LOCUS       c00012_gnlPro..        14342 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LGMPEGIM_12.
ACCESSION   c00012_gnlPro..
VERSION     c00012_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 16:25:47
            Original ID  :: gnl|Prokka|LGMPEGIM_12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14342
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14342
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[852:4342]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      853..4342
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14342
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14342
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(2..298)
                     /locus_tag="ctg12_1"
                     /transl_table=11
                     /translation="MNPPHRSSSVHRSAVPGYRKWYFGAGGSPGRRGMEAAPEPDPLPF
                     EEIHEHAEITVGPPSTSADGYSAHGTFTIPEGAEGKKLYGTCSLFLGVDDWGSL"
     CDS             complement(853..1620)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_8"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: -1.5; E-value: 8.6)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_2"
                     /sec_met_domain="Fer2_3 (E-value: 1.5e-23, bitscore: 74.4,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_8 (E-value: 4.9e-11, bitscore: 34.5,
                     seeds: 153, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 2.8e-06, bitscore: 19.2,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKTLNLTLKVWRQENREAKGRIETYAAKDIPVDASFLEMLDIVN
                     EGLVKEGKEPIHFDHDCREGICGMCSLTINGIPHGPERQVTTCQLHMRKFKDGDTVWIE
                     PFRAKAFPILRDLMVDRSALDRIIASGGYIDVRTGSAPNANNIAVEKVKADAAFDAAAC
                     IGCGACVASCKNASAMLFTSAKIAHLNLLPQGQPERSKRVLAMMKQMEAEGFGNCTNQY
                     ECEAACPKGISVDNIARLNRDFMRANAKEGLCF"
     CDS             complement(1661..3619)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 176.1; E-value:
                     4.2e-54)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_3"
                     /sec_met_domain="FAD_binding_2 (E-value: 2.7e-54, bitscore:
                     176.1, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 7.8e-38,
                     bitscore: 120.8, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINFPVSDWMPDAKIPSGPIQDKWSKYKLESKLINPNNKRKYTVL
                     VVGSGLAGASAAATLAELGYNVKCFCYQDSPRRAHSIAAQGGINAAKNYQNDGDSVYRL
                     FYDTVKGGDFRAREANVYRLAEVSSNIIDQCVAQGVPFGREYGGLLDNRSFGGAQLKRT
                     FYARGQTGQQLLLGAYQALEKEVAKGHIEMFSRHEMMDLVLVDGEAKGIVTRNLVTGEI
                     KSYAGDTVLLCTGGYGNVFFLSTNAMGCNVTAAYKAYKRGAFFANPCFTQIHPTCIPVK
                     GDYQSKLTLMSESLRNSGRIWVPKSRETAEKIRKKEIKPSDVPEEERDYYLERKYPSFG
                     NLAPRDISSRAAKEACDDGRGVAVTGKGVFLDFADEIKRMGREWIDGQYGNLFDMYEEI
                     TDDDPHETPMMIYPASHYTMGGLWVDYNLMSNVKGLHVLGEANFSDHGANRLGASALMQ
                     GLSDGYFVIPATLPAYLTTTKPGAVTTAAPEFKAAEDEVKERINKLLNVKGTKTVDSFH
                     RELGLIMWEDCGMARTEESLTHAIERIPQLRKEFWENVRVTGTADGINAELEKACRVAD
                     FLEFAQLLCYDALNRQESCGAHFRVEYQLPDGEAKRNDDEYAYVAAWEYTGVDSLPVLH
                     KEPLTFENVHLAIRSYK"
     CDS             complement(3641..4342)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: SucD_FumR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_4"
                     /sec_met_domain="SucD_FumR (E-value: 1.7e-13, bitscore:
                     42.0, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNALVKTICTFVTSSIGRKIIVALTGLCLVLFLAGHLAGNLLIFG
                     GPEWINTYAHGLHSMPEAALWGIRAGLAVIFIIHVWLTIQLKLENHAAREPYVFKNTIK
                     ATLSSRYMIYTGLTVLVFLIYHLYQYTLRVGYDPAQFTTFISDGTVETFDVYKMIVTGF
                     SNVWCSAFYILAVLMLFSHLRHGVQSIFQTVGVDSRKIRPFYNFIAIAYGAIICLGFIS
                     VPVSVLLGIIK"
     CDS             4543..4815
                     /locus_tag="ctg12_5"
                     /transl_table=11
                     /translation="MKRSKKEVLDADFAATRAGVLDVAAFLDRVDRGEGEADFRYHALM
                     DVLPLLSASGPGRVRAILEALSYRDDTVPETAAAKAACGAPNLSK"
     CDS             4848..5633
                     /locus_tag="ctg12_6"
                     /transl_table=11
                     /translation="MVCRTTDEYRAMAQAGCLAVGEPAFWAGYDRSSADGFRDYFVQLT
                     ECEPARAAKFGMDHYTWLCINPKEAQDVAFARDVMKLIPEFIDRPNVLGIGEIGLNRNT
                     SHEMTIFEEHLDLAVRLNQLVLIHTPHLEDKLKGTVMILSALKNRPDLDPCRVLVDHCE
                     EHTFPLVKEAGYWAGLTLYPTSKLNPKRAADILELYGMDRVWANSAADWGDSDPLALTA
                     LACELRRRGFSRQETERLLLENPETFMGQSPKFRKVSSR"
     CDS             complement(5667..5900)
                     /locus_tag="ctg12_7"
                     /transl_table=11
                     /translation="MNLQKQQLLLRLFRYFKSRKGEPRFFNKRNICLLAAAGAYILTPD
                     EFLFDGIGRLGLLDDAAVILGAVLTVFFPDGD"
     CDS             complement(6332..7039)
                     /locus_tag="ctg12_8"
                     /transl_table=11
                     /translation="MNKLLSTLILSVGMSLSATAATSLLDSSIVGYSDFASQTADFGTL
                     KDSVSITSDDSNLTLSGITFNGYGANNRDVMSVTMVLDLSKINTPDAYTALFNAKNSSV
                     SWGVGLNTDRKLQGLWNNTSYSGPVVDTPLGTEGSLTISVVTGDLGTRIYFGDSTTYYS
                     NSGLKFGNQQIDQILMDAGLAESIEQLYIHDSLLSQEQVGQLMSEIASIPEPATASLGL
                     LGLAALMMRRRRA"
     CDS             7077..7310
                     /locus_tag="ctg12_9"
                     /transl_table=11
                     /translation="MYLCLNNEFGIRYDRFIRALMNHGRNDGFVPLPFTGCDSYNPIRI
                     MFSISWFPFYSRSSSSFPLHAETVLQHYYPGL"
     CDS             7270..7899
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_10"
                     /sec_met_domain="Glycos_transf_2 (E-value: 3.8e-37,
                     bitscore: 119.1, seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQKPFFSIIIPAYNLENYIAAALQSVLVQTFQDFEIIIVDDGSSD
                     ETVSIIQSFHDPRIRLVSQVNGGVSRARNAGMKKAVGAYIAFMDGDDYWYPEHLELAAD
                     FFNRHPEILAYANRYMRDELAAIPPRPPSYPESIRRLGIRGVLFMNSSSVILNSFLASR
                     LPPLGRSDALWGRRPVLDTVHAGDRPDRAGRLRHLHLQAESFFRHA"
     CDS             7892..8308
                     /locus_tag="ctg12_11"
                     /transl_table=11
                     /translation="MHNEHYQHISLHSLIAPLLNELEAMKNPKWQFAVHYLVIRELHPK
                     RLLSLNVEERISLTGRIRKIMHPCLNRPFLDSYMKACSARAGMEQSFSALMDRTMFSCK
                     WLDRLERMGRFLFFRLQTNNGTESKHQDPVRSRS"
     CDS             8305..8499
                     /locus_tag="ctg12_12"
                     /transl_table=11
                     /translation="MNIVYATDDNGALGTGVSIVSLMENLPLGVHADIYIMTDGLSGDN
                     TARFHSLQQDTISICTSLT"
     CDS             8496..9251
                     /locus_tag="ctg12_13"
                     /transl_table=11
                     /translation="MKDKYTDFPVGSKWSAATYYRLGLAGELPATVERALYVDIDTIFN
                     RDISPMYESEFGDCLIAGVFTTEDLSEESFSRWKREMNLDRDSIYINAGVILYHIGRIR
                     EERFESQVLSWAKNNIHRLSWQDQDILNVCYQQRILLLHPMWNICDGAIWSIRWEGVKS
                     FRNNPLKPADLLEAARRPGIIHYWGHPKPWHPNSIRQDYGLFYKYWKKSPWKDDIRDFR
                     KQNDTGRMFISKMRCLLGKGKRLLQGKHQ"
     CDS             9574..10728
                     /locus_tag="ctg12_14"
                     /transl_table=11
                     /translation="MLILEAGEKGQYGFAAPTDAIEVSDEDALITQVFKTAVPGLPGQN
                     GIRQGENAELKNLTAESGTFAGAVNANGGINIPLTVGAATDTSAVNRLYAAGLAAVTDA
                     FSLRCYPLPADCSSSNGTVFKTDKEPNSLYFNVPPNSSFTVKCGLVTNARPMHNYSSIR
                     GWVAPLRLPSVSAKFTTRFGQMKTVVRMGRDRDAFTLVPDQAAGGYRIGEIIDITFDHV
                     RDAAAGGYHIRVREIYYSNAEQKWKMKTTQALAPETSSNNGYPVCVYAVVYEQYQDGGY
                     DTEDRGALWLLHGGNSTRGCVKIATVRGVHCFENIYPFSGYYLDMENANSWALAGAFLP
                     ATMHLHCNNVNPAYYGFSSMESNIIVSEAVEDFVDPEAETTTED"
     CDS             complement(10782..12344)
                     /locus_tag="ctg12_15"
                     /transl_table=11
                     /translation="MEESRVKKSLLNARVNLIFYVLILLISFFSRKIFLNCLGADFVGL
                     TGTLMSLLNFLNLAELGISTAIGYVLYKPIFEHDETRINEIISVLGYMYRWIGRIIIAA
                     GVALSCFLPVIFPSTGFSYGIIYFAYYSFLASSLIGYFANYRQTLLGADQRNYVVAFYF
                     QTASIIKIICQMLSAWYTGSYYLWIGIELFFGIIYSFILNWKINQVYPWLKSNVALGKE
                     LFKKYPEVTKYTKQLFMHRLGSFFQFQMTPFLVYAFVSLQMAAYFGNYSTIVDKLHLLV
                     NNLLGSTEAGVGNLIAEGNEGKIRKVFSELFSLRMLIAGTVCFPLYQLLEPFITLWLGA
                     EYILPREIMLLLVIRLFITITRGVVDQFLYGYGLFWDVWAPLAESVINISVAIIGGYLW
                     GLPGVLLGGVSSLILIVGIWKPFMLYNWGFRKNVMSYWFQFGYQLALVSISAVFMGWIW
                     KFVPLQPSASFFFWFLCAFLMAVSYGGVTVLLMYCGTQGMRGMVRRALEMAGTRLPWRK
                     KTE"
     CDS             12763..13923
                     /locus_tag="ctg12_16"
                     /transl_table=11
                     /translation="MAAYEMACSLSSLDWDIHVLTRPLDSPEEPFRSRPYSPLTTLPDT
                     LTKNSARLREYLDGFLKDFRPDVIIYHSWADWCREELLDAARDSGIPFFLRSHGAATNF
                     RSFFRFNYPPFFGLKKWLRSFFQIRRNILNVCRKSPLNRLVFLDPYGTLFKSFDYYCAS
                     RSKLAHYSCIPNTFPALKRTAPFFREKYGLSSAPVFTCPAGASMRKRQLLFIRHVKRSR
                     LRHIIFLFLIPQRNAYAEQMEQAIGDDPRFRILYRLPRLEVEAAIMESDAVFLYSYQEQ
                     QPLSILEAMSCGVPWFAPDAGALSTLEGGIVLKNASPSALEKAVESLTDEKTRKLLGSK
                     GRRQWEARFAPDAVNQEWEQLLFSSIRPEGKPPFASSIVREHLPTC"
ORIGIN
        1 ccaggcttcc ccagtcgtcc accccaagga agagcgagca ggtgccgtag agttttttgc
       61 cctccgctcc ttccgggatg gtgaatgtcc cgtgcgcgct gtacccgtcc gccgacgtgc
      121 tcggcggtcc cacagtgatt tcagcgtgtt cgtggatttc ttcaaatggc agcgggtcgg
      181 gctccggagc tgcctccatg ccccgcctgc cggggctgcc gccggctcca aagtaccatt
      241 tccggtagcc gggaacggca gaacgatgga cggaggagga acgatgaggc ggattcatca
      301 ggtattcaag agtcgggggt aatgaaggaa gcgagggggg ccgccctttc ctgatcgttt
      361 tatcaatagt atgatctgaa gtcggtgtcg atagaatttt atttgtatgt ttttgatttt
      421 ttataaaaga tggtcattat tttacacgaa aagataatat tataattctt acgttcagtg
      481 cattccctta atagacatca atgttgtctg tttgttagaa aatgttttcc tctcatgctg
      541 agcccttgac aggaggccat cccttccggg catcagtcca attcctgtaa tcaatgtttt
      601 tctttctcga agaaagatgg ggccgtcgct gtcggacggg gcctgcttag gtttcgtccg
      661 gcatttccaa gtacggtctc ctggattact gggaaccttc cggtgtaaca tttatttttt
      721 acgctgcgcg acgatgagga agcaactgtc tgatatttta ttcctggttc aaggaaacct
      781 gataatgaaa aaaactcccg acagccgatg ccgccgggag tttttacaga gcgtcttaag
      841 aaggaatctt ctttagaaac agagaccttc cttggcgttg gctcgcatga agtcgcggtt
      901 gaggcgggcg atgttgtcca cgctgatgcc tttcgggcag gcagcttcac attcatactg
      961 gttcgtgcag ttgccgaagc cttccgcttc catttgcttc atcatggcca ggacgcgctt
     1021 ggaacgttcc ggctggccct gcggcagcag attgagatgg gcgatcttgg cggaggtgaa
     1081 cagcatggcg gaggcgtttt tacaggaggc cacgcaggcg ccgcagccga tgcaggcggc
     1141 cgcgtcaaag gcggcgtccg ccttcacttt ttccacggcg atgttgttgg cgttcggcgc
     1201 ggaaccggta cgcacgtcaa tatagcctcc ggaggcgatg atgcggtcca gggcggagcg
     1261 gtccaccatc aggtcccgca ggattgggaa agccttcgcg cggaagggtt caatccagac
     1321 ggtatcgccg tccttgaact tgcgcatgtg aagctggcaa gtggtcacct ggcgttccgg
     1381 cccgtgggga atgccgttga tggtcaggga gcacatgccg cagatgcctt cccggcagtc
     1441 gtggtcaaaa tggatgggtt ccttgccttc cttgaccagg ccttcattga cgatgtccag
     1501 catttccagg aaggaggcgt ccaccggaat gtccttggcg gcataggtct caatgcggcc
     1561 cttagcttcc cggttttcct ggcgccagac cttgagagtg agattgagtg ttttagccat
     1621 gttataatct ttcttttgag tgttaatgta ttggctatct ttacttgtag ctgcggatgg
     1681 caaggtgcac gttctcgaag gtcagcggtt ccttgtggag aacaggcagg ctgtccacgc
     1741 cagtgtattc ccaggcggct acataggcgt attcatcgtc gttgcgcttg gcttcgccgt
     1801 ccggcagctg gtattccacg cggaagtggg cgccgcagga ttcctggcgg ttcagggcgt
     1861 catagcagag cagctgggcg aattccagga agtcggccac gcggcaggct ttttccagtt
     1921 ccgcgttgat gccgtccgcc gtgccggtta cgcgcacgtt ttcccagaat tccttgcgga
     1981 gctggggaat gcgttcaatg gcgtgggtca ggctttcttc cgtgcgggcc atgccgcagt
     2041 cttcccacat gatgaggccc agttcccggt ggaaggagtc caccgtcttg gtgcccttca
     2101 cattcaggag cttgttgatg cgttccttca cttcgtcttc cgcagccttg aattccgggg
     2161 cggcggtggt gacggcaccg ggcttggtgg tcgtcaggta agcgggcagc gtggcgggaa
     2221 tgacgaagta gccgtcagac aggccctgca tcagggcgga ggctcccagg cggttggcgc
     2281 cgtgatcgga gaagttggct tcaccgagga cgtgcaaccc cttcacgttg gacatgaggt
     2341 tgtagtccac ccacaggccg cccatggtgt agtgggaggc ggggtagatc atcatgggcg
     2401 tttcatgggg gtcgtcgtcc gtgatttctt cgtacatgtc aaacagattg ccgtattggc
     2461 cgtcaatcca ttcgcggccc atgcgcttga tttcatccgc aaaatccagg aagacgccct
     2521 tgccggtgac ggccacgccg cggccgtcgt cgcaggcttc cttggcggcg cgggaggaaa
     2581 tgtcgcgcgg agccaggttg ccgaaggagg gatacttgcg ttccaggtag tagtcccgtt
     2641 cttcttcggg aacatcggaa ggcttgattt ccttcttacg gattttttct gcggtttcac
     2701 gggacttggg cacccagatg cggccgctgt tgcggaggga ttccgacatc agcgtcagtt
     2761 tggactggta gtcgcctttg accggaatgc aggtggggtg gatttgcgtg aagcaggggt
     2821 tggcgaagaa ggcaccacgc ttgtaggctt tgtaggcggc agtgacgttg caacccatcg
     2881 cgttggtgga caggaagaac acgttgccgt agccgcccgt gcagagcagg acggtatccc
     2941 ctgcgtagga tttgatttcg ccggtaacca gattgcgggt gacgatgccc ttggcttcgc
     3001 cgtccaccaa caccaggtcc atcatttcat ggcgggagaa catttcaatg tgtcccttgg
     3061 ccacttcctt ttccagggcc tggtaggcac ccagcaggag ctgctggccc gtctgtccgc
     3121 gtgcgtagaa ggttcgcttg agctgggcgc cgccgaagga gcggttgtcc agcaggccgc
     3181 cgtattcacg gccgaaggga acgccctggg ccacacactg gtcaatgatg ttggaggaga
     3241 cttccgccag acggtagaca ttggcttcac gggcgcggaa gtcgccgcct ttaacggtgt
     3301 cgtaaaacag gcggtaaacg gagtcgccgt cgttctggta gttcttggcc gcgttaatgc
     3361 cgccctgggc cgcaatggag tgggcgcggc gggggctgtc ctggtagcag aagcatttga
     3421 cgttgtagcc aagttcggca agcgtggcgg cagcggaggc gccagccagg ccggaaccta
     3481 ccacaagtac cgtgtacttg cgcttgttgt tcggattgat cagtttggac tcaagtttgt
     3541 acttggacca tttgtcctga atagggccgg agggaatttt ggcatccggc atccagtcgc
     3601 ttacgggaaa attaatcatg actttgagag gagttgatgg ttatttgatg atacccagaa
     3661 gaaccgagac cggcacggag atgaagccca ggcagataat cgcgccgtag gcgatggcga
     3721 taaagttgta gaagggccgg attttgcggg aatcgacgcc cacagtctgg aagatggact
     3781 gtaccccgtg gcgcagatgg ctgaacagca tcagaacggc caggatgtag aaggcggagc
     3841 accatacgtt ggagaatccg gtcacgatca tcttgtacac gtcaaaggtt tccaccgtac
     3901 cgtcggaaat aaaggtggtg aactgggcgg ggtcgtatcc cacgcgcagg gtgtactggt
     3961 acaggtggta gatcaggaac accaggacgg tcaaaccggt gtaaatcatg tagcgggagg
     4021 agagcgttgc cttaatggtg ttcttgaaca cgtagggttc gcgggccgca tggttttcca
     4081 gcttcagctg gatggtcagc cagacgtgga tgatgaagat caccgcaagc cccgcgcgga
     4141 ttccccagag ggctgcttcc ggcatggagt gcaggccgtg ggcgtaggtg ttgatccatt
     4201 cagggcctcc gaagatgaga aggttgcctg ccaggtgtcc cgcaaggaac aagaccaaac
     4261 ataaccccgt cagagccaca atgattttgc ggccgatgga ggatgtcacg aatgtacata
     4321 tggtttttac tagtgcattc ataggcgctc taatgaaata aatgcgtctt cacaggatgc
     4381 ccggttcaag cccggatggc aagcctcttc ttgaatttcc ggcgcttttc ggatttttga
     4441 aaaaccgggg aaagaggttg ctgtttatca gtttggaatg gttatcattt tgttgcctgt
     4501 tccggcttga cgaggctttc cgcacaggcg tatcgtctgt gcatgaaaag aagtaaaaag
     4561 gaggtgctgg acgcggattt cgcagcgacg cgcgccggcg ttctggatgt ggccgcattt
     4621 ctggaccggg tggaccgcgg ggaaggggag gcggatttcc gctaccatgc cctgatggat
     4681 gttcttcccc tcttgtccgc atccggcccc ggacgcgtcc gggccattct ggaagccctt
     4741 tcctacaggg atgacaccgt gccggaaacc gccgcagcca aagcggcctg cggagccccg
     4801 aacctcagca aataagaatg atggctttca tagaacctca tatacatatg gtgtgccgca
     4861 ccacggacga ataccgggcc atggcgcagg ccggctgcct ggcggtaggg gaaccggcgt
     4921 tctgggccgg ttacgaccgt tcgtccgcgg acggtttccg ggattatttc gtacagctta
     4981 cggaatgcga acccgccagg gcggccaagt tcggcatgga ccattacaca tggctgtgca
     5041 tcaatcccaa ggaggcgcag gacgtggctt tcgcgcggga tgtgatgaaa ctgattccgg
     5101 agttcattga ccggcccaat gtcctcggca tcggggaaat agggctgaac cggaatactt
     5161 cccatgaaat gactattttt gaagagcatc tggatctggc ggtgcgcctc aaccagcttg
     5221 tgctgattca cactccccat ctggaagaca agcttaaggg gaccgtaatg attctttccg
     5281 ccctgaaaaa ccgtccggat ctggaccctt gccgcgtgct ggtggatcac tgtgaggaac
     5341 ataccttccc gctggtgaag gaggccggtt actgggccgg gctgaccctt tatcccacca
     5401 gtaagctgaa tcccaagcgg gcggcggata ttctggaatt gtacggaatg gaccgtgtct
     5461 gggccaattc cgcggcggac tggggggatt ccgatcccct ggcgctgacg gccctggcct
     5521 gcgagctacg caggcgcggt ttttcccggc aggaaacgga acgtcttctc ctggaaaatc
     5581 cggagacatt catgggacag tccccgaagt tccggaaagt gtcgtcccgc taattccgcc
     5641 cgaggcgcgg cggagggtac ggccctctag tccccgtccg ggaaaaagac ggtgaggacg
     5701 gcgcccagga tgaccgccgc gtcatccaga aggcccagcc tgccgattcc gtcaaacagg
     5761 aattcgtcgg gagtcaggat gtaggcgccg gcggcggcca gaaggcatat attccgtttg
     5821 ttgaaaaaac gcggttctcc ttttctgctt ttgaaatacc ggaacaggcg cagtagcagc
     5881 tgctgttttt gaaggttcat ggacgggaac gggggataaa ggttcaagct cagccatttt
     5941 cccactcctt ttccctgttt cggggaagga gtctgttgcc gacggacgga aaccgcagcg
     6001 atccggaccg tgcggggaaa tggattgctg aaaggatggg ctgttccgga tgctgaggga
     6061 agccgggctt tgcatgctcc ggttccggct gtcccggcat gggaaaaagg ggcgtgtacg
     6121 gaagtggggc ggggccggaa gctcttgaaa tgaccctccc gggggagcct gaatgccatt
     6181 tccccgtcaa gtgctggccg tgagggtacc gcagcaaatg gaagcttctt cccccctgtt
     6241 ttttccggca gatgtttgaa cggataagga aaaggccggc tcacgatttt gtgagccggc
     6301 ctttgaatat agggaggcgg acggtacagg cttatgccct gcggcggcgc atcatcagcg
     6361 cggccagtcc cagcaggccc agggaagccg tggcgggttc cgggatgctg gcgatttcac
     6421 tcatcagttg accaacttgt tcctgggaaa ggagggagtc gtgaatgtag agctgttcga
     6481 tggattcagc cagtcctgcg tccatgagaa tctgatcaat ttgctggttg ccgaatttca
     6541 ggccgctgtt ggaatagtac gtagtgctgt ctccaaaata gatgcgggtg ccaagatctc
     6601 cggtgactac ggaaatggtc agggaacctt ccgtgcccag cggggtgtca acgacaggcc
     6661 cgctgtagga ggtgttgttc cataatccct ggagtttccg gtccgtgttc aggcccacgc
     6721 cccagcttac actgctgttt ttggcgttaa acagagcggt ataggcgtcc ggagtgttga
     6781 ttttggacag gtcaagaacc atcgtcacag acataacgtc gcggttgttg gcaccgtatc
     6841 cgttgaaggt tatcccggat aacgtcagat tgctgtcgtc agacgtgatg gaaacggaat
     6901 ctttcagggt gccgaaatcc gccgtttggg aggcaaagtc cgaatatccc acgatggagc
     6961 tatccagcag agaggtagcc gcggtagcgc ttaggctcat gccgaccgaa agaatcaggg
     7021 tggataataa tttattcatg gtcagtatct taataaaatg atgcaagatt caatgtatgt
     7081 acttgtgctt gaataacgaa tttggaattc gctatgacag gttcattcgc gcgctgatga
     7141 atcatgggag gaacgatgga ttcgtccccc tgccattcac cggttgcgat agttacaacc
     7201 ccatcagaat catgttctcc atatcttggt tcccgttcta ttcacgaagc agttcatcat
     7261 tccccttaca tgcagaaacc gttcttcagc attattatcc cggcttataa tctggagaat
     7321 tatattgctg ccgcccttca gtcagtactg gttcaaacat ttcaggattt tgagatcatc
     7381 atcgtggatg acggttcttc cgatgagacc gtttccatca tccaatcttt tcatgacccc
     7441 agaatccgcc tggtttccca agttaacggc ggcgtgtcgc gggcgcgaaa cgcagggatg
     7501 aagaaggccg tgggggctta catcgctttc atggacggag acgattactg gtatcccgag
     7561 catctggagc tggcagccga ttttttcaac cgtcatccgg agatattggc ctatgccaac
     7621 cgctacatga gggatgaact ggcggccatc ccgccgcgcc ctccatctta tcccgaatct
     7681 atccggaggc tggggatacg gggagtgctt ttcatgaatt ccagcagtgt aatcctgaat
     7741 tcgtttcttg cgtcccggct tccccccctg ggaagaagcg atgccctatg gggaagacgg
     7801 cctgtactgg acacggtgca tgcgggggac aggcctgatc gggctgggag gctccgtcac
     7861 ctccatttac aggcagagag cttcttccgc catgcataat gagcattacc agcatatctc
     7921 cctccactcg ctcattgcgc ctctgctgaa tgagcttgaa gccatgaaaa atcccaaatg
     7981 gcaatttgcc gttcattatc tggtcatcag ggaattgcat cccaaaagac tgttatcgct
     8041 caacgtagag gaacggattt ccctgacggg cagaatcagg aaaatcatgc acccatgcct
     8101 gaaccggccg tttttggact cctatatgaa agcgtgttcc gcaagagcag gcatggaaca
     8161 atcattttcc gctctcatgg acagaaccat gttctcctgc aaatggctgg accgcctgga
     8221 aaggatggga cgcttcctgt ttttccggtt gcaaaccaat aacggaacag agagcaaaca
     8281 ccaagatcca gtccgttcac gatcatgaat atcgtatatg ctacagacga taacggcgcg
     8341 ctgggaacgg gcgtgagcat tgtgtccctc atggagaatt tgccgctcgg cgttcatgcc
     8401 gatatttaca tcatgactga cgggttaagc ggggataata cggcccgttt ccattccctg
     8461 caacaggata caatctccat ttgcacttca ttgacatgaa ggataaatat acggatttcc
     8521 ccgtcggttc caaatggtcg gcggcgacgt attaccgtct tggcctcgca ggggaacttc
     8581 ccgccacggt agaacgcgcc ctttacgtgg atattgatac cattttcaac agggacataa
     8641 gccccatgta tgaatccgaa ttcggagatt gcctcattgc cggcgttttc accacggaag
     8701 atttatccga ggaatctttt tcacgctgga agagagaaat gaatctggac cgggactcca
     8761 tttacatcaa tgccggcgtc attctttacc atatcggaag aatacgcgaa gaacgttttg
     8821 aatcccaggt tttatcctgg gcgaaaaaca atattcaccg cctttcctgg caggatcagg
     8881 atattttgaa tgtatgctat cagcagcgta tcctgttgct tcaccccatg tggaacattt
     8941 gcgacggggc tatctggtcc attcgttggg aaggcgtgaa aagcttcaga aataatcccc
     9001 tgaagccggc agacctgctg gaagccgcca ggcggccggg cattatccac tactggggcc
     9061 atcccaaacc ctggcatccc aacagtattc gccaggatta cggattgttc tacaagtatt
     9121 ggaagaaatc tccgtggaaa gatgacatca gggatttccg gaagcaaaac gataccggcc
     9181 ggatgttcat ctccaaaatg agatgcctcc tgggaaaggg taaacggctt ttacagggca
     9241 agcatcaata gaaatacgga gggagggctt tatattttcc tgatgcccag cctatttact
     9301 gcgtcgcctt ttatggggaa atgccagagc cggctatttt ttaacaagcc gacttaactc
     9361 ccctccggaa ttttcccgaa tccgggagaa accgtccgca tatgccttca ggaacgcctc
     9421 aacgttttat gcctgatgat ttttccggag ttttatcaat agtaaaaaaa tcattcattt
     9481 atgaaagttg ataccattaa gggaagttcc tatgtcatga cctgtacaaa agcttgtact
     9541 gtaagcgcca ttttcaattc cggagagacg tccatgctta ttctggaagc aggggaaaaa
     9601 gggcaatacg gttttgcggc cccgacggac gccatagaag tatccgatga agacgctttg
     9661 atcacccagg ttttcaaaac agccgttcca gggctgccgg gccagaacgg catcaggcaa
     9721 ggagaaaatg ccgaattaaa aaatctgacg gctgagtccg ggacttttgc aggggccgtc
     9781 aacgccaacg gaggcatcaa tatcccgctg accgtggggg cggcaacgga tacgtcagcg
     9841 gtcaaccgcc tgtacgccgc cgggctggct gccgtgacgg acgctttttc cctcaggtgc
     9901 tatccgctcc cggcggattg ctcgtcttcc aacgggacgg ttttcaaaac agacaaggaa
     9961 cccaattccc tttatttcaa tgtccctccc aattcctctt ttaccgtgaa atgcggcctc
    10021 gtgaccaacg cgaggcccat gcacaattat tccagcatcc gggggtgggt ggccccgctg
    10081 cgcctgccgt ctgtcagcgc taaattcacg accaggttcg gccagatgaa aacggtcgtg
    10141 cgcatgggaa gggacaggga cgcatttacg ctggtgccgg atcaggcggc gggcggctac
    10201 aggattgggg agattatcga tattacgttt gatcatgtcc gggacgcggc cgcagggggg
    10261 tatcacattc gtgtccggga gatttattat tccaatgccg agcagaaatg gaagatgaag
    10321 acgacgcagg ccctcgcgcc ggagacgtct tccaataacg gttatcccgt ctgcgtgtac
    10381 gcggtggttt acgagcaata ccaggacgga ggatatgata ccgaagacag gggagcgttg
    10441 tggctgctgc atggcgggaa ttccacccgc ggctgcgtca agatcgccac ggtgagggga
    10501 gtccattgct ttgagaatat ttatcccttt tccggatatt atcttgatat ggagaatgcc
    10561 aacagctggg cgttggccgg agcgttcctt ccggcgacga tgcacttgca ttgcaataat
    10621 gtcaatccgg cgtattacgg gttttcctcc atggagagca atatcattgt ctccgaggcg
    10681 gtggaggatt ttgttgaccc ggaagccgaa acgactactg aagattgagc ataaatgacg
    10741 cagcgtcccc attcccgatg cccggcaaca cctctgcgtc cctattcagt ttttttccgc
    10801 cacggcaacc gggttcccgc catctccagc gcacggcgca ccattccgcg catgccctgc
    10861 gtaccgcaat acattaaaag aaccgtcact ccgccataag agacggccat gagaaaggcg
    10921 cataagaacc agaagaagaa agatgcggaa ggctgcaggg gaacgaattt ccagatccag
    10981 cccatgaaca cggccgaaat cgaaaccagc gccagctggt aaccgaactg gaaccagtaa
    11041 ctcatcacat tttttctgaa tccccagtta tacagcatga agggcttcca gatgcccaca
    11101 ataagtatca ggctggagac tccccccaac aaaacgccgg gcaatcccca taagtaacct
    11161 ccgatgatcg ccacggaaat gttgatcacg ctttccgcaa gaggagccca tacatcccag
    11221 aacaaaccgt aaccgtataa aaactgatcc acaacccccc gcgtaatggt gatgaacagc
    11281 ctgatgacaa gcagcagcat gatttcccgg ggaaggatat attccgcccc cagccaaagc
    11341 gtgatgaatg gctccagaag ctggtaaagg gggaaacata ccgtcccggc aatcagcatg
    11401 cgcagggaaa acagctcact aaacactttg cggatttttc cctcatttcc ctccgcaatc
    11461 aagttgccca caccggcttc cgtactgccg agcagattat tgaccagaag gtgcagttta
    11521 tccacaatgg tggaatagtt gccgaaatag gccgccatct ggagggaaac aaaggcatat
    11581 accagaaacg gcgtcatctg aaactggaaa aagcttccca gccgatgcat aaacaactgc
    11641 ttggtgtatt tagtgacttc aggatatttt ttgaacagct ccttccccag ggccacattg
    11701 ctcttcagcc agggatagac ctgattgatc ttccaattca ggatgaagga ataaataatg
    11761 ccgaagaaca gttctatccc tatccataaa taatagcttc ccgtatacca tgcagacagc
    11821 atctggcata tgattttgat gatggatgct gtctggaaat aaaacgccac tacgtaattc
    11881 ctctggtccg ctcccaaaag ggtctgcctg tagttggcga aatacccgat cagggaagag
    11941 gccagaaagg aataataagc aaaatagatg attccatagg aaaagcccgt ggaaggaaaa
    12001 ataaccggca ggaaacagga aagcgctact ccagccgcga tgattatccg ccctatccac
    12061 cggtacatgt atcccagcac ggagataatt tcattaatcc tggtctcatc atgttcaaag
    12121 atcggcttgt aaagcacata cccgatagcc gtgcttatgc caagttccgc caaattgagg
    12181 aaattcagca gactcattaa tgttcccgtc aaaccgacaa aatcggcacc caggcaattc
    12241 aagaatatct ttcttgaaaa aaaggaaatg agaagaatca aaacataaaa aatgagattg
    12301 accctggcgt tcaacaggct tttctttacg cgggattctt ccatgttatt tattccatca
    12361 accttatcct ttcccgggag aagttaaaaa tatctgtttt attaataacc ggattattta
    12421 ttcaaccggc aatataccaa cggcatattg cggccatacg ggtacggaaa gcggtgccaa
    12481 tctagcacaa catcctgccg catcaatatc tttttatgaa gcctcagcca acaggcttcc
    12541 acaggggata gaaaccggtc agaatcgcct gttcccatga cgcctcctta tcgctcaccg
    12601 gataaaaaac aaattcctca tttttacagg ttccatggac cggaacagtt ccataaagtg
    12661 tccttgtttt attttttctt ttcatctaca ttaccgcccg tgagcaaggg cagggttctc
    12721 atcgttacat atgtttttcc tccggaggaa ggaggcgtag gcatggctgc ctatgaaatg
    12781 gcctgcagcc tgagctccct ggactgggat atccacgtcc tcacccgccc gctggattca
    12841 ccggaggagc ctttccgctc ccgcccatac agccctctca caaccctgcc ggacaccctg
    12901 acaaaaaaca gcgcccgttt aagggaatac ctggacgggt ttctgaaaga tttccggccg
    12961 gatgttatta tctaccactc ctgggcggac tggtgccggg aagaattgct ggacgcggcg
    13021 cgggattcag gcattccgtt tttcctccgc tcccatggtg cagctaccaa tttccgctct
    13081 tttttccgct tcaattaccc tcctttcttc ggcctgaaaa aatggctccg ctcctttttt
    13141 caaatacgca ggaatatcct caacgtatgc aggaaatcac cgttaaaccg tctcgttttt
    13201 ctcgaccctt acgggacact gttcaagagc tttgattatt actgcgcatc cagaagcaaa
    13261 cttgcccatt actcctgcat tcccaacaca ttcccggctc tgaaaagaac cgctcctttt
    13321 ttccgggaaa aatacggact ttcctccgcc cccgttttca cctgccctgc cggcgccagc
    13381 atgaggaaac ggcagcttct cttcatccgc catgtgaaac gctcccgtct gcggcatatc
    13441 atttttcttt ttctcattcc ccagcgcaat gcctacgcgg aacaaatgga acaggccatc
    13501 ggtgatgacc ccagattcag gattctctac aggctccccc gtttggaggt agaagccgcc
    13561 attatggaaa gcgatgccgt tttcctttac tcttatcagg aacagcagcc cctctccatt
    13621 ctggaggcga tgtcatgcgg cgttccctgg ttcgctccgg acgcaggagc tctttccacc
    13681 ctggaagggg gaatcgtcct gaaaaacgca tccccctccg cgctggaaaa agctgtggaa
    13741 tcgttgacgg acgaaaaaac acgcaaacta ctggggagta aaggccgccg gcaatgggaa
    13801 gcccgtttcg cccccgacgc agtaaaccag gaatgggagc aactgctttt ttcctccatc
    13861 cgcccggaag gaaagcctcc gttcgcgtct tccatcgtcc gggagcattt acccacctgc
    13921 taaccttgcc tccttttttc caatccatgc cgaccaaacg cctccgtccc gtattagcca
    13981 tagcagcgga cctccctctg ggccggctgc tgacgtcttt ccgtaacaaa gaccggcgta
    14041 cgattccctg gattttttcc ctttttcatg ctctggaatc tcaggaagat tttgacatcc
    14101 actggattac tctcagcaaa gccgtttccg ccgcggaaac catccggatg cgcaaccaga
    14161 ccatccacat ccttcccctg ggcagcatgg gcaggaatat cctgacggcc catttcctga
    14221 ccgtccggag aatacgcaag actctgaacg atatccagcc ggatctcctg cacgtatggg
    14281 gagtggagca ggcttacgct ctggcgggga ttaccttccg gggaaagaag ctcctttcct
    14341 ac
//
