LOCUS       gnlProkkaOLOPCOLM_7    12945 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OLOPCOLM_7.
ACCESSION   gnlProkkaOLOPCOLM_7
VERSION     gnlProkkaOLOPCOLM_7
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 13:22:02
            Original ID  :: gnl|Prokka|OLOPCOLM_7
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 818811
            Orig. end    :: 831756
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12945
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12943]"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12943
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /neighbourhood="10000"
                     /product="RRE-containing"
                     /protocluster_number="1"
     cand_cluster    1..12945
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="minimum(1,
                     [Bottromycin_Methyltransferase_RRE, Cyanobactin_D_RRE,
                     Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /kind="single"
                     /product="RRE-containing"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12945
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RRE-containing"
                     /region_number="2"
                     /rules="minimum(1, [Bottromycin_Methyltransferase_RRE,
                     Cyanobactin_D_RRE, Cytolysin_C_RRE, Goadsporin_CD_RRE,
                     Heterocycloanthracin_C_RRE, Lanthipeptide_LanB_RRE,
                     Lasso_Fused_RRE, Mycofactocin_RRE, NHLP_CD_RRE,
                     Other_Sactipeptide_rSAM_RRE, Pantocin_Microcin_RRE,
                     Plantazolicin_C_RRE, PlpY_RRE, PqqD_RRE,
                     Proteusin_Epimerase_RRE, Proteusin_Methyltransferase_RRE,
                     Quinohemoprotein_rSAM_RRE, Ranthipeptide_rSAM_RRE,
                     Stand_Alone_Lasso_RRE, Streptide_RRE, Subtilosin_rSAM_RRE,
                     Thiaglutamate_B_RRE, Thiaglutamate_G_RRE,
                     Thiaglutamate_I_RRE, Thiopeptide_F_RRE, Thuricin_rSAM_RRE,
                     Thurincin_rSAM_RRE, Trifolitoxin_RRE])"
                     /tool="antismash"
     CDS             156..956
                     /locus_tag="ctg7_865"
                     /transl_table=11
                     /translation="MKQRILTGVLAAIVFLFLVIVGELPFTILIYAMGSVALFELLRMK
                     KLKLVSLPGLIGLLLLWMFLLPSQYSFFEADGISKMEIALFAVLLLLTYTVLVKNTFTF
                     DEVGFITLAAIYIGMCFHYFIEIRNLDQYGLTYIFYACVVIWSTDSGAYFVGKSLGKRK
                     LWPEISPNKTVEGFAGGIVIALVLATIFQLVAQLPIPYIYLLLITLFLSVFGQLGDLVE
                     SALKRHYDVKDSGNILPGHGGILDRFDSFLFVMPFLYFLLALFS"
     CDS             1018..2169
                     /locus_tag="ctg7_866"
                     /transl_table=11
                     /translation="MKNICLLGATGSIGEQTLDVLRAHQDQFQLVSMSFGRNIDKAVPM
                     IEVFQPKFVSVGDLDTYHKLKQMSFSFECQIGLGEEGLIEAAVMEEVDIVVNALLGSVG
                     LIPTLKAIEQKKTIALANKETLVTAGHIVKEHAKKYDVPLLPVDSEHSAIFQALQGEQA
                     KNIERLIITASGGSFRDKTREELESVTVEDALKHPNWSMGAKITIDSATMMNKGLEVIE
                     AHWLFDIPYEQIDVVLHKESIIHSMVEFHDKSVIAQLGTPDMRVPIQYALTYPDRLPLP
                     DAKRLELWEIGSLHFEKADFDRFRCLQFAFESGKIGGTMPTVLNAANEVAVAAFLAGKI
                     PFLAIEDCIEKALTRHQLLKKPSLADIQEVDKDTRGYVNSILT"
     CDS             2182..3444
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M50"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg7_867"
                     /sec_met_domain="Peptidase_M50 (E-value: 2.5e-84, bitscore:
                     278.2, seeds: 56, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNTVIAFIIIFGTLVFFHELGHLLLAQRAGILCREFAIGFGPKIF
                     SFKKNETVYTIRLLPVGGFVRMAGEDPEMIEVKPGYTVGLLFNKEDQVEKVIINQKEKY
                     PDALVIEVETADLEHDMKITGYEQGKEDELSSFTVSETSFFIVDGEEVQIAPYNRQFGS
                     KPVWQRIKAIAAGPIMNFILAYVILVMLGLIQGVPSNEPMLGQLTDNGRAAEAGLKEGD
                     YIQSINGEKMRSWTDIVSAVKENPEKEMDVAVKRANKTLHISVTPEAVKDENKKTIGRF
                     GSYAPTEKGVLSAVAYGATSTVDIGNQILETFGNLVTGQFKINMLAGPVGIYDMTDQVA
                     KTGLVNLVRFAAFLSINLGIVNLLPIPALDGGRLLFLFIEAIRGKPINREKEAFVVFIG
                     VAFLMLLMLVVTWNDIQRLFL"
     CDS             3477..5171
                     /gene_functions="other (smcogs) SMCOG1162:threonyl-tRNA
                     synthetase (Score: 64.5; E-value: 9.9e-20)"
                     /gene_kind="other"
                     /locus_tag="ctg7_868"
                     /transl_table=11
                     /translation="MRQSLTLIPTLREVPADAEAKSHQLLLRAGFIRQNTSGVYSYMPL
                     AYKVIQNIQQIVREEMEKIDAVEMLMPALQQAETWQESGRWYTYGPELMRLKDRHGREF
                     ALGATHEEVITSLVRDEVKSYKRLPLTLYQIQSKFRDEKRPRFGLLRGREFIMKDAYSF
                     HASAESLDETYQKMYEAYSNIFARCGINVRPVIADSGAMGGKDTHEFMALSAIGEDTIA
                     YSDESQYAANIEMAEVLHQEVPSDEEPKALEKVHTPNVKTIEELTAFLQVSAEACIKSV
                     LFKADDRFVLVLVRGDHEVNDIKVKNLLHAEVVELATHEEVIQQLGTEPGFVGPVGIHQ
                     DVEVYADQAVKAMVNAVAGANEGDHHYKNVNVNRDAQIKEFADLRFIKEGDPSPDGKGT
                     IRFAEGIEVGQVFKLGTRYSEAMNATYLDENGRAQPMLMGCYGIGVSRTLSAIAEQHHD
                     EKGLIWPKSVAPYDLHILALNMKNDGQRELAEKLYADLKAEGYEVLYDDRAERAGVKFA
                     DSDLIGLPIRITVGKRADEGIVEVKIRQTGESTEISVDELSAFISKQ"
     CDS             5229..9593
                     /gene_functions="other (smcogs) SMCOG1194:DNA polymerase
                     III subunit alpha (Score: 939.6; E-value: 4.3e-284)"
                     /gene_kind="other"
                     /locus_tag="ctg7_869"
                     /transl_table=11
                     /translation="MPEVPSLMMFLGRDTVLMEQLSVNRRQFQILLQQINMTDDTFMTY
                     FEHGEIKKLTIHKASKSWHFHFQFKSLLPFQIYDTLTTRLTQSFAHIAKVTSSIEVQDA
                     EVSESIVQDYWSRCIEELQGISPPIISLLNQQKPKLKGNKLIVKTKTDTEAAALKNKYS
                     SMIQAGYRQFGFPDLQLDAEIFVSEQEVQKFREQKLAEDQERAMQALIEMEKKDKESDE
                     DQAPSGPLVIGYQIKDNEEIRTLDSIMDEERRITVQGYVFDVETRELKSGRTLCIFKIT
                     DYTNSILIKMFAREKEDAALMKSLKKGMWVKARGSIQNDTFVRDLVMIANDVNEIKAKT
                     REDSAPEGEKRVELHLHSPMSQMDAVTGIGKLVEQAKKWGHEAIALTDHAVVQSFPDAY
                     SAAKKHGIKMIYGMEANLVDDGVPIAYNAAHRLLEEETYVVFDVETTGLSAVYDTIIEL
                     AAVKVKGGEIIDKFEAFANPHRPLSATIIELTGITDDMLQDAPDVVDVIRDFREWIGDD
                     ILVAHNASFDMGFLNVAYKKLLEVDKAKNPVIDTLELGRFLYPEFKNHRLNTLCKKFDI
                     ELTQHHRAIYDTEATAYLLLKMLKDAAEKGIQYHDELNENMGQSNAYQRSRPYHATLLA
                     VNSTGLKNLFKLVSLSHIHYFYRVPRIPRSQLEKYREGLLIGSACDRGEVFEGMMQKSP
                     EEVEDIASFYDYLEVQPPEVYRHLLELELVRDEKALKEIIANITKLGEKLNKPVVATGN
                     VHYLNDEDKIYRKILISSQGGANPLNRHELPKVHFRTTDEMLEAFSFLGEKKAKEIVVT
                     NTQKVASLVDDIKPIKDDLYTPKIEGADEEIREMSYQRARSIYGEELPEIVEARIEKEL
                     KSIIGHGFAVIYLISHKLVKRSLDDGYLVGSRGSVGSSLVATLTEITEVNPLPPHYVCP
                     ECQHSEFFNDGSVGSGFDLPDKTCPHCGTPLKKDGHDIPFETFLGFKGDKVPDIDLNFS
                     GEYQPQAHNYTKVLFGEDNVYRAGTIGTVAEKTAYGYVKGYAGDNNLHMRGAEIDRLVQ
                     GCTGVKRTTGQHPGGIIVVPDYMDIYDFSPIQFPADATGSEWKTTHFDFHSIHDNLLKL
                     DILGHDDPTVIRMLQDLSGIDPKTIPTDDPEVMKIFQGTESLGVTEEQIGCKTGTLGIP
                     EFGTRFVRQMLEDTKPTTFSELVQISGLSHGTDVWLGNAQELIHNNICELSEVIGCRDD
                     IMVYLIYQGLEPSLAFKIMEFVRKGKGLTPEWEEEMKNNNVPDWYIDSCKKIKYMFPKA
                     HAAAYVLMAVRIAYFKVHHALLYYAAYFTVRADDFDIDTMIKGSTAIRAVMEDINAKGL
                     DASPKEKNLLTVLELALEMCERGYSFQKVDLYRSSATEFIIDGNSLIPPFNSIPGLGTN
                     AALNIVKAREEGEFLSKEDLQKRGKVSKTILEYLDRHGCLESLPDQNQLSLF"
     CDS             9740..9919
                     /locus_tag="ctg7_870"
                     /transl_table=11
                     /translation="MEKDIFDLDLKIQTSKSNVEPNSIRLTFGCSGGVASKALCSRAMC
                     DGIVITKNYGYCDA"
     CDS             10001..12943
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RRE-containing: Lanthipeptide_LanB_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lant_dehydr_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     794.3; E-value: 2.4e-240)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg7_871"
                     /sec_met_domain="Lant_dehydr_N (E-value: 2.4e-150,
                     bitscore: 497.4, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lanthipeptide_LanB_RRE (E-value: 8.1e-08,
                     bitscore: 28.6, seeds: 20, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 3.8e-29, bitscore:
                     97.9, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSLKKDSLKNIEQKWFSLDSFFIRTPTLSLTFLENYLHKMINGK
                     ESYSNWVKDLINNPIFMEAIYIASPSLYENLKYWKNITDKKRKEQIAISLNNYLLRMTS
                     RTTPFGLFSSVTVGRFENETSINIDPLVHNIKKCNPDMNWLYKLIKKLEKENSIFLELN
                     VKFNNLVEKVGNRYFLSYNSKIDSARQNNITNDISSIIVSPPIEIIEKLTQEPLKIKNI
                     LRYLKKEYSSVTSEKILSLIHNLVDQDYLITDLRPSLLEKSPFNYVINKIKSIEKQDLQ
                     YILQELLSIQAKINYYETLPIGEGLNEVNEIEKLMSNLVVSDIYLQVNLSLNNKSEIKL
                     SNNVKKDLIELTECLEYFSITNNKPRHLKNYLNEFIDKYGEHREVELLELLNNDIGLGS
                     PASYKNPTSTREFIYKSNQKLENYLLRKLLNSIKENEQEIEITLEELKHLNKEKNISGQ
                     NNFVKSFEIFGNIVADNIDSFNKGKYTIFLNSENPVSNFAGKAAGRFTDLLKDKTNVKQ
                     FYDQQTICEHYINAEMSYTPNNGKIANIMMVDNFSDYEINLNNFCSEENETIPIEDIVV
                     GVEEDLFYFKSKNLNKRINISVNSLVNMDITPNVFRFIQEASLFNDQYLTGFNWGRLIE
                     SEFLPRVKFKKTILSPAMWNFNLSDHITEKPNYDEWLKIFKRWAKKWSIPKSVYLVEGD
                     EKLFLNLDVHLHLKILYKKIQKMKIIRLIESEINLSKSWAQDRNKNKYNIEFIFPLIQN
                     KNNNSIGKTKKNKPIIYTNSILTKKQIGSDWLYFKLYFNSFRDEEIIADHIPSFLNQLI
                     NNNQLINKYFYVRYLDDKPHIRLRIQGDPNILLSTVLIKMKDWTSNLIEGGLINKIELS
                     CYEREIERYGGPDFIDICETLFYYDSICVSELFNFLSYTTNELFDKETIAVLSVIFYLE
                     EIGFDYNQQLNLFERILENNKFPKEFRLKKDYLVFLCNSNLNWSNLRKSED"
ORIGIN
        1 ggctgagtaa ttttatgcta tggcaggttg cctacagtga atttgtcttt actgacgtct
       61 tgtggcctga ctttaaagaa gatcacttct tgcaggcgtt aggagagttt cagcagagag
      121 gccggaggtt tggcggaatt tagaggatgg tggacatgaa acaaagaatt ttgacaggtg
      181 ttctggcagc aattgtattt ttatttttgg ttattgtcgg ggaattgccg ttcaccatat
      241 taatttatgc tatgggcagt gtggcgcttt ttgaactttt acggatgaaa aagctgaagc
      301 tggtttcact gccgggtttg atcggtcttt tattgttgtg gatgttctta ttgccaagcc
      361 agtattcgtt ttttgaagcg gacggaattt ccaaaatgga aatcgcttta tttgcggtac
      421 tgctattgct gacttacaca gtgttggtca agaacacctt tacttttgat gaagtcgggt
      481 ttattacgct tgcagcaatt tacatcggaa tgtgttttca ttattttatc gaaatcagaa
      541 atcttgacca atacggatta acatacattt tttatgcgtg tgttgtcatt tggtccacgg
      601 attccggtgc ctattttgtc ggtaaatcgc ttgggaagcg gaaactgtgg cctgaaatca
      661 gtccgaataa aacagtggaa gggtttgcag gcggaattgt catcgcactt gtattggcga
      721 cgatttttca gcttgttgca caacttccga tcccgtatat ctatctgctg ttgatcacgc
      781 tgtttttgtc tgttttcgga caacttggag atttagtgga atccgccttg aaaagacatt
      841 acgatgtaaa ggattctggg aatattcttc ctgggcatgg cggtatatta gaccgttttg
      901 acagtttctt gtttgtcatg cctttcttgt actttctgct tgcccttttt tcataaaaaa
      961 gtctaatatg aatatgagac tgatcatgca gcaataagaa taggagtagt ggcaactttg
     1021 aaaaatattt gtcttttagg agcaacagga tcaatcggcg aacagactct tgatgtactg
     1081 cgtgcacatc aagatcaatt tcagctggta tctatgtcgt ttggcagaaa tattgataag
     1141 gccgttccaa tgattgaggt ctttcagccg aagtttgtct ctgtcggtga tctggataca
     1201 tatcataaat taaaacaaat gtctttttct tttgaatgcc aaatcgggct gggagaagaa
     1261 ggactgatag aagcagcagt gatggaggag gttgacattg ttgtcaacgc tttgcttgga
     1321 agcgtcggtc ttatcccgac gttaaaggca attgaacaga aaaaaacaat tgcgcttgca
     1381 aataaggaaa ctcttgtcac tgcagggcat atagtaaaag aacatgctaa gaaatatgat
     1441 gttccgctgc tgcctgttga cagtgagcat tcagccattt ttcaagctct tcaaggcgaa
     1501 caggctaaaa acattgaacg cctcatcatt acggcatccg gcggaagttt tcgggacaag
     1561 acgcgggagg agctcgaatc agtaacggtt gaagatgcat taaaacatcc aaactggtca
     1621 atgggtgcaa aaattacaat tgattcggct acaatgatga ataagggatt agaggtaatc
     1681 gaggcacact ggcttttcga tataccttat gaacaaattg atgtggtttt acataaggag
     1741 agcatcatcc attcaatggt cgagttccat gataaaagtg tgatcgcaca gctcggaact
     1801 ccggatatga gagtccccat tcaatatgcg ctcacttatc ctgaccgatt gccattacca
     1861 gatgcgaaaa ggcttgaatt atgggaaatc ggcagccttc attttgagaa agctgatttt
     1921 gacaggttcc gatgcttaca atttgctttt gaatcaggta aaataggagg aacaatgccg
     1981 acagtgctaa atgcggcaaa cgaagtagct gtcgctgcct ttttagctgg caagataccg
     2041 tttttggcta ttgaagactg tatcgaaaag gcactaaccc gccatcaatt actgaaaaaa
     2101 ccgagcctgg cggacattca agaagtggac aaagataccc ggggatacgt caattcaata
     2161 ctcacataag gtggtatgtt cgtgaataca gttatagcgt ttatcattat tttcggaacg
     2221 ctcgttttct tccatgaact gggccattta ttgctagccc aaagagcggg aattctctgc
     2281 cgtgaatttg cgatcggctt cggtccaaag attttttctt tcaaaaaaaa tgaaacagtt
     2341 tatacgatca ggctgcttcc ggtcggcgga tttgttcgta tggccggcga agatccggaa
     2401 atgattgagg tgaaacccgg atacacggtc gggcttctgt ttaataagga agatcaagtt
     2461 gagaaagtca tcatcaatca aaaggaaaaa tatccggatg ctttagtcat tgaagtggaa
     2521 acagcggatc tagagcatga catgaagatc accggttatg aacaggggaa agaggacgaa
     2581 ctttccagct ttactgtcag cgaaacatcc ttttttattg tagacggaga agaagtgcag
     2641 attgcgccgt ataatcgcca atttggttcc aaacctgtgt ggcagcggat taaagcaatt
     2701 gctgcagggc cgattatgaa ctttatttta gcttacgtca ttttagtgat gcttgggctg
     2761 attcaaggcg taccgtcaaa tgaacctatg ctcgggcagc tgacagacaa tggacgggca
     2821 gctgaagcag ggctaaaaga aggggattat atccaaagca ttaacggaga gaaaatgagg
     2881 tcttggactg acattgtctc cgctgtaaaa gaaaacccgg agaaagaaat ggacgttgca
     2941 gtaaaaagag ctaacaaaac gcttcatatt tcggtgactc cggaagctgt taaagatgag
     3001 aacaaaaaaa caatcggccg ctttggttct tacgcgccaa ctgagaaagg cgttctctca
     3061 gcagttgctt acggcgcgac atcaacagtt gacattggca atcaaatctt agaaacgttt
     3121 ggtaatttag taacaggaca atttaaaata aatatgttgg cgggaccagt tggtatttat
     3181 gatatgacag accaagtggc gaaaaccggg ttagttaatt tggttcgttt cgctgcgttt
     3241 ttaagcatta atcttgggat tgtcaacctg cttccgattc cggcacttga cggaggaaga
     3301 ctgttgtttc tatttattga agcgattcgg ggcaaaccga ttaacaggga aaaagaagca
     3361 tttgttgtgt ttatcggagt agctttctta atgcttctta tgctggttgt cacatggaac
     3421 gatatccagc ggctgttttt gtaaacgaaa agtaaatcaa tcagaggtgc gaagaaatga
     3481 gacaaagctt gacgcttatt cctacgctcc gtgaagttcc agctgatgcc gaagcaaaaa
     3541 gtcatcagct tcttctgaga gcaggattta tcagacagaa tacgagcggg gtatacagct
     3601 atatgcctct tgcgtataag gtgattcaaa acattcagca gattgttcga gaagaaatgg
     3661 agaaaattga tgccgtagaa atgctcatgc ctgcgttgca gcaggcagag acatggcagg
     3721 aatcaggcag atggtatacg tatggtcccg aactgatgag actaaaagac cgtcatggcc
     3781 gtgaatttgc tttaggggca acgcatgaag aggttatcac ttcgcttgtt cgcgatgagg
     3841 ttaaatctta taagcgtctc cctctgactc tttatcaaat tcagtctaag ttcagagatg
     3901 aaaaacgtcc tcgcttcggt ttgttaagag gccgcgaatt tattatgaag gatgcgtact
     3961 ctttccatgc atctgcagag agcctggatg aaacgtatca aaaaatgtac gaggcctatt
     4021 ctaatatttt tgcccgctgc ggcattaatg taagacctgt tatcgctgat tcaggcgcaa
     4081 tgggaggaaa ggatacgcac gaatttatgg cactttctgc gatcggagag gatacgattg
     4141 cgtattctga tgaatcacag tacgcggcta atatcgagat ggctgaagtt cttcaccagg
     4201 aagttccttc agatgaagag cctaaagctc tagagaaggt tcatacgcct aacgtgaaaa
     4261 caatcgaaga actgactgcg ttcttacagg tttcggctga agcgtgcatt aagtcagtat
     4321 tgtttaaagc tgatgaccgt tttgtcttag tgcttgtaag aggggatcat gaagttaacg
     4381 atattaaagt gaaaaacttg cttcatgcag aagttgtaga gcttgctaca catgaagagg
     4441 tcattcagca gctcggaaca gagccaggtt ttgtaggccc tgttggtatt catcaggatg
     4501 tggaagtata tgccgatcaa gctgtgaaag caatggttaa tgctgttgcc ggggcaaatg
     4561 aaggagatca tcattataaa aatgtcaatg tgaatcgtga cgcgcaaatt aaagaatttg
     4621 ctgatcttcg ttttattaaa gaaggtgatc cttcaccaga cggcaaggga acgatccgtt
     4681 ttgctgaggg aatcgaagtc ggacaagtct ttaagctcgg aacacgctat tcagaagcga
     4741 tgaatgcgac atatttagat gaaaacggac gcgcgcagcc aatgctgatg ggctgttacg
     4801 gaatcggtgt gtcaagaacg ctttctgcta ttgctgaaca gcatcacgac gaaaaaggat
     4861 taatatggcc aaaaagcgtt gccccgtacg atcttcatat tcttgcattg aacatgaaaa
     4921 acgatgggca aagagagctt gctgaaaagc tgtatgccga tttaaaagcg gaaggctatg
     4981 aagtgctcta tgacgaccgt gctgagcgtg ccggtgtaaa attcgctgat tcagatctaa
     5041 tcggccttcc aatccgcatc actgtcggaa aacgggctga cgaaggaatc gtcgaagtga
     5101 aaattcgtca aactggtgag tcaactgaga tttcagtaga cgaattatct gcgtttatca
     5161 gcaagcagta atcaccataa cgatttatca aaaaacatgt taaaatagaa ataatagaag
     5221 gtacctcatt gcctgaggta ccttcactta tgatgttttt agggagggat actgtcttaa
     5281 tggaacagtt atcagtaaac agaaggcagt ttcaaattct tctgcagcag attaatatga
     5341 cagatgatac cttcatgaca tactttgaac atggcgagat taaaaagctg acaattcaca
     5401 aagcttctaa atcttggcat tttcattttc aatttaaatc tttgctgcct tttcaaatat
     5461 atgacacatt aacaacgagg ctgacgcaat cgtttgccca catagcaaaa gtgacatctt
     5521 caattgaagt tcaggatgcc gaggtcagtg aaagtatcgt tcaagactac tggtcacgct
     5581 gcattgaaga actgcagggc atttcgccgc cgatcatcag tcttttaaac cagcaaaaac
     5641 cgaagctgaa gggcaataaa ctgattgtca aaaccaaaac ggatacagaa gcggctgcgc
     5701 taaagaacaa atacagttcc atgatacaag caggctaccg tcaatttggc tttccagatc
     5761 ttcagcttga tgctgaaata tttgtatccg agcaggaagt tcaaaagttt cgggagcaaa
     5821 agcttgcaga agaccaagag cgggctatgc aggccttgat tgaaatggag aagaaagata
     5881 aagaaagtga tgaagaccaa gcaccatctg gtcctcttgt tatcggttat caaattaaag
     5941 ataacgagga aattcggaca cttgacagca tcatggacga agaacggaga attacggtcc
     6001 aaggttatgt gtttgatgtg gagacgcgcg agctgaagag cgggcgcacg ctgtgtatct
     6061 tcaaaattac agactataca aatagtattt tgatcaaaat gtttgcacgt gaaaaagaag
     6121 atgcggcact gatgaagtct ctgaaaaaag gaatgtgggt aaaagcacgc ggaagcattc
     6181 aaaatgatac atttgtcaga gaccttgtca tgatcgcaaa tgacgtaaac gaaataaaag
     6241 caaaaacccg tgaagattca gcacctgaag gagaaaaaag agtggaattg catcttcatt
     6301 ccccaatgag ccaaatggat gctgttacgg gtattggaaa gcttgtcgaa caggcgaaaa
     6361 aatgggggca tgaggccatc gctttgactg accatgctgt cgttcaatcc ttccctgatg
     6421 cgtattctgc ggccaaaaag catggaatta aaatgattta cgggatggaa gcgaatctcg
     6481 tggatgatgg cgtgccaatt gcttataatg ccgcacatcg tctgctcgaa gaagaaacat
     6541 atgttgtttt tgacgttgag acgacaggat tgtctgctgt atacgatacc attattgagc
     6601 tggctgcagt aaaagtaaaa ggcggagaaa ttattgataa atttgaggcg tttgcgaacc
     6661 cgcatcgtcc gctttccgcc acaatcatag agctgacagg gatcactgat gatatgctac
     6721 aagacgctcc ggatgtcgta gatgtaataa gagatttcag agaatggatt ggcgatgata
     6781 tccttgtcgc tcataatgca agctttgata tgggattctt aaatgtagcc tataaaaagc
     6841 ttcttgaagt cgataaagct aaaaacccag tcattgacac gctagaacta ggacgttttc
     6901 tctatccgga atttaagaac caccggctga acacactttg taaaaagttt gatatcgaac
     6961 tcacacagca tcaccgtgcg atctatgata ctgaggcaac cgcttatttg cttctgaaaa
     7021 tgctgaaaga cgcggctgaa aaaggtattc agtaccatga tgagttgaat gaaaatatgg
     7081 gtcagtccaa tgcttatcaa agatcaagac cgtatcatgc aacattactt gccgtgaaca
     7141 gcacgggact taaaaattta tttaagcttg tgtcactttc tcatattcat tatttttaca
     7201 gagtgccgcg tattccgaga tctcagcttg agaaatacag ggaagggctg ctgatcggtt
     7261 ctgcctgtga caggggagag gtttttgagg gaatgatgca aaaatcgcct gaagaggtgg
     7321 aagatatcgc gtcattctat gattaccttg aggttcagcc gcctgaagtg tatcgtcact
     7381 tgctggagct tgaactggtc cgtgatgaaa aagcgctgaa agaaattatt gcgaatatca
     7441 cgaagctggg ggaaaagctt aataaaccgg ttgttgctac gggaaatgtt cattacttga
     7501 atgatgagga taaaatctac agaaagattt taatatcctc acaaggcggg gcaaatccgc
     7561 tgaataggca tgaactgccg aaagtgcatt tcagaacgac agacgaaatg cttgaagctt
     7621 tttctttctt aggtgaaaaa aaagcgaagg agatcgtagt caccaatacc caaaaggttg
     7681 cttctttagt tgatgacatc aagccgatta aagatgattt atatacgccg aaaatcgaag
     7741 gcgctgatga agagatcaga gaaatgagct atcagcgtgc aagaagcatt tacggggaag
     7801 agctgcctga aattgtcgaa gcgcggattg aaaaagagtt aaagagtatt attggccacg
     7861 gatttgctgt tatttacttg atctctcaca aacttgtaaa acgttcacta gatgacgggt
     7921 atctcgttgg ttcccgtggt tccgtaggat cttcattagt tgcgacactt actgagatta
     7981 ctgaggtaaa cccgctgccg ccgcactatg tttgtcctga gtgccagcat tctgagttct
     8041 ttaatgacgg ttctgtcggt tccggttttg acctgcctga caagacatgc cctcattgcg
     8101 gaacgccttt gaaaaaagac ggccatgata ttccatttga aacgttctta ggatttaaag
     8161 gggacaaagt acctgatatc gatttgaact tctcagggga atatcagccg caagcacaca
     8221 attacacaaa agtattgttc ggggaagaca atgtatatcg tgcgggaaca ataggcacgg
     8281 tggcagaaaa aacagcctac ggttatgtaa aaggctatgc cggagacaac aatcttcata
     8341 tgcgcggtgc cgaaatagat cggctcgtac agggatgcac aggtgtaaaa cgtacaactg
     8401 gacaacaccc tggcggtatt atcgtagttc cggattatat ggatatttat gatttttcac
     8461 cgatccagtt cccggcagat gccacaggtt cagagtggaa aacgactcat tttgatttcc
     8521 actccatcca tgacaacctg ttaaaacttg atattctcgg acacgatgac ccgactgtta
     8581 ttcggatgct tcaagactta agcggaatag atccgaaaac aattccgacg gatgatcctg
     8641 aagtgatgaa gatcttccag ggaaccgaat cactcggtgt gactgaagaa cagattggct
     8701 gtaaaacggg cactcttgga attcctgaat tcggaacccg atttgtccgg cagatgcttg
     8761 aagatacaaa gccgaccact ttttctgagc tcgttcagat ttcaggcttg tctcacggaa
     8821 ctgatgtatg gcttggcaat gcacaggagc tcatccacaa taatatttgt gagctgagtg
     8881 aggttatcgg ctgccgtgat gacattatgg tttatttaat ctatcaaggc cttgaaccgt
     8941 cccttgcctt taaaatcatg gaattcgtgc gtaaaggaaa aggattaacg cctgaatggg
     9001 aagaagaaat gaaaaataac aatgtcccag actggtatat tgattcttgt aaaaagatta
     9061 aatacatgtt cccgaaagcc cacgccgcgg catatgtctt aatggcagtc cgcattgctt
     9121 actttaaagt gcatcatgct cttttgtatt atgcggctta ttttaccgtt cgtgcagatg
     9181 actttgatat tgatacaatg atcaagggct ctacagcaat cagagcggta atggaggata
     9241 taaacgctaa aggactcgat gcttcaccga aggaaaagaa ccttctgact gttttagaat
     9301 tagcgcttga gatgtgtgag agaggctatt cattccaaaa agtcgattta tatcgctcca
     9361 gcgctacaga gtttattatt gacggcaaca gtcttattcc gccgtttaac tctattccag
     9421 ggttagggac gaacgctgct ttgaacattg taaaagctcg cgaagaaggc gaattcctct
     9481 caaaagaaga tttgcaaaag agagggaaag tatcaaaaac gattttagag tacttagatc
     9541 gccatggctg tctggagtca ctgcctgatc aaaatcaatt gtcactgttt taaaataaaa
     9601 aagacacagt tttcttaatt gtgtcttttt ctgttttgaa aataattaaa atataaacaa
     9661 ttaagtcgaa tgttaaagta taatattgac atataaacaa aatatatgtt acatttctat
     9721 taaaagggag gtgattggtt tggaaaagga tatttttgat ttagatttga aaattcaaac
     9781 gagcaaatcg aatgtagaac ctaatagtat tcgacttacc tttggttgca gtggtggtgt
     9841 cgcttcaaaa gctctctgtt ctcgggcaat gtgtgatggt atcgttatta ctaaaaacta
     9901 tgggtattgt gatgcttaat attttgggtg aagatagtat tatcttcacc tctttggtaa
     9961 gttgtttaat taaatttgtt ataaagagag tgttgtttat atgaaatcac taaagaaaga
    10021 tagtttaaag aatatagagc agaaatggtt ctctttagat agtttcttta ttagaactcc
    10081 tactttatct ctaacctttc ttgaaaatta tttacataaa atgataaatg gaaaagaaag
    10141 ttactctaac tgggtgaaag atttaattaa taatccaatt tttatggaag ctatttatat
    10201 tgccagtcct tcattatatg agaatttaaa atattggaaa aatataacgg acaaaaaaag
    10261 gaaagagcaa atagcaatat cattaaataa ttatttattg cggatgacct ctagaacaac
    10321 tccttttggg cttttctcca gtgttactgt tggaagattc gagaatgaaa cctcaattaa
    10381 tatagatcct cttgtacata atattaagaa gtgcaaccca gatatgaatt ggttatataa
    10441 gttgataaaa aaattagaaa aagaaaattc gattttttta gagcttaatg taaaattcaa
    10501 caacttagtt gagaaagtag ggaaccgtta ttttctttcc tataattcaa aaattgattc
    10561 tgcacgtcaa aataacataa caaatgacat aagctcaatc attgttagtc ctcctattga
    10621 aattatagag aagttaacac aagaacctct taaaataaaa aatatattaa ggtatttaaa
    10681 aaaagagtat tcctcagtaa ctagcgagaa aatattatct ttaatacaca atttagtaga
    10741 tcaagattac ttaattacag acttaagacc atctctgttg gagaaatcgc cgtttaatta
    10801 tgtgatcaat aaaattaaaa gtattgaaaa acaagattta caatatatcc ttcaggagtt
    10861 attatcaata caagctaaaa taaattatta tgaaaccttg ccaattggag aaggcttaaa
    10921 tgaagtcaac gagatcgaaa aactaatgag caatcttgtt gttagcgata tttacttaca
    10981 agttaatttg agtttaaata ataaaagtga gattaaatta agtaataatg taaaaaaaga
    11041 tttaatagaa ctgacagagt gtttagagta cttttctata acaaataata aacctcgaca
    11101 tctaaaaaac tatctaaatg aatttataga taagtatgga gagcatcgcg aggttgaatt
    11161 attagaatta ttaaataatg atatcggatt aggatctcca gcaagttata aaaatcctac
    11221 gagtactaga gagtttatct ataagagtaa tcaaaagttg gaaaactatt tgttaagaaa
    11281 gttacttaat tctataaaag aaaatgagca agaaattgaa attacattgg aagaactaaa
    11341 acatttaaat aaagaaaaaa atataagtgg ccaaaataat ttcgttaaat cgtttgaaat
    11401 attcggaaat attgtagctg ataatattga ttcctttaat aaaggaaagt atacaatatt
    11461 ccttaactct gaaaacccag tttctaactt tgcaggaaaa gccgcgggta gatttactga
    11521 tcttttaaaa gataaaacta atgtaaaaca attctatgac caacaaacaa tttgtgagca
    11581 ttatattaat gccgaaatga gttacacccc taataatggt aaaatagcca atattatgat
    11641 ggtagataat ttttccgact atgaaattaa ccttaacaac ttttgttctg aggaaaatga
    11701 aactattcca attgaggata tagttgtcgg cgtagaagag gatttatttt attttaaatc
    11761 caaaaactta aataagagaa ttaatattag cgtaaatagt ctagttaata tggatataac
    11821 tccaaatgta tttagattta tacaagaagc ttcattattt aatgatcaat atcttacagg
    11881 atttaattgg ggaagactaa tagaaagtga atttttacca agagttaaat tcaaaaaaac
    11941 aatattatcc cctgcaatgt ggaattttaa tttaagtgat catattacgg aaaaacctaa
    12001 ttatgatgaa tggttaaaaa tttttaaaag atgggcaaaa aaatggagta ttcctaaaag
    12061 tgtatattta gttgaaggtg atgaaaaatt atttttaaat ctagacgttc atcttcactt
    12121 gaaaatactg tataaaaaaa tccaaaaaat gaagattatt agattaatcg aaagtgaaat
    12181 taatttgtca aagtcatggg cacaagatag gaataaaaat aaatataaca tagagtttat
    12241 ttttcctctc atacaaaata aaaataataa tagtataggc aaaactaaaa agaataaacc
    12301 cattatttat actaatagta ttcttacaaa aaaacaaata ggcagtgatt ggttgtattt
    12361 caaattgtac tttaattcat ttagagatga agaaataatt gctgaccata ttccgtcttt
    12421 tttaaatcaa ttaattaata ataatcaatt aattaataaa tatttttatg tgcgttattt
    12481 agatgataaa ccgcatataa gattacgaat acagggagac cccaacattc ttttgtcgac
    12541 tgtattaata aaaatgaaag actggacatc aaatctaatt gaaggaggtt taattaataa
    12601 aatcgaatta tcttgctatg aaagagaaat tgaacgatat ggaggacctg attttataga
    12661 tatttgtgag actttatttt attatgatag catctgtgtc tctgagctat tcaatttttt
    12721 atcgtatact actaatgagt tatttgataa agagacaatt gcagttctta gtgtcatttt
    12781 ctacttagaa gaaataggtt ttgattataa tcaacaactt aatctttttg aaagaatttt
    12841 agagaataat aaatttccta aggaatttag attaaagaaa gactatttag ttttcctatg
    12901 taactcaaat ctaaattgga gtaacctaag aaaaagcgaa gatgg
//
