LOCUS       c00005_gnlPro..        13819 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MBKGOMDH_5.
ACCESSION   c00005_gnlPro..
VERSION     c00005_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 15:56:57
            Original ID  :: gnl|Prokka|MBKGOMDH_5
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 13819
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13819
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[362:3819]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      363..3819
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..13819
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..13819
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(363..1130)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_1"
                     /sec_met_domain="Fer2_3 (E-value: 3.2e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 1.1e-10, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 6.1e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIAAGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1171..3129)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_2"
                     /sec_met_domain="FAD_binding_2 (E-value: 6e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 1.7e-37,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3151..3819)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg5_3"
                     /sec_met_domain="SucD_FumR (E-value: 3.2e-13, bitscore:
                     42.2, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFGGPEWINTYAHG
                     LHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIKATLSSRYMIYT
                     GLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGFSNVWCSAFYIL
                     AVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFISVPVSVLLGIIK
                     "
     CDS             4074..4325
                     /locus_tag="ctg5_4"
                     /transl_table=11
                     /translation="VLDADFAAARAGVLDVAAFLDRVDRGEGEADFRYHALMDVLPLLS
                     ASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4358..5143
                     /locus_tag="ctg5_5"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5177..5410)
                     /locus_tag="ctg5_6"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLCRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(5842..6549)
                     /locus_tag="ctg5_7"
                     /transl_table=11
                     /translation="MNKLLSTLILSAGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYNGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSATYYS
                     NSGLKFGNQQINQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             complement(6552..6689)
                     /locus_tag="ctg5_8"
                     /transl_table=11
                     /translation="MNYKHNILTLNIFNCLRIPNPIGEFQIRYSSTSTYIESCIILLRY
                     "
     CDS             6732..6917
                     /locus_tag="ctg5_9"
                     /transl_table=11
                     /translation="MTGQSLLFIGFMIDLASFSLLDGFQIRYKLPSKRNNKYEENTDTF
                     NRDGKLCCFLGGSDRF"
     CDS             6874..7584
                     /locus_tag="ctg5_10"
                     /transl_table=11
                     /translation="MGSFAVSSEAATVFNYYTPGTDNYNSTIHGFYLSLGSSSLAPSDS
                     SSPSSLSGEIRLDSFTLRGAANNLGANVTYGFLVLNGSDNSVIGWSTNTGTTAAGINLT
                     FSFSSLDGSPLLLDAALTYRFLAVSQSVMGLMQDTSKTYLYAAGGTAAPTANTEGDTVT
                     ISGGLTAPGIRGHYDAEGTPGDSVVITGANGTNTFSLLSPIFTEIRGEMVPEPATVSLG
                     LLGLAALMMRRRRA"
     CDS             complement(7686..8123)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_11"
                     /sec_met_domain="Acetyltransf_1 (E-value: 3.9e-08,
                     bitscore: 26.1, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGPIAVLPEYQRRGIGRRMIGYTRNRAREMGFRAIFLYGDPDYSS
                     HCGFVPAETLGIRTADNRYAAALQVCALQRGSLSGLKGRYVEAAVYHMDEKRAAEFDRH
                     FPVKKKLSGIASQKRFQQIAAMRRKPDTAPCPRKSRTFRRA"
     CDS             complement(8176..8376)
                     /locus_tag="ctg5_12"
                     /transl_table=11
                     /translation="MTIALRTEQSADHAETEHVTREALWNYFVPGCNEHYLLHIMRVSP
                     SFIPEQDAVAIHGSRIVGKHR"
     CDS             complement(8390..9595)
                     /locus_tag="ctg5_13"
                     /transl_table=11
                     /translation="MRGIFLVSCFLGGSVLLAGCREENNSPRPATEDAARITSARQWGE
                     SRSALQKRELDRAAGPALPIPDDLPSRELVGTTRQIHQLIEASGNPARFESYTETVPAA
                     GASLRMVAIPGGTFLMGSPAEEPHRKPDEGPQHKVSISPFWISETEIPWELYTAFMENG
                     RPRAKDGQLLEEQPDDELWDSVTQPTAPYTAMNLGMGHGYEHGLPAISMSHHAASKFCE
                     WLSAQTGHYYRLPTEAEWEYACRAGSPGAYSYGNGEASLDQYAWYWNNSNDRYQKTGSK
                     KPNKWGLRDMHGNVAEWVLDSYVPDAYGKRSGLPAKDPLVIIPGAPHIVRGGSWEDDPD
                     SLRSAARRASTPAWNRQDPQNPKSIWYLTDGGMIGFRVVRPMNIPDVMTMHRLWNFSKG
                     EP"
     CDS             complement(9619..10548)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg5_14"
                     /sec_met_domain="adh_short_C2 (E-value: 1.4e-74, bitscore:
                     243.1, seeds: 358, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTGRTPVHSGKMKRPDSSPPPRFSPLFFHSRHALSPYGFLRGQV
                     HFKLAGTVKNGFTVGSMQKLAGKTAIVTGAGRGIGNAVAHRFASEGARVILISRSPSSC
                     GGAAEEINKEFPDSCKAYPCDVADYAAVQETMAAILKDFPQIDILVNNAGITRDSLMLR
                     MKEEDWDAVLDTNLKSAFNTVKALQRVLMKSPAGRIINMSSVIGLVGNIGQANYAASKA
                     GLIGFTKSLAQEFAPRKVTCNAIAPGFISTEMSNAIPDNLKEEIVKKIPLKEQGSVEDI
                     AALTAFLASDDARYITGQVIACDGGMTM"
     CDS             complement(10493..10831)
                     /locus_tag="ctg5_15"
                     /transl_table=11
                     /translation="LAGVQDKESADNAVKTLQDIQKDIRHFLQLQDKLNDAEKEKEDAL
                     IEKMKKRMEMLDNRCRQEGKRLFEARYYGSAALKDILENSDEFSDLVEPDEDGAHPGAL
                     RENEEAGQ"
     CDS             complement(11074..12684)
                     /locus_tag="ctg5_16"
                     /transl_table=11
                     /translation="MLTIKNLTKSHAGRTLFRETEMTINWGERVALVGPNGAGKSTLFR
                     MILGEDTPDEGSISMDEYAIVGYLPQEASEPKDETVLEIALGITPEMEQAIHTIRTAEN
                     ANKTDTPEYAEAIDTFNAANGYQLEPKAKKILKGLAFRESDFHRPAREMSGGWIMRAYL
                     AKLLVLEPDLLMLDEPTNHLDLLSLLWLQRYLKNYPGAILMISHDRDFMDELVESVYDI
                     DNEELVEYRGNYSDFLQQKDVRFEQLQAAYRNQQKEIAHIQEFIDRFRSINSKAGQVQS
                     RIKQLEKMKIIQKPVARRKVFKFNFPQPPRSTQKVIELEKVCQSYGDRRVYENLDLLVE
                     RGERTVLVGPNGAGKSTLLKILAGIIPIDSGQRTPGTTTRIGYFSQARTENLNPENTVL
                     EEIMKCSAEIREEEARSILGSFLFRRLDVEKRVSVLSGGEKSRLSLVKFLVDPPNLLLM
                     DEPTTHLDLLSVEALVQALKHYEGTLVFISHDVHFIRSLAQKTLHVNRGTITAYAGGYD
                     YYLEKSGILDDEKGGITAE"
     CDS             12924..13514
                     /locus_tag="ctg5_17"
                     /transl_table=11
                     /translation="MSGLANAFLALLPPDQASLPAAGAEARWLADTAVVQSAAIARDNR
                     TVLFGWLNNILVNSNLRDRGLCWQVQQDLYRDLRRRPVKYFRIGLTIRDRGTGREHSCV
                     YVNAAGKGLQGSIVLDAWKNCGHLVTLTQKDREGGKWEEDWREPFVSKAFPEGHSYGME
                     HHLVWPGWARKRPMLVQRIFQSDQQNEAKAAAE"
ORIGIN
        1 atagacatca atgttgtctg tttgttagaa aatgttttcc tctcatgctg agcccttgac
       61 aggaggccat cccttccggg catcagtcca attcctgtaa tcaatgtttt tctttctcga
      121 agaaagatgg ggccgtcgct gtcggacggg gcctgcttag gtttcgtccg gcatttccaa
      181 gtacggtttc ctggattact gggtgccttc cagtgtaaca tttatttttt acgctgcgcg
      241 acgatgagga agcaactgtc tgatatttta ttcctggttc aaggaaacct gataatgaaa
      301 aaaactcccg acagccgatg ccgccgggag tttttacaga gcgtcttaag aaggaatctt
      361 ctttagaaac agaggccttc cttggcgttg gctcgcatga agtcgcggtt gaggcgggcg
      421 atgttgtcca cgctgatgcc tttcgggcag gcagcttcac attcatactg gttcgtgcag
      481 ttgccgaagc cttccgcttc catctgcttc atcatggcca ggacgcgctt ggaacgttcc
      541 ggctggccct gcggcagcag attgagatgg gcgatcttgg cggaggtgaa cagcatggcg
      601 gaggcgtttt tacaggaggc cacgcaggcg ccgcagccga tgcaggcggc cgcgtcaaag
      661 gcggcgtccg ccttcacttt ttccacggcg atgttgttgg cgttcggcgc ggaaccggta
      721 cgcacgtcaa tatagcctcc ggcggcgatg atgcggtcca gggcggagcg gtccaccatc
      781 aggtcccgca ggattgggaa agccttcgcg cggaagggtt caatccagac ggtatcgccg
      841 tccttgaact tgcgcatgtg aagctggcaa gtggtcacct ggcgttccgg cccgtgggga
      901 atgccgttga tggtcaggga gcacatgccg cagatgcctt cccggcagtc gtggtcaaaa
      961 tggatgggtt ccttgccttc cttgaccagg ccttcattga cgatgtccag catttccagg
     1021 aaggaggcgt ccaccggaat gtccttggcg gcataggtct caatgcggcc cttggcttcc
     1081 cggttttcct ggcgccagac cttgagagtg agattgagtg ttttagccat gttataatct
     1141 ttcttttgag tgttaatgta ttggctatct ttacttgtag ctgcggatgg caaggtgcac
     1201 gttctcgaag gtcagcggtt ccttgtggag aacaggcagg ctgtccacgc cagtgtattc
     1261 ccaggcggct acataggcgt attcatcgtc gttgcgcttg gcttcgccgt ccggcagctg
     1321 gtattccacg cggaagtggg cgccgcagga ttcctggcgg ttcagggcgt catagcagag
     1381 cagctgggcg aattccagga agtcggccac gcggcaggct ttttccagtt ccgcgttgat
     1441 gccgtccgcc gtgccggtta cgcgcacgtt ttcccagaat tccttgcgga gctggggaat
     1501 gcgttcaatg gcgtgggtca ggctttcttc cgtgcgggcc atgccgcagt cttcccacat
     1561 gatgaggccc agttcccggt ggaaggagtc caccgtcttg gtgcccttca cattcaggag
     1621 cttgttgatg cgttccttca cttcgtcttc cgcagccttg aattccgggg cggcggtggt
     1681 gacggcaccg ggcttggtgg tcgtcaggta agcgggcagc gtggcgggaa tgacgaagta
     1741 gccgtcagac aggccctgca tcagggcgga ggctcccagg cggttggcgc cgtggtcgga
     1801 gaagttggct tcaccgagga cgtgcagccc cttcacgttg gacatgaggt tgtagtccac
     1861 ccacaggccg cccatggtgt agtgggaggc ggggtagatc atcatgggcg tttcatgggg
     1921 gtcgtcgtcc gtgatttctt cgtacatgtc aaacagattg ccgtattggc cgtcaatcca
     1981 ttcgcggccc atgcgcttga tttcatccgc aaaatccagg aagacgccct tgccggtgac
     2041 ggccacgccg cggccgtcgt cgcaggcttc cttggcggcg cgggaggaaa tgtcgcgcgg
     2101 agccaggttg ccgaaggagg gatacttgcg ttccaggtag tagtcccgtt cttcttcggg
     2161 aacatcggaa ggcttgattt ccttcttacg gattttttct gcggtttcac gggacttggg
     2221 cacccagatg cggccgctgt tgcggaggga ttccgacatc agcgtcagtt tggactggta
     2281 gtcgcctttg accggaatgc aggtggggtg gatttgcgtg aagcaggggt tggcgaagaa
     2341 ggcaccacgc ttgtaggctt tgtaggcggc agtgacgttg caacccatcg cgttggtgga
     2401 caggaagaac acgttgccgt agccgcccgt gcagagcagg acggtatccc ctgcgtagga
     2461 tttgatttcg ccggtaacca gattgcgggt gacgatgccc ttggcttcgc cgtccaccag
     2521 caccagatcc atcatttcat ggcgcgagaa catttcaatg tgtcccttgg ccacttcctt
     2581 ttccagggcc tggtaggcac ccagcaggag ctgctggccc gtctgtccgc gtgcgtagaa
     2641 ggttcgcttg agctgggcgc cgccgaagga gcggttgtcc agcaggccgc cgtattcacg
     2701 gccgaaggga acgccctggg ccacacactg gtcaatgatg ttggaggaga cttccgccag
     2761 acggtagaca ttggcttcac gggcgcggaa gtcgccgcct ttaacggtgt cgtaaaacag
     2821 gcggtaaacg gagtcgccgt cgttctggta gttcttggct gcgttaatgc cgccctgggc
     2881 cgcaatggag tgggcgcggc ggggactgtc ctggtagcag aagcatttga cgttgtagcc
     2941 aagttcggca agcgtggcgg cagcggaggc gccagccagg ccggaaccta ccacaagcac
     3001 cgtgtacttg cgcttgttgt tcggattgat cagtttggac tcaagtttgt acttggacca
     3061 tttgtcctga atagggccgg agggaatttt ggcatccggc atccagtcgc ttacgggaaa
     3121 attaatcatg actttgagag gagttgatgg ttatttgatg atacccagaa gaaccgagac
     3181 cggcacggag atgaagccca ggcagataat cgcgccgtag gcgatggcga taaagttgta
     3241 gaagggccgg attttgcggg aatcgacgcc cacagtctgg aagatggact gtaccccgtg
     3301 gcgcagatgg ctgaacagca tcagaacggc caggatgtag aaggcggagc accatacgtt
     3361 ggagaatccg gtcacgatca tcttgtacac gtcaaaggtt tccaccgtac cgtcggaaat
     3421 gaaggtggtg aactgggcgg ggtcgtatcc cacgcgcagg gtgtactggt acaggtggta
     3481 gatcaggaac accaggacgg tcaggccggt atagatcatg tagcgggagg agagcgtcgc
     3541 cttgatggtg ttcttgaaca cgtagggttc gcgggccgca tggttttcca gcttcagctg
     3601 gatggtcagc cagacgtgga tgatgaagat caccgcaagc cccgcgcgga ttccccagag
     3661 ggctgcttcc ggcatggagt gcaggccgtg ggcgtaggtg ttgatccatt cagggcctcc
     3721 gaagatgaga aggttgcctg ccaggtgtcc cgcaaggaac aagaccaaac ataaccccgt
     3781 cagagccaca atgattttgc ggccgatgga ggatgtcacg aatgtacata tggtttttac
     3841 tagtgcattc ataggcgctc taatgaaata aatgcgtctt cacaggatgc ccggttcaag
     3901 cccggatggc aagcctcttc ttgaatttcc ggcgcttttc ggatttttga aaagccgggg
     3961 aaagaggttg ctgtttatca gtttggaatg gttatcattt tgttgcctgt tccggcttga
     4021 cgaggctttc cgcataggcg tatcgtctgt gcatgaaaag aagtaaaaag gaagtgctgg
     4081 acgcggattt cgcagcggcg cgcgccggcg ttctggatgt ggccgcattt ctggaccggg
     4141 tggaccgcgg ggaaggggag gcggatttcc gttaccatgc cctgatggat gttcttcccc
     4201 tcttgtccgc atccggcccc ggacgtgtcc gggccattct ggaagccctt tcctacaggg
     4261 atgacaccgt gccggaaacc gccgcagcca aagcggcctg cggagccccg aacctcagca
     4321 aataaaaatg atggctttca tagaacctca tatacatatg gtgtgccgca ccacggacga
     4381 ataccgggcc atggcgcagg ccggctgcct ggcggtaggg gaaccggcgt tctgggccgg
     4441 ttacgaccgt tcgtccgcgg acggtttccg ggattatttc gtacagctta cggaatgcga
     4501 acccgccagg gcggccaagt tcggcatgga ccattacaca tggctgtgca tcaatcccaa
     4561 ggaggcgcag gacgtggctt tcgcgcggga tgtgatgaaa ctgattccgg agttcattga
     4621 ccggcccaat gtcctcggca tcggggaaat agggctgaac cggaatactt cccatgaaat
     4681 gactattttt gaagagcatc tggatctggc ggtgcgcctc aaccagcttg tgctgattca
     4741 cactccccat ctggaagaca agcttaaggg gaccgtaatg attctttccg ccctgaaaaa
     4801 ccgtccggat ctggaccctt gccgcgtgtt ggtggatcac tgtgaggaac ataccttccc
     4861 gctggtgaag gaggccggtt actgggccgg gctgaccctt tatcccacca gcaagctgaa
     4921 tcccaagcgg gcggcggata ttctggaatt gtacggaatg gaccgtgtct gggccaattc
     4981 cgcggcggac tggggggatt ccgatcccct ggcgctgacg gccctggcct gcgagctgcg
     5041 caggcgcggt ttttcccggc aggaaacgga acgtcttctc ctggaaaatc cggagacatt
     5101 catgggacag tccccgaagt tccggaaagt gtcgtcccgc taattccgcc cgaggcgcgg
     5161 cggagggtac ggccctctag tccccgtccg ggaaaaagac ggtgaggacg gcgcccagga
     5221 tgaccgccgc gtcatccaga aggcccagcc tgccgattcc gtcaaacagg aattcgtcgg
     5281 gagtcaggat gtaggcgccg gcggcggcca gaaggcatat attccgtttg ttgaaaaaac
     5341 gcggttctcc ttttctgctt ttgaaatacc ggcacaggcg cagtagcagc tgctgttttt
     5401 gaagattcat ggacgggaac gggggataaa ggttcaagct cagccatttt cccactcctt
     5461 ttccctgttt cggggaagga gtctgttgcc gacggacgga aaccgcagcg atccggaccg
     5521 tgcggggaaa tggattgctg aaaggatggg ctgttccgga tgctgaggga agccgggctt
     5581 tgcatgctcc ggttccggct gtcccggcat gggaaaaagg ggcgtgtacg gaagtggggc
     5641 ggggtcggaa gctcttgaaa tgaccctccc gggggagcct gaatgccatt tccccgtcaa
     5701 gtgctggccg tgagggtacc gcagcaaatg gaagcttctt cccccctgtt ttttccggca
     5761 gatgtttgaa cggataagga aaaggccggc tcacgatttt gtgagccggc ctttgaatat
     5821 agggaggcgg acggtacagg cttatgccct gcggcggcgc atcatcagcg cggccagtcc
     5881 cagcaggccc agggaagccg tggcgggttc cgggatgctg gcgatttcac tcatcagttg
     5941 accaacttgt tcctgggaaa ggagggagtc gtggatgtag agctgttcga tggattcagc
     6001 cagtcctgcg tccatgagaa tctgattaat ttgctggttg ccgaatttca ggccgctgtt
     6061 ggaatagtac gtagcgctgt cgccaaaata gatgcgggtg ccaagatctc cggtgactac
     6121 ggaaatggtc agggaacctt ccgtgcccag cggggtgtca acgacgggcc cgttgtatga
     6181 ggtgttgttc cataatccct ggagtttccg gtccgtgttc aggcccacgc cccagcttac
     6241 actgctgttt ttggcgttaa acagagcggt ataggcgtcc ggagtgttga ttttggacag
     6301 gtcaagaacc atcgtcacag acataacgtc gcggttgttg gcaccgtatc cgttgaaggt
     6361 tatcccggat aacgtcagat tgctgtcgtc agacgtgatg gaaacggaat ctttcagggt
     6421 gccgaaatcc gccgtttggg aggcaaagtc cgaatatccc acgatggagc tatccagcag
     6481 agaggtagcc gcggtagcgc ttaggctcat gccggccgaa agaatcaggg tggataataa
     6541 tttattcatg gtcagtatct taataaaatg atgcaagatt caatgtatgt acttgtgctt
     6601 gaataacgaa tttggaattc cccaatcgga tttggaatcc gcaagcaatt aaaaatatta
     6661 agagttagta tattgtgttt ataattcatt gaaaataatg attttttaat atctctggtc
     6721 cttttgtcaa gatgacgggt cagtctttgt tattcattgg tttcatgatt gatttggcct
     6781 ctttttcatt acttgacgga ttccaaattc gctacaagtt gccatccaaa aggaataata
     6841 aatatgaaga aaacactgac acttttaatc gcgatgggaa gctttgctgt ttcctcggag
     6901 gcagcgaccg tttttaatta ttacactccc ggtacggata attacaatag taccatccat
     6961 gggttttatc ttagcctggg gtcttcttcc ctggctcctt ccgattcctc ttctccctcc
     7021 tccctgtccg gagagatcag actggacagt tttacgctgc gcggagccgc caacaatttg
     7081 ggcgctaatg tcacttacgg cttcctggtg ctgaatggct ccgacaattc ggtcatcggc
     7141 tggagcacca atacgggaac tactgcagca gggattaatc tgacgttcag tttttcttcc
     7201 ctggatggtt ctcccctgct tcttgacgcg gcattgacat accgcttcct ggccgtgagc
     7261 cagtccgtga tgggcttgat gcaggatacg tctaaaacgt atttatatgc tgcggggggg
     7321 acagccgccc ctactgctaa cacggaagga gataccgtaa cgatcagcgg cggattgact
     7381 gctcccggca tccgcggcca ttatgacgcc gagggaacgc ctggtgattc tgttgttatt
     7441 acgggagcca acggaaccaa tactttcagc ttattatctc cgattttcac ggaaatccga
     7501 ggggaaatgg tgccggaacc agccacggtt tccctgggcc tgctgggact ggccgcgctg
     7561 atgatgcgcc gccgcagggc ttgagcttcc tgatggcgaa aaatcggcgg atgagagctg
     7621 ttcttgcgga acagctcttg ttttttatat ccagagagga agaattactc atccgcatgc
     7681 gggattcatg ccctccggaa ggtacgggat ttccgggggc agggggccgt atccggtttt
     7741 ctccgcatgg cggcaatttg ctggaaacgt ttttgagacg caataccgga aagctttttc
     7801 tttaccggaa aatgccggtc aaattcggca gcgcgctttt cgtccatatg gtacacggca
     7861 gcttccacat agcggccttt caggccggat agggaacccc tttgcagcgc acagacctgg
     7921 agggccgccg catacctatt atccgccgtt ctgatgccca gcgtttccgc gggaacgaat
     7981 ccacagtgtg aagagtagtc cgggtcgccg tacaggaaaa tggcacggaa gcccatttca
     8041 cgcgcccggt tcctggtgta gccgatcatc cgccgtccta ttccccggcg ctggtattcc
     8101 ggaagaacgg caatgggccc catgcccagc acttcatatt cttttccatc gtctgccctg
     8161 atgacggacg ttgcatcaac gatgtttccc gacgatgcgg ctgccgtgga tggcgactgc
     8221 atcctgctcc gggatgaagg aaggactgac gcgcatgata tggagcaggt aatgttcatt
     8281 gcagccgggg acgaaatagt tccagagcgc ttctctcgtg acatgttccg tttcggcatg
     8341 gtctgcggat tgttccgttc ttaatgcaat ggtcatgaag ggttgttctt tacggctccc
     8401 ccttggagaa attccagagg cggtgcatcg tcataacgtc cggaatgttc atggggcgca
     8461 ccacgcggaa cccgatcatg cctccgtccg tcaggtacca gatgctttta gggttttgag
     8521 gatcctgacg gttccaggcg ggggtgctgg cgcggcgcgc agcgcttctc aggctgtccg
     8581 ggtcgtcttc ccacgaaccg ccgcgaacga tgtgaggggc gccggggatg atgaccaagg
     8641 ggtctttcgc gggcaagccg ctccgtttgc cgtaggcatc cggaacgtaa gagtccaaaa
     8701 cccattccgc cacatttccg tgcatgtccc ggagtcccca cttatttggt tttttagagc
     8761 ctgttttctg gtagcggtca ttggagttgt tccagtacca ggcgtactgg tccagagagg
     8821 cttccccgtt tccgtaagaa taggcgccgg gggagccggc ccggcaggcg tattcccatt
     8881 ccgcctccgt gggcaggcgg tagtaatgcc cggtctgggc gctcagccat tcgcagaatt
     8941 tgctggcggc gtggtgggac atggagatgg cgggcagacc gtgttcatag ccgtggccca
     9001 tgcccaggtt catggcggtg tagggggcgg taggctgcgt aacggagtcc cacagttcgt
     9061 catccggctg ttcctccaga agctgaccgt ccttggcgcg cggacgcccg ttttccatga
     9121 aggccgtata aagttcccag gggatttccg tttccgagat ccagaaggga gagatgctca
     9181 ctttatgctg cggtccttcg tccggtttcc ggtgcggctc ttccgcggga ctccccatga
     9241 ggaacgttcc tcccggtatg gcgaccatgc gcagggaagc tcccgccgcg ggaaccgttt
     9301 ccgtgtagga ttcaaaacgt gccggatttc cggaagcttc aatgagctga tggatttggc
     9361 gcgtcgtgcc gaccagctcc cgggacggca ggtcatccgg aatgggaagg gcaggaccgg
     9421 cagcgcggtc cagttcccgt ttttgcagcg cggatcggct ttctccccat tggcgtgcgc
     9481 tggtaatgcg cgcggcatct tccgtggccg ggcgggggga attattttct tcccggcacc
     9541 cggccagcag gacgcttcct cccagaaagc aggaaacaag gaaaatgccg cgcatggaat
     9601 ggtgaaaacc ggaatgccct acatcgtcat gcctccgtcg caggcaatga cctgcccggt
     9661 gatgtaacgg gcatcgtcag aggcaaggaa ggccgtcagg gcggcgatat cttccacgga
     9721 accttgttct ttcaaaggta ttttcttaac gatttcttcc ttgagattgt cgggaatggc
     9781 attggacatt tccgtggaga tgaagccggg agcaatggcg ttgcacgtga ctttgcgcgg
     9841 agcgaattcc tgagccagtg atttggtgaa accgatgagg cccgccttgg aagcggcgta
     9901 attggcctgg ccgatgttgc cgacgagacc gatgacggag ctcatgttga tgatacgccc
     9961 ggccggggat ttcatgagaa cgcgctggag ggccttgacc gtattgaacg cgcttttcag
    10021 gttggtgtcc agaacggcat cccagtcttc ctctttcatg cggagcatca gggagtcccg
    10081 cgtgatgccg gcgttgttca ccaggatgtc aatctgcggg aagtctttca aaatggcggc
    10141 catggtttcc tgaacggccg cgtaatccgc tacgtcgcag gggtaggcct tgcaggaatc
    10201 cggaaattcc ttgttgattt cttctgcggc ccccccgcag ctggatggac tgcggctgat
    10261 caggatgacc ctggctcctt ccgaagcgaa gcggtgcgcg acggcattgc cgattccgcg
    10321 gcccgcgccg gtaacgatgg ctgttttacc tgctaacttt tgcatgctgc ccacagtaaa
    10381 cccgtttttc acggttccgg caagcttgaa atggacttgg ccgcgcagga acccatacgg
    10441 ggaaagggcg tgccgggaat gaaaaaagag gggggagaaa cggggcgggg ggctactgtc
    10501 cggcctcttc attttcccgg agtgcaccgg ggtgcgcccc gtcttcatcc ggttctacca
    10561 ggtcgctgaa ttcatccgaa ttttccaaaa tgtcctttaa ggcggcggaa ccgtaatagc
    10621 gggcctcaaa caggcgtttg ccttcctgcc tgcagcggtt gtccagcatt tccattcgtt
    10681 ttttcatttt ttctatcaag gcgtcttctt tctccttttc cgcatcgttc aatttatcct
    10741 gaagctggag gaaatgccgg atgtccttct gaatgtcctg cagcgttttg acggcgttgt
    10801 ccgcgctttc cttgtcctga acgcctgcca acgtctgctg gatattgatg gcaaaggaaa
    10861 aggcctggtt gatcagggat tccgcggaag gaattttttc cgccggagcc gctgctgtgg
    10921 ggaagccgtt ccggcggccg tttcaccaaa tgcaagagag gctccggaca gaagcgcaga
    10981 atataagaga ggaacaagaa aagccttcat cctgttcttt taaggcagga tgaaatccac
    11041 ggcaaggaaa aaggggaaac tgaaaaaaga gccttattcc gccgtgatgc cgcctttttc
    11101 atcgtccaga atgcctgact tttccagata gtagtcatat ccgcctgcgt aggcggtgat
    11161 ggtcccccgg ttcacatgca gggttttttg tgccagggaa cggatgaagt gcacatcgtg
    11221 ggagatgaag accagtgttc cttcataatg cttcagagcc tgcaccaggg cttctacgga
    11281 caaaaggtcc aggtgggtgg tcggctcgtc catcagcagg aggttgggcg gatccaccag
    11341 gaatttgacc aagctgagcc gcgatttttc cccgccggaa agaacgctga cgcgtttttc
    11401 cacatccagc ctccggaaca ggaaggaacc caggatggaa cgcgcttctt cctcccggat
    11461 ttcagcgctg catttcatga tttcctccag cacggtattt tccggattca ggttttccgt
    11521 tcgcgcctgg gagaagtagc cgatgcgcgt cgtggtaccg ggagtgcgtt gtccggagtc
    11581 aatggggatg atgcccgcca ggattttgag aagagtggat ttgcccgcgc cgttcgggcc
    11641 tacaagaaca gtgcgctccc cgcgttccac cagcaggtcc aggttttcat aaaccctgcg
    11701 gtcgccatag gattggcaga ctttttccag ctcaatgact ttctgggtgc tgcgcggagg
    11761 ctgggggaag ttgaatttaa atactttcct gcgggctacc ggtttttgaa tgattttcat
    11821 cttttccagc tgcttgatgc ggctctggac ttgcccggct ttggaattga tggagcggaa
    11881 acggtcaata aattcctgaa tgtgcgctat ttccttctgc tggttgcggt aggccgcctg
    11941 aagctgctcg aagcgcacgt ccttttgttg gaggaagtcc gagtaattgc cgcggtattc
    12001 caccagttct tcgttgtcga tgtcgtacac gctttccacc agctcatcca tgaaatcccg
    12061 gtcgtgggaa atcatcagga tggctccggg gtagtttttc aggtatcgct ggagccacag
    12121 cagggacagg aggtccaggt ggttggtagg ttcgtccagc atcaggaggt ccggctccag
    12181 gacaaggagc ttggccaggt acgcgcgcat gatccagccg ccggacattt cccgggcggg
    12241 gcggtggaag tcgctttccc gaaaggccag ccctttgaga attttcttgg ctttgggctc
    12301 cagctggtaa ccgttggcgg cgttgaaggt gtcaatggct tccgcgtatt ccggcgtatc
    12361 cgttttgttg gcgttttccg ccgtccggat ggtgtggatg gcctgttcca tttccggcgt
    12421 gatgcccagg gcgatttcca gaacggtttc atccttcggt tcgctggctt cctggggaag
    12481 atagcccacg atggcgtatt catccatgct gatggagcct tcgtccggcg tgtcttctcc
    12541 cagaatcatg cggaacaggg tggatttgcc tgctccgttg gggccaacca gagccacccg
    12601 ttccccccag ttaatggtca tttccgtttc cctgaacaag gtccgtccgg cgtgggattt
    12661 tgtgagattt ttgatcgtca gcatggtgaa gagaggatgt attctaccgg gatggaaagg
    12721 ggaaggcaag agccgtcagg gcggaggcag gcatttttga aagctttact ggatttttac
    12781 gcgtagtctg ctagccttgg cgcgccatgc cgaccacgca gacattcagg cttttgcttg
    12841 ctgccgccct tttgtgcgga tggagttcct gctgtactcc tccggcggag gattatatac
    12901 aacaacctta cgtgcagcag caaatgtccg ggctggctaa tgccttcctg gcgctgctgc
    12961 cgccggatca ggcctctctt cccgctgccg gagcggaggc caggtggctg gcggacacgg
    13021 ccgtggtcca gtccgcagcg attgcccggg acaacaggac tgtgctgttt ggctggctga
    13081 acaatattct ggtcaattcc aacctgcgcg acagggggct gtgctggcag gtccagcagg
    13141 atttgtaccg ggacctgcgc cgccgccccg tgaagtattt ccgcataggg ctgacgattc
    13201 gagaccgtgg aacgggcagg gagcacagtt gcgtgtatgt caatgccgcg gggaagggat
    13261 tgcagggctc cattgttctg gatgcctgga agaactgcgg gcatctggtg acgctgaccc
    13321 agaaggaccg ggaaggcggc aaatgggagg aggactggcg ggaaccattt gtttccaagg
    13381 cctttccgga gggccattcc tacggcatgg aacatcacct ggtctggccc gggtgggcca
    13441 ggaaacgccc catgctggtt cagcggatat ttcagtccga tcagcagaat gaggcgaagg
    13501 cggccgctga ataaagggga agcctgatcc ggcaggaacc ggcacacggt gctgcgccgc
    13561 ggcggtttgc ggtatccgcc gtttttaagg aaaatcccgg cgaatcggca aatggcggag
    13621 ggaatccgga ctcagggcaa ataaaaacgc actcagtgcg tacaccgagt gcggattaat
    13681 tggataattt gctagtgttg cagggcaaaa ccccgctgca aacttacttg cccttggcct
    13741 gcacaaccgg agcgggagca ggagcggtgg tttgctgttg ctgctgctgc tgggagcaag
    13801 aagcgaccag gcaagcggc
//
