GCA_024137985.1 - 5 region(s) - antiSMASH results

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaOMKAACAG_1 (original name was: gnl|Prokka|OMKAACAG_1)

Region	Type	From	To
Region 1.1	RiPP-like	374,801	386,168
Region 1.2	T3PKS	1,815,713	1,856,882
Region 1.3	terpene	2,906,773	2,927,654
Region 1.4	cyclic-lactone-autoinducer	3,153,583	3,174,288

gnlProkkaOMKAACAG_6 (original name was: gnl|Prokka|OMKAACAG_6)

Region	Type	From	To	Most similar known cluster		Similarity
Region 6.1	NRPS	17,602	60,682	mutanocyclin/leuvalin/tyrvalin	NRP	46%

Region	Type	From	To	Most similar known cluster	Similarity
Region 1.1	RiPP-like	374,801	386,168
Region 1.2	T3PKS	1,815,713	1,856,882
Region 1.3	terpene	2,906,773	2,927,654
Region 1.4	cyclic-lactone-autoinducer	3,153,583	3,174,288
Region 6.1	NRPS	17,602	60,682	mutanocyclin/leuvalin/tyrvalin	NRP	46%

No secondary metabolite regions were found in these records:: gnlProkkaOMKAACAG_2 (original name was: gnl|Prokka|OMKAACAG_2); gnlProkkaOMKAACAG_3 (original name was: gnl|Prokka|OMKAACAG_3); gnlProkkaOMKAACAG_4 (original name was: gnl|Prokka|OMKAACAG_4); gnlProkkaOMKAACAG_5 (original name was: gnl|Prokka|OMKAACAG_5)

Compact view

gnlProkkaOMKAACAG_1 - Region 1 - RiPP-like

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Location: 374,801 - 386,168 nt. (total: 11,368 nt) Show pHMM detection rules used

RiPP-like: (strepbact or Antimicrobial14 or Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or Lactococcin or Antimicrobial17 or Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaOMKAACAG_1 - Region 2 - T3PKS

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Location: 1,815,713 - 1,856,882 nt. (total: 41,170 nt) Show pHMM detection rules used

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaOMKAACAG_1 - Region 3 - terpene

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Location: 2,906,773 - 2,927,654 nt. (total: 20,882 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaOMKAACAG_1 - Region 4 - cyclic-lactone-autoinducer

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Location: 3,153,583 - 3,174,288 nt. (total: 20,706 nt) Show pHMM detection rules used

cyclic-lactone-autoinducer: (TIGR04223 or AgrB)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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resistance

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Gene details

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Gene overview

KnownClusterBlast

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

gnlProkkaOMKAACAG_6 - Region 1 - NRPS

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Location: 17,602 - 60,682 nt. (total: 43,081 nt) Show pHMM detection rules used

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

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resistance

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

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Similar known gene clusters from MIBiG 3.1

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Legend

NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 17601 - 60682:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg6_36

Search NORINE for peptide: strict or relaxed

AMP-binding (447..839): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: DYFTLGLVVK
Nearest Stachelhaus code(s):: Leu DYFTFGLIIK (68% 8Å match); OMe-Trp DAFTLGCVFK (56% 8Å match)
Stachelhaus code match:: 70% (weak)