                     GTVERPTKLGPTMMFNNVKGFPDTRVLIGLMASRQRVGKMFHTDYAHLGEYLNQAVSKP
                     VAPVVVDEDKAPAHEVVIKADDPDFDLRTLVAAPTNTPEDAGPYITCGVVLGSNMDKTM
                     SDVTIHRMCIEGKDTLGVYIMPGGRHIGAFAEEYEKANQPMPITINIGLDPAITIGCTF
                     EPPTTPLGYNELGVAGAIRNQPVDLVKAVTVDEIVIARSEYTLEGYIMPNERIQEDINT
                     HTGKAMPEFPGYDGDANPSLQVIKITAVTHRKDNPIMQSVIGPSEEHVSMAGLPTEASI
                     LSLTDKTIPGKVLNVYNPPAGGGKLMTIMQIHKDNPADEGIQRQATLLAFSAFKELKTV
                     FLVDEDVDIFDMNDVVWTINTRFQADQDIMVLPGMRNHPLDPSERPQYDPKSIRFRGMS
                     SKLVIDGTVPFDMKDQFERAKFKDVPDWEKYLK"
     CDS             5431..5595
                     /locus_tag="ctg2_7"
                     /transl_table=11
                     /translation="MKKRKKYSLKEHYNRLMEKLFLEGEEEPDYLVENFFSMPVLFFGL
                     RIFCLFFYP"
     CDS             5643..5801
                     /locus_tag="ctg2_8"
                     /transl_table=11
                     /translation="MKDHLLKWCAGSLQIDFRQEEGRKLTLGFKIELGCIFAVVFGGLV
                     YWWVKVH"
     CDS             complement(5950..6063)
                     /locus_tag="ctg2_9"
                     /transl_table=11
                     /translation="MEKLDYSSALRRLKSPNIKTRKRALKTIKQLKAQKNK"
     CDS             complement(6051..6368)
                     /locus_tag="ctg2_10"
                     /transl_table=11
                     /translation="MSASYTDQEVIALIGRVLNHYHLSGEHFLFNRTATGLEVLTTPND
                     ESWLLVSLLGWLQADFDLTFLDGAGHPVDFCDHRALMFTIRSVDEDAINSLLPKDDQWK
                     N"
     CDS             complement(6368..6532)
                     /locus_tag="ctg2_11"
                     /transl_table=11
                     /translation="MATPAHRTSKTKKRMRRGHIKLNVPNVRLAPATGEYTLPHHVSPS
                     GQYKGRSVK"
     CDS             complement(6559..6687)
                     /locus_tag="ctg2_12"
                     /transl_table=11
                     /translation="MRRPIVLFCSQTGERYLTTKNKANTPDRLRLLKYSTKLRRRV"
     CDS             6874..7419
                     /locus_tag="ctg2_13"
                     /transl_table=11
                     /translation="VNRQQEAELQQRIKKGIQFPEELFKMAEQTGRTIPDYQRLKEHRQ
                     KGWPLLKADIASLEAIANGRKIEEPRRPSSTVRIERPAKKKRSTATKAEANAKANAKQA
                     ARDRLAKMLRRYNGLVASGESLGVMENERDRRWMHIAETVLNDAEATTRALSSQANKIE
                     TKIERIEERLLRRQERYY"
     CDS             7556..8137
                     /locus_tag="ctg2_14"
                     /transl_table=11
                     /translation="MNIIRQKNTENELHNIVHQFTSLIGLSKLTKLVNYRRNSEISLMK
                     VIEWLLTTKFLGRSLYRAHETPNFTSRTVRNNLNDGRINWQRLICQVGSHLIKYLRPFI
                     DRRRRLALIIDDTLFSREYATQTELLARVFDHDKQLYIKGYRALTLGLSDANTFLPINF
                     ALMSSKKPQNVLGKSAKTTDQRTIAGRRRR"
     CDS             8296..8922
                     /locus_tag="ctg2_15"
                     /transl_table=11
                     /translation="MLKRSSKIYYQYRGRQYSVKALYKRLQASKYQPKQAYQYSCFVEA
                     HVGNQKFKLRLVFVANRARQDDYLVLATTQLGLQPQAIIQLYARRWQIENYFKVAKQYL
                     RLDKSQVQNYDGLCGHLAIVMMTYDLLAWQERQNQDDRTIGDLFFIMNEAMPDIELSQA
                     LVWLLNSLKTIINHEVYARRAQIIQMMNQFFTFLPKRLVSLLTAS"
     CDS             complement(9013..9246)
                     /locus_tag="ctg2_16"
                     /transl_table=11
                     /translation="MIVPLTFSTIVIILLIPVFWILRKIFWPTILIGLMLILLGAGSAH
                     WFEPVINTIAIINLILAIVYGILKIINSFVNK"
     CDS             9490..10284
                     /locus_tag="ctg2_17"
                     /transl_table=11
                     /translation="MTNLTNLSPAEFRRLVRTGDFTSPTSGYCPGYTQANLVIVPQRYA
                     YDFLLLAQRNPRPCPVLEVSDAGSRGLTNFATDVDLANDFPKYRVYRGGELNEEVTSVE
                     RLWQDDFVSFLIGCSFSFEAELLAAGIEVRHITEGVNVSMYNTNLPLQGTGALHGNMVV
                     SMRPIPASQVAKAVEVTAAMPRVHGAPIHVGDPASLGIKDLSHPDYGDPVTIKDGELPV
                     FWPCGVTPQNAIMQSKLPLVITHAPGHMLITDVLNADLKGNG"
     CDS             10620..11585
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OTCace"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OTCace_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_18"
                     /sec_met_domain="OTCace (E-value: 1e-23, bitscore: 79.1,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 7.2e-33, bitscore:
                     108.6, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTQLVEQLVSLPHFVSVEDLTTDQVNALIARAEEFKNGAPAPKL
                     SQPVYVTNMFFENSTRTHTSFAMAEKKLGLTEIPFDTSHSSIKKGETLYDTCLTLDALG
                     VDLTVIRASENDYYLPLINPGAGHYLGLGIVNGGDGSGQHPSQCMLDIMTIHEHFGHFK
                     GLKVAIVGDITHSRVARSNMEILNKLGAEVYFSGPEYWYDHAFDKYGKFLPIDELVEEV
                     DVMMLLRVQHERHAGDAHEGDFSAADYHKQYGINEERYALLKPDTIIMHPGPINRGVEL
                     ADSLVEAPKSAFVAQMKNGVFMRMAMLEAVLRGRKLGGLE"
     CDS             11585..12874
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Amidohydro_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_19"
                     /sec_met_domain="Amidohydro_1 (E-value: 4.7e-49, bitscore:
                     162.4, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTLIKNGTVYNDGRLVKEDVLVEDGIIRAIGKDLHEYLDDDYDE
                     LDAGNLLVSPGLVDVHVHYREPGQTEKETIRTGSAAAAHGGFTTVGAMPNVDPVPDTPA
                     KVAQMVAKNKQDGLVHIAQYSAITTDRTSDEVVDMAGVKRAGAFAVSNDGNGVQAAGTM
                     YRAMQAAKAVGLPLAAHVEDESLLFGGVMTGGDRSRYLGLPGAPEVVESAQVARDLALA
                     KATGVHYHVCHVSTKDSLEMIHFAKQNGVRVTCEATPHHLLLSDQCIDGHDSNYKMNPP
                     LRHEADRRALVAALNDGTVDMIATDHAPHTEEDKGRDFCCAANGITGSETAFALLYTKL
                     VKTGLLKLERLLDLMATNPAEAFNLTEAGHLEVGKPADIAVFDLNHPYVIDQRDYLSKG
                     INSPFTGMTVYGQTVMTMVDGQVVYQRKEN"
     CDS             12876..13958
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GATase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg2_20"
                     /sec_met_domain="GATase (E-value: 1.7e-46, bitscore: 153.3,
                     seeds: 97, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VQRYLVLEDGTTYRGTAFGADQAKTGEVVFTTGMTGYQEAITDQS
                     FANQILVFTNPLIGNYGVNLDDDESLLPEIKGVVCRKLARVATNWRMQDDLANFLTQRG
                     IPGLEGIDTRALVKKLRQHGTLRGRLVDDLTDLDQVVAALKQATPMKNIIPLVSTKSPY
                     PNPGTKRNIVVVDFGIKHSILRELAKRDCNVIVLPHTATATQVLNLHADGVLLSNGPGD
                     PLEMTAAAEMVKEVEQHLPVFGICMGHQILALANGAKTVKMKFGHRGFNHPVKNVATGE
                     VNFTSQNHGYAVDTTSIDPDRLLITHVEINDGTVEGLRHKHYPAFSVQFHPDAAPGPHD
                     AEQLFDDFINLVDQRKKGRN"
ORIGIN
        1 gggcacgtta gagttgcgcg ctaagaacaa acccaaggtg acctccgagc ttaacatcca
       61 gtttggctac gcactgccga tactgctggt gttcgggctc ggaatctggt ggtttgttaa
      121 gtcacacggt taagggagaa aggaaagttc acatgcaatc tgttcaagag ttcaccgtta
      181 ctaaggagca ttacaccatg caagcggccc tgtttgtgat cgcaaaggac gtcctagctg
      241 tcatcacggg gggcgaccat ccccacattg gcgacgtgac ggcggtggcc aagggtgaag
      301 agccgcaaac ggttcgctac cccagccacg atggtcgctt tcacaaggat gatttcttgt
      361 cagagcgact ggttaaaaag gtggcgccct tagtaccggg ctctttaacg gtactggcgg
      421 gggttcacgt cgaccacatc actaagaccc agctaatcca ggccggtccg atgattgatg
      481 agttagccca gcaggtagcc gcgtggctgt tggcgcaccc cattcagttt tcggacgccc
      541 agtactacgg tgacgatgaa caaccgtctt aacgaaaaac ccctgaccaa gcgccgtgct
      601 ttggttaggg gttttactat actttagcaa ggtaatcttg cacggaggac aggaggtggt
      661 ggagttggta ggagccagtg ttgttcttaa agacaaattg gaggcaactg ttgaaacttg
      721 gttgaacggg gatcatcacc acctggtcgt ttaaaaaggg cgtaatggac ttcttgaaca
      781 gcagggtgac ggtattgtca taccccagca agctaattaa ggtttcaatg tgagtgcttt
      841 gaaagaagat gtggggcgtc aggttgtggt gggcaaagag ctgggcaatc ggctcgtaaa
      901 cccctgaccc cactggcaaa gaggcgatct ggacatgctt gaggtcggga atggcgagcg
      961 cccttctgtt agcgaggggt gagtttttag ggacgatcac cattaattgg tcggtcacca
     1021 gggttttgcg gtagtaggtc gcttcgtcga attgagcgga ttgggtatcg cgcaggatgg
     1081 cggcgtcaat ttctccctga tggagttgtt caatgattac gtcgccctca ttttcgagga
     1141 gggtcgcttg gagttggggg tgttgctggt taaaccgggt gatcccagcg gtaattttgt
     1201 attggccgac cactgggatg gtgccaatct taatttggtt agtcagcggg tggcggatcg
     1261 tcgctaaatc gcgcatcatc gcctggtact gttccatcat tgacagggcg tggtggtaaa
     1321 aggtccgccc ggcaggggta attttcaaag cccggcggtt agtgcggtcc acgagttgca
     1381 agttgagctc tgcttcgagg ctgcggagcc gtttcgacat ctcgggtttg gagaggtgca
     1441 tttgggtggc ggccttggta atgctacgga gttggtaaat ataaataaag ccttggaagt
     1501 cgttgatgtt catggcgggg tctccattca agcaatgtta tttacattat acgctgacct
     1561 accgcttttt aaataacggt gtagcgccct tatcaaccac caaaagggtg ccacccgttc
     1621 ggcgacaccc taactagatt atgctaggcc acagatgtgg aaccaaaaca ttaagacaat
     1681 ggcgattagg agaataaacg gcgtgagggc aatccccaac ttcgagactt gcttggcggt
     1741 atagccaccg ccgtccatcc cgactaaaac ggccagattg tggaacggca ggatgtagtg
     1801 caagttggta acagagaaga cgagcaggga aattgcgagg gggctgatcc ccatgtgagc
     1861 cgtagcggtg acaaaggccg ggatggtgat ccccatgacg gcgattacgc tccccataaa
     1921 catgtgaatg atcatggcaa agagggtaat ttcaagggac agcaggtaaa tattgtgcgg
     1981 taagttaccc ggaatgaccg tcgtcgccag ccacttgttc atcccggtga cggcccccac
     2041 gttcccgatc gccatggccg aagtcaagaa gacgaggacg ttgatttgaa cgccggacca
     2101 ggaggcgggc gtcaggatcc cgccgataac gggcatgctc attaacacgg ccacggttag
     2161 ggttagccaa ccaacgtcaa tgccggtaat cgaactggtc agccataaga tgatggccac
     2221 cacgatccag aagatggtcc gcttttcctt gcccgacatc tggccgagtt tttgttgttc
     2281 cacctttaac tgtgccacgt caattttgat cggtttgttg ggcttgaaga ggaacatgat
     2341 caagaacatg gtaattaaag cggccacgat cattggcaca ctcatcactt caaagtagcg
     2401 aacgaagctg acgctgatgc cggagtcggc cacggctaac gggtttaagg aagtatcccc
     2461 ggttaaaaag acccccgaca gcggacagga ggcggcaaag atggccagtc caagcttgcc
     2521 cagatcgtct ttatccatgt ccgccgcccg ccccacggcg aggaccacgg ccaagatcat
     2581 gaaggcccgt ggccacgggt gcgggatcaa gagggccaag ataaaggtca ggacaaagat
     2641 gccgacgatt aagccgttcc aggagcggac gaagcgaatg atgaaggcgt aggcgatgcg
     2701 ttgccccacc cccgattcat taacggcgcc ggcaattaaa taggccccca taaccaacca
     2761 catggtcgac ccggtccagg gcttggaaaa gacttgggcc ggggtggccg ttttagtgat
     2821 gattaacatc attaggaaaa agcccccgac gtaggctggt tgcgcaacct gggttgccca
     2881 ccagacgacg gtcattaaac taagggcgag gtccatttta ccggtgtaac ccagcccgct
     2941 aattggggcc aggtaaatca acaggaaaac gatgatcccg ccgaaaaagc cgaggacccg
     3001 tttatttaaa agctcttttt ttgcaaattc agtactcatt aatctccctc ccagcgatgg
     3061 ccaaagtggt gctcaatgcc aaaggaatcc atgattttca tcgattggtg gtcgaccaga
     3121 tcttgaatcg tctgcgggtg gttgtaaaag gcggggatcg gggggatgat ttgcgccccg
     3181 acccgggcca gtttcaacag gttttccagg tgaatttcac tcagtggggt ttcgcggggg
     3241 acaatgatta accgccgctt ctccttgatc gtgacatccg ccgcccgggt gatcaaactg
     3301 tcatcgtagg cgttggcgat tccagaaatg gtcttcatgc tggccggcac aatgaccatc
     3361 ccagacgtca aaaatgaacc gctggcgacc gttgctccca ggtcgtgatt gttatggacc
     3421 acatcggcca gcgccgtcag gtcggccaag gagaggtcgg cttcaagttc caggttcttt
     3481 ttggcccagg cgctcataat caggtgggtc tcaacgtctg gaacttggtg cagttttttc
     3541 agtaggtcaa cggcgtaaat cgttcccgag gcgccggaaa ccccaatcac aatgcgtttc
     3601 attttgttcg tcctcgtttc taactggttt ttacttcagg tatttctccc agtccggcac
     3661 gtccttaaac ttagcccgtt caaattggtc cttcatgtca aacggcacgg taccgtcgat
     3721 gacgagcttg gagctcatcc cccggaagcg gattgacttc gggtcgtatt gtggtcgttc
     3781 ggatgggtcg agtgggtggt tacgcattcc tggcaggacc atgatgtctt ggtcggcctg
     3841 gaagcgggtg ttgatcgtcc aaaccacgtc gttcatgtcg aagatgtcaa cgtcttcatc
     3901 caccaagaag accgtcttca attccttgaa ggccgagaaa gccagcaggg tggcttggcg
     3961 ttggatccct tcgtcggccg ggttatcctt gtggatttgc atgatcgtca tcaacttccc
     4021 cccaccagca ggcgggttgt agacgttgag gaccttgccc gggatcgtct tgtcggttag
     4081 ggacaggatc gaagcctcgg ttggcaggcc ggccattgaa acgtgttctt cggatggtcc
     4141 gatgacactt tgcatgattg ggttgtcctt acggtgggtc acggcggtga tcttgattac
     4201 ttgtaggctg gggttagcat cgccatcgta accagggaat tctggcatcg ccttacccgt
     4261 gtgggtgttg atgtcttctt gaatccgttc gtttggcatg atgtagcctt ccagggtgta
     4321 ttcggaacgg gcgatcacta tttcgtcaac tgtgaccgcc ttcaccaggt caactggttg
     4381 gttacggatg gccccggcca cgccgagttc gttgtaaccc agtggcgtcg tcggcggttc
     4441 gaaggtgcac ccaatcgtga tggccgggtc caagccaatg ttaatcgtaa ttggcattgg
     4501 ctggttggcc ttttcgtatt cttcggcaaa ggccccgatg tgacgaccac ccggcatgat
     4561 gtaaacgccc agggtgtcct tgccctcaat gcacatccgg tgaatggtga cgtcactcat
     4621 cgtcttgtcc atgttagagc cgagcaccac cccgcaggtg atgtacgggc ctgcgtcttc
     4681 cggcgtgttg gttggggcag cgaccagggt ccgtaagtcg aagtccgggt cgtcagcctt
     4741 gatcacaacc tcgtgggccg gggccttgtc ttcgtcaacc acgaccgggg cgactggctt
     4801 ggaaacggcc tggttcaagt attcgcctag gtgagcgtag tcggtgtgga acattttccc
     4861 gacccgttgg cggctcgcca ttaacccgat taacacccgg gtgtcaggga agcccttgac
     4921 attattaaac atcatcgtgg gccccagttt tgttggccgt tcaacggtcc cccgggcacc
     4981 aatgtagcgg aagaccccgc agagttcggc gttggggtcg accggttcgt tcgtttcgtg
     5041 gtattcggcc ggatcgtcct tgatttcatc gagcacgcgg cgtaagtccc atggctgttc
     5101 tgtcataaca aacatctcct ttgtttagtt accattattc taaaaccgac tggaaacgct
     5161 ttttattcga gataattagc tttatcattc caaatcggaa tattaacttc acaaaccaga
     5221 actagcgggt cttcacgagg ggcactcttt ttatgcaacg gggcgatttt ttaaaggcgc
     5281 ccttagattt tgcacgaaaa tggtcgcaaa atagttaaat aaattttgat agcgacattt
     5341 tatgtctagc tcccggagta gacttgagat aagttggagg tgaaaacttt tattaggggt
     5401 ttgtgcaccg tcgtaggtaa ggaggatgga atgaagaaaa ggaaaaagta ctcactcaaa
     5461 gaacattaca atcggctaat ggaaaagttg tttttggagg gggaagagga gccggattat
     5521 ctggtggaaa atttcttttc catgccggtc ttattttttg gcctccggat cttctgtctt
     5581 ttcttttatc cgtaagggga tactttccgg cacggtagag cagtagatgg gaggtgatga
     5641 taatgaaaga tcacttgttg aagtggtgtg ctggttcgct acaaattgat tttaggcaag
     5701 aagaggggcg taagctgacc ttgggtttca aaattgagct tggctgcatc ttcgcagtag
     5761 tttttggcgg cctggtatat tggtgggtaa aagtccatta aaaaagcccc aggtcgattg
     5821 acgtggggcg gtggcggaaa gagagggtgt ttcgccaggt taggattatt caattaatga
     5881 cggtgcaccg atctaaagct gtaaatgatg aaaagttatt tgaaaagaag gcagatcggc
     5941 gccgcaccgt tatttattct tttgggcttt cagctgtttg atggttttga gggcgcgctt
     6001 gcgggttttg atgttgggac tcttcagccg ccgcagtgcg cttgagtaat ctaatttttc
     6061 cattggtcat cctttggcag tagtgaatta attgcgtctt cgtccaccga acggatggta
     6121 aacatcaggg cccggtggtc gcaaaaatcg acggggtggc ccgccccatc caagaaggtg
     6181 aggtcaaaat cggcttgcag ccacccgagt agggaaacga gcagccagct ttcatcgttg
     6241 ggggtggtaa gcacctctaa gccggttgcc gtacggttaa ataagaagtg ctcgccgctt
     6301 aggtggtagt ggtttaacac ccgcccaatc aaggcgatca cctcttggtc ggtgtagcta
     6361 gcactcatta cttcacggaa cgccccttgt attgcccact tggtgaaacg tggtggggta
     6421 gggtgtattc gcccgtagcg ggggcaagcc ggacgttggg aacgttcaac ttgatgtggc
     6481 cacggcgcat ccgtttcttg gttttggaag ttcggtgagc tggtgttgcc atttgatccc
     6541 tccttattct tcaacgaatc acacccgccg ccggagcttg gtggagtact tgagtaaccg
     6601 tagccggtcg ggggtgttgg ccttgttctt ggtggttaag tagcgctcgc cagtttgcga
     6661 gcagaataaa acgattggtc gccgcatcgg ggacctccta actaaatccg gattttgatt
     6721 taatagtaat aattactatt aagaacttag cacgtgtcgc taattttgta aacccggttt
     6781 aacaaaaaaa gaggggtgcc ggctctttaa cccgcgtccc agcagtgatt taactatggt
     6841 aaaattattt ggtaaaaaat gggggagata agtgtgaatc gtcaacaaga agccgaactg
     6901 caacaacgga tcaaaaaggg gatccaattc cccgaggaac tctttaagat ggctgaacaa
     6961 accggtcgga caattcccga ctaccagcgg ctgaaagaac accgccagaa ggggtggcca
     7021 ctgttaaaag ccgacatcgc cagcttagaa gcgatcgcta acgggcggaa aatcgaagaa
     7081 cctcgacgcc cctcttcaac ggtgcgaatt gagcggccag ccaaaaagaa gcggtcgact
     7141 gccaccaaag cggaagctaa cgccaaggcg aacgccaagc aggcggcccg tgaccggtta
     7201 gccaaaatgc tgcgccgcta caacggcctg gttgcgagcg gcgaatcgct gggcgtgatg
     7261 gaaaacgaac gcgaccgccg ctggatgcac atcgccgaaa ccgtgttaaa cgatgcggag
     7321 gcaaccaccc gggccttaag tagccaggcc aataagatcg aaaccaagat cgaacggatt
     7381 gaagaacggc tactgcgccg gcaggaacgg tactattaat aaactgaaac ttgaaagcta
     7441 ataatcacgc caaaggcgtg tggttattgg cttttttggc aaaaaaataa acgcaagctc
     7501 tcctgcgttg tatactttag tcgatcaaaa ccaagatacg aaggagactt acgtcatgaa
     7561 tattataaga caaaaaaata cagaaaacga gcttcacaat attgttcatc aatttacttc
     7621 ccttattggt ctatctaaac tcaccaagtt ggtgaattat cgccggaatt cagaaatcag
     7681 cttgatgaag gtcattgaat ggctgctcac gacaaagttc ctgggacgct cgctttatcg
     7741 agcccatgaa acgcctaact ttaccagtcg caccgtcaga aataatttga acgatggccg
     7801 gatcaattgg caacgcttga tttgtcaagt tgggagtcat ttaatcaagt atttacgacc
     7861 gtttattgac cgccggcggc ggttagcatt gatcattgac gatacactct tttcccgtga
     7921 gtacgccacc caaaccgaat tactagcgcg agtctttgac catgacaaac aattatatat
     7981 taagggatac cgggctttaa ctttgggttt gagtgacgcc aatacattct taccgatcaa
     8041 ctttgcatta atgtcttcca agaagccaca aaacgtcctt ggaaaatcag ctaaaacaac
     8101 cgatcaacga acaattgctg gccggagacg tcgctaagca cagcaaaaaa tgaacctcgt
     8161 ttcattgcaa cttgtcaagc aagccctcgc aaatggcgtt ctagctgact atgtgttatt
     8221 tgatagctgg tatagctcac caaaaatgtt ctatgaatta accaagttgg gattaaacgg
     8281 cgtaacggcg tgggcatgct taaacggtcc agcaaaattt actatcaata tcgcggacgg
     8341 caatattcag ttaaagcatt atacaagcga ctgcaggcct caaaatatca acccaagcaa
     8401 gcttatcaat acagctgctt tgtcgaagcg cacgtcggga accaaaaatt caagcttcgc
     8461 ttggtatttg tggctaatcg ggcccgtcaa gatgactacc tagtactggc aacgactcag
     8521 ttaggccttc agccacaagc gatcattcaa ctatacgccc gaagatggca aattgagaat
     8581 tactttaaag ttgccaagca atacttgcgg ctcgacaaat cacaagttca aaattatgac
     8641 gggctttgtg gccatttagc aattgtcatg atgacttatg acctattagc ttggcaggaa
     8701 cggcaaaatc aggatgatcg caccattggg gatttattct ttataatgaa cgaagccatg
     8761 ccagatattg agttgtctca agcactggta tggcttctaa attcgttaaa aacgattatt
     8821 aatcatgaag tttatgcaag aagagcccaa attattcaga tgatgaatca gttcttcaca
     8881 tttttgccga aacggttagt ttcgctgtta acagcgagct aaatggttaa attaattaaa
     8941 atatgccctg tgataccaag ggatcagtct gtcttcatac tttcaagttt cagttactaa
     9001 gtaacggatt gattatttgt taacgaatga gttaatgatt tttaagatac catagacgat
     9061 cgccaaaatg aggttgataa tggcgatcgt gtttatcacc ggttcgaacc aatgagctga
     9121 cccggccccc aataaaatta gcatcagtcc aattaggatc gtcggccaaa agatcttccg
     9181 gaggatccag aaaacgggga tcagcaagat tatcactatc gtactgaacg tcagcggcac
     9241 aatcattttc accactcctc ccaaggtacc ttaattataa tcctcccctg aaaataaaat
     9301 cctttcttct tgaacggttt ctcattggat ccttaaataa aattaggcgt actggccgtc
     9361 aaagttaaga tctgaattaa tttaagggtg tagcaccgtt aactagccct ggtcactttt
     9421 gacaagttaa gtcgctttcc ttaaaattaa atttatctta gcgattttta attaaggagg
     9481 aacgccccga tgacgaactt aactaacctg tcgcccgccg agtttcgccg cctggtccgg
     9541 acgggggatt ttaccagccc gaccagcggc tactgccccg gatacaccca ggccaacctg
     9601 gtgatcgtcc cgcaacgtta cgcttacgac ttcttgttat tggcccagcg gaatccacgc
     9661 ccctgcccgg ttttagaggt cagcgatgcc ggcagccggg gcttgactaa ttttgctacg
     9721 gatgtcgacc tggctaacga ctttcccaag taccgggttt accggggagg ggagctaaat
     9781 gaagaagtaa cgtcggtcga acgcctgtgg caagacgact tcgtttcctt tttgatcggt
     9841 tgtagctttt cgtttgaggc cgaattgctg gcggccggca tcgaggtgcg ccacatcacc
     9901 gagggggtca acgtgtcgat gtataacacc aacttacccc tgcaaggtac cggtgccctg
     9961 cacggtaaca tggtggtgtc gatgcgacca atcccggcta gccaggtagc taaggcggtg
    10021 gaggtgacgg cggcgatgcc tagggtccac ggggcaccaa tccacgttgg cgacccagct
    10081 tcgttaggga tcaaagacct gtcccacccc gattacggtg acccggtcac gatcaaagac
    10141 ggggagctgc cggtcttttg gccctgtggg gtgaccccgc aaaacgcgat catgcaaagc
    10201 aagctcccgc tggtgattac ccacgccccc ggccacatgt tgatcaccga cgtgttaaac
    10261 gccgacctga agggtaacgg gtgatcaatt aaaactttga tgaccaagcc ttgacacccc
    10321 cctatagaag gggtatatta ttagcaatca gatgtccttt aagctagtcc cgtgaggcta
    10381 gaaaggtaac ggagaaattg cccggtttgg gccaccgttg aacccttcac ttgcggaatg
    10441 cgagtggagg gttttctttt gggacagccg agaataaacc atcaaattgc tccagcgagg
    10501 gtaaaatggt tacgctttcc ggattaaaga cggtagtagt aacgattaac ctccctggag
    10561 cagcgctaag ttgccccggg gaggtttttt ctttggggca cagaaaagga gaatgtctca
    10621 tgaccaccca actcgttgaa caactggttt ctttaccaca ctttgtttcc gtggaggatt
    10681 taacgactga ccaagtcaac gccctgattg cccgggccga agaattcaag aacggcgcgc
    10741 cggcaccgaa acttagccag ccggtttacg tgaccaacat gttctttgaa aactcgacgc
    10801 gcacccacac ctcctttgcg atggccgaaa agaagctggg cttaaccgaa atccccttcg
    10861 acacgtccca ctcctcgatt aaaaagggcg aaacccttta cgacacctgc ctaaccctgg
    10921 atgccttagg cgttgaccta acggtgatcc gggcgtccga aaacgactac tacctgccac
    10981 tgatcaaccc gggggcgggc cactacctag gcctggggat cgtgaacggt ggtgacggct
    11041 ctggtcaaca cccatcccaa tgcatgctag atatcatgac catccacgaa cactttggcc
    11101 actttaaggg cctcaaggtg gcgatcgtcg gcgacatcac ccactcccgg gtggcccgct
    11161 ccaacatgga aatcttaaac aagctcggcg ccgaagtgta cttctccggc ccggaatact
    11221 ggtacgacca cgcctttgac aagtacggca agttcttacc gatcgacgaa ctggtcgaag
    11281 aagtcgacgt catgatgctc ttacgggtcc aacacgaacg ccacgccggc gatgcccacg
    11341 aaggggactt ctcggcggcg gactaccaca agcaatacgg gatcaacgag gaacgctacg
    11401 ccctgctcaa gccggacacg atcatcatgc acccgggccc gattaaccgc ggcgttgaac
    11461 tagccgactc cttagtcgaa gccccaaagt cggccttcgt cgcccaaatg aaaaacgggg
    11521 tcttcatgcg gatggcgatg ttagaagccg tactgcgcgg tcgtaaactg gggggcttgg
    11581 aataatgaaa accctaatta aaaacgggac cgtctacaac gatggccgcc tggttaaaga
    11641 agacgtcctg gtggaagacg ggatcatccg ggcaattggc aaggacctcc acgagtacct
    11701 agacgatgat tacgacgaac tcgacgccgg caacctcctg gtcagccccg gtttagtcga
    11761 cgtgcacgtc cactaccgcg agccgggcca aaccgaaaag gaaacgatca ggaccggttc
    11821 ggccgccgcg gctcacggtg gttttaccac ggtcggggcg atgccaaacg tcgacccggt
    11881 accggacacc ccggccaagg tggcccagat ggtcgctaaa aataagcagg acggcctggt
    11941 tcacatcgcc cagtactcgg cgatcacgac cgaccggact agcgacgagg tggttgacat
    12001 ggccggcgtc aagcgggccg gggccttcgc cgtttccaac gacggtaacg gggtccaagc
    12061 ggcggggacg atgtaccggg ccatgcaggc cgctaaggcg gtgggcctac cgttagccgc
    12121 ccacgtggag gacgaatcgc tgctctttgg cggtgtgatg acgggagggg accggtcccg
    12181 ctacctggga ctacccggcg ccccggaagt agtcgaatcc gcccaagtcg ctcgcgacct
    12241 cgccctggcc aaggccactg gggtccacta ccacgtctgt cacgtttcca ccaaggacag
    12301 cctggagatg atccacttcg ccaagcaaaa cggcgtccgg gtgacttgcg aggcgactcc
    12361 acaccacctg ctcttgtccg accagtgcat tgacggtcac gatagtaact acaagatgaa
    12421 cccaccgcta cgccacgaag cagaccggcg cgccctggtg gcggctttaa acgatggcac
    12481 ggttgacatg atcgctaccg accacgcccc gcacaccgaa gaagataagg gtcgtgactt
    12541 ttgctgcgcg gccaacggga tcaccggcag tgaaacggcc ttcgccctgt tgtacaccaa
    12601 gttagtcaag accgggctct tgaagctaga gcggctcttg gacctgatgg ccaccaaccc
    12661 cgccgaagcc tttaacctga ccgaagccgg tcacttagag gtcggtaagc ccgccgacat
    12721 cgccgtcttt gacctcaacc acccctacgt tatcgaccag cgtgactacc tgtccaaggg
    12781 gatcaattca ccctttaccg ggatgaccgt ctacgggcaa accgtgatga cgatggttga
    12841 cggccaagtg gtttaccaac gaaaggagaa ctaacgtgca acgctacctc gtcttagaag
    12901 acggcacaac ttaccgtggc accgcctttg gggccgacca agccaagacc ggtgaagtgg
    12961 tctttaccac cggcatgacc ggctaccaag aggcgatcac cgaccagtcc tttgccaacc
    13021 agattctggt cttcaccaac cccctgatcg ggaattacgg cgtcaacctc gatgatgacg
    13081 aatccctgct tcccgagatc aaaggggttg tttgccgcaa actggcccgc gtcgccacta
    13141 actggcggat gcaagacgac ttggccaact tcttgaccca gcgggggatt ccggggctgg
    13201 aggggatcga cacccgggcc ctggttaaaa agctgcgcca acacggaacc ctgcgggggc
    13261 ggctggtcga tgacttaacc gacctggacc aagtagtggc cgcattaaag caagccaccc
    13321 cgatgaaaaa catcatcccg ctcgtttcca ccaagagccc ctatcccaac ccgggcacca
    13381 agcgcaacat cgtggtggtc gactttggga tcaagcactc catcttacgg gaactggcta
    13441 agcgcgactg taacgtgatc gtcttacccc acaccgcgac ggccacccag gtcctaaatt
    13501 tgcacgccga cggggtcctc ttgtccaacg gccccggcga cccactggaa atgacggcgg
    13561 ccgcggaaat ggttaaagaa gttgaacaac acctgcccgt ctttggtatt tgcatgggtc
    13621 accagatctt ggccctagct aacggcgcca agacggtcaa gatgaagttt ggccaccgcg
    13681 gtttcaacca cccggtcaaa aacgtggcga ccggcgaggt taacttcacc tcgcaaaacc
    13741 acgggtacgc cgtcgacacc acctccatcg accccgaccg gttactgatc acccacgtcg
    13801 aaattaacga cggcaccgtc gaggggcttc gccacaagca ctacccggcc ttttcggtcc
    13861 aattccaccc ggatgcggcc ccgggaccgc acgatgcgga gcagctcttt gatgacttta
    13921 ttaacctggt cgaccaacgc aagaaaggac gaaactaatg ccgaagcgca ctgatattca
    13981 caagatcatg gtgattggct cgggcccgat catcatcggc caagccgctg aatttgacta
    14041 ttccggtacc caggcctgcc tagccctaaa ggaggagggt tacgaaaccg ttttggtcaa
    14101 ctccaacccg gccacgatca tgaccgacaa ggagattgcc gaccacgtct acatcgaacc
    14161 gctgacggtg gcggccttga cccggatttt gcgccaggag gcccccgacg ccctcttacc
    14221 cactttaggg gggcaaattg ggttgaacct agccgtcgcc ctttcaaaga ccgggatcct
    14281 agacgaactg ggaattgaac tactggggac caaactggcc tcgattgacc aggccgagga
    14341 ccgcgaaaag ttcaaggaat tgatgcaaga actgggtgag ccggtcccgg cctccttgac
    14401 cgtcagcacg gttgaacagg ccctggcctt tgctaaaacc gttggctacc cggtgatcgt
    14461 ccgccccgcc tttacgatgg gcgggaccgg gggtgggcta gccaacaacg aggccgaact
    14521 cgccgaaatc gccaagaatg gccttgaact atcgccggcc acccagtgct tgatcgaaaa
    14581 gtcgatcgcc ggctacaagg aaatcgagtt tgaggtcatg cgcgacgccg ccgataacac
    14641 gatggtcgtt tgttgcatgg aaaacttcga tccggtcggc atccacaccg gcgactcgat
    14701 cgtctttgct cccagccaaa ccctggccga ccgcgagtac caacgcttac gggactgcgc
    14761 gttaaaactg atttcggcct taaagatcga ggggggctgc aacgtccaac tggccctcga
    14821 tcccaactct tacgattaca acgtgattga agtcaacccg cgggtcagcc gttcctcggc
    14881 cctggcttct aaggccaccg gctacccgat cgccaagcta gccgccaaga ttgcggtggg
    14941 cttaaccctc gacgaaatca agaacccggt caccaagacg acctacgccg agtttgaacc
    15001 agcccttgat tacgtggtcg ttaagctccc ccgctggccc tttgacaagt ttaccaaggc
    15061 cgaccggcgc ctaggtagcc agatgaaggc gaccggggaa gtgatg
//
