## Wed Jul  3 12:43:55 2024
## emapper-2.1.12
## /d223NFS/m128030022/anaconda3/envs/eggnog/bin/emapper.py -i /d223NFS/m128030014/NGP/gene_list/prokka_results/GCA_024460175.1/GCA_024460175.1.faa --temp_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_024460175.1/2.eggNOGmapper --output_dir /d223NFS/m128030022/NGPs/NGPs_new/databases/NGPs_DB/NGPs_db/GCA_024460175.1/2.eggNOGmapper --output eggNOG_out --override --cpu 20 -m diamond --sensmode fast
##
#query	seed_ortholog	evalue	score	eggNOG_OGs	max_annot_lvl	COG_category	Description	Preferred_name	GOs	EC	KEGG_ko	KEGG_Pathway	KEGG_Module	KEGG_Reaction	KEGG_rclass	BRITE	KEGG_TC	CAZy	BiGG_Reaction	PFAMs
NFNHFNFO_00002	33035.JPJF01000016_gene3898	0.0	1070.0	COG1293@1|root,COG1293@2|Bacteria,1TQ8A@1239|Firmicutes,248RK@186801|Clostridia,3XZD2@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	FbpA	-	-	-	-	-	-	-	-	-	-	-	DUF814,FbpA
NFNHFNFO_00003	33035.JPJF01000016_gene3897	3.31e-187	524.0	COG1561@1|root,COG1561@2|Bacteria,1TQHJ@1239|Firmicutes,24824@186801|Clostridia,3XZFM@572511|Blautia	186801|Clostridia	S	Psort location	yicC	-	-	-	-	-	-	-	-	-	-	-	DUF1732,YicC_N
NFNHFNFO_00004	33035.JPJF01000016_gene3896	8.61e-54	169.0	COG2052@1|root,COG2052@2|Bacteria,1VA40@1239|Firmicutes,24MXV@186801|Clostridia,3Y0BZ@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF370)	NPD7_560	-	-	ko:K09777	-	-	-	-	ko00000	-	-	-	DUF370
NFNHFNFO_00005	33035.JPJF01000016_gene3895	4.14e-139	394.0	COG0194@1|root,COG0194@2|Bacteria,1TP0M@1239|Firmicutes,24HEX@186801|Clostridia,3XYVA@572511|Blautia	186801|Clostridia	F	Essential for recycling GMP and indirectly, cGMP	gmk	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
NFNHFNFO_00006	33035.JPJF01000016_gene3894	2.89e-44	144.0	COG1758@1|root,COG1758@2|Bacteria,1VF65@1239|Firmicutes,257WP@186801|Clostridia,3Y0N6@572511|Blautia	186801|Clostridia	K	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits	rpoZ	-	2.7.7.6	ko:K03060	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb6
NFNHFNFO_00007	33035.JPJF01000016_gene3893	4.5e-314	856.0	COG0621@1|root,COG0621@2|Bacteria,1TP2W@1239|Firmicutes,2487D@186801|Clostridia,3XYI9@572511|Blautia	186801|Clostridia	H	Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12	rimO	-	2.8.4.4	ko:K14441	-	-	R10652	RC00003,RC03217	ko00000,ko01000,ko03009	-	-	-	Radical_SAM,TRAM,UPF0004
NFNHFNFO_00008	33035.JPJF01000016_gene3892	8.59e-115	330.0	COG0558@1|root,COG0558@2|Bacteria,1V6PJ@1239|Firmicutes,24J7Y@186801|Clostridia,3XZV4@572511|Blautia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score	pgsA	-	2.7.8.41,2.7.8.5	ko:K00995,ko:K08744	ko00564,ko01100,map00564,map01100	-	R01801,R02030	RC00002,RC00017,RC02795	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
NFNHFNFO_00009	33035.JPJF01000016_gene3891	4.08e-289	791.0	COG1058@1|root,COG1546@1|root,COG1058@2|Bacteria,COG1546@2|Bacteria,1TQ1N@1239|Firmicutes,249WC@186801|Clostridia,3Y099@572511|Blautia	186801|Clostridia	S	Belongs to the CinA family	cinA	-	3.5.1.42	ko:K03742,ko:K03743	ko00760,map00760	-	R02322	RC00100	ko00000,ko00001,ko01000	-	-	-	CinA,MoCF_biosynth
NFNHFNFO_00010	33035.JPJF01000016_gene3890	1.1e-47	162.0	2EMJQ@1|root,32KAG@2|Bacteria,1URUU@1239|Firmicutes,259SC@186801|Clostridia,3Y0NU@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00011	33035.JPJF01000016_gene3888	2.04e-68	207.0	2BB22@1|root,324I6@2|Bacteria,1UQT3@1239|Firmicutes,258J6@186801|Clostridia,3Y0Q8@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00013	33035.JPJF01000016_gene3886	3.71e-19	81.3	2DSHC@1|root,33G4Q@2|Bacteria,1VMRV@1239|Firmicutes,25AFM@186801|Clostridia,3Y0T4@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score 8.82	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00014	33035.JPJF01000016_gene3885	0.0	1071.0	COG1404@1|root,COG1404@2|Bacteria,1TQE0@1239|Firmicutes,25B1A@186801|Clostridia,3XYTR@572511|Blautia	186801|Clostridia	O	COG COG1404 Subtilisin-like serine proteases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
NFNHFNFO_00015	33035.JPJF01000016_gene3884	4.31e-194	539.0	COG1404@1|root,COG1404@2|Bacteria,1TQRU@1239|Firmicutes,249H1@186801|Clostridia,3XYHC@572511|Blautia	186801|Clostridia	O	Psort location Extracellular, score	aprX	-	-	ko:K17734	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_S8
NFNHFNFO_00016	33035.JPJF01000016_gene3883	0.0	932.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2495J@186801|Clostridia,3XZMI@572511|Blautia	186801|Clostridia	E	COG COG0119 Isopropylmalate homocitrate citramalate synthases	-	GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0036440,GO:0046912,GO:0050450	-	-	-	-	-	-	-	-	-	iHN637.CLJU_RS03250	HMGL-like
NFNHFNFO_00017	33035.JPJF01000016_gene3882	8.38e-154	433.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24E6I@186801|Clostridia,3XZX2@572511|Blautia	186801|Clostridia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NFNHFNFO_00018	33035.JPJF01000016_gene3881	4.34e-281	769.0	COG0538@1|root,COG0538@2|Bacteria,1TSKB@1239|Firmicutes,247KX@186801|Clostridia,3XZ3V@572511|Blautia	186801|Clostridia	C	Belongs to the isocitrate and isopropylmalate dehydrogenases family	icd	-	1.1.1.42	ko:K00031	ko00020,ko00480,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,ko04146,map00020,map00480,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230,map04146	M00009,M00010,M00173,M00740	R00267,R00268,R01899	RC00001,RC00084,RC00114,RC00626,RC02801	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
NFNHFNFO_00019	33035.JPJF01000016_gene3879	3.23e-194	541.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,24941@186801|Clostridia,3XZG6@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,SRP54
NFNHFNFO_00020	33035.JPJF01000016_gene3878	1.23e-165	466.0	COG1277@1|root,COG1277@2|Bacteria,1V2P1@1239|Firmicutes,24BRH@186801|Clostridia,3Y0EK@572511|Blautia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
NFNHFNFO_00021	33035.JPJF01000016_gene3877	0.0	1112.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3XYWT@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
NFNHFNFO_00022	33035.JPJF01000016_gene3876	3.57e-151	425.0	COG2344@1|root,COG2344@2|Bacteria,1TSMR@1239|Firmicutes,247RQ@186801|Clostridia,3XZKT@572511|Blautia	186801|Clostridia	K	Modulates transcription in response to changes in cellular NADH NAD( ) redox state	rex	-	-	ko:K01926	-	-	-	-	ko00000,ko03000	-	-	-	CoA_binding,Put_DNA-bind_N
NFNHFNFO_00023	33035.JPJF01000016_gene3875	0.0	897.0	COG0062@1|root,COG0063@1|root,COG0062@2|Bacteria,COG0063@2|Bacteria,1TNZE@1239|Firmicutes,2480H@186801|Clostridia,3XZEG@572511|Blautia	186801|Clostridia	H	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration	nnrD	-	4.2.1.136,5.1.99.6	ko:K17758,ko:K17759	-	-	-	-	ko00000,ko01000	-	-	-	ACPS,Carb_kinase,YjeF_N
NFNHFNFO_00024	33035.JPJF01000016_gene3874	6.24e-256	704.0	COG0787@1|root,COG0787@2|Bacteria,1TNYY@1239|Firmicutes,2480T@186801|Clostridia,3XYKK@572511|Blautia	186801|Clostridia	M	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids	alr	-	5.1.1.1	ko:K01775	ko00473,ko01100,ko01502,map00473,map01100,map01502	-	R00401	RC00285	ko00000,ko00001,ko01000,ko01011	-	-	-	Ala_racemase_C,Ala_racemase_N
NFNHFNFO_00025	33035.JPJF01000016_gene3873	1.17e-75	226.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24JE1@186801|Clostridia,3Y03Z@572511|Blautia	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	ndoA	-	-	ko:K07171	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PemK_toxin
NFNHFNFO_00026	33035.JPJF01000016_gene3872	1.44e-233	642.0	COG0407@1|root,COG0407@2|Bacteria,1TNZU@1239|Firmicutes,24A05@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_00027	33035.JPJF01000016_gene3869	1.35e-296	813.0	COG1253@1|root,COG1253@2|Bacteria,1U77R@1239|Firmicutes,25CBE@186801|Clostridia,3XZ2E@572511|Blautia	186801|Clostridia	S	Transporter associated domain	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
NFNHFNFO_00028	33035.JPJF01000016_gene3868	3.66e-167	468.0	COG0217@1|root,COG0217@2|Bacteria,1TPP5@1239|Firmicutes,247NK@186801|Clostridia,3XYGX@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	yebC	-	-	-	-	-	-	-	-	-	-	-	Transcrip_reg
NFNHFNFO_00030	33035.JPJF01000016_gene3866	5.14e-152	429.0	COG0740@1|root,COG0740@2|Bacteria,1TPX2@1239|Firmicutes,249QX@186801|Clostridia,3XZDI@572511|Blautia	186801|Clostridia	OU	Psort location Cytoplasmic, score 8.87	tepA	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NFNHFNFO_00031	33035.JPJF01000016_gene3865	6.81e-194	540.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3XZWE@572511|Blautia	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP)	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
NFNHFNFO_00032	33035.JPJF01000016_gene3864	0.0	1490.0	COG1674@1|root,COG1674@2|Bacteria,1TPJR@1239|Firmicutes,247KM@186801|Clostridia,3XYXU@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	ftsK	-	-	ko:K03466	-	-	-	-	ko00000,ko03036	3.A.12	-	-	FtsK_4TM,FtsK_SpoIIIE,Ftsk_gamma
NFNHFNFO_00033	33035.JPJF01000016_gene3863	8.53e-198	556.0	COG0457@1|root,COG0457@2|Bacteria,1UZDE@1239|Firmicutes,24HQ4@186801|Clostridia,3Y29Z@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	CHB_HEX_C_1,TPR_19
NFNHFNFO_00034	33035.JPJF01000016_gene3862	1.74e-221	609.0	COG0543@1|root,COG0543@2|Bacteria,1TP6D@1239|Firmicutes,247YB@186801|Clostridia,3XZM3@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pyrK_1	-	1.18.1.2,1.19.1.1	ko:K00528,ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146,R10159	RC00065	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
NFNHFNFO_00035	33035.JPJF01000016_gene3861	0.0	913.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3XZ00@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	gltA	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	DHODB_Fe-S_bind,Fer4_20,Pyr_redox_2
NFNHFNFO_00036	33035.JPJF01000016_gene3860	1.39e-149	422.0	COG4912@1|root,COG4912@2|Bacteria,1TQII@1239|Firmicutes,248N8@186801|Clostridia,3XZY3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DNA_alkylation
NFNHFNFO_00037	33035.JPJF01000016_gene3859	4.28e-102	296.0	COG1576@1|root,COG1576@2|Bacteria,1V3JM@1239|Firmicutes,24HED@186801|Clostridia,3XZU3@572511|Blautia	186801|Clostridia	H	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA	rlmH	-	2.1.1.177	ko:K00783	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SPOUT_MTase
NFNHFNFO_00038	1232453.BAIF02000110_gene767	8.95e-120	357.0	2DMYR@1|root,32UEZ@2|Bacteria,1VCPN@1239|Firmicutes,24MHC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00039	33035.JPJF01000016_gene3855	1.55e-123	355.0	COG1011@1|root,COG1011@2|Bacteria,1TWM7@1239|Firmicutes,24HKY@186801|Clostridia,3Y0IN@572511|Blautia	186801|Clostridia	S	HAD-hyrolase-like	-	-	3.8.1.2	ko:K01560,ko:K07025	ko00361,ko00625,ko01100,ko01120,map00361,map00625,map01100,map01120	-	R05287	RC00697	ko00000,ko00001,ko01000	-	-	-	HAD_2
NFNHFNFO_00040	33035.JPJF01000016_gene3853	6.72e-43	141.0	28QBC@1|root,2ZCTY@2|Bacteria,1W2AX@1239|Firmicutes,24UH4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00041	33035.JPJF01000016_gene3852	1.62e-196	548.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,3XZIM@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
NFNHFNFO_00042	1007096.BAGW01000018_gene765	1.13e-40	137.0	2CTED@1|root,32ST9@2|Bacteria,1VD31@1239|Firmicutes,24Q04@186801|Clostridia,2N8GI@216572|Oscillospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00043	33035.JPJF01000016_gene3851	9.17e-98	286.0	28PZ1@1|root,2ZCII@2|Bacteria,1V2GX@1239|Firmicutes,24IE1@186801|Clostridia,3Y0MC@572511|Blautia	186801|Clostridia	S	Domain of unknown function, E. rectale Gene description (DUF3877)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3877
NFNHFNFO_00045	411470.RUMGNA_02509	4.64e-107	311.0	28P9U@1|root,2ZC37@2|Bacteria,1V32C@1239|Firmicutes,24FS7@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
NFNHFNFO_00046	357809.Cphy_0973	4.74e-177	501.0	COG1506@1|root,COG1506@2|Bacteria,1UISH@1239|Firmicutes,25EZ7@186801|Clostridia	186801|Clostridia	E	PFAM alpha beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
NFNHFNFO_00047	397287.C807_01491	7.36e-272	744.0	COG0517@1|root,COG0517@2|Bacteria,1TQ4J@1239|Firmicutes,24B68@186801|Clostridia,27KB9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative transposase	-	-	-	-	-	-	-	-	-	-	-	-	Y2_Tnp,Zn_Tnp_IS91
NFNHFNFO_00048	1042156.CXIVA_08070	1.62e-195	543.0	COG4974@1|root,COG4974@2|Bacteria,1V1BF@1239|Firmicutes,25C3Y@186801|Clostridia,36WP7@31979|Clostridiaceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
NFNHFNFO_00049	1280673.AUJJ01000025_gene1275	7.13e-98	296.0	COG0454@1|root,COG0456@2|Bacteria,1UXXB@1239|Firmicutes,248N5@186801|Clostridia,4BWJG@830|Butyrivibrio	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9
NFNHFNFO_00050	33035.JPJF01000016_gene3850	7.73e-51	167.0	28Z82@1|root,2ZM05@2|Bacteria,1W1JP@1239|Firmicutes,256QK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00051	33035.JPJF01000016_gene3849	6e-40	134.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,24QSQ@186801|Clostridia,3Y0N1@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
NFNHFNFO_00053	33035.JPJF01000016_gene3848	3.35e-133	379.0	COG2102@1|root,COG2102@2|Bacteria,1UAKZ@1239|Firmicutes,24C6P@186801|Clostridia	186801|Clostridia	S	Diphthamide synthase	-	-	-	-	-	-	-	-	-	-	-	-	Diphthami_syn_2
NFNHFNFO_00054	665950.HMPREF1025_01071	7.27e-286	781.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia,27IJX@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_5,Phage_integrase
NFNHFNFO_00055	1121115.AXVN01000105_gene594	3.87e-42	137.0	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24MZT@186801|Clostridia,3Y0CD@572511|Blautia	186801|Clostridia	L	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NFNHFNFO_00056	411460.RUMTOR_01830	1.74e-253	694.0	COG2946@1|root,COG2946@2|Bacteria,1UYFS@1239|Firmicutes,24FME@186801|Clostridia,3XYRH@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Rep_trans
NFNHFNFO_00057	1121115.AXVN01000105_gene592	1.76e-160	449.0	COG1476@1|root,COG1476@2|Bacteria,1VEKB@1239|Firmicutes,24DSY@186801|Clostridia,3Y29A@572511|Blautia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_00058	1121115.AXVN01000105_gene591	6.85e-113	323.0	COG3695@1|root,COG3695@2|Bacteria,1TPJI@1239|Firmicutes,249H6@186801|Clostridia,3XZ1A@572511|Blautia	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
NFNHFNFO_00059	500632.CLONEX_01687	1.06e-35	125.0	2DFMM@1|root,2ZSB3@2|Bacteria,1V5WG@1239|Firmicutes,24HBS@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00060	411461.DORFOR_02101	5.09e-238	654.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,27V1T@189330|Dorea	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	-	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
NFNHFNFO_00061	411460.RUMTOR_02695	1.26e-255	704.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	adh	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NFNHFNFO_00062	33035.JPJF01000016_gene3846	3.67e-80	238.0	COG3682@1|root,COG3682@2|Bacteria,1TUS9@1239|Firmicutes,25MRG@186801|Clostridia,3Y1RD@572511|Blautia	186801|Clostridia	K	Penicillinase repressor	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NFNHFNFO_00063	33035.JPJF01000016_gene3845	0.0	1108.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,24FVB@186801|Clostridia,3Y017@572511|Blautia	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	DUF4097,DUF4825,DUF4829,Peptidase_M56
NFNHFNFO_00064	33035.JPJF01000079_gene20	1.81e-186	521.0	COG1578@1|root,COG1578@2|Bacteria,1UURD@1239|Firmicutes,2492C@186801|Clostridia,3Y04B@572511|Blautia	186801|Clostridia	S	Protein of unknown function DUF89	-	-	-	ko:K09116	-	-	-	-	ko00000	-	-	-	DUF89
NFNHFNFO_00065	33035.JPJF01000079_gene19	1.07e-191	537.0	28IH1@1|root,2Z8IC@2|Bacteria,1TSE5@1239|Firmicutes,249UI@186801|Clostridia,3Y15Y@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF4003)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4003
NFNHFNFO_00066	33035.JPJF01000079_gene18	1.02e-125	359.0	28M7B@1|root,2ZAKT@2|Bacteria,1TQPQ@1239|Firmicutes,24B5V@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	MmcB-like
NFNHFNFO_00067	33035.JPJF01000079_gene17	1.14e-96	282.0	2E639@1|root,330SD@2|Bacteria,1VN8W@1239|Firmicutes,24WUI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00068	33035.JPJF01000079_gene16	2.38e-159	447.0	COG2176@1|root,COG2176@2|Bacteria,1V3E4@1239|Firmicutes,249X5@186801|Clostridia,3XZPP@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
NFNHFNFO_00069	33035.JPJF01000079_gene15	2.33e-167	469.0	COG0454@1|root,COG0456@2|Bacteria,1V8NW@1239|Firmicutes,25B2F@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_00070	33035.JPJF01000079_gene14	1.14e-137	390.0	COG1309@1|root,COG1309@2|Bacteria,1V3ZS@1239|Firmicutes,24H9U@186801|Clostridia,3XZV5@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_00071	33035.JPJF01000079_gene13	0.0	1266.0	COG1033@1|root,COG1033@2|Bacteria,1VSWA@1239|Firmicutes,247R6@186801|Clostridia,3XYKA@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07003	-	-	-	-	ko00000	-	-	-	MMPL
NFNHFNFO_00072	33035.JPJF01000079_gene12	1.5e-289	831.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,24A8K@186801|Clostridia,3XYKM@572511|Blautia	186801|Clostridia	S	Psort location Cellwall, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	-
NFNHFNFO_00073	33035.JPJF01000079_gene10	6.1e-126	359.0	COG5423@1|root,COG5423@2|Bacteria,1V5IN@1239|Firmicutes,24JW6@186801|Clostridia,3XZUH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NFNHFNFO_00074	33035.JPJF01000079_gene9	1.21e-58	181.0	2DVZX@1|root,33XWD@2|Bacteria,1U4E1@1239|Firmicutes,24VHN@186801|Clostridia,3Y0V7@572511|Blautia	186801|Clostridia	S	COG NOG13846 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	YabP
NFNHFNFO_00075	33035.JPJF01000012_gene2354	9.38e-205	573.0	COG0561@1|root,COG0561@2|Bacteria,1TR3N@1239|Firmicutes,24ACD@186801|Clostridia,3XYIC@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yqfD	-	-	ko:K06438	-	-	-	-	ko00000	-	-	-	YqfD
NFNHFNFO_00076	33035.JPJF01000012_gene2353	1.79e-75	226.0	COG4747@1|root,COG4747@2|Bacteria,1V8ZY@1239|Firmicutes,24NAM@186801|Clostridia,3Y0M9@572511|Blautia	186801|Clostridia	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00077	658086.HMPREF0994_01649	5.57e-92	274.0	COG1309@1|root,COG1309@2|Bacteria,1VH8G@1239|Firmicutes,24SA7@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NFNHFNFO_00078	658086.HMPREF0994_01650	1.76e-70	216.0	COG0778@1|root,COG0778@2|Bacteria,1VIF2@1239|Firmicutes,24GUE@186801|Clostridia	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NFNHFNFO_00079	658086.HMPREF0994_01651	2.79e-144	409.0	COG0778@1|root,COG0778@2|Bacteria,1V0I6@1239|Firmicutes,24ASS@186801|Clostridia	186801|Clostridia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	TM1586_NiRdase
NFNHFNFO_00080	411902.CLOBOL_06215	7.93e-140	410.0	COG1408@1|root,COG1408@2|Bacteria,1TS43@1239|Firmicutes,248XA@186801|Clostridia,220KZ@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NFNHFNFO_00081	478749.BRYFOR_08356	4.16e-113	331.0	COG3279@1|root,COG3279@2|Bacteria,1UYV2@1239|Firmicutes,24F5U@186801|Clostridia	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NFNHFNFO_00082	397288.C806_04287	1.08e-107	332.0	COG0642@1|root,COG0642@2|Bacteria	2|Bacteria	T	Histidine kinase	regB	-	2.7.13.3	ko:K07717,ko:K15011	ko02020,map02020	M00518,M00523	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HATPase_c_5,HisKA
NFNHFNFO_00083	1235790.C805_02635	1.41e-20	82.8	2ENRX@1|root,336BY@2|Bacteria,1VGQE@1239|Firmicutes,24U1U@186801|Clostridia,25YW2@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00084	1235790.C805_02634	6.73e-116	337.0	COG1131@1|root,COG1131@2|Bacteria,1TRG3@1239|Firmicutes,248K1@186801|Clostridia,25Y1J@186806|Eubacteriaceae	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_00085	1235790.C805_02633	8.4e-152	442.0	2BZD2@1|root,2Z88S@2|Bacteria,1UZZH@1239|Firmicutes,24F57@186801|Clostridia,25Y25@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00086	556261.HMPREF0240_02891	3.96e-150	432.0	COG1702@1|root,COG1702@2|Bacteria,1TP35@1239|Firmicutes,247ZJ@186801|Clostridia,36UI2@31979|Clostridiaceae	186801|Clostridia	T	PhoH-like protein	phoH	-	-	ko:K06217	-	-	-	-	ko00000	-	-	-	PhoH
NFNHFNFO_00087	33035.JPJF01000050_gene860	8.51e-105	303.0	COG0319@1|root,COG0319@2|Bacteria,1V6BU@1239|Firmicutes,24MQZ@186801|Clostridia,3Y06H@572511|Blautia	186801|Clostridia	S	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA	ybeY	-	3.5.4.5	ko:K01489,ko:K07042	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000,ko03009	-	-	-	UPF0054
NFNHFNFO_00088	33035.JPJF01000050_gene859	2.83e-267	735.0	COG1470@1|root,COG1470@2|Bacteria,1TRGE@1239|Firmicutes,24EHG@186801|Clostridia,3Y0I0@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3048) C-terminal domain	yerB	-	-	-	-	-	-	-	-	-	-	-	DUF3048,DUF3048_C
NFNHFNFO_00089	33035.JPJF01000050_gene858	9.22e-104	301.0	2EJV3@1|root,33DJR@2|Bacteria,1VKNR@1239|Firmicutes,25Q1A@186801|Clostridia,3Y0TC@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00090	33035.JPJF01000050_gene857	5.77e-183	511.0	COG0263@1|root,COG0263@2|Bacteria,1TPG6@1239|Firmicutes,2486P@186801|Clostridia,3XYIF@572511|Blautia	186801|Clostridia	H	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate	proB	-	2.7.2.11	ko:K00931	ko00330,ko00332,ko01100,ko01130,ko01230,map00330,map00332,map01100,map01130,map01230	M00015	R00239	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,PUA
NFNHFNFO_00091	33035.JPJF01000050_gene856	6.9e-41	135.0	COG4224@1|root,COG4224@2|Bacteria,1TUAX@1239|Firmicutes,24QS9@186801|Clostridia,3Y0QD@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ynzC	-	-	-	-	-	-	-	-	-	-	-	DUF896
NFNHFNFO_00092	33035.JPJF01000050_gene855	0.0	915.0	COG0621@1|root,COG0621@2|Bacteria,1TNYN@1239|Firmicutes,2482Y@186801|Clostridia,3XZB4@572511|Blautia	186801|Clostridia	H	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine	miaB	-	2.8.4.3	ko:K06168	-	-	R10645,R10646,R10647	RC00003,RC00980,RC03221,RC03222	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,TRAM,UPF0004
NFNHFNFO_00093	33035.JPJF01000050_gene854	0.0	1709.0	COG0249@1|root,COG0249@2|Bacteria,1TPRJ@1239|Firmicutes,248GI@186801|Clostridia,3XZGZ@572511|Blautia	186801|Clostridia	L	that it carries out the mismatch recognition step. This protein has a weak ATPase activity	mutS	-	-	ko:K03555	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_I,MutS_II,MutS_III,MutS_IV,MutS_V
NFNHFNFO_00094	33035.JPJF01000050_gene853	0.0	1035.0	COG0323@1|root,COG0323@2|Bacteria,1TPGK@1239|Firmicutes,24902@186801|Clostridia,3XYSA@572511|Blautia	186801|Clostridia	L	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex	mutL	-	-	ko:K03572	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	DNA_mis_repair,HATPase_c_3,MutL_C
NFNHFNFO_00095	33035.JPJF01000050_gene852	4.54e-215	596.0	COG0324@1|root,COG0324@2|Bacteria,1TPSC@1239|Firmicutes,248HB@186801|Clostridia,3XYZN@572511|Blautia	186801|Clostridia	H	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)	miaA	-	2.5.1.75	ko:K00791	ko00908,ko01100,ko01110,map00908,map01100,map01110	-	R01122	RC02820	ko00000,ko00001,ko01000,ko01006,ko03016	-	-	-	IPPT
NFNHFNFO_00096	33035.JPJF01000050_gene851	6.55e-309	842.0	COG4100@1|root,COG4100@2|Bacteria,1TQ88@1239|Firmicutes,247Y4@186801|Clostridia,3XZKZ@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	ynbB	-	-	-	-	-	-	-	-	-	-	-	Met_gamma_lyase
NFNHFNFO_00097	33035.JPJF01000050_gene850	1.51e-263	724.0	COG2081@1|root,COG2081@2|Bacteria,1TR7U@1239|Firmicutes,2497W@186801|Clostridia,3XZAP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
NFNHFNFO_00098	33035.JPJF01000050_gene849	0.0	872.0	COG2509@1|root,COG2509@2|Bacteria,1TPBW@1239|Firmicutes,247TR@186801|Clostridia,3XZI2@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	HI0933_like,NAD_binding_8,Pyr_redox_2
NFNHFNFO_00099	33035.JPJF01000050_gene848	2.13e-161	452.0	COG2003@1|root,COG2003@2|Bacteria,1TQ3K@1239|Firmicutes,2498Z@186801|Clostridia,3XZVG@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	radC	-	-	ko:K03630	-	-	-	-	ko00000	-	-	-	RadC
NFNHFNFO_00100	33035.JPJF01000050_gene847	2.13e-230	635.0	COG1077@1|root,COG1077@2|Bacteria,1TPVU@1239|Firmicutes,248CM@186801|Clostridia,3XZ2N@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
NFNHFNFO_00101	33035.JPJF01000050_gene846	7.27e-192	535.0	COG1792@1|root,COG1792@2|Bacteria,1TR1V@1239|Firmicutes,249M3@186801|Clostridia,3XYIE@572511|Blautia	186801|Clostridia	M	Involved in formation and maintenance of cell shape	mreC	-	-	ko:K03570	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreC
NFNHFNFO_00102	33035.JPJF01000050_gene845	3.39e-115	331.0	COG2891@1|root,COG2891@2|Bacteria,1V1EJ@1239|Firmicutes,24GF4@186801|Clostridia,3Y080@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score 9.99	mreD	-	-	ko:K03571	-	-	-	-	ko00000,ko03036	9.B.157.1	-	-	MreD
NFNHFNFO_00103	33035.JPJF01000050_gene844	0.0	1773.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,2480Z@186801|Clostridia,3XYNZ@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	mrdA	-	3.4.16.4	ko:K05515	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	PBP_dimer,Transpeptidase
NFNHFNFO_00104	33035.JPJF01000050_gene843	3.8e-179	499.0	COG2894@1|root,COG2894@2|Bacteria,1TP6P@1239|Firmicutes,249BB@186801|Clostridia,3XZ45@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	minD	-	-	ko:K03609	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31,CbiA
NFNHFNFO_00105	537007.BLAHAN_04751	1.89e-32	114.0	COG0851@1|root,COG0851@2|Bacteria,1UD8J@1239|Firmicutes,25HWB@186801|Clostridia,3Y0VC@572511|Blautia	186801|Clostridia	D	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell	minE	-	-	ko:K03608	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	MinE
NFNHFNFO_00106	33035.JPJF01000050_gene841	1.37e-236	654.0	COG0772@1|root,COG0772@2|Bacteria,1TPGH@1239|Firmicutes,247WS@186801|Clostridia,3XZJI@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	rodA	-	-	ko:K05837	-	-	-	-	ko00000,ko03036	-	-	-	FTSW_RODA_SPOVE
NFNHFNFO_00107	537007.BLAHAN_04753	6.55e-84	248.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3Y0B8@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
NFNHFNFO_00108	33035.JPJF01000050_gene839	1.9e-234	647.0	COG1686@1|root,COG1686@2|Bacteria,1TU06@1239|Firmicutes,25B23@186801|Clostridia,3XYXF@572511|Blautia	186801|Clostridia	M	COG COG1686 D-alanyl-D-alanine carboxypeptidase	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
NFNHFNFO_00109	33035.JPJF01000050_gene838	8.65e-87	256.0	COG0433@1|root,COG0433@2|Bacteria,1VF8X@1239|Firmicutes,24N9T@186801|Clostridia,3Y046@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00110	33035.JPJF01000050_gene837	6.73e-42	137.0	COG2155@1|root,COG2155@2|Bacteria,1TU48@1239|Firmicutes,259I6@186801|Clostridia,3Y0R3@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF378)	-	-	-	ko:K09779	-	-	-	-	ko00000	-	-	-	DUF378
NFNHFNFO_00111	33035.JPJF01000050_gene836	2.13e-301	828.0	2DBI9@1|root,2Z9F5@2|Bacteria,1UI10@1239|Firmicutes,25E9Z@186801|Clostridia,3XZB6@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00112	33035.JPJF01000050_gene835	1.86e-150	424.0	COG0325@1|root,COG0325@2|Bacteria,1TRDN@1239|Firmicutes,248R6@186801|Clostridia,3XYQJ@572511|Blautia	186801|Clostridia	S	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis	ylmE	-	-	ko:K06997	-	-	-	-	ko00000	-	-	-	Ala_racemase_N
NFNHFNFO_00113	33035.JPJF01000050_gene834	2.39e-96	285.0	COG1799@1|root,COG1799@2|Bacteria,1V5NF@1239|Firmicutes,25CNH@186801|Clostridia,3Y2EY@572511|Blautia	186801|Clostridia	D	Pfam:DUF552	sepF	-	-	ko:K09772	-	-	-	-	ko00000,ko03036	-	-	-	SepF
NFNHFNFO_00114	33035.JPJF01000050_gene833	1.53e-163	459.0	COG2302@1|root,COG2302@2|Bacteria,1U5V2@1239|Firmicutes,24GDV@186801|Clostridia,3XZX9@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	S4
NFNHFNFO_00115	33035.JPJF01000050_gene832	5e-253	695.0	COG0337@1|root,COG0337@2|Bacteria,1TPKZ@1239|Firmicutes,248H4@186801|Clostridia,3XYS7@572511|Blautia	186801|Clostridia	E	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)	aroB	-	2.7.1.71,4.2.3.4	ko:K01735,ko:K13829	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412,R03083	RC00002,RC00078,RC00847	ko00000,ko00001,ko00002,ko01000	-	-	-	DHQ_synthase
NFNHFNFO_00116	33035.JPJF01000050_gene831	6.58e-108	312.0	COG0597@1|root,COG0597@2|Bacteria,1VA9R@1239|Firmicutes,24QPP@186801|Clostridia,3Y0CB@572511|Blautia	186801|Clostridia	M	This protein specifically catalyzes the removal of signal peptides from prolipoproteins	lspA	-	3.4.23.36	ko:K03101	ko03060,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_A8
NFNHFNFO_00117	33035.JPJF01000050_gene830	6.14e-212	586.0	COG0564@1|root,COG0564@2|Bacteria,1TPCM@1239|Firmicutes,247Y2@186801|Clostridia,3XYRA@572511|Blautia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NFNHFNFO_00118	33035.JPJF01000050_gene829	1.11e-144	408.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249Z9@186801|Clostridia,3XYXM@572511|Blautia	186801|Clostridia	F	COG NOG14451 non supervised orthologous group	-	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin2
NFNHFNFO_00119	33035.JPJF01000050_gene828	7.16e-174	484.0	COG0037@1|root,COG0037@2|Bacteria,1TQ0Y@1239|Firmicutes,247RP@186801|Clostridia,3XZK0@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	ttcA2	-	-	-	-	-	-	-	-	-	-	-	ATP_bind_3
NFNHFNFO_00120	33035.JPJF01000050_gene827	2.74e-238	662.0	COG0628@1|root,COG0628@2|Bacteria,1TQ84@1239|Firmicutes,248FS@186801|Clostridia,3XZ5I@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NFNHFNFO_00121	33035.JPJF01000050_gene826	1.58e-95	279.0	COG1490@1|root,COG1490@2|Bacteria,1V6GH@1239|Firmicutes,24J90@186801|Clostridia,3Y036@572511|Blautia	186801|Clostridia	J	rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality	dtd	-	-	ko:K07560	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Tyr_Deacylase
NFNHFNFO_00122	33035.JPJF01000048_gene719	6.7e-100	320.0	COG5263@1|root,COG5263@2|Bacteria,1VH35@1239|Firmicutes,25KD3@186801|Clostridia,3Y04J@572511|Blautia	186801|Clostridia	D	Peptidase family M23	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Peptidase_M23
NFNHFNFO_00124	33035.JPJF01000048_gene718	4.56e-215	604.0	COG5002@1|root,COG5002@2|Bacteria,1URKI@1239|Firmicutes,248WK@186801|Clostridia,3XZE3@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_00125	33035.JPJF01000048_gene717	4.15e-134	382.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,25B20@186801|Clostridia	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00126	33035.JPJF01000048_gene716	0.0	1133.0	COG1653@1|root,COG1653@2|Bacteria,1V04I@1239|Firmicutes,247SU@186801|Clostridia,3XZJE@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_00127	33035.JPJF01000048_gene715	1.23e-149	425.0	COG1175@1|root,COG1175@2|Bacteria,1TQTC@1239|Firmicutes,24AQX@186801|Clostridia,3Y0K9@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_00128	33035.JPJF01000048_gene712	4.59e-164	472.0	2E1BR@1|root,32WRK@2|Bacteria,1V7RQ@1239|Firmicutes,24RD9@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00129	33035.JPJF01000048_gene711	2.44e-185	517.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,2496K@186801|Clostridia,3Y1G2@572511|Blautia	186801|Clostridia	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like,HTH_18
NFNHFNFO_00130	33035.JPJF01000048_gene710	1.11e-139	397.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,3Y2AY@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00131	33035.JPJF01000048_gene709	1.38e-85	264.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,3Y0BH@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_00132	33035.JPJF01000048_gene709	5.58e-99	297.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,3Y0BH@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_00133	33035.JPJF01000048_gene708	3.01e-145	410.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3XZQT@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_00134	33035.JPJF01000048_gene707	0.0	1235.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,3XZ2P@572511|Blautia	186801|Clostridia	MV	COG COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NFNHFNFO_00135	556261.HMPREF0240_00054	1.02e-77	238.0	COG1825@1|root,COG1825@2|Bacteria,1VA38@1239|Firmicutes,24N24@186801|Clostridia	186801|Clostridia	J	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance	ctc	-	-	ko:K02897	ko03010,map03010	M00178	-	-	ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L25p,Ribosomal_TL5_C
NFNHFNFO_00136	1121333.JMLH01000053_gene601	9.19e-89	263.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,3VR3M@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
NFNHFNFO_00137	33035.JPJF01000048_gene706	1.58e-275	759.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,24BRV@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_00138	33035.JPJF01000048_gene705	3.2e-189	527.0	COG0789@1|root,COG0789@2|Bacteria,1UZFF@1239|Firmicutes,24EUZ@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NFNHFNFO_00139	33035.JPJF01000048_gene704	0.0	2395.0	COG1201@1|root,COG1201@2|Bacteria,1UHYQ@1239|Firmicutes,25E79@186801|Clostridia	186801|Clostridia	L	DEAD DEAH box helicase	-	-	-	ko:K03724	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DEAD,DEAD_assoc,Helicase_C
NFNHFNFO_00140	33035.JPJF01000048_gene702	4.1e-87	256.0	COG5015@1|root,COG5015@2|Bacteria,1V4P5@1239|Firmicutes,25D0I@186801|Clostridia,3Y007@572511|Blautia	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
NFNHFNFO_00141	33035.JPJF01000048_gene701	1.83e-70	212.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24JJB@186801|Clostridia,3Y0QK@572511|Blautia	186801|Clostridia	K	HxlR-like helix-turn-helix	ydeP	-	-	-	-	-	-	-	-	-	-	-	HxlR
NFNHFNFO_00142	33035.JPJF01000048_gene699	2.3e-134	382.0	28HI8@1|root,2Z9QV@2|Bacteria,1UZZ2@1239|Firmicutes,24IH2@186801|Clostridia,3XZY4@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4317)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4317
NFNHFNFO_00143	553973.CLOHYLEM_05325	1.71e-148	440.0	COG2186@1|root,COG2186@2|Bacteria,1V12R@1239|Firmicutes,24QFG@186801|Clostridia,2206U@1506553|Lachnoclostridium	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
NFNHFNFO_00144	1504823.CCMM01000007_gene678	2.31e-26	124.0	COG3525@1|root,COG5263@1|root,COG3525@2|Bacteria,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	lacZ	-	3.2.1.23,3.2.1.52	ko:K01190,ko:K12373	ko00052,ko00511,ko00513,ko00520,ko00531,ko00600,ko00603,ko00604,ko01100,ko04142,map00052,map00511,map00513,map00520,map00531,map00600,map00603,map00604,map01100,map04142	M00079	R00022,R01105,R01678,R03355,R04783,R06004,R06114,R11316	RC00049,RC00452	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	CW_binding_1,F5_F8_type_C,Glug,Glyco_hydro_20,Peptidase_C39_2,SLH,YSIRK_signal
NFNHFNFO_00145	553973.CLOHYLEM_07366	0.0	1050.0	COG3590@1|root,COG3590@2|Bacteria,1TQTA@1239|Firmicutes,2482M@186801|Clostridia,21Z4C@1506553|Lachnoclostridium	186801|Clostridia	O	Peptidase family M13	pepO1	-	-	ko:K07386	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M13,Peptidase_M13_N
NFNHFNFO_00146	553973.CLOHYLEM_07365	2.48e-135	386.0	COG0745@1|root,COG0745@2|Bacteria,1TSRR@1239|Firmicutes,24AG3@186801|Clostridia,22036@1506553|Lachnoclostridium	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00147	553973.CLOHYLEM_07364	4.73e-151	441.0	COG0642@1|root,COG2205@2|Bacteria,1UHQC@1239|Firmicutes,2496X@186801|Clostridia,220BC@1506553|Lachnoclostridium	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NFNHFNFO_00148	1151292.QEW_2528	1.28e-103	303.0	COG1309@1|root,COG1309@2|Bacteria,1UH5U@1239|Firmicutes,249A2@186801|Clostridia,25U2U@186804|Peptostreptococcaceae	186801|Clostridia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
NFNHFNFO_00149	1151292.QEW_2527	1.44e-163	460.0	COG0500@1|root,COG2226@2|Bacteria,1V0UT@1239|Firmicutes,24B8S@186801|Clostridia,25TN8@186804|Peptostreptococcaceae	186801|Clostridia	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Methyltransf_11,Methyltransf_25
NFNHFNFO_00150	658086.HMPREF0994_05673	1.28e-170	481.0	COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,248CX@186801|Clostridia,27I9B@186928|unclassified Lachnospiraceae	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_00151	1226325.HMPREF1548_00583	5.35e-87	268.0	COG5434@1|root,COG5434@2|Bacteria,1TQXN@1239|Firmicutes,24APX@186801|Clostridia,36GYS@31979|Clostridiaceae	186801|Clostridia	M	Protein of unknown function (DUF3737)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3737
NFNHFNFO_00152	553973.CLOHYLEM_07113	4.38e-27	100.0	2DIP2@1|root,303S9@2|Bacteria,1TUIG@1239|Firmicutes,2584Q@186801|Clostridia,223F3@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00153	180332.JTGN01000004_gene2704	9.76e-84	253.0	COG0110@1|root,COG0110@2|Bacteria,1TSQQ@1239|Firmicutes,24B8G@186801|Clostridia	186801|Clostridia	S	Bacterial transferase hexapeptide repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
NFNHFNFO_00154	1235797.C816_01207	5.65e-113	340.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia,2N7B0@216572|Oscillospiraceae	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17,Fer4_9
NFNHFNFO_00155	658086.HMPREF0994_02807	1.32e-190	533.0	COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24GGX@186801|Clostridia,27P77@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NFNHFNFO_00156	658086.HMPREF0994_05081	4.77e-48	162.0	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NFNHFNFO_00158	97139.C824_03715	5.11e-120	344.0	COG1853@1|root,COG1853@2|Bacteria,1UYJS@1239|Firmicutes,24DWF@186801|Clostridia,36VGS@31979|Clostridiaceae	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NFNHFNFO_00159	665956.HMPREF1032_00732	4.3e-67	204.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24N2T@186801|Clostridia,3WQ13@541000|Ruminococcaceae	186801|Clostridia	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
NFNHFNFO_00160	1235792.C808_01197	3.16e-09	58.9	29A4Y@1|root,2ZX60@2|Bacteria,1W3FV@1239|Firmicutes,255KK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00161	1235792.C808_01188	1.32e-142	405.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,27KV6@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K02483	-	-	-	-	ko00000,ko02022	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00162	1232453.BAIF02000066_gene2127	4.02e-265	731.0	COG0642@1|root,COG2205@2|Bacteria,1UYAJ@1239|Firmicutes,24CIQ@186801|Clostridia,26AF2@186813|unclassified Clostridiales	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,HisKA
NFNHFNFO_00163	641112.ACOK01000003_gene3616	2.09e-193	542.0	COG0667@1|root,COG0667@2|Bacteria,1TQJC@1239|Firmicutes,25B10@186801|Clostridia,3WHPP@541000|Ruminococcaceae	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NFNHFNFO_00164	1507.HMPREF0262_02053	2.95e-14	69.7	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,36ICE@31979|Clostridiaceae	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
NFNHFNFO_00165	500632.CLONEX_00436	8.38e-52	169.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
NFNHFNFO_00166	332101.JIBU02000013_gene1357	1.71e-174	493.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia,36G6U@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_00167	411468.CLOSCI_03423	1.15e-138	394.0	COG0745@1|root,COG0745@2|Bacteria,1TT12@1239|Firmicutes,24AB1@186801|Clostridia,21XX7@1506553|Lachnoclostridium	186801|Clostridia	K	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00168	33035.JPJF01000048_gene686	3.43e-250	692.0	COG0038@1|root,COG0038@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,3Y07Q@572511|Blautia	186801|Clostridia	P	Voltage gated chloride channel	clcA	-	-	ko:K03281	-	-	-	-	ko00000	2.A.49	-	-	CBS,Voltage_CLC
NFNHFNFO_00169	1341157.RF007C_08860	3.07e-19	85.1	COG0535@1|root,COG0535@2|Bacteria,1V98T@1239|Firmicutes,24KUI@186801|Clostridia,3WRXR@541000|Ruminococcaceae	186801|Clostridia	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
NFNHFNFO_00170	1392491.JIAE01000001_gene1236	1.94e-43	149.0	COG0535@1|root,COG0535@2|Bacteria,1V98T@1239|Firmicutes,24KUI@186801|Clostridia,3WRXR@541000|Ruminococcaceae	186801|Clostridia	S	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Radical_SAM
NFNHFNFO_00171	33035.JPJF01000048_gene685	1.66e-248	683.0	COG4974@1|root,COG4974@2|Bacteria,1TPQB@1239|Firmicutes,25C3N@186801|Clostridia,3XYHX@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	xerS	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_1,Phage_integrase
NFNHFNFO_00172	33035.JPJF01000048_gene676	1.95e-36	125.0	2EJVN@1|root,3053J@2|Bacteria,1TUXT@1239|Firmicutes,25PYC@186801|Clostridia,3Y21F@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00173	33035.JPJF01000009_gene1568	2.3e-86	255.0	COG4954@1|root,COG4954@2|Bacteria,1V9Z7@1239|Firmicutes,24HGY@186801|Clostridia,3Y1U7@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF2000)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2000
NFNHFNFO_00174	33035.JPJF01000009_gene1567	1.43e-201	560.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,249RU@186801|Clostridia	186801|Clostridia	EG	metabolite transporter	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_00175	33035.JPJF01000009_gene1566	2.39e-203	563.0	COG2207@1|root,COG2207@2|Bacteria,1TPNZ@1239|Firmicutes,24A6R@186801|Clostridia,3Y15Z@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_00176	33035.JPJF01000009_gene1564	3.79e-244	675.0	COG0477@1|root,COG2814@2|Bacteria,1TRZB@1239|Firmicutes,24YGV@186801|Clostridia	186801|Clostridia	EGP	PFAM Major Facilitator Superfamily	-	-	-	ko:K08217	-	-	-	-	br01600,ko00000,ko01504,ko02000	2.A.1.21.1,2.A.1.21.22	-	-	MFS_1,MFS_3
NFNHFNFO_00177	33035.JPJF01000009_gene1562	4.24e-308	854.0	COG2602@1|root,COG4219@1|root,COG2602@2|Bacteria,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,249NV@186801|Clostridia,3XYWY@572511|Blautia	186801|Clostridia	KTV	Psort location CytoplasmicMembrane, score	blaR	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	Peptidase_M56,Transpeptidase
NFNHFNFO_00178	33035.JPJF01000009_gene1561	4.85e-75	225.0	COG3682@1|root,COG3682@2|Bacteria,1V7EY@1239|Firmicutes,24N11@186801|Clostridia,3Y08G@572511|Blautia	186801|Clostridia	K	beta-lactamase (penicillinase) repressor	blaI	-	-	ko:K02171	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01504,ko03000	-	-	-	Penicillinase_R
NFNHFNFO_00179	518637.EUBIFOR_01709	3.21e-37	128.0	2BNIM@1|root,32H78@2|Bacteria,1UHK4@1239|Firmicutes,3VR26@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NFNHFNFO_00180	537013.CLOSTMETH_02162	2.99e-204	567.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPIM@1239|Firmicutes,2480Y@186801|Clostridia	186801|Clostridia	K	transcription activator, effector binding	-	-	-	-	-	-	-	-	-	-	-	-	Cass2,HTH_18
NFNHFNFO_00181	411902.CLOBOL_02219	4e-91	267.0	2A1PZ@1|root,30PYD@2|Bacteria,1V4ZW@1239|Firmicutes,24KDH@186801|Clostridia,220SC@1506553|Lachnoclostridium	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
NFNHFNFO_00182	411902.CLOBOL_02218	3.84e-200	556.0	COG2378@1|root,COG2378@2|Bacteria,1U8E4@1239|Firmicutes,2499W@186801|Clostridia,21ZIM@1506553|Lachnoclostridium	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
NFNHFNFO_00183	742723.HMPREF9477_00355	5.84e-175	492.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,24DGQ@186801|Clostridia,27M0Q@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
NFNHFNFO_00185	457421.CBFG_00149	4.66e-84	251.0	COG1335@1|root,COG1335@2|Bacteria,1TQTE@1239|Firmicutes,24BQ4@186801|Clostridia	186801|Clostridia	Q	Isochorismatase family	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
NFNHFNFO_00186	457421.CBFG_00150	3.72e-194	541.0	COG2378@1|root,COG2378@2|Bacteria,1TT23@1239|Firmicutes,248A8@186801|Clostridia	186801|Clostridia	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
NFNHFNFO_00187	411902.CLOBOL_00564	6.41e-07	47.8	29HZ9@1|root,304WA@2|Bacteria,1UECC@1239|Firmicutes,25J86@186801|Clostridia,221JT@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00188	33035.JPJF01000009_gene1559	7.39e-278	763.0	COG2206@1|root,COG2206@2|Bacteria,1TS2E@1239|Firmicutes,249S8@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
NFNHFNFO_00189	33035.JPJF01000009_gene1558	2.41e-77	245.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia,3Y14Y@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	3.2.1.37	ko:K01198	ko00520,ko01100,map00520,map01100	-	R01433	RC00467	ko00000,ko00001,ko01000	-	GH43	-	Glyco_hydro_43
NFNHFNFO_00190	33035.JPJF01000009_gene1557	4.39e-106	318.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3XZZ6@572511|Blautia	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_00191	33035.JPJF01000009_gene1557	1.02e-19	87.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3XZZ6@572511|Blautia	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_00192	33035.JPJF01000009_gene1556	9.14e-283	772.0	COG2730@1|root,COG2730@2|Bacteria,1TS9M@1239|Firmicutes,24DA9@186801|Clostridia,3XZ6Z@572511|Blautia	186801|Clostridia	G	Cellulase (glycosyl hydrolase family 5)	-	-	-	-	-	-	-	-	-	-	-	-	Cellulase
NFNHFNFO_00193	33035.JPJF01000009_gene1555	4.37e-253	698.0	COG2207@1|root,COG2207@2|Bacteria,1TQD7@1239|Firmicutes,24DSW@186801|Clostridia,3Y1J2@572511|Blautia	1239|Firmicutes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
NFNHFNFO_00194	33035.JPJF01000009_gene1554	1.13e-250	689.0	COG0371@1|root,COG0371@2|Bacteria,1TQFU@1239|Firmicutes,248KH@186801|Clostridia,3XZGH@572511|Blautia	186801|Clostridia	C	COG COG0371 Glycerol dehydrogenase and related enzymes	dhaD	-	1.1.1.6	ko:K00005	ko00561,ko00640,ko01100,map00561,map00640,map01100	-	R01034,R10715,R10717	RC00029,RC00117,RC00670	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NFNHFNFO_00195	33035.JPJF01000009_gene1553	0.0	1100.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,3Y0AT@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NFNHFNFO_00196	33035.JPJF01000009_gene1552	8.52e-168	470.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_00197	33035.JPJF01000009_gene1551	1.52e-206	575.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,3Y000@572511|Blautia	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
NFNHFNFO_00198	33035.JPJF01000009_gene1550	1.2e-137	391.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,3Y06R@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00199	33035.JPJF01000009_gene1549	0.0	923.0	COG2509@1|root,COG2509@2|Bacteria,1TP9I@1239|Firmicutes,247QM@186801|Clostridia,3XZRA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07137	-	-	-	-	ko00000	-	-	-	FAD_binding_2,HI0933_like,Pyr_redox_2,Thi4
NFNHFNFO_00200	33035.JPJF01000009_gene1548	8.08e-112	323.0	COG2059@1|root,COG2059@2|Bacteria,1V5EX@1239|Firmicutes,24HY8@186801|Clostridia,3Y2BZ@572511|Blautia	186801|Clostridia	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
NFNHFNFO_00201	33035.JPJF01000009_gene1547	2.58e-109	317.0	COG2059@1|root,COG2059@2|Bacteria,1V22C@1239|Firmicutes,24H9X@186801|Clostridia,3Y2BY@572511|Blautia	186801|Clostridia	P	Chromate transporter	-	-	-	-	-	-	-	-	-	-	-	-	Chromate_transp
NFNHFNFO_00202	33035.JPJF01000009_gene1546	4.2e-175	492.0	COG0583@1|root,COG0583@2|Bacteria,1TNZR@1239|Firmicutes,25C6R@186801|Clostridia	186801|Clostridia	K	LysR substrate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_00203	1235792.C808_02156	5.94e-75	225.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,27MSR@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, gntR family	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NFNHFNFO_00204	33035.JPJF01000009_gene1544	1.31e-187	523.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3XZ9A@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_00205	33035.JPJF01000009_gene1543	1.02e-126	363.0	2E33N@1|root,32Y3S@2|Bacteria,1VFAP@1239|Firmicutes,24R1K@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
NFNHFNFO_00206	33035.JPJF01000009_gene1542	0.0	1409.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3XYNU@572511|Blautia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran,Transglut_core
NFNHFNFO_00207	33035.JPJF01000009_gene1540	9.27e-190	531.0	COG3173@1|root,COG3173@2|Bacteria,1U6NE@1239|Firmicutes,2489R@186801|Clostridia	186801|Clostridia	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
NFNHFNFO_00208	33035.JPJF01000009_gene1539	0.0	875.0	COG0488@1|root,COG0488@2|Bacteria,1TNYS@1239|Firmicutes,248D6@186801|Clostridia,3XZ6M@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K19350	ko02010,map02010	-	-	-	ko00000,ko00001,ko01504,ko02000	3.A.1.121	-	-	ABC_tran
NFNHFNFO_00210	33035.JPJF01000009_gene1536	3.22e-165	468.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,24AQE@186801|Clostridia,3XZNY@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	Peptidase_S11
NFNHFNFO_00211	33035.JPJF01000009_gene1535	2.3e-213	596.0	COG5002@1|root,COG5002@2|Bacteria,1TPB6@1239|Firmicutes,24AV5@186801|Clostridia,3XZYQ@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	2.7.13.3	ko:K18350	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko01504,ko02022	-	-	-	HAMP,HATPase_c,HisKA
NFNHFNFO_00212	33035.JPJF01000009_gene1534	6.43e-160	449.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3XZCU@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K18349	ko01502,ko02020,map01502,map02020	M00652,M00657	-	-	ko00000,ko00001,ko00002,ko01504,ko02022	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00213	33035.JPJF01000009_gene1533	4.92e-79	238.0	COG0745@1|root,COG0745@2|Bacteria,1VGWK@1239|Firmicutes,24SIJ@186801|Clostridia	186801|Clostridia	KT	Sporulation initiation factor Spo0A C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Spo0A_C
NFNHFNFO_00214	33035.JPJF01000009_gene1532	3.45e-159	448.0	COG1476@1|root,COG1476@2|Bacteria,1UIFY@1239|Firmicutes,24BCF@186801|Clostridia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
NFNHFNFO_00215	33035.JPJF01000009_gene1531	2.73e-108	315.0	2DK34@1|root,308A7@2|Bacteria,1U33E@1239|Firmicutes,259PD@186801|Clostridia,3Y21K@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00216	33035.JPJF01000009_gene1530	9.23e-249	689.0	28IVE@1|root,2Z8TU@2|Bacteria,1UYXD@1239|Firmicutes,24CW0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
NFNHFNFO_00217	33035.JPJF01000009_gene1529	4.24e-191	532.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3XZ40@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_00218	33035.JPJF01000009_gene1528	4.36e-244	676.0	COG0642@1|root,COG2205@2|Bacteria,1TRZX@1239|Firmicutes,249AI@186801|Clostridia,3XYP2@572511|Blautia	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NFNHFNFO_00219	33035.JPJF01000009_gene1527	5.22e-150	424.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,3XZRP@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00220	33035.JPJF01000009_gene1526	7.41e-199	552.0	COG2017@1|root,COG2017@2|Bacteria,1U26T@1239|Firmicutes,24AQ8@186801|Clostridia,3XZNJ@572511|Blautia	186801|Clostridia	G	COG COG2017 Galactose mutarotase and related enzymes	lacX	-	-	-	-	-	-	-	-	-	-	-	Aldose_epim
NFNHFNFO_00221	33035.JPJF01000009_gene1525	2.88e-306	837.0	COG0371@1|root,COG0371@2|Bacteria,1TR6W@1239|Firmicutes,25AGX@186801|Clostridia,3XZXG@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH_2
NFNHFNFO_00222	33035.JPJF01000009_gene1524	1.66e-60	192.0	COG4639@1|root,COG4639@2|Bacteria,1TU32@1239|Firmicutes,25NIJ@186801|Clostridia,3Y25J@572511|Blautia	186801|Clostridia	S	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00223	33035.JPJF01000009_gene1523	2.48e-156	441.0	COG1349@1|root,COG1349@2|Bacteria,1V27B@1239|Firmicutes,24DD2@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DeoRC,HTH_DeoR
NFNHFNFO_00224	33035.JPJF01000009_gene1522	1.17e-247	681.0	COG1609@1|root,COG1609@2|Bacteria,1UYY5@1239|Firmicutes,24C8C@186801|Clostridia,3XZ1C@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NFNHFNFO_00225	1280694.AUJQ01000001_gene2144	5.39e-70	213.0	COG0454@1|root,COG0456@2|Bacteria,1V8KY@1239|Firmicutes,24J02@186801|Clostridia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
NFNHFNFO_00226	33035.JPJF01000009_gene1520	2e-58	182.0	COG1388@1|root,COG1388@2|Bacteria,1VK5T@1239|Firmicutes,25DQN@186801|Clostridia,3Y0UF@572511|Blautia	186801|Clostridia	M	Inhibits cell division during the SOS response. Affects a later stage of the cell division protein assembly, after the assembly of the Z ring, by probably suppressing recruitment of FtsL and or DivIC to the division machinery	-	-	-	-	-	-	-	-	-	-	-	-	LysM
NFNHFNFO_00227	33035.JPJF01000009_gene1519	1.2e-131	374.0	COG1974@1|root,COG1974@2|Bacteria,1TQ3H@1239|Firmicutes,24AXJ@186801|Clostridia,3XYNM@572511|Blautia	186801|Clostridia	L	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair	lexA	-	3.4.21.88	ko:K01356	-	M00729	-	-	ko00000,ko00002,ko01000,ko01002,ko03400	-	-	-	LexA_DNA_bind,Peptidase_S24
NFNHFNFO_00228	33035.JPJF01000009_gene1518	4e-76	227.0	COG0799@1|root,COG0799@2|Bacteria,1VA2Z@1239|Firmicutes,24MVA@186801|Clostridia,3Y07Y@572511|Blautia	186801|Clostridia	J	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation	rsfS	-	-	ko:K09710	-	-	-	-	ko00000,ko03009	-	-	-	RsfS
NFNHFNFO_00229	33035.JPJF01000009_gene1517	9.85e-133	377.0	COG1713@1|root,COG1713@2|Bacteria,1V6Y1@1239|Firmicutes,24HN2@186801|Clostridia,3XYUN@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like,HD
NFNHFNFO_00230	33035.JPJF01000009_gene1516	2.24e-153	430.0	COG1057@1|root,COG1057@2|Bacteria,1V3SK@1239|Firmicutes,24JFM@186801|Clostridia,3XZHC@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)	nadD	-	2.7.7.18	ko:K00969	ko00760,ko01100,map00760,map01100	M00115	R00137,R03005	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
NFNHFNFO_00231	33035.JPJF01000009_gene1515	2.38e-56	176.0	COG1534@1|root,COG1534@2|Bacteria,1VEGM@1239|Firmicutes,24QZB@186801|Clostridia,3Y0BI@572511|Blautia	186801|Clostridia	J	RNA-binding protein containing KH domain, possibly ribosomal protein	yhbY	-	-	ko:K07574	-	-	-	-	ko00000,ko03009	-	-	-	CRS1_YhbY
NFNHFNFO_00232	33035.JPJF01000009_gene1514	4.41e-306	835.0	COG0536@1|root,COG0536@2|Bacteria,1TPX7@1239|Firmicutes,247SP@186801|Clostridia,3XYJQ@572511|Blautia	186801|Clostridia	S	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control	obg	-	-	ko:K03979	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	DUF1967,GTP1_OBG,MMR_HSR1
NFNHFNFO_00233	33035.JPJF01000009_gene1513	6.25e-60	184.0	COG0211@1|root,COG0211@2|Bacteria,1V6HW@1239|Firmicutes,24N3D@186801|Clostridia,3Y06C@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL27 family	rpmA	-	-	ko:K02899	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27
NFNHFNFO_00234	33035.JPJF01000009_gene1512	1.01e-68	208.0	COG2868@1|root,COG2868@2|Bacteria,1VCNG@1239|Firmicutes,25N63@186801|Clostridia,3Y0KN@572511|Blautia	186801|Clostridia	J	Cysteine protease Prp	-	-	-	ko:K07584	-	-	-	-	ko00000	-	-	-	Peptidase_Prp
NFNHFNFO_00235	33035.JPJF01000009_gene1511	9.42e-63	192.0	COG0261@1|root,COG0261@2|Bacteria,1V9YH@1239|Firmicutes,24MRS@186801|Clostridia,3Y060@572511|Blautia	186801|Clostridia	J	This protein binds to 23S rRNA in the presence of protein L20	rplU	-	-	ko:K02888	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L21p
NFNHFNFO_00236	33035.JPJF01000009_gene1510	6.64e-216	598.0	COG1266@1|root,COG1266@2|Bacteria,1VJMM@1239|Firmicutes,25AQE@186801|Clostridia,3Y0B9@572511|Blautia	186801|Clostridia	S	CAAX amino terminal protease family protein	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
NFNHFNFO_00237	33035.JPJF01000009_gene1509	3.5e-117	335.0	COG1051@1|root,COG1051@2|Bacteria,1V3IM@1239|Firmicutes,24HEA@186801|Clostridia,3Y016@572511|Blautia	186801|Clostridia	F	NUDIX domain	mutX	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
NFNHFNFO_00238	33035.JPJF01000009_gene1508	2.89e-245	679.0	COG1530@1|root,COG1530@2|Bacteria,1TQS4@1239|Firmicutes,247QV@186801|Clostridia,3XYXV@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	rng	-	-	ko:K08301	-	-	-	-	ko00000,ko01000,ko03009,ko03019	-	-	-	RNase_E_G,S1,TRAM
NFNHFNFO_00239	33035.JPJF01000009_gene1507	1.41e-146	415.0	COG5011@1|root,COG5011@2|Bacteria,1V4D0@1239|Firmicutes,249GU@186801|Clostridia,3XZQP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2344
NFNHFNFO_00240	33035.JPJF01000009_gene1506	0.0	1222.0	COG1032@1|root,COG1032@2|Bacteria,1TR2C@1239|Firmicutes,248HM@186801|Clostridia,3XYP5@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NFNHFNFO_00241	457421.CBFG_00975	3.07e-66	202.0	COG1733@1|root,COG1733@2|Bacteria,1VA9M@1239|Firmicutes,24KBG@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
NFNHFNFO_00242	457421.CBFG_00976	8.25e-78	233.0	COG5015@1|root,COG5015@2|Bacteria,1V43Y@1239|Firmicutes,24HQB@186801|Clostridia	186801|Clostridia	K	PFAM pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
NFNHFNFO_00243	658086.HMPREF0994_04045	1.17e-66	213.0	COG1476@1|root,COG1476@2|Bacteria,1UXTP@1239|Firmicutes,24CUB@186801|Clostridia,27PKV@186928|unclassified Lachnospiraceae	186801|Clostridia	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_00245	553973.CLOHYLEM_06396	3.01e-178	497.0	COG2227@1|root,COG2227@2|Bacteria,1TR7Z@1239|Firmicutes,248FI@186801|Clostridia	186801|Clostridia	H	Methyltransferase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
NFNHFNFO_00246	1226325.HMPREF1548_00271	2.81e-131	393.0	COG3452@1|root,COG5001@1|root,COG3452@2|Bacteria,COG5001@2|Bacteria,1VRUY@1239|Firmicutes,25EFD@186801|Clostridia,36UNW@31979|Clostridiaceae	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,GGDEF
NFNHFNFO_00250	1291050.JAGE01000001_gene3000	2.31e-115	338.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,3WHGU@541000|Ruminococcaceae	186801|Clostridia	P	ABC transporter	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NFNHFNFO_00251	1195236.CTER_1697	5.74e-94	283.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,3WGZB@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport system permease component	-	-	-	ko:K02050,ko:K15552	ko00920,ko02010,map00920,map02010	M00188,M00435	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.4	-	-	BPD_transp_1
NFNHFNFO_00252	1514668.JOOA01000001_gene768	1.71e-100	305.0	COG0715@1|root,COG0715@2|Bacteria,1TRT8@1239|Firmicutes,24A1D@186801|Clostridia,3WICD@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type nitrate sulfonate bicarbonate transport	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
NFNHFNFO_00253	1195236.CTER_1695	0.0	971.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,3WH69@541000|Ruminococcaceae	186801|Clostridia	C	TIGRFAM carbon-monoxide dehydrogenase, catalytic subunit	cooS	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
NFNHFNFO_00254	428126.CLOSPI_00716	7.92e-139	398.0	COG1409@1|root,COG1409@2|Bacteria,1TT7M@1239|Firmicutes	1239|Firmicutes	S	Carbohydrate esterase, sialic acid-specific acetylesterase	-	-	-	-	-	-	-	-	-	-	-	-	SASA
NFNHFNFO_00255	457421.CBFG_02539	2.94e-303	832.0	COG2186@1|root,COG2186@2|Bacteria,1TSP3@1239|Firmicutes,24DQE@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
NFNHFNFO_00256	411902.CLOBOL_02912	1.27e-132	377.0	COG0110@1|root,COG0110@2|Bacteria,1TPKX@1239|Firmicutes,249X2@186801|Clostridia,21ZGM@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 9.65	vat	-	-	ko:K18234	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Hexapep
NFNHFNFO_00257	411902.CLOBOL_02911	8.78e-301	831.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,222E9@1506553|Lachnoclostridium	186801|Clostridia	S	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
NFNHFNFO_00258	658086.HMPREF0994_00188	9.15e-97	296.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,27JE6@186928|unclassified Lachnospiraceae	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_00259	1540257.JQMW01000004_gene355	3.89e-90	271.0	2E2I5@1|root,32XMX@2|Bacteria,1VC1W@1239|Firmicutes,24H3A@186801|Clostridia,36I8E@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00260	1410624.JNKK01000013_gene1496	4.66e-36	131.0	COG3153@1|root,COG5470@1|root,COG3153@2|Bacteria,COG5470@2|Bacteria,1V3PW@1239|Firmicutes,24ACS@186801|Clostridia,27IX9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7,Acetyltransf_9
NFNHFNFO_00261	553973.CLOHYLEM_06392	1.52e-175	491.0	COG1357@1|root,COG1357@2|Bacteria,1TR7Y@1239|Firmicutes,2482A@186801|Clostridia,22289@1506553|Lachnoclostridium	186801|Clostridia	S	Pentapeptide repeats (8 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide
NFNHFNFO_00262	272563.CD630_17210	4.39e-94	278.0	COG3797@1|root,COG3797@2|Bacteria,1UY7E@1239|Firmicutes,25CR1@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1697)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1697
NFNHFNFO_00263	411902.CLOBOL_04625	4.36e-74	226.0	COG4845@1|root,COG4845@2|Bacteria,1V9NV@1239|Firmicutes,24FCQ@186801|Clostridia,21Y0Q@1506553|Lachnoclostridium	186801|Clostridia	V	Chloramphenicol acetyltransferase	-	-	2.3.1.28	ko:K19271	-	-	-	-	br01600,ko00000,ko01000,ko01504	-	-	-	CAT
NFNHFNFO_00264	553973.CLOHYLEM_04103	1.13e-102	300.0	2BXP4@1|root,2ZBZG@2|Bacteria,1V1ZR@1239|Firmicutes,24GRV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00265	553973.CLOHYLEM_06393	1.39e-132	381.0	COG0500@1|root,COG2226@2|Bacteria,1UVHG@1239|Firmicutes,25KIB@186801|Clostridia,221KJ@1506553|Lachnoclostridium	186801|Clostridia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
NFNHFNFO_00268	33035.JPJF01000048_gene690	6.02e-91	269.0	29299@1|root,2ZPTU@2|Bacteria,1V5UQ@1239|Firmicutes,24I5P@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00269	457421.CBFG_00331	1.65e-38	130.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QPB@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_19,HTH_3
NFNHFNFO_00270	457421.CBFG_00332	4.78e-87	258.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def2	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
NFNHFNFO_00271	1235802.C823_06156	2.57e-159	447.0	COG4422@1|root,COG4422@2|Bacteria,1TPP1@1239|Firmicutes,248RZ@186801|Clostridia,25W5Q@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF5131)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4186,DUF5131
NFNHFNFO_00272	1123075.AUDP01000004_gene839	6.42e-133	384.0	COG0789@1|root,COG0789@2|Bacteria,1TQYF@1239|Firmicutes,25B18@186801|Clostridia,3WIBA@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
NFNHFNFO_00273	411490.ANACAC_01173	3.21e-85	255.0	COG3708@1|root,COG3708@2|Bacteria,1V29U@1239|Firmicutes,24GZS@186801|Clostridia	186801|Clostridia	K	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cass2
NFNHFNFO_00274	556261.HMPREF0240_02203	1.18e-58	189.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,2496K@186801|Clostridia,36EDW@31979|Clostridiaceae	186801|Clostridia	K	transcription activator, effector binding	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like,HTH_18
NFNHFNFO_00275	658086.HMPREF0994_00186	1.76e-85	253.0	COG3871@1|root,COG3871@2|Bacteria,1V6IU@1239|Firmicutes,24G5S@186801|Clostridia,27N8Q@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase like	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx,Pyrid_ox_like
NFNHFNFO_00276	658086.HMPREF0994_00187	3.02e-67	205.0	COG1733@1|root,COG1733@2|Bacteria,1V70C@1239|Firmicutes,24HID@186801|Clostridia,27MS8@186928|unclassified Lachnospiraceae	186801|Clostridia	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
NFNHFNFO_00277	1226325.HMPREF1548_04024	4.56e-116	335.0	COG1396@1|root,COG1917@1|root,COG1396@2|Bacteria,COG1917@2|Bacteria,1V5G6@1239|Firmicutes,24928@186801|Clostridia,36GWJ@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_3
NFNHFNFO_00279	1226325.HMPREF1548_05884	9.8e-122	352.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,36I6U@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_00280	469596.HMPREF9488_01204	1.16e-142	412.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,3VPWI@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cass2,HTH_18
NFNHFNFO_00281	457421.CBFG_05525	6.16e-130	372.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_00282	457421.CBFG_05526	0.0	1144.0	COG0577@1|root,COG0577@2|Bacteria,1TRE5@1239|Firmicutes,24CGY@186801|Clostridia	186801|Clostridia	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NFNHFNFO_00283	457421.CBFG_05527	1.21e-194	554.0	COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,24AAW@186801|Clostridia,26A1A@186813|unclassified Clostridiales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_00284	457421.CBFG_05529	4.31e-142	404.0	COG0745@1|root,COG0745@2|Bacteria,1TPRM@1239|Firmicutes,25B4D@186801|Clostridia,26B27@186813|unclassified Clostridiales	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00285	545696.HOLDEFILI_03803	1.82e-93	297.0	COG0584@1|root,COG4781@1|root,COG0584@2|Bacteria,COG4781@2|Bacteria,1UGF1@1239|Firmicutes,3VQNH@526524|Erysipelotrichia	526524|Erysipelotrichia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
NFNHFNFO_00287	536227.CcarbDRAFT_2079	4.86e-113	331.0	COG4200@1|root,COG4200@2|Bacteria,1UY6Y@1239|Firmicutes,25EWV@186801|Clostridia,36HS2@31979|Clostridiaceae	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K19310	ko02010,map02010	M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.131.1	-	-	ABC2_membrane_4
NFNHFNFO_00288	272563.CD630_03170	7.81e-115	335.0	COG4200@1|root,COG4200@2|Bacteria,1V0P5@1239|Firmicutes,24BU1@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K19310	ko02010,map02010	M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.131.1	-	-	ABC2_membrane_4
NFNHFNFO_00289	1122918.KB907267_gene12	1.01e-185	520.0	COG1131@1|root,COG1131@2|Bacteria,1TPBQ@1239|Firmicutes,4HAGA@91061|Bacilli,274EC@186822|Paenibacillaceae	91061|Bacilli	V	Bacitracin ABC transporter, ATP-binding protein	potA3	-	-	ko:K01990,ko:K19309	ko02010,map02010	M00254,M00747	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.131.1	-	-	ABC_tran
NFNHFNFO_00290	748727.CLJU_c00810	2.76e-164	466.0	COG5002@1|root,COG5002@2|Bacteria,1UIAP@1239|Firmicutes,25EFU@186801|Clostridia,36UP8@31979|Clostridiaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_00291	748727.CLJU_c00820	9.96e-134	382.0	COG0745@1|root,COG0745@2|Bacteria,1TSCM@1239|Firmicutes,248K7@186801|Clostridia,36FU9@31979|Clostridiaceae	186801|Clostridia	KT	response regulator, receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00292	658086.HMPREF0994_05657	0.0	1216.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,27UFD@186928|unclassified Lachnospiraceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PocR,Response_reg
NFNHFNFO_00293	658086.HMPREF0994_05658	0.0	1016.0	COG0737@1|root,COG1653@1|root,COG0737@2|Bacteria,COG1653@2|Bacteria,1UW4I@1239|Firmicutes,25KQK@186801|Clostridia,27SXV@186928|unclassified Lachnospiraceae	186801|Clostridia	FG	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_00295	457421.CBFG_05443	1.48e-192	541.0	COG0225@1|root,COG0229@1|root,COG0225@2|Bacteria,COG0229@2|Bacteria,1TQ3E@1239|Firmicutes,247UT@186801|Clostridia,268SE@186813|unclassified Clostridiales	186801|Clostridia	O	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine	msrA	-	1.8.4.11,1.8.4.12	ko:K07304,ko:K12267	-	-	-	-	ko00000,ko01000	-	-	-	PMSR,Rhodanese,SelR
NFNHFNFO_00296	33035.JPJF01000009_gene1478	3.48e-15	72.8	COG0655@1|root,COG0655@2|Bacteria,1V1FU@1239|Firmicutes,24FWC@186801|Clostridia	186801|Clostridia	S	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NFNHFNFO_00297	33035.JPJF01000009_gene1477	1.15e-100	295.0	COG0350@1|root,COG0350@2|Bacteria,1V2MB@1239|Firmicutes,24HJ0@186801|Clostridia	186801|Clostridia	L	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated	-	-	2.1.1.63	ko:K00567	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DNA_binding_1,Methyltransf_1N
NFNHFNFO_00298	1280681.AUJZ01000005_gene3202	2.28e-132	380.0	COG0030@1|root,COG0030@2|Bacteria,1TPC0@1239|Firmicutes,24ADN@186801|Clostridia,4BWTP@830|Butyrivibrio	186801|Clostridia	J	Ribosomal RNA adenine dimethylase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,RrnaAD
NFNHFNFO_00299	33035.JPJF01000009_gene1463	1.42e-103	302.0	COG4430@1|root,COG4430@2|Bacteria,1V1VF@1239|Firmicutes,249ZH@186801|Clostridia	186801|Clostridia	S	Bacteriocin-protection, YdeI or OmpD-Associated	-	-	-	-	-	-	-	-	-	-	-	-	OmdA
NFNHFNFO_00300	33035.JPJF01000009_gene1462	1.42e-146	416.0	COG0842@1|root,COG0842@2|Bacteria,1TPZY@1239|Firmicutes,2482T@186801|Clostridia,3XZQ7@572511|Blautia	186801|Clostridia	V	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
NFNHFNFO_00301	33035.JPJF01000009_gene1461	5.85e-149	422.0	COG1131@1|root,COG1131@2|Bacteria,1TQTX@1239|Firmicutes,249W1@186801|Clostridia,3XZ4S@572511|Blautia	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_00302	33035.JPJF01000009_gene1460	7.46e-145	412.0	COG0789@1|root,COG0789@2|Bacteria,1TQ78@1239|Firmicutes,247ZI@186801|Clostridia,3XZ8J@572511|Blautia	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NFNHFNFO_00303	33035.JPJF01000009_gene1453	1.35e-15	71.6	COG0642@1|root,COG2205@2|Bacteria,1VBSA@1239|Firmicutes,24NVV@186801|Clostridia	186801|Clostridia	T	Protein of unknown function (DUF2809)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2809
NFNHFNFO_00304	33035.JPJF01000009_gene1452	7.03e-35	129.0	COG0500@1|root,COG3153@1|root,COG0500@2|Bacteria,COG3153@2|Bacteria,1UHZW@1239|Firmicutes,25E8K@186801|Clostridia	186801|Clostridia	Q	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25,Methyltransf_31
NFNHFNFO_00305	33035.JPJF01000009_gene1447	0.0	1309.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3XYX5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NFNHFNFO_00306	33035.JPJF01000009_gene1446	2.63e-173	485.0	COG2169@1|root,COG4977@1|root,COG2169@2|Bacteria,COG4977@2|Bacteria,1UHZV@1239|Firmicutes,25E8J@186801|Clostridia,3Y12E@572511|Blautia	186801|Clostridia	F	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_00307	33035.JPJF01000009_gene1430	0.0	1373.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3XYNU@572511|Blautia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	-	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
NFNHFNFO_00308	33035.JPJF01000009_gene1426	1.79e-150	429.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1TTBG@1239|Firmicutes,24CWB@186801|Clostridia,3Y13J@572511|Blautia	186801|Clostridia	KT	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
NFNHFNFO_00309	33035.JPJF01000009_gene1425	1.52e-191	536.0	COG1680@1|root,COG1680@2|Bacteria,1W747@1239|Firmicutes,256Q7@186801|Clostridia,3Y0WX@572511|Blautia	186801|Clostridia	V	COG1680 Beta-lactamase class C and other penicillin binding	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase
NFNHFNFO_00310	1487921.DP68_18175	1.28e-44	155.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,36IAW@31979|Clostridiaceae	186801|Clostridia	K	GntR family	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NFNHFNFO_00311	1123075.AUDP01000004_gene873	1.65e-105	317.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia,3WP2Y@541000|Ruminococcaceae	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_00312	742740.HMPREF9474_01625	1.48e-190	541.0	COG2768@1|root,COG2768@2|Bacteria,1TPRV@1239|Firmicutes,247PJ@186801|Clostridia,21Z0M@1506553|Lachnoclostridium	186801|Clostridia	C	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088,DUF362
NFNHFNFO_00313	742740.HMPREF9474_03014	5.26e-171	492.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,21ZGS@1506553|Lachnoclostridium	186801|Clostridia	G	COG COG1593 TRAP-type C4-dicarboxylate transport system, large permease component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
NFNHFNFO_00314	1487921.DP68_18165	2.32e-36	130.0	COG3090@1|root,COG3090@2|Bacteria,1V3PZ@1239|Firmicutes,24HA7@186801|Clostridia,36PE8@31979|Clostridiaceae	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
NFNHFNFO_00315	1487921.DP68_18170	3.76e-80	256.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,248MN@186801|Clostridia,36VS7@31979|Clostridiaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
NFNHFNFO_00316	1105031.HMPREF1141_1070	1.58e-66	204.0	COG1786@1|root,COG1786@2|Bacteria,1V4V4@1239|Firmicutes,24I6P@186801|Clostridia,36RXC@31979|Clostridiaceae	186801|Clostridia	S	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
NFNHFNFO_00317	1121334.KB911069_gene1462	3.03e-248	686.0	COG1679@1|root,COG1679@2|Bacteria,1UJDG@1239|Firmicutes,24DTH@186801|Clostridia,3WK5V@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
NFNHFNFO_00318	33035.JPJF01000009_gene1424	2.01e-97	285.0	COG0454@1|root,COG0456@2|Bacteria,1UHZS@1239|Firmicutes,25E8H@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_00319	658086.HMPREF0994_00687	3.38e-26	106.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,27J2J@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Cation efflux family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
NFNHFNFO_00320	33035.JPJF01000009_gene1422	0.0	900.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia	186801|Clostridia	K	aminotransferase class I and II	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_1_2,GntR
NFNHFNFO_00321	33035.JPJF01000009_gene1421	1.03e-266	732.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,3Y1A6@572511|Blautia	186801|Clostridia	EK	Alanine-glyoxylate amino-transferase	-	-	-	ko:K05825	ko00300,ko01100,ko01130,ko01210,map00300,map01100,map01130,map01210	-	R01939	RC00006	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
NFNHFNFO_00322	33035.JPJF01000009_gene1418	1.35e-286	787.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZGC@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_00323	33035.JPJF01000009_gene1417	2.62e-195	547.0	COG5464@1|root,COG5464@2|Bacteria,1TYQI@1239|Firmicutes,24D7J@186801|Clostridia,3Y26P@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
NFNHFNFO_00325	33035.JPJF01000009_gene1416	0.0	1514.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3XZ5F@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	csdB	-	2.3.1.54,4.3.99.4	ko:K00656,ko:K20038	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NFNHFNFO_00326	33035.JPJF01000009_gene1415	8.28e-199	553.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,24871@186801|Clostridia,3Y098@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 9.98	csdA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4,Fer4_12,Radical_SAM
NFNHFNFO_00327	1243664.CAVL020000015_gene1843	8.54e-08	63.5	COG2508@1|root,COG2508@2|Bacteria,1TRDF@1239|Firmicutes,4H9KC@91061|Bacilli,1ZCWF@1386|Bacillus	91061|Bacilli	QT	COG2508 Regulator of polyketide synthase expression	pucR_2	-	-	ko:K09684	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30,PucR
NFNHFNFO_00328	545694.TREPR_1962	3.39e-92	284.0	COG0407@1|root,COG0407@2|Bacteria,2JAKX@203691|Spirochaetes	203691|Spirochaetes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
NFNHFNFO_00329	1232453.BAIF02000086_gene333	4.25e-103	303.0	COG1309@1|root,COG1309@2|Bacteria,1V3XC@1239|Firmicutes,24JC2@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_00330	33035.JPJF01000009_gene1411	4.48e-177	498.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,3XYP6@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	UPF0051
NFNHFNFO_00331	33035.JPJF01000009_gene1408	1.77e-98	286.0	COG4766@1|root,COG4766@2|Bacteria,1V498@1239|Firmicutes,25DES@186801|Clostridia	186801|Clostridia	E	ethanolamine	-	-	-	ko:K04030	-	-	-	-	ko00000	-	-	-	EutQ
NFNHFNFO_00332	33035.JPJF01000009_gene1407	7.44e-232	641.0	COG3192@1|root,COG3192@2|Bacteria,1TNZF@1239|Firmicutes,2483P@186801|Clostridia	186801|Clostridia	E	PFAM Ethanolamine utilisation protein, EutH	eutH	-	-	ko:K04023	-	-	-	-	ko00000	-	-	-	EutH
NFNHFNFO_00333	33035.JPJF01000009_gene1406	3.38e-51	162.0	COG4576@1|root,COG4576@2|Bacteria,1VEI4@1239|Firmicutes,24QJA@186801|Clostridia,3Y0FT@572511|Blautia	186801|Clostridia	CQ	COG COG4576 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	ko:K04028	-	-	-	-	ko00000	-	-	-	EutN_CcmL
NFNHFNFO_00334	33035.JPJF01000009_gene1405	2.09e-119	345.0	2E7RK@1|root,3326X@2|Bacteria,1VEHH@1239|Firmicutes,24JHV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00335	33035.JPJF01000009_gene1404	1.09e-138	393.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24816@186801|Clostridia,3Y0B2@572511|Blautia	186801|Clostridia	Q	Phosphate propanoyltransferase	pduL	-	-	-	-	-	-	-	-	-	-	-	PTAC
NFNHFNFO_00336	33035.JPJF01000009_gene1403	3.2e-131	373.0	COG4812@1|root,COG4812@2|Bacteria,1V18U@1239|Firmicutes,24D11@186801|Clostridia	186801|Clostridia	E	Cobalamin adenosyltransferase	eutT	-	2.5.1.17	ko:K04032	ko00860,ko01100,map00860,map01100	-	R01492	RC00533	ko00000,ko00001,ko01000	-	-	-	Cob_adeno_trans
NFNHFNFO_00337	33035.JPJF01000009_gene1402	3.05e-60	186.0	COG4577@1|root,COG4577@2|Bacteria,1VA0E@1239|Firmicutes,24N43@186801|Clostridia,3Y09W@572511|Blautia	186801|Clostridia	CQ	COG COG4577 Carbon dioxide concentrating mechanism carboxysome shell protein	-	-	-	ko:K04027	-	-	-	-	ko00000	-	-	-	BMC
NFNHFNFO_00338	33035.JPJF01000009_gene1401	0.0	874.0	COG1012@1|root,COG1012@2|Bacteria,1UHQT@1239|Firmicutes,25E5E@186801|Clostridia	186801|Clostridia	C	acetaldehyde dehydrogenase (acetylating)	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
NFNHFNFO_00339	33035.JPJF01000009_gene1400	7.1e-144	407.0	COG4816@1|root,COG4816@2|Bacteria,1TPAQ@1239|Firmicutes,248W6@186801|Clostridia	186801|Clostridia	E	ethanolamine utilization protein	eutL	-	-	ko:K04026	-	-	-	-	ko00000	-	-	-	BMC
NFNHFNFO_00340	33035.JPJF01000009_gene1399	4.82e-181	507.0	COG4302@1|root,COG4302@2|Bacteria,1TSZM@1239|Firmicutes,24A5Y@186801|Clostridia	186801|Clostridia	E	Belongs to the EutC family	eutC	-	4.3.1.7	ko:K03736	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutC
NFNHFNFO_00341	33035.JPJF01000009_gene1398	1.79e-310	847.0	COG4303@1|root,COG4303@2|Bacteria,1TP15@1239|Firmicutes,248P5@186801|Clostridia	186801|Clostridia	E	PFAM Ethanolamine ammonia lyase large subunit	eutB	-	4.3.1.7	ko:K03735	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001,ko01000	-	-	-	EutB
NFNHFNFO_00342	33035.JPJF01000009_gene1397	4.75e-306	838.0	COG4819@1|root,COG4819@2|Bacteria,1TQ6T@1239|Firmicutes,24BB7@186801|Clostridia	186801|Clostridia	E	PFAM Ethanolamine utilisation	eutA	-	-	ko:K04019	ko00564,ko01100,map00564,map01100	-	R00749	RC00370	ko00000,ko00001	-	-	-	EutA
NFNHFNFO_00343	33035.JPJF01000009_gene1396	1.71e-89	263.0	COG4917@1|root,COG4917@2|Bacteria,1VAYC@1239|Firmicutes,24F8T@186801|Clostridia,3XZTV@572511|Blautia	186801|Clostridia	E	Ethanolamine utilisation - propanediol utilisation	eutP	-	-	ko:K04029	-	-	-	-	ko00000	-	-	-	PduV-EutP
NFNHFNFO_00344	33035.JPJF01000009_gene1395	9.7e-73	219.0	COG4810@1|root,COG4810@2|Bacteria,1VB54@1239|Firmicutes,24JK9@186801|Clostridia,3Y01P@572511|Blautia	186801|Clostridia	E	BMC	pduU	-	-	ko:K04031	-	-	-	-	ko00000	-	-	-	BMC
NFNHFNFO_00345	33035.JPJF01000009_gene1394	1.02e-249	688.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XZNH@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NFNHFNFO_00346	33035.JPJF01000009_gene1393	2.96e-83	249.0	COG1905@1|root,COG1905@2|Bacteria,1VFWQ@1239|Firmicutes,24PUZ@186801|Clostridia,3Y0FI@572511|Blautia	186801|Clostridia	C	Thioredoxin-like [2Fe-2S] ferredoxin	-	-	-	-	-	-	-	-	-	-	-	-	2Fe-2S_thioredx
NFNHFNFO_00347	33035.JPJF01000009_gene1392	2.37e-293	801.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,25DH7@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_00348	33035.JPJF01000009_gene1391	0.0	1057.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,3Y10W@572511|Blautia	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NFNHFNFO_00349	33035.JPJF01000009_gene1390	4.81e-96	285.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,3Y1FF@572511|Blautia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_00350	1232453.BAIF02000085_gene376	3.5e-100	305.0	COG0642@1|root,COG0642@2|Bacteria,1V213@1239|Firmicutes,249E9@186801|Clostridia,26CMM@186813|unclassified Clostridiales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
NFNHFNFO_00351	33035.JPJF01000009_gene1388	3.63e-144	408.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,24B5K@186801|Clostridia,3Y1G3@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00352	658086.HMPREF0994_00088	8.9e-281	773.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,27J9K@186928|unclassified Lachnospiraceae	186801|Clostridia	V	MatE	effD	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_00353	357809.Cphy_1793	1.03e-125	364.0	COG0300@1|root,COG0300@2|Bacteria,1UZHA@1239|Firmicutes,248C8@186801|Clostridia,22452@1506553|Lachnoclostridium	186801|Clostridia	S	KR domain	-	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
NFNHFNFO_00354	445971.ANASTE_00990	1.2e-32	116.0	COG0640@1|root,COG0640@2|Bacteria,1VFY4@1239|Firmicutes	1239|Firmicutes	K	ArsR family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
NFNHFNFO_00355	33035.JPJF01000009_gene1387	2.39e-177	494.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,3XYW4@572511|Blautia	186801|Clostridia	D	Anion-transporting ATPase	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	AAA_31,CbiA
NFNHFNFO_00356	33035.JPJF01000009_gene1386	1.46e-133	379.0	COG1309@1|root,COG1309@2|Bacteria,1V6JC@1239|Firmicutes,24MPA@186801|Clostridia,3XZXC@572511|Blautia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_00357	33035.JPJF01000009_gene1385	6.57e-128	369.0	COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,24JPX@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
NFNHFNFO_00358	33035.JPJF01000009_gene1384	0.0	990.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3XZS3@572511|Blautia	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
NFNHFNFO_00359	33035.JPJF01000009_gene1383	2.13e-128	364.0	COG3331@1|root,COG3331@2|Bacteria,1V3S4@1239|Firmicutes,24G7S@186801|Clostridia,3XZTT@572511|Blautia	186801|Clostridia	L	Endonuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves mobile four-strand junctions by introducing symmetrical nicks in paired strands. Promotes annealing of linear ssDNA with homologous dsDNA. Required for DNA repair, homologous recombination and chromosome segregation	recU	-	-	ko:K03700	-	-	-	-	ko00000,ko03400	-	-	-	RecU
NFNHFNFO_00360	33035.JPJF01000009_gene1382	6.88e-125	355.0	COG0681@1|root,COG0681@2|Bacteria,1V7H9@1239|Firmicutes,24HHW@186801|Clostridia,3XZX6@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	lepB_1	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
NFNHFNFO_00361	33035.JPJF01000009_gene1381	2.51e-212	588.0	COG0564@1|root,COG0564@2|Bacteria,1TR1M@1239|Firmicutes,248W3@186801|Clostridia,3XYMC@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	rluC	-	5.4.99.24	ko:K06179	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NFNHFNFO_00362	33035.JPJF01000009_gene1380	9.8e-135	382.0	2E2IE@1|root,32XN3@2|Bacteria,1VD21@1239|Firmicutes,24PNW@186801|Clostridia,3Y2D4@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00363	33035.JPJF01000009_gene1379	9.83e-147	416.0	COG0300@1|root,COG0300@2|Bacteria,1V3UX@1239|Firmicutes,25B0Y@186801|Clostridia,3Y001@572511|Blautia	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	sdh	-	-	ko:K07124	-	-	-	-	ko00000	-	-	-	adh_short
NFNHFNFO_00364	33035.JPJF01000009_gene1378	0.0	1151.0	COG1032@1|root,COG1032@2|Bacteria,1TQ8X@1239|Firmicutes,248IW@186801|Clostridia,3XYGY@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3362,Radical_SAM,Radical_SAM_N
NFNHFNFO_00365	33035.JPJF01000009_gene1377	5.43e-156	438.0	COG0637@1|root,COG0637@2|Bacteria,1V1DF@1239|Firmicutes,24FYY@186801|Clostridia,3XZUV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
NFNHFNFO_00366	33035.JPJF01000009_gene1376	4.07e-145	412.0	COG1187@1|root,COG1187@2|Bacteria,1TQZ2@1239|Firmicutes,248HC@186801|Clostridia,3XZSS@572511|Blautia	186801|Clostridia	J	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate	rsuA	-	5.4.99.19	ko:K06183	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NFNHFNFO_00367	33035.JPJF01000009_gene1375	4.77e-290	796.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,3Y16W@572511|Blautia	186801|Clostridia	J	RNA-binding PUA-like domain of methyltransferase RsmF	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
NFNHFNFO_00368	33035.JPJF01000009_gene1374	9.72e-187	520.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,3XZGG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yjbM	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NFNHFNFO_00369	33035.JPJF01000009_gene1373	1.14e-146	416.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia,3Y0AB@572511|Blautia	186801|Clostridia	M	COG COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
NFNHFNFO_00370	33035.JPJF01000009_gene1372	0.0	919.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24860@186801|Clostridia,3XZA8@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	pepD	-	-	ko:K01270	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NFNHFNFO_00371	33035.JPJF01000038_gene441	5.93e-183	512.0	COG3314@1|root,COG3314@2|Bacteria,1TR0V@1239|Firmicutes,247XA@186801|Clostridia,3Y01Q@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	ylbJ	-	-	-	-	-	-	-	-	-	-	-	Gate
NFNHFNFO_00372	33035.JPJF01000038_gene442	2.98e-90	270.0	COG0711@1|root,COG0711@2|Bacteria,1V97P@1239|Firmicutes,24JGQ@186801|Clostridia,3XZBA@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00373	33035.JPJF01000038_gene443	3.22e-104	302.0	COG0669@1|root,COG0669@2|Bacteria,1V3MR@1239|Firmicutes,24HC3@186801|Clostridia,3XZXZ@572511|Blautia	186801|Clostridia	H	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate	coaD	-	2.7.7.3	ko:K00954	ko00770,ko01100,map00770,map01100	M00120	R03035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_like
NFNHFNFO_00374	33035.JPJF01000038_gene444	3.96e-126	359.0	COG0742@1|root,COG0742@2|Bacteria,1V3JF@1239|Firmicutes,24JHR@186801|Clostridia,3XZUU@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	rsmD	-	2.1.1.171	ko:K08316	-	-	R07234	RC00003	ko00000,ko01000,ko03009	-	-	-	Cons_hypoth95
NFNHFNFO_00375	33035.JPJF01000038_gene445	3.52e-92	269.0	COG1803@1|root,COG1803@2|Bacteria,1V3KQ@1239|Firmicutes,24FUQ@186801|Clostridia,3Y038@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	mgsA	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
NFNHFNFO_00376	33035.JPJF01000038_gene446	1.13e-39	132.0	2BX75@1|root,32YCI@2|Bacteria,1VEDY@1239|Firmicutes,24QPW@186801|Clostridia,3Y0GC@572511|Blautia	186801|Clostridia	S	COG NOG16862 non supervised orthologous group	sasP	-	-	ko:K06421	-	-	-	-	ko00000	-	-	-	SASP
NFNHFNFO_00377	33035.JPJF01000038_gene447	2.53e-41	141.0	2DRHG@1|root,33BRY@2|Bacteria,1VKXA@1239|Firmicutes,24UU3@186801|Clostridia,3Y0P6@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00378	33035.JPJF01000038_gene448	0.0	1350.0	COG0577@1|root,COG1511@1|root,COG0577@2|Bacteria,COG1511@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,3XYHV@572511|Blautia	186801|Clostridia	V	COG COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NFNHFNFO_00379	33035.JPJF01000038_gene449	0.0	1281.0	COG1200@1|root,COG1200@2|Bacteria,1TQ6I@1239|Firmicutes,247T0@186801|Clostridia,3XYJZ@572511|Blautia	186801|Clostridia	L	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)	recG	-	3.6.4.12	ko:K03655	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,RecG_wedge
NFNHFNFO_00380	33035.JPJF01000038_gene450	0.0	1015.0	COG1461@1|root,COG1461@2|Bacteria,1TQMX@1239|Firmicutes,247XI@186801|Clostridia,3XYY8@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07030	-	-	-	-	ko00000	-	-	-	Dak1_2,Dak2
NFNHFNFO_00381	33035.JPJF01000038_gene451	9.77e-73	219.0	COG1302@1|root,COG1302@2|Bacteria,1V731@1239|Firmicutes,24JIA@186801|Clostridia,3Y05W@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Asp23
NFNHFNFO_00382	476272.RUMHYD_00500	2.1e-37	125.0	COG0227@1|root,COG0227@2|Bacteria,1VEI2@1239|Firmicutes,24QNA@186801|Clostridia,3Y0NA@572511|Blautia	186801|Clostridia	J	COG COG0227 Ribosomal protein L28	rpmB	-	-	ko:K02902	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L28
NFNHFNFO_00383	33035.JPJF01000038_gene452	1.32e-70	215.0	COG3874@1|root,COG3874@2|Bacteria,1V99U@1239|Firmicutes,24K00@186801|Clostridia,3Y06K@572511|Blautia	186801|Clostridia	S	Sporulation protein YtfJ (Spore_YtfJ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YtfJ
NFNHFNFO_00384	33035.JPJF01000038_gene453	7.39e-147	424.0	2E3Z2@1|root,32YW0@2|Bacteria,1VGF4@1239|Firmicutes,24PIY@186801|Clostridia,3Y0BT@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF2953
NFNHFNFO_00385	33035.JPJF01000038_gene454	2.88e-69	209.0	2CSSR@1|root,2ZRRI@2|Bacteria,1W6GK@1239|Firmicutes,2540H@186801|Clostridia,3Y0MA@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00386	33035.JPJF01000038_gene455	0.0	963.0	COG2326@1|root,COG2326@2|Bacteria,1TQQR@1239|Firmicutes,249HE@186801|Clostridia,3XZ8V@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	pap	-	-	-	-	-	-	-	-	-	-	-	PPK2
NFNHFNFO_00387	33035.JPJF01000038_gene456	8.49e-105	302.0	COG1051@1|root,COG1051@2|Bacteria,1V4E6@1239|Firmicutes,24HPT@186801|Clostridia,3XZUN@572511|Blautia	186801|Clostridia	F	Belongs to the Nudix hydrolase family	apfA	-	-	-	-	-	-	-	-	-	-	-	NUDIX
NFNHFNFO_00388	33035.JPJF01000038_gene457	6.79e-303	830.0	COG0768@1|root,COG0768@2|Bacteria,1TPER@1239|Firmicutes,2486R@186801|Clostridia,3XYMX@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	pbpA2	-	-	ko:K05364	ko00550,map00550	-	R04519	RC00005,RC00049	ko00000,ko00001,ko01011	-	-	-	Transpeptidase
NFNHFNFO_00389	33035.JPJF01000038_gene458	6.26e-293	804.0	COG0772@1|root,COG0772@2|Bacteria,1TQ82@1239|Firmicutes,248QS@186801|Clostridia,3XYN1@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FHA,FTSW_RODA_SPOVE
NFNHFNFO_00390	33035.JPJF01000038_gene459	0.0	1290.0	COG0826@1|root,COG0826@2|Bacteria,1TQS1@1239|Firmicutes,24909@186801|Clostridia,3XYUZ@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	DUF3656,Peptidase_U32
NFNHFNFO_00391	33035.JPJF01000038_gene460	1.07e-82	245.0	COG3027@1|root,COG3027@2|Bacteria,1V4E5@1239|Firmicutes,24HQR@186801|Clostridia,3Y0AS@572511|Blautia	186801|Clostridia	D	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division	-	-	-	ko:K09888	-	-	-	-	ko00000,ko03036	-	-	-	ZapA
NFNHFNFO_00392	33035.JPJF01000038_gene461	4.86e-234	644.0	COG2255@1|root,COG2255@2|Bacteria,1TR47@1239|Firmicutes,247W0@186801|Clostridia,3XZK8@572511|Blautia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing	ruvB	-	3.6.4.12	ko:K03551	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	RuvB_C,RuvB_N
NFNHFNFO_00393	33035.JPJF01000038_gene462	4.13e-132	376.0	COG0632@1|root,COG0632@2|Bacteria,1V3KF@1239|Firmicutes,24JKV@186801|Clostridia,3XZX0@572511|Blautia	186801|Clostridia	L	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB	ruvA	-	3.6.4.12	ko:K03550	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HHH_5,RuvA_C,RuvA_N
NFNHFNFO_00394	33035.JPJF01000038_gene463	2.94e-90	267.0	COG4769@1|root,COG4769@2|Bacteria,1V1M0@1239|Firmicutes,24MZC@186801|Clostridia,3Y096@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	Hpre_diP_synt_I
NFNHFNFO_00395	33035.JPJF01000038_gene464	3.07e-67	205.0	COG5341@1|root,COG5341@2|Bacteria,1VEPD@1239|Firmicutes,24QPH@186801|Clostridia,3Y0GM@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	2.5.1.30	ko:K00805	ko00900,ko01110,map00900,map01110	-	R09247	RC00279	ko00000,ko00001,ko01000,ko01006	-	-	-	NusG_II
NFNHFNFO_00396	33035.JPJF01000038_gene465	8.58e-197	551.0	COG1477@1|root,COG1477@2|Bacteria,1TR9C@1239|Firmicutes,248KJ@186801|Clostridia,3XZKQ@572511|Blautia	186801|Clostridia	H	Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein	apbE	-	2.7.1.180	ko:K03734	-	-	-	-	ko00000,ko01000	-	-	-	ApbE
NFNHFNFO_00397	33035.JPJF01000038_gene466	9.4e-164	461.0	COG2768@1|root,COG2878@1|root,COG2768@2|Bacteria,COG2878@2|Bacteria,1TQGD@1239|Firmicutes,24904@186801|Clostridia,3XZFG@572511|Blautia	186801|Clostridia	C	F420-non-reducing hydrogenase	rnfB	-	-	ko:K03616	-	-	-	-	ko00000	-	-	-	FeS,Fer4,Fer4_13,Fer4_4,Fer4_9
NFNHFNFO_00398	33035.JPJF01000038_gene467	6.67e-123	352.0	COG4657@1|root,COG4657@2|Bacteria,1TS06@1239|Firmicutes,247UE@186801|Clostridia,3XYQD@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfA	-	-	ko:K03617	-	-	-	-	ko00000	-	-	-	Rnf-Nqr
NFNHFNFO_00399	33035.JPJF01000038_gene468	1.22e-156	440.0	COG4660@1|root,COG4660@2|Bacteria,1TSE7@1239|Firmicutes,24972@186801|Clostridia,3XYKR@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfE	-	-	ko:K03613	-	-	-	-	ko00000	-	-	iHN637.CLJU_RS05585	Rnf-Nqr
NFNHFNFO_00400	33035.JPJF01000038_gene469	2.54e-121	348.0	COG4659@1|root,COG4659@2|Bacteria,1V7R1@1239|Firmicutes,24JVM@186801|Clostridia,3XZTQ@572511|Blautia	186801|Clostridia	P	Part of a membrane complex involved in electron transport	rnfG	-	-	ko:K03612	-	-	-	-	ko00000	-	-	-	FMN_bind
NFNHFNFO_00401	33035.JPJF01000038_gene470	9.05e-214	591.0	COG4658@1|root,COG4658@2|Bacteria,1TQAY@1239|Firmicutes,247TM@186801|Clostridia,3XYSH@572511|Blautia	186801|Clostridia	C	Electron transport complex	rnfD	-	-	ko:K03614	-	-	-	-	ko00000	-	-	-	NQR2_RnfD_RnfE
NFNHFNFO_00402	33035.JPJF01000038_gene471	5.57e-305	833.0	COG4656@1|root,COG4656@2|Bacteria,1TPCC@1239|Firmicutes,24805@186801|Clostridia,3XYXE@572511|Blautia	186801|Clostridia	C	Part of a membrane complex involved in electron transport	rnfC	-	-	ko:K03615	-	-	-	-	ko00000	-	-	-	Complex1_51K,Fer4,Fer4_10,Fer4_7,Fer4_9,RnfC_N,SLBB
NFNHFNFO_00403	33035.JPJF01000038_gene472	1.88e-191	534.0	COG4905@1|root,COG4905@2|Bacteria,1V2HX@1239|Firmicutes,24B3D@186801|Clostridia,3Y072@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NFNHFNFO_00404	33035.JPJF01000038_gene473	9.91e-232	642.0	COG3359@1|root,COG3359@2|Bacteria,1U725@1239|Firmicutes,24A9V@186801|Clostridia,3Y0A0@572511|Blautia	186801|Clostridia	L	RNase_H superfamily	-	-	-	ko:K07502	-	-	-	-	ko00000	-	-	-	RNase_H_2
NFNHFNFO_00405	33035.JPJF01000038_gene474	7.05e-249	684.0	COG0539@1|root,COG0539@2|Bacteria,1TQ9N@1239|Firmicutes,247UK@186801|Clostridia,3XZ91@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB,S1
NFNHFNFO_00406	33035.JPJF01000038_gene475	1.17e-188	525.0	COG0761@1|root,COG0761@2|Bacteria,1UHT7@1239|Firmicutes,25E67@186801|Clostridia,3XYNX@572511|Blautia	186801|Clostridia	C	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis	ispH	-	1.17.7.4	ko:K02945,ko:K03527	ko00900,ko01100,ko01110,ko01130,ko03010,map00900,map01100,map01110,map01130,map03010	M00096,M00178	R05884,R08210	RC01137,RC01487	br01610,ko00000,ko00001,ko00002,ko01000,ko03011	-	-	-	LYTB
NFNHFNFO_00407	33035.JPJF01000038_gene476	6.95e-137	389.0	COG0283@1|root,COG0283@2|Bacteria,1V3IA@1239|Firmicutes,24HEF@186801|Clostridia,3XZMG@572511|Blautia	186801|Clostridia	F	Belongs to the cytidylate kinase family. Type 1 subfamily	cmk	-	2.7.4.25	ko:K00945	ko00240,ko01100,map00240,map01100	M00052	R00158,R00512,R01665	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Cytidylate_kin
NFNHFNFO_00408	33035.JPJF01000038_gene477	1.27e-273	751.0	COG2081@1|root,COG2081@2|Bacteria,1TQ6E@1239|Firmicutes,247S5@186801|Clostridia,3XYPF@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07007	-	-	-	-	ko00000	-	-	-	HI0933_like
NFNHFNFO_00409	33035.JPJF01000038_gene478	4.19e-210	582.0	COG1737@1|root,COG1737@2|Bacteria,1TP7H@1239|Firmicutes,248ZD@186801|Clostridia,3XZ7C@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NFNHFNFO_00411	33035.JPJF01000038_gene479	0.0	919.0	COG5016@1|root,COG5016@2|Bacteria,1VT8P@1239|Firmicutes,247NZ@186801|Clostridia,3XZ83@572511|Blautia	186801|Clostridia	C	Pyruvate carboxylase, C-terminal domain subunit	oadA	-	4.1.1.3	ko:K01571	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	HMGL-like,PYC_OADA
NFNHFNFO_00412	33035.JPJF01000038_gene480	2.12e-256	705.0	COG1883@1|root,COG1883@2|Bacteria,1TPEP@1239|Firmicutes,248ET@186801|Clostridia,3XZ7I@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	gcdB	-	4.1.1.3	ko:K01572	ko00620,ko01100,map00620,map01100	-	R00217	RC00040	ko00000,ko00001,ko01000,ko02000	3.B.1.1.1	-	-	OAD_beta
NFNHFNFO_00413	537007.BLAHAN_04888	5.62e-40	136.0	COG4770@1|root,COG4770@2|Bacteria,1VA1E@1239|Firmicutes,24MUJ@186801|Clostridia,3Y06B@572511|Blautia	186801|Clostridia	I	Biotin-requiring enzyme	gcdC	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl
NFNHFNFO_00414	33035.JPJF01000038_gene482	3.63e-153	433.0	2DNAY@1|root,32WHQ@2|Bacteria,1VDJJ@1239|Firmicutes,24R0U@186801|Clostridia,3Y289@572511|Blautia	186801|Clostridia	P	Oxaloacetate decarboxylase, gamma chain	-	-	-	-	-	-	-	-	-	-	-	-	OAD_gamma
NFNHFNFO_00415	33035.JPJF01000038_gene483	0.0	903.0	COG4799@1|root,COG4799@2|Bacteria,1TQCV@1239|Firmicutes,247WG@186801|Clostridia,3XZR6@572511|Blautia	186801|Clostridia	I	Acetyl-CoA carboxylase alpha subunit	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
NFNHFNFO_00416	33035.JPJF01000038_gene484	1e-173	486.0	COG0159@1|root,COG0159@2|Bacteria,1TPXA@1239|Firmicutes,248M2@186801|Clostridia,3XYZ4@572511|Blautia	186801|Clostridia	E	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate	trpA	-	4.2.1.20	ko:K01695	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	Trp_syntA
NFNHFNFO_00417	33035.JPJF01000038_gene485	4.16e-279	763.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,3XYNP@572511|Blautia	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NFNHFNFO_00418	33035.JPJF01000038_gene486	6.35e-118	341.0	COG0135@1|root,COG0135@2|Bacteria,1V6Y0@1239|Firmicutes,24HBQ@186801|Clostridia,3Y006@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	trpF	-	5.3.1.24	ko:K01817	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03509	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	PRAI
NFNHFNFO_00419	33035.JPJF01000038_gene487	7.79e-169	474.0	COG0134@1|root,COG0134@2|Bacteria,1TR94@1239|Firmicutes,249ZY@186801|Clostridia,3XYU5@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	trpC	-	4.1.1.48	ko:K01609	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R03508	RC00944	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPS
NFNHFNFO_00420	33035.JPJF01000038_gene488	0.0	1003.0	COG0512@1|root,COG0547@1|root,COG0512@2|Bacteria,COG0547@2|Bacteria,1TP8U@1239|Firmicutes,247WY@186801|Clostridia,3XZ38@572511|Blautia	186801|Clostridia	E	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)	trpD	-	2.4.2.18,4.1.3.27	ko:K00766,ko:K13497	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00023	R00985,R00986,R01073	RC00010,RC00440,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Glycos_trans_3N,Glycos_transf_3
NFNHFNFO_00421	33035.JPJF01000038_gene489	0.0	924.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,3XZB8@572511|Blautia	186801|Clostridia	EH	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia	trpE	-	4.1.3.27	ko:K01657	ko00400,ko00405,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986	RC00010,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	-	Anth_synt_I_N,Chorismate_bind
NFNHFNFO_00422	33035.JPJF01000038_gene491	4.71e-213	600.0	29U5C@1|root,30FEZ@2|Bacteria,1UDYI@1239|Firmicutes,25ISV@186801|Clostridia,3Y263@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00423	33035.JPJF01000038_gene492	1.33e-293	801.0	COG0162@1|root,COG0162@2|Bacteria,1TPGN@1239|Firmicutes,247QC@186801|Clostridia,3XYHR@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)	tyrS	-	6.1.1.1	ko:K01866	ko00970,map00970	M00359,M00360	R02918	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	S4,tRNA-synt_1b
NFNHFNFO_00424	33035.JPJF01000038_gene493	1.54e-270	743.0	COG1251@1|root,COG1251@2|Bacteria,1UKQX@1239|Firmicutes,25E9F@186801|Clostridia,3XZM4@572511|Blautia	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	narC	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2
NFNHFNFO_00425	33035.JPJF01000038_gene494	1.26e-96	281.0	COG1142@1|root,COG1142@2|Bacteria,1V809@1239|Firmicutes,25E9V@186801|Clostridia,3Y27V@572511|Blautia	186801|Clostridia	C	carbon monoxide dehydrogenase, iron sulfur subunit K00196	-	-	-	ko:K00196	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	-	R07157,R08034	RC00250,RC02800	ko00000,ko00001	-	-	-	Fer4_11,Fer4_4
NFNHFNFO_00426	33035.JPJF01000038_gene495	0.0	1230.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,3XYRR@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	cooS	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04490	Prismane
NFNHFNFO_00427	33035.JPJF01000038_gene497	2.7e-307	841.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZ7T@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NFNHFNFO_00428	33035.JPJF01000038_gene498	3.34e-313	860.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3XZAA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
NFNHFNFO_00429	33035.JPJF01000038_gene499	1.57e-282	775.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia,3XZSG@572511|Blautia	186801|Clostridia	S	VWA-like domain (DUF2201)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
NFNHFNFO_00430	33035.JPJF01000038_gene500	3.15e-64	197.0	2C40S@1|root,2ZJHR@2|Bacteria,1W4S9@1239|Firmicutes,254RW@186801|Clostridia,3Y21T@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00431	33035.JPJF01000038_gene501	4.13e-196	545.0	COG2084@1|root,COG2084@2|Bacteria,1TR4F@1239|Firmicutes,249YG@186801|Clostridia,3XZKE@572511|Blautia	186801|Clostridia	I	COG COG2084 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases	garR	-	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	-	NAD_binding_11,NAD_binding_2
NFNHFNFO_00432	33035.JPJF01000038_gene502	7.46e-45	145.0	COG0236@1|root,COG0236@2|Bacteria,1UI0X@1239|Firmicutes,25E9W@186801|Clostridia	186801|Clostridia	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
NFNHFNFO_00433	33035.JPJF01000038_gene503	0.0	975.0	COG1022@1|root,COG1022@2|Bacteria,1V0YG@1239|Firmicutes,25E9H@186801|Clostridia,3XZQH@572511|Blautia	186801|Clostridia	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
NFNHFNFO_00434	33035.JPJF01000038_gene504	0.0	900.0	COG2204@1|root,COG2206@1|root,COG2204@2|Bacteria,COG2206@2|Bacteria,1UZN2@1239|Firmicutes,248SE@186801|Clostridia	186801|Clostridia	T	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF3369,GAF,GAF_2,HAMP,HD,HD_5,PAS_9,Response_reg
NFNHFNFO_00435	33035.JPJF01000038_gene505	0.0	1080.0	COG4191@1|root,COG4191@2|Bacteria,1UZX4@1239|Firmicutes,24B8M@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,HisKA_7TM,dCache_1
NFNHFNFO_00436	33035.JPJF01000038_gene506	0.0	4284.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia,3Y1GF@572511|Blautia	186801|Clostridia	Q	AMP-binding enzyme C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C,Acyltransferase,Condensation,NAD_binding_4,PP-binding
NFNHFNFO_00437	33035.JPJF01000038_gene507	2.35e-156	442.0	COG0010@1|root,COG0010@2|Bacteria,1V6Y2@1239|Firmicutes,24K01@186801|Clostridia,3Y08B@572511|Blautia	186801|Clostridia	E	Belongs to the arginase family	-	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
NFNHFNFO_00438	33035.JPJF01000038_gene508	1.58e-100	291.0	COG0071@1|root,COG0071@2|Bacteria,1VG0E@1239|Firmicutes,24MRZ@186801|Clostridia,3Y04I@572511|Blautia	186801|Clostridia	O	COG COG0071 Molecular chaperone (small heat shock protein)	hsp18	-	-	ko:K13993	ko04141,map04141	-	-	-	ko00000,ko00001,ko03110	-	-	-	HSP20
NFNHFNFO_00439	33035.JPJF01000038_gene509	2.3e-294	805.0	COG1145@1|root,COG1145@2|Bacteria,1TQG5@1239|Firmicutes,248IV@186801|Clostridia,3Y179@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6,Fer4_7
NFNHFNFO_00440	33035.JPJF01000038_gene510	1.15e-108	314.0	COG0778@1|root,COG0778@2|Bacteria,1V4K6@1239|Firmicutes,24B09@186801|Clostridia,3Y0KM@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NFNHFNFO_00441	33035.JPJF01000038_gene511	4.57e-287	785.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3XZ3I@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S11 family	dacB2	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NFNHFNFO_00442	33035.JPJF01000038_gene512	4.2e-284	778.0	COG2270@1|root,COG2270@2|Bacteria,1TRTH@1239|Firmicutes,24AYI@186801|Clostridia,3XYWK@572511|Blautia	186801|Clostridia	S	COG COG2270 Permeases of the major facilitator superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	ATG22
NFNHFNFO_00443	33035.JPJF01000038_gene513	1.32e-179	501.0	COG0770@1|root,COG0770@2|Bacteria,1V1NG@1239|Firmicutes,24GE1@186801|Clostridia,3Y02I@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Zn_dep_PLPC
NFNHFNFO_00444	33035.JPJF01000038_gene514	1.79e-125	358.0	COG1386@1|root,COG1386@2|Bacteria,1V6HI@1239|Firmicutes,24JW7@186801|Clostridia,3XYWQ@572511|Blautia	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves	scpB	-	-	ko:K06024	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpB
NFNHFNFO_00445	33035.JPJF01000038_gene515	8.23e-170	475.0	COG1354@1|root,COG1354@2|Bacteria,1TRW3@1239|Firmicutes,249VW@186801|Clostridia,3XYTH@572511|Blautia	186801|Clostridia	D	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves	scpA	-	-	ko:K05896	-	-	-	-	ko00000,ko03036	-	-	-	SMC_ScpA
NFNHFNFO_00446	33035.JPJF01000038_gene516	5.44e-213	597.0	2DSUF@1|root,33HGC@2|Bacteria,1VK81@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129
NFNHFNFO_00447	33035.JPJF01000038_gene517	2.35e-251	692.0	COG1721@1|root,COG1721@2|Bacteria,1TSYT@1239|Firmicutes,249GJ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
NFNHFNFO_00448	33035.JPJF01000038_gene518	1.25e-211	586.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia,3XYTD@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
NFNHFNFO_00449	33035.JPJF01000038_gene519	2.27e-162	458.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,248PS@186801|Clostridia,3XZYI@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NFNHFNFO_00450	33035.JPJF01000038_gene520	8.81e-289	793.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZQ9@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_00451	33035.JPJF01000038_gene521	2.64e-267	733.0	COG1686@1|root,COG1686@2|Bacteria,1TQN0@1239|Firmicutes,249B3@186801|Clostridia,3XYIQ@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S11 family	dacF	-	3.4.16.4	ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NFNHFNFO_00452	33035.JPJF01000038_gene522	1.31e-99	296.0	2DA7D@1|root,32TUU@2|Bacteria,1VEDT@1239|Firmicutes,24REG@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00453	33035.JPJF01000038_gene524	8.66e-136	384.0	COG4905@1|root,COG4905@2|Bacteria,1V3M8@1239|Firmicutes,24G7Q@186801|Clostridia,3Y1JT@572511|Blautia	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NFNHFNFO_00454	33035.JPJF01000038_gene525	0.0	1015.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3XZ8D@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	-	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
NFNHFNFO_00455	1121115.AXVN01000001_gene1050	3.98e-29	104.0	COG0828@1|root,COG0828@2|Bacteria,1VEHU@1239|Firmicutes,24QP9@186801|Clostridia,3Y0K6@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bS21 family	rpsU	-	-	ko:K02970	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S21
NFNHFNFO_00456	33035.JPJF01000038_gene526	0.0	1640.0	COG0013@1|root,COG0013@2|Bacteria,1TPK6@1239|Firmicutes,248M3@186801|Clostridia,3XYZ6@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain	alaS	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NFNHFNFO_00457	33035.JPJF01000038_gene527	1.46e-111	324.0	COG2364@1|root,COG2364@2|Bacteria,1TU27@1239|Firmicutes,25NE7@186801|Clostridia,3Y0V8@572511|Blautia	186801|Clostridia	S	Membrane	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00458	33035.JPJF01000038_gene528	1.47e-194	542.0	COG2207@1|root,COG2207@2|Bacteria,1UYFB@1239|Firmicutes,24DAW@186801|Clostridia,3Y28A@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NFNHFNFO_00459	1163671.JAGI01000002_gene3962	6.92e-104	308.0	COG2265@1|root,COG2265@2|Bacteria,1UK4G@1239|Firmicutes,24H6A@186801|Clostridia	186801|Clostridia	J	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
NFNHFNFO_00460	33035.JPJF01000038_gene529	1.68e-303	833.0	COG2211@1|root,COG2211@2|Bacteria,1UJ7Q@1239|Firmicutes,24DJ1@186801|Clostridia	186801|Clostridia	G	TIGRFAM sugar (Glycoside-Pentoside-Hexuronide) transporter	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_00463	33035.JPJF01000038_gene530	2.29e-115	330.0	COG0328@1|root,COG0328@2|Bacteria,1V4A0@1239|Firmicutes,24FSS@186801|Clostridia,3XZXB@572511|Blautia	186801|Clostridia	L	RNase H	rnhA	-	3.1.26.4	ko:K03469	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_H
NFNHFNFO_00464	33035.JPJF01000038_gene531	0.0	1026.0	COG0249@1|root,COG0249@2|Bacteria,1TPJP@1239|Firmicutes,247IW@186801|Clostridia,3XZ5A@572511|Blautia	186801|Clostridia	L	DNA mismatch repair protein	mutS2	-	-	-	-	-	-	-	-	-	-	-	MutS_III,MutS_V
NFNHFNFO_00465	33035.JPJF01000038_gene532	3.19e-301	822.0	COG0001@1|root,COG0001@2|Bacteria,1TPNH@1239|Firmicutes,248II@186801|Clostridia,3XZ92@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	hemL	-	5.4.3.8	ko:K01845	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02272	RC00677	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NFNHFNFO_00466	33035.JPJF01000038_gene533	1.56e-231	637.0	COG0113@1|root,COG0113@2|Bacteria,1TP09@1239|Firmicutes,2496V@186801|Clostridia,3XYXB@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	hemB	-	4.2.1.24	ko:K01698	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R00036	RC00918,RC01781	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ALAD
NFNHFNFO_00467	33035.JPJF01000038_gene534	0.0	1486.0	COG0007@1|root,COG0181@1|root,COG1587@1|root,COG0007@2|Bacteria,COG0181@2|Bacteria,COG1587@2|Bacteria,1TQNH@1239|Firmicutes,2487I@186801|Clostridia,3XZE7@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobA	-	1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4	ko:K02302,ko:K02303,ko:K13542	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03165,R03194,R03947	RC00003,RC00871,RC01012,RC01034,RC01861	ko00000,ko00001,ko00002,ko01000	-	-	-	HEM4,Porphobil_deam,Porphobil_deamC,TP_methylase
NFNHFNFO_00468	33035.JPJF01000038_gene535	3.37e-99	289.0	COG1648@1|root,COG1648@2|Bacteria,1VA2E@1239|Firmicutes,24N6M@186801|Clostridia,3Y08Y@572511|Blautia	186801|Clostridia	H	precorrin-2 oxidase	cysG	-	1.3.1.76,4.99.1.4	ko:K02304	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R02864,R03947	RC01012,RC01034	ko00000,ko00001,ko00002,ko01000	-	-	-	CysG_dimeriser,NAD_binding_7,Sirohm_synth_M
NFNHFNFO_00469	33035.JPJF01000038_gene536	8.44e-282	771.0	COG0373@1|root,COG0373@2|Bacteria,1TQN9@1239|Firmicutes,2496M@186801|Clostridia,3XZQJ@572511|Blautia	186801|Clostridia	H	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)	hemA	-	1.2.1.70	ko:K02492	ko00860,ko01100,ko01110,ko01120,map00860,map01100,map01110,map01120	M00121	R04109	RC00055,RC00149	ko00000,ko00001,ko00002,ko01000	-	-	-	GlutR_N,GlutR_dimer,NAD_binding_7,Shikimate_DH
NFNHFNFO_00470	33035.JPJF01000038_gene537	7.07e-168	470.0	COG0310@1|root,COG0310@2|Bacteria,1TQVK@1239|Firmicutes,248ZZ@186801|Clostridia,3XYU1@572511|Blautia	186801|Clostridia	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiM	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM
NFNHFNFO_00471	33035.JPJF01000038_gene538	1.25e-57	179.0	COG1930@1|root,COG1930@2|Bacteria,1VF03@1239|Firmicutes,24MYG@186801|Clostridia,3Y0GQ@572511|Blautia	186801|Clostridia	P	Part of the energy-coupling factor (ECF) transporter complex CbiMNOQ involved in cobalt import	cbiN	-	-	ko:K02009	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18	-	-	CbiN
NFNHFNFO_00472	33035.JPJF01000038_gene539	6.47e-169	473.0	COG0619@1|root,COG0619@2|Bacteria,1V0B0@1239|Firmicutes,24A4J@186801|Clostridia,3XYVF@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
NFNHFNFO_00473	33035.JPJF01000038_gene540	0.0	1055.0	COG1122@1|root,COG4822@1|root,COG1122@2|Bacteria,COG4822@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3XYPV@572511|Blautia	186801|Clostridia	P	ABC transporter, ATP-binding protein	cbiO	-	-	ko:K02006	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	ABC_tran
NFNHFNFO_00474	33035.JPJF01000038_gene541	2.79e-138	419.0	COG2304@1|root,COG2304@2|Bacteria,1TXAR@1239|Firmicutes,25AE5@186801|Clostridia,3Y1EI@572511|Blautia	186801|Clostridia	S	oxidoreductase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00475	33035.JPJF01000038_gene542	1.28e-145	411.0	COG2082@1|root,COG2082@2|Bacteria,1V1SX@1239|Firmicutes,24B9Z@186801|Clostridia,3XZ03@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobH	-	5.4.99.60,5.4.99.61	ko:K06042	ko00860,ko01100,map00860,map01100	-	R05177,R05814	RC01292,RC01980	ko00000,ko00001,ko01000	-	-	-	CbiC
NFNHFNFO_00476	33035.JPJF01000038_gene543	0.0	914.0	COG1492@1|root,COG1492@2|Bacteria,1TP5E@1239|Firmicutes,248XW@186801|Clostridia,3XYMB@572511|Blautia	186801|Clostridia	H	Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation	cobQ	-	6.3.5.10	ko:K02232	ko00860,ko01100,map00860,map01100	M00122	R05225	RC00010,RC01302	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS15780	AAA_26,CbiA,GATase_3
NFNHFNFO_00477	33035.JPJF01000038_gene544	7.61e-215	597.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,3XYPR@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	cobD_2	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
NFNHFNFO_00478	33035.JPJF01000038_gene545	6.83e-208	577.0	COG1270@1|root,COG1270@2|Bacteria,1TQ3X@1239|Firmicutes,247PR@186801|Clostridia,3XZ9X@572511|Blautia	186801|Clostridia	H	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group	cobD	-	6.3.1.10	ko:K02227	ko00860,ko01100,map00860,map01100	M00122	R06529,R07302	RC00090,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	CobD_Cbib
NFNHFNFO_00479	33035.JPJF01000038_gene546	6.29e-127	363.0	COG0406@1|root,COG0406@2|Bacteria,1V6G1@1239|Firmicutes,24JP4@186801|Clostridia,3XZUY@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	cobC	-	3.1.3.73	ko:K02226	ko00860,ko01100,map00860,map01100	M00122	R04594,R11173	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	His_Phos_1
NFNHFNFO_00480	33035.JPJF01000038_gene547	3.83e-71	216.0	COG2087@1|root,COG2087@2|Bacteria,1VG8S@1239|Firmicutes,24QSM@186801|Clostridia,3Y0HX@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	CobU
NFNHFNFO_00481	33035.JPJF01000038_gene548	3.49e-175	489.0	COG0368@1|root,COG0368@2|Bacteria,1V1QB@1239|Firmicutes,24I0D@186801|Clostridia,3Y00I@572511|Blautia	186801|Clostridia	H	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate	cobS	-	2.7.8.26	ko:K02233	ko00860,ko01100,map00860,map01100	M00122	R05223,R11174	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CobS
NFNHFNFO_00482	33035.JPJF01000038_gene549	1.46e-114	330.0	COG2087@1|root,COG2087@2|Bacteria,1V6F8@1239|Firmicutes,24JF6@186801|Clostridia,3Y004@572511|Blautia	186801|Clostridia	H	COG COG2087 Adenosyl cobinamide kinase adenosyl cobinamide phosphate guanylyltransferase	cobU	-	2.7.1.156,2.7.7.62	ko:K02231	ko00860,ko01100,map00860,map01100	M00122	R05221,R05222,R06558	RC00002,RC00428	ko00000,ko00001,ko00002,ko01000	-	-	-	CobU
NFNHFNFO_00483	33035.JPJF01000038_gene550	1.7e-237	654.0	COG2038@1|root,COG2038@2|Bacteria,1TPC1@1239|Firmicutes,25DH5@186801|Clostridia,3XYHW@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB)	cobT	-	2.4.2.21	ko:K00768	ko00860,ko01100,map00860,map01100	M00122	R04148	RC00033,RC00063	ko00000,ko00001,ko00002,ko01000	-	-	-	DBI_PRT
NFNHFNFO_00484	33035.JPJF01000038_gene551	0.0	879.0	COG1797@1|root,COG1797@2|Bacteria,1TNY2@1239|Firmicutes,247PU@186801|Clostridia,3XYMG@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source	cbiA	-	6.3.5.11,6.3.5.9	ko:K02224	ko00860,ko01100,ko01120,map00860,map01100,map01120	-	R05224,R05815	RC00010,RC01301	ko00000,ko00001,ko01000	-	-	-	AAA_26,CbiA,GATase_3
NFNHFNFO_00485	33035.JPJF01000038_gene552	0.0	1182.0	COG2099@1|root,COG2241@1|root,COG2242@1|root,COG2099@2|Bacteria,COG2241@2|Bacteria,COG2242@2|Bacteria,1TS3H@1239|Firmicutes,2483G@186801|Clostridia,3XYK0@572511|Blautia	186801|Clostridia	H	precorrin-6B methylase decarboxylase cbiT cbiE	cbiT	-	2.1.1.132,2.1.1.196	ko:K00595,ko:K02191	ko00860,ko01100,map00860,map01100	-	R05149,R05813,R07774	RC00003,RC01279,RC02052,RC02054	ko00000,ko00001,ko01000	-	-	-	CbiJ,Cons_hypoth95,MTS,Met_10,Methyltransf_31,Methyltransf_4,PCMT,TP_methylase
NFNHFNFO_00486	33035.JPJF01000038_gene553	1.5e-171	479.0	COG1010@1|root,COG1010@2|Bacteria,1TPJ7@1239|Firmicutes,247QS@186801|Clostridia,3XZR9@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobJ	-	2.1.1.131,2.1.1.272	ko:K05934,ko:K21479	ko00860,ko01100,map00860,map01100	-	R05180,R05809,R11580	RC00003,RC01293,RC03471,RC03479	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NFNHFNFO_00487	33035.JPJF01000038_gene554	1.03e-261	717.0	COG2073@1|root,COG2073@2|Bacteria,1TPYM@1239|Firmicutes,247JW@186801|Clostridia,3XZ11@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cbiG	-	3.7.1.12	ko:K02189	ko00860,ko01100,map00860,map01100	-	R07772	RC01545,RC02097	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS15705	CbiG_C,CbiG_N,CbiG_mid
NFNHFNFO_00488	33035.JPJF01000038_gene555	8.95e-174	485.0	COG2875@1|root,COG2875@2|Bacteria,1TP6J@1239|Firmicutes,248IZ@186801|Clostridia,3XYRB@572511|Blautia	186801|Clostridia	H	precorrin-4 C11-methyltransferase	cobM	-	2.1.1.133,2.1.1.271	ko:K05936	ko00860,ko01100,map00860,map01100	-	R05181,R05810	RC00003,RC01294,RC02049	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NFNHFNFO_00489	33035.JPJF01000038_gene556	1.31e-151	427.0	COG2243@1|root,COG2243@2|Bacteria,1TP87@1239|Firmicutes,249DM@186801|Clostridia,3XYXX@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cobI	-	2.1.1.130,2.1.1.151	ko:K03394	ko00860,ko01100,map00860,map01100	-	R03948,R05808	RC00003,RC01035,RC01662	ko00000,ko00001,ko01000	-	-	-	TP_methylase
NFNHFNFO_00490	33035.JPJF01000038_gene557	9.74e-256	704.0	COG1903@1|root,COG1903@2|Bacteria,1TQ3M@1239|Firmicutes,248AK@186801|Clostridia,3XYN5@572511|Blautia	186801|Clostridia	H	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A	cbiD	-	2.1.1.195	ko:K02188	ko00860,ko01100,map00860,map01100	-	R07773	RC00003,RC02051	ko00000,ko00001,ko01000	-	-	-	CbiD
NFNHFNFO_00491	33035.JPJF01000038_gene558	0.0	945.0	COG0699@1|root,COG0699@2|Bacteria,1TPPG@1239|Firmicutes,24829@186801|Clostridia,3XZK9@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	spoIVA	GO:0000003,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0008144,GO:0008150,GO:0009653,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019954,GO:0030154,GO:0030312,GO:0030435,GO:0030436,GO:0030554,GO:0031160,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0034301,GO:0035639,GO:0036094,GO:0042601,GO:0042763,GO:0043167,GO:0043168,GO:0043934,GO:0043936,GO:0044464,GO:0048646,GO:0048856,GO:0048869,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363	-	ko:K06398	-	-	-	-	ko00000	-	-	-	Spore_IV_A
NFNHFNFO_00492	33035.JPJF01000038_gene559	0.0	888.0	COG4277@1|root,COG4277@2|Bacteria,1TRT2@1239|Firmicutes,247UD@186801|Clostridia,3XZAW@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HHH_3,Radical_SAM
NFNHFNFO_00493	33035.JPJF01000038_gene560	3.52e-174	486.0	2DBGV@1|root,2Z969@2|Bacteria,1UI0Y@1239|Firmicutes,25E9X@186801|Clostridia,3XZRX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4130
NFNHFNFO_00494	33035.JPJF01000038_gene561	3.17e-169	475.0	COG1180@1|root,COG1180@2|Bacteria,1TP46@1239|Firmicutes,248K9@186801|Clostridia	186801|Clostridia	C	PFAM Radical SAM	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NFNHFNFO_00495	33035.JPJF01000038_gene562	2.91e-279	770.0	COG2078@1|root,COG3885@1|root,COG2078@2|Bacteria,COG3885@2|Bacteria,1TQH8@1239|Firmicutes,2491Q@186801|Clostridia	186801|Clostridia	S	Extradiol ring-cleavage dioxygenase class III protein subunit B	-	-	-	ko:K06990,ko:K09141	-	-	-	-	ko00000,ko04812	-	-	-	AMMECR1,LigB
NFNHFNFO_00496	33035.JPJF01000038_gene563	3.48e-316	864.0	COG1502@1|root,COG1502@2|Bacteria,1TSN8@1239|Firmicutes,249G7@186801|Clostridia,3XYPQ@572511|Blautia	186801|Clostridia	M	COG COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes	-	-	-	ko:K06132	ko00564,ko01100,map00564,map01100	-	R11062	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2
NFNHFNFO_00497	33035.JPJF01000038_gene564	1.24e-199	553.0	COG0190@1|root,COG0190@2|Bacteria,1TP1P@1239|Firmicutes,248DB@186801|Clostridia,3XZ53@572511|Blautia	186801|Clostridia	H	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate	folD	-	1.5.1.5,3.5.4.9	ko:K01491	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R01220,R01655	RC00202,RC00578	ko00000,ko00001,ko00002,ko01000	-	-	-	THF_DHG_CYH,THF_DHG_CYH_C
NFNHFNFO_00498	33035.JPJF01000038_gene565	6.09e-136	386.0	COG3404@1|root,COG3404@2|Bacteria,1V14R@1239|Firmicutes,24D90@186801|Clostridia,3XYUI@572511|Blautia	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	-	-	-	-	-	-	-	-	-	-	FTCD_C
NFNHFNFO_00499	33035.JPJF01000038_gene566	2.59e-125	357.0	COG3275@1|root,COG3275@2|Bacteria,1TTD7@1239|Firmicutes,25MGI@186801|Clostridia,3Y1YW@572511|Blautia	186801|Clostridia	T	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00500	33035.JPJF01000038_gene567	7.19e-154	432.0	2C5Z2@1|root,32A20@2|Bacteria,1V5CS@1239|Firmicutes,24M7C@186801|Clostridia,3XZ4M@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
NFNHFNFO_00501	33035.JPJF01000038_gene568	0.0	1254.0	COG1018@1|root,COG3894@1|root,COG1018@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,3XYV5@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
NFNHFNFO_00502	33035.JPJF01000038_gene569	3.41e-186	517.0	COG1410@1|root,COG1410@2|Bacteria,1UXXG@1239|Firmicutes,24D45@186801|Clostridia,3XZQ5@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	acsE	-	2.1.1.258	ko:K15023	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R02289,R10243	RC00004,RC00113,RC01144,RC02871,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
NFNHFNFO_00503	33035.JPJF01000038_gene570	3.38e-297	813.0	COG1456@1|root,COG1456@2|Bacteria,1TPWJ@1239|Firmicutes,24CTU@186801|Clostridia,3XZ0J@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	acsC	-	2.1.1.245	ko:K00197	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD,FeS
NFNHFNFO_00504	33035.JPJF01000038_gene571	1.41e-215	596.0	COG2069@1|root,COG2069@2|Bacteria,1TSSY@1239|Firmicutes,24BVJ@186801|Clostridia,3XZ3W@572511|Blautia	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase delta subunit	acsD	-	2.1.1.245	ko:K00194	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00357,M00377,M00422	R09096,R10219,R10243	RC00004,RC00113,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhD
NFNHFNFO_00505	537007.BLAHAN_05772	0.0	1328.0	COG1614@1|root,COG1614@2|Bacteria,1TSWZ@1239|Firmicutes,248Y2@186801|Clostridia,3XZDK@572511|Blautia	186801|Clostridia	C	acetyl-CoA decarbonylase synthase complex subunit beta	cdhC	-	2.3.1.169	ko:K14138	ko00720,ko01120,ko01200,map00720,map01120,map01200	M00377	R08433,R10243	RC00004,RC00113,RC01144,RC02963,RC02964,RC02977	ko00000,ko00001,ko00002,ko01000	-	-	-	CdhC
NFNHFNFO_00506	33035.JPJF01000060_gene2429	3.14e-179	499.0	COG3640@1|root,COG3640@2|Bacteria,1TPCY@1239|Firmicutes,247JM@186801|Clostridia,3XZK1@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	cooC	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	CbiA
NFNHFNFO_00507	33035.JPJF01000060_gene2428	0.0	1256.0	COG0369@1|root,COG1151@2|Bacteria,1TRSC@1239|Firmicutes,248HQ@186801|Clostridia,3XZEI@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	cooS1	-	1.2.7.4	ko:K00198	ko00633,ko00680,ko00720,ko01120,ko01200,map00633,map00680,map00720,map01120,map01200	M00377	R07157,R08034	RC00250,RC02800	ko00000,ko00001,ko00002,ko01000	-	-	-	Prismane
NFNHFNFO_00508	33035.JPJF01000060_gene2427	3.96e-178	496.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,3XYPW@572511|Blautia	186801|Clostridia	D	cell division inhibitor, membrane ATPase MinD	cooC1	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	AAA_31,CbiA
NFNHFNFO_00509	33035.JPJF01000060_gene2426	1.15e-225	620.0	COG0685@1|root,COG0685@2|Bacteria,1TQFE@1239|Firmicutes,247ZK@186801|Clostridia,3Y08F@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	metF	-	1.5.1.20	ko:K00297	ko00670,ko00720,ko01100,ko01120,ko01200,ko01523,map00670,map00720,map01100,map01120,map01200,map01523	M00377	R01224,R07168	RC00081	ko00000,ko00001,ko00002,ko01000	-	-	-	MTHFR
NFNHFNFO_00510	33035.JPJF01000060_gene2425	2.42e-33	115.0	2FK7C@1|root,34BV3@2|Bacteria,1W6KA@1239|Firmicutes,254TZ@186801|Clostridia,3Y0MF@572511|Blautia	186801|Clostridia	S	Predicted RNA-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	RNA_bind_2
NFNHFNFO_00511	33035.JPJF01000060_gene2424	8.54e-67	203.0	2CEVS@1|root,32WBX@2|Bacteria,1VBHQ@1239|Firmicutes,24QCM@186801|Clostridia,3Y0BP@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00512	33035.JPJF01000013_gene4724	0.0	2194.0	COG1196@1|root,COG2931@1|root,COG1196@2|Bacteria,COG2931@2|Bacteria,1UI05@1239|Firmicutes	1239|Firmicutes	Q	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00513	33035.JPJF01000013_gene4725	1.9e-266	734.0	COG1388@1|root,COG3858@1|root,COG1388@2|Bacteria,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia,3XYVZ@572511|Blautia	186801|Clostridia	M	Glycosyl hydrolases family 18	-	-	-	ko:K06306	-	-	-	-	ko00000	-	-	-	Glyco_hydro_18,LysM
NFNHFNFO_00514	33035.JPJF01000013_gene4726	1.63e-31	112.0	2DTB6@1|root,33JI0@2|Bacteria,1VQRZ@1239|Firmicutes,24X41@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00515	33035.JPJF01000010_gene1264	2.33e-171	482.0	COG4974@1|root,COG4974@2|Bacteria,1TY7M@1239|Firmicutes,24BN9@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
NFNHFNFO_00516	33035.JPJF01000010_gene1263	1.65e-152	430.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24DB9@186801|Clostridia,3Y0I2@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NFNHFNFO_00517	33035.JPJF01000010_gene1262	1.71e-221	639.0	2DQRX@1|root,338BJ@2|Bacteria,1VI3G@1239|Firmicutes,24SAD@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00518	33035.JPJF01000010_gene1261	0.0	1003.0	COG3290@1|root,COG5002@1|root,COG3290@2|Bacteria,COG5002@2|Bacteria,1VC62@1239|Firmicutes,25E8N@186801|Clostridia,3Y0QU@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NFNHFNFO_00519	33035.JPJF01000010_gene1255	6.59e-160	448.0	COG0081@1|root,COG0081@2|Bacteria,1TPTS@1239|Firmicutes,247JB@186801|Clostridia,3XZIY@572511|Blautia	186801|Clostridia	J	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release	rplA	-	-	ko:K02863	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L1
NFNHFNFO_00520	33035.JPJF01000010_gene1254	5.65e-92	269.0	COG0080@1|root,COG0080@2|Bacteria,1V1BS@1239|Firmicutes,24FSQ@186801|Clostridia,3XZUC@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors	rplK	-	-	ko:K02867	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L11,Ribosomal_L11_N
NFNHFNFO_00521	33035.JPJF01000010_gene1253	2.73e-118	338.0	COG0250@1|root,COG0250@2|Bacteria,1TR3P@1239|Firmicutes,248XB@186801|Clostridia,3XZ8Y@572511|Blautia	186801|Clostridia	K	Participates in transcription elongation, termination and antitermination	nusG	-	-	ko:K02601	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KOW,NusG
NFNHFNFO_00522	33035.JPJF01000010_gene1252	2.86e-35	120.0	COG0690@1|root,COG0690@2|Bacteria,1VH7Y@1239|Firmicutes,24RJ1@186801|Clostridia,3Y0SS@572511|Blautia	186801|Clostridia	U	SecE/Sec61-gamma subunits of protein translocation complex	secE	-	-	ko:K03073	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecE
NFNHFNFO_00523	1552123.EP57_12330	1.91e-128	372.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,4HBKE@91061|Bacilli,26KR6@186820|Listeriaceae	91061|Bacilli	G	ABC transporter (permease)	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_00524	1121115.AXVN01000014_gene1228	9.69e-28	115.0	COG0491@1|root,COG0491@2|Bacteria,1V3ZB@1239|Firmicutes,25BG4@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
NFNHFNFO_00525	1449338.JQLU01000005_gene1503	1.67e-135	392.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,4HBEF@91061|Bacilli,27FZI@186828|Carnobacteriaceae	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_00526	1449338.JQLU01000005_gene1504	6.47e-163	471.0	COG1653@1|root,COG1653@2|Bacteria,1UWS1@1239|Firmicutes,4I336@91061|Bacilli,27HT9@186828|Carnobacteriaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00527	658086.HMPREF0994_06015	1.17e-63	207.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes	1239|Firmicutes	K	AraC family	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_00528	33035.JPJF01000010_gene1251	1.22e-54	172.0	COG4828@1|root,COG4828@2|Bacteria,1VACG@1239|Firmicutes,24JWS@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1622)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1622
NFNHFNFO_00529	33035.JPJF01000010_gene1250	1.83e-179	511.0	COG1994@1|root,COG1994@2|Bacteria,1V3Y3@1239|Firmicutes,24C6G@186801|Clostridia	186801|Clostridia	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
NFNHFNFO_00530	457421.CBFG_01650	9.11e-41	142.0	COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,249W3@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
NFNHFNFO_00531	33035.JPJF01000010_gene1249	2.03e-127	364.0	COG1309@1|root,COG1309@2|Bacteria,1V1ZJ@1239|Firmicutes,24FQ3@186801|Clostridia,3Y20D@572511|Blautia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_00532	33035.JPJF01000010_gene1248	3.73e-216	603.0	COG0535@1|root,COG0535@2|Bacteria,1TR52@1239|Firmicutes,247SB@186801|Clostridia,3XZGW@572511|Blautia	186801|Clostridia	C	Radical SAM superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NFNHFNFO_00533	33035.JPJF01000010_gene1245	1.25e-226	638.0	COG1073@1|root,COG1073@2|Bacteria,1TSFY@1239|Firmicutes,24ETS@186801|Clostridia	186801|Clostridia	M	COG1073 Hydrolases of the alpha beta superfamily	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	CW_binding_2,Cu_amine_oxidN1,DLH,DUF3887,Hydrolase_4,Peptidase_S9
NFNHFNFO_00534	33035.JPJF01000010_gene1244	0.0	910.0	COG2723@1|root,COG2723@2|Bacteria,1TP19@1239|Firmicutes,2485V@186801|Clostridia,3Y00Y@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.21	ko:K05350	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_1,PMI_typeI
NFNHFNFO_00535	33035.JPJF01000010_gene1243	7.39e-189	525.0	COG1082@1|root,COG1082@2|Bacteria,1V08R@1239|Firmicutes,24C9W@186801|Clostridia	186801|Clostridia	G	PFAM Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NFNHFNFO_00536	33035.JPJF01000010_gene1242	1.56e-112	322.0	COG0346@1|root,COG0346@2|Bacteria,1V5GM@1239|Firmicutes,24GNP@186801|Clostridia	186801|Clostridia	E	PFAM Glyoxalase bleomycin resistance protein dioxygenase	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
NFNHFNFO_00537	33035.JPJF01000010_gene1241	2.31e-259	712.0	COG0673@1|root,COG0673@2|Bacteria,1U4A4@1239|Firmicutes,249UF@186801|Clostridia	186801|Clostridia	E	PFAM oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NFNHFNFO_00538	33035.JPJF01000010_gene1240	5.6e-147	417.0	COG4221@1|root,COG4221@2|Bacteria,1UHZY@1239|Firmicutes,24P08@186801|Clostridia	186801|Clostridia	S	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short
NFNHFNFO_00539	33035.JPJF01000010_gene1239	2.14e-201	558.0	COG1175@1|root,COG1175@2|Bacteria,1V180@1239|Firmicutes,25C4R@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_00540	33035.JPJF01000010_gene1238	4.2e-183	511.0	COG0395@1|root,COG0395@2|Bacteria,1TSAB@1239|Firmicutes,249PI@186801|Clostridia,3Y0AX@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_00541	33035.JPJF01000010_gene1237	3.21e-302	829.0	COG2182@1|root,COG2182@2|Bacteria,1TT4I@1239|Firmicutes,249TR@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
NFNHFNFO_00542	33035.JPJF01000010_gene1236	8.49e-105	302.0	COG0346@1|root,COG0346@2|Bacteria,1V5GM@1239|Firmicutes,24RNN@186801|Clostridia	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
NFNHFNFO_00543	33035.JPJF01000010_gene1235	1.49e-193	538.0	COG2207@1|root,COG2207@2|Bacteria,1V293@1239|Firmicutes	1239|Firmicutes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_00544	33035.JPJF01000014_gene4727	5.68e-297	811.0	COG0624@1|root,COG0624@2|Bacteria,1UY58@1239|Firmicutes,24FFH@186801|Clostridia,3Y1CB@572511|Blautia	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
NFNHFNFO_00545	33035.JPJF01000014_gene4728	3.22e-227	626.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3XZ61@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NFNHFNFO_00546	33035.JPJF01000014_gene4729	1.12e-246	677.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3XZ1P@572511|Blautia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NFNHFNFO_00547	33035.JPJF01000014_gene4730	3.3e-280	766.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,2492H@186801|Clostridia,3XZGT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
NFNHFNFO_00548	33035.JPJF01000014_gene4731	7.84e-191	532.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZYG@572511|Blautia	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
NFNHFNFO_00549	33035.JPJF01000014_gene4732	4.76e-205	569.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3Y02S@572511|Blautia	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NFNHFNFO_00550	33035.JPJF01000014_gene4733	0.0	1062.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3Y0CE@572511|Blautia	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NFNHFNFO_00551	33035.JPJF01000014_gene4734	7.18e-208	576.0	arCOG05881@1|root,2Z800@2|Bacteria,1TS9C@1239|Firmicutes,24CDW@186801|Clostridia,3XZMR@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1177
NFNHFNFO_00552	33035.JPJF01000014_gene4735	1.19e-145	413.0	COG4126@1|root,COG4126@2|Bacteria,1TT35@1239|Firmicutes,24KAI@186801|Clostridia,3Y0DR@572511|Blautia	186801|Clostridia	E	AroM protein	-	-	-	ko:K14591	-	-	-	-	ko00000	-	-	-	AroM
NFNHFNFO_00553	33035.JPJF01000014_gene4736	6.79e-263	721.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia	186801|Clostridia	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
NFNHFNFO_00555	33035.JPJF01000014_gene4738	1.05e-309	845.0	COG1807@1|root,COG1807@2|Bacteria,1V22V@1239|Firmicutes,24GKH@186801|Clostridia,3XYRT@572511|Blautia	186801|Clostridia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	PMT_2
NFNHFNFO_00556	33035.JPJF01000014_gene4740	1.53e-178	499.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UUUQ@1239|Firmicutes,25KCM@186801|Clostridia,3Y1UF@572511|Blautia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2,HTH_18
NFNHFNFO_00558	33035.JPJF01000014_gene4742	0.0	1279.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,3Y0XZ@572511|Blautia	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NFNHFNFO_00559	658086.HMPREF0994_04256	9.67e-175	493.0	COG2227@1|root,COG2227@2|Bacteria,1URRF@1239|Firmicutes,259NG@186801|Clostridia,27K42@186928|unclassified Lachnospiraceae	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
NFNHFNFO_00560	1280682.AUKA01000001_gene1844	3.79e-150	440.0	COG2207@1|root,COG2334@1|root,COG2207@2|Bacteria,COG2334@2|Bacteria,1TQGC@1239|Firmicutes,24B49@186801|Clostridia,4BYPK@830|Butyrivibrio	186801|Clostridia	K	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH,HTH_18
NFNHFNFO_00561	397288.C806_02081	4.94e-40	134.0	2AD7W@1|root,32RT8@2|Bacteria,1VCXF@1239|Firmicutes,24JRE@186801|Clostridia,27NWI@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00562	1235802.C823_05739	1.9e-28	113.0	COG0507@1|root,COG1196@1|root,COG0507@2|Bacteria,COG1196@2|Bacteria,1TPU3@1239|Firmicutes,248HY@186801|Clostridia,25W66@186806|Eubacteriaceae	186801|Clostridia	D	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NFNHFNFO_00563	243161.TC_0753	6.3e-10	62.8	COG2204@1|root,COG2204@2|Bacteria,2JFQI@204428|Chlamydiae	204428|Chlamydiae	T	Sigma-54 dependent response regulator	atoC	-	-	ko:K07714	ko02020,map02020	M00500	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_8,Response_reg,Sigma54_activat
NFNHFNFO_00564	411459.RUMOBE_02511	1.06e-223	628.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,3Y01W@572511|Blautia	186801|Clostridia	T	subtilin biosynthesis sensor protein SpaK	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
NFNHFNFO_00565	411469.EUBHAL_01613	8.13e-152	431.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,25VYC@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00566	33035.JPJF01000014_gene4825	7.8e-34	120.0	2DBZU@1|root,2ZC3G@2|Bacteria,1V3AH@1239|Firmicutes,24FZG@186801|Clostridia	186801|Clostridia	S	YodL-like	-	-	-	-	-	-	-	-	-	-	-	-	YodL
NFNHFNFO_00567	1123075.AUDP01000023_gene2863	6.86e-98	284.0	2BKZP@1|root,32FGF@2|Bacteria,1V8BI@1239|Firmicutes,24JQ0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4262
NFNHFNFO_00568	1235792.C808_02179	5.57e-143	408.0	COG0286@1|root,COG0286@2|Bacteria,1UZ8G@1239|Firmicutes,25AWH@186801|Clostridia	186801|Clostridia	V	site-specific DNA-methyltransferase (adenine-specific) activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00569	1123075.AUDP01000023_gene2853	2.34e-71	216.0	29U9F@1|root,2ZY8Y@2|Bacteria,1V67Q@1239|Firmicutes,24HUV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00570	457421.CBFG_05525	8.75e-130	372.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_00571	457421.CBFG_05526	0.0	1189.0	COG0577@1|root,COG0577@2|Bacteria,1TRE5@1239|Firmicutes,24CGY@186801|Clostridia	186801|Clostridia	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NFNHFNFO_00572	658086.HMPREF0994_05963	6.71e-55	175.0	COG3976@1|root,COG3976@2|Bacteria	2|Bacteria	S	FMN binding	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind
NFNHFNFO_00573	457421.CBFG_05527	9.6e-218	613.0	COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,24AAW@186801|Clostridia,26A1A@186813|unclassified Clostridiales	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_00574	457421.CBFG_05529	4.32e-144	409.0	COG0745@1|root,COG0745@2|Bacteria,1TPRM@1239|Firmicutes,25B4D@186801|Clostridia,26B27@186813|unclassified Clostridiales	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00575	478749.BRYFOR_05727	3.19e-188	535.0	COG1373@1|root,COG1373@2|Bacteria,1TP7X@1239|Firmicutes,249UX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_14,DUF4143
NFNHFNFO_00576	1235792.C808_02170	2.77e-156	441.0	COG4509@1|root,COG4509@2|Bacteria,1TRWN@1239|Firmicutes,24JWH@186801|Clostridia,27NJ4@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Sortase family	-	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NFNHFNFO_00577	1235790.C805_03673	1.39e-149	426.0	COG4974@1|root,COG4974@2|Bacteria,1UXIU@1239|Firmicutes,25MA6@186801|Clostridia,25Z8M@186806|Eubacteriaceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_4,Phage_integrase
NFNHFNFO_00578	1123075.AUDP01000023_gene2849	2.27e-31	110.0	COG2909@1|root,COG2909@2|Bacteria,1VEQQ@1239|Firmicutes,24RGN@186801|Clostridia,3WRQZ@541000|Ruminococcaceae	186801|Clostridia	K	trisaccharide binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00579	397291.C804_05878	1.44e-42	153.0	COG2865@1|root,COG2865@2|Bacteria,1TQIP@1239|Firmicutes,24CJ9@186801|Clostridia,27KEF@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
NFNHFNFO_00580	397291.C804_05878	1.77e-150	438.0	COG2865@1|root,COG2865@2|Bacteria,1TQIP@1239|Firmicutes,24CJ9@186801|Clostridia,27KEF@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4
NFNHFNFO_00581	33035.JPJF01000014_gene4843	1.91e-130	371.0	28JGF@1|root,2Z9A7@2|Bacteria,1V13B@1239|Firmicutes,249IA@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_00584	1235798.C817_03843	1.96e-87	259.0	COG0745@1|root,COG0745@2|Bacteria,1V2PY@1239|Firmicutes,24H17@186801|Clostridia	186801|Clostridia	KT	Transcriptional regulatory protein, C-terminal domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Trans_reg_C
NFNHFNFO_00585	397291.C804_02561	5.18e-121	355.0	COG2378@1|root,COG2378@2|Bacteria,1TS78@1239|Firmicutes,25C7I@186801|Clostridia,27IUM@186928|unclassified Lachnospiraceae	186801|Clostridia	K	DeoR-like helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
NFNHFNFO_00586	1235798.C817_05564	3.36e-47	170.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FtsX,MacB_PCD
NFNHFNFO_00587	411460.RUMTOR_01913	2.28e-159	447.0	COG3910@1|root,COG3910@2|Bacteria,1TSWP@1239|Firmicutes,249W3@186801|Clostridia,3Y0TW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21,AAA_23
NFNHFNFO_00588	742735.HMPREF9467_03153	1.27e-30	108.0	2DIMN@1|root,303NN@2|Bacteria,1TUX8@1239|Firmicutes,25I11@186801|Clostridia,223GZ@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00589	1321372.AQQB01000003_gene1483	1.09e-309	847.0	COG1996@1|root,COG1996@2|Bacteria,1UZSK@1239|Firmicutes,4HVI6@91061|Bacilli	91061|Bacilli	K	Probable Zinc-ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF4379
NFNHFNFO_00590	411462.DORLON_00872	2.14e-201	558.0	COG0789@1|root,COG0789@2|Bacteria,1TTZV@1239|Firmicutes,248GR@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NFNHFNFO_00591	537007.BLAHAN_06008	0.0	1105.0	COG1190@1|root,COG1190@2|Bacteria,1TP2P@1239|Firmicutes,247VX@186801|Clostridia,3XZC3@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	lysS	-	6.1.1.6	ko:K04567	ko00970,map00970	M00359,M00360	R03658	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon,tRNA_bind
NFNHFNFO_00592	33035.JPJF01000020_gene3428	5.57e-99	288.0	COG0782@1|root,COG0782@2|Bacteria,1V44S@1239|Firmicutes,24HP9@186801|Clostridia,3XZTG@572511|Blautia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
NFNHFNFO_00593	33035.JPJF01000020_gene3427	5.3e-214	592.0	COG0042@1|root,COG0042@2|Bacteria,1TQ2R@1239|Firmicutes,248HD@186801|Clostridia,3XZC5@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	dus	-	-	ko:K05540	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Dus
NFNHFNFO_00594	33035.JPJF01000020_gene3426	1.43e-177	495.0	COG1521@1|root,COG1521@2|Bacteria,1TR0X@1239|Firmicutes,248PX@186801|Clostridia,3XZ5H@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis	coaX	-	2.7.1.33	ko:K03525	ko00770,ko01100,map00770,map01100	M00120	R02971,R03018,R04391	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	Pan_kinase
NFNHFNFO_00595	33035.JPJF01000020_gene3425	2.59e-68	207.0	2CJXG@1|root,32SB0@2|Bacteria,1VAFJ@1239|Firmicutes,24MNI@186801|Clostridia,3Y06J@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00596	33035.JPJF01000076_gene5076	3.4e-159	449.0	COG0340@1|root,COG0340@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3XZNZ@572511|Blautia	186801|Clostridia	H	Biotin-- acetyl-CoA-carboxylase ligase	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
NFNHFNFO_00597	33035.JPJF01000076_gene5075	3.03e-230	634.0	COG0078@1|root,COG0078@2|Bacteria,1TPF2@1239|Firmicutes,248I5@186801|Clostridia,3XYMZ@572511|Blautia	186801|Clostridia	E	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline	argF	-	2.1.3.3	ko:K00611	ko00220,ko01100,ko01110,ko01130,ko01230,map00220,map01100,map01110,map01130,map01230	M00029,M00844	R01398	RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N
NFNHFNFO_00598	33035.JPJF01000076_gene5074	2.45e-269	738.0	COG1752@1|root,COG1752@2|Bacteria,1UBYN@1239|Firmicutes,247V3@186801|Clostridia,3XZ6Q@572511|Blautia	186801|Clostridia	S	Patatin-like phospholipase	-	-	-	ko:K07001	-	-	-	-	ko00000	-	-	-	Patatin
NFNHFNFO_00599	33035.JPJF01000076_gene5073	2.18e-140	405.0	COG0330@1|root,COG0330@2|Bacteria,1TPXU@1239|Firmicutes,248MP@186801|Clostridia,3XZEQ@572511|Blautia	186801|Clostridia	O	SPFH Band 7 PHB domain protein	qmcA	-	-	-	-	-	-	-	-	-	-	-	Band_7
NFNHFNFO_00600	33035.JPJF01000076_gene5072	8.14e-86	254.0	COG1585@1|root,COG1585@2|Bacteria,1VAS9@1239|Firmicutes,24MRQ@186801|Clostridia,3Y0IA@572511|Blautia	186801|Clostridia	OU	Psort location CytoplasmicMembrane, score 9.26	-	-	-	-	-	-	-	-	-	-	-	-	NfeD
NFNHFNFO_00601	33035.JPJF01000076_gene5071	0.0	1443.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,3Y0XZ@572511|Blautia	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NFNHFNFO_00602	33035.JPJF01000076_gene5070	5.36e-148	418.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3XZQT@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_00603	33035.JPJF01000076_gene5069	9.67e-294	806.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,3XZ77@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	pbuG	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
NFNHFNFO_00604	33035.JPJF01000076_gene5068	4.77e-164	464.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,3XZXT@572511|Blautia	186801|Clostridia	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_00605	33035.JPJF01000076_gene5067	6.62e-146	413.0	COG0745@1|root,COG0745@2|Bacteria,1TSNV@1239|Firmicutes,2493A@186801|Clostridia,3Y04C@572511|Blautia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00606	33035.JPJF01000076_gene5066	1.01e-138	402.0	COG3773@1|root,COG3773@2|Bacteria,1V6F0@1239|Firmicutes,25B2E@186801|Clostridia,3Y0E4@572511|Blautia	186801|Clostridia	M	Bacterial SH3 domain	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2,SH3_3
NFNHFNFO_00607	33035.JPJF01000076_gene5065	1.32e-160	453.0	COG0566@1|root,COG0566@2|Bacteria,1V3JP@1239|Firmicutes,248DV@186801|Clostridia,3XYZF@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	spoU	-	-	ko:K03437	-	-	-	-	ko00000,ko03016	-	-	-	SpoU_methylase,SpoU_sub_bind
NFNHFNFO_00608	33035.JPJF01000076_gene5064	3.53e-150	423.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,3XZZU@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NFNHFNFO_00609	33035.JPJF01000076_gene5063	6.45e-303	830.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3XZ2Q@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NFNHFNFO_00610	33035.JPJF01000076_gene5062	2.62e-237	652.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,248PB@186801|Clostridia,3XYH6@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11	ko:K00850	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04152,ko05230,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04152,map05230	M00001,M00345	R00756,R03236,R03237,R03238,R03239,R04779	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000,ko01009,ko03019	-	-	-	PFK
NFNHFNFO_00611	33035.JPJF01000076_gene5061	0.0	2173.0	COG0587@1|root,COG0587@2|Bacteria,1TPYG@1239|Firmicutes,247U0@186801|Clostridia,3XZJ6@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 9.98	dnaE	-	2.7.7.7	ko:K02337,ko:K14162	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_alpha,HHH_6,PHP,tRNA_anti-codon
NFNHFNFO_00612	33035.JPJF01000076_gene5060	1.23e-121	349.0	COG0500@1|root,COG0500@2|Bacteria,1UI1D@1239|Firmicutes,25EAD@186801|Clostridia,3Y0F8@572511|Blautia	186801|Clostridia	Q	Tellurite resistance protein TehB	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_23,Methyltransf_25,NUDIX
NFNHFNFO_00613	33035.JPJF01000076_gene5059	5.16e-185	516.0	COG2996@1|root,COG2996@2|Bacteria,1TQ1Z@1239|Firmicutes,2498C@186801|Clostridia,3XZD5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	cvfB	-	-	ko:K00243	-	-	-	-	ko00000	-	-	-	S1,S1_2
NFNHFNFO_00614	33035.JPJF01000076_gene5058	1.81e-166	466.0	COG3884@1|root,COG3884@2|Bacteria,1TRH5@1239|Firmicutes,24G5K@186801|Clostridia,3XZPR@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	3.1.2.21	ko:K01071	ko00061,ko01100,map00061,map01100	-	R04014,R08157,R08158	RC00014,RC00039	ko00000,ko00001,ko01000,ko01004	-	-	-	Acyl-ACP_TE
NFNHFNFO_00616	33035.JPJF01000076_gene5057	3.29e-297	814.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3XYYG@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
NFNHFNFO_00617	33035.JPJF01000076_gene5056	2.21e-226	624.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,3Y1AB@572511|Blautia	186801|Clostridia	CH	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	hprA	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NFNHFNFO_00618	537007.BLAHAN_05143	8.98e-254	702.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3XZAD@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DctM
NFNHFNFO_00619	33035.JPJF01000117_gene2837	7.33e-111	320.0	COG3090@1|root,COG3090@2|Bacteria,1V6K0@1239|Firmicutes,24K3G@186801|Clostridia,3Y19Y@572511|Blautia	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
NFNHFNFO_00620	33035.JPJF01000117_gene2836	5.87e-226	625.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24C83@186801|Clostridia,3Y0JY@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
NFNHFNFO_00621	33035.JPJF01000117_gene2835	0.0	975.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3XZDA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_00622	33035.JPJF01000117_gene2834	2.49e-204	565.0	COG1830@1|root,COG1830@2|Bacteria,1TR4S@1239|Firmicutes,24CYU@186801|Clostridia,3XYSF@572511|Blautia	186801|Clostridia	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
NFNHFNFO_00623	33035.JPJF01000117_gene2833	2.1e-245	674.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,25B2J@186801|Clostridia,3XZKP@572511|Blautia	186801|Clostridia	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_00624	33035.JPJF01000117_gene2832	1.56e-178	499.0	COG1737@1|root,COG1737@2|Bacteria,1TR0N@1239|Firmicutes,25CE3@186801|Clostridia,3XZYV@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NFNHFNFO_00625	33035.JPJF01000117_gene2831	0.0	1274.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
NFNHFNFO_00626	33035.JPJF01000117_gene2830	1.15e-105	308.0	COG1876@1|root,COG1876@2|Bacteria,1V1F7@1239|Firmicutes,24E6R@186801|Clostridia,3Y0AD@572511|Blautia	186801|Clostridia	M	D-alanyl-D-alanine carboxypeptidase	-	-	3.4.17.14	ko:K07260	ko00550,ko01100,ko01502,ko02020,map00550,map01100,map01502,map02020	M00651	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko01011,ko01504	-	-	-	VanY
NFNHFNFO_00627	33035.JPJF01000117_gene2829	0.0	915.0	COG1488@1|root,COG1488@2|Bacteria,1TPDW@1239|Firmicutes,247NY@186801|Clostridia,3XZKK@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP	pncB	-	6.3.4.21	ko:K00763	ko00760,ko01100,map00760,map01100	-	R01724	RC00033	ko00000,ko00001,ko01000	-	-	-	NAPRTase,QRPTase_C,QRPTase_N
NFNHFNFO_00628	33035.JPJF01000117_gene2828	2.29e-119	342.0	COG2002@1|root,COG2002@2|Bacteria,1V02A@1239|Firmicutes,248XR@186801|Clostridia,3XZW9@572511|Blautia	186801|Clostridia	K	COG COG2002 Regulators of stationary sporulation gene expression	spoVT	-	-	ko:K04769	-	-	-	-	ko00000,ko03000	-	-	-	MazE_antitoxin,SpoVT_C
NFNHFNFO_00629	33035.JPJF01000117_gene2827	5.71e-211	584.0	COG0697@1|root,COG0697@2|Bacteria,1UYTR@1239|Firmicutes,249JF@186801|Clostridia	186801|Clostridia	EG	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_00630	33035.JPJF01000117_gene2826	1.93e-190	531.0	COG4750@1|root,COG4750@2|Bacteria,1TRCJ@1239|Firmicutes,24BS7@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	APH,Aminotran_1_2,Choline_kinase,HTH_24,NTP_transf_3
NFNHFNFO_00631	33035.JPJF01000117_gene2825	0.0	1042.0	COG0510@1|root,COG4750@1|root,COG0510@2|Bacteria,COG4750@2|Bacteria,1TRCJ@1239|Firmicutes,24BS7@186801|Clostridia,3Y18T@572511|Blautia	186801|Clostridia	M	Choline/ethanolamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	Choline_kinase,HTH_24,NTP_transf_3,NTP_transferase
NFNHFNFO_00632	33035.JPJF01000117_gene2824	3.36e-187	521.0	COG0546@1|root,COG0546@2|Bacteria,1V1RB@1239|Firmicutes,2487B@186801|Clostridia	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
NFNHFNFO_00633	33035.JPJF01000117_gene2823	1.49e-273	749.0	COG1168@1|root,COG1168@2|Bacteria,1TP5G@1239|Firmicutes,248AY@186801|Clostridia,3Y1B3@572511|Blautia	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	patB	-	4.4.1.8	ko:K14155	ko00270,ko00450,ko01100,ko01110,ko01230,map00270,map00450,map01100,map01110,map01230	-	R00782,R01286,R02408,R04941	RC00056,RC00069,RC00382,RC00488,RC00710,RC01245,RC02303	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NFNHFNFO_00634	33035.JPJF01000141_gene2452	3.21e-41	136.0	2E45D@1|root,32Z1F@2|Bacteria,1VEXR@1239|Firmicutes,24R89@186801|Clostridia,3Y0W2@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00635	272563.CD630_16510	7.26e-235	671.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
NFNHFNFO_00636	33035.JPJF01000141_gene2451	0.0	884.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia,3Y1J8@572511|Blautia	186801|Clostridia	G	Family 4 glycosyl hydrolase	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
NFNHFNFO_00637	33035.JPJF01000141_gene2450	1.89e-179	502.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,3XZEN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_00638	33035.JPJF01000141_gene2449	3.03e-181	506.0	COG4977@1|root,COG4977@2|Bacteria,1VVMD@1239|Firmicutes	1239|Firmicutes	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NFNHFNFO_00639	33035.JPJF01000141_gene2448	4.77e-231	637.0	COG1063@1|root,COG1063@2|Bacteria	2|Bacteria	E	alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
NFNHFNFO_00640	33035.JPJF01000141_gene2447	1.88e-217	603.0	COG0673@1|root,COG0673@2|Bacteria,1V0BK@1239|Firmicutes	1239|Firmicutes	S	oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C,ox_reductase_C
NFNHFNFO_00641	33035.JPJF01000141_gene2446	2.13e-194	540.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3Y2EE@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_00642	33035.JPJF01000141_gene2445	1.79e-204	566.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3XYIT@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02025,ko:K05814,ko:K17316	ko02010,map02010	M00198,M00207,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.24,3.A.1.1.3,3.A.1.1.30	-	-	BPD_transp_1
NFNHFNFO_00643	33035.JPJF01000141_gene2444	0.0	873.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24977@186801|Clostridia	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_00644	33035.JPJF01000141_gene2443	2.01e-172	483.0	COG0561@1|root,COG0561@2|Bacteria,1V1JB@1239|Firmicutes,24AY8@186801|Clostridia,3Y059@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NFNHFNFO_00645	33035.JPJF01000141_gene2440	1.23e-194	540.0	COG0726@1|root,COG0726@2|Bacteria,1TT1X@1239|Firmicutes,249PF@186801|Clostridia,3XZPS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	pdaA	-	-	ko:K01567	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
NFNHFNFO_00646	1235798.C817_02825	0.0	929.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia	186801|Clostridia	G	family 4	-	-	3.2.1.22	ko:K07406	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_4,Glyco_hydro_4C
NFNHFNFO_00647	33035.JPJF01000037_gene2999	2.49e-216	599.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UYG6@1239|Firmicutes,24JEP@186801|Clostridia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_00648	33035.JPJF01000037_gene2998	1.52e-300	820.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3XZFW@572511|Blautia	186801|Clostridia	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
NFNHFNFO_00649	33035.JPJF01000037_gene2997	1.39e-216	598.0	COG2207@1|root,COG2207@2|Bacteria,1V062@1239|Firmicutes,25B1G@186801|Clostridia,3XZV3@572511|Blautia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_00650	180332.JTGN01000009_gene4236	1.85e-114	338.0	COG3507@1|root,COG3507@2|Bacteria,1UYIB@1239|Firmicutes,24975@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_43
NFNHFNFO_00651	1410626.JHXB01000016_gene1729	9.41e-124	361.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,27IM4@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_00652	1304866.K413DRAFT_0361	2.55e-145	418.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia,36H73@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_00653	515620.EUBELI_20530	7.51e-188	537.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,25VAF@186806|Eubacteriaceae	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_00654	642492.Clole_3151	2.18e-100	301.0	COG2207@1|root,COG2207@2|Bacteria,1TR4U@1239|Firmicutes,24JVF@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	HTH_18
NFNHFNFO_00656	537007.BLAHAN_04830	3.59e-108	322.0	COG0115@1|root,COG0115@2|Bacteria,1V3JS@1239|Firmicutes,24JA5@186801|Clostridia,3Y02Q@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score	pabC	-	4.1.3.38	ko:K02619	ko00790,map00790	-	R05553	RC01843,RC02148	ko00000,ko00001,ko01000	-	-	-	Aminotran_4
NFNHFNFO_00657	537007.BLAHAN_04829	5.55e-237	662.0	COG0147@1|root,COG0147@2|Bacteria,1TQAP@1239|Firmicutes,24946@186801|Clostridia,3XZKF@572511|Blautia	186801|Clostridia	EH	Psort location Cytoplasmic, score 8.87	pabB	-	2.6.1.85,4.1.3.27,4.1.3.38	ko:K01657,ko:K01665,ko:K03342,ko:K13950	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716,R05553	RC00010,RC01418,RC01843,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Anth_synt_I_N,Chorismate_bind
NFNHFNFO_00658	537007.BLAHAN_04828	2.67e-102	302.0	COG0512@1|root,COG0512@2|Bacteria,1TT9R@1239|Firmicutes,24FR0@186801|Clostridia,3Y00Z@572511|Blautia	186801|Clostridia	EH	Psort location Cytoplasmic, score 8.87	pabA	-	2.6.1.85,4.1.3.27	ko:K01658,ko:K01664	ko00400,ko00405,ko00790,ko01100,ko01110,ko01130,ko01230,ko02024,ko02025,map00400,map00405,map00790,map01100,map01110,map01130,map01230,map02024,map02025	M00023	R00985,R00986,R01716	RC00010,RC01418,RC02148,RC02414	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17720	GATase
NFNHFNFO_00659	861454.HMPREF9099_00715	2.99e-117	349.0	COG1609@1|root,COG1609@2|Bacteria,1TRFH@1239|Firmicutes,24825@186801|Clostridia,27TA2@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_00660	592026.GCWU0000282_003047	1.61e-227	638.0	COG1653@1|root,COG1653@2|Bacteria,1TR0C@1239|Firmicutes,248RD@186801|Clostridia	186801|Clostridia	G	solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
NFNHFNFO_00661	180332.JTGN01000002_gene5509	5.31e-173	488.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_00662	180332.JTGN01000002_gene5510	4.24e-156	442.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_00663	610130.Closa_0870	0.0	944.0	COG0637@1|root,COG1554@1|root,COG0637@2|Bacteria,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,247J6@186801|Clostridia,223W0@1506553|Lachnoclostridium	186801|Clostridia	G	hydrolase family 65 central catalytic	-	-	2.4.1.230,2.4.1.8	ko:K00691,ko:K04844,ko:K10231	ko00500,ko01100,map00500,map01100	-	R01555	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
NFNHFNFO_00664	33035.JPJF01000037_gene2948	1.13e-107	315.0	COG0637@1|root,COG0637@2|Bacteria,1UZE0@1239|Firmicutes,24DWR@186801|Clostridia	186801|Clostridia	S	Haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
NFNHFNFO_00665	33035.JPJF01000037_gene2975	0.0	908.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3XZ6T@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
NFNHFNFO_00666	1536772.R70723_22925	0.0	924.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,4HB1D@91061|Bacilli,26UJI@186822|Paenibacillaceae	91061|Bacilli	G	Belongs to the glycosyl hydrolase 31 family	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,Glyco_hydro_31
NFNHFNFO_00667	394503.Ccel_2696	1.93e-86	264.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,36FX9@31979|Clostridiaceae	186801|Clostridia	K	Filamentation induced by cAMP protein fic	-	-	-	-	-	-	-	-	-	-	-	-	Fic
NFNHFNFO_00668	471875.RUMLAC_02067	1.71e-87	267.0	COG3177@1|root,COG3177@2|Bacteria,1TZWX@1239|Firmicutes,247MZ@186801|Clostridia,3WHZR@541000|Ruminococcaceae	186801|Clostridia	S	Fic/DOC family	-	-	-	-	-	-	-	-	-	-	-	-	Fic,HTH_17
NFNHFNFO_00669	411468.CLOSCI_00005	2.76e-220	613.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,247Z9@186801|Clostridia,21Y6T@1506553|Lachnoclostridium	186801|Clostridia	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
NFNHFNFO_00670	742735.HMPREF9467_04004	2.52e-170	479.0	COG2207@1|root,COG2207@2|Bacteria,1TR2K@1239|Firmicutes,24ABH@186801|Clostridia,222EH@1506553|Lachnoclostridium	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_00671	1121115.AXVN01000018_gene29	0.0	953.0	COG3119@1|root,COG3119@2|Bacteria,1TQEP@1239|Firmicutes,2482B@186801|Clostridia,3Y0RM@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
NFNHFNFO_00672	1121115.AXVN01000018_gene28	3.35e-305	835.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3XZZ6@572511|Blautia	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
NFNHFNFO_00673	33035.JPJF01000083_gene5148	2.4e-38	134.0	2CET8@1|root,2Z7N2@2|Bacteria,1TT9T@1239|Firmicutes,24AN8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00674	1235792.C808_02961	1e-114	345.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24B23@186801|Clostridia,27M2S@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
NFNHFNFO_00675	411468.CLOSCI_00876	1.94e-77	258.0	COG5492@1|root,COG5492@2|Bacteria,1VAB0@1239|Firmicutes	1239|Firmicutes	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00676	411483.FAEPRAA2165_02995	6.49e-20	85.5	2DRVZ@1|root,33DC6@2|Bacteria,1VPFD@1239|Firmicutes,24V9V@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00677	411469.EUBHAL_02834	3.83e-75	230.0	COG0681@1|root,COG0681@2|Bacteria,1V954@1239|Firmicutes,24JWF@186801|Clostridia	186801|Clostridia	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S26
NFNHFNFO_00678	1226325.HMPREF1548_03937	4.81e-88	274.0	COG2247@1|root,COG2247@2|Bacteria,1UX4H@1239|Firmicutes,257XB@186801|Clostridia,36TJG@31979|Clostridiaceae	2|Bacteria	M	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm	-	-	-	ko:K13730	ko05100,map05100	-	-	-	ko00000,ko00001	-	-	-	Big_2,Flg_new,SLH
NFNHFNFO_00679	411469.EUBHAL_02832	5.24e-128	370.0	COG4509@1|root,COG4509@2|Bacteria,1V2EF@1239|Firmicutes,24CIH@186801|Clostridia,25W42@186806|Eubacteriaceae	186801|Clostridia	S	sortase, SrtB family	-	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NFNHFNFO_00680	411469.EUBHAL_02831	1.96e-59	193.0	2ECC3@1|root,336AG@2|Bacteria,1UK74@1239|Firmicutes	1239|Firmicutes	S	Spy0128-like isopeptide containing domain	-	-	-	-	-	-	-	-	-	-	-	-	FctA
NFNHFNFO_00683	699246.HMPREF0868_0376	8.42e-165	465.0	COG1177@1|root,COG1177@2|Bacteria,1URBC@1239|Firmicutes,24801@186801|Clostridia	186801|Clostridia	P	abc transporter permease protein	-	-	-	ko:K02053	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	BPD_transp_1
NFNHFNFO_00684	1203606.HMPREF1526_01275	5.43e-168	477.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,36EAA@31979|Clostridiaceae	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	-	ko:K02052	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	ABC_tran,TOBE_2
NFNHFNFO_00685	699246.HMPREF0868_0378	1.33e-176	504.0	COG4134@1|root,COG4134@2|Bacteria,1TR3G@1239|Firmicutes,24A5K@186801|Clostridia	186801|Clostridia	S	solute-binding protein	-	-	-	ko:K02055	ko02024,map02024	M00193	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11	-	-	SBP_bac_8
NFNHFNFO_00686	699246.HMPREF0868_0379	4.75e-134	387.0	COG1176@1|root,COG1176@2|Bacteria,1TR71@1239|Firmicutes,25C51@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_00687	632245.CLP_2441	2.97e-19	85.1	COG0584@1|root,COG0584@2|Bacteria,1VE9S@1239|Firmicutes,24TKD@186801|Clostridia,36PDJ@31979|Clostridiaceae	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
NFNHFNFO_00690	1203606.HMPREF1526_00874	1.87e-25	100.0	2ENFB@1|root,33G2S@2|Bacteria,1UI8S@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00691	1203606.HMPREF1526_00873	3.89e-114	340.0	COG0613@1|root,COG0613@2|Bacteria,1V2U3@1239|Firmicutes,24CV5@186801|Clostridia,36KFA@31979|Clostridiaceae	186801|Clostridia	S	DNA polymerase alpha chain like domain	-	-	-	-	-	-	-	-	-	-	-	-	PHP
NFNHFNFO_00692	33035.JPJF01000080_gene127	1.17e-204	572.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,3XZDX@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
NFNHFNFO_00694	33035.JPJF01000080_gene125	0.0	1243.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,3Y0Y4@572511|Blautia	186801|Clostridia	U	Protein export membrane protein	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF
NFNHFNFO_00695	33035.JPJF01000080_gene124	0.0	1212.0	COG3158@1|root,COG3158@2|Bacteria,1TRUQ@1239|Firmicutes,24CIX@186801|Clostridia	186801|Clostridia	P	Transport of potassium into the cell	kup	-	-	ko:K03549	-	-	-	-	ko00000,ko02000	2.A.72	-	-	K_trans
NFNHFNFO_00696	33035.JPJF01000080_gene123	8.26e-40	132.0	COG1396@1|root,COG1396@2|Bacteria,1VEPX@1239|Firmicutes,24R13@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NFNHFNFO_00697	33035.JPJF01000080_gene122	4.7e-171	476.0	COG3822@1|root,COG3822@2|Bacteria,1UXBF@1239|Firmicutes,249XW@186801|Clostridia,3Y111@572511|Blautia	186801|Clostridia	S	Pfam:DUF1498	-	-	5.3.1.15	ko:K09988	ko00040,map00040	-	R01898	RC00516	ko00000,ko00001,ko01000	-	-	-	Lyx_isomer
NFNHFNFO_00698	33035.JPJF01000080_gene121	0.0	997.0	COG0554@1|root,COG0554@2|Bacteria,1TPX3@1239|Firmicutes,2493W@186801|Clostridia,3XZ0V@572511|Blautia	186801|Clostridia	H	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate	glpK	GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_00699	33035.JPJF01000080_gene119	5.15e-216	599.0	COG2017@1|root,COG2017@2|Bacteria,1TS8H@1239|Firmicutes,25JTW@186801|Clostridia,3Y1UN@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF4432)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4432
NFNHFNFO_00700	33035.JPJF01000082_gene5162	1.41e-191	536.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,24EHA@186801|Clostridia,3XYZC@572511|Blautia	186801|Clostridia	Q	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
NFNHFNFO_00702	33035.JPJF01000013_gene4580	4.52e-123	359.0	COG2207@1|root,COG2207@2|Bacteria,1UUUM@1239|Firmicutes,25KCJ@186801|Clostridia,3Y1WS@572511|Blautia	2|Bacteria	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_00703	33035.JPJF01000013_gene4581	1.07e-248	689.0	28MXM@1|root,2Z899@2|Bacteria,1TNYK@1239|Firmicutes,24D2N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00704	556261.HMPREF0240_01729	1.09e-114	350.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,36F95@31979|Clostridiaceae	186801|Clostridia	G	solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_00705	1232453.BAIF02000086_gene319	2.02e-136	395.0	COG1175@1|root,COG1175@2|Bacteria,1TT3G@1239|Firmicutes,24D1V@186801|Clostridia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_00706	556261.HMPREF0240_01731	1.28e-124	362.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,36FNN@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026,ko:K10242	ko02010,map02010	M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23	-	-	BPD_transp_1
NFNHFNFO_00707	180332.JTGN01000023_gene1656	9.54e-66	229.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1VR4Z@1239|Firmicutes,24C19@186801|Clostridia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_00708	556261.HMPREF0240_01734	3.38e-126	390.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,248RT@186801|Clostridia,36G92@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NFNHFNFO_00709	33035.JPJF01000082_gene5164	7.39e-189	525.0	COG0648@1|root,COG0648@2|Bacteria,1TP1D@1239|Firmicutes,2499E@186801|Clostridia,3XZMX@572511|Blautia	186801|Clostridia	L	Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin	nfo	-	3.1.21.2	ko:K01151	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AP_endonuc_2
NFNHFNFO_00710	33035.JPJF01000082_gene5165	4.9e-239	657.0	COG0232@1|root,COG0232@2|Bacteria,1TPEI@1239|Firmicutes,247Q1@186801|Clostridia,3XYN7@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	dgt	-	3.1.5.1	ko:K01129	ko00230,map00230	-	R01856	RC00017	ko00000,ko00001,ko01000	-	-	-	HD,HD_assoc
NFNHFNFO_00711	33035.JPJF01000082_gene5166	0.0	1098.0	COG0358@1|root,COG0358@2|Bacteria,1TQ0X@1239|Firmicutes,2480W@186801|Clostridia,3XYMV@572511|Blautia	186801|Clostridia	L	RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication	dnaG	-	-	ko:K02316	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_bind,Toprim_2,Toprim_4,Toprim_N,zf-CHC2
NFNHFNFO_00712	33035.JPJF01000082_gene5167	1.37e-252	695.0	COG0568@1|root,COG0568@2|Bacteria,1TPD6@1239|Firmicutes,2481I@186801|Clostridia,3XZ4I@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth	sigA	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r1_1,Sigma70_r1_2,Sigma70_r2,Sigma70_r3,Sigma70_r4
NFNHFNFO_00713	33035.JPJF01000082_gene5168	5.62e-137	391.0	COG2384@1|root,COG2384@2|Bacteria,1V3I4@1239|Firmicutes,24BJI@186801|Clostridia,3XZUP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	trmK	-	2.1.1.217	ko:K06967	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_18,TrmK
NFNHFNFO_00714	33035.JPJF01000082_gene5169	3.58e-167	469.0	COG0327@1|root,COG0327@2|Bacteria,1TQ27@1239|Firmicutes,248Q2@186801|Clostridia,3XYVV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NIF3
NFNHFNFO_00715	33035.JPJF01000082_gene5170	0.0	1087.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,249IT@186801|Clostridia,3XYSM@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
NFNHFNFO_00716	33035.JPJF01000077_gene25	1.41e-303	828.0	COG2607@1|root,COG2607@2|Bacteria,1TQDJ@1239|Firmicutes,2483S@186801|Clostridia,3XZFR@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06923	-	-	-	-	ko00000	-	-	-	DUF815
NFNHFNFO_00717	33035.JPJF01000077_gene26	2.64e-244	674.0	COG0077@1|root,COG1605@1|root,COG0077@2|Bacteria,COG1605@2|Bacteria,1TPDN@1239|Firmicutes,248G7@186801|Clostridia,3XYHH@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	pheA	-	4.2.1.51,5.4.99.5	ko:K04518,ko:K14170	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R00691,R01373,R01715	RC00360,RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,CM_2,PDT
NFNHFNFO_00718	1256908.HMPREF0373_00976	3.37e-148	421.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,25V99@186806|Eubacteriaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_00719	1256908.HMPREF0373_00977	0.0	907.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,25V5H@186806|Eubacteriaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NFNHFNFO_00720	1256908.HMPREF0373_00978	8.35e-118	342.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,25V3T@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00721	1256908.HMPREF0373_00979	2.23e-154	443.0	COG5002@1|root,COG5002@2|Bacteria,1UI6U@1239|Firmicutes,25H6P@186801|Clostridia	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
NFNHFNFO_00722	33035.JPJF01000077_gene27	2.39e-94	274.0	COG4905@1|root,COG4905@2|Bacteria,1VAQJ@1239|Firmicutes,24K5I@186801|Clostridia,3Y0E6@572511|Blautia	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NFNHFNFO_00723	33035.JPJF01000077_gene28	1.08e-211	585.0	COG0540@1|root,COG0540@2|Bacteria,1TQ96@1239|Firmicutes,2496D@186801|Clostridia,3XZCV@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 9.98	pyrB	-	2.1.3.2	ko:K00609	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002,ko01000	-	-	-	OTCace,OTCace_N,PyrI_C
NFNHFNFO_00724	33035.JPJF01000077_gene29	1.09e-100	291.0	COG1781@1|root,COG1781@2|Bacteria,1V6U9@1239|Firmicutes,24JJU@186801|Clostridia,3XZVS@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	pyrI	-	-	ko:K00610	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R01397	RC00064,RC02850	ko00000,ko00001,ko00002	-	-	-	PyrI,PyrI_C
NFNHFNFO_00725	33035.JPJF01000077_gene30	1.65e-213	590.0	COG1893@1|root,COG1893@2|Bacteria,1UM1M@1239|Firmicutes,249J4@186801|Clostridia,3Y2A5@572511|Blautia	186801|Clostridia	H	Ketopantoate reductase PanE/ApbA C terminal	-	-	1.1.1.169	ko:K00077	ko00770,ko01100,ko01110,map00770,map01100,map01110	M00119	R02472	RC00726	ko00000,ko00001,ko00002,ko01000	-	-	-	ApbA,ApbA_C
NFNHFNFO_00726	33035.JPJF01000077_gene33	2.94e-300	822.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3XYPM@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_00727	33035.JPJF01000077_gene34	7.6e-96	283.0	COG1309@1|root,COG1309@2|Bacteria,1V7CM@1239|Firmicutes,24K3K@186801|Clostridia,3Y0PF@572511|Blautia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_00728	33035.JPJF01000077_gene35	2.02e-81	243.0	2C5N5@1|root,32Y15@2|Bacteria,1VEIC@1239|Firmicutes,24I2X@186801|Clostridia,3Y0C0@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00729	33035.JPJF01000077_gene36	6.11e-301	826.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZ7Q@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_00730	33035.JPJF01000077_gene37	2.24e-157	445.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,249RU@186801|Clostridia,3Y193@572511|Blautia	186801|Clostridia	EG	Triose-phosphate Transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_00731	33035.JPJF01000077_gene38	1.07e-242	667.0	COG0303@1|root,COG0303@2|Bacteria,1TP7F@1239|Firmicutes,247TZ@186801|Clostridia,3XZT8@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	moeA2	-	-	-	-	-	-	-	-	-	-	-	MoCF_biosynth
NFNHFNFO_00732	33035.JPJF01000077_gene39	2.28e-201	560.0	COG1975@1|root,COG1975@2|Bacteria,1UZDB@1239|Firmicutes,25D6N@186801|Clostridia,3XZKY@572511|Blautia	186801|Clostridia	O	COG COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	XdhC_C,XdhC_CoxI
NFNHFNFO_00733	33035.JPJF01000077_gene41	1.79e-146	420.0	COG0725@1|root,COG0725@2|Bacteria,1U9U3@1239|Firmicutes,249VA@186801|Clostridia,3Y07V@572511|Blautia	186801|Clostridia	P	COG COG0725 ABC-type molybdate transport system, periplasmic component	modA	-	-	ko:K02020	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	iHN637.CLJU_RS12820	SBP_bac_11
NFNHFNFO_00734	33035.JPJF01000077_gene42	1.36e-146	414.0	COG4149@1|root,COG4149@2|Bacteria,1TRNA@1239|Firmicutes,24BR9@186801|Clostridia,3XZF3@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	modB	-	-	ko:K02018	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.8	-	-	BPD_transp_1
NFNHFNFO_00735	33035.JPJF01000077_gene43	1.95e-231	639.0	COG1118@1|root,COG1118@2|Bacteria,1UI1E@1239|Firmicutes,25EAE@186801|Clostridia	186801|Clostridia	P	ABC transporter	modC	-	3.6.3.29	ko:K02017	ko02010,map02010	M00189	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.8	-	-	ABC_tran
NFNHFNFO_00736	33035.JPJF01000077_gene44	1.94e-110	318.0	COG1522@1|root,COG1522@2|Bacteria,1V3PB@1239|Firmicutes,24I3N@186801|Clostridia,3Y05J@572511|Blautia	186801|Clostridia	K	Lrp/AsnC ligand binding domain	yugG	-	-	-	-	-	-	-	-	-	-	-	AsnC_trans_reg,HTH_24
NFNHFNFO_00737	33035.JPJF01000077_gene45	2.17e-267	733.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3XYJ7@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	aspC	-	-	ko:K10907	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	Aminotran_1_2
NFNHFNFO_00738	33035.JPJF01000077_gene46	2.82e-314	856.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3XYV0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	thrA	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
NFNHFNFO_00739	33035.JPJF01000077_gene47	7.41e-191	533.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,3XYVT@572511|Blautia	186801|Clostridia	C	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	hprA	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NFNHFNFO_00741	33035.JPJF01000077_gene49	4.03e-83	246.0	COG0824@1|root,COG0824@2|Bacteria,1VAGM@1239|Firmicutes,24NBX@186801|Clostridia,3Y0GI@572511|Blautia	186801|Clostridia	S	Thioesterase-like superfamily	FcbC	-	-	ko:K07107	-	-	-	-	ko00000,ko01000	-	-	-	4HBT,4HBT_2
NFNHFNFO_00742	33035.JPJF01000077_gene50	4.37e-81	240.0	COG1725@1|root,COG1725@2|Bacteria,1VFD0@1239|Firmicutes,24MTU@186801|Clostridia,3Y09K@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NFNHFNFO_00743	33035.JPJF01000077_gene51	2.84e-209	579.0	COG1131@1|root,COG1131@2|Bacteria,1TPQW@1239|Firmicutes,248F7@186801|Clostridia,3XYHB@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	ytrB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_00744	33035.JPJF01000077_gene52	0.0	1084.0	COG1277@1|root,COG1277@2|Bacteria,1TRJ8@1239|Firmicutes,24EMN@186801|Clostridia,3Y097@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	-
NFNHFNFO_00745	33035.JPJF01000077_gene53	7.03e-216	596.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia,3Y1F8@572511|Blautia	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
NFNHFNFO_00746	33035.JPJF01000077_gene54	1.53e-267	734.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3XZEU@572511|Blautia	186801|Clostridia	H	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
NFNHFNFO_00747	33035.JPJF01000077_gene55	0.0	983.0	COG4468@1|root,COG4468@2|Bacteria,1TPBN@1239|Firmicutes,247ZN@186801|Clostridia,3XZID@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	galT	-	2.7.7.12	ko:K00965	ko00052,ko00520,ko01100,ko04917,map00052,map00520,map01100,map04917	M00362,M00554,M00632	R00955	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	GalP_UDP_tr_C,GalP_UDP_transf
NFNHFNFO_00748	33035.JPJF01000077_gene56	1e-100	292.0	COG1607@1|root,COG1607@2|Bacteria,1V3S2@1239|Firmicutes,24JIT@186801|Clostridia,3Y071@572511|Blautia	186801|Clostridia	I	Thioesterase superfamily	yciA	-	-	-	-	-	-	-	-	-	-	-	4HBT
NFNHFNFO_00749	33035.JPJF01000077_gene57	0.0	1666.0	COG0258@1|root,COG0749@1|root,COG0258@2|Bacteria,COG0749@2|Bacteria,1TPKJ@1239|Firmicutes,248NG@186801|Clostridia,3XYYX@572511|Blautia	186801|Clostridia	L	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity	polA	-	2.7.7.7	ko:K02335	ko00230,ko00240,ko01100,ko03030,ko03410,ko03420,ko03440,map00230,map00240,map01100,map03030,map03410,map03420,map03440	-	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	5_3_exonuc,5_3_exonuc_N,DNA_pol_A,DNA_pol_A_exo1
NFNHFNFO_00750	33035.JPJF01000077_gene58	9.67e-137	387.0	COG0237@1|root,COG0237@2|Bacteria,1V6FS@1239|Firmicutes,24GFQ@186801|Clostridia,3Y05Z@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A	coaE	-	2.7.1.24	ko:K00859	ko00770,ko01100,map00770,map01100	M00120	R00130	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CoaE
NFNHFNFO_00751	33035.JPJF01000077_gene59	2.06e-189	526.0	COG1235@1|root,COG1235@2|Bacteria,1TQ8E@1239|Firmicutes,249U2@186801|Clostridia,3XYGN@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yycJ	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B,Lactamase_B_2
NFNHFNFO_00752	33035.JPJF01000077_gene60	1.01e-52	166.0	COG3830@1|root,COG3830@2|Bacteria,1VENW@1239|Firmicutes,24QNV@186801|Clostridia,3Y0FS@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07166	-	-	-	-	ko00000	-	-	-	ACT_6
NFNHFNFO_00753	33035.JPJF01000077_gene61	0.0	870.0	COG2848@1|root,COG2848@2|Bacteria,1TQG8@1239|Firmicutes,247K4@186801|Clostridia,3XYI2@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K09157	-	-	-	-	ko00000	-	-	-	DUF711
NFNHFNFO_00754	33035.JPJF01000077_gene62	1.71e-34	118.0	COG1918@1|root,COG1918@2|Bacteria,1VEYA@1239|Firmicutes,24QKX@186801|Clostridia,3Y0RP@572511|Blautia	186801|Clostridia	P	COG COG1918 Fe2 transport system protein A	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NFNHFNFO_00755	33035.JPJF01000077_gene63	2.13e-44	144.0	COG1918@1|root,COG1918@2|Bacteria,1VEHC@1239|Firmicutes,24QKE@186801|Clostridia,3Y0MM@572511|Blautia	186801|Clostridia	P	COG COG1918 Fe2 transport system protein A	feoA	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NFNHFNFO_00756	33035.JPJF01000077_gene64	0.0	1351.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3XZAE@572511|Blautia	186801|Clostridia	P	Ferrous iron transport protein B	feoB	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
NFNHFNFO_00757	33035.JPJF01000077_gene66	1.86e-203	574.0	COG1323@1|root,COG1323@2|Bacteria,1TPP2@1239|Firmicutes,247UP@186801|Clostridia,3XYI6@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HIGH_NTase1
NFNHFNFO_00758	33035.JPJF01000077_gene67	1.33e-285	781.0	COG0282@1|root,COG0282@2|Bacteria,1TQ22@1239|Firmicutes,248ZM@186801|Clostridia,3XZFQ@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction	ackA	-	2.7.2.1	ko:K00925	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00315,R01353	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetate_kinase
NFNHFNFO_00759	33035.JPJF01000077_gene68	6.39e-119	340.0	COG1399@1|root,COG1399@2|Bacteria,1VEXU@1239|Firmicutes,24RKT@186801|Clostridia,3Y029@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07040	-	-	-	-	ko00000	-	-	-	DUF177
NFNHFNFO_00760	476272.RUMHYD_00262	3.26e-36	122.0	COG0333@1|root,COG0333@2|Bacteria,1VEFI@1239|Firmicutes,24QM0@186801|Clostridia,3Y0IR@572511|Blautia	186801|Clostridia	J	Belongs to the bacterial ribosomal protein bL32 family	rpmF	-	-	ko:K02911	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_L32p
NFNHFNFO_00761	33035.JPJF01000077_gene69	1.56e-134	387.0	COG3291@1|root,COG5263@1|root,COG3291@2|Bacteria,COG5263@2|Bacteria,1VGIF@1239|Firmicutes,24REI@186801|Clostridia,3Y1NH@572511|Blautia	186801|Clostridia	S	repeat protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00762	33035.JPJF01000077_gene70	3.19e-223	617.0	COG0416@1|root,COG0416@2|Bacteria,1TPXS@1239|Firmicutes,247KW@186801|Clostridia,3XYGR@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA	plsX	-	2.3.1.15	ko:K03621	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FA_synthesis
NFNHFNFO_00763	33035.JPJF01000077_gene71	2.97e-41	136.0	COG0236@1|root,COG0236@2|Bacteria,1UGNP@1239|Firmicutes,25P5Y@186801|Clostridia,3Y0KT@572511|Blautia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NFNHFNFO_00764	33035.JPJF01000077_gene72	9.13e-161	451.0	COG0571@1|root,COG0571@2|Bacteria,1TPGC@1239|Firmicutes,249QD@186801|Clostridia,3XZ9W@572511|Blautia	186801|Clostridia	J	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism	rnc	-	3.1.26.3	ko:K03685	ko03008,ko05205,map03008,map05205	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019,ko03036	-	-	-	Ribonucleas_3_3,dsrm
NFNHFNFO_00765	33035.JPJF01000077_gene73	0.0	1684.0	COG1196@1|root,COG1196@2|Bacteria,1TPJV@1239|Firmicutes,249F4@186801|Clostridia,3XYK7@572511|Blautia	186801|Clostridia	D	Required for chromosome condensation and partitioning	smc	-	-	ko:K03529	-	-	-	-	ko00000,ko03036	-	-	-	SMC_N,SMC_hinge
NFNHFNFO_00766	33035.JPJF01000077_gene74	8.75e-210	581.0	COG0552@1|root,COG0552@2|Bacteria,1TPRI@1239|Firmicutes,247JD@186801|Clostridia,3XZT9@572511|Blautia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)	ftsY	-	-	ko:K03110	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2,3.A.5.7	-	-	SRP54,SRP54_N
NFNHFNFO_00767	33035.JPJF01000077_gene75	5.06e-280	766.0	COG1171@1|root,COG1171@2|Bacteria,1TP22@1239|Firmicutes,248D5@186801|Clostridia,3XYJM@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ilvA	-	4.3.1.19	ko:K01754	ko00260,ko00290,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00290,map01100,map01110,map01130,map01200,map01230	M00570	R00220,R00996	RC00418,RC02600	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PALP
NFNHFNFO_00768	33035.JPJF01000077_gene76	1.12e-98	292.0	2EF1U@1|root,338UW@2|Bacteria,1VFI3@1239|Firmicutes,24G8I@186801|Clostridia,3Y0T5@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00769	33035.JPJF01000060_gene2355	1.8e-250	689.0	COG2768@1|root,COG2768@2|Bacteria,1TQAW@1239|Firmicutes,247IS@186801|Clostridia,3XYVJ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07138	-	-	-	-	ko00000	-	-	-	DUF362,Fer4,Fer4_21,Fer4_6,Fer4_7
NFNHFNFO_00770	33035.JPJF01000060_gene2356	4.43e-238	665.0	COG1641@1|root,COG1641@2|Bacteria,1TPAV@1239|Firmicutes,247ZH@186801|Clostridia,3XZGY@572511|Blautia	186801|Clostridia	S	Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes	larC	-	4.99.1.12	ko:K09121	-	-	-	-	ko00000,ko01000	-	-	-	DUF111
NFNHFNFO_00771	33035.JPJF01000060_gene2357	6.58e-166	467.0	COG1606@1|root,COG1606@2|Bacteria,1TPB2@1239|Firmicutes,2485J@186801|Clostridia,3Y0BE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06864	-	-	-	-	ko00000	-	-	-	ATP_bind_3,Asn_synthase,NAD_synthase,QueC
NFNHFNFO_00773	33035.JPJF01000060_gene2358	1.16e-132	378.0	COG1309@1|root,COG1309@2|Bacteria,1VBYY@1239|Firmicutes,24NAP@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	ko:K22106	-	-	-	-	ko00000,ko03000	-	-	-	TetR_N
NFNHFNFO_00774	33035.JPJF01000060_gene2359	2.77e-296	812.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3XZU5@572511|Blautia	186801|Clostridia	G	COG COG2211 Na melibiose symporter and related transporters	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_00776	397291.C804_04065	2.31e-36	133.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,27IHK@186928|unclassified Lachnospiraceae	186801|Clostridia	LU	DNA recombination-mediator protein A	-	-	-	-	-	-	-	-	-	-	-	-	DNA_processg_A
NFNHFNFO_00777	33035.JPJF01000060_gene2361	7e-71	214.0	COG2739@1|root,COG2739@2|Bacteria,1VEGP@1239|Firmicutes,24QNM@186801|Clostridia,3Y0C3@572511|Blautia	186801|Clostridia	S	Might take part in the signal recognition particle (SRP) pathway. This is inferred from the conservation of its genetic proximity to ftsY ffh. May be a regulatory protein	-	-	-	ko:K09787	-	-	-	-	ko00000	-	-	-	UPF0122
NFNHFNFO_00778	33035.JPJF01000060_gene2362	7.28e-289	793.0	COG0541@1|root,COG0541@2|Bacteria,1TP06@1239|Firmicutes,248EU@186801|Clostridia,3XZA0@572511|Blautia	186801|Clostridia	U	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY	ffh	-	3.6.5.4	ko:K03106	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko01000,ko02044	3.A.5.1,3.A.5.2,3.A.5.7,3.A.5.8,3.A.5.9	-	-	SRP54,SRP54_N,SRP_SPB
NFNHFNFO_00779	658655.HMPREF0988_01704	1.16e-47	152.0	COG0228@1|root,COG0228@2|Bacteria,1VA0X@1239|Firmicutes,24MND@186801|Clostridia,27NX3@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein S16	rpsP	-	-	ko:K02959	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S16
NFNHFNFO_00780	33035.JPJF01000060_gene2364	5.99e-41	135.0	COG1837@1|root,COG1837@2|Bacteria,1VEG7@1239|Firmicutes,24QKN@186801|Clostridia,3Y0D4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ylqC	-	-	ko:K06960	-	-	-	-	ko00000	-	-	-	KH_4
NFNHFNFO_00781	33035.JPJF01000060_gene2365	3.45e-111	320.0	COG0806@1|root,COG0806@2|Bacteria,1V6HD@1239|Firmicutes,24I1G@186801|Clostridia,3Y02M@572511|Blautia	186801|Clostridia	J	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes	rimM	-	-	ko:K02860	-	-	-	-	ko00000,ko03009	-	-	-	PRC,RimM
NFNHFNFO_00782	33035.JPJF01000060_gene2366	4.44e-314	860.0	COG0336@1|root,COG0336@2|Bacteria,1TPBV@1239|Firmicutes,247JF@186801|Clostridia,3XYT2@572511|Blautia	186801|Clostridia	J	Belongs to the RNA methyltransferase TrmD family	trmD	-	2.1.1.228	ko:K00554	-	-	R00597	RC00003,RC00334	ko00000,ko01000,ko03016	-	-	-	tRNA_m1G_MT
NFNHFNFO_00783	33035.JPJF01000060_gene2368	4.16e-58	181.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NFNHFNFO_00784	33035.JPJF01000060_gene2369	2.56e-292	802.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,24870@186801|Clostridia,3XYYC@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf,CoA_binding_3
NFNHFNFO_00786	411463.EUBVEN_01489	9.77e-213	594.0	COG0438@1|root,COG0438@2|Bacteria,1TR0Y@1239|Firmicutes,24B5E@186801|Clostridia,25ZDW@186806|Eubacteriaceae	186801|Clostridia	M	Domain of unknown function (DUF1972)	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
NFNHFNFO_00787	411463.EUBVEN_01488	1.3e-249	689.0	COG0438@1|root,COG0438@2|Bacteria,1V0JW@1239|Firmicutes,24CKB@186801|Clostridia,25XU5@186806|Eubacteriaceae	186801|Clostridia	M	Glycosyltransferase Family 4	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
NFNHFNFO_00788	742742.HMPREF9452_00651	4.72e-84	265.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	oatA	-	-	ko:K16568	-	-	-	-	ko00000	-	-	-	Acyl_transf_3
NFNHFNFO_00789	742740.HMPREF9474_01720	1.52e-269	749.0	COG0438@1|root,COG0535@1|root,COG0438@2|Bacteria,COG0535@2|Bacteria,1UXWS@1239|Firmicutes,247NG@186801|Clostridia,21Y9U@1506553|Lachnoclostridium	186801|Clostridia	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K22227	-	-	-	-	ko00000	-	-	-	Fer4_12,Fer4_14,Radical_SAM,SPASM
NFNHFNFO_00790	478749.BRYFOR_06591	9.24e-131	380.0	COG0463@1|root,COG0463@2|Bacteria,1V8T1@1239|Firmicutes,24E8C@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NFNHFNFO_00792	742742.HMPREF9452_00650	7.69e-50	170.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	lpg2	-	2.4.1.337	ko:K00754,ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
NFNHFNFO_00793	742742.HMPREF9452_00650	3.85e-36	133.0	COG0438@1|root,COG0438@2|Bacteria	2|Bacteria	M	transferase activity, transferring glycosyl groups	lpg2	-	2.4.1.337	ko:K00754,ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
NFNHFNFO_00794	742742.HMPREF9452_00649	1.99e-187	526.0	28PSK@1|root,2ZCE3@2|Bacteria,2IBFI@201174|Actinobacteria	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00795	742742.HMPREF9452_00648	2.14e-102	300.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	capG	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2
NFNHFNFO_00796	742742.HMPREF9452_00647	2.96e-103	314.0	COG4763@1|root,COG4763@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NFNHFNFO_00797	742742.HMPREF9452_00646	1.07e-103	312.0	COG3774@1|root,COG3774@2|Bacteria,2ICTC@201174|Actinobacteria	201174|Actinobacteria	M	Capsular polysaccharide synthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Caps_synth
NFNHFNFO_00799	742742.HMPREF9452_00645	1e-123	372.0	2E63C@1|root,330SF@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00800	742742.HMPREF9452_00644	1.1e-145	431.0	COG2244@1|root,COG2244@2|Bacteria,2I9QU@201174|Actinobacteria	201174|Actinobacteria	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
NFNHFNFO_00801	742742.HMPREF9452_00643	2.78e-11	66.2	COG3274@1|root,COG3274@2|Bacteria,2IPK1@201174|Actinobacteria,4CYAY@84998|Coriobacteriia	84998|Coriobacteriia	S	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NFNHFNFO_00802	926550.CLDAP_36550	1.16e-09	59.7	COG0601@1|root,COG0601@2|Bacteria	2|Bacteria	P	nitrogen compound transport	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NFNHFNFO_00803	1122132.AQYH01000004_gene1671	4.19e-226	649.0	COG0747@1|root,COG0747@2|Bacteria,1R49R@1224|Proteobacteria,2U1IU@28211|Alphaproteobacteria,4BBXQ@82115|Rhizobiaceae	28211|Alphaproteobacteria	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NFNHFNFO_00804	1234664.AMRO01000003_gene621	3.58e-31	134.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSKR@1239|Firmicutes,4H9R5@91061|Bacilli,1WFFX@129337|Geobacillus	91061|Bacilli	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NFNHFNFO_00805	33035.JPJF01000004_gene1965	3.82e-310	848.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NFNHFNFO_00806	33035.JPJF01000004_gene1964	0.0	2094.0	COG1074@1|root,COG1074@2|Bacteria,1TQ35@1239|Firmicutes,248ZF@186801|Clostridia,3XYPU@572511|Blautia	186801|Clostridia	L	ATP-dependent helicase nuclease subunit A	addA	-	3.6.4.12	ko:K16898	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	PDDEXK_1,UvrD-helicase,UvrD_C
NFNHFNFO_00807	33035.JPJF01000004_gene1963	0.0	2061.0	COG3857@1|root,COG3857@2|Bacteria,1TQJW@1239|Firmicutes,2487T@186801|Clostridia,3XYMT@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	addB	-	3.6.4.12	ko:K16899	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	Exonuc_V_gamma,PDDEXK_1,UvrD_C
NFNHFNFO_00808	33035.JPJF01000004_gene1962	1.6e-182	509.0	COG0561@1|root,COG0561@2|Bacteria,1TR16@1239|Firmicutes,248MW@186801|Clostridia,3XZU4@572511|Blautia	186801|Clostridia	S	Sucrose-6F-phosphate phosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NFNHFNFO_00809	33035.JPJF01000004_gene1961	1.78e-81	243.0	COG3976@1|root,COG3976@2|Bacteria,1V72R@1239|Firmicutes,24JFD@186801|Clostridia,3Y05F@572511|Blautia	186801|Clostridia	S	FMN-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00810	33035.JPJF01000004_gene1960	1.96e-239	663.0	COG1388@1|root,COG3757@1|root,COG1388@2|Bacteria,COG3757@2|Bacteria,1V484@1239|Firmicutes,24A8T@186801|Clostridia,3Y2DQ@572511|Blautia	186801|Clostridia	M	Lysin motif	lyc2	GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	3.2.1.17	ko:K01185,ko:K07273	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,Glyco_hydro_25,LysM,PG_binding_1,SH3_3
NFNHFNFO_00811	1122918.KB907282_gene4967	2.6e-103	310.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,4HASN@91061|Bacilli,26SH6@186822|Paenibacillaceae	91061|Bacilli	G	COG0395 ABC-type sugar transport system, permease component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_00812	858215.Thexy_1726	3.98e-108	322.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,42FIE@68295|Thermoanaerobacterales	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_00813	1122918.KB907282_gene4969	5.26e-88	281.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,4HB0G@91061|Bacilli,26UZ8@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_00814	1195236.CTER_1950	1.11e-75	255.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3WIY2@541000|Ruminococcaceae	186801|Clostridia	K	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NFNHFNFO_00815	398512.JQKC01000017_gene3034	3.38e-77	263.0	COG2972@1|root,COG2972@2|Bacteria,1TT1G@1239|Firmicutes,2495G@186801|Clostridia,3WIVH@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,dCache_1
NFNHFNFO_00816	1105031.HMPREF1141_3560	7.81e-76	237.0	COG2159@1|root,COG2159@2|Bacteria,1V72X@1239|Firmicutes,24FW1@186801|Clostridia,36Q1E@31979|Clostridiaceae	186801|Clostridia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
NFNHFNFO_00817	457421.CBFG_03788	9.37e-285	791.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,2684H@186813|unclassified Clostridiales	186801|Clostridia	EG	Dehydratase family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
NFNHFNFO_00818	324057.Pjdr2_0297	1.96e-254	741.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,4HDFB@91061|Bacilli,26VW6@186822|Paenibacillaceae	91061|Bacilli	G	Bacterial alpha-L-rhamnosidase C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
NFNHFNFO_00819	1120950.KB892794_gene2330	9.85e-35	136.0	COG1063@1|root,COG1063@2|Bacteria,2GKU2@201174|Actinobacteria,4DSG4@85009|Propionibacteriales	201174|Actinobacteria	E	Dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
NFNHFNFO_00820	742740.HMPREF9474_00636	3.14e-139	405.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24XW6@186801|Clostridia,21ZD2@1506553|Lachnoclostridium	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_00821	33035.JPJF01000004_gene1959	3.14e-194	540.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A48@186801|Clostridia,3Y0BN@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_00822	33035.JPJF01000004_gene1958	2.49e-223	618.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia,3XZ1D@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_00823	33035.JPJF01000004_gene1957	1.59e-315	860.0	COG1653@1|root,COG1653@2|Bacteria,1TQHT@1239|Firmicutes,249J6@186801|Clostridia,3XZHY@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
NFNHFNFO_00824	33035.JPJF01000004_gene1956	1.2e-221	614.0	COG1609@1|root,COG1609@2|Bacteria,1TS5M@1239|Firmicutes,24AWP@186801|Clostridia,3Y018@572511|Blautia	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_00825	33035.JPJF01000004_gene1955	0.0	1308.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3XYP0@572511|Blautia	186801|Clostridia	G	Galactose mutarotase-like	-	-	3.2.1.20	ko:K01187	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00028,R00801,R00802,R06087,R06088	RC00028,RC00049,RC00077	ko00000,ko00001,ko01000	-	GH31	-	DUF5110,Gal_mutarotas_2,Glyco_hydro_31
NFNHFNFO_00827	33035.JPJF01000004_gene1953	1.34e-211	587.0	COG0673@1|root,COG0673@2|Bacteria,1TPT5@1239|Firmicutes,248MV@186801|Clostridia,3Y29U@572511|Blautia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NFNHFNFO_00828	33035.JPJF01000004_gene1952	1.52e-242	669.0	COG1063@1|root,COG1063@2|Bacteria,1TPIW@1239|Firmicutes,24AY7@186801|Clostridia,3XYJG@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	ko:K18369	ko00640,map00640	-	R10703	RC00545	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_N_assoc,ADH_zinc_N,ADH_zinc_N_2
NFNHFNFO_00829	33035.JPJF01000004_gene1951	0.0	1241.0	COG0171@1|root,COG0388@1|root,COG0171@2|Bacteria,COG0388@2|Bacteria,1TQ38@1239|Firmicutes,2484Z@186801|Clostridia,3XZ2F@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source	nadE	-	6.3.5.1	ko:K01950	ko00760,ko01100,map00760,map01100	M00115	R00257	RC00010,RC00100	ko00000,ko00001,ko00002,ko01000	-	-	-	CN_hydrolase,NAD_synthase
NFNHFNFO_00830	33035.JPJF01000004_gene1950	1.02e-199	554.0	COG1281@1|root,COG1281@2|Bacteria,1TRCH@1239|Firmicutes,24940@186801|Clostridia,3XYXT@572511|Blautia	186801|Clostridia	O	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress	hslO	-	-	ko:K04083	-	-	-	-	ko00000,ko03110	-	-	-	HSP33
NFNHFNFO_00831	33035.JPJF01000004_gene1949	1.26e-168	472.0	COG4976@1|root,COG4976@2|Bacteria,1UHZM@1239|Firmicutes,24A6U@186801|Clostridia,3XYHA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
NFNHFNFO_00832	411459.RUMOBE_02166	6.49e-77	238.0	COG0657@1|root,COG0657@2|Bacteria	2|Bacteria	I	acetylesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,F5_F8_type_C,Peptidase_S9
NFNHFNFO_00833	33035.JPJF01000004_gene1948	0.0	1333.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3XZXF@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NFNHFNFO_00834	33035.JPJF01000004_gene1947	0.0	925.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UCUQ@1239|Firmicutes,24FD5@186801|Clostridia,3Y1DI@572511|Blautia	186801|Clostridia	KT	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_00835	33035.JPJF01000004_gene1946	0.0	1051.0	COG2972@1|root,COG2972@2|Bacteria,1U6WN@1239|Firmicutes,257VB@186801|Clostridia,3Y13A@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NFNHFNFO_00836	33035.JPJF01000004_gene1945	6.14e-204	565.0	COG0395@1|root,COG0395@2|Bacteria,1TP1G@1239|Firmicutes,247T2@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_00837	33035.JPJF01000004_gene1944	3.5e-200	556.0	COG4209@1|root,COG4209@2|Bacteria,1TQFY@1239|Firmicutes,24923@186801|Clostridia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NFNHFNFO_00838	33035.JPJF01000004_gene1943	0.0	951.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,25NJ2@186801|Clostridia,3Y1EP@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3502
NFNHFNFO_00839	33035.JPJF01000032_gene2144	1.34e-31	110.0	2EG1V@1|root,339TV@2|Bacteria,1VKAZ@1239|Firmicutes,24UGV@186801|Clostridia,3Y0SX@572511|Blautia	186801|Clostridia	S	COG NOG17973 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF4250
NFNHFNFO_00840	33035.JPJF01000032_gene2145	0.0	1626.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3XZ90@572511|Blautia	186801|Clostridia	O	Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE	clpB	-	-	ko:K03695,ko:K03696	ko01100,ko04213,map01100,map04213	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
NFNHFNFO_00841	1121115.AXVN01000015_gene3714	3.66e-118	340.0	28KUY@1|root,2ZABM@2|Bacteria,1TRCY@1239|Firmicutes,24DJQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00842	1121115.AXVN01000015_gene3713	8.6e-249	691.0	COG4637@1|root,COG4637@2|Bacteria,1V0AZ@1239|Firmicutes,24BES@186801|Clostridia	186801|Clostridia	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
NFNHFNFO_00844	1226325.HMPREF1548_06389	3.97e-30	131.0	2CF9F@1|root,32VJR@2|Bacteria,1UKPA@1239|Firmicutes	1239|Firmicutes	S	CRISPR-associated (Cas) DxTHG family	-	-	-	-	-	-	-	-	-	-	-	-	Cas_DxTHG
NFNHFNFO_00845	397291.C804_01799	6.12e-169	506.0	COG1337@1|root,COG1337@2|Bacteria,1UZIC@1239|Firmicutes,24K3J@186801|Clostridia,27NE8@186928|unclassified Lachnospiraceae	186801|Clostridia	L	RAMP superfamily	-	-	-	-	-	-	-	-	-	-	-	-	RAMPs
NFNHFNFO_00847	397291.C804_01797	3.65e-105	327.0	COG1337@1|root,COG1337@2|Bacteria,1V6T4@1239|Firmicutes,24J7Z@186801|Clostridia,27NH2@186928|unclassified Lachnospiraceae	186801|Clostridia	L	RAMP superfamily	-	-	-	-	-	-	-	-	-	-	-	-	RAMPs
NFNHFNFO_00848	397291.C804_01796	1.05e-109	342.0	COG1337@1|root,COG1337@2|Bacteria,1VB9Y@1239|Firmicutes,24KU1@186801|Clostridia	186801|Clostridia	L	RAMP superfamily	-	-	-	ko:K19134	-	-	-	-	ko00000,ko02048	-	-	-	RAMPs
NFNHFNFO_00849	397291.C804_01795	1.15e-54	179.0	COG1337@1|root,COG1337@2|Bacteria,1VEYV@1239|Firmicutes	1239|Firmicutes	L	RAMP superfamily	-	-	-	-	-	-	-	-	-	-	-	-	RAMPs
NFNHFNFO_00850	1408311.JNJM01000019_gene1872	1.16e-142	427.0	COG1353@1|root,COG1353@2|Bacteria,1UZM3@1239|Firmicutes,24KWD@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00851	500632.CLONEX_02806	2.46e-105	311.0	COG1737@1|root,COG1737@2|Bacteria,1TS9A@1239|Firmicutes,24HCX@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NFNHFNFO_00852	1226325.HMPREF1548_03116	4.38e-87	262.0	COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,24B0N@186801|Clostridia,36FGH@31979|Clostridiaceae	186801|Clostridia	S	Maltose acetyltransferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
NFNHFNFO_00853	1235792.C808_02122	3.46e-79	243.0	COG0546@1|root,COG0546@2|Bacteria,1V9Z4@1239|Firmicutes,24QFD@186801|Clostridia	186801|Clostridia	S	TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 1 with third motif having Dx(3-4)D or Dx(3-4)E	-	-	3.6.1.1	ko:K06019	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	HAD_2
NFNHFNFO_00854	33035.JPJF01000032_gene2149	0.0	1571.0	COG0426@1|root,COG1251@1|root,COG0426@2|Bacteria,COG1251@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3XZNS@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	fprA2	-	1.6.3.4	ko:K22405	-	-	-	-	ko00000,ko01000	-	-	-	Flavodoxin_1,Lactamase_B,Pyr_redox_2
NFNHFNFO_00855	33035.JPJF01000032_gene2151	3.81e-171	495.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,3XZ4Y@572511|Blautia	186801|Clostridia	M	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
NFNHFNFO_00856	33035.JPJF01000032_gene2152	3.45e-201	572.0	COG0791@1|root,COG3883@1|root,COG0791@2|Bacteria,COG3883@2|Bacteria,1UVYK@1239|Firmicutes,249G6@186801|Clostridia,3XZ4Y@572511|Blautia	186801|Clostridia	M	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	NLPC_P60
NFNHFNFO_00857	33035.JPJF01000032_gene2153	0.0	951.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,3XYPP@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
NFNHFNFO_00858	33035.JPJF01000032_gene2154	4.59e-88	259.0	COG4747@1|root,COG4747@2|Bacteria,1V4AA@1239|Firmicutes,2593P@186801|Clostridia,3Y1XD@572511|Blautia	186801|Clostridia	S	ACT domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00859	33035.JPJF01000032_gene2155	4.75e-126	359.0	COG1014@1|root,COG1014@2|Bacteria,1V1DT@1239|Firmicutes,24HIC@186801|Clostridia,3Y05Y@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	iorB	-	1.2.7.8	ko:K00180	-	-	-	-	br01601,ko00000,ko01000	-	-	-	POR
NFNHFNFO_00860	33035.JPJF01000032_gene2156	0.0	1119.0	COG4231@1|root,COG4231@2|Bacteria,1TNY3@1239|Firmicutes,247U1@186801|Clostridia,3XYPI@572511|Blautia	186801|Clostridia	C	oxidoreductase subunit alpha	iorA	-	1.2.7.8	ko:K00179	-	-	-	-	br01601,ko00000,ko01000	-	-	-	Fer4,POR_N,TPP_enzyme_C
NFNHFNFO_00861	33035.JPJF01000032_gene2157	5.87e-313	852.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,3Y0PX@572511|Blautia	186801|Clostridia	H	AMP-binding enzyme	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
NFNHFNFO_00862	33035.JPJF01000032_gene2158	1.06e-70	215.0	2E5GB@1|root,33080@2|Bacteria,1VF18@1239|Firmicutes,24R5R@186801|Clostridia,3Y0IK@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	CorC_HlyC
NFNHFNFO_00863	742733.HMPREF9469_01397	1.93e-170	497.0	COG2865@1|root,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,2208Y@1506553|Lachnoclostridium	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
NFNHFNFO_00864	33035.JPJF01000032_gene2160	0.0	899.0	COG1113@1|root,COG1113@2|Bacteria,1UHVM@1239|Firmicutes	1239|Firmicutes	E	amino acid	-	-	-	ko:K03294,ko:K11737	-	-	-	-	ko00000,ko02000	2.A.3.1.7,2.A.3.2	-	-	AA_permease_2
NFNHFNFO_00865	33035.JPJF01000032_gene2161	1.31e-286	785.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,3XZ14@572511|Blautia	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_1_2,Histidinol_dh
NFNHFNFO_00866	33035.JPJF01000032_gene2162	5.09e-268	737.0	COG0789@1|root,COG0789@2|Bacteria,1V12J@1239|Firmicutes,24DI4@186801|Clostridia	186801|Clostridia	K	regulatory protein MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_25,Methyltransf_31
NFNHFNFO_00867	1449050.JNLE01000005_gene5173	3.96e-85	256.0	COG1476@1|root,COG1476@2|Bacteria,1V7I5@1239|Firmicutes,24KRY@186801|Clostridia,36J6U@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_00868	1506994.JNLQ01000003_gene3783	1.97e-133	395.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24BP7@186801|Clostridia,4BXX1@830|Butyrivibrio	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
NFNHFNFO_00869	33035.JPJF01000008_gene1190	9.9e-26	104.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	yagG	-	-	ko:K03292,ko:K05820	-	-	-	-	ko00000,ko02000	2.A.1.27,2.A.2	-	-	MFS_2
NFNHFNFO_00870	33035.JPJF01000032_gene2163	1.09e-209	581.0	COG0657@1|root,COG0657@2|Bacteria,1V1UH@1239|Firmicutes,248MF@186801|Clostridia,3Y1Q0@572511|Blautia	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
NFNHFNFO_00871	33035.JPJF01000008_gene1188	3.79e-255	737.0	COG2207@1|root,COG3664@1|root,COG2207@2|Bacteria,COG3664@2|Bacteria,1TQGI@1239|Firmicutes,2490Q@186801|Clostridia,3Y206@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 39	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Glyco_hydro_39,HTH_18
NFNHFNFO_00874	33035.JPJF01000032_gene2164	2.82e-298	814.0	COG1362@1|root,COG1362@2|Bacteria,1TQ3Z@1239|Firmicutes,248UP@186801|Clostridia,3XYMU@572511|Blautia	186801|Clostridia	E	M18 family aminopeptidase	apeB	-	3.4.11.21	ko:K01267	-	-	-	-	ko00000,ko01000,ko01002,ko04131	-	-	-	Peptidase_M18
NFNHFNFO_00875	33035.JPJF01000032_gene2165	0.0	882.0	COG0531@1|root,COG0531@2|Bacteria,1TRFS@1239|Firmicutes,248WW@186801|Clostridia,3Y0YC@572511|Blautia	186801|Clostridia	E	Amino acid permease	NPD5_3681	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
NFNHFNFO_00876	33035.JPJF01000032_gene2166	0.0	1468.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3XYHY@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	xdhD	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
NFNHFNFO_00877	33035.JPJF01000032_gene2167	1.43e-105	305.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24HQN@186801|Clostridia,3XZVY@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	hcrC	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
NFNHFNFO_00878	33035.JPJF01000032_gene2168	9.67e-168	472.0	COG1319@1|root,COG1319@2|Bacteria,1TSNH@1239|Firmicutes,24A57@186801|Clostridia,3XZ2J@572511|Blautia	186801|Clostridia	C	COG COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
NFNHFNFO_00879	33035.JPJF01000032_gene2169	2.3e-205	573.0	COG2367@1|root,COG2367@2|Bacteria,1VHF8@1239|Firmicutes	1239|Firmicutes	V	Beta-lactamase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase2
NFNHFNFO_00880	33035.JPJF01000032_gene2170	3.1e-305	835.0	COG0534@1|root,COG0534@2|Bacteria,1TRR0@1239|Firmicutes,249UC@186801|Clostridia,3XZB1@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_00881	33035.JPJF01000032_gene2171	1.74e-138	393.0	COG3103@1|root,COG3103@2|Bacteria,1US8A@1239|Firmicutes,25A7D@186801|Clostridia,3Y1R5@572511|Blautia	186801|Clostridia	T	Bacterial SH3 domain homologues	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
NFNHFNFO_00882	33035.JPJF01000032_gene2177	1.62e-169	474.0	COG1691@1|root,COG1691@2|Bacteria,1TP0Z@1239|Firmicutes,24815@186801|Clostridia,3XZ2M@572511|Blautia	186801|Clostridia	S	AIR carboxylase	-	-	-	ko:K06898	-	-	-	-	ko00000	-	-	-	AIRC
NFNHFNFO_00883	33035.JPJF01000032_gene2178	2.75e-245	673.0	COG2502@1|root,COG2502@2|Bacteria,1TP28@1239|Firmicutes,248S4@186801|Clostridia,3XYZ8@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	asnA	-	6.3.1.1	ko:K01914	ko00250,ko00460,ko01100,ko01110,ko01230,map00250,map00460,map01100,map01110,map01230	-	R00483	RC00010	ko00000,ko00001,ko01000	-	-	-	AsnA
NFNHFNFO_00884	33035.JPJF01000032_gene2179	3.19e-295	810.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,2481G@186801|Clostridia,3XYVW@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_00885	33035.JPJF01000032_gene2180	0.0	1006.0	COG3534@1|root,COG3534@2|Bacteria,1TRY9@1239|Firmicutes,2497J@186801|Clostridia,3Y1AY@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	abfA	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
NFNHFNFO_00886	33035.JPJF01000032_gene2181	1.24e-196	546.0	COG0395@1|root,COG0395@2|Bacteria,1TT5G@1239|Firmicutes,249MU@186801|Clostridia,3Y17N@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17236	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
NFNHFNFO_00887	33035.JPJF01000032_gene2182	2.35e-211	584.0	COG1175@1|root,COG1175@2|Bacteria,1TRSP@1239|Firmicutes,24906@186801|Clostridia,3Y17F@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17235	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
NFNHFNFO_00888	33035.JPJF01000032_gene2183	0.0	889.0	COG1653@1|root,COG1653@2|Bacteria,1TS9Z@1239|Firmicutes,2490T@186801|Clostridia	186801|Clostridia	G	Extracellular solute-binding protein	araN	-	-	ko:K17234	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_00889	33035.JPJF01000032_gene2184	0.0	1242.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia,3Y0XI@572511|Blautia	186801|Clostridia	S	Beta-L-arabinofuranosidase, GH127	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
NFNHFNFO_00891	33035.JPJF01000032_gene2185	1.32e-245	676.0	COG1609@1|root,COG1609@2|Bacteria,1TRWK@1239|Firmicutes,24DAV@186801|Clostridia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_00892	33035.JPJF01000016_gene4136	4.14e-243	671.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XYK4@572511|Blautia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
NFNHFNFO_00893	33035.JPJF01000016_gene4137	3.1e-251	692.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XYK4@572511|Blautia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran
NFNHFNFO_00894	33035.JPJF01000016_gene4138	6.89e-194	538.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3Y2ED@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_00895	33035.JPJF01000016_gene4139	7.52e-210	581.0	COG1175@1|root,COG1175@2|Bacteria,1UYKA@1239|Firmicutes,24FGT@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_00896	33035.JPJF01000016_gene4140	0.0	908.0	COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,25MFQ@186801|Clostridia,3Y1RK@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
NFNHFNFO_00897	33035.JPJF01000016_gene4141	1.28e-184	514.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia,3Y1RX@572511|Blautia	186801|Clostridia	K	DeoR C terminal sensor domain	-	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
NFNHFNFO_00898	33035.JPJF01000016_gene4142	3.2e-181	507.0	COG3588@1|root,COG3588@2|Bacteria,1TPUJ@1239|Firmicutes,24924@186801|Clostridia,3Y16B@572511|Blautia	186801|Clostridia	G	Fructose-bisphosphate aldolase class-I	fda	-	4.1.2.13	ko:K01623	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000,ko03036,ko04131,ko04147	-	-	-	Glycolytic
NFNHFNFO_00899	33035.JPJF01000016_gene4143	0.0	905.0	COG1027@1|root,COG1027@2|Bacteria,1TP3U@1239|Firmicutes,2483Z@186801|Clostridia,3Y0Z4@572511|Blautia	186801|Clostridia	E	Fumarase C C-terminus	aspA	-	4.3.1.1	ko:K01744	ko00250,ko01100,map00250,map01100	-	R00490	RC00316,RC02799	ko00000,ko00001,ko01000	-	-	-	FumaraseC_C,Lyase_1
NFNHFNFO_00900	33035.JPJF01000016_gene4144	1.85e-203	566.0	COG0583@1|root,COG0583@2|Bacteria,1UYAI@1239|Firmicutes,24BA8@186801|Clostridia,3XZQR@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_00901	33035.JPJF01000016_gene4145	9.44e-238	655.0	COG0407@1|root,COG0407@2|Bacteria,1V9U0@1239|Firmicutes	1239|Firmicutes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_00902	33035.JPJF01000016_gene4146	8.84e-291	797.0	COG2610@1|root,COG2610@2|Bacteria,1TUM6@1239|Firmicutes,25MFA@186801|Clostridia,3Y1YR@572511|Blautia	186801|Clostridia	EG	GntP family permease	-	-	-	-	-	-	-	-	-	-	-	-	GntP_permease
NFNHFNFO_00903	33035.JPJF01000016_gene4147	0.0	890.0	COG2508@1|root,COG2508@2|Bacteria,1V5QP@1239|Firmicutes,24IVE@186801|Clostridia	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NFNHFNFO_00904	33035.JPJF01000016_gene4148	7.03e-135	385.0	COG1668@1|root,COG1668@2|Bacteria,1UI0E@1239|Firmicutes,25E94@186801|Clostridia	186801|Clostridia	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
NFNHFNFO_00905	33035.JPJF01000016_gene4149	6.15e-171	480.0	COG1131@1|root,COG1131@2|Bacteria,1TRNT@1239|Firmicutes,24B5J@186801|Clostridia,3Y0Y2@572511|Blautia	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_00906	33035.JPJF01000016_gene4150	1.53e-76	232.0	2DNEV@1|root,32X5D@2|Bacteria,1VCIU@1239|Firmicutes,24SKC@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00907	33035.JPJF01000016_gene4151	3.38e-87	258.0	COG3279@1|root,COG3279@2|Bacteria,1V6EJ@1239|Firmicutes,25B1E@186801|Clostridia	186801|Clostridia	K	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR
NFNHFNFO_00908	33035.JPJF01000016_gene4152	3.83e-239	660.0	COG3049@1|root,COG3049@2|Bacteria,1UHUX@1239|Firmicutes,25E3I@186801|Clostridia	186801|Clostridia	M	Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase	-	-	-	-	-	-	-	-	-	-	-	-	AAT
NFNHFNFO_00909	33035.JPJF01000016_gene4153	2.04e-181	508.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TQKE@1239|Firmicutes,24DBB@186801|Clostridia	186801|Clostridia	K	AraC family	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like,HTH_18
NFNHFNFO_00910	33035.JPJF01000016_gene4154	0.0	911.0	COG0624@1|root,COG0624@2|Bacteria,1TRHJ@1239|Firmicutes,24DN5@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	ko:K13049	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
NFNHFNFO_00911	33035.JPJF01000016_gene4155	1.61e-146	414.0	28N4D@1|root,2ZB9V@2|Bacteria,1UPRR@1239|Firmicutes,24MJV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00912	33035.JPJF01000016_gene4156	3.64e-162	455.0	arCOG13338@1|root,2Z9XC@2|Bacteria,1UPRH@1239|Firmicutes,25HMN@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF5058)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5058
NFNHFNFO_00913	33035.JPJF01000016_gene4157	1.72e-296	814.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3XZ7G@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_00914	33035.JPJF01000016_gene4158	1.78e-107	312.0	COG0406@1|root,COG0406@2|Bacteria,1VCU1@1239|Firmicutes,24Q22@186801|Clostridia	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NFNHFNFO_00915	33035.JPJF01000016_gene4159	2.53e-140	398.0	COG0745@1|root,COG0745@2|Bacteria,1V0KM@1239|Firmicutes,24DU7@186801|Clostridia,3Y2AW@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_00916	33035.JPJF01000016_gene4160	2.43e-223	618.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,3Y000@572511|Blautia	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
NFNHFNFO_00917	33035.JPJF01000016_gene4161	7.36e-173	483.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,3XZDV@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_00918	33035.JPJF01000016_gene4162	0.0	1159.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,3Y0AT@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NFNHFNFO_00919	33035.JPJF01000016_gene4163	1.1e-164	466.0	COG0789@1|root,COG0789@2|Bacteria,1UF0K@1239|Firmicutes,256IS@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
NFNHFNFO_00921	33035.JPJF01000016_gene4166	7.51e-74	223.0	COG1595@1|root,COG1595@2|Bacteria,1V9ZH@1239|Firmicutes,25MQU@186801|Clostridia,3Y0W6@572511|Blautia	186801|Clostridia	K	RNA polymerase sigma-70 factor, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_00923	1449050.JNLE01000003_gene1595	4.52e-81	239.0	29A02@1|root,2ZX1N@2|Bacteria,1V48B@1239|Firmicutes,24HF1@186801|Clostridia,36J4Y@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00925	33035.JPJF01000016_gene4168	0.0	1557.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3Y07X@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NFNHFNFO_00926	33035.JPJF01000016_gene4169	3.45e-182	509.0	COG2207@1|root,COG2207@2|Bacteria,1V48H@1239|Firmicutes,248BW@186801|Clostridia,3XZC4@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
NFNHFNFO_00927	33035.JPJF01000016_gene4170	5.61e-227	626.0	COG1533@1|root,COG1533@2|Bacteria,1TPA3@1239|Firmicutes,249NM@186801|Clostridia	186801|Clostridia	L	Spore photoproduct lyase	-	-	4.1.99.14	ko:K03716	-	-	-	-	ko00000,ko01000	-	-	-	-
NFNHFNFO_00928	33035.JPJF01000016_gene4171	8.1e-49	155.0	2C9HP@1|root,33Z9H@2|Bacteria,1W1CU@1239|Firmicutes,25441@186801|Clostridia,3Y0HT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00929	397288.C806_03613	2.86e-81	244.0	COG0454@1|root,COG0456@2|Bacteria,1VCET@1239|Firmicutes,24MTN@186801|Clostridia,27QXV@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_00931	33035.JPJF01000016_gene4175	1.16e-153	437.0	2E7DC@1|root,331WG@2|Bacteria,1VGCF@1239|Firmicutes,24QIK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00932	33035.JPJF01000016_gene4176	6.14e-147	418.0	2E7DC@1|root,331WG@2|Bacteria,1VGCF@1239|Firmicutes,24QIK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00933	33035.JPJF01000016_gene4177	2.75e-65	199.0	2DSEA@1|root,33FSH@2|Bacteria,1VNCF@1239|Firmicutes,24W88@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00934	33035.JPJF01000016_gene4178	8.39e-194	544.0	2BDA6@1|root,326YM@2|Bacteria,1V84X@1239|Firmicutes,24JRS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	ko:K08223	-	-	-	-	ko00000,ko02000	2.A.1.35	-	-	-
NFNHFNFO_00935	33035.JPJF01000016_gene4179	2.64e-96	281.0	COG1225@1|root,COG1225@2|Bacteria,1V3N5@1239|Firmicutes,24HP8@186801|Clostridia,3XZUT@572511|Blautia	186801|Clostridia	O	Antioxidant, AhpC TSA family	bcp	-	1.11.1.15	ko:K03564	-	-	-	-	ko00000,ko01000	-	-	-	AhpC-TSA
NFNHFNFO_00936	33035.JPJF01000016_gene4180	4.87e-45	145.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia	186801|Clostridia	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
NFNHFNFO_00937	33035.JPJF01000016_gene4183	0.0	1228.0	COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,24CZV@186801|Clostridia,3Y0KK@572511|Blautia	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NFNHFNFO_00938	33035.JPJF01000016_gene4184	1.98e-192	541.0	COG1721@1|root,COG1721@2|Bacteria,1UZHY@1239|Firmicutes,24DE8@186801|Clostridia,3Y0QG@572511|Blautia	186801|Clostridia	S	conserved protein (some members contain a von Willebrand factor type A (vWA) domain)	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
NFNHFNFO_00939	33035.JPJF01000016_gene4185	5.11e-215	595.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia,3XYTD@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
NFNHFNFO_00940	33035.JPJF01000016_gene4186	1.57e-116	337.0	COG0716@1|root,COG0716@2|Bacteria,1UUUV@1239|Firmicutes,25KCS@186801|Clostridia,3Y0VS@572511|Blautia	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
NFNHFNFO_00941	33035.JPJF01000016_gene4187	6.03e-226	624.0	COG4129@1|root,COG4129@2|Bacteria,1TP2T@1239|Firmicutes,24A4H@186801|Clostridia,3Y207@572511|Blautia	186801|Clostridia	S	Putative aromatic acid exporter C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	ArAE_1,ArAE_1_C
NFNHFNFO_00942	33035.JPJF01000016_gene4188	4.21e-79	237.0	2BVD7@1|root,32QT8@2|Bacteria,1V6S8@1239|Firmicutes,257S1@186801|Clostridia,3Y0WY@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2383
NFNHFNFO_00943	33035.JPJF01000095_gene2133	7.92e-221	610.0	COG1432@1|root,COG1432@2|Bacteria,1TTAC@1239|Firmicutes,249NE@186801|Clostridia,3XZ7E@572511|Blautia	186801|Clostridia	S	NYN domain	-	-	-	-	-	-	-	-	-	-	-	-	NYN,OST-HTH
NFNHFNFO_00944	33035.JPJF01000095_gene2132	4.14e-51	167.0	2CH8U@1|root,306GF@2|Bacteria,1VDTB@1239|Firmicutes,25AZP@186801|Clostridia	186801|Clostridia	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
NFNHFNFO_00945	33035.JPJF01000095_gene2132	1.1e-46	155.0	2CH8U@1|root,306GF@2|Bacteria,1VDTB@1239|Firmicutes,25AZP@186801|Clostridia	186801|Clostridia	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
NFNHFNFO_00946	33035.JPJF01000095_gene2131	3.42e-105	305.0	COG0778@1|root,COG0778@2|Bacteria,1V3YJ@1239|Firmicutes,24BKH@186801|Clostridia,3Y1HS@572511|Blautia	186801|Clostridia	C	Nitroreductase family	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase,TM1586_NiRdase
NFNHFNFO_00948	33035.JPJF01000011_gene1265	9.64e-189	526.0	COG4974@1|root,COG4974@2|Bacteria,1TY7M@1239|Firmicutes,24BN9@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
NFNHFNFO_00949	33035.JPJF01000011_gene1266	4.08e-173	488.0	COG2169@1|root,COG2169@2|Bacteria,1UUUH@1239|Firmicutes,25KCH@186801|Clostridia,3Y21B@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_00950	33035.JPJF01000011_gene1267	1.34e-281	771.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,24AE7@186801|Clostridia,3Y0NS@572511|Blautia	186801|Clostridia	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	GO:0000287,GO:0003674,GO:0005488,GO:0043167,GO:0043169,GO:0046872	4.2.1.5,4.2.1.8	ko:K01683,ko:K08323	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
NFNHFNFO_00951	33035.JPJF01000011_gene1268	6.05e-108	311.0	COG3871@1|root,COG3871@2|Bacteria,1V49E@1239|Firmicutes,24GGN@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
NFNHFNFO_00952	33035.JPJF01000011_gene1269	5.12e-138	392.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,3XZK2@572511|Blautia	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
NFNHFNFO_00953	869209.Tresu_0522	5.36e-92	270.0	2CI1N@1|root,3025Y@2|Bacteria,2J7GV@203691|Spirochaetes	203691|Spirochaetes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00954	33035.JPJF01000011_gene1274	4.87e-235	645.0	COG1917@1|root,COG1917@2|Bacteria,1VWQR@1239|Firmicutes,24KNE@186801|Clostridia	186801|Clostridia	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NFNHFNFO_00955	33035.JPJF01000011_gene1275	3.91e-77	245.0	COG2207@1|root,COG2207@2|Bacteria,1VF9U@1239|Firmicutes,24DGF@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NFNHFNFO_00956	33035.JPJF01000011_gene1275	1.43e-188	534.0	COG2207@1|root,COG2207@2|Bacteria,1VF9U@1239|Firmicutes,24DGF@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NFNHFNFO_00957	553973.CLOHYLEM_04314	1.25e-72	241.0	2DBEW@1|root,2Z8UY@2|Bacteria,1UYFJ@1239|Firmicutes,2489J@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4874)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4832,DUF4874
NFNHFNFO_00958	1232453.BAIF02000009_gene3082	3.05e-115	343.0	COG1216@1|root,COG1216@2|Bacteria,1VATJ@1239|Firmicutes,24H9J@186801|Clostridia,268VP@186813|unclassified Clostridiales	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NFNHFNFO_00959	553973.CLOHYLEM_04316	8.53e-93	288.0	COG1216@1|root,COG1216@2|Bacteria	2|Bacteria	V	Glycosyl transferase, family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2,Glyphos_transf
NFNHFNFO_00961	553973.CLOHYLEM_04317	1.2e-116	359.0	COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,24917@186801|Clostridia,2207Y@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_3
NFNHFNFO_00962	553973.CLOHYLEM_04318	1.37e-194	556.0	COG4267@1|root,COG4267@2|Bacteria,1TRZE@1239|Firmicutes,24EQ7@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K21012	ko02025,map02025	-	-	-	ko00000,ko00001	-	-	-	PelG
NFNHFNFO_00963	1232453.BAIF02000009_gene3077	2.6e-248	692.0	COG0438@1|root,COG0438@2|Bacteria,1TQ8U@1239|Firmicutes,24BAM@186801|Clostridia,268AM@186813|unclassified Clostridiales	186801|Clostridia	M	Domain of unknown function (DUF3492)	-	-	-	ko:K21011	ko02025,map02025	-	-	-	ko00000,ko00001,ko01003	-	GT4	-	DUF3492,Glycos_transf_1
NFNHFNFO_00964	553973.CLOHYLEM_04320	1.89e-88	290.0	28HJQ@1|root,2Z7UU@2|Bacteria,1UPMJ@1239|Firmicutes,24BW1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF2194
NFNHFNFO_00965	556261.HMPREF0240_03378	1.56e-81	251.0	COG1216@1|root,COG1216@2|Bacteria,1UAQP@1239|Firmicutes,25B5D@186801|Clostridia,36WAM@31979|Clostridiaceae	186801|Clostridia	S	Glycosyl transferase family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NFNHFNFO_00966	556261.HMPREF0240_03377	1.4e-182	546.0	28N1Z@1|root,2ZB7X@2|Bacteria,1UZID@1239|Firmicutes,24F7M@186801|Clostridia,36JXG@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00968	556261.HMPREF0240_03375	1.57e-160	487.0	COG0451@1|root,COG0451@2|Bacteria,1UYUX@1239|Firmicutes,24CYP@186801|Clostridia,36GYR@31979|Clostridiaceae	186801|Clostridia	GM	Psort location CytoplasmicMembrane, score	-	-	5.1.3.2	ko:K01784,ko:K21009	ko00052,ko00520,ko01100,ko02025,map00052,map00520,map01100,map02025	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,RmlD_sub_bind
NFNHFNFO_00969	1232453.BAIF02000009_gene3070	1.91e-11	64.3	COG2456@1|root,COG2456@2|Bacteria,1VN5U@1239|Firmicutes,24UTR@186801|Clostridia	186801|Clostridia	S	Uncharacterized conserved protein (DUF2304)	-	-	-	ko:K09153	-	-	-	-	ko00000	-	-	-	DUF2304
NFNHFNFO_00970	658086.HMPREF0994_06179	3.81e-104	308.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24C2K@186801|Clostridia,27TAQ@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NFNHFNFO_00971	742740.HMPREF9474_02106	1.19e-149	428.0	COG5551@1|root,COG5551@2|Bacteria,1UZCQ@1239|Firmicutes,259UY@186801|Clostridia,22397@1506553|Lachnoclostridium	186801|Clostridia	S	CRISPR-associated endoribonuclease Cas6	-	-	-	-	-	-	-	-	-	-	-	-	CRISPR_Cas6
NFNHFNFO_00972	556261.HMPREF0240_01392	6.18e-69	213.0	COG0655@1|root,COG0655@2|Bacteria,1UI36@1239|Firmicutes,247R8@186801|Clostridia,36HCH@31979|Clostridiaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NFNHFNFO_00973	33035.JPJF01000011_gene1279	5.08e-49	158.0	COG0655@1|root,COG0655@2|Bacteria,1UI36@1239|Firmicutes,247R8@186801|Clostridia	186801|Clostridia	E	PFAM NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NFNHFNFO_00974	33035.JPJF01000011_gene1281	3.64e-221	610.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3XYMJ@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
NFNHFNFO_00975	33035.JPJF01000011_gene1284	1.11e-195	545.0	COG0264@1|root,COG0264@2|Bacteria,1TPFJ@1239|Firmicutes,248J2@186801|Clostridia,3XZ81@572511|Blautia	186801|Clostridia	J	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome	tsf	-	-	ko:K02357	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EF_TS
NFNHFNFO_00976	33035.JPJF01000011_gene1285	1.62e-164	461.0	COG0052@1|root,COG0052@2|Bacteria,1TPNA@1239|Firmicutes,247ZR@186801|Clostridia,3XYW8@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	rpsB	-	-	ko:K02967	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S2
NFNHFNFO_00977	33035.JPJF01000011_gene1286	1.01e-176	494.0	COG0657@1|root,COG0657@2|Bacteria,1TP1H@1239|Firmicutes,24D7F@186801|Clostridia,3XYMP@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3,Peptidase_S9
NFNHFNFO_00978	33035.JPJF01000011_gene1287	0.0	1281.0	COG3855@1|root,COG3855@2|Bacteria,1TPFU@1239|Firmicutes,248ZC@186801|Clostridia,3XZC9@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fbp	-	3.1.3.11	ko:K04041	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00165,M00167	R00762,R04780	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FBPase_2
NFNHFNFO_00979	33035.JPJF01000011_gene1288	5.02e-166	483.0	COG0841@1|root,COG0841@2|Bacteria,1UUUI@1239|Firmicutes,24UBM@186801|Clostridia	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	-	-	-	-	-	-	-	-	-	-	-	-	Big_3_2
NFNHFNFO_00980	33035.JPJF01000011_gene1289	1.49e-274	764.0	COG0515@1|root,COG0515@2|Bacteria,1TPYP@1239|Firmicutes,24ABN@186801|Clostridia,3Y0GE@572511|Blautia	186801|Clostridia	KLT	Protein kinase domain	-	-	2.7.11.1	ko:K08884,ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	Pkinase
NFNHFNFO_00981	33035.JPJF01000011_gene1290	0.0	1129.0	COG0018@1|root,COG0018@2|Bacteria,1TPEZ@1239|Firmicutes,248JZ@186801|Clostridia,3XZ10@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	argS	-	6.1.1.19	ko:K01887	ko00970,map00970	M00359,M00360	R03646	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Arg_tRNA_synt_N,DALR_1,tRNA-synt_1d
NFNHFNFO_00982	33035.JPJF01000011_gene1291	3.58e-191	533.0	COG1307@1|root,COG1307@2|Bacteria,1TRM7@1239|Firmicutes,248N9@186801|Clostridia,3XYTV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NFNHFNFO_00983	33035.JPJF01000011_gene1292	1.11e-120	347.0	COG1139@1|root,COG1139@2|Bacteria,1TP90@1239|Firmicutes,249B6@186801|Clostridia,3Y008@572511|Blautia	186801|Clostridia	C	LUD domain	-	-	-	-	-	-	-	-	-	-	-	-	LUD_dom
NFNHFNFO_00984	33035.JPJF01000011_gene1293	2.55e-261	719.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3XZ33@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NFNHFNFO_00985	33035.JPJF01000011_gene1294	0.0	999.0	COG0845@1|root,COG3266@1|root,COG0845@2|Bacteria,COG3266@2|Bacteria,1UZ3U@1239|Firmicutes,24BV7@186801|Clostridia,3XYTA@572511|Blautia	186801|Clostridia	M	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3
NFNHFNFO_00986	33035.JPJF01000011_gene1295	1.44e-228	642.0	COG0845@1|root,COG0845@2|Bacteria,1V046@1239|Firmicutes,24ANJ@186801|Clostridia,3XYZR@572511|Blautia	186801|Clostridia	M	Biotin-lipoyl like	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NFNHFNFO_00987	33035.JPJF01000011_gene1296	1.55e-72	218.0	COG0745@1|root,COG0745@2|Bacteria,1VGRV@1239|Firmicutes,24QZM@186801|Clostridia	186801|Clostridia	KT	Sporulation initiation factor Spo0A domain protein	-	-	-	ko:K07699	ko02020,ko02024,map02020,map02024	M00485	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Spo0A_C
NFNHFNFO_00988	394503.Ccel_3225	4.95e-110	328.0	COG0524@1|root,COG0524@2|Bacteria,1TQRC@1239|Firmicutes,249QQ@186801|Clostridia,36G1Q@31979|Clostridiaceae	186801|Clostridia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	rbsK	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NFNHFNFO_00989	180332.JTGN01000018_gene55	5.17e-115	339.0	COG0395@1|root,COG0395@2|Bacteria,1UCH2@1239|Firmicutes,24AS5@186801|Clostridia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_00990	180332.JTGN01000018_gene54	8.48e-104	312.0	COG1175@1|root,COG1175@2|Bacteria,1V2TM@1239|Firmicutes,24H6J@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_00991	180332.JTGN01000018_gene53	7.17e-161	470.0	COG1653@1|root,COG1653@2|Bacteria,1TR8U@1239|Firmicutes,25E8A@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_00992	537007.BLAHAN_04550	3.93e-153	439.0	COG1957@1|root,COG1957@2|Bacteria,1TSSS@1239|Firmicutes,24A4D@186801|Clostridia,3XZBK@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	-	-	3.2.2.1	ko:K01239	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
NFNHFNFO_00993	1226325.HMPREF1548_03069	2.27e-149	429.0	COG1957@1|root,COG1957@2|Bacteria,1UG03@1239|Firmicutes,24CXS@186801|Clostridia,36GQ0@31979|Clostridiaceae	186801|Clostridia	F	Psort location Cytoplasmic, score 7.50	-	-	-	-	-	-	-	-	-	-	-	-	IU_nuc_hydro
NFNHFNFO_00994	742723.HMPREF9477_01712	5.42e-130	380.0	COG1957@1|root,COG1957@2|Bacteria,1TRQQ@1239|Firmicutes,25C8Y@186801|Clostridia,27U3T@186928|unclassified Lachnospiraceae	186801|Clostridia	F	Inosine-uridine preferring nucleoside hydrolase	iunH	-	3.2.2.1	ko:K01239,ko:K12700	ko00230,ko00760,ko01100,map00230,map00760,map01100	-	R01245,R01273,R01677,R01770,R02143	RC00033,RC00063,RC00122,RC00318,RC00485	ko00000,ko00001,ko01000	-	-	-	IU_nuc_hydro
NFNHFNFO_00995	33035.JPJF01000011_gene1304	0.0	1173.0	COG0524@1|root,COG1609@1|root,COG0524@2|Bacteria,COG1609@2|Bacteria,1TQRC@1239|Firmicutes,24BCQ@186801|Clostridia,3XYK9@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway	-	-	2.7.1.15	ko:K00852	ko00030,map00030	-	R01051,R02750	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	LacI,Peripla_BP_3,PfkB
NFNHFNFO_00996	33035.JPJF01000011_gene1305	2.09e-219	610.0	2F32Z@1|root,33VY0@2|Bacteria,1VRWP@1239|Firmicutes,25PV9@186801|Clostridia,3XZBM@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_00998	1235798.C817_03892	1.6e-16	74.3	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia	186801|Clostridia	Q	Methyltransferase, YaeB	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
NFNHFNFO_01000	1121938.AUDY01000008_gene858	3.35e-55	193.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,3NDCQ@45667|Halobacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458,ko:K14660	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iSB619.SA_RS04785	Ketoacyl-synt_C,ketoacyl-synt
NFNHFNFO_01001	273068.TTE0142	7.36e-45	160.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,42F18@68295|Thermoanaerobacterales	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
NFNHFNFO_01002	1280682.AUKA01000001_gene1480	9.43e-140	404.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,248JG@186801|Clostridia,4BX89@830|Butyrivibrio	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HhH-GPD,Transposase_20
NFNHFNFO_01003	1280682.AUKA01000001_gene1480	6.66e-37	135.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,248JG@186801|Clostridia,4BX89@830|Butyrivibrio	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HhH-GPD,Transposase_20
NFNHFNFO_01005	981383.AEWH01000071_gene1061	3.45e-32	137.0	COG1132@1|root,COG1132@2|Bacteria,1UZA0@1239|Firmicutes,4HC2E@91061|Bacilli	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
NFNHFNFO_01006	981383.AEWH01000071_gene1062	1.59e-94	307.0	COG1132@1|root,COG1132@2|Bacteria,1TRCZ@1239|Firmicutes,4HCDT@91061|Bacilli	91061|Bacilli	V	ABC transporter transmembrane region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_membrane,ABC_tran
NFNHFNFO_01007	1034769.KB910518_gene5399	2.36e-72	233.0	COG1244@1|root,COG1244@2|Bacteria	2|Bacteria	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	ko:K06936	-	-	-	-	ko00000	-	-	-	-
NFNHFNFO_01008	931276.Cspa_c29240	2.33e-29	116.0	COG2091@1|root,COG2091@2|Bacteria,1VEYZ@1239|Firmicutes,24RQ3@186801|Clostridia,36JXF@31979|Clostridiaceae	186801|Clostridia	H	Belongs to the P-Pant transferase superfamily	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
NFNHFNFO_01009	316067.Geob_2948	1.1e-128	400.0	COG0367@1|root,COG0367@2|Bacteria,1MW4E@1224|Proteobacteria,42MEI@68525|delta/epsilon subdivisions,2WJEG@28221|Deltaproteobacteria	28221|Deltaproteobacteria	E	TIGRFAM asparagine synthase (glutamine-hydrolyzing)	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
NFNHFNFO_01010	445973.CLOBAR_00946	9.23e-66	211.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,25R8Y@186804|Peptostreptococcaceae	186801|Clostridia	IQ	3-oxoacyl- acyl-carrier-protein reductase	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
NFNHFNFO_01012	1005090.BAKON_239	4.23e-16	77.8	COG0764@1|root,COG0764@2|Bacteria,1RH2T@1224|Proteobacteria,1S63E@1236|Gammaproteobacteria,37DAW@32199|Buchnera	1236|Gammaproteobacteria	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0008693,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019171,GO:0019752,GO:0032787,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0047451,GO:0071704,GO:0072330,GO:1901576	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	iJN746.PP_1602	FabA
NFNHFNFO_01013	425104.Ssed_1853	9.31e-06	49.7	COG0824@1|root,COG0824@2|Bacteria,1MZH6@1224|Proteobacteria,1S93F@1236|Gammaproteobacteria,2QBY4@267890|Shewanellaceae	1236|Gammaproteobacteria	S	PFAM thioesterase superfamily protein	ybgC	GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0016790	3.1.2.23	ko:K01075,ko:K07107	ko00130,ko00362,ko01100,ko01110,ko01120,map00130,map00362,map01100,map01110,map01120	-	R01301	RC00004,RC00174	ko00000,ko00001,ko01000	-	-	iECP_1309.ECP_0747,iSDY_1059.SDY_0684	4HBT
NFNHFNFO_01014	935837.JAEK01000008_gene3474	3.71e-80	259.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,4H9SD@91061|Bacilli,1ZD02@1386|Bacillus	91061|Bacilli	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	-	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
NFNHFNFO_01015	697284.ERIC2_c09180	2.41e-07	51.6	COG0236@1|root,COG0236@2|Bacteria,1VYHZ@1239|Firmicutes,4HXZD@91061|Bacilli	91061|Bacilli	IQ	acyl carrier protein	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NFNHFNFO_01016	755731.Clo1100_0883	0.000606	42.4	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	-	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NFNHFNFO_01017	1304866.K413DRAFT_1776	9.99e-71	240.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,36FW3@31979|Clostridiaceae	186801|Clostridia	IQ	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding,AMP-binding_C
NFNHFNFO_01018	1230342.CTM_09536	3.9e-94	301.0	COG0318@1|root,COG0318@2|Bacteria,1TPSX@1239|Firmicutes,248JC@186801|Clostridia,36FW3@31979|Clostridiaceae	186801|Clostridia	IQ	AMP-binding enzyme	fadD	-	-	-	-	-	-	-	-	-	-	-	AMP-binding,AMP-binding_C
NFNHFNFO_01019	933262.AXAM01000037_gene877	2.39e-65	216.0	COG0037@1|root,COG0037@2|Bacteria,1NKHX@1224|Proteobacteria,42Q26@68525|delta/epsilon subdivisions,2WPER@28221|Deltaproteobacteria,2MM4H@213118|Desulfobacterales	28221|Deltaproteobacteria	D	TIGRFAM N-acetyl sugar amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01020	933262.AXAM01000037_gene876	2.51e-22	89.0	COG0236@1|root,COG0236@2|Bacteria,1NC80@1224|Proteobacteria,42VU0@68525|delta/epsilon subdivisions,2WRU6@28221|Deltaproteobacteria,2MP8W@213118|Desulfobacterales	28221|Deltaproteobacteria	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
NFNHFNFO_01021	1256908.HMPREF0373_00174	3.51e-197	598.0	COG4932@1|root,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,2492K@186801|Clostridia,25VZ7@186806|Eubacteriaceae	186801|Clostridia	M	Cna protein B-type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
NFNHFNFO_01022	1256908.HMPREF0373_00174	3.93e-191	581.0	COG4932@1|root,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,2492K@186801|Clostridia,25VZ7@186806|Eubacteriaceae	186801|Clostridia	M	Cna protein B-type domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
NFNHFNFO_01023	742723.HMPREF9477_00355	3.11e-183	513.0	COG2801@1|root,COG2801@2|Bacteria,1TU21@1239|Firmicutes,24DGQ@186801|Clostridia,27M0Q@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Integrase core domain	-	-	-	ko:K07497	-	-	-	-	ko00000	-	-	-	HTH_21,rve,rve_3
NFNHFNFO_01024	411470.RUMGNA_01471	4.32e-58	180.0	COG2963@1|root,COG2963@2|Bacteria,1VCC9@1239|Firmicutes,24NYR@186801|Clostridia,3Y1WG@572511|Blautia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Tnp_1
NFNHFNFO_01028	556261.HMPREF0240_01469	2.25e-188	534.0	COG0438@1|root,COG0438@2|Bacteria,1UBCE@1239|Firmicutes,24DYC@186801|Clostridia	186801|Clostridia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
NFNHFNFO_01029	1540257.JQMW01000011_gene1682	8.66e-66	204.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,36N1H@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NFNHFNFO_01030	1123075.AUDP01000022_gene3621	1.53e-244	694.0	COG4905@1|root,COG5523@1|root,COG4905@2|Bacteria,COG5523@2|Bacteria,1TQHG@1239|Firmicutes,2485W@186801|Clostridia,3WP0S@541000|Ruminococcaceae	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB,DUF975
NFNHFNFO_01031	33035.JPJF01000055_gene1702	4.6e-284	785.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia,3Y0TG@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
NFNHFNFO_01032	180332.JTGN01000005_gene2972	5.57e-294	811.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 43 family	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
NFNHFNFO_01033	180332.JTGN01000005_gene2973	7.58e-175	491.0	COG0395@1|root,COG0395@2|Bacteria,1TRUD@1239|Firmicutes,24CGW@186801|Clostridia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_01034	180332.JTGN01000005_gene2974	9.09e-164	462.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
NFNHFNFO_01035	180332.JTGN01000005_gene2975	1.57e-231	643.0	COG1653@1|root,COG1653@2|Bacteria,1V10D@1239|Firmicutes,24EK2@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
NFNHFNFO_01036	180332.JTGN01000005_gene2977	3.49e-207	578.0	COG1609@1|root,COG1609@2|Bacteria,1UYM8@1239|Firmicutes,24BYD@186801|Clostridia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_01037	33035.JPJF01000049_gene610	2.61e-195	545.0	COG0530@1|root,COG0530@2|Bacteria,1TRX0@1239|Firmicutes,24ABZ@186801|Clostridia,3XZSP@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07301	-	-	-	-	ko00000,ko02000	2.A.19.5	-	-	Na_Ca_ex
NFNHFNFO_01038	33035.JPJF01000049_gene609	0.0	1376.0	COG0674@1|root,COG1013@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	-	-	1.2.7.1	ko:K00169,ko:K00170	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N,TPP_enzyme_C
NFNHFNFO_01039	33035.JPJF01000049_gene608	1.05e-250	689.0	COG1014@1|root,COG1144@1|root,COG1014@2|Bacteria,COG1144@2|Bacteria,1TRFJ@1239|Firmicutes,24A29@186801|Clostridia	186801|Clostridia	C	oxidoreductase gamma subunit	-	-	1.2.7.1	ko:K00172	ko00010,ko00020,ko00620,ko00633,ko00640,ko00650,ko00680,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00633,map00640,map00650,map00680,map00720,map01100,map01120,map01130,map01200	M00173,M00307,M00374,M00620	R01196,R01199,R08034	RC00004,RC00250,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_4,POR
NFNHFNFO_01040	33035.JPJF01000049_gene607	6.34e-81	240.0	COG2033@1|root,COG2033@2|Bacteria,1VA34@1239|Firmicutes,24J9I@186801|Clostridia,3Y225@572511|Blautia	186801|Clostridia	C	Desulfoferrodoxin	-	-	1.15.1.2	ko:K05919	-	-	-	-	ko00000,ko01000	-	-	-	Desulfoferrod_N,Desulfoferrodox
NFNHFNFO_01041	33035.JPJF01000049_gene606	1.66e-179	508.0	COG4552@1|root,COG4552@2|Bacteria,1V7PR@1239|Firmicutes,24A86@186801|Clostridia,3Y090@572511|Blautia	186801|Clostridia	S	acetyltransferase involved in intracellular survival and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_9,SCP2_2
NFNHFNFO_01042	33035.JPJF01000049_gene605	7.84e-217	599.0	COG4866@1|root,COG4866@2|Bacteria,1TR2J@1239|Firmicutes,2480E@186801|Clostridia,3Y0CU@572511|Blautia	186801|Clostridia	S	Uncharacterised conserved protein (DUF2156)	-	-	-	ko:K01163	-	-	-	-	ko00000	-	-	-	DUF2156
NFNHFNFO_01043	33035.JPJF01000049_gene604	3.91e-245	673.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,25KD4@186801|Clostridia,3Y1KW@572511|Blautia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NFNHFNFO_01044	33035.JPJF01000049_gene603	0.0	1789.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG2202@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3Y1DS@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg,SnoaL_3
NFNHFNFO_01045	1232447.BAHW02000049_gene3022	1.22e-263	730.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	gph	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_01046	33035.JPJF01000098_gene1762	2.65e-217	600.0	COG1082@1|root,COG1082@2|Bacteria,1UZXE@1239|Firmicutes,24ECM@186801|Clostridia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NFNHFNFO_01047	1232447.BAHW02000049_gene3020	4.68e-261	717.0	COG0673@1|root,COG0673@2|Bacteria,1UZEK@1239|Firmicutes,24AR9@186801|Clostridia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_01048	1232447.BAHW02000049_gene3019	3.41e-205	569.0	COG1082@1|root,COG1082@2|Bacteria,1VCQ8@1239|Firmicutes,24YST@186801|Clostridia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NFNHFNFO_01049	1232447.BAHW02000049_gene3017	2.85e-129	376.0	COG2207@1|root,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
NFNHFNFO_01050	33035.JPJF01000049_gene602	2.24e-198	549.0	COG0235@1|root,COG0235@2|Bacteria,1TRMG@1239|Firmicutes,24BBT@186801|Clostridia,3XZSF@572511|Blautia	186801|Clostridia	G	Class II Aldolase and Adducin N-terminal domain	rhaD	-	4.1.2.19	ko:K01629	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01785,R02263	RC00438,RC00599,RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
NFNHFNFO_01051	33035.JPJF01000049_gene601	2.83e-300	819.0	COG4806@1|root,COG4806@2|Bacteria,1TS42@1239|Firmicutes,2487G@186801|Clostridia,3Y1E8@572511|Blautia	186801|Clostridia	G	L-rhamnose isomerase (RhaA)	rhaA	-	5.3.1.14	ko:K01813	ko00051,ko01120,map00051,map01120	-	R02437	RC00434	ko00000,ko00001,ko01000	-	-	-	RhaA
NFNHFNFO_01052	33035.JPJF01000049_gene600	3.19e-290	798.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,3XYNN@572511|Blautia	186801|Clostridia	H	FGGY family of carbohydrate kinases, C-terminal domain	rhaB	-	2.7.1.5	ko:K00848	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_01053	33035.JPJF01000049_gene599	1.93e-219	607.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1TS6T@1239|Firmicutes,247QK@186801|Clostridia,3XZK6@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
NFNHFNFO_01054	33035.JPJF01000049_gene598	3.86e-239	659.0	COG3437@1|root,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia	186801|Clostridia	T	Response regulator containing a CheY-like receiver domain and an HD-GYP domain	-	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GGDEF,HD,HD_5,Response_reg
NFNHFNFO_01055	33035.JPJF01000049_gene597	1.63e-192	535.0	COG1307@1|root,COG1307@2|Bacteria,1TQDI@1239|Firmicutes,24ADT@186801|Clostridia,3XZ39@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NFNHFNFO_01056	33035.JPJF01000049_gene596	2.49e-259	713.0	COG0793@1|root,COG0793@2|Bacteria,1TPBI@1239|Firmicutes,248HZ@186801|Clostridia,3XZBV@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S41A family	ctpA	-	3.4.21.102	ko:K03797	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_S41
NFNHFNFO_01057	33035.JPJF01000049_gene595	3.64e-172	484.0	COG2177@1|root,COG2177@2|Bacteria,1TPND@1239|Firmicutes,24AA6@186801|Clostridia,3XZN5@572511|Blautia	186801|Clostridia	D	Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation	ftsX	-	-	ko:K09811	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	FtsX
NFNHFNFO_01058	33035.JPJF01000049_gene594	1.96e-155	437.0	COG2884@1|root,COG2884@2|Bacteria,1TP58@1239|Firmicutes,248HW@186801|Clostridia,3XYQ6@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	ftsE	-	-	ko:K09812	ko02010,map02010	M00256	-	-	ko00000,ko00001,ko00002,ko02000,ko03036	3.A.1.140	-	-	ABC_tran
NFNHFNFO_01059	33035.JPJF01000049_gene593	7.37e-256	702.0	COG2508@1|root,COG2508@2|Bacteria,1TTA0@1239|Firmicutes,248HN@186801|Clostridia,3XYND@572511|Blautia	186801|Clostridia	QT	Psort location Cytoplasmic, score 8.87	cdaR_3	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
NFNHFNFO_01060	33035.JPJF01000049_gene592	4.7e-194	540.0	COG1284@1|root,COG1284@2|Bacteria,1TR9J@1239|Firmicutes,25CBM@186801|Clostridia,3Y2EM@572511|Blautia	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NFNHFNFO_01061	33035.JPJF01000049_gene591	5.49e-150	424.0	COG1922@1|root,COG1922@2|Bacteria,1V7RM@1239|Firmicutes,24HC8@186801|Clostridia,3Y0VT@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	2.4.1.187	ko:K05946	ko05111,map05111	-	-	-	ko00000,ko00001,ko01000,ko01003	-	GT26	-	Glyco_tran_WecB
NFNHFNFO_01062	33035.JPJF01000049_gene590	2.75e-206	574.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,3Y086@572511|Blautia	186801|Clostridia	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DLH,FSH1,Hydrolase_4
NFNHFNFO_01063	33035.JPJF01000049_gene589	2.02e-199	555.0	COG0714@1|root,COG0714@2|Bacteria,1TPKR@1239|Firmicutes,248IM@186801|Clostridia,3XYTD@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03924	-	-	-	-	ko00000,ko01000	-	-	-	AAA_3
NFNHFNFO_01064	33035.JPJF01000049_gene588	4.07e-231	639.0	COG1721@1|root,COG1721@2|Bacteria,1VA48@1239|Firmicutes,24CY3@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF58	-	-	-	-	-	-	-	-	-	-	-	-	DUF58
NFNHFNFO_01065	33035.JPJF01000049_gene587	0.0	1005.0	COG1305@1|root,COG1305@2|Bacteria,1TP8K@1239|Firmicutes,24CZV@186801|Clostridia	186801|Clostridia	E	Transglutaminase-like	-	-	-	-	-	-	-	-	-	-	-	-	DUF4129,Transglut_core
NFNHFNFO_01066	33035.JPJF01000049_gene585	1.19e-143	405.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3XZP9@572511|Blautia	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
NFNHFNFO_01068	33035.JPJF01000049_gene584	1.03e-171	509.0	COG0642@1|root,COG0834@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,3Y102@572511|Blautia	186801|Clostridia	T	Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
NFNHFNFO_01069	33035.JPJF01000049_gene584	2.55e-149	448.0	COG0642@1|root,COG0834@1|root,COG0642@2|Bacteria,COG0834@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,3Y102@572511|Blautia	186801|Clostridia	T	Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
NFNHFNFO_01070	33035.JPJF01000049_gene583	1.87e-252	695.0	COG1453@1|root,COG1453@2|Bacteria,1TPBG@1239|Firmicutes,2497N@186801|Clostridia,3Y0YA@572511|Blautia	186801|Clostridia	S	4Fe-4S dicluster domain	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17
NFNHFNFO_01072	33035.JPJF01000049_gene579	0.0	1365.0	COG0642@1|root,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg
NFNHFNFO_01073	33035.JPJF01000049_gene578	4.17e-275	777.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,MCPsignal,dCache_1
NFNHFNFO_01074	457421.CBFG_00175	1.18e-92	273.0	COG1670@1|root,COG1670@2|Bacteria,1V4F3@1239|Firmicutes,24EZ6@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_3
NFNHFNFO_01076	457421.CBFG_02955	4.33e-56	185.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,249TP@186801|Clostridia,269YA@186813|unclassified Clostridiales	186801|Clostridia	S	Protein of unknown function (DUF1016)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
NFNHFNFO_01077	1121335.Clst_1825	2.55e-176	504.0	COG1697@1|root,COG1697@2|Bacteria,1UJ0Q@1239|Firmicutes,25ETG@186801|Clostridia	186801|Clostridia	L	Uncharacterized protein conserved in bacteria C-term(DUF2220)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220,DUF3322
NFNHFNFO_01078	1121335.Clst_1826	0.0	1383.0	COG4913@1|root,COG4913@2|Bacteria,1TPVZ@1239|Firmicutes,2491E@186801|Clostridia,3WPGY@541000|Ruminococcaceae	186801|Clostridia	S	DNA replication and repair protein RecF	-	-	-	-	-	-	-	-	-	-	-	-	AAA_29,SMC_hinge,SbcCD_C
NFNHFNFO_01079	1121335.Clst_1827	1.44e-105	310.0	28TNH@1|root,2ZFW0@2|Bacteria,1V32R@1239|Firmicutes,24H7Z@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4194)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4194
NFNHFNFO_01080	1121335.Clst_1828	4.31e-244	682.0	28IPI@1|root,2Z8PH@2|Bacteria,1TTBQ@1239|Firmicutes,24DMJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01081	180332.JTGN01000018_gene7	2.14e-40	142.0	COG3943@1|root,COG3943@2|Bacteria,1TPH4@1239|Firmicutes,248NI@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
NFNHFNFO_01082	1469948.JPNB01000001_gene2100	2.26e-86	265.0	COG3943@1|root,COG3943@2|Bacteria,1TPH4@1239|Firmicutes,248NI@186801|Clostridia,36ERN@31979|Clostridiaceae	186801|Clostridia	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
NFNHFNFO_01083	411902.CLOBOL_00113	1.18e-230	636.0	COG4804@1|root,COG4804@2|Bacteria,1TP7Q@1239|Firmicutes,24A19@186801|Clostridia,21ZRE@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1016
NFNHFNFO_01084	411902.CLOBOL_00114	3.01e-44	149.0	2AHGY@1|root,317UC@2|Bacteria,1V7GD@1239|Firmicutes,24P8A@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01085	33035.JPJF01000049_gene576	4.52e-263	722.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3XZS4@572511|Blautia	186801|Clostridia	J	tRNA (Uracil-5-)-methyltransferase	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
NFNHFNFO_01086	33035.JPJF01000101_gene3233	0.0	1123.0	COG4548@1|root,COG4548@2|Bacteria,1TS8V@1239|Firmicutes,249FH@186801|Clostridia,3XZDU@572511|Blautia	186801|Clostridia	P	NorD protein required for nitric oxide reductase (Nor) activity	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
NFNHFNFO_01087	33035.JPJF01000101_gene3234	4.59e-218	602.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,249C6@186801|Clostridia,3XYS0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
NFNHFNFO_01088	33035.JPJF01000101_gene3235	0.0	1371.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3XZDZ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
NFNHFNFO_01089	33035.JPJF01000101_gene3236	3.62e-118	339.0	COG1971@1|root,COG1971@2|Bacteria,1V25U@1239|Firmicutes,25CUT@186801|Clostridia,3Y0VM@572511|Blautia	186801|Clostridia	P	Putative manganese efflux pump	ytaF	-	-	-	-	-	-	-	-	-	-	-	Mntp
NFNHFNFO_01090	33035.JPJF01000101_gene3237	7.29e-215	593.0	COG1597@1|root,COG1597@2|Bacteria,1TQAU@1239|Firmicutes,249SY@186801|Clostridia,3XYYK@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	dagK	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
NFNHFNFO_01091	33035.JPJF01000101_gene3239	7.59e-113	325.0	COG0203@1|root,COG0203@2|Bacteria,1V6JQ@1239|Firmicutes,24J9T@186801|Clostridia,3XZ2H@572511|Blautia	186801|Clostridia	J	Ribosomal protein L17	rplQ	-	-	ko:K02879	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L17
NFNHFNFO_01092	537007.BLAHAN_06351	7.78e-212	587.0	COG0202@1|root,COG0202@2|Bacteria,1TPR8@1239|Firmicutes,248DS@186801|Clostridia,3XYUC@572511|Blautia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoA	-	2.7.7.6	ko:K03040	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_A_CTD,RNA_pol_A_bac,RNA_pol_L
NFNHFNFO_01093	33035.JPJF01000101_gene3241	3.33e-134	380.0	COG0522@1|root,COG0522@2|Bacteria,1TR0J@1239|Firmicutes,248Y5@186801|Clostridia,3XYWU@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit	rpsD	-	-	ko:K02986	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S4,S4
NFNHFNFO_01094	33035.JPJF01000101_gene3242	1.81e-76	229.0	COG0100@1|root,COG0100@2|Bacteria,1V3IK@1239|Firmicutes,24HIK@186801|Clostridia,3XZVK@572511|Blautia	186801|Clostridia	J	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome	rpsK	-	-	ko:K02948	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S11
NFNHFNFO_01095	33035.JPJF01000101_gene3243	1.36e-79	236.0	COG0099@1|root,COG0099@2|Bacteria,1V3JH@1239|Firmicutes,24HCT@186801|Clostridia,3Y043@572511|Blautia	186801|Clostridia	J	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits	rpsM	-	-	ko:K02952	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S13
NFNHFNFO_01096	411468.CLOSCI_02381	8.63e-128	369.0	COG0582@1|root,COG0582@2|Bacteria,1UYNW@1239|Firmicutes,24EDC@186801|Clostridia,2221A@1506553|Lachnoclostridium	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NFNHFNFO_01097	33035.JPJF01000049_gene641	0.0	1228.0	COG0556@1|root,COG0556@2|Bacteria,1TPKB@1239|Firmicutes,247P7@186801|Clostridia,3XZAR@572511|Blautia	186801|Clostridia	L	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage	uvrB	-	-	ko:K03702	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	Helicase_C,ResIII,UVR,UvrB
NFNHFNFO_01098	33035.JPJF01000049_gene642	0.0	910.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,3XYNQ@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
NFNHFNFO_01099	33035.JPJF01000049_gene643	3.18e-105	306.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3Y07M@572511|Blautia	186801|Clostridia	K	RNA polymerase sigma-70 factor, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_01100	33035.JPJF01000049_gene644	2.18e-139	410.0	2ACB9@1|root,311W7@2|Bacteria,1V49X@1239|Firmicutes,24HTT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NFNHFNFO_01101	33035.JPJF01000049_gene645	1.55e-231	639.0	COG1420@1|root,COG1420@2|Bacteria,1TQP7@1239|Firmicutes,247K2@186801|Clostridia,3XYPX@572511|Blautia	186801|Clostridia	K	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons	hrcA	-	-	ko:K03705	-	-	-	-	ko00000,ko03000	-	-	-	HrcA,HrcA_DNA-bdg
NFNHFNFO_01102	33035.JPJF01000049_gene646	3.83e-102	301.0	COG0576@1|root,COG0576@2|Bacteria,1V6G2@1239|Firmicutes,24MQK@186801|Clostridia,3XZX7@572511|Blautia	186801|Clostridia	O	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ	grpE	-	-	ko:K03687	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	GrpE
NFNHFNFO_01103	33035.JPJF01000049_gene647	0.0	1130.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia	186801|Clostridia	O	Heat shock 70 kDa protein	dnaK	-	-	ko:K04043	ko03018,ko04212,ko05152,map03018,map04212,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	1.A.33.1	-	-	HSP70
NFNHFNFO_01104	33035.JPJF01000049_gene648	6.21e-237	656.0	COG0484@1|root,COG0484@2|Bacteria,1TP00@1239|Firmicutes,248EM@186801|Clostridia,3XYJ6@572511|Blautia	186801|Clostridia	O	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins	dnaJ	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,DnaJ_C,DnaJ_CXXCXGXG
NFNHFNFO_01105	1226325.HMPREF1548_06072	4.45e-36	128.0	COG1846@1|root,COG1846@2|Bacteria,1VE9H@1239|Firmicutes,24P2B@186801|Clostridia,36KQE@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NFNHFNFO_01106	1232452.BAIB02000016_gene2403	0.0	946.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,268G3@186813|unclassified Clostridiales	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFNHFNFO_01107	1232452.BAIB02000016_gene2404	1.69e-311	861.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,268EX@186813|unclassified Clostridiales	186801|Clostridia	V	ABC transporter transmembrane region	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFNHFNFO_01108	33035.JPJF01000049_gene649	1.45e-202	565.0	COG1725@1|root,COG1725@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	ko:K07978,ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NFNHFNFO_01109	33035.JPJF01000049_gene650	3.35e-208	579.0	COG2188@1|root,COG2188@2|Bacteria,1TS1M@1239|Firmicutes,24CNY@186801|Clostridia	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
NFNHFNFO_01110	33035.JPJF01000049_gene651	0.0	1229.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3XZ8B@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NFNHFNFO_01111	33035.JPJF01000049_gene652	6.09e-310	846.0	COG0531@1|root,COG0531@2|Bacteria,1V0MG@1239|Firmicutes,25JEH@186801|Clostridia,3Y1KU@572511|Blautia	186801|Clostridia	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
NFNHFNFO_01112	478749.BRYFOR_07269	3.7e-55	183.0	COG2207@1|root,COG2207@2|Bacteria,1UYG6@1239|Firmicutes	1239|Firmicutes	K	AraC family transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NFNHFNFO_01113	478749.BRYFOR_07267	8.72e-185	527.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,248X0@186801|Clostridia	186801|Clostridia	G	solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_01114	478749.BRYFOR_07266	1.75e-138	399.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia	186801|Clostridia	P	Abc transporter, permease protein	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_01115	478749.BRYFOR_07265	2.65e-144	412.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_01116	649639.Bcell_1103	5.01e-265	752.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,4HA5R@91061|Bacilli,1ZBRR@1386|Bacillus	91061|Bacilli	G	Alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
NFNHFNFO_01117	665956.HMPREF1032_00469	4.81e-107	329.0	COG0477@1|root,COG0477@2|Bacteria,1TTC8@1239|Firmicutes,24E7T@186801|Clostridia	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	ko:K08222	-	-	-	-	ko00000,ko02000	2.A.1.33	-	-	MFS_1
NFNHFNFO_01118	33035.JPJF01000049_gene653	4.99e-185	518.0	COG0679@1|root,COG0679@2|Bacteria,1UY4N@1239|Firmicutes,24ACC@186801|Clostridia,3XZVM@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NFNHFNFO_01119	33035.JPJF01000049_gene654	2.08e-215	596.0	COG2264@1|root,COG2264@2|Bacteria,1TPKI@1239|Firmicutes,247VY@186801|Clostridia,3XZAN@572511|Blautia	186801|Clostridia	J	Ribosomal protein L11 methyltransferase	prmA	-	-	ko:K02687	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PrmA
NFNHFNFO_01120	33035.JPJF01000049_gene655	9.79e-153	431.0	COG1385@1|root,COG1385@2|Bacteria,1V1CT@1239|Firmicutes,249VK@186801|Clostridia,3XYGJ@572511|Blautia	186801|Clostridia	J	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit	rsmE	-	2.1.1.193	ko:K09761	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_RNA
NFNHFNFO_01121	33035.JPJF01000049_gene656	2.44e-250	690.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XYUM@572511|Blautia	186801|Clostridia	E	Cysteine sulfinate desulfinase cysteine desulfurase and related enzymes	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NFNHFNFO_01122	33035.JPJF01000049_gene657	3.27e-259	713.0	COG0301@1|root,COG0301@2|Bacteria,1TPNW@1239|Firmicutes,247Y5@186801|Clostridia,3XZ1T@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS	thiI	-	2.8.1.4	ko:K03151	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07461	-	ko00000,ko00001,ko01000,ko03016	-	-	-	THUMP,ThiI
NFNHFNFO_01123	33035.JPJF01000049_gene658	3.26e-48	154.0	COG1925@1|root,COG1925@2|Bacteria,1VAQP@1239|Firmicutes,24N19@186801|Clostridia,3Y0BS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NFNHFNFO_01124	33035.JPJF01000049_gene659	1.73e-289	793.0	COG0621@1|root,COG0621@2|Bacteria,1TPBR@1239|Firmicutes,247IX@186801|Clostridia,3XZ0X@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	yqeV	-	2.8.4.5	ko:K18707	-	-	R10649	RC00003,RC03221	ko00000,ko01000,ko03016	-	-	-	Radical_SAM,UPF0004
NFNHFNFO_01125	33035.JPJF01000049_gene660	6.53e-58	179.0	COG4472@1|root,COG4472@2|Bacteria,1VAC4@1239|Firmicutes,24QVQ@186801|Clostridia,3Y0G3@572511|Blautia	186801|Clostridia	S	Belongs to the UPF0297 family	yrzL	-	-	-	-	-	-	-	-	-	-	-	DUF965
NFNHFNFO_01126	33035.JPJF01000049_gene661	4.09e-96	280.0	COG0816@1|root,COG0816@2|Bacteria,1V6ER@1239|Firmicutes,24JGP@186801|Clostridia,3Y00X@572511|Blautia	186801|Clostridia	L	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA	yrrK	-	-	ko:K07447	-	-	-	-	ko00000,ko01000	-	-	-	RuvX
NFNHFNFO_01127	33035.JPJF01000049_gene662	3.24e-42	140.0	2E3Y4@1|root,32YV4@2|Bacteria,1VFRH@1239|Firmicutes,24QXW@186801|Clostridia,3Y0M4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
NFNHFNFO_01128	33035.JPJF01000049_gene663	0.0	1069.0	COG0595@1|root,COG0595@2|Bacteria,1TQ9G@1239|Firmicutes,2488J@186801|Clostridia,3XZS3@572511|Blautia	186801|Clostridia	S	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay	rnj	-	-	ko:K12574	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	Lactamase_B,Lactamase_B_2,RMMBL
NFNHFNFO_01129	33035.JPJF01000049_gene664	1.27e-72	218.0	COG3679@1|root,COG3679@2|Bacteria,1VH19@1239|Firmicutes,24RNC@186801|Clostridia,3Y0MG@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Com_YlbF
NFNHFNFO_01130	33035.JPJF01000049_gene665	1.34e-92	273.0	COG1559@1|root,COG1559@2|Bacteria,1VGA6@1239|Firmicutes,24RBR@186801|Clostridia,3Y0GT@572511|Blautia	186801|Clostridia	S	YceG-like family	-	-	-	ko:K07082	-	-	-	-	ko00000	-	-	-	YceG
NFNHFNFO_01131	33035.JPJF01000049_gene666	6.55e-135	384.0	COG4122@1|root,COG4122@2|Bacteria,1UF4M@1239|Firmicutes,24B70@186801|Clostridia,3XYN3@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yrrM	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_3
NFNHFNFO_01132	33035.JPJF01000049_gene667	3.2e-307	836.0	COG0826@1|root,COG0826@2|Bacteria,1TPRE@1239|Firmicutes,248I3@186801|Clostridia,3XYM5@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	yhbU_1	-	-	ko:K08303	ko05120,map05120	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_U32,Peptidase_U32_C
NFNHFNFO_01133	33035.JPJF01000049_gene668	5.75e-132	375.0	COG1191@1|root,COG1191@2|Bacteria,1TPJ5@1239|Firmicutes,247XH@186801|Clostridia,3XYT5@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigK	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
NFNHFNFO_01134	33035.JPJF01000049_gene669	1.15e-42	140.0	2DQDV@1|root,33675@2|Bacteria,1VITX@1239|Firmicutes,24S3U@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NFNHFNFO_01135	33035.JPJF01000049_gene670	3.26e-139	400.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (AraC family)	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_01137	33035.JPJF01000049_gene671	0.0	918.0	COG0606@1|root,COG0606@2|Bacteria,1TPPB@1239|Firmicutes,248T8@186801|Clostridia,3XYVC@572511|Blautia	186801|Clostridia	O	magnesium chelatase, subunit ChlI	comM	-	-	ko:K07391	-	-	-	-	ko00000	-	-	-	ChlI,Mg_chelatase,Mg_chelatase_C
NFNHFNFO_01138	33035.JPJF01000049_gene672	1.26e-189	529.0	COG0758@1|root,COG0758@2|Bacteria,1TPP7@1239|Firmicutes,24AS2@186801|Clostridia,3XYUB@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	dprA	-	-	ko:K04096	-	-	-	-	ko00000	-	-	-	DNA_processg_A
NFNHFNFO_01139	33035.JPJF01000049_gene673	0.0	1358.0	COG0550@1|root,COG0550@2|Bacteria,1TPUS@1239|Firmicutes,248MG@186801|Clostridia,3XZ2U@572511|Blautia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topA	-	5.99.1.2	ko:K03168	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	Topoisom_bac,Toprim,zf-C4_Topoisom
NFNHFNFO_01140	33035.JPJF01000094_gene2143	3.37e-178	497.0	COG4465@1|root,COG4465@2|Bacteria,1TS7A@1239|Firmicutes,2480R@186801|Clostridia,3XYZ9@572511|Blautia	186801|Clostridia	K	DNA-binding protein that represses the expression of many genes that are induced as cells make the transition from rapid exponential growth to stationary phase. It is a GTP-binding protein that senses the intracellular GTP concentration as an indicator of nutritional limitations. At low GTP concentration it no longer binds GTP and stop to act as a transcriptional repressor	codY	-	-	ko:K03706	-	-	-	-	ko00000,ko03000	-	-	-	CodY,HTH_CodY
NFNHFNFO_01141	33035.JPJF01000094_gene2142	1.02e-56	176.0	COG0234@1|root,COG0234@2|Bacteria,1V9ZM@1239|Firmicutes,24MMM@186801|Clostridia,3Y05R@572511|Blautia	186801|Clostridia	O	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter	groS	-	-	ko:K04078	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	Cpn10
NFNHFNFO_01142	33035.JPJF01000094_gene2141	0.0	983.0	COG0459@1|root,COG0459@2|Bacteria,1TP1T@1239|Firmicutes,248BG@186801|Clostridia,3XYV2@572511|Blautia	186801|Clostridia	O	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions	groL	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K04077	ko03018,ko04212,ko04940,ko05134,ko05152,map03018,map04212,map04940,map05134,map05152	-	-	-	ko00000,ko00001,ko03019,ko03029,ko03110,ko04147	-	-	-	Cpn60_TCP1
NFNHFNFO_01143	33035.JPJF01000094_gene2140	4e-100	292.0	2E823@1|root,332G5@2|Bacteria,1V8A8@1239|Firmicutes,24NHT@186801|Clostridia,3Y088@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01144	33035.JPJF01000094_gene2139	0.0	923.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3XZR0@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH,NMO
NFNHFNFO_01145	33035.JPJF01000094_gene2138	1.97e-149	422.0	COG5632@1|root,COG5632@2|Bacteria,1V3JT@1239|Firmicutes,24D7K@186801|Clostridia,3XZWS@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	3.5.1.28	ko:K01447	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Amidase_2
NFNHFNFO_01146	33035.JPJF01000094_gene2137	1.24e-280	778.0	COG2972@1|root,COG2972@2|Bacteria,1VS09@1239|Firmicutes,24AV3@186801|Clostridia,3Y1HV@572511|Blautia	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NFNHFNFO_01147	33035.JPJF01000024_gene3138	4.42e-165	462.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UUUY@1239|Firmicutes,25KCT@186801|Clostridia,3Y1GV@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_01148	33035.JPJF01000024_gene3139	0.0	889.0	COG1653@1|root,COG1653@2|Bacteria,1TRAX@1239|Firmicutes,2497E@186801|Clostridia,3Y0JS@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
NFNHFNFO_01149	33035.JPJF01000024_gene3140	4.02e-202	560.0	COG1175@1|root,COG1175@2|Bacteria,1UZE5@1239|Firmicutes,25MIN@186801|Clostridia,3Y15U@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_01150	33035.JPJF01000024_gene3141	1.29e-197	548.0	COG0395@1|root,COG0395@2|Bacteria,1TSM1@1239|Firmicutes,25C4V@186801|Clostridia,3Y1GS@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_01151	33035.JPJF01000024_gene3142	0.0	1397.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia,3Y2CQ@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 31	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31
NFNHFNFO_01152	33035.JPJF01000024_gene3143	0.0	1379.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 31 family	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF5110,Glyco_hydro_31
NFNHFNFO_01153	33035.JPJF01000024_gene3144	5.1e-103	301.0	COG5578@1|root,COG5578@2|Bacteria,1VI97@1239|Firmicutes,24TB6@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
NFNHFNFO_01154	33035.JPJF01000024_gene3145	0.0	1513.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3Y0MS@572511|Blautia	186801|Clostridia	G	COG COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Gal_mutarotas_2,Glyco_hydro_31
NFNHFNFO_01155	33035.JPJF01000024_gene3146	1.07e-58	182.0	COG0393@1|root,COG0393@2|Bacteria,1VADM@1239|Firmicutes,24J8R@186801|Clostridia,3Y0P1@572511|Blautia	186801|Clostridia	S	Putative heavy-metal-binding	-	-	-	-	-	-	-	-	-	-	-	-	YbjQ_1
NFNHFNFO_01156	537007.BLAHAN_06334	3.03e-60	199.0	2B3F4@1|root,31W41@2|Bacteria,1TTZ3@1239|Firmicutes,25ABE@186801|Clostridia,3Y0T7@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01157	33035.JPJF01000024_gene3148	2.13e-161	452.0	COG1131@1|root,COG1131@2|Bacteria,1TPUP@1239|Firmicutes,249FR@186801|Clostridia,3XYHK@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_01158	33035.JPJF01000024_gene3149	1.79e-75	226.0	COG1725@1|root,COG1725@2|Bacteria,1VA2B@1239|Firmicutes,24N57@186801|Clostridia,3Y05T@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GntR
NFNHFNFO_01159	33035.JPJF01000024_gene3150	8.93e-170	474.0	COG0778@1|root,COG0778@2|Bacteria,1V0I6@1239|Firmicutes,24ASS@186801|Clostridia	186801|Clostridia	C	Putative TM nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	TM1586_NiRdase
NFNHFNFO_01160	1121115.AXVN01000094_gene755	4.85e-127	384.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,2492H@186801|Clostridia,3XZGT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	abgB	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NFNHFNFO_01161	33035.JPJF01000024_gene3153	4.53e-60	198.0	COG1680@1|root,COG3439@1|root,COG1680@2|Bacteria,COG3439@2|Bacteria,1V0GX@1239|Firmicutes,24BIH@186801|Clostridia	186801|Clostridia	V	Domain of unknown function DUF302	-	-	-	-	-	-	-	-	-	-	-	-	Beta-lactamase,DUF302
NFNHFNFO_01163	33035.JPJF01000024_gene3154	1.69e-72	218.0	COG3870@1|root,COG3870@2|Bacteria,1V6NI@1239|Firmicutes,24N37@186801|Clostridia,3Y0M6@572511|Blautia	186801|Clostridia	S	Cyclic-di-AMP receptor	yaaQ	-	-	-	-	-	-	-	-	-	-	-	CdAMP_rec
NFNHFNFO_01164	33035.JPJF01000024_gene3155	8.89e-146	412.0	COG1811@1|root,COG1811@2|Bacteria,1UH19@1239|Firmicutes,24AZ3@186801|Clostridia	186801|Clostridia	S	Na channel or pump	-	-	-	ko:K07150	-	-	-	-	ko00000	-	-	-	DUF554
NFNHFNFO_01165	33035.JPJF01000024_gene3156	3.34e-79	235.0	COG0662@1|root,COG0662@2|Bacteria,1UI0P@1239|Firmicutes,24SCP@186801|Clostridia	186801|Clostridia	G	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NFNHFNFO_01166	33035.JPJF01000024_gene3157	3.16e-62	194.0	COG0437@1|root,COG0437@2|Bacteria,1V9CW@1239|Firmicutes,24KKH@186801|Clostridia,3Y073@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4
NFNHFNFO_01167	33035.JPJF01000024_gene3158	2.73e-209	579.0	COG2267@1|root,COG2267@2|Bacteria,1TRM1@1239|Firmicutes,247J5@186801|Clostridia,3XYMJ@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_4
NFNHFNFO_01168	33035.JPJF01000024_gene3159	2.52e-284	778.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248IH@186801|Clostridia,3XZFU@572511|Blautia	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	-	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
NFNHFNFO_01169	33035.JPJF01000024_gene3160	0.0	985.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3XYKD@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
NFNHFNFO_01170	33035.JPJF01000024_gene3161	7.35e-250	687.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3XZ08@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	tsgB13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NFNHFNFO_01171	33035.JPJF01000024_gene3162	7.03e-219	605.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,3XZAK@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	tsgC13	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NFNHFNFO_01172	33035.JPJF01000024_gene3163	6.79e-204	568.0	COG0340@1|root,COG1654@1|root,COG0340@2|Bacteria,COG1654@2|Bacteria,1TQCU@1239|Firmicutes,248CK@186801|Clostridia,3XYW0@572511|Blautia	186801|Clostridia	H	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor	birA	-	6.3.4.15	ko:K03524	ko00780,ko01100,map00780,map01100	-	R01074,R05145	RC00043,RC00070,RC00096,RC02896	ko00000,ko00001,ko01000,ko03000	-	-	-	BPL_C,BPL_LplA_LipB,HTH_11
NFNHFNFO_01173	33035.JPJF01000024_gene3164	3.77e-106	307.0	COG5652@1|root,COG5652@2|Bacteria,1V72A@1239|Firmicutes,259NP@186801|Clostridia,3Y02J@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NFNHFNFO_01174	33035.JPJF01000024_gene3165	1.05e-279	771.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3XYZK@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NFNHFNFO_01175	33035.JPJF01000024_gene3166	4.92e-206	569.0	COG0207@1|root,COG0207@2|Bacteria,1TSIR@1239|Firmicutes,249QG@186801|Clostridia,3XYU4@572511|Blautia	186801|Clostridia	H	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis	thyA	-	2.1.1.45	ko:K00560	ko00240,ko00670,ko01100,ko01523,map00240,map00670,map01100,map01523	M00053	R02101	RC00219,RC00332	ko00000,ko00001,ko00002,ko01000	-	-	-	Thymidylat_synt
NFNHFNFO_01176	33035.JPJF01000024_gene3167	5.62e-104	304.0	COG0262@1|root,COG0262@2|Bacteria,1VB80@1239|Firmicutes,24FTH@186801|Clostridia,3XZXR@572511|Blautia	186801|Clostridia	H	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis	folA	-	1.5.1.3	ko:K00287	ko00670,ko00790,ko01100,ko01523,map00670,map00790,map01100,map01523	M00126,M00840	R00936,R00937,R00939,R00940,R02235,R02236,R11765	RC00109,RC00110,RC00158	ko00000,ko00001,ko00002,ko01000	-	-	-	DHFR_1
NFNHFNFO_01177	33035.JPJF01000024_gene3168	3.68e-245	674.0	COG0115@1|root,COG0115@2|Bacteria,1TQQI@1239|Firmicutes,2480D@186801|Clostridia,3XZFI@572511|Blautia	186801|Clostridia	EH	Psort location Cytoplasmic, score 8.87	ilvE	-	2.6.1.42,4.1.3.38	ko:K00826,ko:K02619	ko00270,ko00280,ko00290,ko00770,ko00790,ko01100,ko01110,ko01130,ko01210,ko01230,map00270,map00280,map00290,map00770,map00790,map01100,map01110,map01130,map01210,map01230	M00019,M00036,M00119,M00570	R01090,R01214,R02199,R05553,R10991	RC00006,RC00036,RC01843,RC02148	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_4
NFNHFNFO_01178	33035.JPJF01000024_gene3169	2.89e-268	740.0	COG4915@1|root,COG4915@2|Bacteria,1U2SU@1239|Firmicutes,24B5W@186801|Clostridia,3XZ35@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Halogen_Hydrol
NFNHFNFO_01179	33035.JPJF01000024_gene3170	1.26e-250	690.0	COG3853@1|root,COG3853@2|Bacteria,1TQVX@1239|Firmicutes,24A2H@186801|Clostridia,3XYPJ@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TelA
NFNHFNFO_01180	33035.JPJF01000024_gene3171	3.43e-238	656.0	COG0821@1|root,COG0821@2|Bacteria,1TPFR@1239|Firmicutes,247N1@186801|Clostridia,3XYGT@572511|Blautia	186801|Clostridia	H	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate	ispG	-	1.17.7.1,1.17.7.3	ko:K03526	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R08689,R10859	RC01486	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06430	GcpE
NFNHFNFO_01181	33035.JPJF01000024_gene3172	0.0	2857.0	COG2176@1|root,COG2176@2|Bacteria,1TPAG@1239|Firmicutes,248YB@186801|Clostridia,3XZ9M@572511|Blautia	186801|Clostridia	L	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity	polC	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_a_NI,DNA_pol3_a_NII,DNA_pol3_alpha,HHH_6,PHP,RNase_T,tRNA_anti-codon
NFNHFNFO_01183	33035.JPJF01000024_gene3174	2.43e-283	777.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3XYMS@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
NFNHFNFO_01184	33035.JPJF01000024_gene3175	7.38e-127	361.0	COG0302@1|root,COG0302@2|Bacteria,1TRNM@1239|Firmicutes,24867@186801|Clostridia,3XZBC@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	folE	-	3.5.4.16	ko:K01495	ko00790,ko01100,map00790,map01100	M00126,M00841,M00842,M00843	R00428,R04639,R05046,R05048	RC00263,RC00294,RC00323,RC00945,RC01188	ko00000,ko00001,ko00002,ko01000	-	-	-	GTP_cyclohydroI
NFNHFNFO_01185	1123075.AUDP01000003_gene479	4.37e-61	194.0	COG1418@1|root,COG1418@2|Bacteria,1VBWP@1239|Firmicutes,24JJV@186801|Clostridia,3WJVP@541000|Ruminococcaceae	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
NFNHFNFO_01186	33035.JPJF01000024_gene3177	7.07e-182	507.0	COG0294@1|root,COG0294@2|Bacteria,1TPKT@1239|Firmicutes,248BE@186801|Clostridia,3XYIG@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives	folP	-	2.5.1.15	ko:K00796	ko00790,ko01100,map00790,map01100	M00126,M00841	R03066,R03067	RC00121,RC00842	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS03115	Pterin_bind
NFNHFNFO_01187	33035.JPJF01000024_gene3178	1e-183	512.0	COG0801@1|root,COG1539@1|root,COG0801@2|Bacteria,COG1539@2|Bacteria,1V6PR@1239|Firmicutes,249YP@186801|Clostridia,3XZG7@572511|Blautia	186801|Clostridia	H	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin	folK	-	2.7.6.3,4.1.2.25	ko:K00950,ko:K13940	ko00790,ko01100,map00790,map01100	M00126,M00841	R03503,R03504	RC00002,RC00017,RC00721,RC00943	ko00000,ko00001,ko00002,ko01000	-	-	-	FolB,HPPK
NFNHFNFO_01188	658086.HMPREF0994_01828	8.25e-165	472.0	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,248E5@186801|Clostridia,27IIT@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Pfam:UPF0118	ytvI	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NFNHFNFO_01189	658086.HMPREF0994_01827	1.36e-275	759.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,27J3I@186928|unclassified Lachnospiraceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_01190	658086.HMPREF0994_01826	6.43e-48	160.0	COG3153@1|root,COG3153@2|Bacteria,1VG0N@1239|Firmicutes,25EQF@186801|Clostridia	186801|Clostridia	S	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
NFNHFNFO_01192	33035.JPJF01000130_gene1068	0.0	866.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3XZ78@572511|Blautia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	tRNA_U5-meth_tr
NFNHFNFO_01193	33035.JPJF01000130_gene1069	6.64e-23	90.1	2E4IR@1|root,32ZDT@2|Bacteria,1VENP@1239|Firmicutes,24NT8@186801|Clostridia,3Y0CG@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01194	33035.JPJF01000130_gene1070	0.0	1417.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3XZD3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	pcrA	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
NFNHFNFO_01195	33035.JPJF01000036_gene1745	1.91e-129	369.0	COG0789@1|root,COG0789@2|Bacteria,1V1M9@1239|Firmicutes,24FUE@186801|Clostridia,3XZ5N@572511|Blautia	186801|Clostridia	K	COG NOG13858 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF1836
NFNHFNFO_01196	33035.JPJF01000036_gene1746	1.22e-145	413.0	COG1511@1|root,COG1511@2|Bacteria,1TPFN@1239|Firmicutes,24DWU@186801|Clostridia	186801|Clostridia	S	ABC-2 type transporter	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane
NFNHFNFO_01197	33035.JPJF01000036_gene1747	3.42e-152	430.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,3Y07P@572511|Blautia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990,ko:K09695	ko02010,map02010	M00252,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.102	-	-	ABC_tran
NFNHFNFO_01198	33035.JPJF01000036_gene1748	2.93e-95	279.0	COG1476@1|root,COG1476@2|Bacteria,1UUV5@1239|Firmicutes,25KCX@186801|Clostridia,3Y0TB@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_01199	33035.JPJF01000036_gene1749	7.96e-148	417.0	COG1309@1|root,COG1309@2|Bacteria,1VQ88@1239|Firmicutes	1239|Firmicutes	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_01200	33035.JPJF01000036_gene1750	1.33e-160	450.0	COG1143@1|root,COG1143@2|Bacteria	2|Bacteria	C	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient	-	-	-	ko:K11473	ko00630,ko01100,ko01110,ko01120,ko01130,map00630,map01100,map01110,map01120,map01130	-	R00475	RC00042	ko00000,ko00001	-	-	-	CCG,Fer4,Fer4_4,Fer4_8,Putative_PNPOx
NFNHFNFO_01201	33035.JPJF01000036_gene1751	1.08e-304	832.0	COG0531@1|root,COG0531@2|Bacteria,1V0MG@1239|Firmicutes,25JEH@186801|Clostridia,3Y1KU@572511|Blautia	1239|Firmicutes	E	Amino acid permease	-	-	-	-	-	-	-	-	-	-	-	-	AA_permease_2
NFNHFNFO_01202	33035.JPJF01000036_gene1752	3.55e-162	454.0	COG5015@1|root,COG5015@2|Bacteria,1TR2Q@1239|Firmicutes,24A68@186801|Clostridia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Putative_PNPOx
NFNHFNFO_01203	33035.JPJF01000036_gene1753	9.03e-127	360.0	COG1917@1|root,COG1917@2|Bacteria,1W36M@1239|Firmicutes,257HZ@186801|Clostridia	186801|Clostridia	S	Cupin 2, conserved barrel domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01204	33035.JPJF01000036_gene1754	2.56e-66	201.0	COG4496@1|root,COG4496@2|Bacteria,1VA04@1239|Firmicutes,24MX9@186801|Clostridia,3Y07E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Trp_repressor
NFNHFNFO_01205	33035.JPJF01000036_gene1755	1.61e-164	461.0	COG1387@1|root,COG1387@2|Bacteria,1TQ33@1239|Firmicutes,249TZ@186801|Clostridia,3XYKS@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K04477	-	-	-	-	ko00000	-	-	-	PHP
NFNHFNFO_01206	33035.JPJF01000036_gene1756	0.0	975.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3XYSC@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_01207	33035.JPJF01000036_gene1757	0.0	986.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3XZ0K@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fucose_iso_C
NFNHFNFO_01208	33035.JPJF01000036_gene1758	2.07e-144	407.0	28PTU@1|root,2ZCEZ@2|Bacteria,1U95M@1239|Firmicutes,247W6@186801|Clostridia,3XZXH@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4867)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4867
NFNHFNFO_01209	33035.JPJF01000036_gene1759	6.53e-110	318.0	COG0834@1|root,COG0834@2|Bacteria,1UE9Q@1239|Firmicutes,25J53@186801|Clostridia,3Y1V9@572511|Blautia	186801|Clostridia	ET	Bacterial extracellular solute-binding proteins, family 3	-	-	-	ko:K02424	ko02010,map02010	M00234	-	-	ko00000,ko00001,ko00002,ko02000,ko02035	3.A.1.3.10,3.A.1.3.14	-	-	SBP_bac_3
NFNHFNFO_01210	33035.JPJF01000008_gene1233	1.26e-215	596.0	COG1242@1|root,COG1242@2|Bacteria,1TQ57@1239|Firmicutes,247U3@186801|Clostridia,3XYHJ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ytqA	-	-	ko:K07139	-	-	-	-	ko00000	-	-	-	Radical_SAM,Radical_SAM_C
NFNHFNFO_01211	33035.JPJF01000008_gene1232	1.03e-98	288.0	COG3432@1|root,COG3432@2|Bacteria,1V75P@1239|Firmicutes,24JAZ@186801|Clostridia,3Y078@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4364
NFNHFNFO_01212	33035.JPJF01000008_gene1231	6.46e-301	822.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,3XZ05@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
NFNHFNFO_01213	33035.JPJF01000008_gene1230	6.11e-159	446.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,24H9B@186801|Clostridia,3XZX4@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	Polysacc_deac_1
NFNHFNFO_01214	33035.JPJF01000008_gene1229	3.19e-127	363.0	COG1280@1|root,COG1280@2|Bacteria,1TSNA@1239|Firmicutes,24CNE@186801|Clostridia	186801|Clostridia	E	PFAM Lysine exporter protein (LYSE YGGA)	-	-	-	ko:K11249	-	-	-	-	ko00000,ko02000	2.A.76.1.4	-	-	LysE
NFNHFNFO_01215	33035.JPJF01000008_gene1228	0.0	2038.0	COG1593@1|root,COG1638@1|root,COG1593@2|Bacteria,COG1638@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3XZAD@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctP
NFNHFNFO_01216	33035.JPJF01000008_gene1227	8.44e-107	309.0	COG3090@1|root,COG3090@2|Bacteria,1V6P9@1239|Firmicutes,24JKS@186801|Clostridia,3XZTR@572511|Blautia	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
NFNHFNFO_01217	33035.JPJF01000008_gene1225	1.39e-72	218.0	COG0292@1|root,COG0292@2|Bacteria,1V6DB@1239|Firmicutes,24JBJ@186801|Clostridia,3Y03U@572511|Blautia	186801|Clostridia	J	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit	rplT	-	-	ko:K02887	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L20
NFNHFNFO_01218	537007.BLAHAN_06860	4e-32	112.0	COG0291@1|root,COG0291@2|Bacteria,1VF5W@1239|Firmicutes,24QJD@186801|Clostridia,3Y0PB@572511|Blautia	186801|Clostridia	J	Psort location Extracellular, score 8.82	rpmI	-	-	ko:K02916	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L35p
NFNHFNFO_01219	33035.JPJF01000008_gene1224	1.48e-104	305.0	COG0290@1|root,COG0290@2|Bacteria,1V1RC@1239|Firmicutes,24FUS@186801|Clostridia,3XZXW@572511|Blautia	186801|Clostridia	J	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins	infC	-	-	ko:K02520	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	IF3_C,IF3_N
NFNHFNFO_01220	33035.JPJF01000008_gene1223	5.58e-306	836.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3XYZK@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NFNHFNFO_01221	33035.JPJF01000008_gene1222	9.89e-74	220.0	2DP3R@1|root,330E2@2|Bacteria,1VEPT@1239|Firmicutes,24QJB@186801|Clostridia,3Y0IT@572511|Blautia	186801|Clostridia	S	COG NOG16856 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF1540
NFNHFNFO_01222	33035.JPJF01000008_gene1221	0.0	1242.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3XYSJ@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
NFNHFNFO_01223	33035.JPJF01000008_gene1220	0.0	1730.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,3XZQG@572511|Blautia	186801|Clostridia	KL	Psort location Cytoplasmic, score 8.87	-	-	2.7.11.1	ko:K08282	-	-	-	-	ko00000,ko01000	-	-	-	Helicase_C,SNF2_N,SNF2_assoc,SWIM
NFNHFNFO_01224	33035.JPJF01000008_gene1219	2.98e-150	426.0	COG1434@1|root,COG1434@2|Bacteria,1VA42@1239|Firmicutes,24HKK@186801|Clostridia,3Y08M@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
NFNHFNFO_01225	33035.JPJF01000008_gene1218	5.12e-117	335.0	COG0653@1|root,COG3012@1|root,COG0653@2|Bacteria,COG3012@2|Bacteria,1V1CC@1239|Firmicutes,24FYC@186801|Clostridia,3XZU8@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	secA_2	-	-	-	-	-	-	-	-	-	-	-	SEC-C
NFNHFNFO_01226	33035.JPJF01000008_gene1217	1.52e-250	691.0	COG0673@1|root,COG0673@2|Bacteria,1V0JH@1239|Firmicutes,249FB@186801|Clostridia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NFNHFNFO_01227	33035.JPJF01000008_gene1216	1.79e-147	421.0	COG2207@1|root,COG2207@2|Bacteria,1UYFM@1239|Firmicutes,247WN@186801|Clostridia,3XZJ7@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_01228	33035.JPJF01000035_gene3485	0.0	1220.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3XYX5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NFNHFNFO_01229	658086.HMPREF0994_01111	1.97e-189	546.0	COG1874@1|root,COG1874@2|Bacteria,1UZ5Q@1239|Firmicutes,24CFY@186801|Clostridia,27REH@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 35	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_35,Glyco_hydro_42
NFNHFNFO_01230	180332.JTGN01000005_gene2973	7.71e-168	473.0	COG0395@1|root,COG0395@2|Bacteria,1TRUD@1239|Firmicutes,24CGW@186801|Clostridia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_01231	180332.JTGN01000005_gene2974	1.11e-164	464.0	COG1175@1|root,COG1175@2|Bacteria	2|Bacteria	P	transmembrane transport	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
NFNHFNFO_01232	180332.JTGN01000005_gene2975	2.36e-217	607.0	COG1653@1|root,COG1653@2|Bacteria,1V10D@1239|Firmicutes,24EK2@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
NFNHFNFO_01233	180332.JTGN01000005_gene2977	6.61e-137	398.0	COG1609@1|root,COG1609@2|Bacteria,1UYM8@1239|Firmicutes,24BYD@186801|Clostridia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_01234	180332.JTGN01000005_gene2977	3.13e-10	60.5	COG1609@1|root,COG1609@2|Bacteria,1UYM8@1239|Firmicutes,24BYD@186801|Clostridia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_01235	908340.HMPREF9406_1644	4.53e-70	221.0	2F36Y@1|root,33W1E@2|Bacteria,1VVRN@1239|Firmicutes,251F2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01236	97139.C824_03764	0.0	1094.0	COG1609@1|root,COG1879@1|root,COG1609@2|Bacteria,COG1879@2|Bacteria,1TQ7K@1239|Firmicutes,248BZ@186801|Clostridia,36E93@31979|Clostridiaceae	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3,Peripla_BP_4
NFNHFNFO_01237	97139.C824_03763	9.26e-270	739.0	COG0673@1|root,COG0673@2|Bacteria,1TSWE@1239|Firmicutes,24DSM@186801|Clostridia,36M2M@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_01238	97139.C824_03762	5.9e-196	547.0	COG1172@1|root,COG1172@2|Bacteria,1TP72@1239|Firmicutes,249FA@186801|Clostridia,36DTM@31979|Clostridiaceae	186801|Clostridia	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NFNHFNFO_01239	97139.C824_03761	2.24e-306	841.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,36DME@31979|Clostridiaceae	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	-	-	3.6.3.17	ko:K02056,ko:K17204	ko02010,map02010	M00221,M00590	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2,3.A.1.2.11,3.A.1.2.16	-	-	ABC_tran
NFNHFNFO_01240	97139.C824_03760	5.07e-214	599.0	COG1879@1|root,COG1879@2|Bacteria,1TSN1@1239|Firmicutes,249RI@186801|Clostridia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NFNHFNFO_01241	97139.C824_03759	3.64e-181	505.0	COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,24AF7@186801|Clostridia,36GBX@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
NFNHFNFO_01242	97139.C824_03758	4.25e-197	548.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,24A6G@186801|Clostridia,36G1X@31979|Clostridiaceae	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
NFNHFNFO_01243	97139.C824_03757	4.75e-265	728.0	COG0673@1|root,COG0673@2|Bacteria,1TSWE@1239|Firmicutes,24DSM@186801|Clostridia,36M2M@31979|Clostridiaceae	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_01244	33035.JPJF01000008_gene1151	1.52e-212	588.0	COG2207@1|root,COG2207@2|Bacteria,1V0IW@1239|Firmicutes,24BME@186801|Clostridia,3Y09S@572511|Blautia	2|Bacteria	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_01245	33035.JPJF01000008_gene1150	6.16e-07	51.6	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_01246	33035.JPJF01000008_gene1150	7.17e-265	727.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_01247	33035.JPJF01000008_gene1147	8.17e-38	132.0	COG2043@1|root,COG2043@2|Bacteria,1UYUH@1239|Firmicutes,24APQ@186801|Clostridia	186801|Clostridia	S	PFAM Uncharacterised ArCR, COG2043	-	-	-	-	-	-	-	-	-	-	-	-	DUF169
NFNHFNFO_01248	33035.JPJF01000008_gene1146	9.44e-146	414.0	COG3694@1|root,COG3694@2|Bacteria,1V0CD@1239|Firmicutes,248XM@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
NFNHFNFO_01249	33035.JPJF01000008_gene1145	4.34e-154	436.0	COG4587@1|root,COG4587@2|Bacteria,1UZTC@1239|Firmicutes,24E7Q@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
NFNHFNFO_01250	33035.JPJF01000008_gene1144	4.16e-201	561.0	COG4586@1|root,COG4586@2|Bacteria,1UHZR@1239|Firmicutes,25E8F@186801|Clostridia	186801|Clostridia	S	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_01251	33035.JPJF01000024_gene3219	4.5e-191	533.0	COG2207@1|root,COG2207@2|Bacteria,1UI0R@1239|Firmicutes,25E9C@186801|Clostridia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_01252	33035.JPJF01000024_gene3218	0.0	1325.0	COG3408@1|root,COG3408@2|Bacteria,1TPY5@1239|Firmicutes,249U8@186801|Clostridia,3Y0TP@572511|Blautia	186801|Clostridia	G	Alpha-L-rhamnosidase N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_C,Bac_rhamnosid_N
NFNHFNFO_01253	33035.JPJF01000024_gene3217	0.0	1004.0	COG3345@1|root,COG3345@2|Bacteria,1UB2Z@1239|Firmicutes,24B6T@186801|Clostridia	186801|Clostridia	G	Melibiase	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase
NFNHFNFO_01254	33035.JPJF01000024_gene3216	2.47e-186	519.0	COG0395@1|root,COG0395@2|Bacteria,1TR8M@1239|Firmicutes,24BHF@186801|Clostridia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_01255	33035.JPJF01000024_gene3215	1.48e-190	531.0	COG1175@1|root,COG1175@2|Bacteria,1TRA3@1239|Firmicutes,24BD8@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_01256	33035.JPJF01000024_gene3214	1.47e-302	827.0	COG1653@1|root,COG1653@2|Bacteria,1UUUZ@1239|Firmicutes,25MFR@186801|Clostridia,3Y21X@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
NFNHFNFO_01257	33035.JPJF01000024_gene3213	0.0	968.0	COG2972@1|root,COG2972@2|Bacteria,1V32G@1239|Firmicutes,25B1I@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
NFNHFNFO_01258	33035.JPJF01000024_gene3212	8.07e-303	831.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V26B@1239|Firmicutes,2480G@186801|Clostridia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
NFNHFNFO_01259	33035.JPJF01000024_gene3211	6.07e-230	635.0	COG1609@1|root,COG1609@2|Bacteria,1VT4I@1239|Firmicutes,24YJ2@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NFNHFNFO_01260	97139.C824_05669	1.14e-149	427.0	COG3550@1|root,COG3550@2|Bacteria,1V9GR@1239|Firmicutes,24DQM@186801|Clostridia,36RSF@31979|Clostridiaceae	186801|Clostridia	S	HipA-like C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	HipA_C
NFNHFNFO_01261	97139.C824_05670	1.42e-133	382.0	2DBHY@1|root,2Z9DM@2|Bacteria,1UPS2@1239|Firmicutes	1239|Firmicutes	S	HIRAN domain	-	-	-	-	-	-	-	-	-	-	-	-	Couple_hipA,HIRAN
NFNHFNFO_01262	33035.JPJF01000024_gene3210	0.0	877.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	gph	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_01263	33035.JPJF01000024_gene3209	4.07e-225	619.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,24A6G@186801|Clostridia	186801|Clostridia	G	TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
NFNHFNFO_01264	33035.JPJF01000024_gene3208	3.98e-228	627.0	COG1082@1|root,COG1082@2|Bacteria,1UZXE@1239|Firmicutes,24ECM@186801|Clostridia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NFNHFNFO_01265	33035.JPJF01000024_gene3207	1.3e-242	666.0	COG0673@1|root,COG0673@2|Bacteria,1TRHA@1239|Firmicutes,24BUV@186801|Clostridia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_01266	33035.JPJF01000024_gene3206	1.23e-86	256.0	arCOG06631@1|root,32RY6@2|Bacteria,1V8RP@1239|Firmicutes,24MV5@186801|Clostridia	186801|Clostridia	S	PFAM EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_01267	33035.JPJF01000024_gene3201	3.48e-166	469.0	COG0191@1|root,COG0191@2|Bacteria,1TRS4@1239|Firmicutes,24CD4@186801|Clostridia,3Y15G@572511|Blautia	186801|Clostridia	G	COG COG0191 Fructose tagatose bisphosphate aldolase	-	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
NFNHFNFO_01268	33035.JPJF01000024_gene3200	4.79e-252	696.0	COG0524@1|root,COG0524@2|Bacteria,1TT7Y@1239|Firmicutes,249GN@186801|Clostridia,3Y120@572511|Blautia	186801|Clostridia	G	pfkB family carbohydrate kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
NFNHFNFO_01269	33035.JPJF01000024_gene3199	2.69e-211	586.0	COG2207@1|root,COG2207@2|Bacteria,1V4S9@1239|Firmicutes,25KCU@186801|Clostridia,3Y1XZ@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_01270	658086.HMPREF0994_05990	1.14e-69	210.0	COG1917@1|root,COG1917@2|Bacteria,1VGJQ@1239|Firmicutes,25EGC@186801|Clostridia,27NAY@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NFNHFNFO_01271	33035.JPJF01000024_gene3197	6.85e-55	171.0	COG1254@1|root,COG1254@2|Bacteria,1VEM9@1239|Firmicutes,24QXB@186801|Clostridia,3Y0J7@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	acyP	-	3.6.1.7	ko:K01512	ko00620,ko00627,ko01120,map00620,map00627,map01120	-	R00317,R01421,R01515	RC00043	ko00000,ko00001,ko01000	-	-	-	Acylphosphatase
NFNHFNFO_01272	33035.JPJF01000024_gene3196	2.14e-224	619.0	COG2423@1|root,COG2423@2|Bacteria,1TPHM@1239|Firmicutes,24DP8@186801|Clostridia,3Y1YQ@572511|Blautia	186801|Clostridia	E	Ornithine cyclodeaminase/mu-crystallin family	-	-	4.3.1.12	ko:K01750	ko00330,ko01110,ko01130,ko01230,map00330,map01110,map01130,map01230	-	R00671	RC00354	ko00000,ko00001,ko01000	-	-	-	OCD_Mu_crystall
NFNHFNFO_01273	33035.JPJF01000024_gene3195	0.0	990.0	COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,2482K@186801|Clostridia	186801|Clostridia	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K05020	-	-	-	-	ko00000,ko02000	2.A.15.1.1,2.A.15.1.11	-	-	BCCT
NFNHFNFO_01274	742740.HMPREF9474_00703	3.81e-187	540.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,24A4G@186801|Clostridia	186801|Clostridia	E	Aromatic amino acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Lyase_aromatic
NFNHFNFO_01275	33035.JPJF01000024_gene3194	2e-187	524.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,24970@186801|Clostridia,3XZ9Y@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_01276	33035.JPJF01000024_gene3191	5.13e-204	566.0	COG2866@1|root,COG2866@2|Bacteria,1TP3K@1239|Firmicutes,249MT@186801|Clostridia,3Y00J@572511|Blautia	186801|Clostridia	E	Zn_pept	-	-	3.4.19.11	ko:K01308	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M14
NFNHFNFO_01277	33035.JPJF01000024_gene3190	2.78e-186	519.0	COG1011@1|root,COG1011@2|Bacteria,1V6I4@1239|Firmicutes,24JK7@186801|Clostridia,3XZZB@572511|Blautia	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	ko:K07025	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase
NFNHFNFO_01278	590998.Celf_3141	2.63e-09	65.5	COG3153@1|root,COG3153@2|Bacteria	2|Bacteria	S	transferase activity, transferring acyl groups	-	-	2.3.1.59,2.3.1.82	ko:K03824,ko:K14658,ko:K17840,ko:K18815	-	M00664	-	-	br01600,ko00000,ko00002,ko01000,ko01504	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7,Acetyltransf_9
NFNHFNFO_01279	33035.JPJF01000148_gene1657	2.22e-311	850.0	COG1066@1|root,COG1066@2|Bacteria,1TQ7Y@1239|Firmicutes,247TA@186801|Clostridia,3XYVQ@572511|Blautia	186801|Clostridia	L	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function	radA	-	-	ko:K04485	-	-	-	-	ko00000,ko03400	-	-	-	AAA_25,ATPase,ChlI,Lon_C
NFNHFNFO_01280	33035.JPJF01000148_gene1658	1.92e-88	260.0	2AU16@1|root,31JM9@2|Bacteria,1V6CJ@1239|Firmicutes,24JBF@186801|Clostridia,3Y05D@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01281	33035.JPJF01000148_gene1659	0.0	1510.0	COG0542@1|root,COG0542@2|Bacteria,1TPMU@1239|Firmicutes,247TD@186801|Clostridia,3XYKC@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 9.98	clpC	-	-	ko:K03696	ko01100,map01100	-	-	-	ko00000,ko03110	-	-	-	AAA,AAA_2,ClpB_D2-small,Clp_N
NFNHFNFO_01282	33035.JPJF01000148_gene1660	1.73e-77	231.0	COG1725@1|root,COG1725@2|Bacteria,1V743@1239|Firmicutes,24J7Q@186801|Clostridia,3Y040@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NFNHFNFO_01283	33035.JPJF01000148_gene1661	1.46e-301	823.0	COG0151@1|root,COG0151@2|Bacteria,1UHN9@1239|Firmicutes,25E76@186801|Clostridia,3XYZ3@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purD	-	6.3.4.13	ko:K01945	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04144	RC00090,RC00166	ko00000,ko00001,ko00002,ko01000	-	-	-	GARS_A,GARS_C,GARS_N
NFNHFNFO_01284	33035.JPJF01000148_gene1662	2.3e-135	384.0	COG0299@1|root,COG0299@2|Bacteria,1V3RJ@1239|Firmicutes,249JC@186801|Clostridia,3XYPA@572511|Blautia	186801|Clostridia	F	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate	purN	-	2.1.2.2	ko:K11175	ko00230,ko00670,ko01100,ko01110,ko01130,map00230,map00670,map01100,map01110,map01130	M00048	R04325,R04326	RC00026,RC00197,RC01128	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04225	Formyl_trans_N
NFNHFNFO_01285	33035.JPJF01000148_gene1663	1.36e-244	672.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,3XYWD@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purM	-	6.3.3.1	ko:K01933	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04208	RC01100	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C
NFNHFNFO_01286	33035.JPJF01000021_gene3393	9.2e-110	316.0	COG0041@1|root,COG0041@2|Bacteria,1V1MV@1239|Firmicutes,24HCB@186801|Clostridia,3XZ51@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)	purE	-	5.4.99.18	ko:K01588	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R07405	RC01947	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRC
NFNHFNFO_01287	33035.JPJF01000021_gene3391	0.0	1216.0	COG2309@1|root,COG2309@2|Bacteria,1TSPE@1239|Firmicutes,24A6S@186801|Clostridia,3XYTQ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M29
NFNHFNFO_01288	33035.JPJF01000021_gene3390	5.01e-117	337.0	COG1896@1|root,COG1896@2|Bacteria,1V3MK@1239|Firmicutes,24IBW@186801|Clostridia,3XZ0F@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
NFNHFNFO_01289	33035.JPJF01000021_gene3389	2.17e-59	184.0	2EENY@1|root,338GS@2|Bacteria,1VJM1@1239|Firmicutes,24T09@186801|Clostridia,3Y0JX@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01290	33035.JPJF01000021_gene3388	1.87e-107	310.0	COG4767@1|root,COG4767@2|Bacteria,1VAH6@1239|Firmicutes,24MQR@186801|Clostridia,3Y09R@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NFNHFNFO_01291	33035.JPJF01000021_gene3387	9.49e-09	52.4	2DRBT@1|root,33B4Z@2|Bacteria,1VMZQ@1239|Firmicutes,24UIT@186801|Clostridia,3Y0RQ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01292	33035.JPJF01000021_gene3386	7.4e-154	432.0	COG0461@1|root,COG0461@2|Bacteria,1TREW@1239|Firmicutes,248WM@186801|Clostridia,3XYW9@572511|Blautia	186801|Clostridia	F	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)	pyrE	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran
NFNHFNFO_01293	33035.JPJF01000021_gene3385	1.29e-205	570.0	COG0167@1|root,COG0167@2|Bacteria,1TPFV@1239|Firmicutes,248CQ@186801|Clostridia,3XZ9C@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of dihydroorotate to orotate	pyrD	-	1.3.1.14	ko:K17828	ko00240,ko01100,map00240,map01100	M00051	R01869	RC00051	ko00000,ko00001,ko00002,ko01000	-	-	-	DHO_dh
NFNHFNFO_01294	33035.JPJF01000021_gene3384	2.94e-165	464.0	COG0543@1|root,COG0543@2|Bacteria,1TQ5D@1239|Firmicutes,24AY2@186801|Clostridia,3XZA9@572511|Blautia	186801|Clostridia	C	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( )	pyrK	-	-	ko:K02823	ko00240,ko01100,map00240,map01100	-	-	-	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
NFNHFNFO_01295	33035.JPJF01000021_gene3383	1e-218	603.0	COG0284@1|root,COG0284@2|Bacteria,1TQ7P@1239|Firmicutes,247SZ@186801|Clostridia,3XZ6C@572511|Blautia	186801|Clostridia	F	Belongs to the OMP decarboxylase family. Type 2 subfamily	pyrF	-	4.1.1.23	ko:K01591	ko00240,ko01100,map00240,map01100	M00051	R00965	RC00409	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17585	OMPdecase
NFNHFNFO_01296	33035.JPJF01000021_gene3382	2.67e-308	840.0	COG0044@1|root,COG0044@2|Bacteria,1TPQM@1239|Firmicutes,247V2@186801|Clostridia,3XYP9@572511|Blautia	186801|Clostridia	F	Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily	pyrC	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1
NFNHFNFO_01297	33035.JPJF01000021_gene3381	1.04e-41	136.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia,3Y0CS@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
NFNHFNFO_01298	33035.JPJF01000021_gene3380	1.69e-276	771.0	COG2199@1|root,COG2199@2|Bacteria,1VTNV@1239|Firmicutes,24Y0C@186801|Clostridia,3Y1SI@572511|Blautia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NFNHFNFO_01299	33035.JPJF01000021_gene3379	9.59e-47	150.0	2DRX4@1|root,33DGR@2|Bacteria,1VKQ3@1239|Firmicutes,24URP@186801|Clostridia,3Y0RT@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01300	33035.JPJF01000021_gene3378	9.45e-39	129.0	2BCQI@1|root,326AY@2|Bacteria,1US91@1239|Firmicutes,25A84@186801|Clostridia,3Y22C@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01301	33035.JPJF01000021_gene3377	2.25e-197	550.0	COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes,24AQF@186801|Clostridia,3XZ37@572511|Blautia	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NFNHFNFO_01302	33035.JPJF01000021_gene3376	1.93e-117	336.0	COG1853@1|root,COG1853@2|Bacteria,1V41U@1239|Firmicutes,24HTA@186801|Clostridia,3Y0NR@572511|Blautia	186801|Clostridia	S	Flavin reductase like domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NFNHFNFO_01303	33035.JPJF01000021_gene3375	0.0	1033.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3XYYI@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	malQ	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
NFNHFNFO_01304	33035.JPJF01000021_gene3374	6.06e-173	483.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248W2@186801|Clostridia,3XYU9@572511|Blautia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
NFNHFNFO_01305	33035.JPJF01000021_gene3373	1.3e-172	483.0	COG0619@1|root,COG0619@2|Bacteria,1TQ0E@1239|Firmicutes,248AB@186801|Clostridia,3XYPD@572511|Blautia	186801|Clostridia	P	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfT	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
NFNHFNFO_01306	33035.JPJF01000021_gene3372	2.81e-197	547.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3XZ7W@572511|Blautia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NFNHFNFO_01307	33035.JPJF01000021_gene3371	1.45e-197	548.0	COG1122@1|root,COG1122@2|Bacteria,1TPH8@1239|Firmicutes,248A2@186801|Clostridia,3XZE9@572511|Blautia	186801|Clostridia	P	ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates	ecfA2	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran
NFNHFNFO_01308	33035.JPJF01000021_gene3370	2.75e-268	736.0	COG0637@1|root,COG0637@2|Bacteria,1V1NW@1239|Firmicutes,24G37@186801|Clostridia,3Y0ZE@572511|Blautia	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,HAD_2
NFNHFNFO_01309	33035.JPJF01000021_gene3369	1.72e-136	386.0	COG0218@1|root,COG0218@2|Bacteria,1TSPW@1239|Firmicutes,24836@186801|Clostridia,3XZB9@572511|Blautia	186801|Clostridia	D	Necessary for normal cell division and for the maintenance of normal septation	engB	-	-	ko:K03978	-	-	-	-	ko00000,ko03036	-	-	-	MMR_HSR1
NFNHFNFO_01310	33035.JPJF01000021_gene3368	0.0	1399.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3XYJU@572511|Blautia	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
NFNHFNFO_01311	33035.JPJF01000021_gene3367	1.37e-305	833.0	COG1219@1|root,COG1219@2|Bacteria,1TQ00@1239|Firmicutes,2481T@186801|Clostridia,3XYHZ@572511|Blautia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
NFNHFNFO_01312	33035.JPJF01000021_gene3366	1.72e-134	381.0	COG0740@1|root,COG0740@2|Bacteria,1TQ91@1239|Firmicutes,247QY@186801|Clostridia,3XYT9@572511|Blautia	186801|Clostridia	OU	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins	clpP	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NFNHFNFO_01313	33035.JPJF01000021_gene3365	2.4e-281	773.0	COG0544@1|root,COG0544@2|Bacteria,1TQQ8@1239|Firmicutes,248C3@186801|Clostridia,3XYJC@572511|Blautia	186801|Clostridia	D	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase	tig	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C,Trigger_N
NFNHFNFO_01314	33035.JPJF01000021_gene3364	3.77e-114	328.0	COG0693@1|root,COG0693@2|Bacteria,1V3WB@1239|Firmicutes,24HGU@186801|Clostridia,3Y01K@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yajL	-	3.5.1.124	ko:K03152	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	DJ-1_PfpI
NFNHFNFO_01315	33035.JPJF01000021_gene3363	2.07e-97	284.0	COG2954@1|root,COG2954@2|Bacteria,1V7MS@1239|Firmicutes,24JER@186801|Clostridia,3Y0AV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	CYTH
NFNHFNFO_01317	33035.JPJF01000021_gene3361	2.11e-161	455.0	COG0345@1|root,COG0345@2|Bacteria,1TP1E@1239|Firmicutes,247SR@186801|Clostridia,3XZDC@572511|Blautia	186801|Clostridia	E	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline	proC	-	1.5.1.2	ko:K00286	ko00330,ko01100,ko01110,ko01130,ko01230,map00330,map01100,map01110,map01130,map01230	M00015	R01248,R01251,R03291,R03293	RC00054,RC00083	ko00000,ko00001,ko00002,ko01000	-	-	-	F420_oxidored,P5CR_dimer
NFNHFNFO_01318	33035.JPJF01000021_gene3360	2.47e-84	251.0	2E66T@1|root,330VC@2|Bacteria,1VHCY@1239|Firmicutes,24MYI@186801|Clostridia,3Y0NW@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01319	33035.JPJF01000021_gene3359	1.11e-54	171.0	2BD58@1|root,326SW@2|Bacteria,1USNX@1239|Firmicutes,25MVJ@186801|Clostridia,3Y1YZ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01321	33035.JPJF01000021_gene3357	5.78e-60	186.0	COG1476@1|root,COG1476@2|Bacteria,1V789@1239|Firmicutes,24IXV@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NFNHFNFO_01322	33035.JPJF01000021_gene3356	2.27e-188	526.0	COG2207@1|root,COG2207@2|Bacteria,1TQ2W@1239|Firmicutes,24A5W@186801|Clostridia,3XZZM@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NFNHFNFO_01323	33035.JPJF01000021_gene3355	2.51e-223	617.0	COG0715@1|root,COG0715@2|Bacteria,1TQN5@1239|Firmicutes,248IG@186801|Clostridia,3XYQP@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02051	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	NMT1,NMT1_2
NFNHFNFO_01325	33035.JPJF01000021_gene3354	0.0	1454.0	COG5426@1|root,COG5426@2|Bacteria,1TPH0@1239|Firmicutes,24892@186801|Clostridia,3XZ5G@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	gnpA	GO:0003674,GO:0003824,GO:0004645,GO:0005975,GO:0008150,GO:0008152,GO:0016740,GO:0016757,GO:0016758,GO:0044238,GO:0050500,GO:0071704	2.4.1.211	ko:K15533	-	-	-	-	ko00000,ko01000	-	-	-	LBP_C,LBP_M,Lact_bio_phlase
NFNHFNFO_01326	33035.JPJF01000021_gene3353	0.0	967.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,3XYNQ@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 9.99	mleN_1	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
NFNHFNFO_01328	33035.JPJF01000021_gene3352	5.71e-136	385.0	COG1102@1|root,COG1102@2|Bacteria,1V79E@1239|Firmicutes,24GMW@186801|Clostridia,3XZZJ@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NFNHFNFO_01329	33035.JPJF01000021_gene3351	1.03e-46	150.0	2EAZP@1|root,3350I@2|Bacteria,1VHB0@1239|Firmicutes,24RTB@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01330	33035.JPJF01000021_gene3350	1.2e-65	202.0	2EA9N@1|root,305PD@2|Bacteria,1V547@1239|Firmicutes,24IYT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01331	33035.JPJF01000021_gene3349	1.39e-72	218.0	COG3877@1|root,COG3877@2|Bacteria,1VAFG@1239|Firmicutes,24MSP@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2089
NFNHFNFO_01332	33035.JPJF01000021_gene3348	5.19e-235	649.0	COG0330@1|root,COG0330@2|Bacteria,1TR6S@1239|Firmicutes,24A7V@186801|Clostridia	186801|Clostridia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
NFNHFNFO_01333	33035.JPJF01000021_gene3347	1.32e-249	691.0	COG2378@1|root,COG2378@2|Bacteria,1TQYS@1239|Firmicutes,24B1B@186801|Clostridia	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	WYL
NFNHFNFO_01334	33035.JPJF01000021_gene3346	4.21e-189	531.0	2DBKZ@1|root,2Z9WA@2|Bacteria,1TRUJ@1239|Firmicutes,24ATT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	WYL
NFNHFNFO_01335	33035.JPJF01000021_gene3345	3.96e-196	545.0	COG2207@1|root,COG2207@2|Bacteria,1TQDS@1239|Firmicutes,24907@186801|Clostridia	186801|Clostridia	K	AraC family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NFNHFNFO_01336	33035.JPJF01000021_gene3344	1.13e-97	284.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3Y0EE@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NFNHFNFO_01337	33035.JPJF01000021_gene3343	8.13e-300	819.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XYTJ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NFNHFNFO_01338	33035.JPJF01000021_gene3342	3.78e-202	562.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3XZJH@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NFNHFNFO_01339	33035.JPJF01000021_gene3341	1.57e-269	758.0	arCOG08054@1|root,2Z8AD@2|Bacteria,1TQ1J@1239|Firmicutes,2485U@186801|Clostridia,3XZHV@572511|Blautia	186801|Clostridia	S	Carbohydrate-binding domain-containing protein Cthe_2159	-	GO:0001871,GO:0003674,GO:0005488,GO:0005509,GO:0030246,GO:0030247,GO:0030248,GO:0043167,GO:0043169,GO:0046872,GO:0048028,GO:2001062	-	-	-	-	-	-	-	-	-	-	Cthe_2159
NFNHFNFO_01340	33035.JPJF01000021_gene3340	1.34e-126	364.0	COG1285@1|root,COG1285@2|Bacteria,1V1GI@1239|Firmicutes,24G1I@186801|Clostridia,3XZXM@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4956)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
NFNHFNFO_01341	33035.JPJF01000021_gene3339	3.8e-142	405.0	COG5036@1|root,COG5036@2|Bacteria,1V1FZ@1239|Firmicutes,24FRH@186801|Clostridia,3Y09M@572511|Blautia	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
NFNHFNFO_01342	33035.JPJF01000021_gene3338	1.77e-249	696.0	COG0642@1|root,COG2205@2|Bacteria,1UHUJ@1239|Firmicutes,25E2Z@186801|Clostridia,3XZRC@572511|Blautia	186801|Clostridia	T	GHKL domain	dltS	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_01343	33035.JPJF01000021_gene3337	2.46e-147	416.0	COG0745@1|root,COG0745@2|Bacteria,1TPU2@1239|Firmicutes,24B71@186801|Clostridia,3XZYT@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	dltR	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_01345	33035.JPJF01000021_gene3335	1.1e-220	612.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia,3XZ2C@572511|Blautia	186801|Clostridia	M	Bacterial capsule synthesis protein PGA_cap	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap,Peptidase_M15
NFNHFNFO_01346	33035.JPJF01000045_gene1019	1.3e-29	109.0	COG1396@1|root,COG1396@2|Bacteria,1V62P@1239|Firmicutes,24R9W@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_01347	33035.JPJF01000021_gene3328	1.63e-280	769.0	COG2233@1|root,COG2233@2|Bacteria,1TQKX@1239|Firmicutes,2485Z@186801|Clostridia,3XYT0@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	pyrP	-	-	ko:K02824	-	-	-	-	ko00000,ko02000	2.A.40.1.1,2.A.40.1.2	-	-	Xan_ur_permease
NFNHFNFO_01348	33035.JPJF01000021_gene3327	0.0	940.0	COG1904@1|root,COG1904@2|Bacteria,1TRI0@1239|Firmicutes,248C0@186801|Clostridia,3XYR6@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	uxaC	-	5.3.1.12	ko:K01812	ko00040,ko01100,map00040,map01100	M00061,M00631	R01482,R01983	RC00376	ko00000,ko00001,ko00002,ko01000	-	-	-	UxaC
NFNHFNFO_01349	411461.DORFOR_00430	1.16e-253	702.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DctM
NFNHFNFO_01350	33035.JPJF01000074_gene5003	5.37e-88	260.0	COG3090@1|root,COG3090@2|Bacteria,1TUNS@1239|Firmicutes,25N0G@186801|Clostridia,3Y0U4@572511|Blautia	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
NFNHFNFO_01351	33035.JPJF01000074_gene5004	4.29e-231	637.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,24BWQ@186801|Clostridia,3Y2BW@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
NFNHFNFO_01352	33035.JPJF01000074_gene5005	2.05e-230	635.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3Y15K@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	ccpA	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NFNHFNFO_01353	33035.JPJF01000074_gene5006	0.0	912.0	COG2721@1|root,COG2721@2|Bacteria,1TPTX@1239|Firmicutes,24AEC@186801|Clostridia,3XZTB@572511|Blautia	186801|Clostridia	G	SAF	uxaA	-	4.2.1.7	ko:K01685	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C,SAF
NFNHFNFO_01354	33035.JPJF01000074_gene5007	0.0	952.0	COG0246@1|root,COG0246@2|Bacteria,1TPZU@1239|Firmicutes,248J5@186801|Clostridia,3XZK5@572511|Blautia	186801|Clostridia	G	Mannitol dehydrogenase C-terminal domain	-	-	1.1.1.58	ko:K00041	ko00040,ko01100,map00040,map01100	M00631	R02555	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
NFNHFNFO_01355	33035.JPJF01000074_gene5008	4.91e-181	507.0	COG2227@1|root,COG2227@2|Bacteria,1UXZZ@1239|Firmicutes,24BIT@186801|Clostridia	186801|Clostridia	H	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_25
NFNHFNFO_01356	33035.JPJF01000074_gene5009	3.26e-113	324.0	COG4894@1|root,COG4894@2|Bacteria,1V3WA@1239|Firmicutes,24MB0@186801|Clostridia,3Y1VJ@572511|Blautia	186801|Clostridia	S	LURP-one-related	-	-	-	-	-	-	-	-	-	-	-	-	LOR
NFNHFNFO_01357	33035.JPJF01000074_gene5010	5.07e-213	590.0	COG0332@1|root,COG0332@2|Bacteria,1TP0K@1239|Firmicutes,248V8@186801|Clostridia,3XYXI@572511|Blautia	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids	fabH	-	2.3.1.180	ko:K00648	ko00061,ko01100,ko01212,map00061,map01100,map01212	M00082,M00083	R10707	RC00004,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	ACP_syn_III,ACP_syn_III_C
NFNHFNFO_01358	33035.JPJF01000074_gene5011	1.32e-171	486.0	2E6QY@1|root,331B3@2|Bacteria,1UI1C@1239|Firmicutes,24Z9X@186801|Clostridia,3Y0GV@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4203
NFNHFNFO_01359	33035.JPJF01000074_gene5012	4.23e-129	366.0	2943S@1|root,2ZRIE@2|Bacteria,1V3J6@1239|Firmicutes,24HEP@186801|Clostridia,3XZW0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	KatE	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01360	33035.JPJF01000074_gene5013	0.0	1156.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,3XZJM@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
NFNHFNFO_01361	33035.JPJF01000074_gene5014	0.0	944.0	COG0038@1|root,COG0569@1|root,COG0038@2|Bacteria,COG0569@2|Bacteria,1TPX0@1239|Firmicutes,247R4@186801|Clostridia,3XZHT@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	clcA	-	-	-	-	-	-	-	-	-	-	-	TrkA_C,Voltage_CLC
NFNHFNFO_01362	33035.JPJF01000074_gene5015	1.05e-87	258.0	2E3QR@1|root,32YNK@2|Bacteria,1VENX@1239|Firmicutes,24QVR@186801|Clostridia,3Y0KX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1292
NFNHFNFO_01363	33035.JPJF01000074_gene5016	3.37e-220	606.0	COG2159@1|root,COG2159@2|Bacteria	2|Bacteria	E	amidohydrolase	-	-	-	ko:K07045	-	-	-	-	ko00000	-	-	-	Amidohydro_2
NFNHFNFO_01364	33035.JPJF01000074_gene5017	5.92e-166	469.0	COG5464@1|root,COG5464@2|Bacteria,1V2ZE@1239|Firmicutes	1239|Firmicutes	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351
NFNHFNFO_01365	33035.JPJF01000074_gene5018	4.06e-267	733.0	COG3007@1|root,COG3007@2|Bacteria,1TWIF@1239|Firmicutes,249TW@186801|Clostridia,3XZSQ@572511|Blautia	186801|Clostridia	I	Involved in the fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon-carbon double bond in an enoyl moiety that is covalently linked to a coenzyme A (CoA)	fabV	GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050343,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576	1.3.1.44,1.3.1.9	ko:K00209	ko00061,ko00650,ko01100,ko01120,ko01200,ko01212,map00061,map00650,map01100,map01120,map01200,map01212	M00083	R01171,R04429,R04724,R04955,R04958,R04961,R04966,R04969	RC00052,RC00076	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Eno-Rase_FAD_bd,Eno-Rase_NADH_b,Enoyl_reductase
NFNHFNFO_01366	33035.JPJF01000074_gene5019	7.28e-113	327.0	COG1309@1|root,COG1309@2|Bacteria,1UUVH@1239|Firmicutes,25MJR@186801|Clostridia,3Y1JB@572511|Blautia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_01367	33035.JPJF01000074_gene5020	1.43e-154	437.0	COG2820@1|root,COG2820@2|Bacteria,1TQ71@1239|Firmicutes,2482S@186801|Clostridia,3XYV1@572511|Blautia	186801|Clostridia	F	Phosphorylase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PNP_UDP_1
NFNHFNFO_01368	33035.JPJF01000074_gene5022	2.5e-114	328.0	COG0756@1|root,COG0756@2|Bacteria,1V6HX@1239|Firmicutes,24GHG@186801|Clostridia,3XZTE@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	dut	-	3.6.1.23	ko:K01520	ko00240,ko00983,ko01100,map00240,map00983,map01100	M00053	R02100,R11896	RC00002	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	dUTPase
NFNHFNFO_01369	33035.JPJF01000074_gene5023	2.98e-111	320.0	COG0602@1|root,COG0602@2|Bacteria,1V1HG@1239|Firmicutes,24HIJ@186801|Clostridia,3XZW3@572511|Blautia	186801|Clostridia	C	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	nrdG	-	1.97.1.4	ko:K04068	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NFNHFNFO_01370	33035.JPJF01000074_gene5024	0.0	1346.0	COG1185@1|root,COG1185@2|Bacteria,1TQDW@1239|Firmicutes,248RW@186801|Clostridia,3XZKB@572511|Blautia	186801|Clostridia	J	Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction	pnp	-	2.7.7.8	ko:K00962	ko00230,ko00240,ko03018,map00230,map00240,map03018	M00394	R00437,R00438,R00439,R00440	RC02795	ko00000,ko00001,ko00002,ko01000,ko03016,ko03019	-	-	-	KH_1,PNPase,RNase_PH,RNase_PH_C,S1
NFNHFNFO_01371	33035.JPJF01000074_gene5025	3.03e-54	170.0	COG0184@1|root,COG0184@2|Bacteria,1VA5C@1239|Firmicutes,24MRM@186801|Clostridia,3Y0EQ@572511|Blautia	186801|Clostridia	J	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome	rpsO	-	-	ko:K02956	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S15
NFNHFNFO_01372	33035.JPJF01000074_gene5026	1.27e-171	479.0	COG0791@1|root,COG0791@2|Bacteria,1UBS0@1239|Firmicutes,25B2D@186801|Clostridia,3Y0CZ@572511|Blautia	186801|Clostridia	M	NlpC/P60 family	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,SH3_3
NFNHFNFO_01373	33035.JPJF01000074_gene5027	0.0	1002.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3XYUW@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
NFNHFNFO_01374	33035.JPJF01000074_gene5028	1.87e-218	603.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,3XZMT@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
NFNHFNFO_01375	33035.JPJF01000074_gene5029	3.11e-198	551.0	COG0130@1|root,COG0130@2|Bacteria,1TP9Y@1239|Firmicutes,24B46@186801|Clostridia,3XYQ5@572511|Blautia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs	truB	-	5.4.99.25	ko:K03177	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	TruB-C_2,TruB_C_2,TruB_N
NFNHFNFO_01376	33035.JPJF01000074_gene5030	1.03e-217	602.0	COG0618@1|root,COG0618@2|Bacteria,1TPXX@1239|Firmicutes,248R3@186801|Clostridia,3XZ2Y@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	nrnA	-	3.1.13.3,3.1.3.7	ko:K06881	ko00920,ko01100,ko01120,map00920,map01100,map01120	-	R00188,R00508	RC00078	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
NFNHFNFO_01377	33035.JPJF01000074_gene5031	1.54e-82	244.0	COG0858@1|root,COG0858@2|Bacteria,1VA0P@1239|Firmicutes,24MPB@186801|Clostridia,3Y0A9@572511|Blautia	186801|Clostridia	J	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA	rbfA	-	-	ko:K02834	-	-	-	-	ko00000,ko03009	-	-	-	RBFA
NFNHFNFO_01378	33035.JPJF01000074_gene5032	0.0	1187.0	COG0532@1|root,COG0532@2|Bacteria,1TPAI@1239|Firmicutes,248SJ@186801|Clostridia,3XZRI@572511|Blautia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex	infB	-	-	ko:K02519	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	GTP_EFTU,IF-2,IF2_N
NFNHFNFO_01379	33035.JPJF01000101_gene3244	4.86e-45	145.0	COG0361@1|root,COG0361@2|Bacteria,1V9ZK@1239|Firmicutes,24MQE@186801|Clostridia,3Y0HJ@572511|Blautia	186801|Clostridia	J	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex	infA	-	-	ko:K02518	-	-	-	-	ko00000,ko03012	-	-	-	eIF-1a
NFNHFNFO_01380	33035.JPJF01000101_gene3245	6.27e-52	164.0	COG2163@1|root,COG2163@2|Bacteria,1UG5G@1239|Firmicutes,25NCZ@186801|Clostridia,3Y0WA@572511|Blautia	186801|Clostridia	J	COG2163 Ribosomal protein L14E L6E L27E	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01381	33035.JPJF01000101_gene3246	1.22e-171	479.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3XZ5M@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24
NFNHFNFO_01382	33035.JPJF01000101_gene3247	2.15e-152	428.0	COG0563@1|root,COG0563@2|Bacteria,1TP27@1239|Firmicutes,247YN@186801|Clostridia,3XZAB@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism	adk	-	2.7.4.3	ko:K00939	ko00230,ko00730,ko01100,ko01110,ko01130,map00230,map00730,map01100,map01110,map01130	M00049	R00127,R01547,R11319	RC00002	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS20110	ADK,ADK_lid
NFNHFNFO_01383	33035.JPJF01000101_gene3248	1.99e-273	752.0	COG0201@1|root,COG0201@2|Bacteria,1TPHB@1239|Firmicutes,248T9@186801|Clostridia,3XYT7@572511|Blautia	186801|Clostridia	U	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently	secY	-	-	ko:K03076	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5	-	-	SecY
NFNHFNFO_01384	33035.JPJF01000101_gene3249	1.21e-93	274.0	COG0200@1|root,COG0200@2|Bacteria,1V3KE@1239|Firmicutes,24HAJ@186801|Clostridia,3XZUB@572511|Blautia	186801|Clostridia	J	Binds to the 23S rRNA	rplO	-	-	ko:K02876	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L27A
NFNHFNFO_01385	33035.JPJF01000101_gene3250	2e-32	112.0	COG1841@1|root,COG1841@2|Bacteria,1VEG4@1239|Firmicutes,24QKC@186801|Clostridia,3Y0NM@572511|Blautia	186801|Clostridia	J	Ribosomal protein L30p/L7e	rpmD	-	-	ko:K02907	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L30
NFNHFNFO_01386	33035.JPJF01000101_gene3251	1.2e-111	321.0	COG0098@1|root,COG0098@2|Bacteria,1V1B1@1239|Firmicutes,24G5D@186801|Clostridia,3XZM0@572511|Blautia	186801|Clostridia	J	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body	rpsE	-	-	ko:K02988	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S5,Ribosomal_S5_C
NFNHFNFO_01387	537007.BLAHAN_06364	1.12e-73	221.0	COG0256@1|root,COG0256@2|Bacteria,1V6DM@1239|Firmicutes,24JCS@186801|Clostridia,3XZZX@572511|Blautia	186801|Clostridia	J	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance	rplR	-	-	ko:K02881	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L18p
NFNHFNFO_01388	33035.JPJF01000101_gene3253	6.34e-121	345.0	COG0097@1|root,COG0097@2|Bacteria,1V1FC@1239|Firmicutes,2496R@186801|Clostridia,3XYVK@572511|Blautia	186801|Clostridia	J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center	rplF	-	-	ko:K02933	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L6
NFNHFNFO_01389	33035.JPJF01000101_gene3254	1.42e-88	260.0	COG0096@1|root,COG0096@2|Bacteria,1V3KK@1239|Firmicutes,24HCP@186801|Clostridia,3Y02G@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit	rpsH	-	-	ko:K02994	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S8
NFNHFNFO_01390	411468.CLOSCI_02212	2.73e-26	97.4	COG0199@1|root,COG0199@2|Bacteria,1VEF6@1239|Firmicutes,24QR1@186801|Clostridia,220VY@1506553|Lachnoclostridium	186801|Clostridia	J	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site	rpsN	-	-	ko:K02954	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S14
NFNHFNFO_01391	33035.JPJF01000101_gene3255	5.43e-122	348.0	COG0094@1|root,COG0094@2|Bacteria,1TPE0@1239|Firmicutes,247X0@186801|Clostridia,3XZR3@572511|Blautia	186801|Clostridia	J	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits	rplE	-	-	ko:K02931	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L5,Ribosomal_L5_C
NFNHFNFO_01392	33035.JPJF01000101_gene3256	1.67e-66	202.0	COG0198@1|root,COG0198@2|Bacteria,1V9ZQ@1239|Firmicutes,24MY0@186801|Clostridia,3Y0BX@572511|Blautia	186801|Clostridia	J	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit	rplX	-	-	ko:K02895	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KOW,ribosomal_L24
NFNHFNFO_01393	1256908.HMPREF0373_01063	1.48e-78	234.0	COG0093@1|root,COG0093@2|Bacteria,1V3N0@1239|Firmicutes,24H98@186801|Clostridia,25WCX@186806|Eubacteriaceae	186801|Clostridia	J	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome	rplN	-	-	ko:K02874	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L14
NFNHFNFO_01394	457412.RSAG_02853	3.52e-48	154.0	COG0186@1|root,COG0186@2|Bacteria,1V9YC@1239|Firmicutes,24MSW@186801|Clostridia,3WJV0@541000|Ruminococcaceae	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA	rpsQ	-	-	ko:K02961	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S17
NFNHFNFO_01395	33035.JPJF01000101_gene3259	3.01e-36	123.0	COG0255@1|root,COG0255@2|Bacteria,1VEME@1239|Firmicutes,24QV1@186801|Clostridia,3Y0MW@572511|Blautia	186801|Clostridia	J	Belongs to the universal ribosomal protein uL29 family	rpmC	-	-	ko:K02904	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L29
NFNHFNFO_01396	537007.BLAHAN_06374	5.38e-101	292.0	COG0197@1|root,COG0197@2|Bacteria,1V1AY@1239|Firmicutes,24FQX@186801|Clostridia,3XYIJ@572511|Blautia	186801|Clostridia	J	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs	rplP	-	-	ko:K02878	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L16
NFNHFNFO_01397	33035.JPJF01000101_gene3261	1.19e-151	426.0	COG0092@1|root,COG0092@2|Bacteria,1TPCP@1239|Firmicutes,24833@186801|Clostridia,3XZ7Y@572511|Blautia	186801|Clostridia	J	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation	rpsC	-	-	ko:K02982	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	KH_2,Ribosomal_S3_C
NFNHFNFO_01398	537007.BLAHAN_06376	1.06e-83	247.0	COG0091@1|root,COG0091@2|Bacteria,1V6PU@1239|Firmicutes,24JF4@186801|Clostridia,3XZZ2@572511|Blautia	186801|Clostridia	J	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome	rplV	-	-	ko:K02890	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L22
NFNHFNFO_01399	33035.JPJF01000101_gene3263	3.05e-62	190.0	COG0185@1|root,COG0185@2|Bacteria,1V6CX@1239|Firmicutes,24JN3@186801|Clostridia,3Y09D@572511|Blautia	186801|Clostridia	J	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA	rpsS	-	-	ko:K02965	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S19
NFNHFNFO_01400	33035.JPJF01000101_gene3264	1.17e-199	553.0	COG0090@1|root,COG0090@2|Bacteria,1TP9X@1239|Firmicutes,247XY@186801|Clostridia,3XZ12@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity	rplB	-	-	ko:K02886	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L2,Ribosomal_L2_C
NFNHFNFO_01401	33035.JPJF01000101_gene3265	2.73e-61	188.0	COG0089@1|root,COG0089@2|Bacteria,1VA4W@1239|Firmicutes,24MN8@186801|Clostridia,3Y06M@572511|Blautia	186801|Clostridia	J	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome	rplW	-	-	ko:K02892	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L23
NFNHFNFO_01402	33035.JPJF01000101_gene3266	1.14e-134	382.0	COG0088@1|root,COG0088@2|Bacteria,1TPGW@1239|Firmicutes,248SY@186801|Clostridia,3XZH3@572511|Blautia	186801|Clostridia	J	Forms part of the polypeptide exit tunnel	rplD	-	-	ko:K02926	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L4
NFNHFNFO_01403	33035.JPJF01000101_gene3267	8.39e-144	406.0	COG0087@1|root,COG0087@2|Bacteria,1TPFT@1239|Firmicutes,247NH@186801|Clostridia,3XZ95@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit	rplC	-	-	ko:K02906	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L3
NFNHFNFO_01404	33035.JPJF01000101_gene3268	1.94e-66	202.0	COG0051@1|root,COG0051@2|Bacteria,1V6C9@1239|Firmicutes,24JDC@186801|Clostridia,3XZZ4@572511|Blautia	186801|Clostridia	J	Involved in the binding of tRNA to the ribosomes	rpsJ	-	-	ko:K02946	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S10
NFNHFNFO_01405	33035.JPJF01000057_gene3105	1.47e-238	660.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3XYME@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
NFNHFNFO_01406	33035.JPJF01000101_gene3269	8.14e-214	592.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,3XZ3D@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
NFNHFNFO_01408	33035.JPJF01000101_gene3271	1.03e-156	453.0	COG0681@1|root,COG0681@2|Bacteria,1VVMI@1239|Firmicutes,25114@186801|Clostridia,3XZH2@572511|Blautia	186801|Clostridia	U	Belongs to the peptidase S26 family	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01409	33035.JPJF01000101_gene3272	0.0	873.0	COG1362@1|root,COG1362@2|Bacteria,1TP6G@1239|Firmicutes,2486Y@186801|Clostridia,3XZF0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	apeA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M18
NFNHFNFO_01410	33035.JPJF01000101_gene3273	0.0	2016.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,248VH@186801|Clostridia,3Y1CP@572511|Blautia	186801|Clostridia	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
NFNHFNFO_01411	33035.JPJF01000101_gene3274	3.82e-189	526.0	COG0395@1|root,COG0395@2|Bacteria,1TRGH@1239|Firmicutes,24C7R@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_01412	33035.JPJF01000101_gene3275	5.88e-199	552.0	COG1175@1|root,COG1175@2|Bacteria,1TSRA@1239|Firmicutes,24E4R@186801|Clostridia	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K17238	ko02010,map02010	M00207,M00599	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.38	-	-	BPD_transp_1
NFNHFNFO_01413	33035.JPJF01000101_gene3276	0.0	892.0	COG2182@1|root,COG2182@2|Bacteria,1UI1M@1239|Firmicutes,25EAR@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01414	33035.JPJF01000101_gene3277	1.94e-271	746.0	COG1653@1|root,COG1653@2|Bacteria,1V1YQ@1239|Firmicutes,24FS8@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
NFNHFNFO_01415	33035.JPJF01000101_gene3278	0.0	914.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TT52@1239|Firmicutes,249A9@186801|Clostridia,3Y0A4@572511|Blautia	186801|Clostridia	T	COG COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NFNHFNFO_01416	33035.JPJF01000101_gene3279	0.0	1110.0	COG2972@1|root,COG2972@2|Bacteria,1TW41@1239|Firmicutes,24AHF@186801|Clostridia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase,dCache_1
NFNHFNFO_01417	33035.JPJF01000101_gene3280	1.19e-175	489.0	COG0454@1|root,COG0456@2|Bacteria,1V37I@1239|Firmicutes,24IZQ@186801|Clostridia,3XZHS@572511|Blautia	186801|Clostridia	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_01418	33035.JPJF01000101_gene3281	4.2e-102	298.0	COG1695@1|root,COG1695@2|Bacteria,1V1R5@1239|Firmicutes,24FU3@186801|Clostridia,3XZWT@572511|Blautia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_34,PadR,Vir_act_alpha_C
NFNHFNFO_01419	33035.JPJF01000101_gene3282	3.7e-271	749.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3XYXA@572511|Blautia	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_01420	33035.JPJF01000101_gene3283	5.82e-108	315.0	COG1309@1|root,COG1309@2|Bacteria,1UQPP@1239|Firmicutes,24UJ4@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_4,TetR_N
NFNHFNFO_01421	33035.JPJF01000101_gene3284	3.34e-94	279.0	COG5660@1|root,COG5660@2|Bacteria,1VBBM@1239|Firmicutes,24NQV@186801|Clostridia	186801|Clostridia	S	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
NFNHFNFO_01422	33035.JPJF01000101_gene3286	0.0	976.0	COG2160@1|root,COG2160@2|Bacteria,1TPXC@1239|Firmicutes,24A08@186801|Clostridia,3XYUS@572511|Blautia	186801|Clostridia	G	Catalyzes the conversion of L-arabinose to L-ribulose	araA	-	5.3.1.4	ko:K01804	ko00040,ko01100,map00040,map01100	-	R01761	RC00516	ko00000,ko00001,ko01000	-	-	-	Arabinose_Iso_C,Arabinose_Isome
NFNHFNFO_01423	33035.JPJF01000101_gene3287	4.19e-267	735.0	COG3629@1|root,COG3629@2|Bacteria,1UUVJ@1239|Firmicutes,25KD9@186801|Clostridia,3Y0XS@572511|Blautia	186801|Clostridia	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD
NFNHFNFO_01424	537007.BLAHAN_06385	6.93e-42	138.0	COG1925@1|root,COG1925@2|Bacteria,1VA0R@1239|Firmicutes,24QIP@186801|Clostridia,3Y2CC@572511|Blautia	186801|Clostridia	G	PTS HPr component phosphorylation site	ptsH	-	-	ko:K11184,ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NFNHFNFO_01425	537007.BLAHAN_06386	1.15e-153	440.0	COG1481@1|root,COG1481@2|Bacteria,1TP2X@1239|Firmicutes,2484M@186801|Clostridia,3XYJH@572511|Blautia	186801|Clostridia	K	May be required for sporulation	whiA	-	-	ko:K09762	-	-	-	-	ko00000	-	-	-	HTH_WhiA,LAGLIDADG_WhiA,WhiA_N
NFNHFNFO_01426	33035.JPJF01000078_gene23	4.9e-208	575.0	COG1660@1|root,COG1660@2|Bacteria,1TPS4@1239|Firmicutes,248KQ@186801|Clostridia,3XZM6@572511|Blautia	186801|Clostridia	S	Displays ATPase and GTPase activities	yvcJ	-	-	ko:K06958	-	-	-	-	ko00000,ko03019	-	-	-	ATP_bind_2
NFNHFNFO_01427	33035.JPJF01000078_gene24	1.93e-187	523.0	COG0812@1|root,COG0812@2|Bacteria,1TP3W@1239|Firmicutes,247IU@186801|Clostridia,3XZDE@572511|Blautia	186801|Clostridia	M	UDP-N-acetylenolpyruvoylglucosamine reductase	murB	-	1.3.1.98	ko:K00075	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R03191,R03192	RC02639	ko00000,ko00001,ko01000,ko01011	-	-	-	FAD_binding_4,MurB_C
NFNHFNFO_01428	33035.JPJF01000105_gene1796	7.3e-169	473.0	COG1179@1|root,COG1179@2|Bacteria,1TQ7A@1239|Firmicutes,248RA@186801|Clostridia,3XZ1N@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	thiF	-	-	ko:K22132	-	-	-	-	ko00000,ko03016	-	-	-	ThiF
NFNHFNFO_01429	33035.JPJF01000105_gene1797	1.75e-75	226.0	2ANER@1|root,315MJ@2|Bacteria,1V6SU@1239|Firmicutes,24JBZ@186801|Clostridia,3Y07D@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spoVAE	-	-	ko:K06407	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
NFNHFNFO_01430	33035.JPJF01000105_gene1798	2.44e-242	666.0	COG0332@1|root,COG0332@2|Bacteria,1TPDE@1239|Firmicutes,25EAS@186801|Clostridia,3XZKI@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	spoVAD	-	-	ko:K06406	-	-	-	-	ko00000	-	-	-	SpoVAD
NFNHFNFO_01431	33035.JPJF01000105_gene1799	2e-106	307.0	2ANER@1|root,31DDD@2|Bacteria,1V46U@1239|Firmicutes,24JDI@186801|Clostridia,3Y02E@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spoVAC	-	-	ko:K06405	-	-	-	-	ko00000	-	-	-	SpoVAC_SpoVAEB
NFNHFNFO_01432	33035.JPJF01000105_gene1800	2.08e-132	376.0	COG2357@1|root,COG2357@2|Bacteria,1UZBZ@1239|Firmicutes,24FD2@186801|Clostridia,3XZXV@572511|Blautia	186801|Clostridia	S	Region found in RelA / SpoT proteins	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NFNHFNFO_01433	33035.JPJF01000105_gene1801	0.0	1511.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFNHFNFO_01434	33035.JPJF01000004_gene2022	8.72e-163	455.0	COG3822@1|root,COG3822@2|Bacteria,1UXBF@1239|Firmicutes,249XW@186801|Clostridia,3Y111@572511|Blautia	186801|Clostridia	S	Pfam:DUF1498	-	-	5.3.1.15	ko:K09988	ko00040,map00040	-	R01898	RC00516	ko00000,ko00001,ko01000	-	-	-	Lyx_isomer
NFNHFNFO_01435	33035.JPJF01000004_gene2021	0.0	950.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,24AWQ@186801|Clostridia,3Y0N7@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	DUF3502,SBP_bac_1,SBP_bac_8
NFNHFNFO_01436	33035.JPJF01000004_gene2020	1.09e-121	352.0	COG0395@1|root,COG0395@2|Bacteria,1TP1G@1239|Firmicutes,247T2@186801|Clostridia,3Y17J@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NFNHFNFO_01437	33035.JPJF01000004_gene2019	2.91e-45	154.0	COG4209@1|root,COG4209@2|Bacteria,1TQFY@1239|Firmicutes,24923@186801|Clostridia,3Y198@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NFNHFNFO_01439	33035.JPJF01000004_gene2018	7.03e-62	197.0	COG4942@1|root,COG4942@2|Bacteria	2|Bacteria	D	peptidase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PDDEXK_2
NFNHFNFO_01440	33035.JPJF01000004_gene2016	0.0	1012.0	2CK7V@1|root,2Z9WF@2|Bacteria,1TRYE@1239|Firmicutes,24E2Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01441	33035.JPJF01000004_gene2015	2.59e-267	739.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,248KF@186801|Clostridia,3Y1U6@572511|Blautia	186801|Clostridia	E	Cytosol aminopeptidase family, catalytic domain	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
NFNHFNFO_01442	33035.JPJF01000004_gene2014	0.0	1956.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,248VH@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolases family 38 C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
NFNHFNFO_01443	33035.JPJF01000004_gene2013	6.27e-295	808.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia	186801|Clostridia	G	family 4	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
NFNHFNFO_01444	33035.JPJF01000004_gene2010	0.0	899.0	COG1653@1|root,COG1653@2|Bacteria,1TTUX@1239|Firmicutes,25INP@186801|Clostridia,3Y22U@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01445	33035.JPJF01000004_gene1998	0.0	1469.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,248VH@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolases family 38 C-terminal domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
NFNHFNFO_01446	33035.JPJF01000004_gene1997	1.54e-309	843.0	COG3538@1|root,COG3538@2|Bacteria,1TRJI@1239|Firmicutes,248YF@186801|Clostridia,3Y17E@572511|Blautia	186801|Clostridia	S	Metal-independent alpha-mannosidase (GH125)	-	-	-	ko:K09704	-	-	-	-	ko00000	-	-	-	Glyco_hydro_125
NFNHFNFO_01447	33035.JPJF01000004_gene1995	1.32e-173	487.0	COG0266@1|root,COG0266@2|Bacteria,1TPM9@1239|Firmicutes,24BH2@186801|Clostridia	186801|Clostridia	L	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates	-	-	3.2.2.23,4.2.99.18	ko:K10563	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Fapy_DNA_glyco,H2TH,zf-FPG_IleRS
NFNHFNFO_01448	33035.JPJF01000004_gene1994	9.73e-55	171.0	COG3708@1|root,COG3708@2|Bacteria,1VFMZ@1239|Firmicutes,24RKD@186801|Clostridia	186801|Clostridia	K	Putative zinc ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Cass2,Zn_ribbon_2
NFNHFNFO_01449	33035.JPJF01000004_gene1993	1.97e-173	488.0	COG2378@1|root,COG2378@2|Bacteria,1TS78@1239|Firmicutes,25C7I@186801|Clostridia	186801|Clostridia	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL,Zn_ribbon_2
NFNHFNFO_01450	33035.JPJF01000004_gene1992	2.6e-82	244.0	2AF43@1|root,3152T@2|Bacteria,1VFMI@1239|Firmicutes,24RBI@186801|Clostridia,3Y0C4@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06404	-	-	-	-	ko00000	-	-	-	SpoVAB
NFNHFNFO_01451	33035.JPJF01000004_gene1991	1.08e-135	385.0	28PNE@1|root,2ZCB6@2|Bacteria,1V214@1239|Firmicutes,24DN2@186801|Clostridia,3XZTN@572511|Blautia	186801|Clostridia	S	Psort location	spoVAA	-	-	ko:K06403	-	-	-	-	ko00000	-	-	-	SporV_AA
NFNHFNFO_01452	33035.JPJF01000004_gene1990	1.17e-156	441.0	COG1191@1|root,COG1191@2|Bacteria,1TP3Q@1239|Firmicutes,2487Z@186801|Clostridia,3XZEX@572511|Blautia	186801|Clostridia	K	COG COG1191 DNA-directed RNA polymerase specialized sigma subunit	sigF	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
NFNHFNFO_01453	33035.JPJF01000004_gene1989	5.78e-97	282.0	COG2172@1|root,COG2172@2|Bacteria,1V6V2@1239|Firmicutes,24JPT@186801|Clostridia,3Y0A1@572511|Blautia	186801|Clostridia	H	Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti-anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition	spoIIAB	-	2.7.11.1	ko:K06379	-	-	-	-	ko00000,ko01000	-	-	-	HATPase_c_2
NFNHFNFO_01454	33035.JPJF01000004_gene1988	1.6e-65	199.0	COG1366@1|root,COG1366@2|Bacteria,1VENG@1239|Firmicutes,24R0X@186801|Clostridia,3Y0KP@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	spoIIAA	-	-	ko:K06378	-	-	-	-	ko00000	-	-	-	STAS
NFNHFNFO_01455	33035.JPJF01000004_gene1987	1.6e-291	806.0	COG3063@1|root,COG3063@2|Bacteria,1UY48@1239|Firmicutes,24AGF@186801|Clostridia,3XYR7@572511|Blautia	186801|Clostridia	NU	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_6,TPR_8
NFNHFNFO_01456	33035.JPJF01000004_gene1986	2.55e-28	101.0	2EGDA@1|root,33A54@2|Bacteria,1VKC8@1239|Firmicutes,258G8@186801|Clostridia,3Y0SU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01457	33035.JPJF01000004_gene1985	1.4e-299	818.0	COG0285@1|root,COG0285@2|Bacteria,1TPX5@1239|Firmicutes,247PC@186801|Clostridia,3XZC1@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	folC	-	6.3.2.12,6.3.2.17	ko:K11754	ko00790,ko01100,map00790,map01100	M00126,M00841	R00942,R02237,R04241	RC00064,RC00090,RC00162	ko00000,ko00001,ko00002,ko01000	-	-	-	Mur_ligase_C,Mur_ligase_M
NFNHFNFO_01458	33035.JPJF01000004_gene1984	0.0	1332.0	COG1368@1|root,COG1368@2|Bacteria,1TQYQ@1239|Firmicutes,25CNS@186801|Clostridia,3XYIH@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Sulfatase
NFNHFNFO_01459	33035.JPJF01000004_gene1983	0.0	1712.0	COG0525@1|root,COG0525@2|Bacteria,1TPN4@1239|Firmicutes,248VC@186801|Clostridia,3XYWB@572511|Blautia	186801|Clostridia	J	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner	valS	-	6.1.1.9	ko:K01873	ko00970,map00970	M00359,M00360	R03665	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,Val_tRNA-synt_C,tRNA-synt_1
NFNHFNFO_01460	33035.JPJF01000004_gene1974	1.85e-35	121.0	2EIJI@1|root,33CAV@2|Bacteria,1VK5E@1239|Firmicutes,24MMQ@186801|Clostridia,3Y0TE@572511|Blautia	186801|Clostridia	S	COG NOG17864 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	SASP
NFNHFNFO_01461	33035.JPJF01000004_gene1973	4.14e-119	350.0	COG2340@1|root,COG2340@2|Bacteria,1V6GZ@1239|Firmicutes,24BAQ@186801|Clostridia	186801|Clostridia	V	PFAM SCP-like extracellular	safA	-	-	-	-	-	-	-	-	-	-	-	CAP,LysM
NFNHFNFO_01462	1232449.BAHV02000007_gene807	4.73e-238	665.0	COG0534@1|root,COG0534@2|Bacteria,1VS1B@1239|Firmicutes	1239|Firmicutes	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_01463	1232449.BAHV02000007_gene806	8.04e-76	234.0	COG1309@1|root,COG1309@2|Bacteria,1V6GJ@1239|Firmicutes,24J0S@186801|Clostridia,269CC@186813|unclassified Clostridiales	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_01464	33035.JPJF01000004_gene1972	4.44e-28	101.0	COG1983@1|root,COG1983@2|Bacteria,1TUCF@1239|Firmicutes,25PAV@186801|Clostridia,3Y0SN@572511|Blautia	186801|Clostridia	KT	PspC domain	-	-	-	-	-	-	-	-	-	-	-	-	PspC
NFNHFNFO_01465	33035.JPJF01000004_gene1971	9.29e-124	362.0	2E3J1@1|root,32YHG@2|Bacteria,1VF3S@1239|Firmicutes,25E89@186801|Clostridia,3Y0KC@572511|Blautia	186801|Clostridia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
NFNHFNFO_01466	33035.JPJF01000004_gene1970	3.18e-104	311.0	COG4709@1|root,COG4709@2|Bacteria,1VETQ@1239|Firmicutes,24G3G@186801|Clostridia,3Y0B4@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NFNHFNFO_01467	33035.JPJF01000004_gene1969	2.83e-69	209.0	COG1695@1|root,COG1695@2|Bacteria,1VACN@1239|Firmicutes,24MRF@186801|Clostridia,3Y09J@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
NFNHFNFO_01468	33035.JPJF01000004_gene1968	1.67e-119	343.0	2ADW4@1|root,313N4@2|Bacteria,1V790@1239|Firmicutes	1239|Firmicutes	S	Protein of unknown function (DUF4230)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4230
NFNHFNFO_01469	33035.JPJF01000004_gene1967	0.0	1081.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XYGZ@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147,ko:K11085	ko02010,map02010	-	-	-	ko00000,ko00001,ko01000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFNHFNFO_01470	33035.JPJF01000004_gene1966	0.0	1032.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XYTP@572511|Blautia	186801|Clostridia	V	COG COG1132 ABC-type multidrug transport system, ATPase and permease components	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFNHFNFO_01471	658655.HMPREF0988_02860	1.94e-51	194.0	COG2972@1|root,COG2972@2|Bacteria,1UW47@1239|Firmicutes,25KQI@186801|Clostridia,27RWA@186928|unclassified Lachnospiraceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NFNHFNFO_01473	697281.Mahau_0700	3.23e-172	490.0	COG4030@1|root,COG4030@2|Bacteria,1TRZY@1239|Firmicutes,249GP@186801|Clostridia,42HQP@68295|Thermoanaerobacterales	186801|Clostridia	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
NFNHFNFO_01474	1280680.AUJU01000008_gene189	4.35e-130	380.0	COG4608@1|root,COG4608@2|Bacteria,1UX9A@1239|Firmicutes,24Z8K@186801|Clostridia,4BYN2@830|Butyrivibrio	186801|Clostridia	E	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
NFNHFNFO_01475	1280673.AUJJ01000001_gene2217	7.73e-133	387.0	COG0444@1|root,COG0444@2|Bacteria,1UX99@1239|Firmicutes,25KBT@186801|Clostridia,4BWQT@830|Butyrivibrio	186801|Clostridia	EP	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
NFNHFNFO_01476	1122132.AQYH01000004_gene1674	6.87e-99	298.0	COG1173@1|root,COG1173@2|Bacteria,1R4DJ@1224|Proteobacteria,2U44U@28211|Alphaproteobacteria,4B9Q2@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NFNHFNFO_01477	1122132.AQYH01000004_gene1675	1.03e-84	261.0	COG0601@1|root,COG0601@2|Bacteria,1QDMV@1224|Proteobacteria,2TTGN@28211|Alphaproteobacteria,4B6XV@82115|Rhizobiaceae	28211|Alphaproteobacteria	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NFNHFNFO_01478	397287.C807_02114	2.48e-207	587.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia,27K17@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
NFNHFNFO_01479	33035.JPJF01000037_gene2909	0.0	944.0	COG0791@1|root,COG3266@1|root,COG3584@1|root,COG0791@2|Bacteria,COG3266@2|Bacteria,COG3584@2|Bacteria,1TSZ0@1239|Firmicutes,25B1S@186801|Clostridia,3Y1DB@572511|Blautia	186801|Clostridia	M	3D domain	-	-	3.4.14.13	ko:K20742	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	3D,NLPC_P60,SH3_3
NFNHFNFO_01480	33035.JPJF01000037_gene2910	2.79e-49	156.0	COG2827@1|root,COG2827@2|Bacteria,1VEZF@1239|Firmicutes,24QYU@186801|Clostridia,3Y0F0@572511|Blautia	186801|Clostridia	L	endonuclease containing a URI domain	-	-	-	ko:K07461	-	-	-	-	ko00000	-	-	-	GIY-YIG
NFNHFNFO_01481	33035.JPJF01000037_gene2911	2.9e-93	276.0	2DTES@1|root,33K1J@2|Bacteria,1UDZV@1239|Firmicutes,24VSS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01483	33035.JPJF01000037_gene2912	0.0	1066.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NFNHFNFO_01484	33035.JPJF01000037_gene2913	6.15e-293	809.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSBI@1239|Firmicutes,24E47@186801|Clostridia,3XZZ0@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
NFNHFNFO_01485	33035.JPJF01000037_gene2914	1.56e-296	812.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24977@186801|Clostridia	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_01486	33035.JPJF01000037_gene2915	3.15e-199	553.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3XYIT@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_01487	33035.JPJF01000037_gene2916	3.6e-178	498.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3XZD4@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10119,ko:K10202	ko02010,map02010	M00196,M00205	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.18,3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_01488	33035.JPJF01000037_gene2917	0.0	1132.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3XZXF@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NFNHFNFO_01489	33035.JPJF01000037_gene2917	4.09e-39	144.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3XZXF@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NFNHFNFO_01490	33035.JPJF01000037_gene2918	2.51e-159	449.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3XYM7@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short,adh_short_C2
NFNHFNFO_01491	33035.JPJF01000037_gene2919	6e-247	680.0	COG1820@1|root,COG1820@2|Bacteria,1TPFK@1239|Firmicutes,2481N@186801|Clostridia,3XYYH@572511|Blautia	186801|Clostridia	G	Belongs to the metallo-dependent hydrolases superfamily. NagA family	nagA	-	3.5.1.25	ko:K01443	ko00520,ko01130,map00520,map01130	-	R02059	RC00166,RC00300	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NFNHFNFO_01492	33035.JPJF01000037_gene2920	5.85e-159	446.0	COG3010@1|root,COG3010@2|Bacteria,1TSR7@1239|Firmicutes,24AVB@186801|Clostridia,3XZHW@572511|Blautia	186801|Clostridia	G	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)	nanE	-	5.1.3.9	ko:K01788	ko00520,map00520	-	R02087	RC00290	ko00000,ko00001,ko01000	-	-	-	NanE
NFNHFNFO_01493	33035.JPJF01000037_gene2921	7.76e-213	589.0	COG0329@1|root,COG0329@2|Bacteria,1TQRK@1239|Firmicutes,247ZW@186801|Clostridia,3XZN3@572511|Blautia	186801|Clostridia	EM	Belongs to the DapA family	-	-	4.1.3.3	ko:K01639	ko00520,map00520	-	R01811	RC00159,RC00600	ko00000,ko00001,ko01000	-	-	-	DHDPS
NFNHFNFO_01494	33035.JPJF01000037_gene2922	0.0	925.0	COG0591@1|root,COG0591@2|Bacteria,1TQCK@1239|Firmicutes,25E9U@186801|Clostridia,3Y134@572511|Blautia	186801|Clostridia	E	Sodium:solute symporter family	sglT	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
NFNHFNFO_01495	33035.JPJF01000037_gene2923	7.27e-106	305.0	COG2731@1|root,COG2731@2|Bacteria,1V3S9@1239|Firmicutes,24HIS@186801|Clostridia,3Y1K1@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF386)	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
NFNHFNFO_01496	33035.JPJF01000037_gene2924	6.78e-180	503.0	COG1940@1|root,COG1940@2|Bacteria,1TP04@1239|Firmicutes,248SD@186801|Clostridia,3XZGU@572511|Blautia	186801|Clostridia	GK	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	ROK
NFNHFNFO_01497	33035.JPJF01000037_gene2925	4.78e-182	508.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia,3XZRH@572511|Blautia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NFNHFNFO_01498	33035.JPJF01000037_gene2926	1.86e-94	275.0	COG0735@1|root,COG0735@2|Bacteria,1V400@1239|Firmicutes,24JS4@186801|Clostridia,3Y0CR@572511|Blautia	186801|Clostridia	P	Belongs to the Fur family	perR	-	-	ko:K09825	-	-	-	-	ko00000,ko03000	-	-	-	FUR
NFNHFNFO_01499	33035.JPJF01000037_gene2927	2.46e-126	359.0	COG1592@1|root,COG1592@2|Bacteria,1TSUY@1239|Firmicutes,248GY@186801|Clostridia,3XYT1@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	rbr3A	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
NFNHFNFO_01500	33035.JPJF01000037_gene2928	5.35e-125	356.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,3XZBD@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	rbr	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
NFNHFNFO_01501	411463.EUBVEN_02390	1.77e-73	283.0	COG2247@1|root,COG3064@1|root,COG4733@1|root,COG2247@2|Bacteria,COG3064@2|Bacteria,COG4733@2|Bacteria,1VDKU@1239|Firmicutes,24PKK@186801|Clostridia,25XFG@186806|Eubacteriaceae	186801|Clostridia	M	Fibronectin type 3 domain	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01502	500632.CLONEX_02596	1.26e-216	645.0	COG2247@1|root,COG2247@2|Bacteria,1W188@1239|Firmicutes,25F2J@186801|Clostridia	186801|Clostridia	M	Leucine-rich repeat (LRR) protein	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,DUF4430,Prenyltrans
NFNHFNFO_01503	33035.JPJF01000037_gene2929	2.79e-143	422.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3XZ8B@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NFNHFNFO_01504	33035.JPJF01000037_gene2929	6.66e-175	506.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3XZ8B@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NFNHFNFO_01505	500632.CLONEX_02597	4.35e-106	317.0	COG1657@1|root,COG1657@2|Bacteria,1VBUR@1239|Firmicutes,24F29@186801|Clostridia	186801|Clostridia	I	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
NFNHFNFO_01506	537007.BLAHAN_06825	7.02e-158	449.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,3XZVA@572511|Blautia	186801|Clostridia	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
NFNHFNFO_01507	500632.CLONEX_02599	0.0	894.0	COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia	186801|Clostridia	G	abc transporter atp-binding protein	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF-ribofla_trS,ECF_trnsprt
NFNHFNFO_01508	500632.CLONEX_02600	9.42e-223	625.0	COG4720@1|root,COG4720@2|Bacteria,1V2DR@1239|Firmicutes,249XR@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF-ribofla_trS,ECF_trnsprt
NFNHFNFO_01509	556261.HMPREF0240_00904	5.97e-42	152.0	COG4886@1|root,COG4886@2|Bacteria,1V44C@1239|Firmicutes,25EA1@186801|Clostridia,36UPC@31979|Clostridiaceae	186801|Clostridia	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,LRR_5
NFNHFNFO_01510	556261.HMPREF0240_04367	5.47e-231	646.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,36DT9@31979|Clostridiaceae	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_01511	476272.RUMHYD_03470	3.99e-165	474.0	COG1940@1|root,COG1940@2|Bacteria,1VQW7@1239|Firmicutes,24YU9@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
NFNHFNFO_01512	476272.RUMHYD_03469	3.32e-164	466.0	COG1940@1|root,COG1940@2|Bacteria,1V1EQ@1239|Firmicutes,24FHR@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	2.7.1.55	ko:K00881	ko00051,ko01120,map00051,map01120	-	R03576	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	ROK
NFNHFNFO_01513	33035.JPJF01000037_gene2930	0.0	1165.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3XZ8U@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	ams	-	2.4.1.4,3.2.1.1,5.4.99.16	ko:K05341,ko:K05343	ko00500,ko01100,map00500,map01100	-	R01557,R01823,R02108,R02112,R11262	RC00028,RC01816	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase
NFNHFNFO_01514	33035.JPJF01000037_gene2945	2.05e-153	431.0	COG1272@1|root,COG1272@2|Bacteria,1TSFK@1239|Firmicutes,24CPT@186801|Clostridia,3XYGI@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yqfA	-	-	ko:K11068	-	-	-	-	ko00000,ko02042	-	-	-	HlyIII
NFNHFNFO_01515	33035.JPJF01000037_gene2946	0.0	1500.0	COG0642@1|root,COG0642@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,3Y102@572511|Blautia	186801|Clostridia	T	Bacterial extracellular solute-binding proteins, family 3	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
NFNHFNFO_01516	33035.JPJF01000037_gene2947	0.0	1433.0	COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,247J6@186801|Clostridia	186801|Clostridia	G	hydrolase, family 65, central catalytic	-	-	2.4.1.64	ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
NFNHFNFO_01517	33035.JPJF01000037_gene2948	7.03e-132	376.0	COG0637@1|root,COG0637@2|Bacteria,1UZE0@1239|Firmicutes,24DWR@186801|Clostridia	186801|Clostridia	S	Haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
NFNHFNFO_01518	33035.JPJF01000037_gene2949	1.03e-139	395.0	COG0110@1|root,COG0110@2|Bacteria,1TQQB@1239|Firmicutes,25B1T@186801|Clostridia,3Y2DW@572511|Blautia	186801|Clostridia	S	Maltose acetyltransferase	-	-	2.3.1.18	ko:K00633	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Mac
NFNHFNFO_01520	33035.JPJF01000037_gene2951	1.04e-251	689.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia,3Y1E6@572511|Blautia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_01521	33035.JPJF01000037_gene2952	0.0	895.0	COG2508@1|root,COG2508@2|Bacteria	2|Bacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
NFNHFNFO_01522	33035.JPJF01000037_gene2953	0.0	920.0	COG2508@1|root,COG2508@2|Bacteria,1VIT3@1239|Firmicutes,24JXW@186801|Clostridia,3Y0T9@572511|Blautia	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NFNHFNFO_01523	33035.JPJF01000037_gene2954	1.77e-135	385.0	COG5012@1|root,COG5012@2|Bacteria,1VSJU@1239|Firmicutes,24XK2@186801|Clostridia,3Y145@572511|Blautia	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
NFNHFNFO_01524	33035.JPJF01000037_gene2955	5.33e-128	363.0	COG5423@1|root,COG5423@2|Bacteria,1V8Y4@1239|Firmicutes,24EAF@186801|Clostridia,3Y1BP@572511|Blautia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NFNHFNFO_01525	33035.JPJF01000037_gene2956	0.0	1088.0	COG0633@1|root,COG3894@1|root,COG0633@2|Bacteria,COG3894@2|Bacteria,1TP0H@1239|Firmicutes,247S0@186801|Clostridia,3Y14F@572511|Blautia	186801|Clostridia	C	Domain of unknown function (DUF4445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4445,Fer2
NFNHFNFO_01526	33035.JPJF01000037_gene2957	0.0	1387.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,3XYN9@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase,PRK
NFNHFNFO_01527	33035.JPJF01000037_gene2969	9.74e-138	390.0	COG5012@1|root,COG5012@2|Bacteria,1V1P0@1239|Firmicutes,24G08@186801|Clostridia,3Y0XR@572511|Blautia	186801|Clostridia	S	B12 binding domain	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
NFNHFNFO_01528	33035.JPJF01000037_gene2970	6.56e-185	515.0	COG1410@1|root,COG1410@2|Bacteria,1UV7K@1239|Firmicutes,25CEH@186801|Clostridia,3Y0ZA@572511|Blautia	186801|Clostridia	E	Pterin binding enzyme	-	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	Pterin_bind
NFNHFNFO_01529	33035.JPJF01000037_gene2971	1.24e-228	631.0	COG1609@1|root,COG1609@2|Bacteria,1TS5M@1239|Firmicutes,24AWP@186801|Clostridia,3Y018@572511|Blautia	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_01530	33035.JPJF01000037_gene2972	8.29e-293	802.0	COG1653@1|root,COG1653@2|Bacteria,1TQFZ@1239|Firmicutes,25MFS@186801|Clostridia,3Y1U2@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_01531	33035.JPJF01000037_gene2973	5.22e-229	638.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,3Y1I8@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10237	ko02010,map02010	M00204,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.17	-	-	BPD_transp_1
NFNHFNFO_01532	33035.JPJF01000037_gene2974	2.1e-183	511.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia,3Y0HM@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_01533	33035.JPJF01000037_gene2975	0.0	1092.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3XZ6T@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.2.1.1	ko:K01176	ko00500,ko01100,ko04973,map00500,map01100,map04973	-	R02108,R02112,R11262	-	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,Malt_amylase_C
NFNHFNFO_01534	33035.JPJF01000037_gene2976	4.31e-143	409.0	COG5464@1|root,COG5464@2|Bacteria,1UZWF@1239|Firmicutes,25D0T@186801|Clostridia	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NFNHFNFO_01535	33035.JPJF01000037_gene2977	1.39e-251	690.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_01536	33035.JPJF01000037_gene2978	8.01e-266	729.0	COG1940@1|root,COG1940@2|Bacteria,1UY4P@1239|Firmicutes,24E3X@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
NFNHFNFO_01537	33035.JPJF01000037_gene2979	2.91e-268	736.0	COG1846@1|root,COG1940@1|root,COG1846@2|Bacteria,COG1940@2|Bacteria,1UY4P@1239|Firmicutes,24E3X@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
NFNHFNFO_01538	33035.JPJF01000037_gene2980	5.58e-248	680.0	COG0673@1|root,COG0673@2|Bacteria,1TSCE@1239|Firmicutes,24BFP@186801|Clostridia	186801|Clostridia	S	Oxidoreductase NAD-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_01539	33035.JPJF01000037_gene2981	2.92e-292	799.0	COG1653@1|root,COG1653@2|Bacteria,1VR2M@1239|Firmicutes,24YJT@186801|Clostridia,3Y1T3@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_01540	33035.JPJF01000037_gene2982	5.42e-200	555.0	COG1175@1|root,COG1175@2|Bacteria,1TP1Q@1239|Firmicutes,24ADV@186801|Clostridia	186801|Clostridia	P	Abc transporter, permease protein	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_01541	33035.JPJF01000037_gene2983	7.08e-186	518.0	COG0395@1|root,COG0395@2|Bacteria,1V090@1239|Firmicutes,2493G@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_01542	33035.JPJF01000037_gene2984	1.02e-195	543.0	COG1082@1|root,COG1082@2|Bacteria,1UYTA@1239|Firmicutes,24CXC@186801|Clostridia	186801|Clostridia	G	AP endonuclease family	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NFNHFNFO_01543	33035.JPJF01000037_gene2985	2.22e-132	378.0	COG5578@1|root,COG5578@2|Bacteria,1V5CK@1239|Firmicutes,24IZD@186801|Clostridia,3Y1SW@572511|Blautia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
NFNHFNFO_01544	33035.JPJF01000037_gene2986	5.74e-289	794.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,248X0@186801|Clostridia,3Y14V@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_01545	33035.JPJF01000037_gene2987	4.74e-202	560.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,3Y176@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_01546	33035.JPJF01000037_gene2988	4.06e-172	482.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia,3Y0FC@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_01547	33035.JPJF01000037_gene2989	0.0	1422.0	COG3345@1|root,COG3345@2|Bacteria,1TQF4@1239|Firmicutes,2489F@186801|Clostridia,3XZMS@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolase family 36 N-terminal domain	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_36C,Glyco_hydro_36N,Melibiase
NFNHFNFO_01548	33035.JPJF01000037_gene2990	5.32e-222	612.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,3XZEN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_01549	33035.JPJF01000037_gene2991	9.89e-76	233.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,3XZEN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_01550	33035.JPJF01000037_gene2992	5.81e-166	466.0	COG4586@1|root,COG4586@2|Bacteria,1TP1N@1239|Firmicutes,247KC@186801|Clostridia	186801|Clostridia	S	PFAM ABC transporter	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_01551	33035.JPJF01000037_gene2993	2.75e-172	482.0	COG4587@1|root,COG4587@2|Bacteria,1TSAN@1239|Firmicutes,24B28@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
NFNHFNFO_01552	33035.JPJF01000037_gene2994	1.19e-175	491.0	COG3694@1|root,COG3694@2|Bacteria,1TR4N@1239|Firmicutes,24A3T@186801|Clostridia	186801|Clostridia	S	transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_6
NFNHFNFO_01554	33035.JPJF01000037_gene2995	2.24e-126	360.0	2C6ZI@1|root,31XAP@2|Bacteria,1V8Q3@1239|Firmicutes,24R7B@186801|Clostridia,3Y0WJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01555	33035.JPJF01000037_gene2996	2.3e-77	252.0	2FII4@1|root,34AA6@2|Bacteria,1W0M0@1239|Firmicutes,253B6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01561	1235798.C817_05702	6.38e-65	211.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,248JG@186801|Clostridia,27WKG@189330|Dorea	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,HhH-GPD,Transposase_20
NFNHFNFO_01562	478749.BRYFOR_07503	2.6e-33	123.0	COG1396@1|root,COG1396@2|Bacteria,1VEU8@1239|Firmicutes,24QN0@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NFNHFNFO_01563	478749.BRYFOR_07230	2.59e-89	266.0	COG4636@1|root,COG4636@2|Bacteria,1V1QN@1239|Firmicutes,25DNV@186801|Clostridia	186801|Clostridia	S	Putative restriction endonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Uma2
NFNHFNFO_01564	658088.HMPREF0987_00026	5.62e-193	554.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,27J3U@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NFNHFNFO_01565	33035.JPJF01000080_gene127	8.21e-85	260.0	COG3409@1|root,COG3409@2|Bacteria,1TS29@1239|Firmicutes,247SQ@186801|Clostridia,3XZDX@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	sleC	-	-	-	-	-	-	-	-	-	-	-	PG_binding_1,SpoIID
NFNHFNFO_01566	33035.JPJF01000080_gene128	1.03e-280	770.0	COG0750@1|root,COG0750@2|Bacteria,1TPMC@1239|Firmicutes,247MT@186801|Clostridia,3XYIX@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	rseP	-	-	ko:K11749	ko02024,ko04112,map02024,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	PDZ,PDZ_2,Peptidase_M50
NFNHFNFO_01567	33035.JPJF01000080_gene129	5.48e-261	716.0	COG0743@1|root,COG0743@2|Bacteria,1TP1C@1239|Firmicutes,2483M@186801|Clostridia,3XYJF@572511|Blautia	186801|Clostridia	H	Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP)	dxr	-	1.1.1.267	ko:K00099	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05688	RC01452	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06420	DXPR_C,DXP_redisom_C,DXP_reductoisom
NFNHFNFO_01568	33035.JPJF01000080_gene130	2.71e-171	480.0	COG0575@1|root,COG0575@2|Bacteria,1UPNB@1239|Firmicutes,248BP@186801|Clostridia,3XZGP@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score 10.00	cdsA	-	2.7.7.41	ko:K00981	ko00564,ko01100,ko01110,ko04070,map00564,map01100,map01110,map04070	M00093	R01799	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	CTP_transf_1
NFNHFNFO_01569	33035.JPJF01000080_gene131	1.61e-162	455.0	COG0020@1|root,COG0020@2|Bacteria,1TQTS@1239|Firmicutes,247TE@186801|Clostridia,3XYZ5@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids	uppS	-	2.5.1.31	ko:K00806	ko00900,ko01110,map00900,map01110	-	R06447	RC00279,RC02839	ko00000,ko00001,ko01000,ko01006	-	-	-	Prenyltransf
NFNHFNFO_01570	33035.JPJF01000080_gene132	1.94e-118	340.0	COG0233@1|root,COG0233@2|Bacteria,1V1F2@1239|Firmicutes,24HWS@186801|Clostridia,3XZAV@572511|Blautia	186801|Clostridia	J	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another	frr	-	-	ko:K02838	-	-	-	-	ko00000,ko03012	-	-	-	RRF
NFNHFNFO_01571	33035.JPJF01000080_gene133	3.26e-160	449.0	COG0528@1|root,COG0528@2|Bacteria,1TPXN@1239|Firmicutes,247KR@186801|Clostridia,3XZ3X@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible phosphorylation of UMP to UDP	pyrH	-	2.7.4.22	ko:K09903	ko00240,ko01100,map00240,map01100	-	R00158	RC00002	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NFNHFNFO_01572	33035.JPJF01000080_gene134	7.66e-70	211.0	COG2198@1|root,COG2198@2|Bacteria,1TUB6@1239|Firmicutes,257TB@186801|Clostridia,3Y0UT@572511|Blautia	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
NFNHFNFO_01573	33035.JPJF01000080_gene135	5.48e-315	859.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3XYY1@572511|Blautia	186801|Clostridia	P	COG COG0733 Na -dependent transporters of the SNF family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NFNHFNFO_01574	33035.JPJF01000080_gene136	1.62e-231	639.0	COG3081@1|root,COG3081@2|Bacteria,1TSR5@1239|Firmicutes,25CG3@186801|Clostridia,3Y16K@572511|Blautia	186801|Clostridia	S	37-kD nucleoid-associated bacterial protein	-	-	-	-	-	-	-	-	-	-	-	-	NA37
NFNHFNFO_01575	33035.JPJF01000080_gene137	0.0	2072.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,24819@186801|Clostridia,3XZCA@572511|Blautia	186801|Clostridia	F	Carbamoyl-phosphate synthetase large chain, oligomerisation domain	carB2	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,MGS
NFNHFNFO_01576	33035.JPJF01000080_gene138	4.75e-199	554.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,3XZ7M@572511|Blautia	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_01577	33035.JPJF01000080_gene139	4.93e-117	337.0	COG1878@1|root,COG1878@2|Bacteria,1VDFH@1239|Firmicutes,25CZC@186801|Clostridia	186801|Clostridia	S	Putative cyclase	-	-	3.5.1.9	ko:K07130	ko00380,ko00630,ko01100,map00380,map00630,map01100	M00038	R00988,R01959,R04911	RC00263,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	Cyclase
NFNHFNFO_01578	33035.JPJF01000080_gene140	8.43e-127	364.0	COG0546@1|root,COG0546@2|Bacteria,1V1FQ@1239|Firmicutes,24G1U@186801|Clostridia,3XZY6@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	nt5e	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NFNHFNFO_01579	33035.JPJF01000080_gene141	8.38e-313	853.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3XZ7G@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_01580	33035.JPJF01000080_gene142	3.6e-144	410.0	COG3022@1|root,COG3022@2|Bacteria,1TR33@1239|Firmicutes,248N1@186801|Clostridia,3XZWC@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K09861	-	-	-	-	ko00000	-	-	-	H2O2_YaaD
NFNHFNFO_01581	33035.JPJF01000080_gene143	3.91e-144	408.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia,3Y1GD@572511|Blautia	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Mannitol_dh_C
NFNHFNFO_01582	33035.JPJF01000080_gene144	2.37e-76	226.0	COG2158@1|root,COG2158@2|Bacteria,1VFNA@1239|Firmicutes,24MYB@186801|Clostridia,3Y0C2@572511|Blautia	186801|Clostridia	S	Cysteine-rich small domain	-	-	-	ko:K07162	-	-	-	-	ko00000	-	-	-	zf-like
NFNHFNFO_01583	33035.JPJF01000080_gene145	9.42e-95	276.0	COG2703@1|root,COG2703@2|Bacteria,1VAI0@1239|Firmicutes,24MQU@186801|Clostridia,3XZZH@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07216	-	-	-	-	ko00000	-	-	-	Hemerythrin
NFNHFNFO_01584	33035.JPJF01000080_gene146	0.0	2230.0	COG0642@1|root,COG2199@1|root,COG0642@2|Bacteria,COG2199@2|Bacteria,1TS5J@1239|Firmicutes,25EAF@186801|Clostridia	186801|Clostridia	T	Diguanylate cyclase (GGDEF) domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,GAF,GGDEF,HAMP,HATPase_c,HisKA,PAS_3,PAS_9,Pkinase,Response_reg,SBP_bac_3,dCache_1
NFNHFNFO_01585	33035.JPJF01000080_gene147	1.99e-205	579.0	COG1653@1|root,COG1653@2|Bacteria,1TRST@1239|Firmicutes,24APZ@186801|Clostridia	186801|Clostridia	G	COG COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
NFNHFNFO_01586	33035.JPJF01000080_gene147	2.37e-33	127.0	COG1653@1|root,COG1653@2|Bacteria,1TRST@1239|Firmicutes,24APZ@186801|Clostridia	186801|Clostridia	G	COG COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
NFNHFNFO_01587	33035.JPJF01000080_gene147	5.45e-35	132.0	COG1653@1|root,COG1653@2|Bacteria,1TRST@1239|Firmicutes,24APZ@186801|Clostridia	186801|Clostridia	G	COG COG1653 ABC-type sugar transport system, periplasmic component	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
NFNHFNFO_01588	33035.JPJF01000080_gene148	1.04e-253	699.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,3XYZZ@572511|Blautia	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	-	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
NFNHFNFO_01589	33035.JPJF01000080_gene149	3.22e-117	339.0	2E5I1@1|root,3309D@2|Bacteria,1VG10@1239|Firmicutes,24NJJ@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	YhhN
NFNHFNFO_01590	33035.JPJF01000080_gene150	6.84e-281	772.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,3Y02A@572511|Blautia	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_01591	33035.JPJF01000080_gene151	1.78e-87	258.0	COG1846@1|root,COG1846@2|Bacteria,1VDF4@1239|Firmicutes,24NPM@186801|Clostridia	186801|Clostridia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	MarR
NFNHFNFO_01592	1123075.AUDP01000003_gene523	3.3e-162	468.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3WGNK@541000|Ruminococcaceae	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NFNHFNFO_01593	180332.JTGN01000007_gene3514	1.33e-112	328.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia	186801|Clostridia	V	ABC transporter	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_01594	180332.JTGN01000007_gene3513	2.32e-129	416.0	COG0845@1|root,COG4733@1|root,COG0845@2|Bacteria,COG4733@2|Bacteria,1TT2M@1239|Firmicutes,24BJV@186801|Clostridia	186801|Clostridia	M	Efflux transporter, RND family, MFP subunit	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NFNHFNFO_01595	537007.BLAHAN_05726	1.28e-161	452.0	COG0822@1|root,COG0822@2|Bacteria,1TQEQ@1239|Firmicutes,248ID@186801|Clostridia,3XYM6@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NifU_N
NFNHFNFO_01596	33035.JPJF01000080_gene153	6.91e-235	647.0	2C4R5@1|root,2Z7JK@2|Bacteria,1TQIE@1239|Firmicutes,24879@186801|Clostridia,3XZAX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GGGtGRT
NFNHFNFO_01597	1232447.BAHW02000022_gene1363	1.44e-41	139.0	2DMWG@1|root,32U3S@2|Bacteria,1VA7F@1239|Firmicutes,24MP5@186801|Clostridia	186801|Clostridia	S	YmaF family	-	-	-	-	-	-	-	-	-	-	-	-	YmaF
NFNHFNFO_01598	1235802.C823_01019	1.2e-26	99.0	COG3655@1|root,COG3655@2|Bacteria,1VM6P@1239|Firmicutes,24UWM@186801|Clostridia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
NFNHFNFO_01599	33035.JPJF01000080_gene154	1.5e-172	481.0	COG0846@1|root,COG0846@2|Bacteria,1V41R@1239|Firmicutes,24I6F@186801|Clostridia,3Y1ED@572511|Blautia	186801|Clostridia	K	Sir2 family	-	-	-	-	-	-	-	-	-	-	-	-	SIR2
NFNHFNFO_01600	33035.JPJF01000080_gene155	1.36e-82	250.0	2EI6Y@1|root,33BYA@2|Bacteria,1VNP8@1239|Firmicutes,24URC@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
NFNHFNFO_01601	33035.JPJF01000080_gene156	2.83e-182	509.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3XYSB@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_01602	33035.JPJF01000080_gene157	9.53e-76	227.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,3Y08N@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NFNHFNFO_01603	33035.JPJF01000080_gene158	1.7e-195	559.0	COG3266@1|root,COG3266@2|Bacteria	2|Bacteria	GM	domain, Protein	tonB5	-	2.7.11.1	ko:K03466,ko:K08884	-	-	-	-	ko00000,ko01000,ko01001,ko03036	3.A.12	-	-	Pkinase
NFNHFNFO_01604	33035.JPJF01000080_gene159	0.0	2854.0	COG4733@1|root,COG4733@2|Bacteria,1URCK@1239|Firmicutes,24CZ8@186801|Clostridia	186801|Clostridia	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,Peptidase_M60,fn3
NFNHFNFO_01605	33035.JPJF01000080_gene160	1.03e-247	682.0	COG1618@1|root,COG1763@1|root,COG1618@2|Bacteria,COG1763@2|Bacteria,1VGU5@1239|Firmicutes,24QRA@186801|Clostridia,3Y0TU@572511|Blautia	186801|Clostridia	F	NTPase	-	-	3.6.1.15	ko:K06928	ko00230,ko00730,ko01100,map00230,map00730,map01100	-	R00086,R00615	RC00002	ko00000,ko00001,ko01000	-	-	-	NTPase_1
NFNHFNFO_01607	33035.JPJF01000080_gene162	1.77e-265	732.0	COG0746@1|root,COG1524@1|root,COG0746@2|Bacteria,COG1524@2|Bacteria,1UQ1Y@1239|Firmicutes,257PR@186801|Clostridia,3Y0VI@572511|Blautia	186801|Clostridia	H	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_3
NFNHFNFO_01608	33035.JPJF01000080_gene163	5e-275	754.0	COG0303@1|root,COG0303@2|Bacteria,1TQJ8@1239|Firmicutes,248WP@186801|Clostridia,3Y0HF@572511|Blautia	186801|Clostridia	H	MoeA N-terminal region (domain I and II)	moeA	-	2.10.1.1	ko:K03750	ko00790,ko01100,map00790,map01100	-	R09735	RC03462	ko00000,ko00001,ko01000	-	-	-	MoCF_biosynth,MoeA_C,MoeA_N
NFNHFNFO_01609	33035.JPJF01000080_gene164	0.0	1830.0	COG3383@1|root,COG3383@2|Bacteria,1UI1F@1239|Firmicutes,25EAG@186801|Clostridia,3XYRD@572511|Blautia	186801|Clostridia	C	Molydopterin dinucleotide binding domain	fdhA2	-	1.17.1.11,1.17.1.9	ko:K00123,ko:K22341	ko00630,ko00680,ko01100,ko01120,ko01200,map00630,map00680,map01100,map01120,map01200	-	R00519	RC02796	ko00000,ko00001,ko01000	-	-	-	Fer2_4,Fer4,Fer4_6,Fer4_7,Molybdop_Fe4S4,Molybdopterin,Molydop_binding,NADH-G_4Fe-4S_3
NFNHFNFO_01610	33035.JPJF01000080_gene165	0.0	1229.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3XZ6P@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
NFNHFNFO_01611	33035.JPJF01000080_gene166	8.01e-112	321.0	COG1905@1|root,COG1905@2|Bacteria,1V4IR@1239|Firmicutes,25CD0@186801|Clostridia,3XZET@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
NFNHFNFO_01612	33035.JPJF01000080_gene167	9.99e-269	737.0	COG2208@1|root,COG2208@2|Bacteria,1TQUC@1239|Firmicutes,248FZ@186801|Clostridia,3XZWJ@572511|Blautia	186801|Clostridia	KT	Sigma factor PP2C-like phosphatases	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIE
NFNHFNFO_01613	33035.JPJF01000080_gene168	0.0	1073.0	COG2221@1|root,COG4624@1|root,COG2221@2|Bacteria,COG4624@2|Bacteria,1TRB4@1239|Firmicutes,25KD8@186801|Clostridia,3XYQ4@572511|Blautia	186801|Clostridia	C	PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	FeS,Fe_hyd_lg_C,Fer4,PAS
NFNHFNFO_01614	33035.JPJF01000080_gene169	1.63e-125	358.0	COG0398@1|root,COG0398@2|Bacteria,1V7NH@1239|Firmicutes,24HNU@186801|Clostridia,3Y1EU@572511|Blautia	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
NFNHFNFO_01615	33035.JPJF01000080_gene170	3.28e-252	692.0	COG0438@1|root,COG0438@2|Bacteria,1TPSS@1239|Firmicutes,249NS@186801|Clostridia,3Y0WU@572511|Blautia	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	ko:K13678	-	-	R10865	RC00005,RC00049	ko00000,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
NFNHFNFO_01616	33035.JPJF01000080_gene171	6.27e-273	750.0	COG0438@1|root,COG0438@2|Bacteria,1TPTA@1239|Firmicutes,24ANI@186801|Clostridia,3Y0H4@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	2.4.1.337	ko:K19002	ko00561,ko01100,map00561,map01100	-	R10850	RC00005,RC00059	ko00000,ko00001,ko01000,ko01003	-	GT4	-	Glyco_transf_4,Glycos_transf_1
NFNHFNFO_01617	476272.RUMHYD_02988	3.63e-46	168.0	2E2H9@1|root,32XM9@2|Bacteria,1VC5F@1239|Firmicutes,259ZF@186801|Clostridia,3XZVR@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF5067)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5067
NFNHFNFO_01619	33035.JPJF01000080_gene172	3.52e-154	436.0	2AYHW@1|root,31QMC@2|Bacteria,1V6S7@1239|Firmicutes,24NBV@186801|Clostridia,3Y013@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	TraX
NFNHFNFO_01620	33035.JPJF01000080_gene173	2.02e-122	351.0	COG1988@1|root,COG1988@2|Bacteria,1V742@1239|Firmicutes,24KF4@186801|Clostridia	186801|Clostridia	S	Membrane-bound metal-dependent hydrolase	-	-	-	ko:K07038	-	-	-	-	ko00000	-	-	-	YdjM
NFNHFNFO_01621	553973.CLOHYLEM_05457	7.77e-155	437.0	COG1266@1|root,COG1266@2|Bacteria,1VG77@1239|Firmicutes,250GM@186801|Clostridia	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	-	-	-	-	-	-	-	-	-	Abi
NFNHFNFO_01622	553973.CLOHYLEM_05456	8.76e-124	355.0	COG1309@1|root,COG1309@2|Bacteria,1V4GG@1239|Firmicutes,24DFV@186801|Clostridia,221IP@1506553|Lachnoclostridium	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_01623	33035.JPJF01000080_gene174	2.64e-126	363.0	COG1207@1|root,COG1207@2|Bacteria,1UH92@1239|Firmicutes,25PYU@186801|Clostridia,3XYPK@572511|Blautia	186801|Clostridia	M	UDP-N-acetylglucosamine diphosphorylase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep
NFNHFNFO_01624	33035.JPJF01000080_gene175	0.0	1258.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3XYKF@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	traI	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
NFNHFNFO_01625	33035.JPJF01000080_gene176	1.74e-267	733.0	COG0136@1|root,COG0136@2|Bacteria,1TPC6@1239|Firmicutes,248ZR@186801|Clostridia,3XZ7K@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	asd	-	1.2.1.11	ko:K00133	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R02291	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
NFNHFNFO_01626	33035.JPJF01000080_gene177	0.0	895.0	COG0165@1|root,COG0165@2|Bacteria,1TNZ6@1239|Firmicutes,2489H@186801|Clostridia,3XYGK@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argH	-	4.3.2.1	ko:K01755	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,map00220,map00250,map01100,map01110,map01130,map01230	M00029,M00844,M00845	R01086	RC00445,RC00447	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ASL_C2,Lyase_1
NFNHFNFO_01627	33035.JPJF01000080_gene178	3.25e-135	384.0	COG1636@1|root,COG1636@2|Bacteria,1TT7H@1239|Firmicutes,248EA@186801|Clostridia,3XYMA@572511|Blautia	186801|Clostridia	C	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)	queH	-	1.17.99.6	ko:K09765	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	DUF208
NFNHFNFO_01628	33035.JPJF01000080_gene179	2.3e-231	637.0	COG1052@1|root,COG1052@2|Bacteria,1TSZ6@1239|Firmicutes,249PP@186801|Clostridia,3XZ54@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	ldhA	-	1.1.1.28	ko:K03778	ko00620,ko01120,map00620,map01120	-	R00704	RC00044	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C,PTS-HPr
NFNHFNFO_01629	33035.JPJF01000080_gene180	1.55e-175	490.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,3XZ5T@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	ssuB_2	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NFNHFNFO_01630	33035.JPJF01000080_gene181	2.2e-159	450.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,3XZ84@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	ssuC_2	-	-	ko:K02050	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	BPD_transp_1
NFNHFNFO_01631	33035.JPJF01000080_gene182	2.4e-33	115.0	COG4877@1|root,COG4877@2|Bacteria,1VEY1@1239|Firmicutes,24MV0@186801|Clostridia,3Y0PD@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ParD_like,RHH_5
NFNHFNFO_01632	33035.JPJF01000080_gene183	5.28e-212	591.0	COG0330@1|root,COG0330@2|Bacteria,1TRN5@1239|Firmicutes,248UU@186801|Clostridia,3XYMI@572511|Blautia	186801|Clostridia	O	prohibitin homologues	-	-	-	-	-	-	-	-	-	-	-	-	Band_7
NFNHFNFO_01633	33035.JPJF01000080_gene184	3.94e-222	612.0	COG0441@1|root,COG0441@2|Bacteria,1TPW5@1239|Firmicutes,24B69@186801|Clostridia,3Y1G4@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01634	33035.JPJF01000080_gene185	1.25e-210	583.0	COG0719@1|root,COG0719@2|Bacteria,1TQ21@1239|Firmicutes,249IU@186801|Clostridia,3XYP6@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07033	-	-	-	-	ko00000	-	-	-	UPF0051
NFNHFNFO_01635	33035.JPJF01000080_gene186	1.81e-169	474.0	COG0396@1|root,COG0396@2|Bacteria,1TQ98@1239|Firmicutes,2489I@186801|Clostridia,3XZQE@572511|Blautia	186801|Clostridia	O	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K09013	-	-	-	-	ko00000,ko02000	-	-	-	ABC_tran
NFNHFNFO_01636	33035.JPJF01000080_gene187	1.37e-56	185.0	COG0790@1|root,COG0790@2|Bacteria,1TS5X@1239|Firmicutes,258E6@186801|Clostridia,3Y0MX@572511|Blautia	186801|Clostridia	S	Sel1-like repeats.	-	-	-	ko:K07126	-	-	-	-	ko00000	-	-	-	Sel1
NFNHFNFO_01637	33035.JPJF01000080_gene188	9.48e-303	824.0	COG0133@1|root,COG0133@2|Bacteria,1TPI3@1239|Firmicutes,24881@186801|Clostridia,3XYNP@572511|Blautia	186801|Clostridia	E	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine	trpB	-	4.2.1.20	ko:K01696,ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NFNHFNFO_01638	33035.JPJF01000080_gene189	1.85e-79	238.0	2E9W7@1|root,3341X@2|Bacteria,1VG1X@1239|Firmicutes,24RT9@186801|Clostridia,3Y1UX@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3887)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3887
NFNHFNFO_01639	33035.JPJF01000080_gene190	8.32e-233	650.0	COG3290@1|root,COG3290@2|Bacteria,1V225@1239|Firmicutes,24DB7@186801|Clostridia,3Y09H@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NFNHFNFO_01640	33035.JPJF01000080_gene191	1.8e-154	435.0	COG3279@1|root,COG3279@2|Bacteria,1V1GQ@1239|Firmicutes,24H3F@186801|Clostridia,3Y04V@572511|Blautia	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	ko:K02477	-	-	-	-	ko00000,ko02022	-	-	-	LytTR,Response_reg
NFNHFNFO_01641	33035.JPJF01000080_gene192	0.0	906.0	COG0714@1|root,COG0714@2|Bacteria,1U8NZ@1239|Firmicutes,248X1@186801|Clostridia,3XZAA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA,AAA_5
NFNHFNFO_01642	33035.JPJF01000080_gene193	1.54e-305	835.0	COG3864@1|root,COG3864@2|Bacteria,1TSI1@1239|Firmicutes,248YT@186801|Clostridia,3XZNV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF2201,DUF2201_N
NFNHFNFO_01643	33035.JPJF01000080_gene194	1.12e-151	432.0	2DMDS@1|root,32QT4@2|Bacteria,1VGZP@1239|Firmicutes,25EAH@186801|Clostridia,3Y07F@572511|Blautia	186801|Clostridia	S	Leucine rich repeats (6 copies)	-	-	-	-	-	-	-	-	-	-	-	-	LRR_5
NFNHFNFO_01644	33035.JPJF01000080_gene195	2.52e-129	368.0	COG2316@1|root,COG2316@2|Bacteria,1TSF7@1239|Firmicutes,24A1B@186801|Clostridia,3XZZD@572511|Blautia	186801|Clostridia	S	PFAM metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
NFNHFNFO_01645	33035.JPJF01000080_gene196	3.93e-236	650.0	COG0687@1|root,COG0687@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3XZJT@572511|Blautia	186801|Clostridia	P	Bacterial extracellular solute-binding protein	potD	-	-	ko:K11069,ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
NFNHFNFO_01646	33035.JPJF01000080_gene197	4.74e-175	489.0	COG1177@1|root,COG1177@2|Bacteria,1V0VD@1239|Firmicutes,25E3C@186801|Clostridia,3XZ3R@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K11070	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	iHN637.CLJU_RS10670	BPD_transp_1
NFNHFNFO_01647	33035.JPJF01000080_gene198	2.76e-188	525.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,24F3Z@186801|Clostridia,3XZMZ@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
NFNHFNFO_01648	33035.JPJF01000080_gene199	9.24e-250	688.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XZ16@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
NFNHFNFO_01650	33035.JPJF01000080_gene200	3.77e-88	259.0	COG4416@1|root,COG4416@2|Bacteria,1VEMD@1239|Firmicutes,24MRR@186801|Clostridia,3Y0F5@572511|Blautia	186801|Clostridia	S	COG NOG18757 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01651	33035.JPJF01000080_gene201	1.34e-115	332.0	COG0716@1|root,COG0716@2|Bacteria,1V7GG@1239|Firmicutes,24JSD@186801|Clostridia,3Y0FG@572511|Blautia	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_3
NFNHFNFO_01652	33035.JPJF01000080_gene202	1.97e-237	654.0	COG1902@1|root,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3XZ6J@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NFNHFNFO_01653	33035.JPJF01000080_gene203	5.82e-97	289.0	2DPSA@1|root,33365@2|Bacteria,1TTQC@1239|Firmicutes,258MF@186801|Clostridia,3Y0SE@572511|Blautia	186801|Clostridia	S	Sporulation and spore germination	-	-	-	-	-	-	-	-	-	-	-	-	Germane
NFNHFNFO_01654	33035.JPJF01000080_gene204	1.31e-191	534.0	COG0668@1|root,COG0668@2|Bacteria,1TR9Z@1239|Firmicutes,24CAG@186801|Clostridia,3XZH9@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	mscS	-	-	ko:K03442	-	-	-	-	ko00000,ko02000	1.A.23.2	-	-	MS_channel,TM_helix
NFNHFNFO_01655	33035.JPJF01000080_gene205	0.0	1560.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3XZ76@572511|Blautia	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NFNHFNFO_01656	33035.JPJF01000080_gene206	0.0	947.0	COG0516@1|root,COG0517@1|root,COG0516@2|Bacteria,COG0517@2|Bacteria,1TNZ1@1239|Firmicutes,247PS@186801|Clostridia,3XZR0@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth	guaB	-	1.1.1.205	ko:K00088	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	M00050	R01130,R08240	RC00143,RC02207	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	CBS,IMPDH
NFNHFNFO_01657	768710.DesyoDRAFT_3743	6.35e-24	98.2	COG1846@1|root,COG1846@2|Bacteria,1VBPQ@1239|Firmicutes,25CVG@186801|Clostridia,265Y7@186807|Peptococcaceae	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
NFNHFNFO_01658	1123311.KB904455_gene410	4.7e-51	169.0	COG0716@1|root,COG0716@2|Bacteria,1VFBC@1239|Firmicutes,4ITQ7@91061|Bacilli	91061|Bacilli	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_5
NFNHFNFO_01659	642492.Clole_4203	4.86e-49	165.0	COG1309@1|root,COG1309@2|Bacteria,1V1ZJ@1239|Firmicutes,24FQ3@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, tetr family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_01660	33035.JPJF01000080_gene209	5.64e-112	321.0	COG1905@1|root,COG1905@2|Bacteria,1V4IR@1239|Firmicutes,25CD0@186801|Clostridia,3XZET@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00334	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx
NFNHFNFO_01661	33035.JPJF01000080_gene210	0.0	1214.0	COG1894@1|root,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3XZ6P@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.6.5.3	ko:K00335	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Complex1_51K,Fer4,NADH_4Fe-4S,SLBB
NFNHFNFO_01662	33035.JPJF01000080_gene211	0.0	1134.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,3XYQE@572511|Blautia	186801|Clostridia	C	NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	-	-	1.12.1.3,1.6.5.3	ko:K00336,ko:K18332	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	2Fe-2S_thioredx,Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_6,Fer4_7,NADH-G_4Fe-4S_3
NFNHFNFO_01663	33035.JPJF01000080_gene213	3.57e-94	276.0	COG0454@1|root,COG0456@2|Bacteria,1V6D6@1239|Firmicutes,24KC1@186801|Clostridia	186801|Clostridia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_01664	33035.JPJF01000080_gene214	1.12e-267	734.0	COG0486@1|root,COG0486@2|Bacteria,1TQA8@1239|Firmicutes,247M4@186801|Clostridia,3XZ1Y@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	hydF	-	-	-	-	-	-	-	-	-	-	-	MMR_HSR1
NFNHFNFO_01665	33035.JPJF01000080_gene215	0.0	936.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,3XYRP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	hydG	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
NFNHFNFO_01666	33035.JPJF01000080_gene216	4.51e-239	659.0	COG0502@1|root,COG0502@2|Bacteria,1TPYQ@1239|Firmicutes,248H8@186801|Clostridia,3XZNK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	hydE	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	Radical_SAM
NFNHFNFO_01667	33035.JPJF01000080_gene217	4.09e-290	793.0	COG4198@1|root,COG4198@2|Bacteria,1TQSW@1239|Firmicutes,249E4@186801|Clostridia,3XZ64@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1015)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1015
NFNHFNFO_01669	33035.JPJF01000080_gene218	9.79e-279	762.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,248H9@186801|Clostridia,3XYS5@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pdxB	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NFNHFNFO_01670	33035.JPJF01000080_gene219	1.18e-254	699.0	COG1932@1|root,COG1932@2|Bacteria,1TP6Y@1239|Firmicutes,247SM@186801|Clostridia,3XZDW@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine	serC	-	2.6.1.52	ko:K00831	ko00260,ko00680,ko00750,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map00750,map01100,map01120,map01130,map01200,map01230	M00020,M00124	R04173,R05085	RC00006,RC00036	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_5
NFNHFNFO_01671	33035.JPJF01000080_gene220	0.0	1058.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3XYQS@572511|Blautia	186801|Clostridia	H	acetolactate synthase large subunit	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NFNHFNFO_01672	33035.JPJF01000080_gene221	0.0	1079.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3XYR1@572511|Blautia	186801|Clostridia	H	Belongs to the IlvD Edd family	ilvD	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
NFNHFNFO_01673	33035.JPJF01000080_gene222	8.93e-250	686.0	COG0473@1|root,COG0473@2|Bacteria,1TPEM@1239|Firmicutes,24A63@186801|Clostridia,3XZ5D@572511|Blautia	186801|Clostridia	C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate	leuB	-	1.1.1.85	ko:K00052	ko00290,ko00660,ko01100,ko01110,ko01210,ko01230,map00290,map00660,map01100,map01110,map01210,map01230	M00432,M00535	R00994,R04426,R10052	RC00084,RC00417,RC03036	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Iso_dh
NFNHFNFO_01675	33035.JPJF01000025_gene2613	7.51e-23	87.8	2CJ2I@1|root,33JSU@2|Bacteria,1VPQS@1239|Firmicutes,24VAW@186801|Clostridia,3Y277@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01676	33035.JPJF01000025_gene2614	0.0	1137.0	COG3383@1|root,COG4624@1|root,COG3383@2|Bacteria,COG4624@2|Bacteria,1TP6C@1239|Firmicutes,24897@186801|Clostridia,3XYQE@572511|Blautia	186801|Clostridia	C	NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G)	hydC	-	1.6.5.3	ko:K00336	ko00190,ko01100,map00190,map01100	M00144	R11945	RC00061	ko00000,ko00001,ko00002,ko01000	3.D.1	-	-	Fe_hyd_SSU,Fe_hyd_lg_C,Fer2_4,Fer4,Fer4_7,NADH-G_4Fe-4S_3
NFNHFNFO_01677	33035.JPJF01000025_gene2615	0.0	1177.0	COG0493@1|root,COG1894@1|root,COG0493@2|Bacteria,COG1894@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3XZ32@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	sfrB	-	1.17.1.10	ko:K15022	ko00680,ko00720,ko01120,ko01200,map00680,map00720,map01120,map01200	M00377	R00134	RC02796	ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_20,NADH_4Fe-4S,Pyr_redox_2
NFNHFNFO_01678	33035.JPJF01000025_gene2616	5.58e-194	538.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1V8XZ@1239|Firmicutes,24DFZ@186801|Clostridia	186801|Clostridia	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
NFNHFNFO_01679	33035.JPJF01000025_gene2617	4.68e-183	512.0	COG1760@1|root,COG1760@2|Bacteria,1TP79@1239|Firmicutes,2480J@186801|Clostridia,3XYU6@572511|Blautia	186801|Clostridia	E	L-serine dehydratase, iron-sulfur-dependent, alpha subunit	sdaAA	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	SDH_alpha
NFNHFNFO_01680	33035.JPJF01000025_gene2618	5.41e-150	422.0	COG1760@1|root,COG1760@2|Bacteria,1U8TZ@1239|Firmicutes,24AEE@186801|Clostridia,3XZ6R@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	sdaAB	-	4.3.1.17	ko:K01752	ko00260,ko00270,ko01100,ko01110,ko01130,ko01200,ko01230,map00260,map00270,map01100,map01110,map01130,map01200,map01230	-	R00220,R00590	RC00331,RC02600	ko00000,ko00001,ko01000	-	-	-	ACT,SDH_beta
NFNHFNFO_01681	33035.JPJF01000025_gene2619	2.33e-68	207.0	COG1862@1|root,COG1862@2|Bacteria,1VEMC@1239|Firmicutes,24MMT@186801|Clostridia,3Y0GK@572511|Blautia	186801|Clostridia	U	COG COG1862 Preprotein translocase subunit YajC	yajC	-	-	ko:K03210	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	YajC
NFNHFNFO_01682	33035.JPJF01000025_gene2620	1.19e-279	763.0	COG0343@1|root,COG0343@2|Bacteria,1TNZ4@1239|Firmicutes,247NJ@186801|Clostridia,3XZ2I@572511|Blautia	186801|Clostridia	F	Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine)	tgt	-	2.4.2.29	ko:K00773	-	-	R03789,R10209	RC00063	ko00000,ko01000,ko03016	-	-	-	TGT
NFNHFNFO_01683	33035.JPJF01000025_gene2621	0.0	2753.0	COG1924@1|root,COG3580@1|root,COG3581@1|root,COG1924@2|Bacteria,COG3580@2|Bacteria,COG3581@2|Bacteria,1TPU5@1239|Firmicutes,2481F@186801|Clostridia,3XYXK@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	hgdC2	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG,DUF2229,HGD-D
NFNHFNFO_01684	33035.JPJF01000025_gene2622	0.0	955.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,3XZ3N@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	spoVB1	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
NFNHFNFO_01685	33035.JPJF01000025_gene2623	3.87e-169	471.0	COG0692@1|root,COG0692@2|Bacteria,1TPSN@1239|Firmicutes,247N9@186801|Clostridia,3XYSN@572511|Blautia	186801|Clostridia	L	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine	ung	-	3.2.2.27	ko:K03648	ko03410,ko05340,map03410,map05340	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
NFNHFNFO_01686	33035.JPJF01000025_gene2624	0.0	917.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XZCX@572511|Blautia	186801|Clostridia	T	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NFNHFNFO_01687	33035.JPJF01000025_gene2625	1.06e-157	442.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia,3XZ4H@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_6	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_01688	33035.JPJF01000025_gene2626	5.15e-130	375.0	COG4395@1|root,COG4395@2|Bacteria,1V9GZ@1239|Firmicutes,24HB5@186801|Clostridia,3Y1KI@572511|Blautia	186801|Clostridia	S	Tim44	-	-	-	-	-	-	-	-	-	-	-	-	Tim44
NFNHFNFO_01690	33035.JPJF01000025_gene2627	5.94e-71	213.0	COG2201@1|root,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	-	-	3.1.1.61,3.5.1.44	ko:K02282,ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko02044	-	-	-	CheB_methylest,Response_reg,Spo0A_C
NFNHFNFO_01692	33035.JPJF01000025_gene2629	1.88e-145	411.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,2484X@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_01693	33035.JPJF01000025_gene2630	5.8e-187	526.0	COG0642@1|root,COG5002@1|root,COG2205@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NFNHFNFO_01694	411468.CLOSCI_00082	4.64e-18	75.9	2EKZT@1|root,30FK0@2|Bacteria,1UE5V@1239|Firmicutes,25J0U@186801|Clostridia,223KH@1506553|Lachnoclostridium	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01695	33035.JPJF01000025_gene2632	5.28e-166	468.0	COG1131@1|root,COG1131@2|Bacteria,1TQIH@1239|Firmicutes,248WG@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K01990,ko:K16907	ko02010,map02010	M00224,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_01696	33035.JPJF01000025_gene2633	4.79e-170	482.0	COG0842@1|root,COG0842@2|Bacteria,1TQ6H@1239|Firmicutes,24A0U@186801|Clostridia	186801|Clostridia	V	Transport permease protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_3
NFNHFNFO_01697	33035.JPJF01000025_gene2634	2.58e-153	440.0	COG0842@1|root,COG0842@2|Bacteria,1TPJM@1239|Firmicutes,24BZX@186801|Clostridia	186801|Clostridia	V	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
NFNHFNFO_01698	33035.JPJF01000025_gene2635	0.0	1033.0	COG1164@1|root,COG1164@2|Bacteria,1TPV4@1239|Firmicutes,2495D@186801|Clostridia,3XZPT@572511|Blautia	186801|Clostridia	E	oligoendopeptidase, M3 family	pz-A	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M3
NFNHFNFO_01699	33035.JPJF01000025_gene2636	2.06e-103	299.0	COG0691@1|root,COG0691@2|Bacteria,1V3IJ@1239|Firmicutes,24HD6@186801|Clostridia,3XZU0@572511|Blautia	186801|Clostridia	O	the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA	smpB	-	-	ko:K03664	-	-	-	-	ko00000	-	-	-	SmpB
NFNHFNFO_01700	33035.JPJF01000025_gene2637	0.0	1355.0	COG0557@1|root,COG0557@2|Bacteria,1TQ1G@1239|Firmicutes,247ZS@186801|Clostridia,3XZBT@572511|Blautia	186801|Clostridia	K	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs	rnr	-	-	ko:K12573	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	OB_RNB,RNB,S1
NFNHFNFO_01701	537007.BLAHAN_05226	5.26e-36	123.0	COG1314@1|root,COG1314@2|Bacteria,1VG46@1239|Firmicutes,25N7Q@186801|Clostridia,3Y0K4@572511|Blautia	186801|Clostridia	U	Preprotein translocase SecG subunit	secG	-	-	ko:K03075	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.2	-	-	SecG
NFNHFNFO_01702	33035.JPJF01000025_gene2639	3.95e-309	843.0	COG0148@1|root,COG0148@2|Bacteria,1TP2S@1239|Firmicutes,247TU@186801|Clostridia,3XYIB@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis	eno	-	4.2.1.11	ko:K01689	ko00010,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko03018,ko04066,map00010,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map03018,map04066	M00001,M00002,M00003,M00346,M00394	R00658	RC00349	ko00000,ko00001,ko00002,ko01000,ko03019,ko04147	-	-	-	Enolase_C,Enolase_N
NFNHFNFO_01703	33035.JPJF01000025_gene2640	2.1e-151	427.0	2CN13@1|root,32SG0@2|Bacteria,1VBIH@1239|Firmicutes,24Q0G@186801|Clostridia,3Y1YK@572511|Blautia	186801|Clostridia	S	Camelysin metallo-endopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M73
NFNHFNFO_01704	33035.JPJF01000025_gene2641	2.85e-93	275.0	COG0681@1|root,COG0681@2|Bacteria,1VH82@1239|Firmicutes,259N9@186801|Clostridia,3Y23E@572511|Blautia	186801|Clostridia	U	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
NFNHFNFO_01705	33035.JPJF01000025_gene2642	5.67e-130	372.0	2BJ2J@1|root,32DB9@2|Bacteria,1TUKD@1239|Firmicutes,25J0I@186801|Clostridia,3Y24I@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01706	33035.JPJF01000025_gene2643	9.52e-107	311.0	2B21K@1|root,31UIF@2|Bacteria,1TUKE@1239|Firmicutes,25PUX@186801|Clostridia,3Y214@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01707	33035.JPJF01000025_gene2644	0.0	1199.0	COG3087@1|root,COG4932@1|root,COG3087@2|Bacteria,COG4932@2|Bacteria,1VDGY@1239|Firmicutes,253AP@186801|Clostridia	186801|Clostridia	M	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01708	33035.JPJF01000025_gene2645	0.0	871.0	COG0407@1|root,COG0407@2|Bacteria,1TSSK@1239|Firmicutes,24CHA@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_01709	33035.JPJF01000025_gene2646	4.51e-192	534.0	COG4977@1|root,COG4977@2|Bacteria,1V5CN@1239|Firmicutes,25E9D@186801|Clostridia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_01710	33035.JPJF01000025_gene2647	0.0	981.0	COG0696@1|root,COG0696@2|Bacteria,1TPM4@1239|Firmicutes,247JG@186801|Clostridia,3XZ21@572511|Blautia	186801|Clostridia	G	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate	gpmI	-	5.4.2.12	ko:K15633	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,Phosphodiest,iPGM_N
NFNHFNFO_01711	33035.JPJF01000025_gene2648	4.09e-166	465.0	COG1126@1|root,COG1126@2|Bacteria,1TNYD@1239|Firmicutes,247QZ@186801|Clostridia,3XZ1I@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	glnQ	-	3.6.3.21	ko:K02028	-	M00236	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.3	-	-	ABC_tran
NFNHFNFO_01712	33035.JPJF01000025_gene2649	7.45e-118	341.0	COG0765@1|root,COG0765@2|Bacteria,1TPM3@1239|Firmicutes,248UY@186801|Clostridia,3XZT5@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	ArtM	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	BPD_transp_1,SBP_bac_3
NFNHFNFO_01713	33035.JPJF01000025_gene2650	1.04e-170	478.0	COG0834@1|root,COG0834@2|Bacteria,1TT16@1239|Firmicutes,24CEZ@186801|Clostridia,3XYTF@572511|Blautia	186801|Clostridia	ET	COG COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain	artP	-	-	ko:K02029,ko:K02030	-	M00236	-	-	ko00000,ko00002,ko02000	3.A.1.3	-	-	SBP_bac_3
NFNHFNFO_01714	33035.JPJF01000025_gene2651	5.04e-311	852.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3Y14Z@572511|Blautia	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NFNHFNFO_01715	33035.JPJF01000025_gene2652	8.3e-206	570.0	COG1313@1|root,COG1313@2|Bacteria,1TRUV@1239|Firmicutes,247VW@186801|Clostridia,3XZB3@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	PflX	-	1.97.1.4	ko:K04070	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NFNHFNFO_01716	33035.JPJF01000025_gene2653	1.05e-174	487.0	COG0149@1|root,COG0149@2|Bacteria,1TP2F@1239|Firmicutes,248JN@186801|Clostridia,3XYGS@572511|Blautia	186801|Clostridia	G	Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P)	tpiA	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	iHN637.CLJU_RS19265	TIM
NFNHFNFO_01717	33035.JPJF01000025_gene2654	3.31e-282	771.0	COG0126@1|root,COG0126@2|Bacteria,1TP3H@1239|Firmicutes,248VS@186801|Clostridia,3XYK6@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score	pgk	-	2.7.2.3,5.3.1.1	ko:K00927,ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01015,R01512	RC00002,RC00043,RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGK
NFNHFNFO_01718	33035.JPJF01000025_gene2655	7.48e-239	657.0	COG0057@1|root,COG0057@2|Bacteria,1TNYU@1239|Firmicutes,247IZ@186801|Clostridia,3XZGK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	gap	-	1.2.1.12	ko:K00134	ko00010,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04066,ko05010,map00010,map00710,map01100,map01110,map01120,map01130,map01200,map01230,map04066,map05010	M00001,M00002,M00003,M00165,M00166,M00308,M00552	R01061	RC00149	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	Gp_dh_C,Gp_dh_N
NFNHFNFO_01719	33035.JPJF01000025_gene2656	1.57e-189	526.0	COG1387@1|root,COG1387@2|Bacteria,1TRKS@1239|Firmicutes,249TM@186801|Clostridia,3XZF9@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisK	-	3.1.3.15	ko:K04486	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03013	RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PHP
NFNHFNFO_01720	33035.JPJF01000025_gene2657	8.24e-40	137.0	COG0454@1|root,COG0456@2|Bacteria,1VBWD@1239|Firmicutes,24NNB@186801|Clostridia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
NFNHFNFO_01721	33035.JPJF01000025_gene2657	1.05e-48	160.0	COG0454@1|root,COG0456@2|Bacteria,1VBWD@1239|Firmicutes,24NNB@186801|Clostridia	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_7
NFNHFNFO_01722	33035.JPJF01000025_gene2658	1.32e-250	688.0	COG0482@1|root,COG0482@2|Bacteria,1TPIZ@1239|Firmicutes,247YV@186801|Clostridia,3XZBE@572511|Blautia	186801|Clostridia	J	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34	mnmA	-	2.8.1.13	ko:K00566	ko04122,map04122	-	R08700	RC02313,RC02315	ko00000,ko00001,ko01000,ko03016	-	-	-	tRNA_Me_trans
NFNHFNFO_01723	33035.JPJF01000025_gene2659	7.07e-97	282.0	COG0822@1|root,COG0822@2|Bacteria,1V3H9@1239|Firmicutes,24HDD@186801|Clostridia,3XZVP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	nifU	-	-	ko:K04488	-	-	-	-	ko00000	-	-	-	NifU_N
NFNHFNFO_01724	33035.JPJF01000025_gene2660	9.31e-273	748.0	COG1104@1|root,COG1104@2|Bacteria,1TP21@1239|Firmicutes,24888@186801|Clostridia,3XZ67@572511|Blautia	186801|Clostridia	E	Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins	iscS	-	2.8.1.7	ko:K04487	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07460,R11528,R11529	RC01789,RC02313	ko00000,ko00001,ko01000,ko02048,ko03016,ko03029	-	-	-	Aminotran_5
NFNHFNFO_01725	33035.JPJF01000025_gene2661	2.68e-97	284.0	COG1959@1|root,COG1959@2|Bacteria,1V3QB@1239|Firmicutes,24JIV@186801|Clostridia,3Y0AW@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	iscR	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NFNHFNFO_01726	33035.JPJF01000025_gene2662	5.78e-304	830.0	COG2244@1|root,COG2244@2|Bacteria,1TNYX@1239|Firmicutes,2485G@186801|Clostridia,3XZ1Z@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	spoVB	-	-	ko:K06409	-	-	-	-	ko00000,ko02000	2.A.66.2.14	-	-	Polysacc_synt,Polysacc_synt_C
NFNHFNFO_01727	33035.JPJF01000025_gene2663	9.67e-250	685.0	COG0722@1|root,COG0722@2|Bacteria,1TQI4@1239|Firmicutes,24842@186801|Clostridia,3XYX3@572511|Blautia	186801|Clostridia	E	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)	aroH	-	2.5.1.54	ko:K01626	ko00400,ko01100,ko01110,ko01130,ko01230,ko02024,map00400,map01100,map01110,map01130,map01230,map02024	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS07240	DAHP_synth_1
NFNHFNFO_01728	33035.JPJF01000025_gene2664	9.48e-205	567.0	COG4974@1|root,COG4974@2|Bacteria,1TQRG@1239|Firmicutes,247QQ@186801|Clostridia,3XZAM@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	xerC	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_integrase
NFNHFNFO_01729	537007.BLAHAN_05205	1.24e-45	155.0	2EKG7@1|root,33E68@2|Bacteria,1VYC7@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	SpoIIM
NFNHFNFO_01730	33035.JPJF01000025_gene2666	0.0	913.0	COG1418@1|root,COG1418@2|Bacteria,1TP48@1239|Firmicutes,248G8@186801|Clostridia,3XZ66@572511|Blautia	186801|Clostridia	S	Endoribonuclease that initiates mRNA decay	rny	-	-	ko:K18682	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	DUF3552,HD,KH_1
NFNHFNFO_01731	33035.JPJF01000025_gene2667	2.02e-122	351.0	COG2137@1|root,COG2137@2|Bacteria,1V72V@1239|Firmicutes,24J7X@186801|Clostridia,3Y0I4@572511|Blautia	186801|Clostridia	S	Regulatory protein RecX	recX	-	-	ko:K03565	-	-	-	-	ko00000,ko03400	-	-	-	RecX
NFNHFNFO_01732	33035.JPJF01000025_gene2668	9.36e-227	630.0	COG0468@1|root,COG0468@2|Bacteria,1TPD5@1239|Firmicutes,247SF@186801|Clostridia,3XZ9Q@572511|Blautia	186801|Clostridia	L	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage	recA	-	-	ko:K03553	ko03440,map03440	M00729	-	-	ko00000,ko00001,ko00002,ko03400	-	-	-	RecA
NFNHFNFO_01733	33035.JPJF01000025_gene2669	3.11e-47	152.0	COG5577@1|root,COG5577@2|Bacteria,1VGMH@1239|Firmicutes,24QT7@186801|Clostridia,3Y0E8@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Coat_F
NFNHFNFO_01734	33035.JPJF01000025_gene2670	8.73e-32	111.0	2E6Q9@1|root,331AH@2|Bacteria,1VETD@1239|Firmicutes,24REB@186801|Clostridia,3Y0QY@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score 8.82	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01735	33035.JPJF01000025_gene2671	0.0	1133.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,3Y18J@572511|Blautia	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NFNHFNFO_01736	33035.JPJF01000025_gene2672	5.01e-172	481.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,3XZDV@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	bceA	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_01737	33035.JPJF01000025_gene2673	0.0	1154.0	COG3808@1|root,COG3808@2|Bacteria,1TNZI@1239|Firmicutes,248KS@186801|Clostridia,3XZQ4@572511|Blautia	186801|Clostridia	C	Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane	hppA	-	3.6.1.1	ko:K15987	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	3.A.10.1	-	-	H_PPase
NFNHFNFO_01738	33035.JPJF01000026_gene2675	0.0	1414.0	COG0446@1|root,COG0607@1|root,COG2210@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,COG2210@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,3XZ97@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 9.98	cdr	-	-	-	-	-	-	-	-	-	-	-	DrsE_2,Pyr_redox_2,Pyr_redox_dim,Rhodanese,TusA
NFNHFNFO_01739	33035.JPJF01000026_gene2676	1.01e-212	591.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,3Y000@572511|Blautia	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
NFNHFNFO_01740	33035.JPJF01000026_gene2677	1.9e-141	402.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_01741	33035.JPJF01000026_gene2678	0.0	972.0	COG0297@1|root,COG0297@2|Bacteria,1TQ4M@1239|Firmicutes,248G1@186801|Clostridia,3XYMY@572511|Blautia	186801|Clostridia	G	Synthesizes alpha-1,4-glucan chains using ADP-glucose	glgA	-	2.4.1.21	ko:K00703	ko00500,ko01100,ko01110,ko02026,map00500,map01100,map01110,map02026	M00565	R02421	RC00005	ko00000,ko00001,ko00002,ko01000,ko01003	-	GT5	-	Glyco_transf_5,Glycos_transf_1
NFNHFNFO_01742	33035.JPJF01000026_gene2679	1.96e-182	508.0	COG2201@1|root,COG2201@2|Bacteria,1VQS3@1239|Firmicutes,25E3X@186801|Clostridia,3XYUD@572511|Blautia	186801|Clostridia	NT	May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process	spo0A	-	-	ko:K03413,ko:K07699	ko02020,ko02024,ko02030,map02020,map02024,map02030	M00485,M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg,Spo0A_C
NFNHFNFO_01743	33035.JPJF01000026_gene2680	4.67e-264	725.0	COG3480@1|root,COG3480@2|Bacteria,1UI0S@1239|Firmicutes,25E9E@186801|Clostridia,3XZ8A@572511|Blautia	186801|Clostridia	T	stage IV sporulation protein B	spoIVB	-	3.4.21.116	ko:K06399	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	PDZ_2,Peptidase_S55
NFNHFNFO_01744	33035.JPJF01000026_gene2681	0.0	990.0	COG0497@1|root,COG0497@2|Bacteria,1TP99@1239|Firmicutes,247KB@186801|Clostridia,3XZKD@572511|Blautia	186801|Clostridia	L	May be involved in recombinational repair of damaged DNA	recN	-	-	ko:K03631	-	-	-	-	ko00000,ko03400	-	-	-	AAA_23,SMC_N
NFNHFNFO_01745	33035.JPJF01000026_gene2682	9.03e-103	298.0	COG1438@1|root,COG1438@2|Bacteria,1V1R7@1239|Firmicutes,24HGQ@186801|Clostridia,3Y063@572511|Blautia	186801|Clostridia	K	Regulates arginine biosynthesis genes	argR	-	-	ko:K03402	-	-	-	-	ko00000,ko03000	-	-	-	Arg_repressor,Arg_repressor_C
NFNHFNFO_01746	33035.JPJF01000026_gene2683	3.69e-198	550.0	COG0061@1|root,COG0061@2|Bacteria,1TRB3@1239|Firmicutes,24BG6@186801|Clostridia,3XZAI@572511|Blautia	186801|Clostridia	H	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP	nadK	-	2.7.1.23	ko:K00858	ko00760,ko01100,map00760,map01100	-	R00104	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS05480	NAD_kinase
NFNHFNFO_01747	33035.JPJF01000026_gene2684	5.82e-182	507.0	COG1189@1|root,COG1189@2|Bacteria,1TPE4@1239|Firmicutes,247VH@186801|Clostridia,3XZ0P@572511|Blautia	186801|Clostridia	J	ribosomal RNA large subunit methyltransferase J	rrmJ	-	2.1.1.226,2.1.1.227	ko:K06442	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	FtsJ,S4
NFNHFNFO_01748	33035.JPJF01000026_gene2685	0.0	1175.0	COG1154@1|root,COG1154@2|Bacteria,1TP37@1239|Firmicutes,247P1@186801|Clostridia,3XYQF@572511|Blautia	186801|Clostridia	H	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)	dxs	-	2.2.1.7	ko:K01662	ko00730,ko00900,ko01100,ko01110,ko01130,map00730,map00900,map01100,map01110,map01130	M00096	R05636	RC00032	ko00000,ko00001,ko00002,ko01000	-	-	-	DXP_synthase_N,Transket_pyr,Transketolase_C
NFNHFNFO_01749	33035.JPJF01000026_gene2686	4.7e-187	522.0	COG0142@1|root,COG0142@2|Bacteria,1TPQY@1239|Firmicutes,248DE@186801|Clostridia,3XZAH@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 9.98	ispA	-	2.5.1.1,2.5.1.10,2.5.1.29	ko:K13789	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00364,M00366	R01658,R02003,R02061	RC00279	ko00000,ko00001,ko00002,ko01000,ko01006	-	-	iHN637.CLJU_RS05465	polyprenyl_synt
NFNHFNFO_01750	33035.JPJF01000026_gene2687	4.68e-39	130.0	COG1722@1|root,COG1722@2|Bacteria,1VK9I@1239|Firmicutes,24UH5@186801|Clostridia,3Y0QF@572511|Blautia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseB	-	3.1.11.6	ko:K03602	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_S
NFNHFNFO_01751	33035.JPJF01000026_gene2688	4.06e-238	661.0	COG1570@1|root,COG1570@2|Bacteria,1TP4E@1239|Firmicutes,247KE@186801|Clostridia,3XZS9@572511|Blautia	186801|Clostridia	L	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides	xseA	-	3.1.11.6	ko:K03601	ko03430,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exonuc_VII_L,tRNA_anti_2
NFNHFNFO_01752	33035.JPJF01000026_gene2689	2.69e-77	231.0	COG0781@1|root,COG0781@2|Bacteria,1VA9B@1239|Firmicutes,24MQ3@186801|Clostridia,3Y08R@572511|Blautia	186801|Clostridia	K	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons	nusB	-	-	ko:K03625	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	NusB
NFNHFNFO_01753	33035.JPJF01000026_gene2690	7.21e-81	240.0	COG1302@1|root,COG1302@2|Bacteria,1V4IC@1239|Firmicutes,24JNM@186801|Clostridia,3Y075@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	asp	-	-	-	-	-	-	-	-	-	-	-	Asp23
NFNHFNFO_01754	33035.JPJF01000026_gene2691	0.0	1499.0	COG0493@1|root,COG1902@1|root,COG0493@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3Y1FD@572511|Blautia	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NFNHFNFO_01755	33035.JPJF01000026_gene2692	1.34e-146	415.0	COG1614@1|root,COG1614@2|Bacteria,1V37P@1239|Firmicutes,24KHT@186801|Clostridia,3Y1QJ@572511|Blautia	186801|Clostridia	C	CO dehydrogenase/acetyl-CoA synthase complex beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	CdhC
NFNHFNFO_01757	33035.JPJF01000026_gene2694	1.88e-180	503.0	COG1924@1|root,COG1924@2|Bacteria,1TQSD@1239|Firmicutes,2481W@186801|Clostridia,3Y04S@572511|Blautia	186801|Clostridia	I	BadF/BadG/BcrA/BcrD ATPase family	-	-	-	-	-	-	-	-	-	-	-	-	BcrAD_BadFG
NFNHFNFO_01758	33035.JPJF01000026_gene2695	0.0	1105.0	COG1775@1|root,COG1775@2|Bacteria,1TS7H@1239|Firmicutes,2493U@186801|Clostridia,3Y0V9@572511|Blautia	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
NFNHFNFO_01759	33035.JPJF01000026_gene2696	2.84e-279	764.0	COG1775@1|root,COG1775@2|Bacteria,1TPEF@1239|Firmicutes,24A11@186801|Clostridia,3Y0XX@572511|Blautia	186801|Clostridia	E	2-hydroxyglutaryl-CoA dehydratase, D-component	-	-	-	-	-	-	-	-	-	-	-	-	HGD-D
NFNHFNFO_01760	33035.JPJF01000026_gene2697	1.92e-163	459.0	COG3640@1|root,COG3640@2|Bacteria,1UZHR@1239|Firmicutes,24BYR@186801|Clostridia,3XYW4@572511|Blautia	186801|Clostridia	D	Anion-transporting ATPase	-	-	-	ko:K07321	-	-	-	-	ko00000	-	-	-	AAA_31,CbiA
NFNHFNFO_01761	33035.JPJF01000026_gene2698	3.67e-120	343.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia,3Y0DK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
NFNHFNFO_01762	33035.JPJF01000026_gene2699	0.0	1030.0	COG4108@1|root,COG4108@2|Bacteria,1TPYT@1239|Firmicutes,247X3@186801|Clostridia,3XZKH@572511|Blautia	186801|Clostridia	J	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP	prfC	-	-	ko:K02837	-	-	-	-	ko00000,ko03012	-	-	-	GTP_EFTU,GTP_EFTU_D2,RF3_C
NFNHFNFO_01763	33035.JPJF01000026_gene2700	1.4e-132	382.0	2E3US@1|root,32YS3@2|Bacteria,1VESK@1239|Firmicutes,24R9H@186801|Clostridia,3Y02H@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	spoIIIAH	-	-	ko:K06397	-	-	-	-	ko00000	1.A.34.1.1	-	-	SpoIIIAH
NFNHFNFO_01764	33035.JPJF01000026_gene2701	1.62e-87	259.0	2E6BB@1|root,330Z5@2|Bacteria,1VF3M@1239|Firmicutes,24RAX@186801|Clostridia,3Y0J8@572511|Blautia	186801|Clostridia	S	COG NOG11553 non supervised orthologous group	spoIIIAG	-	-	ko:K06396	-	-	-	-	ko00000	-	-	-	-
NFNHFNFO_01765	33035.JPJF01000026_gene2702	7.12e-68	206.0	2E7KE@1|root,3322G@2|Bacteria,1VKPT@1239|Firmicutes,24SKX@186801|Clostridia,3Y0SD@572511|Blautia	186801|Clostridia	S	COG NOG13844 non supervised orthologous group	-	-	-	ko:K06395	-	-	-	-	ko00000	-	-	-	Spore_III_AF
NFNHFNFO_01766	33035.JPJF01000026_gene2703	1.49e-235	660.0	2C2CG@1|root,2Z7PW@2|Bacteria,1TQQ2@1239|Firmicutes,24AH2@186801|Clostridia,3XYI3@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spoIIIAE	-	-	ko:K06394	-	-	-	-	ko00000	-	-	-	Spore_III_AE
NFNHFNFO_01767	33035.JPJF01000026_gene2704	2.8e-79	236.0	2CPUI@1|root,32SJW@2|Bacteria,1VA9Y@1239|Firmicutes,24NK6@186801|Clostridia,3Y0FF@572511|Blautia	186801|Clostridia	S	COG NOG13205 non supervised orthologous group	spoIIIAD	-	-	ko:K06393	-	-	-	-	ko00000	-	-	-	SpoIIIAC
NFNHFNFO_01768	33035.JPJF01000026_gene2705	1.35e-34	118.0	2E555@1|root,32ZY3@2|Bacteria,1VEM4@1239|Firmicutes,24QNR@186801|Clostridia,3Y0M5@572511|Blautia	186801|Clostridia	S	COG NOG17863 non supervised orthologous group	spoIIIAC	-	-	ko:K06392	-	-	-	-	ko00000	-	-	-	SpoIIIAC
NFNHFNFO_01769	33035.JPJF01000026_gene2706	5.2e-103	300.0	2CEWW@1|root,3181X@2|Bacteria,1U7IP@1239|Firmicutes,2590I@186801|Clostridia,3Y0MY@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06391	-	-	-	-	ko00000	-	-	-	Spore_III_AB
NFNHFNFO_01770	33035.JPJF01000026_gene2707	3.83e-230	634.0	COG3854@1|root,COG3854@2|Bacteria,1TQ23@1239|Firmicutes,248S2@186801|Clostridia,3XYN0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	spoIIIAA	-	-	ko:K06390	-	-	-	-	ko00000	-	-	-	T2SSE
NFNHFNFO_01771	33035.JPJF01000026_gene2708	5.44e-72	220.0	COG1896@1|root,COG1896@2|Bacteria,1V4MY@1239|Firmicutes,25CES@186801|Clostridia,3Y0P3@572511|Blautia	186801|Clostridia	S	HD domain	-	-	-	ko:K07023	-	-	-	-	ko00000	-	-	-	HD_3
NFNHFNFO_01772	33035.JPJF01000026_gene2709	0.0	1261.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia	186801|Clostridia	G	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
NFNHFNFO_01773	33035.JPJF01000026_gene2710	1.05e-183	514.0	COG2207@1|root,COG2207@2|Bacteria,1V2Q5@1239|Firmicutes,24GBK@186801|Clostridia	186801|Clostridia	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_01774	33035.JPJF01000026_gene2711	9.01e-56	177.0	COG0789@1|root,COG0789@2|Bacteria,1V6C0@1239|Firmicutes,24KFZ@186801|Clostridia,3Y0SI@572511|Blautia	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NFNHFNFO_01775	33035.JPJF01000026_gene2712	1.38e-227	628.0	COG0667@1|root,COG0667@2|Bacteria,1TRS0@1239|Firmicutes,247RJ@186801|Clostridia,3XZQB@572511|Blautia	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	ko:K19265	-	-	-	-	ko00000,ko01000	-	-	-	Aldo_ket_red
NFNHFNFO_01776	33035.JPJF01000026_gene2713	5.1e-113	327.0	COG2091@1|root,COG2091@2|Bacteria,1UFUD@1239|Firmicutes,25MRV@186801|Clostridia,3Y03Q@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	sfp	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
NFNHFNFO_01777	33035.JPJF01000026_gene2714	0.0	1179.0	COG0210@1|root,COG0210@2|Bacteria,1TPVG@1239|Firmicutes,2484I@186801|Clostridia,3XYTS@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	yjcD	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
NFNHFNFO_01778	33035.JPJF01000026_gene2715	0.0	926.0	COG0008@1|root,COG0008@2|Bacteria,1TPJC@1239|Firmicutes,2482P@186801|Clostridia,3XZIU@572511|Blautia	186801|Clostridia	H	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)	gltX	-	6.1.1.17,6.1.1.24	ko:K01885,ko:K09698	ko00860,ko00970,ko01100,ko01110,ko01120,map00860,map00970,map01100,map01110,map01120	M00121,M00359,M00360	R03651,R05578	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko02048,ko03016	-	-	-	tRNA-synt_1c
NFNHFNFO_01779	658086.HMPREF0994_01166	2.11e-257	728.0	COG3533@1|root,COG3533@2|Bacteria,1TRI1@1239|Firmicutes,248CA@186801|Clostridia,27KWK@186928|unclassified Lachnospiraceae	186801|Clostridia	N	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,Glyco_hydro_127,Laminin_G_3
NFNHFNFO_01780	180332.JTGN01000009_gene4322	3.32e-31	120.0	COG5578@1|root,COG5578@2|Bacteria,1VI97@1239|Firmicutes,24TB6@186801|Clostridia	186801|Clostridia	S	Protein of unknown function, DUF624	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
NFNHFNFO_01781	1280671.AUJH01000003_gene1366	8.3e-165	465.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia,4C1Y3@830|Butyrivibrio	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_01782	1280671.AUJH01000003_gene1365	4.76e-178	500.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia,4BWU0@830|Butyrivibrio	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_01783	1280671.AUJH01000003_gene1364	6.26e-230	644.0	COG1653@1|root,COG1653@2|Bacteria,1U0QV@1239|Firmicutes,24BVP@186801|Clostridia,4BYQK@830|Butyrivibrio	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
NFNHFNFO_01784	1280671.AUJH01000003_gene1363	2.64e-45	156.0	COG2207@1|root,COG2207@2|Bacteria,1V2Q5@1239|Firmicutes,24GBK@186801|Clostridia	186801|Clostridia	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_01786	33035.JPJF01000026_gene2716	1.43e-111	320.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24FZI@186801|Clostridia,3XZZI@572511|Blautia	186801|Clostridia	C	COG COG2080 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS homologs	cutS	-	1.2.5.3	ko:K03518	-	-	R11168	RC02800	ko00000,ko01000	-	-	-	Fer2,Fer2_2
NFNHFNFO_01787	33035.JPJF01000026_gene2717	5.46e-185	517.0	COG1319@1|root,COG1319@2|Bacteria,1TQA5@1239|Firmicutes,248WI@186801|Clostridia,3XZ4A@572511|Blautia	186801|Clostridia	C	COG COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs	xdhB	-	1.17.1.4	ko:K13479	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	CO_deh_flav_C,FAD_binding_5
NFNHFNFO_01788	33035.JPJF01000026_gene2718	0.0	1473.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3XZHI@572511|Blautia	186801|Clostridia	C	COG COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	xdhA	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
NFNHFNFO_01789	33035.JPJF01000026_gene2719	8.96e-293	801.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3XZ7R@572511|Blautia	186801|Clostridia	F	COG COG0402 Cytosine deaminase and related metal-dependent hydrolases	guaD	-	3.5.4.3	ko:K01487	ko00230,ko01100,map00230,map01100	-	R01676	RC00204	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NFNHFNFO_01790	556261.HMPREF0240_00903	7.96e-256	704.0	COG5012@1|root,COG5012@2|Bacteria,1UF8A@1239|Firmicutes,24CAU@186801|Clostridia	186801|Clostridia	S	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01791	556261.HMPREF0240_00902	0.0	1170.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia,36FJR@31979|Clostridiaceae	186801|Clostridia	G	Domain of unknown function (DUF5110)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5110,Glyco_hydro_31
NFNHFNFO_01792	556261.HMPREF0240_00901	2.75e-154	438.0	COG0395@1|root,COG0395@2|Bacteria,1TSJK@1239|Firmicutes,25C5J@186801|Clostridia,36WPT@31979|Clostridiaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_01793	556261.HMPREF0240_00900	5.99e-163	461.0	COG1175@1|root,COG1175@2|Bacteria,1UEPI@1239|Firmicutes,25C57@186801|Clostridia,36WPS@31979|Clostridiaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_01794	1232453.BAIF02000087_gene265	5.3e-232	660.0	COG2972@1|root,COG2972@2|Bacteria,1TS61@1239|Firmicutes,247ZZ@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	His_kinase
NFNHFNFO_01795	556261.HMPREF0240_00898	8.77e-124	359.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24FGY@186801|Clostridia,36GPE@31979|Clostridiaceae	186801|Clostridia	K	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
NFNHFNFO_01796	556261.HMPREF0240_00897	6.68e-253	701.0	COG1653@1|root,COG1653@2|Bacteria,1TRMK@1239|Firmicutes,24BMJ@186801|Clostridia,36GI7@31979|Clostridiaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
NFNHFNFO_01797	33035.JPJF01000026_gene2722	0.0	1087.0	COG3525@1|root,COG3525@2|Bacteria,1TRN0@1239|Firmicutes,24CTA@186801|Clostridia,3Y0RI@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolase family 20, catalytic domain	-	-	3.2.1.52	ko:K12373	ko00511,ko00513,ko00520,ko00531,ko00603,ko00604,ko01100,ko04142,map00511,map00513,map00520,map00531,map00603,map00604,map01100,map04142	M00079	R00022,R06004,R11316	RC00049	ko00000,ko00001,ko00002,ko01000,ko03110	-	GH20	-	Glyco_hydro_20
NFNHFNFO_01798	33035.JPJF01000026_gene2723	5.74e-52	165.0	2BAVH@1|root,324B1@2|Bacteria,1UQMR@1239|Firmicutes,24UDK@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01799	33035.JPJF01000026_gene2724	6.17e-229	632.0	COG2070@1|root,COG2070@2|Bacteria,1TPX1@1239|Firmicutes,247YZ@186801|Clostridia,3XZHK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NMO
NFNHFNFO_01800	537007.BLAHAN_05168	7.55e-300	832.0	COG0777@1|root,COG0825@1|root,COG0777@2|Bacteria,COG0825@2|Bacteria,1TP4U@1239|Firmicutes,248QK@186801|Clostridia,3XYX8@572511|Blautia	186801|Clostridia	I	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA	accD	-	2.1.3.15,6.4.1.2	ko:K01962,ko:K01963	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04386	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20740	ACCA,Carboxyl_trans
NFNHFNFO_01801	33035.JPJF01000047_gene872	1.29e-313	855.0	COG0439@1|root,COG0439@2|Bacteria,1TP16@1239|Firmicutes,25E48@186801|Clostridia,3XZMB@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	accC	-	6.3.4.14,6.4.1.2	ko:K01961	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742,R04385	RC00040,RC00253,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	-	Biotin_carb_C,Biotin_carb_N,CPSase_L_D2
NFNHFNFO_01802	33035.JPJF01000047_gene873	4.28e-92	270.0	COG0764@1|root,COG0764@2|Bacteria,1V6EX@1239|Firmicutes,24JAW@186801|Clostridia,3Y04Q@572511|Blautia	186801|Clostridia	I	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs	fabZ	-	4.2.1.59	ko:K02372	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04428,R04535,R04537,R04544,R04568,R04954,R04965,R07764,R10117,R10121	RC00831,RC01095	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	FabA
NFNHFNFO_01803	33035.JPJF01000047_gene874	2.42e-100	292.0	COG0511@1|root,COG0511@2|Bacteria,1VAB7@1239|Firmicutes,24MNP@186801|Clostridia,3Y0FB@572511|Blautia	186801|Clostridia	I	first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA	accB	-	-	ko:K02160	ko00061,ko00620,ko00640,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,map00061,map00620,map00640,map00720,map01100,map01110,map01120,map01130,map01200,map01212	M00082,M00376	R00742	RC00040,RC00367	ko00000,ko00001,ko00002	-	-	iHN637.CLJU_RS20755	Biotin_lipoyl
NFNHFNFO_01804	33035.JPJF01000047_gene875	7.39e-293	800.0	COG0304@1|root,COG0304@2|Bacteria,1TPA7@1239|Firmicutes,247VF@186801|Clostridia,3XZBB@572511|Blautia	186801|Clostridia	I	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP	fabF	-	2.3.1.179	ko:K09458	ko00061,ko00780,ko01100,ko01212,map00061,map00780,map01100,map01212	M00083,M00572	R04355,R04726,R04952,R04957,R04960,R04963,R04968,R07762,R10115,R10119	RC00039,RC02728,RC02729,RC02888	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Ketoacyl-synt_C,ketoacyl-synt
NFNHFNFO_01805	33035.JPJF01000047_gene876	1.1e-154	436.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3XYM7@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	fabG	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
NFNHFNFO_01806	33035.JPJF01000047_gene877	3.18e-194	542.0	COG0331@1|root,COG0331@2|Bacteria,1TPB7@1239|Firmicutes,247UF@186801|Clostridia,3XZKW@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	fabD	-	2.3.1.39	ko:K00645	ko00061,ko00333,ko01100,ko01130,ko01212,map00061,map00333,map01100,map01130,map01212	M00082	R01626,R11671	RC00004,RC00039,RC02727	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyl_transf_1
NFNHFNFO_01807	33035.JPJF01000047_gene878	9.9e-42	137.0	COG0236@1|root,COG0236@2|Bacteria,1VEE3@1239|Firmicutes,24QME@186801|Clostridia,3Y0HG@572511|Blautia	186801|Clostridia	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	acpP	-	-	ko:K02078	-	-	-	-	ko00000,ko00001	-	-	-	PP-binding
NFNHFNFO_01808	33035.JPJF01000047_gene879	9.7e-274	751.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3XYUT@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
NFNHFNFO_01809	33035.JPJF01000047_gene880	0.0	1113.0	COG0584@1|root,COG0584@2|Bacteria,1UGF1@1239|Firmicutes,25E4R@186801|Clostridia,3Y139@572511|Blautia	186801|Clostridia	C	Membrane domain of glycerophosphoryl diester phosphodiesterase	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD,GPDPase_memb
NFNHFNFO_01810	33035.JPJF01000047_gene881	4.17e-119	340.0	2C2RJ@1|root,33VFU@2|Bacteria,1VV8Z@1239|Firmicutes,250DV@186801|Clostridia,3Y08E@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01811	33035.JPJF01000047_gene882	1e-96	281.0	COG4747@1|root,COG4747@2|Bacteria,1V7U2@1239|Firmicutes,24JE5@186801|Clostridia,3Y2DE@572511|Blautia	186801|Clostridia	S	ACT domain	-	-	-	-	-	-	-	-	-	-	-	-	ACT
NFNHFNFO_01812	33035.JPJF01000047_gene883	1.89e-316	862.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,3XZFD@572511|Blautia	186801|Clostridia	H	AMP-binding enzyme C-terminal domain	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2
NFNHFNFO_01813	33035.JPJF01000047_gene884	1.24e-59	184.0	2EHCX@1|root,33B4S@2|Bacteria,1VKA0@1239|Firmicutes,259R7@186801|Clostridia,3Y0T8@572511|Blautia	186801|Clostridia	S	Spore coat associated protein JA (CotJA)	-	-	-	-	-	-	-	-	-	-	-	-	CotJA
NFNHFNFO_01814	33035.JPJF01000047_gene885	1.99e-57	177.0	2E34J@1|root,32Y4N@2|Bacteria,1VESM@1239|Firmicutes,24QZX@186801|Clostridia,3Y0NH@572511|Blautia	186801|Clostridia	S	COG NOG18028 non supervised orthologous group	cotJB	-	-	ko:K06333	-	-	-	-	ko00000	-	-	-	CotJB
NFNHFNFO_01815	33035.JPJF01000047_gene886	9.54e-40	132.0	COG3546@1|root,COG3546@2|Bacteria,1UF7I@1239|Firmicutes,25K8A@186801|Clostridia,3Y21Y@572511|Blautia	186801|Clostridia	P	Manganese containing catalase	-	-	-	-	-	-	-	-	-	-	-	-	Mn_catalase
NFNHFNFO_01816	33035.JPJF01000047_gene887	1.42e-295	818.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,3XYZX@572511|Blautia	186801|Clostridia	L	COG COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NFNHFNFO_01818	33035.JPJF01000047_gene889	8.97e-38	127.0	2A2DC@1|root,30QQD@2|Bacteria,1UGEZ@1239|Firmicutes,25NVE@186801|Clostridia,3Y22X@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01819	33035.JPJF01000047_gene890	2.71e-188	523.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia,3Y15M@572511|Blautia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	kduD	-	1.1.1.127,1.1.1.69	ko:K00046,ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
NFNHFNFO_01820	33035.JPJF01000047_gene891	1.1e-244	673.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,25B0S@186801|Clostridia,3Y2DN@572511|Blautia	186801|Clostridia	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.380	ko:K08322	ko00040,ko01100,map00040,map01100	-	R10848	RC00085	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_01821	33035.JPJF01000047_gene892	1.05e-291	798.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3XZAD@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K11690	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctM
NFNHFNFO_01822	33035.JPJF01000047_gene893	4.51e-101	294.0	COG3090@1|root,COG3090@2|Bacteria	2|Bacteria	G	Trap-type c4-dicarboxylate transport system, small permease component	-	-	-	ko:K11689	ko02020,map02020	-	-	-	ko00000,ko00001,ko02000	2.A.56.1	-	-	DctQ
NFNHFNFO_01823	33035.JPJF01000047_gene894	1.51e-216	600.0	COG1638@1|root,COG1638@2|Bacteria,1TP3I@1239|Firmicutes,248MN@186801|Clostridia,3Y06Q@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
NFNHFNFO_01824	33035.JPJF01000047_gene895	3.48e-309	841.0	COG4948@1|root,COG4948@2|Bacteria,1TS0S@1239|Firmicutes,24AE7@186801|Clostridia,3Y0NS@572511|Blautia	186801|Clostridia	M	Mandelate racemase / muconate lactonizing enzyme, N-terminal domain	-	-	4.2.1.5	ko:K01683	-	-	-	-	ko00000,ko01000	-	-	-	MR_MLE_C,MR_MLE_N
NFNHFNFO_01825	33035.JPJF01000047_gene896	6.87e-153	430.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,3Y0CT@572511|Blautia	186801|Clostridia	K	FCD	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
NFNHFNFO_01826	33035.JPJF01000047_gene899	0.0	866.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3XZ7Z@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_01827	33035.JPJF01000047_gene900	2.82e-211	585.0	COG2207@1|root,COG2207@2|Bacteria,1UYSR@1239|Firmicutes,248R9@186801|Clostridia,3Y2A2@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NFNHFNFO_01828	33035.JPJF01000047_gene901	0.0	1324.0	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,24ARZ@186801|Clostridia,3Y168@572511|Blautia	186801|Clostridia	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
NFNHFNFO_01829	33035.JPJF01000047_gene902	5.98e-167	472.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia	186801|Clostridia	S	PHP domain	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
NFNHFNFO_01830	33035.JPJF01000047_gene903	1.79e-261	722.0	COG2270@1|root,COG2270@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K06902	ko04138,map04138	-	-	-	ko00000,ko00001,ko02000,ko04131	2.A.1.24,9.A.15.1	-	-	MFS_1
NFNHFNFO_01831	33035.JPJF01000047_gene904	4.69e-212	590.0	COG1940@1|root,COG1940@2|Bacteria,1V1AM@1239|Firmicutes,25B1Z@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
NFNHFNFO_01832	33035.JPJF01000047_gene905	2.38e-127	362.0	COG5423@1|root,COG5423@2|Bacteria,1V8BX@1239|Firmicutes,24JN8@186801|Clostridia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NFNHFNFO_01833	33035.JPJF01000007_gene2071	2.82e-72	219.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,3XYJ2@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
NFNHFNFO_01834	478749.BRYFOR_08826	5.15e-302	831.0	COG1961@1|root,COG1961@2|Bacteria,1TS5B@1239|Firmicutes,248MZ@186801|Clostridia	186801|Clostridia	L	resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NFNHFNFO_01835	1235798.C817_00833	7.82e-30	105.0	2EVS2@1|root,33P5Z@2|Bacteria,1VN4H@1239|Firmicutes,24UY8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01836	1235798.C817_00832	2.63e-131	377.0	COG1396@1|root,COG1396@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,HTH_31
NFNHFNFO_01837	665950.HMPREF1025_00250	2.47e-67	204.0	COG0526@1|root,COG0526@2|Bacteria,1VEYC@1239|Firmicutes,24QMF@186801|Clostridia,27PJ6@186928|unclassified Lachnospiraceae	186801|Clostridia	CO	Thioredoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin_3
NFNHFNFO_01838	742723.HMPREF9477_00306	3.33e-222	615.0	COG0701@1|root,COG0701@2|Bacteria,1TQC7@1239|Firmicutes,24A02@186801|Clostridia,27J6U@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Predicted permease	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_1
NFNHFNFO_01839	411460.RUMTOR_00521	9.56e-68	205.0	COG0640@1|root,COG0640@2|Bacteria,1VEER@1239|Firmicutes,24QZK@186801|Clostridia,3Y05B@572511|Blautia	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	arsR	-	-	ko:K03892	-	-	-	-	ko00000,ko03000	-	-	-	HTH_20,HTH_5
NFNHFNFO_01840	1232447.BAHW02000013_gene635	4.06e-117	354.0	28JIM@1|root,2Z9BV@2|Bacteria,1TRP9@1239|Firmicutes,24DM5@186801|Clostridia,269C1@186813|unclassified Clostridiales	186801|Clostridia	S	Psort location Cytoplasmic, score 8.96	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01841	1232447.BAHW02000013_gene637	0.0	920.0	COG3378@1|root,COG3378@2|Bacteria,1TQP9@1239|Firmicutes	1239|Firmicutes	L	Phage plasmid primase, P4 family	-	-	-	-	-	-	-	-	-	-	-	-	D5_N,Pox_D5
NFNHFNFO_01842	33035.JPJF01000007_gene2070	5.75e-119	340.0	COG2032@1|root,COG2032@2|Bacteria,1V3HM@1239|Firmicutes,24HGH@186801|Clostridia,3Y1RM@572511|Blautia	186801|Clostridia	P	Copper/zinc superoxide dismutase (SODC)	sodC	-	1.15.1.1	ko:K04565	ko04146,ko04213,ko05014,ko05016,ko05020,map04146,map04213,map05014,map05016,map05020	-	-	-	ko00000,ko00001,ko01000	-	-	-	Sod_Cu
NFNHFNFO_01843	33035.JPJF01000007_gene2069	2.59e-175	489.0	COG1342@1|root,COG1433@1|root,COG1342@2|Bacteria,COG1433@2|Bacteria,1TRMQ@1239|Firmicutes,25E8C@186801|Clostridia,3XZY2@572511|Blautia	186801|Clostridia	S	Dinitrogenase iron-molybdenum cofactor	-	-	-	-	-	-	-	-	-	-	-	-	DUF134,Nitro_FeMo-Co
NFNHFNFO_01844	33035.JPJF01000007_gene2068	4.81e-264	727.0	COG1979@1|root,COG1979@2|Bacteria,1TPS3@1239|Firmicutes,248DW@186801|Clostridia,3XZHU@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K19955	-	-	-	-	ko00000,ko01000	-	-	-	Fe-ADH
NFNHFNFO_01845	33035.JPJF01000007_gene2067	4.62e-275	751.0	COG1453@1|root,COG1453@2|Bacteria,1TSTA@1239|Firmicutes,249IP@186801|Clostridia,3Y032@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red,Fer4,Fer4_17
NFNHFNFO_01846	33035.JPJF01000007_gene2066	2.32e-233	641.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,3Y086@572511|Blautia	186801|Clostridia	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	DLH,FSH1,Hydrolase_4
NFNHFNFO_01847	33035.JPJF01000007_gene2065	0.0	1496.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3XZ46@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF5110)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4968,DUF5110,Glyco_hydro_31
NFNHFNFO_01848	33035.JPJF01000007_gene2064	0.0	994.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia,3Y16R@572511|Blautia	186801|Clostridia	L	DbpA RNA binding domain	cshA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
NFNHFNFO_01849	33035.JPJF01000007_gene2063	2.12e-128	374.0	2DPUG@1|root,333EN@2|Bacteria,1VIIY@1239|Firmicutes,24QQ5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01850	33035.JPJF01000007_gene2062	2.29e-122	351.0	COG0652@1|root,COG0652@2|Bacteria,1V1SP@1239|Firmicutes,24G4H@186801|Clostridia,3XZUZ@572511|Blautia	186801|Clostridia	M	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	-	-	5.2.1.8	ko:K01802	-	-	-	-	ko00000,ko01000	-	-	-	Pro_isomerase
NFNHFNFO_01851	33035.JPJF01000007_gene2061	5.67e-90	265.0	COG3708@1|root,COG3708@2|Bacteria,1V7HJ@1239|Firmicutes,24KUR@186801|Clostridia	186801|Clostridia	K	PFAM Bacterial transcription activator, effector binding	-	-	-	-	-	-	-	-	-	-	-	-	Cass2,Zn_ribbon_2
NFNHFNFO_01852	33035.JPJF01000007_gene2060	5.87e-198	551.0	COG2378@1|root,COG2378@2|Bacteria,1TT23@1239|Firmicutes,248A8@186801|Clostridia,3Y0U0@572511|Blautia	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
NFNHFNFO_01853	33035.JPJF01000007_gene2059	1.06e-142	407.0	COG0778@1|root,COG1145@1|root,COG0778@2|Bacteria,COG1145@2|Bacteria,1TPKH@1239|Firmicutes,249WN@186801|Clostridia	186801|Clostridia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_4,Fer4_6,Nitroreductase
NFNHFNFO_01854	33035.JPJF01000007_gene2058	3e-147	416.0	COG1285@1|root,COG1285@2|Bacteria,1V409@1239|Firmicutes,249SQ@186801|Clostridia,3Y1KF@572511|Blautia	186801|Clostridia	S	MgtC family	-	-	-	ko:K07507	-	-	-	-	ko00000,ko02000	9.B.20	-	-	MgtC
NFNHFNFO_01855	33035.JPJF01000007_gene2057	5.66e-169	474.0	COG0122@1|root,COG0122@2|Bacteria,1TQAF@1239|Firmicutes,2495X@186801|Clostridia,3XZBG@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	alkA	-	4.2.99.18	ko:K03660	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	HhH-GPD,OGG_N
NFNHFNFO_01856	33035.JPJF01000007_gene2056	8.93e-192	534.0	COG0688@1|root,COG0688@2|Bacteria,1TR34@1239|Firmicutes,248VU@186801|Clostridia,3XYYF@572511|Blautia	186801|Clostridia	I	Phosphatidylserine decarboxylase	psd	-	4.1.1.65	ko:K01613	ko00564,ko01100,ko01110,map00564,map01100,map01110	M00093	R02055	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	PS_Dcarbxylase
NFNHFNFO_01857	33035.JPJF01000007_gene2055	8.79e-125	358.0	COG1183@1|root,COG1183@2|Bacteria,1TTB7@1239|Firmicutes,24GPU@186801|Clostridia,3XZVV@572511|Blautia	186801|Clostridia	I	CDP-alcohol phosphatidyltransferase	-	-	2.7.8.8	ko:K17103	ko00260,ko00564,ko01100,ko01110,map00260,map00564,map01100,map01110	M00093	R01800	RC00002,RC00017,RC02795	ko00000,ko00001,ko00002,ko01000	-	-	-	CDP-OH_P_transf
NFNHFNFO_01858	33035.JPJF01000007_gene2054	2.57e-230	636.0	COG0392@1|root,COG0392@2|Bacteria,1TXG8@1239|Firmicutes,24A1A@186801|Clostridia,3XZ24@572511|Blautia	186801|Clostridia	S	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms	mprF	-	-	ko:K07027	-	-	-	-	ko00000,ko02000	4.D.2	-	-	LPG_synthase_TM
NFNHFNFO_01859	33035.JPJF01000007_gene2053	1.01e-166	466.0	COG0671@1|root,COG0671@2|Bacteria,1V2PZ@1239|Firmicutes,24DHR@186801|Clostridia,3Y014@572511|Blautia	186801|Clostridia	I	PAP2 superfamily	-	-	-	-	-	-	-	-	-	-	-	-	PAP2_3
NFNHFNFO_01860	33035.JPJF01000007_gene2052	0.0	4261.0	COG1196@1|root,COG1409@1|root,COG3507@1|root,COG3533@1|root,COG4412@1|root,COG1196@2|Bacteria,COG1409@2|Bacteria,COG3507@2|Bacteria,COG3533@2|Bacteria,COG4412@2|Bacteria,1U157@1239|Firmicutes,25E8B@186801|Clostridia	186801|Clostridia	U	Concanavalin A-like lectin/glucanases superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Big_4,FIVAR,Laminin_G_3
NFNHFNFO_01861	33035.JPJF01000007_gene2051	3.16e-220	610.0	COG1609@1|root,COG1609@2|Bacteria,1TRWK@1239|Firmicutes,24DAV@186801|Clostridia,3Y29V@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_01862	33035.JPJF01000007_gene2050	0.0	3891.0	COG1196@1|root,COG5263@1|root,COG5520@1|root,COG1196@2|Bacteria,COG5263@2|Bacteria,COG5520@2|Bacteria,1UUUF@1239|Firmicutes,25KCG@186801|Clostridia,3Y1M0@572511|Blautia	186801|Clostridia	DG	FIVAR domain	-	-	-	-	-	-	-	-	-	-	-	-	FIVAR
NFNHFNFO_01863	33035.JPJF01000007_gene2048	1.29e-241	670.0	COG2207@1|root,COG2207@2|Bacteria,1TQD7@1239|Firmicutes,24DSW@186801|Clostridia,3Y1J2@572511|Blautia	1239|Firmicutes	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
NFNHFNFO_01864	33035.JPJF01000007_gene2047	0.0	1717.0	COG0574@1|root,COG1080@1|root,COG0574@2|Bacteria,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,247RW@186801|Clostridia,3XZCJ@572511|Blautia	186801|Clostridia	G	Phosphoenolpyruvate synthase pyruvate phosphate dikinase	ppdK	-	2.7.9.1	ko:K01006	ko00620,ko00710,ko00720,ko01100,ko01120,ko01200,map00620,map00710,map00720,map01100,map01120,map01200	M00169,M00171,M00172,M00173	R00206	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000	-	-	-	PEP-utilizers,PEP-utilizers_C,PPDK_N
NFNHFNFO_01865	33035.JPJF01000007_gene2046	1.01e-200	558.0	COG4989@1|root,COG4989@2|Bacteria,1TQ12@1239|Firmicutes,248NF@186801|Clostridia,3XZFK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NFNHFNFO_01866	33035.JPJF01000007_gene2045	1.01e-260	722.0	COG0624@1|root,COG0624@2|Bacteria,1TPEG@1239|Firmicutes,247SK@186801|Clostridia,3Y17X@572511|Blautia	186801|Clostridia	E	Peptidase family M20/M25/M40	-	-	3.5.1.18	ko:K01439	ko00300,ko01100,ko01120,ko01230,map00300,map01100,map01120,map01230	M00016	R02734	RC00064,RC00090	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20
NFNHFNFO_01867	33035.JPJF01000007_gene2044	3.61e-262	724.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,3XYV4@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
NFNHFNFO_01868	33035.JPJF01000007_gene2043	5.34e-310	850.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQYB@1239|Firmicutes,24ERE@186801|Clostridia,3Y1DE@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
NFNHFNFO_01869	33035.JPJF01000007_gene2042	2.47e-188	524.0	COG0395@1|root,COG0395@2|Bacteria,1UYHV@1239|Firmicutes,25C4Q@186801|Clostridia,3Y2EC@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_01870	33035.JPJF01000007_gene2041	7.52e-207	572.0	COG1175@1|root,COG1175@2|Bacteria,1TQB1@1239|Firmicutes,25C4P@186801|Clostridia,3XZG3@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_01871	33035.JPJF01000007_gene2040	6.91e-277	761.0	COG1653@1|root,COG1653@2|Bacteria,1TQJE@1239|Firmicutes,2496C@186801|Clostridia,3XZ5U@572511|Blautia	186801|Clostridia	G	ABC transporter periplasmic binding protein YcjN precursor	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_01872	33035.JPJF01000007_gene2039	3.99e-209	580.0	COG0407@1|root,COG0407@2|Bacteria,1U2YS@1239|Firmicutes,25NJV@186801|Clostridia,3Y1DD@572511|Blautia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_01873	33035.JPJF01000007_gene2038	0.0	1115.0	COG2972@1|root,COG2972@2|Bacteria,1UYEW@1239|Firmicutes,24CU0@186801|Clostridia,3Y1BF@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NFNHFNFO_01874	33035.JPJF01000007_gene2037	2.22e-296	809.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3XZA1@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NFNHFNFO_01875	33035.JPJF01000007_gene2036	3.1e-248	689.0	COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,24950@186801|Clostridia,3XZ1F@572511|Blautia	186801|Clostridia	M	Bacterial capsule synthesis protein PGA_cap	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
NFNHFNFO_01876	33035.JPJF01000007_gene2035	5.63e-100	296.0	COG0671@1|root,COG0671@2|Bacteria,1V7SI@1239|Firmicutes,24FWW@186801|Clostridia	186801|Clostridia	I	PAP2 superfamily	-	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
NFNHFNFO_01877	33035.JPJF01000007_gene2034	6.42e-120	346.0	COG1476@1|root,COG1476@2|Bacteria,1UUSK@1239|Firmicutes,247YW@186801|Clostridia,3Y062@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Zn_ribbon_2
NFNHFNFO_01879	33035.JPJF01000007_gene2033	3.85e-197	546.0	COG0395@1|root,COG0395@2|Bacteria,1UCH2@1239|Firmicutes,24AS5@186801|Clostridia,3XZF4@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_01880	33035.JPJF01000007_gene2032	3.96e-197	548.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,249MK@186801|Clostridia,3XZBN@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	msmF	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_01881	33035.JPJF01000007_gene2031	1.46e-300	821.0	COG1653@1|root,COG1653@2|Bacteria,1TR8U@1239|Firmicutes,25E8A@186801|Clostridia,3XZJY@572511|Blautia	186801|Clostridia	G	ABC transporter periplasmic binding protein YcjN precursor	-	-	-	ko:K10120	-	M00197	-	-	ko00000,ko00002,ko02000	3.A.1.1.20	-	-	SBP_bac_8
NFNHFNFO_01882	33035.JPJF01000007_gene2030	0.0	973.0	COG1621@1|root,COG1621@2|Bacteria,1TPAE@1239|Firmicutes,247UU@186801|Clostridia,3Y12M@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 32	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_32C,Glyco_hydro_32N
NFNHFNFO_01883	33035.JPJF01000007_gene2029	3.05e-230	635.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3XZ8Q@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529,ko:K03484	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NFNHFNFO_01884	33035.JPJF01000007_gene2028	0.0	962.0	COG0423@1|root,COG0423@2|Bacteria,1TP94@1239|Firmicutes,248FB@186801|Clostridia,3XZ0N@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of glycine to tRNA(Gly)	glyQS	GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101	6.1.1.14	ko:K01880	ko00970,map00970	M00359,M00360	R03654	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	HGTP_anticodon,tRNA-synt_2b
NFNHFNFO_01885	33035.JPJF01000007_gene2027	9.58e-167	467.0	COG1381@1|root,COG1381@2|Bacteria,1UZ19@1239|Firmicutes,249TI@186801|Clostridia,3XYR9@572511|Blautia	186801|Clostridia	L	Involved in DNA repair and RecF pathway recombination	recO	-	-	ko:K03584	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	RecO_C,RecO_N
NFNHFNFO_01886	33035.JPJF01000007_gene2026	5.31e-210	581.0	COG1159@1|root,COG1159@2|Bacteria,1TP3R@1239|Firmicutes,24876@186801|Clostridia,3XYUU@572511|Blautia	186801|Clostridia	S	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism	era	-	-	ko:K03595	-	-	-	-	ko00000,ko03009,ko03029	-	-	-	KH_2,MMR_HSR1
NFNHFNFO_01887	33035.JPJF01000007_gene2025	0.0	1834.0	COG1026@1|root,COG1026@2|Bacteria,1TPD1@1239|Firmicutes,25ACE@186801|Clostridia,3XZNB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06972	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M16C_assoc,Peptidase_M16,Peptidase_M16_C
NFNHFNFO_01888	33035.JPJF01000007_gene2024	2.54e-147	422.0	2EC0M@1|root,30HYA@2|Bacteria,1UUUE@1239|Firmicutes,258KM@186801|Clostridia,3Y0WI@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01889	537007.BLAHAN_06799	1.39e-123	355.0	COG0461@1|root,COG0461@2|Bacteria,1V23H@1239|Firmicutes,24FTS@186801|Clostridia,3XZRS@572511|Blautia	186801|Clostridia	F	orotate phosphoribosyltransferase K00762	-	-	2.4.2.10	ko:K00762	ko00240,ko01100,map00240,map01100	M00051	R01870	RC00611	ko00000,ko00001,ko00002,ko01000	-	-	-	-
NFNHFNFO_01890	33035.JPJF01000116_gene2610	3.63e-153	432.0	COG0584@1|root,COG0584@2|Bacteria,1V3W4@1239|Firmicutes,24AVJ@186801|Clostridia,3XZZF@572511|Blautia	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	3.1.4.46	ko:K01126	ko00564,map00564	-	R01030,R01470	RC00017,RC00425	ko00000,ko00001,ko01000	-	-	-	GDPD
NFNHFNFO_01891	33035.JPJF01000116_gene2609	3.5e-78	233.0	COG3428@1|root,COG3428@2|Bacteria,1V9YB@1239|Firmicutes,24MQT@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	bPH_2
NFNHFNFO_01892	33035.JPJF01000116_gene2608	0.0	2317.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,3XZ4K@572511|Blautia	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
NFNHFNFO_01893	33035.JPJF01000116_gene2607	4.22e-86	254.0	COG1959@1|root,COG1959@2|Bacteria,1VA5B@1239|Firmicutes,24JMN@186801|Clostridia,3Y09T@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NFNHFNFO_01894	33035.JPJF01000116_gene2606	0.0	1051.0	COG0488@1|root,COG0488@2|Bacteria,1TPW0@1239|Firmicutes,248ST@186801|Clostridia,3XZ1S@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	ykpA	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,ABC_tran_Xtn
NFNHFNFO_01895	33035.JPJF01000116_gene2605	1.3e-268	739.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,3XZ9R@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
NFNHFNFO_01896	33035.JPJF01000116_gene2604	3.16e-175	491.0	COG0583@1|root,COG0583@2|Bacteria,1UXNN@1239|Firmicutes,25M7W@186801|Clostridia,3Y23K@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_01897	33035.JPJF01000116_gene2603	6.33e-24	100.0	COG4372@1|root,COG4372@2|Bacteria,1UH4U@1239|Firmicutes,25PTF@186801|Clostridia,3Y23N@572511|Blautia	186801|Clostridia	S	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01898	33035.JPJF01000116_gene2602	3.36e-158	447.0	COG1670@1|root,COG1670@2|Bacteria,1TQUK@1239|Firmicutes,24BF7@186801|Clostridia	186801|Clostridia	J	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	GNAT_acetyltran
NFNHFNFO_01899	33035.JPJF01000116_gene2601	2.39e-93	273.0	COG1846@1|root,COG1846@2|Bacteria,1VJU1@1239|Firmicutes,24JW2@186801|Clostridia	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27
NFNHFNFO_01900	33035.JPJF01000116_gene2600	1.03e-301	825.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYX6@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_01901	33035.JPJF01000116_gene2599	3e-186	521.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3XYHF@572511|Blautia	186801|Clostridia	GK	Psort location Cytoplasmic, score	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
NFNHFNFO_01902	33035.JPJF01000116_gene2598	6.49e-245	673.0	COG0208@1|root,COG0208@2|Bacteria,1TQTH@1239|Firmicutes,249AN@186801|Clostridia,3XZSE@572511|Blautia	186801|Clostridia	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdB	-	1.17.4.1	ko:K00526	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	Ribonuc_red_sm
NFNHFNFO_01903	33035.JPJF01000116_gene2597	0.0	1589.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,3XYGW@572511|Blautia	186801|Clostridia	F	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides	nrdA	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,RNR_N,Ribonuc_red_lgC,Ribonuc_red_lgN
NFNHFNFO_01904	411467.BACCAP_00543	0.0	1675.0	COG1038@1|root,COG1038@2|Bacteria,1UHP9@1239|Firmicutes,25E5B@186801|Clostridia,2687J@186813|unclassified Clostridiales	186801|Clostridia	C	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second	pyc	-	6.4.1.1	ko:K01958	ko00020,ko00620,ko00720,ko01100,ko01120,ko01200,ko01230,map00020,map00620,map00720,map01100,map01120,map01200,map01230	M00173	R00344	RC00040,RC00367	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS18410	Biotin_carb_C,Biotin_carb_N,Biotin_lipoyl,CPSase_L_D2,HMGL-like,PYC_OADA
NFNHFNFO_01905	33035.JPJF01000096_gene2091	0.0	1018.0	COG0753@1|root,COG0753@2|Bacteria,1TPPV@1239|Firmicutes,247Y1@186801|Clostridia	186801|Clostridia	C	Serves to protect cells from the toxic effects of hydrogen peroxide	katA	-	1.11.1.6	ko:K03781	ko00380,ko00630,ko01110,ko01130,ko01200,ko04011,ko04016,ko04068,ko04146,ko04211,ko04212,ko04213,ko05014,map00380,map00630,map01110,map01130,map01200,map04011,map04016,map04068,map04146,map04211,map04212,map04213,map05014	M00532	R00009,R00602,R02670	RC00034,RC00767,RC02141,RC02755	ko00000,ko00001,ko00002,ko01000	-	-	-	Catalase,Catalase-rel
NFNHFNFO_01906	1111454.HMPREF1250_1905	6.33e-76	236.0	COG1794@1|root,COG1794@2|Bacteria,1TR3U@1239|Firmicutes,4H4SU@909932|Negativicutes	909932|Negativicutes	G	Belongs to the aspartate glutamate racemases family	-	-	5.1.1.13	ko:K01779	ko00250,ko01054,map00250,map01054	-	R00491	RC00302	ko00000,ko00001,ko01000	-	-	-	Asp_Glu_race
NFNHFNFO_01907	33035.JPJF01000096_gene2092	5.33e-71	216.0	28NY7@1|root,2ZBVG@2|Bacteria,1V2J3@1239|Firmicutes,24G35@186801|Clostridia,3Y06T@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF2992)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2992
NFNHFNFO_01908	33035.JPJF01000096_gene2093	0.0	974.0	2DB9B@1|root,2Z7VY@2|Bacteria,1UHZN@1239|Firmicutes,24AP5@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
NFNHFNFO_01909	33035.JPJF01000096_gene2094	1.11e-206	572.0	COG1897@1|root,COG1897@2|Bacteria,1TQVR@1239|Firmicutes,247NP@186801|Clostridia,3XZIH@572511|Blautia	186801|Clostridia	E	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine	metAA	-	2.3.1.46	ko:K00651	ko00270,ko00920,ko01100,ko01110,ko01230,map00270,map00920,map01100,map01110,map01230	M00017	R01777	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS11970	HTS
NFNHFNFO_01910	33035.JPJF01000055_gene1664	0.0	1010.0	COG1502@1|root,COG1502@2|Bacteria,1TPKY@1239|Firmicutes,247UR@186801|Clostridia,3XZ8D@572511|Blautia	186801|Clostridia	I	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol	cls	-	-	ko:K06131	ko00564,ko01100,map00564,map01100	-	R07390	RC00017	ko00000,ko00001,ko01000	-	-	-	PLDc_2,PLDc_N
NFNHFNFO_01911	33035.JPJF01000055_gene1665	0.0	1201.0	COG0272@1|root,COG0272@2|Bacteria,1TPQ3@1239|Firmicutes,248AX@186801|Clostridia,3XZ8K@572511|Blautia	186801|Clostridia	L	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA	ligA	-	6.5.1.2	ko:K01972	ko03030,ko03410,ko03420,ko03430,map03030,map03410,map03420,map03430	-	R00382	RC00005	ko00000,ko00001,ko01000,ko03032,ko03400	-	-	-	BRCT,DNA_ligase_OB,DNA_ligase_ZBD,DNA_ligase_aden,HHH_2,HHH_5
NFNHFNFO_01912	33035.JPJF01000055_gene1666	4.35e-156	440.0	COG1187@1|root,COG1187@2|Bacteria,1TP68@1239|Firmicutes,248UG@186801|Clostridia,3XZ9V@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	rluF	-	5.4.99.21,5.4.99.22	ko:K06178,ko:K06182	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2,S4
NFNHFNFO_01913	33035.JPJF01000055_gene1667	3.17e-178	521.0	COG0726@1|root,COG5263@1|root,COG0726@2|Bacteria,COG5263@2|Bacteria,1V6DN@1239|Firmicutes,249SN@186801|Clostridia,3XZX1@572511|Blautia	186801|Clostridia	G	Polysaccharide deacetylase	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,ChW,Polysacc_deac_1
NFNHFNFO_01914	33035.JPJF01000055_gene1668	5.89e-189	528.0	COG3103@1|root,COG4991@2|Bacteria,1VD2T@1239|Firmicutes,24RYA@186801|Clostridia,3Y03B@572511|Blautia	186801|Clostridia	T	Bacterial SH3 domain	-	-	-	-	-	-	-	-	-	-	-	-	SH3_3
NFNHFNFO_01916	33035.JPJF01000055_gene1669	2.25e-188	526.0	28PM6@1|root,2ZCAA@2|Bacteria,1V4NT@1239|Firmicutes,24HIP@186801|Clostridia,3Y07Z@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01917	33035.JPJF01000055_gene1673	7.1e-130	369.0	COG0231@1|root,COG0231@2|Bacteria,1TR8P@1239|Firmicutes,249DV@186801|Clostridia,3XZPQ@572511|Blautia	186801|Clostridia	J	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase	efp	-	-	ko:K02356	-	-	-	-	ko00000,ko03012	-	-	-	EFP,EFP_N,Elong-fact-P_C
NFNHFNFO_01918	33035.JPJF01000055_gene1674	4.9e-116	332.0	COG2179@1|root,COG2179@2|Bacteria,1V6KM@1239|Firmicutes,24KK7@186801|Clostridia,3XZXE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yqeG	-	-	ko:K07015	-	-	-	-	ko00000	-	-	-	HAD_2,Hydrolase,Hydrolase_like,PGP_phosphatase
NFNHFNFO_01919	33035.JPJF01000055_gene1675	0.0	885.0	COG0372@1|root,COG0372@2|Bacteria,1TPPS@1239|Firmicutes,24865@186801|Clostridia,3XYZV@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	-	-	2.3.3.1	ko:K01647	ko00020,ko00630,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00740	R00351	RC00004,RC00067	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Citrate_synt
NFNHFNFO_01920	33035.JPJF01000055_gene1676	2.54e-74	223.0	COG0640@1|root,COG0640@2|Bacteria,1VA6G@1239|Firmicutes,24JCN@186801|Clostridia,3Y0CQ@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K21903	-	-	-	-	ko00000,ko03000	-	-	-	HTH_5
NFNHFNFO_01921	33035.JPJF01000055_gene1677	0.0	1392.0	COG0550@1|root,COG0551@1|root,COG0550@2|Bacteria,COG0551@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,3XYQH@572511|Blautia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	topB	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim
NFNHFNFO_01922	33035.JPJF01000055_gene1678	5.57e-225	622.0	COG2876@1|root,COG2876@2|Bacteria,1TP61@1239|Firmicutes,24812@186801|Clostridia,3XZMW@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	aroF	-	2.5.1.54	ko:K03856	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01826	RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	DAHP_synth_1
NFNHFNFO_01924	33035.JPJF01000055_gene1679	0.0	1108.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XZ2D@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFNHFNFO_01925	33035.JPJF01000055_gene1680	0.0	1272.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XYTY@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFNHFNFO_01926	33035.JPJF01000055_gene1681	4.09e-88	260.0	COG1846@1|root,COG1846@2|Bacteria,1VFS1@1239|Firmicutes,24QXV@186801|Clostridia,3Y0D8@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NFNHFNFO_01928	33035.JPJF01000055_gene1683	7.12e-310	847.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3XYXR@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_01929	33035.JPJF01000055_gene1684	2.38e-183	513.0	COG0697@1|root,COG0697@2|Bacteria,1TRKD@1239|Firmicutes,248I1@186801|Clostridia,3XYIR@572511|Blautia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_01930	33035.JPJF01000055_gene1685	2.31e-298	813.0	COG0436@1|root,COG0436@2|Bacteria,1TP0J@1239|Firmicutes,247NQ@186801|Clostridia,3XYYS@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	2.6.1.2,2.6.1.66	ko:K14260	ko00220,ko00250,ko00290,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00290,map01100,map01110,map01130,map01210,map01230	-	R00258,R01215	RC00006,RC00008,RC00036	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2,HTH_3
NFNHFNFO_01931	33035.JPJF01000055_gene1686	2.23e-149	422.0	COG4608@1|root,COG4608@2|Bacteria,1V2IG@1239|Firmicutes,24GEF@186801|Clostridia	186801|Clostridia	E	ATPases associated with a variety of cellular activities	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
NFNHFNFO_01932	33035.JPJF01000055_gene1687	8.29e-170	477.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3XZ1P@572511|Blautia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K02031,ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NFNHFNFO_01933	33035.JPJF01000055_gene1688	9.37e-168	471.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia	186801|Clostridia	P	ABC-type dipeptide oligopeptide nickel transport	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NFNHFNFO_01934	33035.JPJF01000055_gene1689	3.29e-189	528.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02033,ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
NFNHFNFO_01935	33035.JPJF01000055_gene1690	0.0	995.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia	186801|Clostridia	E	Family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NFNHFNFO_01936	33035.JPJF01000055_gene1691	1.53e-102	296.0	COG1327@1|root,COG1327@2|Bacteria,1V3JA@1239|Firmicutes,24HFT@186801|Clostridia,3XZYK@572511|Blautia	186801|Clostridia	K	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes	nrdR	-	-	ko:K07738	-	-	-	-	ko00000,ko03000	-	-	-	ATP-cone
NFNHFNFO_01937	33035.JPJF01000055_gene1692	6.33e-148	419.0	COG1244@1|root,COG1244@2|Bacteria,1UZ5M@1239|Firmicutes,24AIM@186801|Clostridia,3Y1MH@572511|Blautia	186801|Clostridia	S	Elongator protein 3, MiaB family, Radical SAM	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01938	33035.JPJF01000055_gene1693	5.39e-154	435.0	COG1738@1|root,COG1738@2|Bacteria,1TSAY@1239|Firmicutes,24EFG@186801|Clostridia	186801|Clostridia	S	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage	-	-	-	ko:K09125	-	-	-	-	ko00000	-	-	-	Vut_1
NFNHFNFO_01939	33035.JPJF01000055_gene1694	9.17e-223	617.0	COG1363@1|root,COG1363@2|Bacteria,1TQ86@1239|Firmicutes,25CDF@186801|Clostridia,3XYZU@572511|Blautia	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
NFNHFNFO_01940	33035.JPJF01000055_gene1695	4.45e-152	434.0	COG0454@1|root,COG0454@2|Bacteria,1V5SQ@1239|Firmicutes,24BQ5@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_01941	33035.JPJF01000055_gene1696	3.45e-118	338.0	299ND@1|root,2ZWQQ@2|Bacteria,1UZ92@1239|Firmicutes,24KDA@186801|Clostridia	186801|Clostridia	S	L-2-amino-thiazoline-4-carboxylic acid hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	ATC_hydrolase
NFNHFNFO_01942	33035.JPJF01000055_gene1697	2.67e-48	157.0	COG0537@1|root,COG0537@2|Bacteria,1VCZW@1239|Firmicutes	1239|Firmicutes	FG	HIT domain	-	-	3.6.1.17	ko:K01518	ko00230,ko00240,map00230,map00240	-	R00184,R00969,R01232,R02805	RC00002	ko00000,ko00001,ko01000	-	-	-	HIT
NFNHFNFO_01943	1121115.AXVN01000038_gene3334	1.36e-180	522.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V2J2@1239|Firmicutes,24CQK@186801|Clostridia,3Y1VC@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
NFNHFNFO_01944	457412.RSAG_02299	1.48e-242	689.0	COG2972@1|root,COG2972@2|Bacteria,1UZWA@1239|Firmicutes,24EGG@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
NFNHFNFO_01945	457412.RSAG_02298	1.14e-161	457.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia,3WJF8@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_01946	1121115.AXVN01000038_gene3331	2.55e-181	508.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AHK@186801|Clostridia,3XZH7@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_01947	457412.RSAG_02296	7.03e-240	667.0	COG1653@1|root,COG1653@2|Bacteria	2|Bacteria	G	carbohydrate transport	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_01948	457412.RSAG_02295	1.36e-266	731.0	COG0673@1|root,COG0673@2|Bacteria,1V0MQ@1239|Firmicutes,24CZ7@186801|Clostridia,3WMEG@541000|Ruminococcaceae	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NFNHFNFO_01949	33035.JPJF01000055_gene1699	2.77e-175	489.0	COG1191@1|root,COG1191@2|Bacteria,1TPDD@1239|Firmicutes,24A1H@186801|Clostridia,3XZ0B@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigG	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r3,Sigma70_r4
NFNHFNFO_01950	33035.JPJF01000055_gene1700	0.0	1241.0	COG0441@1|root,COG0441@2|Bacteria,1TP78@1239|Firmicutes,248CH@186801|Clostridia,3XYSJ@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	thrS	-	6.1.1.3	ko:K01868	ko00970,map00970	M00359,M00360	R03663	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,TGS,tRNA-synt_2b,tRNA_SAD
NFNHFNFO_01951	33035.JPJF01000055_gene1701	1.91e-174	489.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3XZFP@572511|Blautia	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
NFNHFNFO_01952	33035.JPJF01000055_gene1702	0.0	1004.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia,3Y0TG@572511|Blautia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminal domain	-	-	3.2.1.55	ko:K01209	ko00520,map00520	-	R01762	-	ko00000,ko00001,ko01000	-	GH51	-	Alpha-L-AF_C
NFNHFNFO_01953	33035.JPJF01000055_gene1703	0.0	945.0	2AJ90@1|root,319TX@2|Bacteria,1V137@1239|Firmicutes,24BHQ@186801|Clostridia	186801|Clostridia	S	Glucosyl transferase GtrII	-	-	-	-	-	-	-	-	-	-	-	-	Glucos_trans_II
NFNHFNFO_01954	537007.BLAHAN_06683	9.36e-44	143.0	COG1873@1|root,COG1873@2|Bacteria,1VEMT@1239|Firmicutes,25P5S@186801|Clostridia,3Y0IV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PRC
NFNHFNFO_01955	33035.JPJF01000002_gene2468	4.36e-240	660.0	COG0524@1|root,COG0524@2|Bacteria,1TQ9Q@1239|Firmicutes,25B0T@186801|Clostridia,3XYRS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
NFNHFNFO_01956	33035.JPJF01000002_gene2469	2.77e-248	681.0	COG0524@1|root,COG0524@2|Bacteria,1TRRY@1239|Firmicutes,248Y3@186801|Clostridia,3XZNP@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.45	ko:K00874	ko00030,ko01100,ko01120,ko01200,map00030,map01100,map01120,map01200	M00061,M00308,M00631	R01541	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	PfkB
NFNHFNFO_01957	33035.JPJF01000002_gene2470	3.41e-143	404.0	COG0800@1|root,COG0800@2|Bacteria,1TS0F@1239|Firmicutes,248GA@186801|Clostridia,3XYI5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	eda	-	4.1.2.14,4.1.3.42	ko:K01625	ko00030,ko00630,ko01100,ko01120,ko01200,map00030,map00630,map01100,map01120,map01200	M00008,M00061,M00308,M00631	R00470,R05605	RC00307,RC00308,RC00435	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase
NFNHFNFO_01958	33035.JPJF01000002_gene2471	4.93e-165	463.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia,3XZSI@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
NFNHFNFO_01959	33035.JPJF01000002_gene2473	1.22e-167	469.0	COG1191@1|root,COG1191@2|Bacteria,1TP3T@1239|Firmicutes,24A4T@186801|Clostridia,3XZGI@572511|Blautia	186801|Clostridia	K	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released	sigE	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4
NFNHFNFO_01960	33035.JPJF01000002_gene2474	4.41e-189	527.0	29ECG@1|root,301AF@2|Bacteria,1UY4W@1239|Firmicutes,24HI3@186801|Clostridia,3Y05C@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	spoIIGA	-	-	ko:K06383	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_U4
NFNHFNFO_01961	33035.JPJF01000002_gene2475	1.35e-147	419.0	COG0710@1|root,COG0710@2|Bacteria,1TSPN@1239|Firmicutes,249EX@186801|Clostridia,3XZNE@572511|Blautia	186801|Clostridia	E	Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate	aroD	-	4.2.1.10	ko:K03785	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03084	RC00848	ko00000,ko00001,ko00002,ko01000	-	-	-	DHquinase_I,SKI
NFNHFNFO_01962	33035.JPJF01000002_gene2477	3.77e-145	415.0	COG0169@1|root,COG0169@2|Bacteria,1TQRY@1239|Firmicutes,2497S@186801|Clostridia,3XYQC@572511|Blautia	186801|Clostridia	E	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)	aroE	-	1.1.1.25	ko:K00014	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02413	RC00206	ko00000,ko00001,ko00002,ko01000	-	-	-	Shikimate_DH,Shikimate_dh_N
NFNHFNFO_01963	33035.JPJF01000002_gene2478	1.02e-186	529.0	2CB1E@1|root,32RSJ@2|Bacteria,1VAQ3@1239|Firmicutes,24GGP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_01964	33035.JPJF01000002_gene2479	4.83e-100	292.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3Y07M@572511|Blautia	186801|Clostridia	K	RNA polymerase sigma-70 factor, ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_01965	33035.JPJF01000002_gene2480	1.73e-108	313.0	COG0521@1|root,COG0521@2|Bacteria,1V3XM@1239|Firmicutes,24HG2@186801|Clostridia,3Y02X@572511|Blautia	186801|Clostridia	H	Probable molybdopterin binding domain	mog	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
NFNHFNFO_01966	33035.JPJF01000002_gene2481	8.36e-101	293.0	COG0315@1|root,COG0315@2|Bacteria,1V3J4@1239|Firmicutes,24H9F@186801|Clostridia,3Y01J@572511|Blautia	186801|Clostridia	H	Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP)	moaC	-	4.6.1.17	ko:K03637	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R11372	RC03425	ko00000,ko00001,ko01000	-	-	-	MoaC
NFNHFNFO_01967	33035.JPJF01000002_gene2482	1.27e-254	702.0	COG0206@1|root,COG0206@2|Bacteria,1TP6W@1239|Firmicutes,247Z5@186801|Clostridia,3XYK3@572511|Blautia	186801|Clostridia	D	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity	ftsZ	-	-	ko:K03531	ko04112,map04112	-	-	-	ko00000,ko00001,ko02048,ko03036,ko04812	-	-	-	FtsZ_C,Tubulin
NFNHFNFO_01968	33035.JPJF01000002_gene2483	1.96e-162	463.0	COG1589@1|root,COG1589@2|Bacteria,1V34X@1239|Firmicutes,248RF@186801|Clostridia,3XZP0@572511|Blautia	186801|Clostridia	M	COG1589 Cell division septal protein	-	-	-	ko:K03589	ko04112,map04112	-	-	-	ko00000,ko00001,ko03036	-	-	-	FtsQ,POTRA_1
NFNHFNFO_01969	33035.JPJF01000002_gene2484	1.46e-267	735.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3XYUE@572511|Blautia	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA2	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
NFNHFNFO_01970	33035.JPJF01000002_gene2485	1e-241	669.0	COG0772@1|root,COG0772@2|Bacteria,1TPT7@1239|Firmicutes,24894@186801|Clostridia,3XYGP@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score 10.00	ftsW	-	-	ko:K03588	ko04112,map04112	-	-	-	ko00000,ko00001,ko02000,ko03036	2.A.103.1	-	-	FTSW_RODA_SPOVE
NFNHFNFO_01971	33035.JPJF01000002_gene2486	2.07e-298	818.0	COG0771@1|root,COG0771@2|Bacteria,1TQ3P@1239|Firmicutes,248GS@186801|Clostridia,3XYZG@572511|Blautia	186801|Clostridia	M	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)	murD	-	6.3.2.9	ko:K01925	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R02783	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase_C,Mur_ligase_M
NFNHFNFO_01972	33035.JPJF01000002_gene2487	8.46e-217	600.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia,3XZ7U@572511|Blautia	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
NFNHFNFO_01973	33035.JPJF01000002_gene2488	0.0	1117.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3XYPN@572511|Blautia	186801|Clostridia	M	COG COG0768 Cell division protein FtsI penicillin-binding protein 2	spoVD	-	3.4.16.4	ko:K03587,ko:K08384	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011,ko03036	-	-	-	PASTA,PBP_dimer,Transpeptidase
NFNHFNFO_01974	33035.JPJF01000002_gene2489	0.0	1304.0	COG0768@1|root,COG0768@2|Bacteria,1TP93@1239|Firmicutes,248KB@186801|Clostridia,3XZK3@572511|Blautia	186801|Clostridia	M	Cell division protein FtsI penicillin-binding protein 2	-	-	-	ko:K08384	ko00550,map00550	-	-	-	ko00000,ko00001,ko01011	-	-	-	PBP_dimer,Transpeptidase
NFNHFNFO_01975	33035.JPJF01000002_gene2490	3e-103	299.0	2E3U8@1|root,32YRK@2|Bacteria,1VEYB@1239|Firmicutes,24QRX@186801|Clostridia,3Y079@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
NFNHFNFO_01976	33035.JPJF01000002_gene2491	8.54e-218	602.0	COG0275@1|root,COG0275@2|Bacteria,1TNZV@1239|Firmicutes,248B5@186801|Clostridia,3XYP8@572511|Blautia	186801|Clostridia	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
NFNHFNFO_01977	33035.JPJF01000002_gene2492	1.31e-100	292.0	COG2001@1|root,COG2001@2|Bacteria,1V3JD@1239|Firmicutes,24HB9@186801|Clostridia,3XZXK@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	mraZ	-	-	ko:K03925	-	-	-	-	ko00000	-	-	-	MraZ
NFNHFNFO_01979	33035.JPJF01000002_gene2494	2.92e-180	504.0	COG0682@1|root,COG0682@2|Bacteria,1TPAK@1239|Firmicutes,24APG@186801|Clostridia,3XYMQ@572511|Blautia	186801|Clostridia	M	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins	lgt	-	-	ko:K13292	-	-	-	-	ko00000,ko01000	-	-	-	LGT
NFNHFNFO_01980	33035.JPJF01000002_gene2495	1.06e-255	702.0	COG0012@1|root,COG0012@2|Bacteria,1TPRK@1239|Firmicutes,2482Z@186801|Clostridia,3XZ6D@572511|Blautia	186801|Clostridia	J	ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner	ychF	-	-	ko:K06942	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1,YchF-GTPase_C
NFNHFNFO_01981	33035.JPJF01000002_gene2496	3.52e-143	405.0	COG1564@1|root,COG1564@2|Bacteria,1VA0W@1239|Firmicutes,24NG6@186801|Clostridia,3Y05M@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	thiN	-	2.7.6.2	ko:K00949	ko00730,ko01100,map00730,map01100	-	R00619	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	TPK_B1_binding,TPK_catalytic
NFNHFNFO_01982	33035.JPJF01000002_gene2497	5.76e-141	400.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3XZY7@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	rpe	-	5.1.3.1	ko:K01783	ko00030,ko00040,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00040,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01529	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	Ribul_P_3_epim
NFNHFNFO_01983	33035.JPJF01000002_gene2498	4.62e-195	542.0	COG1162@1|root,COG1162@2|Bacteria,1TPSQ@1239|Firmicutes,248R5@186801|Clostridia,3XZER@572511|Blautia	186801|Clostridia	S	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit	rsgA	-	3.1.3.100	ko:K06949	ko00730,ko01100,map00730,map01100	-	R00615,R02135	RC00002,RC00017	ko00000,ko00001,ko01000,ko03009	-	-	-	RsgA_GTPase,RsgA_N
NFNHFNFO_01984	33035.JPJF01000002_gene2499	0.0	1219.0	COG0515@1|root,COG0515@2|Bacteria,1TP3F@1239|Firmicutes,2492G@186801|Clostridia,3XZC8@572511|Blautia	186801|Clostridia	KLT	Psort location CytoplasmicMembrane, score	prkC	-	2.7.11.1	ko:K12132	-	-	-	-	ko00000,ko01000,ko01001	-	-	-	PASTA,Pkinase
NFNHFNFO_01985	33035.JPJF01000002_gene2500	1.74e-168	471.0	COG0631@1|root,COG0631@2|Bacteria,1V6K5@1239|Firmicutes,24JD4@186801|Clostridia,3XYRV@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	stp	-	3.1.3.16	ko:K20074	-	-	-	-	ko00000,ko01000,ko01009	-	-	-	PP2C,PP2C_2
NFNHFNFO_01986	33035.JPJF01000002_gene2501	1.91e-238	657.0	COG0820@1|root,COG0820@2|Bacteria,1TPVF@1239|Firmicutes,248BC@186801|Clostridia,3XZJW@572511|Blautia	186801|Clostridia	J	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs	rlmN	-	2.1.1.192	ko:K06941	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Fer4_14,Radical_SAM
NFNHFNFO_01987	33035.JPJF01000002_gene2502	0.0	868.0	COG0144@1|root,COG0781@1|root,COG0144@2|Bacteria,COG0781@2|Bacteria,1TP3N@1239|Firmicutes,248CS@186801|Clostridia,3XZPF@572511|Blautia	186801|Clostridia	J	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA	sun	-	2.1.1.176	ko:K03500	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,NusB
NFNHFNFO_01988	33035.JPJF01000002_gene2503	3.45e-195	544.0	COG0223@1|root,COG0223@2|Bacteria,1TQ32@1239|Firmicutes,248ED@186801|Clostridia,3XYI1@572511|Blautia	186801|Clostridia	J	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus	fmt	-	2.1.2.9	ko:K00604	ko00670,ko00970,map00670,map00970	-	R03940	RC00026,RC00165	ko00000,ko00001,ko01000	-	-	-	Formyl_trans_C,Formyl_trans_N
NFNHFNFO_01989	33035.JPJF01000002_gene2504	2.89e-105	304.0	COG0242@1|root,COG0242@2|Bacteria,1V70B@1239|Firmicutes,24JET@186801|Clostridia,3Y03J@572511|Blautia	186801|Clostridia	J	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions	def	-	3.5.1.88	ko:K01462	-	-	-	-	ko00000,ko01000	-	-	-	Pep_deformylase
NFNHFNFO_01990	33035.JPJF01000002_gene2505	0.0	1384.0	COG1198@1|root,COG1198@2|Bacteria,1TNYB@1239|Firmicutes,248EI@186801|Clostridia,3XYQI@572511|Blautia	186801|Clostridia	L	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA	priA	-	-	ko:K04066	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,Helicase_C,ResIII
NFNHFNFO_01991	33035.JPJF01000002_gene2506	0.0	928.0	COG0769@1|root,COG0769@2|Bacteria,1TPQE@1239|Firmicutes,248Q4@186801|Clostridia,3XYZ0@572511|Blautia	186801|Clostridia	M	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan	murE	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NFNHFNFO_01992	33035.JPJF01000069_gene4192	2.42e-210	582.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,3XYK8@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NFNHFNFO_01993	33035.JPJF01000069_gene4193	1.94e-95	279.0	COG3610@1|root,COG3610@2|Bacteria,1V6P0@1239|Firmicutes,24R80@186801|Clostridia,3Y0UC@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ThrE_2
NFNHFNFO_01994	33035.JPJF01000069_gene4194	1.57e-166	468.0	COG2966@1|root,COG2966@2|Bacteria,1TSE8@1239|Firmicutes,24A25@186801|Clostridia,3Y0H6@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7,ThrE
NFNHFNFO_01995	33035.JPJF01000069_gene4195	0.0	881.0	COG2508@1|root,COG2508@2|Bacteria	2|Bacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
NFNHFNFO_01996	33035.JPJF01000069_gene4196	0.0	1289.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3XZ8B@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NFNHFNFO_01997	33035.JPJF01000069_gene4197	3.4e-196	545.0	COG1968@1|root,COG1968@2|Bacteria,1TPFA@1239|Firmicutes,249KK@186801|Clostridia,3XZFP@572511|Blautia	186801|Clostridia	V	Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin	uppP	-	3.6.1.27	ko:K06153	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	BacA
NFNHFNFO_01998	33035.JPJF01000069_gene4198	0.0	2027.0	COG0458@1|root,COG0458@2|Bacteria,1TPID@1239|Firmicutes,2498I@186801|Clostridia,3XYH9@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	carB	-	6.3.5.5	ko:K01955	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_L_D2,CPSase_L_D3,DAP_epimerase,MGS
NFNHFNFO_01999	33035.JPJF01000069_gene4199	3.32e-264	723.0	COG0505@1|root,COG0505@2|Bacteria,1TQ8N@1239|Firmicutes,247Q8@186801|Clostridia,3XYS9@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	carA	-	6.3.5.5	ko:K01956	ko00240,ko00250,ko01100,map00240,map00250,map01100	M00051	R00256,R00575,R01395,R10948,R10949	RC00002,RC00010,RC00043,RC02750,RC02798,RC03314	ko00000,ko00001,ko00002,ko01000	-	-	-	CPSase_sm_chain,GATase
NFNHFNFO_02001	33035.JPJF01000028_gene2796	0.0	1293.0	COG1653@1|root,COG1653@2|Bacteria,1TPM0@1239|Firmicutes,24ARZ@186801|Clostridia	186801|Clostridia	G	Right handed beta helix region	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,DUF1565
NFNHFNFO_02002	33035.JPJF01000028_gene2797	0.0	1516.0	COG2203@1|root,COG3850@1|root,COG5001@1|root,COG2203@2|Bacteria,COG3850@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3XZE8@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF
NFNHFNFO_02003	33035.JPJF01000028_gene2798	6.16e-154	436.0	28K3V@1|root,2Z9SY@2|Bacteria,1V0NZ@1239|Firmicutes,24EEF@186801|Clostridia	186801|Clostridia	S	EcsC protein family	-	-	-	-	-	-	-	-	-	-	-	-	EcsC
NFNHFNFO_02004	33035.JPJF01000028_gene2799	0.0	1071.0	COG0210@1|root,COG0210@2|Bacteria,1TPSU@1239|Firmicutes,247RM@186801|Clostridia,3XZD3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	3.6.4.12	ko:K03657	ko03420,ko03430,map03420,map03430	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UvrD-helicase,UvrD_C
NFNHFNFO_02005	33035.JPJF01000028_gene2800	8.68e-234	667.0	COG1061@1|root,COG1205@1|root,COG1061@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes	1239|Firmicutes	L	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
NFNHFNFO_02006	33035.JPJF01000028_gene2800	7.34e-284	798.0	COG1061@1|root,COG1205@1|root,COG1061@2|Bacteria,COG1205@2|Bacteria,1TSPA@1239|Firmicutes	1239|Firmicutes	L	COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine	yprA	GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360	-	ko:K06877	-	-	-	-	ko00000	-	-	-	DEAD,DUF1998,Helicase_C
NFNHFNFO_02008	33035.JPJF01000028_gene2801	2.16e-109	318.0	COG1309@1|root,COG1309@2|Bacteria,1UUV1@1239|Firmicutes,2585K@186801|Clostridia,3Y1RA@572511|Blautia	186801|Clostridia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	WHG
NFNHFNFO_02009	33035.JPJF01000028_gene2802	8.41e-142	402.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3Y11K@572511|Blautia	186801|Clostridia	V	ABC transporter	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_02010	33035.JPJF01000028_gene2803	9.21e-227	630.0	28K0P@1|root,2Z9QJ@2|Bacteria,1TSN2@1239|Firmicutes,24YHY@186801|Clostridia	186801|Clostridia	P	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
NFNHFNFO_02011	33035.JPJF01000028_gene2804	2.35e-160	452.0	COG1237@1|root,COG1237@2|Bacteria,1UWI6@1239|Firmicutes,247K3@186801|Clostridia,3Y1XS@572511|Blautia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
NFNHFNFO_02012	33035.JPJF01000028_gene2805	1.6e-111	327.0	COG0789@1|root,COG0789@2|Bacteria,1UUV2@1239|Firmicutes,25M6G@186801|Clostridia,3Y269@572511|Blautia	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NFNHFNFO_02013	33035.JPJF01000028_gene2806	1.9e-97	285.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia	186801|Clostridia	Q	Methyltransferase, YaeB	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
NFNHFNFO_02014	33035.JPJF01000028_gene2807	1.01e-94	276.0	COG4154@1|root,COG4154@2|Bacteria,1V402@1239|Firmicutes,24FU7@186801|Clostridia,3XZZ7@572511|Blautia	186801|Clostridia	G	RbsD / FucU transport protein family	fucU	-	5.1.3.29	ko:K02431	-	-	R10764	RC00563	ko00000,ko01000	-	-	-	RbsD_FucU
NFNHFNFO_02015	33035.JPJF01000028_gene2808	3.4e-162	454.0	COG0235@1|root,COG0235@2|Bacteria,1TS5G@1239|Firmicutes,248NY@186801|Clostridia,3XZRB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fucA	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
NFNHFNFO_02016	33035.JPJF01000028_gene2809	0.0	933.0	COG1070@1|root,COG1070@2|Bacteria,1TP7Z@1239|Firmicutes,247ZU@186801|Clostridia,3XYXG@572511|Blautia	186801|Clostridia	G	FGGY family of carbohydrate kinases, C-terminal domain	rhaB	-	2.7.1.5,2.7.1.51	ko:K00848,ko:K00879	ko00040,ko00051,ko01120,map00040,map00051,map01120	-	R01902,R03014,R03241	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_02017	33035.JPJF01000028_gene2810	0.0	1200.0	COG2407@1|root,COG2407@2|Bacteria,1TQ5Q@1239|Firmicutes,248V0@186801|Clostridia,3XZ8N@572511|Blautia	186801|Clostridia	G	Converts the aldose L-fucose into the corresponding ketose L-fuculose	fucI	-	5.3.1.25,5.3.1.3	ko:K01818	ko00051,ko01120,map00051,map01120	-	R03163	RC00434	ko00000,ko00001,ko01000	-	-	-	Fucose_iso_C,Fucose_iso_N1,Fucose_iso_N2
NFNHFNFO_02018	33035.JPJF01000028_gene2811	3.98e-195	542.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V1UE@1239|Firmicutes,24AK4@186801|Clostridia,3XZ87@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NFNHFNFO_02019	33035.JPJF01000028_gene2812	0.0	930.0	COG1022@1|root,COG1022@2|Bacteria,1V0YG@1239|Firmicutes,25E9H@186801|Clostridia,3XZQH@572511|Blautia	186801|Clostridia	I	AMP-binding enzyme	-	-	6.2.1.3	ko:K01897	ko00061,ko00071,ko01100,ko01212,ko02024,ko03320,ko04146,ko04216,ko04714,ko04920,map00061,map00071,map01100,map01212,map02024,map03320,map04146,map04216,map04714,map04920	M00086	R01280	RC00004,RC00014	ko00000,ko00001,ko00002,ko01000,ko01004,ko04147	4.C.1.1	-	-	AMP-binding
NFNHFNFO_02020	33035.JPJF01000028_gene2813	2.77e-41	136.0	COG0236@1|root,COG0236@2|Bacteria,1VG07@1239|Firmicutes,25E9I@186801|Clostridia	186801|Clostridia	IQ	Phosphopantetheine attachment site	-	-	-	-	-	-	-	-	-	-	-	-	PP-binding
NFNHFNFO_02021	33035.JPJF01000028_gene2814	0.0	904.0	COG1020@1|root,COG1020@2|Bacteria,1TQP2@1239|Firmicutes,24AMK@186801|Clostridia,3Y0AJ@572511|Blautia	186801|Clostridia	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
NFNHFNFO_02022	33035.JPJF01000028_gene2815	5.88e-233	642.0	COG1073@1|root,COG1073@2|Bacteria,1TQYU@1239|Firmicutes,249J1@186801|Clostridia,3Y086@572511|Blautia	186801|Clostridia	S	Prolyl oligopeptidase family	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	FSH1,Hydrolase_4,Peptidase_S9
NFNHFNFO_02023	33035.JPJF01000028_gene2816	3.9e-67	207.0	2DWDV@1|root,32V1D@2|Bacteria,1VAUV@1239|Firmicutes,24NQH@186801|Clostridia	186801|Clostridia	S	SCP-2 sterol transfer family	-	-	-	-	-	-	-	-	-	-	-	-	SCP2
NFNHFNFO_02024	33035.JPJF01000028_gene2817	1.66e-126	361.0	COG1309@1|root,COG1309@2|Bacteria,1V09H@1239|Firmicutes,25B1M@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_02025	33035.JPJF01000028_gene2818	5.75e-135	389.0	COG0500@1|root,COG2226@2|Bacteria,1TQEA@1239|Firmicutes,24HII@186801|Clostridia	186801|Clostridia	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
NFNHFNFO_02026	33035.JPJF01000028_gene2819	0.0	869.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3XZU5@572511|Blautia	186801|Clostridia	G	COG COG2211 Na melibiose symporter and related transporters	gph	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_02027	33035.JPJF01000028_gene2820	2.79e-181	505.0	COG3622@1|root,COG3622@2|Bacteria,1TRQV@1239|Firmicutes,24AGD@186801|Clostridia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NFNHFNFO_02028	33035.JPJF01000028_gene2821	2.7e-233	643.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,24B6F@186801|Clostridia	186801|Clostridia	E	Oxidoreductase NAD-binding domain protein	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	Cupin_5,GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_02030	33035.JPJF01000028_gene2822	1.92e-233	644.0	COG1879@1|root,COG1879@2|Bacteria,1UIZ0@1239|Firmicutes,24E8M@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_4
NFNHFNFO_02031	33035.JPJF01000001_gene2575	1.09e-292	802.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia,3XZEB@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_02032	1280698.AUJS01000054_gene1473	0.0	1159.0	COG4409@1|root,COG4409@2|Bacteria,1TQRX@1239|Firmicutes,247TP@186801|Clostridia	186801|Clostridia	G	Psort location Cellwall, score	-	-	3.2.1.18	ko:K01186	ko00511,ko00600,ko04142,map00511,map00600,map04142	-	R04018	RC00028,RC00077	ko00000,ko00001,ko01000,ko02042	-	GH33	-	BNR_2,FIVAR,Laminin_G_3,Lipase_GDSL_2,Sialidase
NFNHFNFO_02033	33035.JPJF01000001_gene2574	6.07e-279	761.0	COG0673@1|root,COG0673@2|Bacteria,1TSPV@1239|Firmicutes,24DUU@186801|Clostridia,3Y29S@572511|Blautia	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_02034	33035.JPJF01000001_gene2573	2.74e-188	524.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia,3XZGR@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_02035	33035.JPJF01000001_gene2572	9.41e-201	557.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AHK@186801|Clostridia,3XZH7@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_02036	33035.JPJF01000001_gene2571	0.0	888.0	COG1653@1|root,COG1653@2|Bacteria,1UG52@1239|Firmicutes,24CJR@186801|Clostridia,3XZR7@572511|Blautia	186801|Clostridia	G	ABC transporter periplasmic binding protein YcjN precursor	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02037	33035.JPJF01000001_gene2570	7.5e-202	559.0	COG2207@1|root,COG2207@2|Bacteria,1U46S@1239|Firmicutes,24CVZ@186801|Clostridia,3XZY9@572511|Blautia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_02038	33035.JPJF01000001_gene2569	6.45e-100	290.0	COG2731@1|root,COG2731@2|Bacteria,1U3YR@1239|Firmicutes,24MGA@186801|Clostridia,3Y0TZ@572511|Blautia	186801|Clostridia	G	COG COG2731 Beta-galactosidase, beta subunit	-	-	-	-	-	-	-	-	-	-	-	-	DUF386
NFNHFNFO_02039	33035.JPJF01000001_gene2568	1.1e-165	463.0	COG2755@1|root,COG2755@2|Bacteria,1VCTB@1239|Firmicutes,24GZV@186801|Clostridia,3Y1E4@572511|Blautia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NFNHFNFO_02040	33035.JPJF01000001_gene2567	6.28e-250	686.0	28H6R@1|root,2Z7J3@2|Bacteria,1TQ2I@1239|Firmicutes,247QF@186801|Clostridia,3XZQV@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02041	33035.JPJF01000001_gene2566	5.78e-74	221.0	COG0375@1|root,COG0375@2|Bacteria,1V8EK@1239|Firmicutes,25CVT@186801|Clostridia	186801|Clostridia	S	Hydrogenase nickel insertion protein HypA	-	-	-	ko:K04651	-	-	-	-	ko00000,ko03110	-	-	-	HypA
NFNHFNFO_02042	33035.JPJF01000001_gene2565	0.0	1754.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3XZ32@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_20,Pyr_redox_2
NFNHFNFO_02043	33035.JPJF01000001_gene2564	1.17e-145	412.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,3XZ4U@572511|Blautia	186801|Clostridia	KO	UreA amidohydrolase (urease) regulatory and maturation protein UreG	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
NFNHFNFO_02044	33035.JPJF01000001_gene2563	3.76e-242	672.0	COG0642@1|root,COG2205@2|Bacteria,1TRC1@1239|Firmicutes,249XJ@186801|Clostridia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_02045	33035.JPJF01000001_gene2562	4.88e-139	395.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,3XYGU@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_02046	33035.JPJF01000001_gene2561	3.26e-166	466.0	COG1136@1|root,COG1136@2|Bacteria,1TQU8@1239|Firmicutes,24AM8@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_02047	33035.JPJF01000001_gene2560	0.0	1258.0	COG0577@1|root,COG0577@2|Bacteria,1TQ3S@1239|Firmicutes,248TI@186801|Clostridia	186801|Clostridia	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NFNHFNFO_02048	33035.JPJF01000001_gene2556	1.67e-51	163.0	COG5566@1|root,COG5566@2|Bacteria,1VEZS@1239|Firmicutes,24QVB@186801|Clostridia	186801|Clostridia	S	COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Mor
NFNHFNFO_02049	33035.JPJF01000001_gene2555	6.06e-106	309.0	COG4332@1|root,COG4332@2|Bacteria,1VBBZ@1239|Firmicutes,24H5E@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1062)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1062
NFNHFNFO_02050	1301100.HG529292_gene5164	4.05e-161	471.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,36FFK@31979|Clostridiaceae	186801|Clostridia	C	Na H antiporter	-	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
NFNHFNFO_02051	457415.HMPREF1006_01927	6.9e-31	124.0	COG1319@1|root,COG1319@2|Bacteria,3TBFW@508458|Synergistetes	508458|Synergistetes	C	PFAM FAD binding domain in molybdopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
NFNHFNFO_02052	1378168.N510_01976	9.03e-69	212.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes	1239|Firmicutes	C	Aerobic-type carbon monoxide dehydrogenase small subunit CoxS	cutS	-	1.17.1.5,1.2.5.3	ko:K03518,ko:K20446	ko00760,ko01120,map00760,map01120	-	R01720,R11168	RC00589,RC02800	ko00000,ko00001,ko01000	-	-	-	Fer2,Fer2_2
NFNHFNFO_02053	1519439.JPJG01000091_gene628	4.41e-219	640.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,2N87A@216572|Oscillospiraceae	186801|Clostridia	C	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain	-	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
NFNHFNFO_02054	865861.AZSU01000002_gene2717	1.86e-163	516.0	COG0457@1|root,COG1672@1|root,COG3629@1|root,COG0457@2|Bacteria,COG1672@2|Bacteria,COG3629@2|Bacteria,1TR6V@1239|Firmicutes,24AA2@186801|Clostridia,36DWM@31979|Clostridiaceae	186801|Clostridia	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
NFNHFNFO_02055	33035.JPJF01000001_gene2553	3.24e-238	659.0	COG1929@1|root,COG1929@2|Bacteria,1TPSI@1239|Firmicutes,249SH@186801|Clostridia,3XZPW@572511|Blautia	186801|Clostridia	G	Belongs to the glycerate kinase type-1 family	glxK	-	2.7.1.165	ko:K00865	ko00260,ko00561,ko00630,ko01100,ko01120,ko01130,map00260,map00561,map00630,map01100,map01120,map01130	-	R08572	RC00002,RC00428	ko00000,ko00001,ko01000	-	-	-	Gly_kinase
NFNHFNFO_02056	33035.JPJF01000001_gene2552	1.49e-221	615.0	COG3835@1|root,COG3835@2|Bacteria,1TTCF@1239|Firmicutes,24CMJ@186801|Clostridia,3Y0S2@572511|Blautia	186801|Clostridia	KT	Putative sugar diacid recognition	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	Diacid_rec,HTH_30
NFNHFNFO_02057	33035.JPJF01000001_gene2551	1.81e-138	394.0	COG1011@1|root,COG1011@2|Bacteria,1V7T4@1239|Firmicutes,25ISP@186801|Clostridia,3Y1UM@572511|Blautia	186801|Clostridia	S	HAD-hyrolase-like	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02058	33035.JPJF01000001_gene2550	3.81e-143	408.0	COG2768@1|root,COG2768@2|Bacteria,1V2K1@1239|Firmicutes,24FX2@186801|Clostridia,3Y284@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_9
NFNHFNFO_02059	33035.JPJF01000001_gene2549	3.55e-77	231.0	COG0640@1|root,COG0640@2|Bacteria,1V6Z2@1239|Firmicutes,24JUM@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, ArsR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
NFNHFNFO_02060	33035.JPJF01000001_gene2548	0.0	1483.0	COG0209@1|root,COG0209@2|Bacteria,1TPFH@1239|Firmicutes,249EN@186801|Clostridia,3Y12B@572511|Blautia	186801|Clostridia	F	Ribonucleotide reductase, barrel domain	-	-	1.17.4.1	ko:K00525	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R02017,R02018,R02019,R02024	RC00613	ko00000,ko00001,ko00002,ko01000,ko03400	-	-	-	ATP-cone,Ribonuc_red_lgC
NFNHFNFO_02061	33035.JPJF01000001_gene2547	9.15e-197	547.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,3XZEN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_02062	33035.JPJF01000001_gene2546	5.35e-175	489.0	COG0627@1|root,COG0627@2|Bacteria,1TPA9@1239|Firmicutes,24F6M@186801|Clostridia,3Y103@572511|Blautia	186801|Clostridia	S	Putative esterase	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
NFNHFNFO_02063	33035.JPJF01000001_gene2545	1.04e-40	144.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,248X0@186801|Clostridia,3Y14V@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02064	33035.JPJF01000001_gene2545	2.71e-211	590.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,248X0@186801|Clostridia,3Y14V@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02065	33035.JPJF01000001_gene2544	0.0	1155.0	COG0577@1|root,COG4591@1|root,COG0577@2|Bacteria,COG4591@2|Bacteria,1TQ8P@1239|Firmicutes,25E38@186801|Clostridia,3XZ2P@572511|Blautia	186801|Clostridia	MV	COG COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NFNHFNFO_02066	33035.JPJF01000001_gene2543	3.01e-151	426.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3XYM9@572511|Blautia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_02067	33035.JPJF01000001_gene2541	6.97e-15	71.6	COG0745@1|root,COG0745@2|Bacteria,1TQRT@1239|Firmicutes,24FGF@186801|Clostridia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_02068	33035.JPJF01000001_gene2534	4.65e-273	752.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3XZ7G@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_02069	33035.JPJF01000001_gene2533	4.99e-136	386.0	COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,249KF@186801|Clostridia,3XZYR@572511|Blautia	186801|Clostridia	S	Maltose acetyltransferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
NFNHFNFO_02070	33035.JPJF01000001_gene2532	3.16e-194	541.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZED@1239|Firmicutes,2490G@186801|Clostridia,3Y1IP@572511|Blautia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
NFNHFNFO_02071	411902.CLOBOL_05137	0.0	1640.0	COG0642@1|root,COG2202@1|root,COG2202@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,21Z6D@1506553|Lachnoclostridium	186801|Clostridia	T	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg,SnoaL_3
NFNHFNFO_02072	33035.JPJF01000001_gene2531	6.78e-297	816.0	COG0513@1|root,COG0513@2|Bacteria,1TPAP@1239|Firmicutes,247IT@186801|Clostridia	186801|Clostridia	L	Belongs to the DEAD box helicase family	dbpA	-	3.6.4.13	ko:K05592	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03009,ko03019	-	-	-	DEAD,DbpA,Helicase_C
NFNHFNFO_02074	33035.JPJF01000001_gene2530	6.36e-292	801.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2,MFS_3
NFNHFNFO_02075	33035.JPJF01000001_gene2529	1.64e-253	695.0	COG0407@1|root,COG0407@2|Bacteria,1VRN3@1239|Firmicutes,24Z8U@186801|Clostridia	186801|Clostridia	H	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02076	33035.JPJF01000001_gene2528	9.02e-300	822.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3XZ7Z@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_02077	457421.CBFG_00792	9e-91	268.0	COG0703@1|root,COG0703@2|Bacteria,1V1Z4@1239|Firmicutes,25E3E@186801|Clostridia,26B10@186813|unclassified Clostridiales	186801|Clostridia	E	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
NFNHFNFO_02078	1232453.BAIF02000053_gene906	4.29e-51	164.0	COG4430@1|root,COG4430@2|Bacteria,1VA6D@1239|Firmicutes,24N9F@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
NFNHFNFO_02079	658086.HMPREF0994_01829	5.55e-131	378.0	COG0789@1|root,COG0789@2|Bacteria,1VV2K@1239|Firmicutes,24AQK@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR,MerR_1
NFNHFNFO_02080	33035.JPJF01000013_gene4723	2.17e-129	381.0	28NJG@1|root,33CS1@2|Bacteria,1VKJX@1239|Firmicutes,24UHP@186801|Clostridia	186801|Clostridia	-	-	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase_2
NFNHFNFO_02081	1123075.AUDP01000003_gene527	1.76e-74	227.0	2BBZW@1|root,325IG@2|Bacteria,1URJM@1239|Firmicutes,259FU@186801|Clostridia,3WQ3I@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02083	1123075.AUDP01000003_gene529	3.57e-64	201.0	2C6ZI@1|root,32VIE@2|Bacteria,1VBAJ@1239|Firmicutes,24Q9Q@186801|Clostridia,3WQB0@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02085	33035.JPJF01000013_gene4722	1.86e-109	315.0	COG0244@1|root,COG0244@2|Bacteria,1V3JJ@1239|Firmicutes,24G9R@186801|Clostridia,3XZVD@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors	rplJ	-	-	ko:K02864	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L10
NFNHFNFO_02086	33035.JPJF01000013_gene4721	2.14e-63	196.0	COG0222@1|root,COG0222@2|Bacteria,1V6EI@1239|Firmicutes,24JAC@186801|Clostridia,3XZZA@572511|Blautia	186801|Clostridia	J	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation	rplL	-	-	ko:K02935	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L12,Ribosomal_L12_N
NFNHFNFO_02088	1461580.CCAS010000023_gene2409	1.52e-63	211.0	COG3039@1|root,COG3039@2|Bacteria,1TPFS@1239|Firmicutes,4HD09@91061|Bacilli,1ZEKY@1386|Bacillus	91061|Bacilli	L	COG3039 Transposase and inactivated derivatives, IS5 family	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1,DDE_Tnp_1_6,DUF772
NFNHFNFO_02089	1469948.JPNB01000002_gene3650	7.17e-176	501.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,24ZCF@186801|Clostridia,36QX6@31979|Clostridiaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NFNHFNFO_02090	411468.CLOSCI_01809	1.49e-162	458.0	COG1830@1|root,COG1830@2|Bacteria,1TR4S@1239|Firmicutes,24CMB@186801|Clostridia,21ZQ4@1506553|Lachnoclostridium	186801|Clostridia	G	DeoC/LacD family aldolase	-	-	4.1.2.13	ko:K11645	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	DeoC
NFNHFNFO_02091	411468.CLOSCI_01808	1.05e-203	568.0	COG1063@1|root,COG1063@2|Bacteria,1UZ8R@1239|Firmicutes,248ZT@186801|Clostridia,222QS@1506553|Lachnoclostridium	186801|Clostridia	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_02092	411468.CLOSCI_01812	2.16e-182	523.0	COG1113@1|root,COG1113@2|Bacteria,1UHVM@1239|Firmicutes,25E4I@186801|Clostridia	186801|Clostridia	E	amino acid	-	-	-	ko:K03294	-	-	-	-	ko00000	2.A.3.2	-	-	AA_permease_2
NFNHFNFO_02093	411468.CLOSCI_01811	3.46e-104	311.0	COG0196@1|root,COG0196@2|Bacteria,1TPKS@1239|Firmicutes,2484A@186801|Clostridia,21Y3Z@1506553|Lachnoclostridium	186801|Clostridia	H	riboflavin biosynthesis protein	ribF	-	2.7.1.26,2.7.7.2	ko:K11753	ko00740,ko01100,ko01110,map00740,map01100,map01110	M00125	R00161,R00549	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_syn,Flavokinase
NFNHFNFO_02094	411468.CLOSCI_01807	6.37e-109	326.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,25D2S@186801|Clostridia,22195@1506553|Lachnoclostridium	186801|Clostridia	K	Putative sugar-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sugar-bind
NFNHFNFO_02095	397290.C810_02877	5.32e-07	51.2	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,27KKZ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase, Mutator family	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
NFNHFNFO_02097	411468.CLOSCI_01434	4.02e-108	321.0	COG1737@1|root,COG1737@2|Bacteria,1TR5E@1239|Firmicutes,247Z7@186801|Clostridia,21XE5@1506553|Lachnoclostridium	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NFNHFNFO_02098	397291.C804_01374	3.5e-160	456.0	COG4209@1|root,COG4209@2|Bacteria,1TP33@1239|Firmicutes,247UA@186801|Clostridia,27U35@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NFNHFNFO_02099	1226325.HMPREF1548_05578	1.49e-133	388.0	COG0395@1|root,COG0395@2|Bacteria,1TP14@1239|Firmicutes,2481Z@186801|Clostridia,36G3X@31979|Clostridiaceae	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K17320	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NFNHFNFO_02100	1226325.HMPREF1548_05579	7.42e-168	479.0	COG4409@1|root,COG4409@2|Bacteria,1UJYD@1239|Firmicutes,25FEG@186801|Clostridia	186801|Clostridia	G	BNR repeat-like domain	-	-	-	-	-	-	-	-	-	-	-	-	BNR_2
NFNHFNFO_02101	658086.HMPREF0994_01269	2.82e-235	666.0	COG1653@1|root,COG1653@2|Bacteria,1UD90@1239|Firmicutes,24Z7K@186801|Clostridia,27RCY@186928|unclassified Lachnospiraceae	186801|Clostridia	G	transport	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02102	33035.JPJF01000016_gene3984	9.59e-226	624.0	COG2755@1|root,COG2755@2|Bacteria,1VAM0@1239|Firmicutes,2502H@186801|Clostridia	186801|Clostridia	E	N-terminus of Esterase_SGNH_hydro-type	-	-	-	-	-	-	-	-	-	-	-	-	GxDLY,Lipase_GDSL_3
NFNHFNFO_02103	1256908.HMPREF0373_00032	5.87e-10	64.7	COG2801@1|root,COG2801@2|Bacteria,1TQH6@1239|Firmicutes,249ZV@186801|Clostridia,25VV0@186806|Eubacteriaceae	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_23,HTH_28,Mu-transpos_C,rve
NFNHFNFO_02104	1216932.CM240_0499	3.23e-83	249.0	COG1396@1|root,COG1396@2|Bacteria,1VA98@1239|Firmicutes,24A4S@186801|Clostridia,36M7R@31979|Clostridiaceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_02105	33035.JPJF01000013_gene4707	4.04e-252	696.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3XZ6G@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3,Thioredoxin
NFNHFNFO_02106	33035.JPJF01000013_gene4706	0.0	1235.0	COG0526@1|root,COG0526@2|Bacteria,1TRBZ@1239|Firmicutes,249GQ@186801|Clostridia	186801|Clostridia	CO	PFAM Arylsulfotransferase (ASST)	-	-	-	-	-	-	-	-	-	-	-	-	Arylsulfotran_2,Arylsulfotrans,Thioredoxin
NFNHFNFO_02107	33035.JPJF01000013_gene4705	3.95e-148	418.0	COG0664@1|root,COG0664@2|Bacteria,1V575@1239|Firmicutes,24H9V@186801|Clostridia	186801|Clostridia	K	Cyclic nucleotide-binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
NFNHFNFO_02108	33035.JPJF01000013_gene4704	0.0	2491.0	COG0085@1|root,COG0085@2|Bacteria,1TP96@1239|Firmicutes,247J1@186801|Clostridia,3XYKN@572511|Blautia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoB	-	2.7.7.6	ko:K03043	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb2_1,RNA_pol_Rpb2_2,RNA_pol_Rpb2_3,RNA_pol_Rpb2_45,RNA_pol_Rpb2_6,RNA_pol_Rpb2_7
NFNHFNFO_02109	33035.JPJF01000013_gene4703	0.0	2326.0	COG0086@1|root,COG0086@2|Bacteria,1TNYT@1239|Firmicutes,24925@186801|Clostridia,3XYSW@572511|Blautia	186801|Clostridia	K	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates	rpoC	-	2.7.7.6	ko:K03046	ko00230,ko00240,ko01100,ko03020,map00230,map00240,map01100,map03020	M00183	R00435,R00441,R00442,R00443	RC02795	br01611,ko00000,ko00001,ko00002,ko01000,ko03021,ko03400	-	-	-	RNA_pol_Rpb1_1,RNA_pol_Rpb1_2,RNA_pol_Rpb1_3,RNA_pol_Rpb1_4,RNA_pol_Rpb1_5
NFNHFNFO_02110	33035.JPJF01000013_gene4702	2.17e-257	711.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia,3Y10V@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
NFNHFNFO_02111	33035.JPJF01000013_gene4701	2.72e-88	259.0	COG0048@1|root,COG0048@2|Bacteria,1V1FJ@1239|Firmicutes,24FQT@186801|Clostridia,3XZTZ@572511|Blautia	186801|Clostridia	J	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit	rpsL	-	-	ko:K02950	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosom_S12_S23
NFNHFNFO_02112	33035.JPJF01000013_gene4700	6.65e-102	296.0	COG0049@1|root,COG0049@2|Bacteria,1V1GG@1239|Firmicutes,24FQN@186801|Clostridia,3XYYV@572511|Blautia	186801|Clostridia	J	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA	rpsG	-	-	ko:K02992	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S7
NFNHFNFO_02113	33035.JPJF01000013_gene4699	0.0	1360.0	COG0480@1|root,COG0480@2|Bacteria,1TPF9@1239|Firmicutes,247VN@186801|Clostridia,3XYNI@572511|Blautia	186801|Clostridia	J	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome	fusA	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
NFNHFNFO_02114	33035.JPJF01000013_gene4698	8.48e-285	778.0	COG0050@1|root,COG0050@2|Bacteria,1TPKC@1239|Firmicutes,2485I@186801|Clostridia,3XZPV@572511|Blautia	186801|Clostridia	J	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis	tuf	-	-	ko:K02358	-	-	-	-	ko00000,ko03012,ko03029,ko04147	-	-	-	GTP_EFTU,GTP_EFTU_D2,GTP_EFTU_D3
NFNHFNFO_02115	1235803.C825_04540	1.84e-112	345.0	COG4637@1|root,COG4637@2|Bacteria,4NYNT@976|Bacteroidetes	976|Bacteroidetes	S	AAA ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_21
NFNHFNFO_02116	457412.RSAG_01488	3e-109	316.0	COG1396@1|root,COG1396@2|Bacteria,1UZN9@1239|Firmicutes,24APP@186801|Clostridia,3WPRU@541000|Ruminococcaceae	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_02117	1256908.HMPREF0373_01971	2.25e-37	125.0	2E5UB@1|root,330IM@2|Bacteria,1VI5J@1239|Firmicutes,24RAY@186801|Clostridia,25XIV@186806|Eubacteriaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TrmB
NFNHFNFO_02118	457412.RSAG_01486	5.13e-244	671.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,3WHJS@541000|Ruminococcaceae	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NFNHFNFO_02119	1256908.HMPREF0373_01969	2.53e-31	109.0	2CHC1@1|root,343JX@2|Bacteria,1VZRM@1239|Firmicutes,2545Q@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02120	1256908.HMPREF0373_01967	9.06e-159	445.0	COG0358@1|root,COG0358@2|Bacteria,1UZ28@1239|Firmicutes,248N2@186801|Clostridia	186801|Clostridia	L	CHC2 zinc finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-CHC2
NFNHFNFO_02121	1256908.HMPREF0373_01966	0.0	881.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,25VCP@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	VirE
NFNHFNFO_02122	1256908.HMPREF0373_01965	1.85e-47	152.0	2DQEK@1|root,32UNY@2|Bacteria,1VCGS@1239|Firmicutes,24MR4@186801|Clostridia,25YZW@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF5348
NFNHFNFO_02123	742723.HMPREF9477_01323	3.13e-303	832.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,27K2X@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
NFNHFNFO_02124	742723.HMPREF9477_01322	4.36e-72	218.0	2C5R4@1|root,2ZBQ6@2|Bacteria,1V1T6@1239|Firmicutes,25CQN@186801|Clostridia,27M9Y@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Transposon-encoded protein TnpV	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NFNHFNFO_02126	580332.Slit_0084	1.64e-16	75.5	COG1396@1|root,COG1396@2|Bacteria,1N7QP@1224|Proteobacteria,2WHY7@28216|Betaproteobacteria	28216|Betaproteobacteria	K	SMART helix-turn-helix domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_31
NFNHFNFO_02127	748224.HMPREF9436_02634	4.3e-51	179.0	COG3344@1|root,COG3344@2|Bacteria,1V11M@1239|Firmicutes,24E12@186801|Clostridia,3WRYY@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
NFNHFNFO_02128	411469.EUBHAL_00500	8.62e-286	790.0	COG0827@1|root,COG0827@2|Bacteria,1UXY1@1239|Firmicutes,24B3U@186801|Clostridia,25Y8Q@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,N6_Mtase
NFNHFNFO_02129	411469.EUBHAL_00501	1.55e-186	522.0	COG0827@1|root,COG0827@2|Bacteria,1UZYA@1239|Firmicutes,24CNN@186801|Clostridia,25YA8@186806|Eubacteriaceae	186801|Clostridia	L	BsuBI PstI restriction endonuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BsuBI_PstI_RE
NFNHFNFO_02130	500632.CLONEX_00847	5.16e-37	137.0	2C0US@1|root,33PKC@2|Bacteria,1VRWH@1239|Firmicutes,24NWA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02131	537007.BLAHAN_04641	2.38e-101	312.0	COG1196@1|root,COG1196@2|Bacteria,1TSP6@1239|Firmicutes,24CG8@186801|Clostridia	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02132	33035.JPJF01000013_gene4697	3.65e-66	202.0	COG1708@1|root,COG1708@2|Bacteria,1VAYF@1239|Firmicutes,24PMJ@186801|Clostridia	186801|Clostridia	S	Nucleotidyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transf_2
NFNHFNFO_02133	33035.JPJF01000013_gene4696	8.71e-65	199.0	COG1895@1|root,COG1895@2|Bacteria,1VDFQ@1239|Firmicutes,24NA4@186801|Clostridia	186801|Clostridia	S	HEPN domain	-	-	-	-	-	-	-	-	-	-	-	-	HEPN
NFNHFNFO_02134	33035.JPJF01000013_gene4683	2.04e-265	731.0	COG0477@1|root,COG2814@2|Bacteria,1UZ7N@1239|Firmicutes,25NTE@186801|Clostridia,3Y26K@572511|Blautia	186801|Clostridia	EGP	MFS_1 like family	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1_like
NFNHFNFO_02135	33035.JPJF01000013_gene4682	4.59e-115	331.0	COG2191@1|root,COG2191@2|Bacteria,1UZ0V@1239|Firmicutes,24FX7@186801|Clostridia,3Y09I@572511|Blautia	186801|Clostridia	C	molybdenum containing formylmethanofuran dehydrogenase, subunit E K00199	-	-	1.2.7.12	ko:K11261	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00567	R03015,R08060,R11743	RC00197,RC00323	ko00000,ko00001,ko00002,ko01000	-	-	-	FmdE,zf-dskA_traR
NFNHFNFO_02136	33035.JPJF01000013_gene4681	0.0	1096.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,3XYKH@572511|Blautia	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_III,MutS_V,Smr
NFNHFNFO_02137	1105031.HMPREF1141_2137	2.15e-71	219.0	COG3153@1|root,COG3153@2|Bacteria,1V3PW@1239|Firmicutes,24ACS@186801|Clostridia,36J99@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_02138	658655.HMPREF0988_01376	3.96e-115	340.0	28JN4@1|root,2ZI55@2|Bacteria,1VT72@1239|Firmicutes,24AUX@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02139	33035.JPJF01000013_gene4676	1.22e-148	419.0	COG0745@1|root,COG0745@2|Bacteria,1TSNV@1239|Firmicutes,2493A@186801|Clostridia,3Y04C@572511|Blautia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_02140	33035.JPJF01000013_gene4675	1.64e-178	501.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_02141	33035.JPJF01000013_gene4674	1.79e-145	411.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3XZQT@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_02142	33035.JPJF01000013_gene4673	0.0	1347.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia,3Y1H2@572511|Blautia	186801|Clostridia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
NFNHFNFO_02143	33035.JPJF01000013_gene4672	1.3e-259	717.0	COG3290@1|root,COG3290@2|Bacteria,1UI03@1239|Firmicutes,25E8U@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NFNHFNFO_02144	33035.JPJF01000013_gene4671	4.58e-136	388.0	COG3279@1|root,COG3279@2|Bacteria,1UUUP@1239|Firmicutes,25B16@186801|Clostridia	186801|Clostridia	T	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NFNHFNFO_02145	33035.JPJF01000013_gene4670	2.85e-164	461.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia	186801|Clostridia	V	ABC-type antimicrobial peptide transport system, ATPase component	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_02146	33035.JPJF01000013_gene4669	0.0	1096.0	COG0577@1|root,COG0577@2|Bacteria,1TSMB@1239|Firmicutes,24ABI@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NFNHFNFO_02147	33035.JPJF01000013_gene4667	4.83e-108	311.0	COG1595@1|root,COG1595@2|Bacteria,1V8GV@1239|Firmicutes,24JEH@186801|Clostridia,3Y2C1@572511|Blautia	186801|Clostridia	K	Sigma-70 region 2	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_02148	33035.JPJF01000013_gene4666	1.5e-193	541.0	COG5660@1|root,COG5660@2|Bacteria,1VKXY@1239|Firmicutes,24UK9@186801|Clostridia,3Y0RV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
NFNHFNFO_02150	33035.JPJF01000013_gene4659	1.25e-128	366.0	COG2818@1|root,COG2818@2|Bacteria,1UZRT@1239|Firmicutes,25B15@186801|Clostridia	186801|Clostridia	L	Methyladenine glycosylase	tag	-	3.2.2.20	ko:K01246	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Adenine_glyco
NFNHFNFO_02151	33035.JPJF01000013_gene4654	2.08e-253	702.0	COG0642@1|root,COG2205@2|Bacteria,1UWJ3@1239|Firmicutes,25E8T@186801|Clostridia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_02152	33035.JPJF01000013_gene4653	2.82e-153	431.0	COG0745@1|root,COG0745@2|Bacteria,1UZIS@1239|Firmicutes,24CCE@186801|Clostridia,3XYX9@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_02153	33035.JPJF01000013_gene4652	0.0	1140.0	COG1653@1|root,COG1653@2|Bacteria,1V540@1239|Firmicutes,25B14@186801|Clostridia	186801|Clostridia	G	transport	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02154	33035.JPJF01000013_gene4651	3.12e-191	532.0	COG1175@1|root,COG1175@2|Bacteria,1TQTC@1239|Firmicutes,24AQX@186801|Clostridia,3Y0K9@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_02155	33035.JPJF01000013_gene4650	9.24e-185	515.0	COG0395@1|root,COG0395@2|Bacteria,1TS82@1239|Firmicutes,2488S@186801|Clostridia,3XYW1@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_02156	33035.JPJF01000013_gene4649	3.87e-184	531.0	COG0845@1|root,COG0845@2|Bacteria,1V7WB@1239|Firmicutes,24CBF@186801|Clostridia	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	-	-	-	-	-	-	-	-	-	HlyD_3
NFNHFNFO_02157	33035.JPJF01000013_gene4648	3.07e-176	500.0	2E1BR@1|root,32WRK@2|Bacteria,1V7RQ@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MacB_PCD
NFNHFNFO_02158	33035.JPJF01000013_gene4647	4.52e-101	298.0	COG0110@1|root,COG0110@2|Bacteria	2|Bacteria	S	O-acyltransferase activity	lacA	GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008374,GO:0008870,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0042802,GO:0044424,GO:0044464	2.3.1.18,2.3.1.79	ko:K00633,ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
NFNHFNFO_02159	33035.JPJF01000013_gene4646	1.36e-271	748.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3XZ7G@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_02160	33035.JPJF01000013_gene4645	5.28e-182	511.0	COG2207@1|root,COG2207@2|Bacteria,1VT0T@1239|Firmicutes,24YTA@186801|Clostridia,3Y0YN@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_02161	33035.JPJF01000013_gene4644	2.82e-27	100.0	2CDEN@1|root,2ZUAD@2|Bacteria,1W2UE@1239|Firmicutes,2569U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02162	33035.JPJF01000013_gene4643	2.15e-75	225.0	COG1695@1|root,COG1695@2|Bacteria,1VAKA@1239|Firmicutes,24MVF@186801|Clostridia,3Y1TV@572511|Blautia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
NFNHFNFO_02163	33035.JPJF01000013_gene4642	5.5e-218	610.0	COG0772@1|root,COG0772@2|Bacteria,1TRIP@1239|Firmicutes,258QF@186801|Clostridia,3Y1Z2@572511|Blautia	186801|Clostridia	D	Belongs to the SEDS family	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02165	33035.JPJF01000013_gene4639	1.09e-43	154.0	2C7NE@1|root,348SX@2|Bacteria,1VZZ3@1239|Firmicutes,254BH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02166	33035.JPJF01000016_gene4135	5e-275	752.0	COG0407@1|root,COG0407@2|Bacteria,1V4WM@1239|Firmicutes,24BVD@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
NFNHFNFO_02167	33035.JPJF01000016_gene4134	0.0	963.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3XZDA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_02168	33035.JPJF01000016_gene4133	3.03e-236	651.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,25E93@186801|Clostridia,3Y1HJ@572511|Blautia	186801|Clostridia	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NFNHFNFO_02169	33035.JPJF01000016_gene4132	1.18e-299	823.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3XYSC@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_02170	33035.JPJF01000016_gene4131	5.57e-269	743.0	COG1109@1|root,COG1109@2|Bacteria,1TS6S@1239|Firmicutes,2491F@186801|Clostridia	186801|Clostridia	G	Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II	manB	-	5.4.2.2,5.4.2.8	ko:K01840,ko:K15778	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NFNHFNFO_02171	33035.JPJF01000016_gene4130	1.04e-96	284.0	2BD3C@1|root,3320H@2|Bacteria,1VHD7@1239|Firmicutes,24S6N@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02172	33035.JPJF01000016_gene4129	1.38e-139	397.0	COG2819@1|root,COG2819@2|Bacteria,1V1TT@1239|Firmicutes,24GDE@186801|Clostridia,3Y0P9@572511|Blautia	186801|Clostridia	S	hydrolase of the alpha beta superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Esterase
NFNHFNFO_02173	33035.JPJF01000016_gene4128	7.32e-144	407.0	COG0727@1|root,COG0727@2|Bacteria,1TT6P@1239|Firmicutes,24BWS@186801|Clostridia,3XZVI@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
NFNHFNFO_02174	33035.JPJF01000016_gene4126	0.0	1377.0	COG1523@1|root,COG1523@2|Bacteria,1TP3M@1239|Firmicutes,2481P@186801|Clostridia,3XZ4C@572511|Blautia	186801|Clostridia	G	COG COG1523 Type II secretory pathway, pullulanase PulA and related glycosidases	glgX	-	3.2.1.68	ko:K01214	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R09995,R11261	-	ko00000,ko00001,ko00002,ko01000	-	CBM48,GH13	-	Alpha-amylase,CBM_48
NFNHFNFO_02175	33035.JPJF01000016_gene4125	8.9e-233	644.0	COG0727@1|root,COG0727@2|Bacteria,1TSB6@1239|Firmicutes,24AQ9@186801|Clostridia,3XYMM@572511|Blautia	186801|Clostridia	S	N-methylation of lysine residues in flagellin	fliU	-	-	ko:K18475	-	-	-	-	ko00000,ko01000,ko02035	-	-	-	CxxCxxCC
NFNHFNFO_02176	33035.JPJF01000016_gene4124	1.28e-201	561.0	COG0042@1|root,COG0042@2|Bacteria,1TRJM@1239|Firmicutes,247R5@186801|Clostridia,3XZ2T@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines	-	-	-	-	-	-	-	-	-	-	-	-	Dus
NFNHFNFO_02178	33035.JPJF01000016_gene4122	0.0	1066.0	COG2199@1|root,COG2199@2|Bacteria,1V8R1@1239|Firmicutes,24FNF@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,dCache_1
NFNHFNFO_02179	33035.JPJF01000016_gene4121	0.0	1157.0	COG4637@1|root,COG4637@2|Bacteria,1UZCB@1239|Firmicutes,248WE@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_15,AAA_21
NFNHFNFO_02180	33035.JPJF01000016_gene4120	6.82e-162	459.0	COG0564@1|root,COG0564@2|Bacteria,1W6ZU@1239|Firmicutes,24YS1@186801|Clostridia,3Y055@572511|Blautia	186801|Clostridia	J	RNA pseudouridylate synthase	-	-	-	-	-	-	-	-	-	-	-	-	PseudoU_synth_2
NFNHFNFO_02181	33035.JPJF01000016_gene4119	0.0	958.0	COG3835@1|root,COG3835@2|Bacteria,1TR5V@1239|Firmicutes,25E92@186801|Clostridia	186801|Clostridia	KT	Purine catabolism regulatory protein-like family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30,PucR
NFNHFNFO_02182	33035.JPJF01000016_gene4118	2.81e-255	701.0	COG3535@1|root,COG3535@2|Bacteria,1TR39@1239|Firmicutes,24A65@186801|Clostridia,3Y244@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF917)	-	-	-	ko:K09703	-	-	-	-	ko00000	-	-	-	DUF917
NFNHFNFO_02183	33035.JPJF01000016_gene4117	0.0	946.0	COG0145@1|root,COG0145@2|Bacteria,1TQVB@1239|Firmicutes,24AJ7@186801|Clostridia,3Y0KA@572511|Blautia	186801|Clostridia	EQ	Hydantoinase/oxoprolinase	-	-	-	-	-	-	-	-	-	-	-	-	Hydant_A_N,Hydantoinase_A
NFNHFNFO_02184	33035.JPJF01000016_gene4116	4.15e-177	497.0	COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,248CX@186801|Clostridia,3Y2EF@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_02185	33035.JPJF01000016_gene4115	1.93e-80	240.0	COG1846@1|root,COG1846@2|Bacteria,1TTKE@1239|Firmicutes,25MWQ@186801|Clostridia,3Y23H@572511|Blautia	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
NFNHFNFO_02186	33035.JPJF01000016_gene4114	0.0	1029.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247T8@186801|Clostridia,3XZEC@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFNHFNFO_02187	33035.JPJF01000016_gene4113	0.0	1198.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XZBH@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFNHFNFO_02188	33035.JPJF01000016_gene3845	3.35e-62	227.0	COG4219@1|root,COG4219@2|Bacteria,1TP3Z@1239|Firmicutes,24FVB@186801|Clostridia,3Y017@572511|Blautia	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	ko:K02172	ko01501,map01501	M00627	-	-	ko00000,ko00001,ko00002,ko01002,ko01504	-	-	-	DUF4097,DUF4825,DUF4829,Peptidase_M56
NFNHFNFO_02189	33035.JPJF01000016_gene4111	4.47e-63	193.0	COG3254@1|root,COG3254@2|Bacteria,1VA1C@1239|Firmicutes,24JG9@186801|Clostridia,3Y0GA@572511|Blautia	186801|Clostridia	G	Involved in the anomeric conversion of L-rhamnose	rhaM	-	5.1.3.32	ko:K03534	-	-	R10819	RC00563	ko00000,ko01000	-	-	-	rhaM
NFNHFNFO_02190	33035.JPJF01000016_gene4110	4.73e-57	179.0	COG4898@1|root,COG4898@2|Bacteria,1V6U6@1239|Firmicutes,24I63@186801|Clostridia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF2200
NFNHFNFO_02191	1123075.AUDP01000007_gene2792	2.56e-78	238.0	COG0431@1|root,COG0431@2|Bacteria,1V70S@1239|Firmicutes,24FJ8@186801|Clostridia,3WKB6@541000|Ruminococcaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
NFNHFNFO_02192	1123075.AUDP01000007_gene2792	1.09e-07	53.1	COG0431@1|root,COG0431@2|Bacteria,1V70S@1239|Firmicutes,24FJ8@186801|Clostridia,3WKB6@541000|Ruminococcaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_2
NFNHFNFO_02193	1123075.AUDP01000007_gene2791	6.43e-88	261.0	COG0655@1|root,COG0655@2|Bacteria,1V6U2@1239|Firmicutes,24GJC@186801|Clostridia,3WK5D@541000|Ruminococcaceae	186801|Clostridia	S	Alpha beta hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NFNHFNFO_02194	180332.JTGN01000007_gene3787	1.51e-80	244.0	COG1309@1|root,COG1309@2|Bacteria,1U9UE@1239|Firmicutes,24M4I@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
NFNHFNFO_02195	33035.JPJF01000016_gene4105	1.54e-307	839.0	COG2256@1|root,COG2256@2|Bacteria,1TPVV@1239|Firmicutes,247X2@186801|Clostridia,3XZ05@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	rarA	-	-	ko:K07478	-	-	-	-	ko00000	-	-	-	AAA,AAA_assoc_2,MgsA_C,RuvB_N
NFNHFNFO_02196	33035.JPJF01000016_gene4104	4.01e-44	143.0	29V17@1|root,30GEB@2|Bacteria,1UFV5@1239|Firmicutes,25MT2@186801|Clostridia,3Y0QI@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02197	33035.JPJF01000016_gene4103	1.63e-124	356.0	COG2135@1|root,COG2135@2|Bacteria,1TRRV@1239|Firmicutes,24GD7@186801|Clostridia,3XZ2G@572511|Blautia	186801|Clostridia	S	SOS response associated peptidase (SRAP)	-	-	-	-	-	-	-	-	-	-	-	-	SRAP
NFNHFNFO_02198	33035.JPJF01000016_gene4102	5.91e-281	770.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3XYYM@572511|Blautia	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
NFNHFNFO_02199	33035.JPJF01000016_gene4101	1.66e-76	229.0	2E99X@1|root,333HZ@2|Bacteria,1VFDA@1239|Firmicutes,24RP0@186801|Clostridia,3Y0PY@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02200	33035.JPJF01000016_gene4100	1.5e-185	516.0	COG2162@1|root,COG2162@2|Bacteria,1V6M1@1239|Firmicutes,24G0C@186801|Clostridia	186801|Clostridia	Q	N-acetyltransferase	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
NFNHFNFO_02201	33035.JPJF01000016_gene4099	2.02e-249	686.0	COG2006@1|root,COG2006@2|Bacteria,1TRYQ@1239|Firmicutes,24966@186801|Clostridia,3XZNX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF362
NFNHFNFO_02202	33035.JPJF01000016_gene4098	1.15e-234	645.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia,3Y1E6@572511|Blautia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_02203	33035.JPJF01000016_gene4097	2.81e-247	682.0	COG0477@1|root,COG2814@2|Bacteria,1W76W@1239|Firmicutes,25M5F@186801|Clostridia,3Y1X9@572511|Blautia	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NFNHFNFO_02204	33035.JPJF01000016_gene4096	0.0	913.0	COG2508@1|root,COG2508@2|Bacteria,1VTW2@1239|Firmicutes,24YNS@186801|Clostridia	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NFNHFNFO_02205	33035.JPJF01000016_gene4095	1.14e-156	442.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,3XYYY@572511|Blautia	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NFNHFNFO_02206	33035.JPJF01000016_gene4094	0.0	1449.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3XZ2A@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NFNHFNFO_02207	33035.JPJF01000016_gene4093	2.06e-78	233.0	COG1393@1|root,COG1393@2|Bacteria,1VA5Q@1239|Firmicutes,24JGY@186801|Clostridia,3Y05X@572511|Blautia	186801|Clostridia	P	Belongs to the ArsC family	-	-	1.20.4.1	ko:K00537	-	-	-	-	ko00000,ko01000	-	-	-	ArsC,Glutaredoxin
NFNHFNFO_02208	33035.JPJF01000016_gene4092	0.0	1055.0	COG2199@1|root,COG2606@1|root,COG2199@2|Bacteria,COG2606@2|Bacteria,1V3MU@1239|Firmicutes,24HH2@186801|Clostridia,3Y1PZ@572511|Blautia	186801|Clostridia	T	Aminoacyl-tRNA editing domain	EbsC	-	-	-	-	-	-	-	-	-	-	-	tRNA_edit
NFNHFNFO_02209	33035.JPJF01000016_gene4090	1.22e-165	466.0	COG2145@1|root,COG2145@2|Bacteria,1V1R6@1239|Firmicutes,248AC@186801|Clostridia,3XZZP@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)	thiM	-	2.7.1.50	ko:K00878	ko00730,ko01100,map00730,map01100	M00127	R04448	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	HK
NFNHFNFO_02210	33035.JPJF01000016_gene4089	9.38e-129	369.0	COG0352@1|root,COG0352@2|Bacteria,1V3ZR@1239|Firmicutes,24DG3@186801|Clostridia,3XZWG@572511|Blautia	186801|Clostridia	H	Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP)	thiE	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	TMP-TENI
NFNHFNFO_02211	33035.JPJF01000016_gene4088	1.38e-124	358.0	COG0637@1|root,COG0637@2|Bacteria,1VCK3@1239|Firmicutes,25B1D@186801|Clostridia	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
NFNHFNFO_02212	33035.JPJF01000016_gene4087	2.67e-170	478.0	COG0351@1|root,COG0351@2|Bacteria,1TQ4A@1239|Firmicutes,2483H@186801|Clostridia,3XYTK@572511|Blautia	186801|Clostridia	H	Phosphomethylpyrimidine kinase	thiD	-	2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7	ko:K00868,ko:K00941,ko:K14153	ko00730,ko00750,ko01100,map00730,map00750,map01100	M00127	R00174,R01909,R02493,R03223,R03471,R04509,R10712	RC00002,RC00017,RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	-	Phos_pyr_kin
NFNHFNFO_02213	33035.JPJF01000016_gene4086	0.0	1497.0	COG1882@1|root,COG1882@2|Bacteria,1TPTF@1239|Firmicutes,247YY@186801|Clostridia,3XZ2A@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	pflB	-	2.3.1.54	ko:K00656	ko00620,ko00640,ko00650,ko01100,ko01120,map00620,map00640,map00650,map01100,map01120	-	R00212,R06987	RC00004,RC01181,RC02742,RC02833	ko00000,ko00001,ko01000	-	-	-	Gly_radical,PFL-like
NFNHFNFO_02214	33035.JPJF01000016_gene4085	3.72e-144	408.0	COG1180@1|root,COG1180@2|Bacteria,1TPK2@1239|Firmicutes,247NA@186801|Clostridia,3XYYY@572511|Blautia	186801|Clostridia	C	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine	pflA	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Radical_SAM
NFNHFNFO_02215	33035.JPJF01000016_gene4084	1.07e-187	524.0	2C6CR@1|root,2Z7X4@2|Bacteria,1UY2Y@1239|Firmicutes,24EJP@186801|Clostridia,3XZW6@572511|Blautia	186801|Clostridia	S	Putative, 10TM heavy-metal exporter	-	-	-	ko:K07089	-	-	-	-	ko00000	-	-	-	ArsP_2
NFNHFNFO_02216	33035.JPJF01000016_gene4083	1.33e-119	343.0	2DIV4@1|root,30473@2|Bacteria,1V5EC@1239|Firmicutes,24IZE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02217	33035.JPJF01000016_gene4082	1.78e-42	138.0	COG1278@1|root,COG1278@2|Bacteria,1VEE0@1239|Firmicutes,24QJE@186801|Clostridia	186801|Clostridia	K	Cold shock protein	cspA	-	-	ko:K03704	-	-	-	-	ko00000,ko03000	-	-	-	CSD
NFNHFNFO_02218	1235793.C809_01506	2.71e-99	291.0	COG1514@1|root,COG1514@2|Bacteria,1VGSY@1239|Firmicutes,24ETC@186801|Clostridia,27TWE@186928|unclassified Lachnospiraceae	186801|Clostridia	J	2'-5' RNA ligase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	2_5_RNA_ligase2
NFNHFNFO_02219	397291.C804_03341	8.65e-27	99.0	28RSS@1|root,2ZE56@2|Bacteria,1W2HX@1239|Firmicutes,24UZT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02220	33035.JPJF01000016_gene4072	0.0	919.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3XYH4@572511|Blautia	186801|Clostridia	O	AAA domain (dynein-related subfamily)	-	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA
NFNHFNFO_02221	457415.HMPREF1006_02523	9.16e-47	167.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	BLUF,GGDEF,PAS_9
NFNHFNFO_02222	411474.COPEUT_00556	4.78e-25	94.7	COG3655@1|root,COG3655@2|Bacteria	2|Bacteria	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	DUF4384,HTH_26,HTH_3
NFNHFNFO_02223	33035.JPJF01000016_gene4052	0.0	1011.0	COG1474@1|root,COG3410@1|root,COG1474@2|Bacteria,COG3410@2|Bacteria,1TPQU@1239|Firmicutes,24BAG@186801|Clostridia,3Y0SY@572511|Blautia	186801|Clostridia	LO	Uncharacterized conserved protein (DUF2075)	-	-	-	ko:K09384	-	-	-	-	ko00000	-	-	-	DUF2075,GIY-YIG
NFNHFNFO_02224	33035.JPJF01000016_gene4051	1.59e-71	215.0	COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,24NYY@186801|Clostridia,3Y09V@572511|Blautia	186801|Clostridia	S	MazG-like family	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
NFNHFNFO_02225	478749.BRYFOR_09071	3.37e-90	266.0	COG3727@1|root,COG3727@2|Bacteria,1V3S8@1239|Firmicutes,24MYE@186801|Clostridia	186801|Clostridia	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
NFNHFNFO_02226	478749.BRYFOR_09070	3.81e-60	198.0	COG3066@1|root,COG3066@2|Bacteria,1TS3J@1239|Firmicutes,249BA@186801|Clostridia	186801|Clostridia	L	DNA mismatch repair	-	-	-	-	-	-	-	-	-	-	-	-	MutH
NFNHFNFO_02227	478749.BRYFOR_09070	3.79e-191	541.0	COG3066@1|root,COG3066@2|Bacteria,1TS3J@1239|Firmicutes,249BA@186801|Clostridia	186801|Clostridia	L	DNA mismatch repair	-	-	-	-	-	-	-	-	-	-	-	-	MutH
NFNHFNFO_02228	742765.HMPREF9457_02194	1.07e-269	745.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,27WI3@189330|Dorea	186801|Clostridia	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
NFNHFNFO_02229	888832.HMPREF9420_1692	4.46e-68	234.0	28IB4@1|root,2Z8DM@2|Bacteria	2|Bacteria	L	DNA mismatch repair enzyme MutH	-	-	-	-	-	-	-	-	-	-	-	-	MutH
NFNHFNFO_02230	1506994.JNLQ01000002_gene506	5.78e-259	733.0	COG3727@1|root,COG3727@2|Bacteria,1UFHM@1239|Firmicutes,24ERC@186801|Clostridia,4C0G6@830|Butyrivibrio	186801|Clostridia	L	T/G mismatch-specific endonuclease activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02231	1506994.JNLQ01000002_gene507	1.06e-128	374.0	2BZDU@1|root,2ZB95@2|Bacteria,1VCT5@1239|Firmicutes,24KN2@186801|Clostridia,4C1B9@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02232	1506994.JNLQ01000002_gene508	2.83e-105	311.0	28NAA@1|root,2ZBE4@2|Bacteria,1VDUD@1239|Firmicutes,25PWF@186801|Clostridia,4C1A4@830|Butyrivibrio	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02233	411462.DORLON_02919	2.8e-18	84.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,27WI3@189330|Dorea	186801|Clostridia	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
NFNHFNFO_02234	944564.HMPREF9200_0270	1.1e-96	309.0	COG3066@1|root,COG3066@2|Bacteria,1TS3J@1239|Firmicutes,4H789@909932|Negativicutes	909932|Negativicutes	L	DNA mismatch repair enzyme MutH	-	-	-	-	-	-	-	-	-	-	-	-	MutH
NFNHFNFO_02235	33035.JPJF01000016_gene4033	1.45e-107	310.0	COG0394@1|root,COG0394@2|Bacteria,1V6SG@1239|Firmicutes,24MMZ@186801|Clostridia,3Y08X@572511|Blautia	186801|Clostridia	T	Belongs to the low molecular weight phosphotyrosine protein phosphatase family	yfkJ	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	LMWPc
NFNHFNFO_02236	33035.JPJF01000016_gene4026	1.33e-138	394.0	COG2755@1|root,COG2755@2|Bacteria,1VB88@1239|Firmicutes,24NGQ@186801|Clostridia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NFNHFNFO_02237	33035.JPJF01000016_gene4025	1.54e-145	411.0	COG0664@1|root,COG0664@2|Bacteria,1VBQR@1239|Firmicutes,25CK1@186801|Clostridia,3Y2EU@572511|Blautia	186801|Clostridia	T	helix_turn_helix, cAMP Regulatory protein	-	-	-	ko:K01420	-	-	-	-	ko00000,ko03000	-	-	-	HTH_Crp_2,cNMP_binding
NFNHFNFO_02238	33035.JPJF01000016_gene4024	2.05e-62	191.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia,3Y0FX@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NFNHFNFO_02239	33035.JPJF01000016_gene4023	5.44e-198	550.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3XYM8@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_3
NFNHFNFO_02240	33035.JPJF01000016_gene4022	5.22e-173	483.0	COG0846@1|root,COG0846@2|Bacteria,1V0UI@1239|Firmicutes,24CGT@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	SIR2
NFNHFNFO_02241	33035.JPJF01000016_gene4021	3.17e-130	370.0	COG0356@1|root,COG0356@2|Bacteria,1TQIT@1239|Firmicutes,24A6Q@186801|Clostridia,3XZ99@572511|Blautia	186801|Clostridia	C	it plays a direct role in the translocation of protons across the membrane	atpB	-	-	ko:K02108	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko03110	3.A.2.1	-	-	ATP-synt_A
NFNHFNFO_02242	33035.JPJF01000016_gene4020	1.32e-35	121.0	COG0636@1|root,COG0636@2|Bacteria,1V8SD@1239|Firmicutes,24QMQ@186801|Clostridia,3Y0KZ@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpE	-	-	ko:K02110	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	iHN637.CLJU_RS01165	ATP-synt_C
NFNHFNFO_02243	33035.JPJF01000016_gene4019	1.16e-61	194.0	COG0711@1|root,COG0711@2|Bacteria,1VB85@1239|Firmicutes,24RWR@186801|Clostridia,3Y0CM@572511|Blautia	186801|Clostridia	C	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)	atpF	-	-	ko:K02109	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_B
NFNHFNFO_02244	33035.JPJF01000016_gene4018	1.03e-112	324.0	COG0712@1|root,COG0712@2|Bacteria,1UI0C@1239|Firmicutes,24G5C@186801|Clostridia,3Y09Z@572511|Blautia	186801|Clostridia	C	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation	atpH	-	-	ko:K02113	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	OSCP
NFNHFNFO_02245	33035.JPJF01000016_gene4017	0.0	944.0	COG0056@1|root,COG0056@2|Bacteria,1TNZ8@1239|Firmicutes,248IY@186801|Clostridia,3XZ7P@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit	atpA	-	3.6.3.14	ko:K02111	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_C,ATP-synt_ab_N,OSCP
NFNHFNFO_02246	33035.JPJF01000016_gene4016	1.98e-204	566.0	COG0224@1|root,COG0224@2|Bacteria,1TPBX@1239|Firmicutes,2486Q@186801|Clostridia,3XZ0D@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex	atpG	GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944	-	ko:K02115	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt
NFNHFNFO_02247	33035.JPJF01000016_gene4015	0.0	894.0	COG0055@1|root,COG0055@2|Bacteria,1TPGF@1239|Firmicutes,2489W@186801|Clostridia,3XYVU@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits	atpD	-	3.6.3.14	ko:K02112	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194,ko01000	3.A.2.1	-	-	ATP-synt_ab,ATP-synt_ab_N
NFNHFNFO_02248	33035.JPJF01000016_gene4014	4.14e-88	259.0	COG0355@1|root,COG0355@2|Bacteria,1VA89@1239|Firmicutes,24ND7@186801|Clostridia,3Y0C9@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpC	-	-	ko:K02114	ko00190,ko00195,ko01100,map00190,map00195,map01100	M00157	-	-	ko00000,ko00001,ko00002,ko00194	3.A.2.1	-	-	ATP-synt_DE,ATP-synt_DE_N
NFNHFNFO_02249	469596.HMPREF9488_00516	5.74e-226	627.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,3VSST@526524|Erysipelotrichia	526524|Erysipelotrichia	L	DNA binding domain of tn916 integrase	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_5,Phage_integrase
NFNHFNFO_02250	1121085.AUCI01000001_gene3716	6.58e-81	249.0	COG0684@1|root,COG0684@2|Bacteria,1UZ9U@1239|Firmicutes,4IP4T@91061|Bacilli,1ZPDM@1386|Bacillus	91061|Bacilli	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
NFNHFNFO_02252	1195236.CTER_1677	1.13e-226	648.0	COG2730@1|root,COG2730@2|Bacteria	2|Bacteria	G	polysaccharide catabolic process	-	-	-	-	-	-	-	-	-	-	-	-	BACON,CW_binding_1,Cellulase,DUF4038,DUF5060
NFNHFNFO_02253	553973.CLOHYLEM_05928	1.65e-184	519.0	COG2376@1|root,COG2376@2|Bacteria,1TP92@1239|Firmicutes,2488D@186801|Clostridia,21YFJ@1506553|Lachnoclostridium	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.121	ko:K05878	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak1
NFNHFNFO_02254	553973.CLOHYLEM_05803	3.46e-81	248.0	COG1461@1|root,COG1461@2|Bacteria,1V4FH@1239|Firmicutes,24FUX@186801|Clostridia	186801|Clostridia	S	Dihydroxyacetone kinase, L subunit	-	-	2.7.1.121	ko:K05879	ko00561,ko01100,map00561,map01100	-	R01012	RC00015,RC00017	ko00000,ko00001,ko01000	-	-	-	Dak2
NFNHFNFO_02255	553973.CLOHYLEM_05761	4.21e-69	212.0	COG0698@1|root,COG0698@2|Bacteria,1V2VV@1239|Firmicutes,24GCM@186801|Clostridia,222T7@1506553|Lachnoclostridium	186801|Clostridia	G	Sugar-phosphate isomerase, RpiB LacA LacB family	-	-	-	-	-	-	-	-	-	-	-	-	LacAB_rpiB
NFNHFNFO_02256	1408324.JNJK01000002_gene3407	2.58e-145	421.0	28IPH@1|root,2Z8PG@2|Bacteria,1TREB@1239|Firmicutes,248QM@186801|Clostridia,27KR2@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02257	1226325.HMPREF1548_01647	7.59e-198	554.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,25B0S@186801|Clostridia,36IPH@31979|Clostridiaceae	186801|Clostridia	C	Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate	tdh	-	1.1.1.103	ko:K00060	ko00260,map00260	-	R01465	RC00525	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_02258	1226325.HMPREF1548_01646	0.0	1667.0	COG0674@1|root,COG1013@1|root,COG1014@1|root,COG0674@2|Bacteria,COG1013@2|Bacteria,COG1014@2|Bacteria,1TQJ2@1239|Firmicutes,248FW@186801|Clostridia,36EA6@31979|Clostridiaceae	186801|Clostridia	C	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin	nifJ	-	1.2.7.1	ko:K03737	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00173,M00307	R01196,R10866	RC00004,RC02742	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	EKR,Fer4_16,Fer4_7,PFOR_II,POR,POR_N,TPP_enzyme_C
NFNHFNFO_02260	1226325.HMPREF1548_01644	7.62e-205	575.0	COG2721@1|root,COG2721@2|Bacteria,1TPTX@1239|Firmicutes,24AEC@186801|Clostridia,36G4P@31979|Clostridiaceae	186801|Clostridia	G	D-galactarate dehydratase altronate hydrolase	-	-	4.2.1.7	ko:K16850	ko00040,ko01100,map00040,map01100	M00631	R01540	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	GD_AH_C
NFNHFNFO_02261	1226325.HMPREF1548_01643	1.4e-293	808.0	COG2368@1|root,COG2368@2|Bacteria,1TQ70@1239|Firmicutes,248RP@186801|Clostridia,36DTV@31979|Clostridiaceae	186801|Clostridia	Q	4-hydroxyphenylacetate 3-hydroxylase C terminal	abfD	-	1.14.14.9,4.2.1.120,5.3.3.3	ko:K00483,ko:K14534	ko00350,ko00650,ko00720,ko01100,ko01120,ko01200,ko01220,map00350,map00650,map00720,map01100,map01120,map01200,map01220	M00374,M00375	R02698,R03031,R03299,R10782	RC00046,RC01857,RC03277	ko00000,ko00001,ko00002,ko01000	-	-	-	HpaB,HpaB_N
NFNHFNFO_02262	658086.HMPREF0994_05391	1.22e-222	620.0	COG0183@1|root,COG0183@2|Bacteria,1TP07@1239|Firmicutes,2482I@186801|Clostridia,27J2B@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Thiolase, C-terminal domain	thlA	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
NFNHFNFO_02263	1226325.HMPREF1548_06828	2.22e-118	346.0	COG1024@1|root,COG1024@2|Bacteria,1TQ89@1239|Firmicutes,247RK@186801|Clostridia,36EDS@31979|Clostridiaceae	186801|Clostridia	I	Belongs to the enoyl-CoA hydratase isomerase family	crt	-	4.2.1.17	ko:K01715	ko00650,ko01200,map00650,map01200	-	R03026	RC00831	ko00000,ko00001,ko01000	-	-	-	ECH_1
NFNHFNFO_02264	1163671.JAGI01000002_gene2320	4.15e-136	392.0	COG1250@1|root,COG1250@2|Bacteria,1TPJS@1239|Firmicutes,248AE@186801|Clostridia,36DG5@31979|Clostridiaceae	186801|Clostridia	I	Dehydrogenase	hbd	-	1.1.1.157	ko:K00074	ko00360,ko00362,ko00650,ko01100,ko01120,map00360,map00362,map00650,map01100,map01120	-	R01976,R05576,R06941	RC00029,RC00117	ko00000,ko00001,ko01000	-	-	-	3HCDH,3HCDH_N
NFNHFNFO_02265	1235800.C819_01175	1.16e-155	450.0	COG1960@1|root,COG1960@2|Bacteria,1TP57@1239|Firmicutes,247UB@186801|Clostridia,27K1G@186928|unclassified Lachnospiraceae	186801|Clostridia	I	Acyl-CoA dehydrogenase, C-terminal domain	bcd	-	1.3.8.1	ko:K00248	ko00071,ko00280,ko00650,ko01100,ko01110,ko01120,ko01200,ko01212,map00071,map00280,map00650,map01100,map01110,map01120,map01200,map01212	-	R01175,R01178,R02661,R03172,R04751	RC00052,RC00068,RC00076,RC00120,RC00148	ko00000,ko00001,ko01000	-	-	-	Acyl-CoA_dh_1,Acyl-CoA_dh_M,Acyl-CoA_dh_N
NFNHFNFO_02266	411459.RUMOBE_02489	0.0	1511.0	COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,24AX1@186801|Clostridia,3Y1AM@572511|Blautia	186801|Clostridia	M	LPXTG-motif cell wall anchor domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02267	411459.RUMOBE_02489	1.93e-66	224.0	COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,24AX1@186801|Clostridia,3Y1AM@572511|Blautia	186801|Clostridia	M	LPXTG-motif cell wall anchor domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02268	411470.RUMGNA_03247	5.94e-71	213.0	2BXTH@1|root,2ZZ52@2|Bacteria,1V3TU@1239|Firmicutes,24I3V@186801|Clostridia,3Y1M3@572511|Blautia	186801|Clostridia	S	COG NOG10998 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
NFNHFNFO_02269	411459.RUMOBE_02491	3.42e-84	248.0	28NIV@1|root,2ZBK5@2|Bacteria,1V1U5@1239|Firmicutes,24IAF@186801|Clostridia,3Y1IN@572511|Blautia	186801|Clostridia	S	COG NOG13239 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF961
NFNHFNFO_02270	1196324.A374_16213	8.53e-10	60.5	COG1408@1|root,COG1408@2|Bacteria	2|Bacteria	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	HC2,Metallophos
NFNHFNFO_02271	457412.RSAG_00820	9.48e-51	163.0	COG4734@1|root,COG4734@2|Bacteria,1UZZ6@1239|Firmicutes,24DE1@186801|Clostridia	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NFNHFNFO_02272	457412.RSAG_00819	1.13e-93	273.0	COG4734@1|root,COG4734@2|Bacteria,1V1UX@1239|Firmicutes,24GIR@186801|Clostridia,3WNUH@541000|Ruminococcaceae	186801|Clostridia	S	COG NOG09588 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02273	411461.DORFOR_02738	2.03e-115	331.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249HA@186801|Clostridia,27WSH@189330|Dorea	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NFNHFNFO_02274	457412.RSAG_00816	3.13e-56	176.0	28I70@1|root,2Z89W@2|Bacteria,1V1TC@1239|Firmicutes,24FQV@186801|Clostridia,3WIZ3@541000|Ruminococcaceae	186801|Clostridia	S	TcpE family	-	-	-	-	-	-	-	-	-	-	-	-	TcpE
NFNHFNFO_02275	411461.DORFOR_02747	1.13e-44	144.0	COG0582@1|root,COG0582@2|Bacteria,1VBGF@1239|Firmicutes,24NRM@186801|Clostridia,27X71@189330|Dorea	186801|Clostridia	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	Spo0A_C
NFNHFNFO_02276	411461.DORFOR_02752	1.57e-97	283.0	COG1595@1|root,COG1595@2|Bacteria,1V1UU@1239|Firmicutes,24G23@186801|Clostridia,27WUK@189330|Dorea	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
NFNHFNFO_02277	742765.HMPREF9457_03269	4.74e-51	161.0	2AWCN@1|root,31N8H@2|Bacteria,1V7KM@1239|Firmicutes,25E1E@186801|Clostridia,27VXC@189330|Dorea	186801|Clostridia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NFNHFNFO_02278	411461.DORFOR_02756	0.0	947.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,27VSS@189330|Dorea	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_int_SAM_5,Phage_integrase
NFNHFNFO_02280	33035.JPJF01000104_gene2580	0.0	1039.0	COG4447@1|root,COG4733@1|root,COG4447@2|Bacteria,COG4733@2|Bacteria	2|Bacteria	S	cellulase activity	-	GO:0003674,GO:0005488,GO:0005515,GO:0042802	2.7.11.1,3.2.1.4,3.2.1.78	ko:K01179,ko:K01218,ko:K12132	ko00051,ko00500,ko01100,ko02024,map00051,map00500,map01100,map02024	-	R01332,R06200,R11307,R11308	RC00467	ko00000,ko00001,ko01000,ko01001	-	GH26,GH5,GH9	-	CBM_2,CBM_3,Dockerin_1,Glyco_hydro_9,fn3
NFNHFNFO_02281	33035.JPJF01000104_gene2579	0.0	1068.0	COG0004@1|root,COG0004@2|Bacteria,1TQYG@1239|Firmicutes,247W1@186801|Clostridia,3XYYP@572511|Blautia	186801|Clostridia	P	COG COG0004 Ammonia permease	-	-	-	ko:K03320	-	-	-	-	ko00000,ko02000	1.A.11	-	-	Ammonium_transp,P-II
NFNHFNFO_02282	33035.JPJF01000104_gene2578	0.0	899.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3XYNJ@572511|Blautia	186801|Clostridia	F	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine	purF	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_6,GATase_7,Pribosyltran
NFNHFNFO_02283	33035.JPJF01000104_gene2577	0.0	1301.0	COG3968@1|root,COG3968@2|Bacteria,1UHUF@1239|Firmicutes,2481B@186801|Clostridia,3XZ1H@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	glnA1	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	GSIII_N,Gln-synt_C
NFNHFNFO_02284	877414.ATWA01000041_gene1535	1.22e-211	590.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,26A52@186813|unclassified Clostridiales	186801|Clostridia	C	Acetokinase family	buk	-	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
NFNHFNFO_02285	877414.ATWA01000013_gene2354	1.28e-190	535.0	COG0280@1|root,COG0280@2|Bacteria,1TS7B@1239|Firmicutes,2496E@186801|Clostridia,26CM4@186813|unclassified Clostridiales	186801|Clostridia	C	Phosphate acetyl/butaryl transferase	-	-	2.3.1.8	ko:K00625	ko00430,ko00620,ko00640,ko00680,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00680,map00720,map01100,map01120,map01200	M00357,M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTA_PTB
NFNHFNFO_02286	97139.C824_03840	2.77e-49	159.0	COG4922@1|root,COG4922@2|Bacteria,1VEC0@1239|Firmicutes,24JEI@186801|Clostridia,36PYK@31979|Clostridiaceae	186801|Clostridia	S	SnoaL-like polyketide cyclase	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL
NFNHFNFO_02287	658655.HMPREF0988_01431	5.05e-188	545.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,27UFA@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
NFNHFNFO_02288	658655.HMPREF0988_01430	5.05e-159	453.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,27N0H@186928|unclassified Lachnospiraceae	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_02289	556261.HMPREF0240_00603	3.62e-181	508.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,36E1E@31979|Clostridiaceae	186801|Clostridia	EP	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
NFNHFNFO_02290	658655.HMPREF0988_01428	1.64e-180	508.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,27JHK@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
NFNHFNFO_02291	658655.HMPREF0988_01427	8.38e-196	546.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,27JBD@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
NFNHFNFO_02292	588581.Cpap_2813	6.06e-280	773.0	COG1053@1|root,COG1053@2|Bacteria,1TT1Q@1239|Firmicutes,249N4@186801|Clostridia,3WHHS@541000|Ruminococcaceae	186801|Clostridia	C	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	FAD_binding_2,FMN_bind
NFNHFNFO_02293	97139.C824_03811	4.02e-242	702.0	COG3664@1|root,COG4977@1|root,COG3664@2|Bacteria,COG4977@2|Bacteria,1TQGI@1239|Firmicutes,2490Q@186801|Clostridia,36GCA@31979|Clostridiaceae	186801|Clostridia	K	family 39	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,Glyco_hydro_39,HTH_18
NFNHFNFO_02294	97139.C824_03941	3.55e-167	474.0	COG0655@1|root,COG0655@2|Bacteria,1UYDQ@1239|Firmicutes,24BAR@186801|Clostridia,36H9Z@31979|Clostridiaceae	186801|Clostridia	S	NADPH-dependent FMN reductase	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NFNHFNFO_02295	227377.CBU_0221	2.02e-13	74.3	COG2091@1|root,COG2091@2|Bacteria,1MZHC@1224|Proteobacteria,1SCGA@1236|Gammaproteobacteria,1JDBR@118969|Legionellales	118969|Legionellales	H	4'-phosphopantetheinyl transferase superfamily	-	-	-	ko:K06133	ko00770,map00770	-	R01625	RC00002	ko00000,ko00001,ko01000	-	-	-	ACPS
NFNHFNFO_02296	931276.Cspa_c47630	1.15e-172	514.0	COG3711@1|root,COG3711@2|Bacteria,1TQT1@1239|Firmicutes,249R8@186801|Clostridia	186801|Clostridia	GKT	Psort location Cytoplasmic, score	-	-	-	ko:K03491	-	-	-	-	ko00000,ko03000	-	-	-	HTH_11,Mga,PRD,PTS_EIIA_2
NFNHFNFO_02297	588581.Cpap_2791	9.91e-193	544.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,249X1@186801|Clostridia,3WJCU@541000|Ruminococcaceae	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NFNHFNFO_02298	97139.C824_03947	2.17e-141	414.0	COG0477@1|root,COG2814@2|Bacteria,1UZXR@1239|Firmicutes,25CFX@186801|Clostridia,36WVE@31979|Clostridiaceae	186801|Clostridia	EGP	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NFNHFNFO_02299	588581.Cpap_2788	5.51e-212	590.0	COG0111@1|root,COG0111@2|Bacteria,1V410@1239|Firmicutes,24EUD@186801|Clostridia,3WIUB@541000|Ruminococcaceae	186801|Clostridia	C	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.310	ko:K16843	ko00270,map00270	-	R05693	RC00031	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NFNHFNFO_02300	411490.ANACAC_03806	6.2e-98	290.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia	186801|Clostridia	G	L-ribulose-5-phosphate 4-epimerase	-	-	4.1.2.17	ko:K01628	ko00051,ko01120,map00051,map01120	-	R02262	RC00603,RC00604	ko00000,ko00001,ko01000	-	-	-	Aldolase_II
NFNHFNFO_02301	1280698.AUJS01000039_gene2452	2.42e-261	729.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,27WE7@189330|Dorea	186801|Clostridia	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_02303	1042156.CXIVA_15980	4.27e-123	362.0	COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,24AF7@186801|Clostridia,36GBX@31979|Clostridiaceae	186801|Clostridia	G	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)	iolE	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
NFNHFNFO_02304	1123304.AQYA01000023_gene1494	1.78e-39	138.0	COG0346@1|root,COG0346@2|Bacteria,1VK1Y@1239|Firmicutes	1239|Firmicutes	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_4
NFNHFNFO_02305	588581.Cpap_2805	1.22e-116	346.0	COG0667@1|root,COG0667@2|Bacteria,1TQYY@1239|Firmicutes,24JUU@186801|Clostridia,3WGRS@541000|Ruminococcaceae	186801|Clostridia	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NFNHFNFO_02306	1232436.CAPF01000040_gene408	1.49e-236	659.0	COG0183@1|root,COG0183@2|Bacteria,2HQJS@201174|Actinobacteria,4CUEK@84998|Coriobacteriia	84998|Coriobacteriia	I	Belongs to the thiolase family	-	-	2.3.1.9	ko:K00626	ko00071,ko00072,ko00280,ko00310,ko00362,ko00380,ko00620,ko00630,ko00640,ko00650,ko00720,ko00900,ko01100,ko01110,ko01120,ko01130,ko01200,ko01212,ko02020,map00071,map00072,map00280,map00310,map00362,map00380,map00620,map00630,map00640,map00650,map00720,map00900,map01100,map01110,map01120,map01130,map01200,map01212,map02020	M00088,M00095,M00373,M00374,M00375	R00238,R01177	RC00004,RC00326	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Thiolase_C,Thiolase_N
NFNHFNFO_02307	1232436.CAPF01000040_gene407	5.11e-57	181.0	COG1545@1|root,COG1545@2|Bacteria,2HVHS@201174|Actinobacteria,4CWVA@84998|Coriobacteriia	84998|Coriobacteriia	S	DUF35 OB-fold domain, acyl-CoA-associated	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02309	1256908.HMPREF0373_02736	0.0	1080.0	COG0493@1|root,COG3383@1|root,COG0493@2|Bacteria,COG3383@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,25UR0@186806|Eubacteriaceae	186801|Clostridia	C	NADPH-dependent glutamate synthase beta chain and related oxidoreductases	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4,Fer4_20,Fer4_7,NADH-G_4Fe-4S_3,Pyr_redox_2
NFNHFNFO_02310	588581.Cpap_2811	8.84e-125	374.0	COG1145@1|root,COG1894@1|root,COG1145@2|Bacteria,COG1894@2|Bacteria,1TQB0@1239|Firmicutes,2483E@186801|Clostridia,3WGG2@541000|Ruminococcaceae	186801|Clostridia	C	NADH ubiquinone oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NADH_4Fe-4S
NFNHFNFO_02311	588581.Cpap_2799	7.48e-215	595.0	COG1082@1|root,COG1082@2|Bacteria,1TPJT@1239|Firmicutes,24DB5@186801|Clostridia	186801|Clostridia	G	AP endonuclease family 2 C terminus	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2,AP_endonuc_2_N
NFNHFNFO_02312	588581.Cpap_2798	1.52e-223	622.0	COG0673@1|root,COG0673@2|Bacteria,1TSWE@1239|Firmicutes,24CB6@186801|Clostridia,3WRKP@541000|Ruminococcaceae	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_02313	1235798.C817_03144	0.0	980.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,27W9G@189330|Dorea	186801|Clostridia	C	NADH:flavin oxidoreductase / NADH oxidase family	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NFNHFNFO_02314	33035.JPJF01000017_gene3824	0.0	1026.0	COG0504@1|root,COG0504@2|Bacteria,1TP34@1239|Firmicutes,2482E@186801|Clostridia,3XZPG@572511|Blautia	186801|Clostridia	F	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates	pyrG	-	6.3.4.2	ko:K01937	ko00240,ko01100,map00240,map01100	M00052	R00571,R00573	RC00010,RC00074	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS01075	CTP_synth_N,GATase
NFNHFNFO_02315	33035.JPJF01000017_gene3823	0.0	2851.0	COG0067@1|root,COG0069@1|root,COG0070@1|root,COG0067@2|Bacteria,COG0069@2|Bacteria,COG0070@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,3XZ2S@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	gltB	-	1.4.1.13,1.4.1.14,1.4.7.1	ko:K00265,ko:K00284	ko00250,ko00630,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00630,map00910,map01100,map01110,map01120,map01130,map01230	-	R00021,R00093,R00114,R00248,R10086	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	GATase_2,GXGXG,Glu_syn_central,Glu_synthase
NFNHFNFO_02316	33035.JPJF01000017_gene3822	0.0	947.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,2490X@186801|Clostridia,3XZHX@572511|Blautia	186801|Clostridia	C	NADH-dependent glutamate synthase small subunit	gltD	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2
NFNHFNFO_02317	33035.JPJF01000017_gene3821	3.4e-286	783.0	COG0407@1|root,COG0407@2|Bacteria,1TRJG@1239|Firmicutes,24B34@186801|Clostridia	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_02318	33035.JPJF01000017_gene3820	0.0	1109.0	COG0514@1|root,COG0514@2|Bacteria,1TPN5@1239|Firmicutes,247ZA@186801|Clostridia,3XYQ1@572511|Blautia	186801|Clostridia	L	RQC	recQ	-	3.6.4.12	ko:K03654	ko03018,map03018	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DEAD,HRDC,HTH_40,Helicase_C,RQC,RecQ_Zn_bind
NFNHFNFO_02321	33035.JPJF01000018_gene4320	9.39e-144	407.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,3XZ8R@572511|Blautia	186801|Clostridia	I	Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP)	ispD	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS20335	IspD
NFNHFNFO_02322	33035.JPJF01000018_gene4321	3.56e-236	650.0	COG0533@1|root,COG0533@2|Bacteria,1TQDR@1239|Firmicutes,247MG@186801|Clostridia,3XYPY@572511|Blautia	186801|Clostridia	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction	tsaD	-	2.3.1.234	ko:K01409	-	-	R10648	RC00070,RC00416	ko00000,ko01000,ko03016	-	-	-	Peptidase_M22
NFNHFNFO_02323	33035.JPJF01000018_gene4322	2.01e-213	590.0	COG1234@1|root,COG1234@2|Bacteria,1TRGP@1239|Firmicutes,248EQ@186801|Clostridia,3XZ6W@572511|Blautia	186801|Clostridia	S	Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA	rnz	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
NFNHFNFO_02324	33035.JPJF01000018_gene4323	4.14e-55	171.0	2EJD6@1|root,33D47@2|Bacteria,1VKED@1239|Firmicutes,24T7S@186801|Clostridia,3Y0IQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02325	33035.JPJF01000018_gene4324	2.36e-84	250.0	COG0454@1|root,COG0456@2|Bacteria,1V6KU@1239|Firmicutes,24J9Z@186801|Clostridia,3Y0DF@572511|Blautia	186801|Clostridia	K	This enzyme acetylates the N-terminal alanine of ribosomal protein S18	rimI	-	2.3.1.128	ko:K03789	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_1,Acetyltransf_10
NFNHFNFO_02326	33035.JPJF01000018_gene4325	1.91e-153	433.0	COG1214@1|root,COG1214@2|Bacteria,1V4YX@1239|Firmicutes,24A0P@186801|Clostridia,3XYQX@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	yeaZ	-	-	ko:K14742	-	-	-	-	ko00000,ko03016	-	-	-	Acetyltransf_1,Peptidase_M22
NFNHFNFO_02327	33035.JPJF01000018_gene4326	2.78e-98	285.0	COG0802@1|root,COG0802@2|Bacteria,1V6CV@1239|Firmicutes,24MSS@186801|Clostridia,3Y003@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ydiB	-	-	ko:K06925	-	-	-	-	ko00000,ko03016	-	-	-	TsaE
NFNHFNFO_02328	33035.JPJF01000018_gene4328	2.39e-106	308.0	COG0652@1|root,COG0652@2|Bacteria,1TRHW@1239|Firmicutes,247XN@186801|Clostridia,3XZDN@572511|Blautia	186801|Clostridia	O	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides	ppiB	-	5.2.1.8	ko:K03768	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Pro_isomerase
NFNHFNFO_02329	33035.JPJF01000018_gene4329	1.72e-135	385.0	COG1739@1|root,COG1739@2|Bacteria,1V6MQ@1239|Firmicutes,248W7@186801|Clostridia,3XYJT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yvyE	-	-	-	-	-	-	-	-	-	-	-	DUF1949,UPF0029
NFNHFNFO_02330	33035.JPJF01000018_gene4330	0.0	1552.0	COG5009@1|root,COG5009@2|Bacteria,1UI0H@1239|Firmicutes,25E95@186801|Clostridia,3XZCE@572511|Blautia	186801|Clostridia	M	Psort location Extracellular, score 9.55	-	-	2.4.1.129,3.4.16.4	ko:K05366	ko00550,ko01100,ko01501,map00550,map01100,map01501	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01011	-	GT51	-	Transgly,Transpeptidase
NFNHFNFO_02331	33035.JPJF01000018_gene4331	1.57e-208	578.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3XYHF@572511|Blautia	186801|Clostridia	GK	Psort location Cytoplasmic, score	glcK	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
NFNHFNFO_02332	33035.JPJF01000018_gene4332	4.23e-218	602.0	COG1493@1|root,COG1493@2|Bacteria,1TP5Z@1239|Firmicutes,24999@186801|Clostridia,3XZ5K@572511|Blautia	186801|Clostridia	H	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion	hprK	-	-	ko:K06023	-	-	-	-	ko00000,ko01000	-	-	-	Hpr_kinase_C,Hpr_kinase_N
NFNHFNFO_02333	33035.JPJF01000018_gene4333	0.0	1179.0	COG0322@1|root,COG0322@2|Bacteria,1TP4B@1239|Firmicutes,247TQ@186801|Clostridia,3XZ8C@572511|Blautia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision	uvrC	-	-	ko:K03703	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	GIY-YIG,HHH_2,HHH_5,UVR,UvrC_HhH_N
NFNHFNFO_02334	33035.JPJF01000018_gene4334	0.0	1130.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XYZH@572511|Blautia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NFNHFNFO_02335	33035.JPJF01000018_gene4335	0.0	954.0	COG4868@1|root,COG4868@2|Bacteria,1TQYE@1239|Firmicutes,247YI@186801|Clostridia,3XYIV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1846
NFNHFNFO_02336	33035.JPJF01000018_gene4336	3.24e-250	686.0	COG1087@1|root,COG1087@2|Bacteria,1TQ7N@1239|Firmicutes,247M9@186801|Clostridia,3XYYJ@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	galE	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase,GDP_Man_Dehyd
NFNHFNFO_02337	33035.JPJF01000018_gene4337	3.14e-254	698.0	COG2334@1|root,COG2334@2|Bacteria,1UXS1@1239|Firmicutes,25MC4@186801|Clostridia,3XZ7J@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	APH
NFNHFNFO_02338	33035.JPJF01000018_gene4338	5.12e-216	597.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3XYY9@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
NFNHFNFO_02339	33035.JPJF01000018_gene4339	7.47e-204	565.0	COG2207@1|root,COG2207@2|Bacteria,1UYFM@1239|Firmicutes,247WN@186801|Clostridia,3XZJ7@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_02340	33035.JPJF01000018_gene4340	1.57e-168	471.0	COG0363@1|root,COG0363@2|Bacteria,1TP10@1239|Firmicutes,248HK@186801|Clostridia,3XYUH@572511|Blautia	186801|Clostridia	G	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion	nagB	-	3.5.99.6	ko:K02564	ko00520,ko01100,map00520,map01100	-	R00765	RC00163	ko00000,ko00001,ko01000	-	-	-	Glucosamine_iso
NFNHFNFO_02341	33035.JPJF01000018_gene4341	1.5e-244	679.0	COG1668@1|root,COG1668@2|Bacteria,1TXRK@1239|Firmicutes,248YS@186801|Clostridia,3Y1AQ@572511|Blautia	186801|Clostridia	CP	ABC-2 family transporter protein	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
NFNHFNFO_02342	33035.JPJF01000018_gene4342	8e-199	552.0	COG4152@1|root,COG4152@2|Bacteria,1TR06@1239|Firmicutes,249YC@186801|Clostridia,3Y10M@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4162)	natA	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
NFNHFNFO_02343	33035.JPJF01000018_gene4343	8.43e-124	358.0	2C5AG@1|root,32T9Z@2|Bacteria,1VDDZ@1239|Firmicutes,24S1R@186801|Clostridia,3Y1SX@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3169)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3169
NFNHFNFO_02344	33035.JPJF01000018_gene4344	8.97e-38	127.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QPB@186801|Clostridia,3Y0JP@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NFNHFNFO_02345	33035.JPJF01000018_gene4345	3.13e-158	448.0	COG1266@1|root,COG1266@2|Bacteria,1W749@1239|Firmicutes,25MB2@186801|Clostridia,3Y0CJ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Abi
NFNHFNFO_02346	33035.JPJF01000018_gene4346	1.01e-283	778.0	COG0014@1|root,COG0014@2|Bacteria,1TQ9V@1239|Firmicutes,248NX@186801|Clostridia,3XZ50@572511|Blautia	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate	proA	-	1.2.1.41	ko:K00147	ko00330,ko00332,ko01100,ko01110,ko01130,ko01230,map00330,map00332,map01100,map01110,map01130,map01230	M00015	R03313	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
NFNHFNFO_02347	33035.JPJF01000018_gene4347	1.61e-157	442.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,3XZ85@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_02348	33035.JPJF01000019_gene4317	0.0	1414.0	COG2217@1|root,COG2217@2|Bacteria,1TQ07@1239|Firmicutes,248EH@186801|Clostridia,3XZ79@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	cadA	-	3.6.3.3,3.6.3.5	ko:K01534	-	-	-	-	ko00000,ko01000	3.A.3.6	-	-	E1-E2_ATPase,HMA,Hydrolase
NFNHFNFO_02349	33035.JPJF01000019_gene4316	1.74e-37	125.0	2EGE3@1|root,33A60@2|Bacteria,1VMF7@1239|Firmicutes,24UMV@186801|Clostridia,3Y0J2@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02350	33035.JPJF01000019_gene4315	1.18e-308	843.0	COG0569@1|root,COG0569@2|Bacteria,1TPNS@1239|Firmicutes,24830@186801|Clostridia,3XZ02@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	trkA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NFNHFNFO_02351	33035.JPJF01000019_gene4314	0.0	896.0	COG0168@1|root,COG0168@2|Bacteria,1TPAF@1239|Firmicutes,248K4@186801|Clostridia,3XYTG@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	trkH	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NFNHFNFO_02352	33035.JPJF01000019_gene4313	1.96e-142	402.0	COG3546@1|root,COG3546@2|Bacteria,1TQVQ@1239|Firmicutes,247YJ@186801|Clostridia,3XYJ2@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	cotJC	-	-	ko:K06334	-	-	-	-	ko00000	-	-	-	Mn_catalase
NFNHFNFO_02353	33035.JPJF01000019_gene4312	5.1e-93	272.0	2ERDA@1|root,33IYY@2|Bacteria,1VQDH@1239|Firmicutes,24MN4@186801|Clostridia,3Y1ZV@572511|Blautia	186801|Clostridia	S	Spore coat associated protein JA (CotJA)	-	-	-	-	-	-	-	-	-	-	-	-	CotJA,CotJB
NFNHFNFO_02354	33035.JPJF01000019_gene4311	4.5e-73	219.0	COG1695@1|root,COG1695@2|Bacteria,1VA94@1239|Firmicutes,24N33@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
NFNHFNFO_02355	33035.JPJF01000019_gene4310	5e-132	377.0	2AKUT@1|root,31BMY@2|Bacteria,1V967@1239|Firmicutes,24DHX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02356	33035.JPJF01000019_gene4309	2.16e-123	363.0	COG3595@1|root,COG3595@2|Bacteria,1VGMF@1239|Firmicutes,24ICY@186801|Clostridia	186801|Clostridia	S	Putative adhesin	-	-	-	-	-	-	-	-	-	-	-	-	DUF4097
NFNHFNFO_02357	33035.JPJF01000019_gene4308	5.23e-295	808.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XZJP@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
NFNHFNFO_02358	33035.JPJF01000019_gene4307	1.41e-155	437.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24D6A@186801|Clostridia,3XYH5@572511|Blautia	186801|Clostridia	T	positive response regulator for pho regulon	phoB	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_02359	33035.JPJF01000019_gene4306	0.0	972.0	COG1283@1|root,COG1283@2|Bacteria,1TP4K@1239|Firmicutes,247KT@186801|Clostridia,3XYUW@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K03324	-	-	-	-	ko00000,ko02000	2.A.58.2	-	-	Na_Pi_cotrans,PhoU
NFNHFNFO_02360	33035.JPJF01000019_gene4305	3.22e-155	439.0	COG1246@1|root,COG1246@2|Bacteria,1TRN6@1239|Firmicutes,2484V@186801|Clostridia	186801|Clostridia	E	YoaP-like	yoaP	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,YoaP
NFNHFNFO_02361	33035.JPJF01000019_gene4303	2.2e-272	745.0	COG0673@1|root,COG0673@2|Bacteria,1V0MQ@1239|Firmicutes,24CZ7@186801|Clostridia,3XZSH@572511|Blautia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NFNHFNFO_02362	33035.JPJF01000019_gene4302	0.0	948.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,25B1H@186801|Clostridia	186801|Clostridia	T	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_02363	33035.JPJF01000019_gene4301	9.96e-175	489.0	COG0395@1|root,COG0395@2|Bacteria,1TSJ9@1239|Firmicutes,24ERB@186801|Clostridia	186801|Clostridia	P	abc transporter permease protein	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_02364	33035.JPJF01000019_gene4300	3.26e-197	548.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia	2|Bacteria	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
NFNHFNFO_02365	33035.JPJF01000019_gene4299	1.75e-289	793.0	COG1653@1|root,COG1653@2|Bacteria,1TQJU@1239|Firmicutes,24AHT@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02367	33035.JPJF01000019_gene4298	0.0	919.0	COG2972@1|root,COG2972@2|Bacteria,1TSE1@1239|Firmicutes	2|Bacteria	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NFNHFNFO_02368	33035.JPJF01000019_gene4297	8.33e-188	522.0	COG0005@1|root,COG0005@2|Bacteria,1TQ37@1239|Firmicutes,247KQ@186801|Clostridia,3XZ1R@572511|Blautia	186801|Clostridia	F	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate	-	-	2.4.2.1	ko:K03783	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
NFNHFNFO_02369	33035.JPJF01000019_gene4296	8.41e-102	296.0	COG0782@1|root,COG0782@2|Bacteria,1V1G3@1239|Firmicutes,24FRJ@186801|Clostridia,3XZZN@572511|Blautia	186801|Clostridia	K	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides	greA_2	-	-	ko:K03624	-	-	-	-	ko00000,ko03021	-	-	-	GreA_GreB,GreA_GreB_N
NFNHFNFO_02370	33035.JPJF01000019_gene4295	4.67e-116	333.0	COG1827@1|root,COG1827@2|Bacteria,1V6EY@1239|Firmicutes,24JF2@186801|Clostridia,3Y067@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	niaR	-	-	ko:K07105	-	-	-	-	ko00000	-	-	-	3H,HTH_11
NFNHFNFO_02371	33035.JPJF01000019_gene4294	3.51e-191	532.0	COG0157@1|root,COG0157@2|Bacteria,1TPQC@1239|Firmicutes,248P2@186801|Clostridia,3XZ2V@572511|Blautia	186801|Clostridia	H	Belongs to the NadC ModD family	nadC	-	2.4.2.19	ko:K00767	ko00760,ko01100,map00760,map01100	M00115	R03348	RC02877	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12010	QRPTase_C,QRPTase_N
NFNHFNFO_02372	33035.JPJF01000019_gene4293	3.78e-306	835.0	COG0029@1|root,COG0029@2|Bacteria,1UHSP@1239|Firmicutes,25E6F@186801|Clostridia,3XZEH@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 9.36	nadB	-	1.4.3.16	ko:K00278	ko00250,ko00760,ko01100,map00250,map00760,map01100	M00115	R00357,R00481	RC00006,RC02566	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Succ_DH_flav_C
NFNHFNFO_02373	33035.JPJF01000019_gene4292	9.11e-207	573.0	COG0379@1|root,COG0379@2|Bacteria,1TP6R@1239|Firmicutes,247IJ@186801|Clostridia,3XZNN@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate	nadA	-	2.5.1.72	ko:K03517	ko00760,ko01100,map00760,map01100	M00115	R04292	RC01119	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS12020	NadA
NFNHFNFO_02374	33035.JPJF01000019_gene4291	3.47e-129	367.0	COG1309@1|root,COG1309@2|Bacteria,1V89E@1239|Firmicutes,24JQ7@186801|Clostridia,3Y03H@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NFNHFNFO_02375	33035.JPJF01000019_gene4290	2.78e-228	630.0	COG0451@1|root,COG0451@2|Bacteria,1TRTD@1239|Firmicutes,24AFT@186801|Clostridia	186801|Clostridia	M	NAD dependent epimerase dehydratase family	-	-	1.1.1.219	ko:K00091	-	-	-	-	ko00000,ko01000	-	-	-	3Beta_HSD,Epimerase
NFNHFNFO_02376	33035.JPJF01000019_gene4289	6.91e-280	767.0	COG0150@1|root,COG0150@2|Bacteria,1TP9J@1239|Firmicutes,248BT@186801|Clostridia,3XYWD@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AIRS,AIRS_C,HTH_3
NFNHFNFO_02377	33035.JPJF01000019_gene4288	3.03e-262	724.0	COG0534@1|root,COG0534@2|Bacteria,1TP6V@1239|Firmicutes,248EF@186801|Clostridia,3XZ6H@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_02378	33035.JPJF01000019_gene4287	1.2e-95	284.0	COG0622@1|root,COG0622@2|Bacteria,1V7VB@1239|Firmicutes,24PEZ@186801|Clostridia,3Y0BJ@572511|Blautia	186801|Clostridia	S	Calcineurin-like phosphoesterase superfamily domain	-	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NFNHFNFO_02379	33035.JPJF01000019_gene4286	1.78e-29	107.0	2EIWS@1|root,33CN3@2|Bacteria,1VMC7@1239|Firmicutes,24R1C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02380	33035.JPJF01000019_gene4285	2.03e-155	439.0	COG4200@1|root,COG4200@2|Bacteria,1TRGZ@1239|Firmicutes,2498Y@186801|Clostridia,3Y1ZR@572511|Blautia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K20461	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
NFNHFNFO_02381	33035.JPJF01000019_gene4284	7.98e-145	411.0	COG4200@1|root,COG4200@2|Bacteria,1TP4G@1239|Firmicutes,249XU@186801|Clostridia,3Y26T@572511|Blautia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K20460	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
NFNHFNFO_02382	33035.JPJF01000019_gene4283	7.63e-169	473.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,3Y1EC@572511|Blautia	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K20459	ko02010,map02010	M00254,M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
NFNHFNFO_02383	33035.JPJF01000019_gene4282	1.94e-154	435.0	COG0745@1|root,COG0745@2|Bacteria,1TYPK@1239|Firmicutes,247Y9@186801|Clostridia,3Y11C@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_02384	33035.JPJF01000019_gene4281	1.77e-286	788.0	COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,24AAW@186801|Clostridia,3Y16H@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_02385	33035.JPJF01000019_gene4279	1.5e-137	391.0	COG3619@1|root,COG3619@2|Bacteria,1V1VQ@1239|Firmicutes,24DUE@186801|Clostridia,3Y00W@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1275
NFNHFNFO_02386	33035.JPJF01000019_gene4278	3.15e-160	454.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3XZVT@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_02387	33035.JPJF01000019_gene4277	0.0	1640.0	COG0480@1|root,COG0480@2|Bacteria,1TPQH@1239|Firmicutes,247X4@186801|Clostridia,3XYMW@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	tetP	-	-	-	-	-	-	-	-	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,NYN_YacP
NFNHFNFO_02388	33035.JPJF01000019_gene4276	2.36e-66	204.0	COG0727@1|root,COG0727@2|Bacteria,1V67G@1239|Firmicutes,24I48@186801|Clostridia	186801|Clostridia	S	Putative zinc- or iron-chelating domain	-	-	-	ko:K06940	-	-	-	-	ko00000	-	-	-	CxxCxxCC
NFNHFNFO_02389	33035.JPJF01000019_gene4275	4.46e-145	413.0	COG1396@1|root,COG1396@2|Bacteria,1VF0W@1239|Firmicutes,24R43@186801|Clostridia,3Y0KW@572511|Blautia	186801|Clostridia	K	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_02390	33035.JPJF01000019_gene4272	0.0	1177.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia,3XYS3@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score 7.63	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD,Usp
NFNHFNFO_02391	33035.JPJF01000019_gene4271	2.62e-120	346.0	COG2156@1|root,COG2156@2|Bacteria,1V4GE@1239|Firmicutes,24G0R@186801|Clostridia,3Y03P@572511|Blautia	186801|Clostridia	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex	kdpC	-	3.6.3.12	ko:K01548	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpC
NFNHFNFO_02392	33035.JPJF01000019_gene4270	0.0	1223.0	COG2216@1|root,COG2216@2|Bacteria,1TPV5@1239|Firmicutes,24835@186801|Clostridia,3XYQW@572511|Blautia	186801|Clostridia	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system	kdpB	-	3.6.3.12	ko:K01547	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	E1-E2_ATPase,Hydrolase
NFNHFNFO_02393	33035.JPJF01000019_gene4269	0.0	1053.0	COG2060@1|root,COG2060@2|Bacteria,1TPDF@1239|Firmicutes,24868@186801|Clostridia,3XZKR@572511|Blautia	186801|Clostridia	P	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane	kdpA	-	3.6.3.12	ko:K01546	ko02020,map02020	-	-	-	ko00000,ko00001,ko01000	3.A.3.7	-	-	KdpA
NFNHFNFO_02395	33035.JPJF01000042_gene402	6.77e-74	225.0	2AE00@1|root,313SJ@2|Bacteria,1V6FJ@1239|Firmicutes,24JFA@186801|Clostridia,3Y02Y@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.75	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02396	33035.JPJF01000042_gene403	1.22e-213	598.0	COG0544@1|root,COG0544@2|Bacteria,1V3TE@1239|Firmicutes,24AAA@186801|Clostridia,3Y00S@572511|Blautia	186801|Clostridia	M	COG COG0544 FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor)	tig_1	-	-	ko:K03545	-	-	-	-	ko00000	-	-	-	FKBP_C,Trigger_C
NFNHFNFO_02397	33035.JPJF01000042_gene404	0.0	1244.0	COG0768@1|root,COG0768@2|Bacteria,1TQHY@1239|Firmicutes,248PI@186801|Clostridia,3XZ30@572511|Blautia	186801|Clostridia	M	penicillin-binding protein 2'	pbpC	-	3.4.16.4	ko:K05515,ko:K21467	ko00550,ko01501,map00550,map01501	-	-	-	ko00000,ko00001,ko01000,ko01011	-	-	-	MecA_N,PBP_dimer,Transpeptidase
NFNHFNFO_02398	33035.JPJF01000042_gene405	2.6e-236	656.0	28IBJ@1|root,2Z8XY@2|Bacteria,1UCWW@1239|Firmicutes,24DUG@186801|Clostridia,3XZIT@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02399	33035.JPJF01000042_gene406	1.14e-82	244.0	2E5KN@1|root,330BS@2|Bacteria,1V5P2@1239|Firmicutes,24TCR@186801|Clostridia,3Y0HH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02400	33035.JPJF01000042_gene407	2.1e-271	743.0	COG2263@1|root,COG2263@2|Bacteria,1TQUZ@1239|Firmicutes,248AM@186801|Clostridia,3XZ7H@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_32
NFNHFNFO_02401	33035.JPJF01000042_gene408	0.0	1503.0	28IKE@1|root,2Z8M5@2|Bacteria,1TP2B@1239|Firmicutes,248C2@186801|Clostridia,3XYUK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	GcvP	-	-	-	-	-	-	-	-	-	-	-	Peptidase_C39_2
NFNHFNFO_02402	33035.JPJF01000042_gene409	7.59e-268	733.0	COG2309@1|root,COG2309@2|Bacteria,1TP65@1239|Firmicutes,24AR8@186801|Clostridia,3Y0UP@572511|Blautia	186801|Clostridia	E	Thermophilic metalloprotease (M29)	-	-	-	ko:K19689	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M29
NFNHFNFO_02403	33035.JPJF01000042_gene410	1.44e-153	437.0	COG2333@1|root,COG2333@2|Bacteria,1UUV9@1239|Firmicutes,25KC1@186801|Clostridia,3Y1Z0@572511|Blautia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Lactamase_B
NFNHFNFO_02404	33035.JPJF01000042_gene411	7.51e-58	182.0	2B6X3@1|root,31ZX0@2|Bacteria,1VH5G@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02405	33035.JPJF01000042_gene412	2.39e-38	128.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QPB@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NFNHFNFO_02406	1226325.HMPREF1548_00168	3.59e-266	747.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,36EDH@31979|Clostridiaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NFNHFNFO_02407	1226325.HMPREF1548_00167	1.69e-173	493.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_02408	1226325.HMPREF1548_00165	3.7e-236	659.0	COG1653@1|root,COG1653@2|Bacteria,1UYSZ@1239|Firmicutes,25BW9@186801|Clostridia,36IUA@31979|Clostridiaceae	186801|Clostridia	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1
NFNHFNFO_02409	1226325.HMPREF1548_00164	1.5e-170	481.0	COG1175@1|root,COG1175@2|Bacteria,1TRC0@1239|Firmicutes,25C59@186801|Clostridia,36WPU@31979|Clostridiaceae	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_02410	1226325.HMPREF1548_00163	5.12e-162	458.0	COG0395@1|root,COG0395@2|Bacteria,1TT5G@1239|Firmicutes,249MU@186801|Clostridia,36GNW@31979|Clostridiaceae	186801|Clostridia	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17236	ko02010,map02010	M00602	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.34	-	-	BPD_transp_1
NFNHFNFO_02411	1449050.JNLE01000003_gene3503	6.42e-218	625.0	COG1053@1|root,COG1053@2|Bacteria,1UM4U@1239|Firmicutes,24AI4@186801|Clostridia,36DHI@31979|Clostridiaceae	186801|Clostridia	C	FAD dependent oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	FAD_oxidored
NFNHFNFO_02412	33035.JPJF01000042_gene413	1.11e-101	296.0	COG1595@1|root,COG1595@2|Bacteria,1V6SV@1239|Firmicutes,24HPR@186801|Clostridia,3Y0EF@572511|Blautia	186801|Clostridia	K	COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_ECF,Sigma70_r2,Sigma70_r4,Sigma70_r4_2
NFNHFNFO_02413	33035.JPJF01000042_gene414	0.0	1117.0	COG1948@1|root,COG4880@2|Bacteria,1TQK0@1239|Firmicutes,247VC@186801|Clostridia,3XZHF@572511|Blautia	186801|Clostridia	L	COG COG4880 Secreted protein containing C-terminal beta-propeller domain distantly related to WD-40 repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_propel
NFNHFNFO_02414	33035.JPJF01000042_gene415	0.0	922.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,2484D@186801|Clostridia,3XZAQ@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	asnS	-	6.1.1.22	ko:K01893	ko00970,map00970	M00359,M00360	R03648	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_2,tRNA_anti-codon
NFNHFNFO_02415	33035.JPJF01000042_gene416	7.72e-235	648.0	COG0420@1|root,COG0420@2|Bacteria,1TWMI@1239|Firmicutes,24BN3@186801|Clostridia,3XZ47@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,Metallophos_2
NFNHFNFO_02416	33035.JPJF01000042_gene417	0.0	872.0	COG4717@1|root,COG4717@2|Bacteria,1TQP3@1239|Firmicutes,24E0A@186801|Clostridia,3XZEZ@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AAA_23,AAA_27
NFNHFNFO_02417	658088.HMPREF0987_00828	1.24e-227	635.0	COG1653@1|root,COG1653@2|Bacteria,1TT8P@1239|Firmicutes,25FNF@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02418	658088.HMPREF0987_00827	2.21e-168	475.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,249MK@186801|Clostridia,27K7U@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_02419	478749.BRYFOR_05875	1.23e-156	444.0	COG0395@1|root,COG0395@2|Bacteria,1TR01@1239|Firmicutes,249Z7@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_02420	658088.HMPREF0987_00825	2.83e-263	736.0	2DB9B@1|root,2Z7VY@2|Bacteria,1UHZN@1239|Firmicutes,24AP5@186801|Clostridia,27JVY@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4091)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4091
NFNHFNFO_02421	658088.HMPREF0987_00824	1.3e-133	388.0	COG2207@1|root,COG2207@2|Bacteria,1UYFM@1239|Firmicutes,247WN@186801|Clostridia,27J26@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_02422	33035.JPJF01000042_gene424	2e-283	775.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3XYUR@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyl_synth,Pribosyltran,Pribosyltran_N
NFNHFNFO_02423	33035.JPJF01000042_gene425	1.39e-221	612.0	COG1484@1|root,COG1484@2|Bacteria,1TPKM@1239|Firmicutes,2483D@186801|Clostridia,3XZ0M@572511|Blautia	186801|Clostridia	L	DNA replication protein	dnaC	-	-	ko:K02315	-	-	-	-	ko00000,ko03032	-	-	-	IstB_IS21
NFNHFNFO_02424	33035.JPJF01000042_gene426	1.44e-238	658.0	COG3935@1|root,COG3935@2|Bacteria,1TPR5@1239|Firmicutes,248E7@186801|Clostridia,3XYKI@572511|Blautia	186801|Clostridia	L	primosome component and related proteins	dnaD	-	-	-	-	-	-	-	-	-	-	-	DnaB_2
NFNHFNFO_02425	33035.JPJF01000042_gene427	0.0	871.0	COG0773@1|root,COG0773@2|Bacteria,1TQ5H@1239|Firmicutes,2484K@186801|Clostridia,3XYHG@572511|Blautia	186801|Clostridia	M	Belongs to the MurCDEF family	murC	-	6.3.2.8	ko:K01924	ko00471,ko00550,ko01100,map00471,map00550,map01100	-	R03193	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NFNHFNFO_02426	33035.JPJF01000042_gene428	6.66e-282	773.0	COG0448@1|root,COG0448@2|Bacteria,1TNZW@1239|Firmicutes,24943@186801|Clostridia,3XZGS@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans	glgC	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NFNHFNFO_02427	33035.JPJF01000042_gene429	1.14e-253	697.0	COG0448@1|root,COG0448@2|Bacteria,1TPZ3@1239|Firmicutes,2482Q@186801|Clostridia,3XZRM@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	glgD	-	2.7.7.27	ko:K00975	ko00500,ko00520,ko01100,ko01110,ko02026,map00500,map00520,map01100,map01110,map02026	M00565	R00948	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,NTP_transferase
NFNHFNFO_02428	33035.JPJF01000042_gene430	3.82e-57	177.0	COG2088@1|root,COG2088@2|Bacteria,1V9ZG@1239|Firmicutes,24MVQ@186801|Clostridia,3Y05I@572511|Blautia	186801|Clostridia	D	Could be involved in septation	spoVG	-	-	ko:K06412	-	-	-	-	ko00000	-	-	-	SpoVG
NFNHFNFO_02429	33035.JPJF01000064_gene3837	1.51e-122	374.0	COG2508@1|root,COG2508@2|Bacteria	2|Bacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NFNHFNFO_02430	33035.JPJF01000100_gene3596	7.21e-266	726.0	COG0407@1|root,COG0407@2|Bacteria,1V9U0@1239|Firmicutes,24MDE@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_02431	33035.JPJF01000100_gene3595	3.31e-121	348.0	COG0523@1|root,COG0523@2|Bacteria,1V755@1239|Firmicutes,24JV0@186801|Clostridia	186801|Clostridia	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
NFNHFNFO_02434	33035.JPJF01000100_gene3592	0.0	874.0	COG0144@1|root,COG3270@1|root,COG0144@2|Bacteria,COG3270@2|Bacteria,1TPGQ@1239|Firmicutes,247N0@186801|Clostridia,3XZ2W@572511|Blautia	186801|Clostridia	J	NOL1 NOP2 sun family protein	rsmF	-	-	-	-	-	-	-	-	-	-	-	Methyltr_RsmB-F,Methyltr_RsmF_N,Methyltranf_PUA,RsmF_methylt_CI
NFNHFNFO_02435	33035.JPJF01000100_gene3591	2.38e-218	607.0	COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,248K0@186801|Clostridia	186801|Clostridia	K	Transcriptional	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_02436	33035.JPJF01000100_gene3590	2.16e-173	489.0	COG0679@1|root,COG0679@2|Bacteria,1TR9W@1239|Firmicutes,24AQF@186801|Clostridia,3XZ37@572511|Blautia	186801|Clostridia	S	Membrane transport protein	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NFNHFNFO_02438	33035.JPJF01000100_gene3589	1.74e-222	651.0	2BZEU@1|root,30VT8@2|Bacteria,1V54M@1239|Firmicutes,24SSI@186801|Clostridia,3XZVW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02439	33035.JPJF01000100_gene3588	6.38e-167	466.0	COG1180@1|root,COG1180@2|Bacteria,1V1GP@1239|Firmicutes,24G76@186801|Clostridia,3XZK7@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	-	-	1.97.1.4	ko:K04069	-	-	R04710	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NFNHFNFO_02441	33035.JPJF01000100_gene3587	6.96e-114	327.0	COG0590@1|root,COG0590@2|Bacteria,1V3HZ@1239|Firmicutes,24JM2@186801|Clostridia,3XZVE@572511|Blautia	186801|Clostridia	FJ	Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2)	tadA	-	3.5.4.33	ko:K11991	-	-	R10223	RC00477	ko00000,ko01000,ko03016	-	-	-	MafB19-deam
NFNHFNFO_02442	33035.JPJF01000100_gene3586	3.01e-192	535.0	COG0646@1|root,COG0646@2|Bacteria,1TPYV@1239|Firmicutes,248JB@186801|Clostridia,3XZSY@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	metH	-	2.1.1.13	ko:K00548	ko00270,ko00450,ko00670,ko01100,ko01110,ko01230,map00270,map00450,map00670,map01100,map01110,map01230	M00017	R00946,R09365	RC00035,RC00113,RC01241	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,Pterin_bind,S-methyl_trans
NFNHFNFO_02443	33035.JPJF01000100_gene3585	3.05e-136	387.0	COG0586@1|root,COG0586@2|Bacteria,1TS2R@1239|Firmicutes,24HX6@186801|Clostridia,3Y0W7@572511|Blautia	186801|Clostridia	S	SNARE associated Golgi protein	-	-	-	-	-	-	-	-	-	-	-	-	SNARE_assoc
NFNHFNFO_02445	33035.JPJF01000100_gene3583	1.62e-256	703.0	COG0205@1|root,COG0205@2|Bacteria,1TPF4@1239|Firmicutes,249AM@186801|Clostridia,3XZ13@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis	pfkA	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NFNHFNFO_02446	33035.JPJF01000100_gene3582	0.0	997.0	COG2812@1|root,COG2812@2|Bacteria,1TPS9@1239|Firmicutes,247J7@186801|Clostridia,3XZM7@572511|Blautia	186801|Clostridia	L	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity	dnaX	-	2.7.7.7	ko:K02343	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNA_pol3_gamma3
NFNHFNFO_02447	33035.JPJF01000100_gene3581	8.04e-72	216.0	COG0718@1|root,COG0718@2|Bacteria,1VA1S@1239|Firmicutes,24MXH@186801|Clostridia,3Y02F@572511|Blautia	186801|Clostridia	L	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection	-	-	-	ko:K09747	-	-	-	-	ko00000	-	-	-	YbaB_DNA_bd
NFNHFNFO_02448	33035.JPJF01000100_gene3580	6.7e-135	382.0	COG0353@1|root,COG0353@2|Bacteria,1TR87@1239|Firmicutes,2487H@186801|Clostridia,3XZEE@572511|Blautia	186801|Clostridia	L	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO	recR	-	-	ko:K06187	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	HHH,RecR,Toprim_4
NFNHFNFO_02449	33035.JPJF01000100_gene3579	6.61e-256	702.0	COG1609@1|root,COG1609@2|Bacteria,1UYY5@1239|Firmicutes,24C8C@186801|Clostridia,3XZ1C@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NFNHFNFO_02450	33035.JPJF01000100_gene3578	4.31e-149	420.0	COG0176@1|root,COG0176@2|Bacteria,1TP4Q@1239|Firmicutes,248KZ@186801|Clostridia,3XYWX@572511|Blautia	186801|Clostridia	H	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway	tal	-	2.2.1.2	ko:K00616	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007	R01827	RC00439,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	TAL_FSA
NFNHFNFO_02451	33035.JPJF01000100_gene3577	1.58e-200	555.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZ3S@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	tktA	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
NFNHFNFO_02452	33035.JPJF01000100_gene3576	5.9e-208	577.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,3XZRN@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	tktB	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
NFNHFNFO_02453	33035.JPJF01000100_gene3575	2.48e-170	475.0	COG1418@1|root,COG1418@2|Bacteria,1V4QX@1239|Firmicutes,24JBS@186801|Clostridia,3Y0A7@572511|Blautia	186801|Clostridia	S	HD superfamily hydrolase	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
NFNHFNFO_02454	1123075.AUDP01000020_gene1539	3.21e-70	220.0	2ADZG@1|root,313RY@2|Bacteria,1V6JT@1239|Firmicutes,24JCA@186801|Clostridia,3WIIG@541000|Ruminococcaceae	186801|Clostridia	S	sporulation protein	yyaC	-	-	-	-	-	-	-	-	-	-	-	DUF1256
NFNHFNFO_02455	33035.JPJF01000100_gene3573	1.02e-236	661.0	COG1388@1|root,COG1388@2|Bacteria,1V4FJ@1239|Firmicutes,24IPI@186801|Clostridia,3XZF7@572511|Blautia	186801|Clostridia	M	Lysin motif	-	-	-	-	-	-	-	-	-	-	-	-	LysM
NFNHFNFO_02456	33035.JPJF01000100_gene3572	2.38e-231	642.0	2C3W5@1|root,2ZBIU@2|Bacteria,1UZRE@1239|Firmicutes,24BHB@186801|Clostridia,3XYH0@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02457	33035.JPJF01000100_gene3571	1.98e-133	380.0	2DMJ6@1|root,32RY3@2|Bacteria,1VBBI@1239|Firmicutes,24SVX@186801|Clostridia,3Y00H@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Colicin_V
NFNHFNFO_02458	33035.JPJF01000100_gene3570	3.92e-225	622.0	COG1609@1|root,COG1609@2|Bacteria,1UM0E@1239|Firmicutes,25B2H@186801|Clostridia,3Y2DY@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_02459	33035.JPJF01000100_gene3569	2.96e-285	780.0	COG1653@1|root,COG1653@2|Bacteria,1TQJE@1239|Firmicutes,2496C@186801|Clostridia,3XZ5U@572511|Blautia	186801|Clostridia	G	ABC transporter periplasmic binding protein YcjN precursor	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02460	33035.JPJF01000100_gene3568	1.52e-157	447.0	COG1175@1|root,COG1175@2|Bacteria,1TQB1@1239|Firmicutes,25C4P@186801|Clostridia,3XZG3@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_02461	33035.JPJF01000100_gene3567	1.65e-180	504.0	COG0395@1|root,COG0395@2|Bacteria,1TR45@1239|Firmicutes,24A3D@186801|Clostridia,3XYY7@572511|Blautia	186801|Clostridia	P	glycine betaine L-proline ABC transporter, permease protein	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_02462	33035.JPJF01000100_gene3566	0.0	1097.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3XZ6T@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	malL	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
NFNHFNFO_02463	537007.BLAHAN_05052	4.4e-136	403.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia,3Y156@572511|Blautia	186801|Clostridia	E	Urocanase C-terminal domain	hutU	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
NFNHFNFO_02464	33035.JPJF01000059_gene3007	2.32e-299	816.0	COG1228@1|root,COG1228@2|Bacteria,1TP2J@1239|Firmicutes,24AGR@186801|Clostridia,3Y1G1@572511|Blautia	186801|Clostridia	Q	Amidohydrolase family	hutI	-	3.5.2.7	ko:K01468	ko00340,ko01100,map00340,map01100	M00045	R02288	RC00683	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
NFNHFNFO_02465	33035.JPJF01000059_gene3008	8.54e-214	590.0	COG3643@1|root,COG3643@2|Bacteria,1TP5T@1239|Firmicutes,24905@186801|Clostridia,3Y0Y3@572511|Blautia	186801|Clostridia	E	Formiminotransferase domain, N-terminal subdomain	ftcD	-	2.1.2.5	ko:K00603	ko00340,ko00670,ko01100,map00340,map00670,map01100	-	R02287,R03189	RC00165,RC00221,RC00223,RC00870	ko00000,ko00001,ko01000	-	-	-	FTCD,FTCD_N
NFNHFNFO_02466	33035.JPJF01000059_gene3009	2.55e-126	362.0	COG3404@1|root,COG3404@2|Bacteria,1V1X8@1239|Firmicutes,24JZM@186801|Clostridia,3Y154@572511|Blautia	186801|Clostridia	E	Formiminotransferase-cyclodeaminase	fchA	-	4.3.1.4	ko:K01746	ko00670,ko01100,map00670,map01100	-	R02302	RC00688	ko00000,ko00001,ko01000	-	-	-	FTCD_C
NFNHFNFO_02467	33035.JPJF01000059_gene3010	7.09e-53	166.0	COG3052@1|root,COG3052@2|Bacteria,1VEZZ@1239|Firmicutes,24QMJ@186801|Clostridia,3Y1SC@572511|Blautia	186801|Clostridia	C	Malonate decarboxylase delta subunit (MdcD)	citD	-	-	ko:K01646	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001	-	-	-	ACP
NFNHFNFO_02468	33035.JPJF01000059_gene3011	2.33e-204	566.0	COG2301@1|root,COG2301@2|Bacteria,1TPDY@1239|Firmicutes,24AIH@186801|Clostridia,3Y0KU@572511|Blautia	186801|Clostridia	G	Belongs to the HpcH HpaI aldolase family	citE	-	4.1.3.34	ko:K01644	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	-	HpcH_HpaI
NFNHFNFO_02469	33035.JPJF01000059_gene3012	0.0	888.0	COG3051@1|root,COG3051@2|Bacteria,1TPN3@1239|Firmicutes,247QD@186801|Clostridia,3Y18V@572511|Blautia	186801|Clostridia	C	Citrate lyase, alpha subunit (CitF)	citF	-	2.8.3.10	ko:K01643	ko02020,map02020	-	R00362	RC00067,RC01118	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19975	CitF
NFNHFNFO_02470	33035.JPJF01000059_gene3013	6.05e-98	285.0	COG2185@1|root,COG2185@2|Bacteria,1V45Q@1239|Firmicutes,24HGC@186801|Clostridia,3Y1IG@572511|Blautia	186801|Clostridia	I	B12 binding domain	mamA	-	5.4.99.1	ko:K01846	ko00630,ko00660,ko01100,ko01200,map00630,map00660,map01100,map01200	M00740	R00262	RC01221	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding
NFNHFNFO_02471	33035.JPJF01000059_gene3014	0.0	889.0	COG0849@1|root,COG0849@2|Bacteria,1TQC5@1239|Firmicutes,24BFJ@186801|Clostridia,3Y1AA@572511|Blautia	186801|Clostridia	D	MutL protein	mutL2	-	-	-	-	-	-	-	-	-	-	-	MutL
NFNHFNFO_02472	33035.JPJF01000059_gene3015	0.0	944.0	COG4865@1|root,COG4865@2|Bacteria,1TS6B@1239|Firmicutes,24AYE@186801|Clostridia,3Y11W@572511|Blautia	186801|Clostridia	E	Methylaspartate mutase E chain (MutE)	glmE	-	5.4.99.1	ko:K19268	ko00630,ko00660,ko01100,ko01200,map00630,map00660,map01100,map01200	M00740	R00262	RC01221	ko00000,ko00001,ko00002,ko01000	-	-	-	Met_asp_mut_E
NFNHFNFO_02473	33035.JPJF01000059_gene3016	4.52e-301	821.0	COG3799@1|root,COG3799@2|Bacteria,1TQ7T@1239|Firmicutes,247VB@186801|Clostridia,3Y17G@572511|Blautia	186801|Clostridia	E	Methylaspartate ammonia-lyase N-terminus	-	-	4.3.1.2	ko:K04835	ko00630,ko00660,ko01100,ko01200,map00630,map00660,map01100,map01200	M00740	R03696	RC00979	ko00000,ko00001,ko00002,ko01000	-	-	-	MAAL_C,MAAL_N
NFNHFNFO_02474	33035.JPJF01000059_gene3017	3.83e-229	630.0	COG0441@1|root,COG0441@2|Bacteria,1TPW5@1239|Firmicutes,24B69@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02475	33035.JPJF01000059_gene3018	1.89e-193	537.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3XZ8S@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
NFNHFNFO_02476	33035.JPJF01000059_gene3019	8.02e-119	340.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,3XZI9@572511|Blautia	186801|Clostridia	C	COG COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
NFNHFNFO_02477	33035.JPJF01000059_gene3021	4.76e-174	489.0	2BZUE@1|root,33RE4@2|Bacteria,1VS46@1239|Firmicutes,259VV@186801|Clostridia,3Y0S0@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02478	33035.JPJF01000059_gene3022	1.18e-156	444.0	COG1237@1|root,COG1237@2|Bacteria,1UWI6@1239|Firmicutes,247K3@186801|Clostridia,3Y1XS@572511|Blautia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	2.5.1.105	ko:K06897	ko00790,map00790	-	R10339	RC00121	ko00000,ko00001,ko01000	-	-	-	Lactamase_B
NFNHFNFO_02479	33035.JPJF01000059_gene3023	3.37e-178	497.0	28NW4@1|root,30Q9J@2|Bacteria,1V4ZJ@1239|Firmicutes,24GHA@186801|Clostridia,3XZZE@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	SseB
NFNHFNFO_02480	33035.JPJF01000059_gene3024	4.49e-190	528.0	COG2159@1|root,COG2159@2|Bacteria,1W7C1@1239|Firmicutes,258X3@186801|Clostridia,3Y255@572511|Blautia	186801|Clostridia	S	Amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_2
NFNHFNFO_02481	33035.JPJF01000059_gene3025	3.07e-196	544.0	COG0613@1|root,COG0613@2|Bacteria,1V46R@1239|Firmicutes,24BEJ@186801|Clostridia,3XZ88@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PHP,PHP_C
NFNHFNFO_02482	33035.JPJF01000059_gene3026	4.04e-302	825.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3XZMY@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,Homoserine_dh,NAD_binding_3
NFNHFNFO_02483	33035.JPJF01000059_gene3027	6.35e-249	687.0	COG0013@1|root,COG0013@2|Bacteria,1TSBZ@1239|Firmicutes,249VN@186801|Clostridia,3XZ3U@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	alaXL	-	6.1.1.7	ko:K01872	ko00970,map00970	M00359,M00360	R03038	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DHHA1,tRNA-synt_2c,tRNA_SAD
NFNHFNFO_02484	33035.JPJF01000059_gene3028	5.3e-141	406.0	COG1735@1|root,COG1735@2|Bacteria,1TS8I@1239|Firmicutes,249N0@186801|Clostridia,3Y0WE@572511|Blautia	186801|Clostridia	S	Phosphotriesterase family	-	-	-	ko:K07048	-	-	-	-	ko00000	-	-	-	PTE
NFNHFNFO_02485	33035.JPJF01000013_gene4583	1.98e-75	236.0	COG5464@1|root,COG5464@2|Bacteria,1V3CA@1239|Firmicutes,24H4R@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
NFNHFNFO_02486	33035.JPJF01000059_gene3031	0.0	1088.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247Q9@186801|Clostridia,3XZ7N@572511|Blautia	186801|Clostridia	S	COG COG0488 ATPase components of ABC transporters with duplicated ATPase domains	yfmR	-	-	ko:K15738	-	-	-	-	ko00000,ko02000	3.A.1.120.6	-	-	ABC_tran,ABC_tran_CTD,ABC_tran_Xtn
NFNHFNFO_02487	33035.JPJF01000059_gene3032	7.02e-199	553.0	arCOG12964@1|root,2Z7HP@2|Bacteria,1UZIT@1239|Firmicutes,24G0N@186801|Clostridia,3Y1MB@572511|Blautia	186801|Clostridia	S	Tocopherol cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Tocopherol_cycl
NFNHFNFO_02488	33035.JPJF01000059_gene3033	1.24e-77	232.0	COG1733@1|root,COG1733@2|Bacteria,1VCB0@1239|Firmicutes,25CM9@186801|Clostridia	186801|Clostridia	K	HxlR-like helix-turn-helix	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
NFNHFNFO_02489	33035.JPJF01000059_gene3034	0.0	1354.0	COG0466@1|root,COG0466@2|Bacteria,1TNYG@1239|Firmicutes,247SH@186801|Clostridia,3XYJU@572511|Blautia	186801|Clostridia	O	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner	lon	-	3.4.21.53	ko:K01338	ko04112,map04112	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	AAA,LON_substr_bdg,Lon_C
NFNHFNFO_02490	33035.JPJF01000059_gene3036	0.0	1492.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3XZ9E@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	ko:K12952	-	-	-	-	ko00000,ko01000	3.A.3.23	-	-	E1-E2_ATPase,Hydrolase
NFNHFNFO_02491	457421.CBFG_03911	7.81e-116	351.0	COG2207@1|root,COG2207@2|Bacteria,1V28B@1239|Firmicutes,24GF0@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
NFNHFNFO_02492	742733.HMPREF9469_05529	1.34e-117	345.0	COG0546@1|root,COG0546@2|Bacteria,1V1RB@1239|Firmicutes,2487B@186801|Clostridia,21YYT@1506553|Lachnoclostridium	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2
NFNHFNFO_02493	457421.CBFG_03913	0.0	940.0	COG1472@1|root,COG1472@2|Bacteria,1TP63@1239|Firmicutes,24YIP@186801|Clostridia,268GX@186813|unclassified Clostridiales	186801|Clostridia	G	Glycosyl hydrolase family 3 N terminal domain	-	-	3.2.1.52	ko:K01207	ko00520,ko00531,ko01100,ko01501,map00520,map00531,map01100,map01501	M00628	R00022,R05963,R07809,R07810,R10831	RC00049	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_3
NFNHFNFO_02494	742733.HMPREF9469_05527	9.54e-236	660.0	COG2211@1|root,COG2211@2|Bacteria,1TRYR@1239|Firmicutes,25C8G@186801|Clostridia,22484@1506553|Lachnoclostridium	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_02495	478749.BRYFOR_06575	1.19e-250	692.0	COG0493@1|root,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia	186801|Clostridia	C	'glutamate synthase	-	-	1.4.1.13,1.4.1.14	ko:K00266	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
NFNHFNFO_02496	755731.Clo1100_0972	3.23e-131	382.0	2DB8K@1|root,2Z7S1@2|Bacteria,1TRA1@1239|Firmicutes,24886@186801|Clostridia,36FHZ@31979|Clostridiaceae	186801|Clostridia	H	Streptomycin adenylyltransferase	-	-	-	ko:K05593	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Adenyl_transf
NFNHFNFO_02497	33035.JPJF01000059_gene3038	1.44e-140	400.0	2BD2V@1|root,326QD@2|Bacteria,1USKQ@1239|Firmicutes,2584W@186801|Clostridia,3Y24G@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02498	33035.JPJF01000059_gene3039	4.51e-56	175.0	COG4430@1|root,COG4430@2|Bacteria,1VA6D@1239|Firmicutes,24N9F@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF1905)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1905,OmdA
NFNHFNFO_02499	33035.JPJF01000059_gene3040	5.32e-163	461.0	COG5464@1|root,COG5464@2|Bacteria,1V394@1239|Firmicutes,24GXK@186801|Clostridia,3Y2CV@572511|Blautia	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NFNHFNFO_02500	33035.JPJF01000059_gene3041	0.0	1065.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia	186801|Clostridia	E	Family 5	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NFNHFNFO_02501	33035.JPJF01000059_gene3042	1.67e-207	577.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3Y02S@572511|Blautia	186801|Clostridia	EP	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NFNHFNFO_02502	33035.JPJF01000059_gene3043	3.7e-203	563.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZYG@572511|Blautia	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
NFNHFNFO_02503	33035.JPJF01000059_gene3044	2.57e-224	619.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3XZ1P@572511|Blautia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K02031,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NFNHFNFO_02504	33035.JPJF01000059_gene3045	2.16e-238	655.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3XZ61@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NFNHFNFO_02505	33035.JPJF01000059_gene3049	0.0	1792.0	COG0841@1|root,COG0841@2|Bacteria,1TQ03@1239|Firmicutes,2491S@186801|Clostridia	186801|Clostridia	V	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family	czcA	-	-	ko:K03296	-	-	-	-	ko00000	2.A.6.2	-	-	ACR_tran
NFNHFNFO_02506	33035.JPJF01000059_gene3050	5.51e-122	350.0	COG1309@1|root,COG1309@2|Bacteria,1VG7Q@1239|Firmicutes,24RQP@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_02507	33035.JPJF01000059_gene3051	1.18e-292	799.0	COG0205@1|root,COG0205@2|Bacteria,1TRJQ@1239|Firmicutes,247IV@186801|Clostridia,3XYJB@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions	pfp	-	2.7.1.11,2.7.1.90	ko:K21071	ko00010,ko00030,ko00051,ko00052,ko00680,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00680,map01100,map01110,map01120,map01130	-	R00756,R00764,R02073,R03236,R04779	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PFK
NFNHFNFO_02508	33035.JPJF01000059_gene3052	0.0	936.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3XZBZ@572511|Blautia	186801|Clostridia	E	Orn Lys Arg decarboxylase, major domain protein	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
NFNHFNFO_02509	500632.CLONEX_02169	4.77e-186	519.0	COG0421@1|root,COG0421@2|Bacteria,1TPG5@1239|Firmicutes,24827@186801|Clostridia	186801|Clostridia	H	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine	speE	-	2.5.1.16	ko:K00797	ko00270,ko00330,ko00410,ko00480,ko01100,map00270,map00330,map00410,map00480,map01100	M00034,M00133	R01920,R02869,R08359	RC00021,RC00053	ko00000,ko00001,ko00002,ko01000	-	-	-	Spermine_synt_N,Spermine_synth
NFNHFNFO_02510	33035.JPJF01000059_gene3055	2.04e-191	532.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,2493V@186801|Clostridia,3XYTI@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	speB	-	3.5.3.11	ko:K01480	ko00330,ko01100,map00330,map01100	M00133	R01157	RC00024,RC00329	ko00000,ko00001,ko00002,ko01000	-	-	-	Arginase
NFNHFNFO_02511	33035.JPJF01000059_gene3056	4.44e-293	799.0	COG1748@1|root,COG1748@2|Bacteria,1TQTN@1239|Firmicutes,24AHW@186801|Clostridia,3XYN8@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	LYS1	-	1.5.1.7	ko:K00290	ko00300,ko00310,ko01100,ko01110,ko01130,ko01230,map00300,map00310,map01100,map01110,map01130,map01230	M00030,M00032	R00715	RC00217,RC01532	ko00000,ko00001,ko00002,ko01000	-	-	-	Sacchrp_dh_C,Sacchrp_dh_NADP
NFNHFNFO_02512	33035.JPJF01000059_gene3057	5.69e-260	713.0	COG0019@1|root,COG0019@2|Bacteria,1TPQI@1239|Firmicutes,248NH@186801|Clostridia,3XYIP@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	nspC	-	4.1.1.96	ko:K13747	ko00330,ko01100,map00330,map01100	-	R09081,R09082	RC00299	ko00000,ko00001,ko01000	-	-	-	Orn_DAP_Arg_deC
NFNHFNFO_02513	33035.JPJF01000059_gene3063	4.26e-212	587.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3XZ5J@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
NFNHFNFO_02514	33035.JPJF01000059_gene3065	1.68e-303	830.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3Y18Z@572511|Blautia	186801|Clostridia	E	Sodium:alanine symporter family	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NFNHFNFO_02515	1235798.C817_02821	1.2e-157	466.0	COG1672@1|root,COG1672@2|Bacteria,1TPQR@1239|Firmicutes,24AIK@186801|Clostridia	186801|Clostridia	S	PFAM Archaeal ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,AAA_35,PDDEXK_3
NFNHFNFO_02516	33035.JPJF01000059_gene3066	3.01e-223	615.0	COG4189@1|root,COG4189@2|Bacteria,1TPGD@1239|Firmicutes,248UW@186801|Clostridia	186801|Clostridia	K	regulatory protein, arsR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
NFNHFNFO_02518	33035.JPJF01000011_gene1369	9.26e-301	822.0	COG2182@1|root,COG2182@2|Bacteria,1TPHN@1239|Firmicutes,24CSV@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
NFNHFNFO_02519	33035.JPJF01000011_gene1368	2.07e-206	572.0	COG1175@1|root,COG1175@2|Bacteria,1UPAZ@1239|Firmicutes,24BD1@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_02520	33035.JPJF01000011_gene1367	6.07e-188	523.0	COG0395@1|root,COG0395@2|Bacteria,1TSUB@1239|Firmicutes,24983@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_02521	33035.JPJF01000011_gene1366	0.0	1176.0	COG3250@1|root,COG3250@2|Bacteria,1TQAM@1239|Firmicutes,248XS@186801|Clostridia,3Y0FZ@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFNHFNFO_02522	33035.JPJF01000011_gene1365	0.0	907.0	COG3263@1|root,COG3263@2|Bacteria,1TQPJ@1239|Firmicutes,2486W@186801|Clostridia,3XYNK@572511|Blautia	186801|Clostridia	P	Sodium/hydrogen exchanger family	-	-	-	ko:K11105	-	-	-	-	ko00000,ko02000	2.A.36.6	-	-	Na_H_Exchanger,TrkA_C
NFNHFNFO_02523	33035.JPJF01000011_gene1364	2.5e-177	495.0	COG2820@1|root,COG2820@2|Bacteria,1TSEU@1239|Firmicutes,25E2U@186801|Clostridia,3XZ3Q@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
NFNHFNFO_02524	33035.JPJF01000011_gene1363	2.22e-278	762.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,3XYUY@572511|Blautia	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08920	Metalloenzyme
NFNHFNFO_02525	33035.JPJF01000011_gene1362	5.15e-189	529.0	COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,247KD@186801|Clostridia,3XYH8@572511|Blautia	186801|Clostridia	F	Adenosine/AMP deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS13960	A_deaminase
NFNHFNFO_02526	33035.JPJF01000011_gene1361	2.34e-99	293.0	COG1309@1|root,COG1309@2|Bacteria,1V7DY@1239|Firmicutes,25DSB@186801|Clostridia	186801|Clostridia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
NFNHFNFO_02527	33035.JPJF01000011_gene1360	4.29e-282	776.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia,3Y18H@572511|Blautia	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_02528	742740.HMPREF9474_01942	1.11e-135	407.0	COG4565@1|root,COG4565@2|Bacteria,1V2PC@1239|Firmicutes,24GSU@186801|Clostridia,22413@1506553|Lachnoclostridium	186801|Clostridia	KT	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02529	33035.JPJF01000104_gene2585	6.23e-105	314.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia,3XYUX@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
NFNHFNFO_02530	33035.JPJF01000015_gene4970	1.65e-61	190.0	COG0221@1|root,COG0221@2|Bacteria,1VB6Q@1239|Firmicutes,24NZI@186801|Clostridia	186801|Clostridia	C	Inorganic pyrophosphatase	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	NUDIX,Pyrophosphatase
NFNHFNFO_02531	445974.CLORAM_00226	2.75e-252	696.0	COG0381@1|root,COG0381@2|Bacteria,1TQZT@1239|Firmicutes,3VNR8@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location Cytoplasmic, score 8.87	-	-	5.1.3.14	ko:K01791	ko00520,ko01100,ko05111,map00520,map01100,map05111	M00362	R00420	RC00290	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Epimerase_2
NFNHFNFO_02532	742735.HMPREF9467_00474	2.05e-239	664.0	COG0451@1|root,COG1898@1|root,COG0451@2|Bacteria,COG1898@2|Bacteria,1TQBB@1239|Firmicutes,2486Z@186801|Clostridia,221M5@1506553|Lachnoclostridium	186801|Clostridia	GM	NAD dependent epimerase/dehydratase family	-	-	1.1.1.367	ko:K19068	-	-	-	-	ko00000,ko01000	-	-	-	Epimerase
NFNHFNFO_02533	742765.HMPREF9457_02827	3.74e-199	557.0	COG1086@1|root,COG1086@2|Bacteria,1TPTC@1239|Firmicutes,247YC@186801|Clostridia,27W24@189330|Dorea	186801|Clostridia	M	Polysaccharide biosynthesis protein C-terminal	capD	-	5.1.3.2	ko:K17716	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00362	R00291	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Polysacc_syn_2C,Polysacc_synt_2
NFNHFNFO_02535	666686.B1NLA3E_20900	1.19e-37	143.0	COG2244@1|root,COG2244@2|Bacteria,1V43Q@1239|Firmicutes,4HKYY@91061|Bacilli	91061|Bacilli	S	polysaccharide biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02536	500632.CLONEX_00178	1.51e-64	204.0	COG0110@1|root,COG0110@2|Bacteria,1TT21@1239|Firmicutes,24CCH@186801|Clostridia	186801|Clostridia	M	Bacterial transferase hexapeptide	wbpD	-	2.3.1.201	ko:K13018	ko00520,map00520	-	R10100	RC00004,RC00166	ko00000,ko00001,ko01000,ko01005	-	-	-	Hexapep,Hexapep_2
NFNHFNFO_02537	888727.HMPREF9092_0279	2.25e-214	597.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia,3WD4E@538999|Clostridiales incertae sedis	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	1.1.1.335	ko:K13020	ko00520,map00520	-	R10140	RC00182	ko00000,ko00001,ko01000,ko01005	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_02538	1280694.AUJQ01000004_gene517	2.81e-172	493.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,3NI4C@46205|Pseudobutyrivibrio	186801|Clostridia	M	Cys/Met metabolism PLP-dependent enzyme	degT1	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
NFNHFNFO_02539	1280685.AUKC01000003_gene2818	1.14e-173	501.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,25B1W@186801|Clostridia,4BWKK@830|Butyrivibrio	186801|Clostridia	M	UDP binding domain	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_3,UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
NFNHFNFO_02540	1235790.C805_00497	1.51e-96	300.0	COG0438@1|root,COG0438@2|Bacteria,1V0A7@1239|Firmicutes,24CHK@186801|Clostridia	186801|Clostridia	M	transferase activity, transferring glycosyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_trans_1_4,Glyco_transf_4,Glycos_transf_1
NFNHFNFO_02542	1286171.EAL2_c20120	9.12e-55	180.0	COG0110@1|root,COG0110@2|Bacteria,1TPKX@1239|Firmicutes,249X2@186801|Clostridia,25VVT@186806|Eubacteriaceae	186801|Clostridia	S	Bacterial transferase hexapeptide (six repeats)	-	-	-	ko:K18234	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Hexapep,Hexapep_2
NFNHFNFO_02543	742735.HMPREF9467_00464	6.71e-113	343.0	COG0438@1|root,COG0438@2|Bacteria,1UTQH@1239|Firmicutes,24BT3@186801|Clostridia,221F4@1506553|Lachnoclostridium	186801|Clostridia	M	Glycosyl transferases group 1	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_transf_4,Glycos_transf_1
NFNHFNFO_02544	457421.CBFG_01777	3.31e-160	463.0	COG0151@1|root,COG0151@2|Bacteria,1TRZ2@1239|Firmicutes,2497Y@186801|Clostridia	186801|Clostridia	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4,GARS_A
NFNHFNFO_02545	883110.HMPREF9260_00323	9.35e-84	254.0	COG2148@1|root,COG2148@2|Bacteria,1TQX9@1239|Firmicutes,4HAF1@91061|Bacilli,27EXS@186827|Aerococcaceae	91061|Bacilli	M	Bacterial sugar transferase	capM	-	-	ko:K13012	-	-	-	-	ko00000,ko01005	-	-	-	Bac_transf
NFNHFNFO_02546	655811.HMPREF0078_1433	1.6e-180	509.0	COG0451@1|root,COG0451@2|Bacteria,1V830@1239|Firmicutes,24BKX@186801|Clostridia	186801|Clostridia	M	GDP-mannose 4,6 dehydratase	-	-	5.1.3.2	ko:K01784	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00361,M00362,M00632	R00291,R02984	RC00289	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
NFNHFNFO_02547	742733.HMPREF9469_02001	3.64e-231	644.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,21Y82@1506553|Lachnoclostridium	186801|Clostridia	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
NFNHFNFO_02548	33035.JPJF01000042_gene362	0.0	1266.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,3XYZJ@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
NFNHFNFO_02549	33035.JPJF01000042_gene361	5.21e-162	466.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24EJK@186801|Clostridia,3Y163@572511|Blautia	186801|Clostridia	L	Putative transposase DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
NFNHFNFO_02550	1195236.CTER_4237	9.78e-313	884.0	COG3250@1|root,COG3250@2|Bacteria,1VSYK@1239|Firmicutes,24D78@186801|Clostridia,3WSA4@541000|Ruminococcaceae	186801|Clostridia	G	Glycosyl hydrolases family 2, TIM barrel domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C
NFNHFNFO_02551	1195236.CTER_4238	0.0	931.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,25BZC@186801|Clostridia,3WSA6@541000|Ruminococcaceae	1239|Firmicutes	G	Glycosyl hydrolases family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C
NFNHFNFO_02552	1304866.K413DRAFT_4040	3.84e-163	463.0	COG0667@1|root,COG0667@2|Bacteria,1UKPC@1239|Firmicutes,24F85@186801|Clostridia	186801|Clostridia	C	PFAM Aldo keto reductase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NFNHFNFO_02553	1195236.CTER_4240	1.46e-300	853.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,25BZC@186801|Clostridia,3WSA6@541000|Ruminococcaceae	1239|Firmicutes	G	Glycosyl hydrolases family 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C
NFNHFNFO_02554	1195236.CTER_4241	1.42e-136	393.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,3WH4R@541000|Ruminococcaceae	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026,ko:K10242	ko02010,map02010	M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23	-	-	BPD_transp_1
NFNHFNFO_02555	1195236.CTER_4242	3e-152	435.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia,3WIYD@541000|Ruminococcaceae	186801|Clostridia	P	ABC-type sugar transport systems permease components	-	-	-	ko:K02025,ko:K10189,ko:K10241	ko02010,map02010	M00199,M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23,3.A.1.1.4	-	-	BPD_transp_1
NFNHFNFO_02556	1195236.CTER_4243	6.06e-221	620.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,3WIK9@541000|Ruminococcaceae	186801|Clostridia	G	PFAM Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02557	1195236.CTER_4244	1.22e-34	134.0	COG2972@1|root,COG2972@2|Bacteria,1U0TK@1239|Firmicutes,25KJU@186801|Clostridia,3WPTI@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NFNHFNFO_02558	1195236.CTER_4244	5.93e-110	343.0	COG2972@1|root,COG2972@2|Bacteria,1U0TK@1239|Firmicutes,25KJU@186801|Clostridia,3WPTI@541000|Ruminococcaceae	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NFNHFNFO_02559	1195236.CTER_4245	2.02e-97	310.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TPDP@1239|Firmicutes,24A5I@186801|Clostridia	186801|Clostridia	T	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_02560	33035.JPJF01000015_gene4974	1.77e-115	332.0	COG1268@1|root,COG1268@2|Bacteria,1VAY6@1239|Firmicutes,24HPU@186801|Clostridia,3Y025@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	bioY	-	-	ko:K03523	ko02010,map02010	M00581,M00582	-	-	ko00000,ko00001,ko00002,ko02000	2.A.88.1,2.A.88.2	-	-	BioY
NFNHFNFO_02561	428126.CLOSPI_00221	3.84e-58	192.0	COG5061@1|root,COG5061@2|Bacteria,1VF12@1239|Firmicutes	1239|Firmicutes	OU	Protein of unknown function (DUF3307)	satE	-	-	-	-	-	-	-	-	-	-	-	DUF3307
NFNHFNFO_02562	1232453.BAIF02000024_gene4059	2.42e-79	244.0	2BUWD@1|root,32Q8G@2|Bacteria,1UHQJ@1239|Firmicutes,24F32@186801|Clostridia	186801|Clostridia	S	SatD family (SatD)	-	-	-	-	-	-	-	-	-	-	-	-	SatD
NFNHFNFO_02563	33035.JPJF01000015_gene4986	1.02e-50	161.0	COG1918@1|root,COG1918@2|Bacteria,1TTUK@1239|Firmicutes,25P4D@186801|Clostridia,3Y241@572511|Blautia	186801|Clostridia	P	FeoA	-	-	-	ko:K04758	-	-	-	-	ko00000,ko02000	-	-	-	FeoA
NFNHFNFO_02564	33035.JPJF01000015_gene4987	1.65e-232	641.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3Y0XN@572511|Blautia	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB2	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
NFNHFNFO_02565	33035.JPJF01000015_gene4988	3.71e-314	864.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,3XZS5@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NFNHFNFO_02567	1235802.C823_04050	5.35e-112	324.0	COG3506@1|root,COG3506@2|Bacteria,1TSXY@1239|Firmicutes,2484H@186801|Clostridia,25Y9J@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF1349)	-	-	-	ko:K09702	-	-	-	-	ko00000	-	-	-	DUF1349
NFNHFNFO_02568	33035.JPJF01000015_gene4990	5.38e-93	272.0	COG0295@1|root,COG0295@2|Bacteria,1V6IP@1239|Firmicutes,24JEM@186801|Clostridia,3Y030@572511|Blautia	186801|Clostridia	F	This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis	cdd	-	3.5.4.5	ko:K01489	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01878,R02485,R08221	RC00074,RC00514	ko00000,ko00001,ko01000	-	-	-	dCMP_cyt_deam_1,dCMP_cyt_deam_2
NFNHFNFO_02569	33035.JPJF01000015_gene4991	3.97e-143	405.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,3XZXA@572511|Blautia	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
NFNHFNFO_02570	33035.JPJF01000015_gene4992	2.2e-274	752.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,3XYUY@572511|Blautia	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS08920	Metalloenzyme
NFNHFNFO_02571	33035.JPJF01000015_gene4993	7.62e-249	684.0	COG1744@1|root,COG1744@2|Bacteria,1TPEU@1239|Firmicutes,248QT@186801|Clostridia,3XZCF@572511|Blautia	186801|Clostridia	S	ABC transporter substrate-binding protein PnrA-like	tmpC	-	-	ko:K07335	-	-	-	-	ko00000	-	-	-	Bmp
NFNHFNFO_02572	33035.JPJF01000015_gene4994	3.11e-213	591.0	COG1079@1|root,COG1079@2|Bacteria,1TP8Y@1239|Firmicutes,2486N@186801|Clostridia,3XYSQ@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NFNHFNFO_02573	33035.JPJF01000015_gene4995	2.97e-246	678.0	COG4603@1|root,COG4603@2|Bacteria,1TP1F@1239|Firmicutes,2494C@186801|Clostridia,3XZMU@572511|Blautia	186801|Clostridia	P	Branched-chain amino acid transport system / permease component	-	-	-	ko:K02057	-	M00221	-	-	ko00000,ko00002,ko02000	3.A.1.2	-	-	BPD_transp_2
NFNHFNFO_02574	33035.JPJF01000015_gene4996	0.0	967.0	COG3845@1|root,COG3845@2|Bacteria,1UYQA@1239|Firmicutes,24XN8@186801|Clostridia,3XYKD@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	3.6.3.17	ko:K02056	-	M00221	-	-	ko00000,ko00002,ko01000,ko02000	3.A.1.2	-	-	ABC_tran
NFNHFNFO_02575	33035.JPJF01000015_gene4997	5.66e-180	501.0	COG2820@1|root,COG2820@2|Bacteria,1TSEU@1239|Firmicutes,25E2U@186801|Clostridia,3XZ3Q@572511|Blautia	186801|Clostridia	F	Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis	udp	-	2.4.2.3	ko:K00757	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R01876,R02484,R08229	RC00063	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
NFNHFNFO_02576	33035.JPJF01000015_gene4998	3.02e-164	461.0	COG2188@1|root,COG2188@2|Bacteria,1V4G6@1239|Firmicutes,249MD@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR,UTRA
NFNHFNFO_02577	33035.JPJF01000015_gene5000	0.0	1501.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,24A10@186801|Clostridia,3Y0MS@572511|Blautia	186801|Clostridia	G	COG COG1501 Alpha-glucosidases, family 31 of glycosyl hydrolases	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	Gal_mutarotas_2,Glyco_hydro_31
NFNHFNFO_02579	33035.JPJF01000119_gene1827	4.63e-173	486.0	COG4974@1|root,COG4974@2|Bacteria,1TY7M@1239|Firmicutes,24BN9@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	ko:K04763	-	-	-	-	ko00000,ko03036	-	-	-	Phage_int_SAM_1,Phage_int_SAM_4,Phage_integrase
NFNHFNFO_02580	33035.JPJF01000119_gene1826	1.96e-149	426.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3Y0XN@572511|Blautia	186801|Clostridia	P	transporter of a GTP-driven Fe(2 ) uptake system	feoB2	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
NFNHFNFO_02581	33035.JPJF01000119_gene1825	2.75e-185	518.0	COG0583@1|root,COG0583@2|Bacteria,1TP9T@1239|Firmicutes,24AYF@186801|Clostridia,3Y06U@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_02582	1226325.HMPREF1548_01171	1.66e-94	284.0	COG0384@1|root,COG0384@2|Bacteria,1TPPX@1239|Firmicutes,247ZD@186801|Clostridia,36DN6@31979|Clostridiaceae	186801|Clostridia	S	Phenazine biosynthesis protein, PhzF family	-	-	5.3.3.17	ko:K06998	ko00405,ko01130,ko02024,map00405,map01130,map02024	M00835	-	-	ko00000,ko00001,ko00002,ko01000	-	-	-	PhzC-PhzF
NFNHFNFO_02583	33035.JPJF01000119_gene1823	1.82e-95	289.0	COG0697@1|root,COG0697@2|Bacteria,1V2EI@1239|Firmicutes,24GU6@186801|Clostridia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_02584	537007.BLAHAN_06708	2.3e-237	664.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NFNHFNFO_02585	33035.JPJF01000097_gene1732	1.1e-255	702.0	COG0686@1|root,COG0686@2|Bacteria,1TNZ5@1239|Firmicutes,2489D@186801|Clostridia,3Y0R9@572511|Blautia	186801|Clostridia	C	Alanine dehydrogenase/PNT, N-terminal domain	ald	-	1.4.1.1	ko:K00259	ko00250,ko00430,ko01100,map00250,map00430,map01100	-	R00396	RC00008	ko00000,ko00001,ko01000	-	-	-	AlaDh_PNT_C,AlaDh_PNT_N
NFNHFNFO_02586	33035.JPJF01000097_gene1731	7.09e-191	531.0	COG1737@1|root,COG1737@2|Bacteria,1UM7F@1239|Firmicutes,24B91@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix domain, rpiR family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_6,SIS
NFNHFNFO_02587	742733.HMPREF9469_00612	0.0	1169.0	COG0642@1|root,COG0642@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,21Z4X@1506553|Lachnoclostridium	186801|Clostridia	T	Psort location CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
NFNHFNFO_02588	33035.JPJF01000051_gene769	4.47e-172	499.0	COG5598@1|root,COG5598@2|Bacteria,1UY21@1239|Firmicutes,248BQ@186801|Clostridia	186801|Clostridia	H	PFAM Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
NFNHFNFO_02590	33035.JPJF01000072_gene4349	4.5e-160	449.0	COG0204@1|root,COG0204@2|Bacteria,1TTPK@1239|Firmicutes,24B6K@186801|Clostridia,3XYHT@572511|Blautia	186801|Clostridia	I	Psort location Cytoplasmic, score 8.87	-	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
NFNHFNFO_02591	33035.JPJF01000072_gene4350	4.17e-112	324.0	2BWC2@1|root,33RSK@2|Bacteria,1VS2M@1239|Firmicutes,24YI2@186801|Clostridia,3Y093@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02592	33035.JPJF01000072_gene4351	0.0	1588.0	COG0188@1|root,COG0188@2|Bacteria,1TP2Z@1239|Firmicutes,2482G@186801|Clostridia,3XZN8@572511|Blautia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrA	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
NFNHFNFO_02593	33035.JPJF01000072_gene4352	0.0	1239.0	COG0187@1|root,COG0187@2|Bacteria,1TQ0R@1239|Firmicutes,248AV@186801|Clostridia,3XYYE@572511|Blautia	186801|Clostridia	L	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner	gyrB	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
NFNHFNFO_02594	33035.JPJF01000072_gene4353	7.39e-253	694.0	COG1195@1|root,COG1195@2|Bacteria,1TP9U@1239|Firmicutes,247KY@186801|Clostridia,3XZEV@572511|Blautia	186801|Clostridia	L	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP	recF	-	-	ko:K03629	ko03440,map03440	-	-	-	ko00000,ko00001,ko03400	-	-	-	SMC_N
NFNHFNFO_02595	33035.JPJF01000072_gene4354	1.81e-41	136.0	COG2501@1|root,COG2501@2|Bacteria,1VYQT@1239|Firmicutes,24QZU@186801|Clostridia,3Y0NB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yaaA	-	-	ko:K14761	-	-	-	-	ko00000,ko03009	-	-	-	S4_2
NFNHFNFO_02596	33035.JPJF01000072_gene4355	8.43e-249	684.0	COG0592@1|root,COG0592@2|Bacteria,1TQ7J@1239|Firmicutes,248EG@186801|Clostridia,3XZ49@572511|Blautia	186801|Clostridia	L	Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria	dnaN	-	2.7.7.7	ko:K02338	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_beta,DNA_pol3_beta_2,DNA_pol3_beta_3
NFNHFNFO_02597	33035.JPJF01000072_gene4356	8.38e-307	838.0	COG0593@1|root,COG0593@2|Bacteria,1TPV7@1239|Firmicutes,2490S@186801|Clostridia,3XYQ0@572511|Blautia	186801|Clostridia	L	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids	dnaA	-	-	ko:K02313	ko02020,ko04112,map02020,map04112	-	-	-	ko00000,ko00001,ko03032,ko03036	-	-	-	Bac_DnaA,Bac_DnaA_C,DnaA_N
NFNHFNFO_02598	1235793.C809_01737	4.47e-18	75.5	COG0230@1|root,COG0230@2|Bacteria,1VK90@1239|Firmicutes,24UGN@186801|Clostridia,27QHB@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Ribosomal protein L34	rpmH	-	-	ko:K02914	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L34
NFNHFNFO_02599	537007.BLAHAN_05902	1.24e-63	196.0	COG0594@1|root,COG0594@2|Bacteria,1VA78@1239|Firmicutes,24QK5@186801|Clostridia,3Y06S@572511|Blautia	186801|Clostridia	J	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme	rnpA	-	3.1.26.5	ko:K03536	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Ribonuclease_P
NFNHFNFO_02600	33035.JPJF01000072_gene4358	1.31e-283	777.0	COG0706@1|root,COG0706@2|Bacteria,1TQ0J@1239|Firmicutes,247V9@186801|Clostridia,3XZCQ@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	yidC	-	-	ko:K03217	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044,ko03029	2.A.9	-	-	60KD_IMP
NFNHFNFO_02601	33035.JPJF01000072_gene4359	1e-151	432.0	COG1847@1|root,COG1847@2|Bacteria,1V3IN@1239|Firmicutes,249EA@186801|Clostridia,3XZCW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	jag	-	-	ko:K06346	-	-	-	-	ko00000	-	-	-	Jag_N,KH_4,R3H
NFNHFNFO_02602	33035.JPJF01000072_gene4360	2.04e-295	810.0	COG0486@1|root,COG0486@2|Bacteria,1TPJF@1239|Firmicutes,248A9@186801|Clostridia,3XYJS@572511|Blautia	186801|Clostridia	S	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34	mnmE	-	-	ko:K03650	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko01000,ko03016	-	-	-	MMR_HSR1,MnmE_helical,TrmE_N
NFNHFNFO_02603	33035.JPJF01000072_gene4361	0.0	1191.0	COG0445@1|root,COG0445@2|Bacteria,1TQ4B@1239|Firmicutes,247U2@186801|Clostridia,3XYJA@572511|Blautia	186801|Clostridia	D	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34	gidA	-	-	ko:K03495	-	-	R08701	RC00053,RC00209,RC00870	ko00000,ko03016,ko03036	-	-	-	GIDA,GIDA_assoc
NFNHFNFO_02604	33035.JPJF01000072_gene4362	7.83e-161	452.0	COG0357@1|root,COG0357@2|Bacteria,1TPBT@1239|Firmicutes,247WM@186801|Clostridia,3XYIZ@572511|Blautia	186801|Clostridia	H	Specifically methylates the N7 position of a guanine in 16S rRNA	rsmG	-	2.1.1.170	ko:K03501	-	-	-	-	ko00000,ko01000,ko03009,ko03036	-	-	-	GidB
NFNHFNFO_02605	33035.JPJF01000072_gene4363	2.52e-205	568.0	COG0714@1|root,COG0714@2|Bacteria,1TQJA@1239|Firmicutes,249C6@186801|Clostridia,3Y1A2@572511|Blautia	186801|Clostridia	S	ATPase family associated with various cellular activities (AAA)	-	-	-	-	-	-	-	-	-	-	-	-	AAA_5
NFNHFNFO_02606	33035.JPJF01000072_gene4364	0.0	1042.0	COG4548@1|root,COG4548@2|Bacteria,1TS8V@1239|Firmicutes,249FH@186801|Clostridia,3Y1CD@572511|Blautia	186801|Clostridia	P	von Willebrand factor (vWF) type A domain	-	-	-	-	-	-	-	-	-	-	-	-	CobT_C
NFNHFNFO_02607	33035.JPJF01000072_gene4365	4.55e-111	321.0	2DNG8@1|root,32XC4@2|Bacteria,1VAW6@1239|Firmicutes,24QFT@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02608	33035.JPJF01000072_gene4366	1.32e-73	221.0	COG3695@1|root,COG3695@2|Bacteria,1VC8H@1239|Firmicutes,24N86@186801|Clostridia	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	ko:K07443	-	-	-	-	ko00000	-	-	-	DNA_binding_1
NFNHFNFO_02609	33035.JPJF01000072_gene4367	1.12e-216	599.0	COG1131@1|root,COG1131@2|Bacteria,1TQUS@1239|Firmicutes,25AZ1@186801|Clostridia,3XZPU@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_02610	33035.JPJF01000072_gene4368	2.22e-179	502.0	COG1277@1|root,COG1277@2|Bacteria,1UZXS@1239|Firmicutes,248ME@186801|Clostridia,3XYVG@572511|Blautia	186801|Clostridia	N	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane,ABC2_membrane_2,ABC2_membrane_3,ABC2_membrane_5
NFNHFNFO_02611	33035.JPJF01000072_gene4369	2.13e-272	754.0	COG3225@1|root,COG3225@2|Bacteria,1TT1J@1239|Firmicutes,24BC2@186801|Clostridia,3XYR3@572511|Blautia	186801|Clostridia	N	ABC-type uncharacterized transport system	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_transp_aux
NFNHFNFO_02612	33035.JPJF01000072_gene4370	2.14e-260	727.0	2EDJE@1|root,337F9@2|Bacteria,1VHEB@1239|Firmicutes,24SR6@186801|Clostridia,3XZYW@572511|Blautia	186801|Clostridia	S	DNA topoisomerase IV subunit A K02621	-	-	-	-	-	-	-	-	-	-	-	-	DUF4340
NFNHFNFO_02613	33035.JPJF01000072_gene4371	2.17e-161	456.0	COG0596@1|root,COG0596@2|Bacteria,1TR3M@1239|Firmicutes,24DR9@186801|Clostridia,3XYQ9@572511|Blautia	186801|Clostridia	S	hydrolases or acyltransferases (alpha beta hydrolase superfamily)	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
NFNHFNFO_02614	33035.JPJF01000072_gene4372	4.43e-176	491.0	COG1192@1|root,COG1192@2|Bacteria,1TP8S@1239|Firmicutes,2488C@186801|Clostridia,3XYPE@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	soj	-	-	ko:K03496	-	-	-	-	ko00000,ko03036,ko04812	-	-	-	AAA_31
NFNHFNFO_02615	33035.JPJF01000072_gene4373	9.88e-193	538.0	COG1475@1|root,COG1475@2|Bacteria,1TQ2B@1239|Firmicutes,249VV@186801|Clostridia,3XZNQ@572511|Blautia	186801|Clostridia	K	chromosome partitioning protein	spo0J	-	-	ko:K03497	-	-	-	-	ko00000,ko03000,ko03036,ko04812	-	-	-	ParBc
NFNHFNFO_02616	33035.JPJF01000072_gene4374	1.17e-100	293.0	COG1196@1|root,COG1196@2|Bacteria,1VAV4@1239|Firmicutes,24NPU@186801|Clostridia,3XZYE@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4446
NFNHFNFO_02617	33035.JPJF01000072_gene4375	2.35e-303	827.0	COG0172@1|root,COG0172@2|Bacteria,1TP4W@1239|Firmicutes,2485M@186801|Clostridia,3XYK5@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score	serS	-	6.1.1.11	ko:K01875	ko00970,map00970	M00359,M00360	R03662,R08218	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Seryl_tRNA_N,tRNA-synt_2b
NFNHFNFO_02618	33035.JPJF01000072_gene4376	7.89e-206	569.0	28J5A@1|root,2Z916@2|Bacteria,1TSGX@1239|Firmicutes,24AZU@186801|Clostridia,3XZ0E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3881
NFNHFNFO_02619	33035.JPJF01000072_gene4377	0.0	2596.0	COG2199@1|root,COG2200@1|root,COG2202@1|root,COG5001@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,COG2202@2|Bacteria,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3XZE8@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
NFNHFNFO_02620	33035.JPJF01000072_gene4378	0.0	1011.0	COG2972@1|root,COG2972@2|Bacteria,1TT1G@1239|Firmicutes,2495G@186801|Clostridia,3Y2A3@572511|Blautia	186801|Clostridia	T	Cache domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,His_kinase,dCache_1
NFNHFNFO_02621	33035.JPJF01000072_gene4379	2.69e-153	432.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V2PT@1239|Firmicutes,24H78@186801|Clostridia,3Y1TI@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_02622	33035.JPJF01000072_gene4380	1.41e-295	808.0	COG1653@1|root,COG1653@2|Bacteria,1TT8P@1239|Firmicutes,24DVQ@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02623	33035.JPJF01000072_gene4381	9.37e-200	555.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24C7D@186801|Clostridia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_02624	33035.JPJF01000072_gene4382	4.7e-178	498.0	COG0395@1|root,COG0395@2|Bacteria,1TPDZ@1239|Firmicutes,248N3@186801|Clostridia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_02625	33035.JPJF01000072_gene4383	1e-138	394.0	COG2755@1|root,COG2755@2|Bacteria,1V49F@1239|Firmicutes,24D1K@186801|Clostridia,3Y0I8@572511|Blautia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NFNHFNFO_02626	33035.JPJF01000072_gene4384	3.94e-214	600.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24977@186801|Clostridia,3Y0HZ@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
NFNHFNFO_02627	33035.JPJF01000072_gene4385	3.45e-161	473.0	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	HD_4,HTH_3
NFNHFNFO_02628	476272.RUMHYD_03247	1.88e-47	164.0	COG2186@1|root,COG2186@2|Bacteria,1V2TU@1239|Firmicutes,24GA8@186801|Clostridia,3Y0PQ@572511|Blautia	186801|Clostridia	K	Psort location	-	-	-	ko:K05799	-	-	-	-	ko00000,ko03000	-	-	-	FCD,GntR
NFNHFNFO_02629	768706.Desor_1124	2.13e-99	310.0	COG2271@1|root,COG2271@2|Bacteria,1TPYW@1239|Firmicutes,25DRD@186801|Clostridia,2679E@186807|Peptococcaceae	186801|Clostridia	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NFNHFNFO_02630	1151292.QEW_2983	6.21e-25	94.4	COG2221@1|root,COG2221@2|Bacteria,1VI3X@1239|Firmicutes,24TQ6@186801|Clostridia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_7
NFNHFNFO_02631	33035.JPJF01000051_gene747	1.65e-178	505.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,3Y1C2@572511|Blautia	186801|Clostridia	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
NFNHFNFO_02632	865861.AZSU01000003_gene2296	1.93e-116	340.0	COG1013@1|root,COG1013@2|Bacteria,1UZ67@1239|Firmicutes,247Q7@186801|Clostridia,36DRF@31979|Clostridiaceae	186801|Clostridia	C	PFAM thiamine pyrophosphate protein domain protein TPP-binding	-	-	1.2.7.11,1.2.7.3	ko:K00175	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C
NFNHFNFO_02633	568816.Acin_0623	3.21e-77	235.0	COG1014@1|root,COG1014@2|Bacteria,1V39Q@1239|Firmicutes,4H97S@909932|Negativicutes	909932|Negativicutes	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	1.2.7.3	ko:K00177	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	POR
NFNHFNFO_02634	332101.JIBU02000056_gene2632	1.3e-293	825.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,36GU1@31979|Clostridiaceae	186801|Clostridia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
NFNHFNFO_02635	768706.Desor_1122	2.09e-166	485.0	COG0591@1|root,COG0591@2|Bacteria,1TQEZ@1239|Firmicutes,24AJN@186801|Clostridia,262IJ@186807|Peptococcaceae	186801|Clostridia	E	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
NFNHFNFO_02636	33035.JPJF01000016_gene4079	1.29e-105	318.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,3XYQ8@572511|Blautia	186801|Clostridia	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.399,1.1.1.95	ko:K00058	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R01513	RC00031	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NFNHFNFO_02637	1195236.CTER_1674	3.81e-140	426.0	COG2972@1|root,COG2972@2|Bacteria,1TQZM@1239|Firmicutes,247ZV@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
NFNHFNFO_02638	1195236.CTER_1673	4.44e-100	319.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NFNHFNFO_02639	1195236.CTER_1672	2.64e-55	177.0	COG1661@1|root,COG1661@2|Bacteria,1V67W@1239|Firmicutes,24J3Y@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF296)	-	-	-	ko:K06934	-	-	-	-	ko00000	-	-	-	DUF296
NFNHFNFO_02640	1195236.CTER_1671	5.53e-131	394.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24977@186801|Clostridia,3WJP9@541000|Ruminococcaceae	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02641	469596.HMPREF9488_00495	3.12e-292	797.0	COG2946@1|root,COG2946@2|Bacteria,1UHNT@1239|Firmicutes,3VP4X@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Replication initiation factor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3,Rep_trans
NFNHFNFO_02642	1235790.C805_01420	9.65e-22	84.7	2E3NJ@1|root,32YKN@2|Bacteria,1VIHR@1239|Firmicutes,24SDK@186801|Clostridia,25Z8P@186806|Eubacteriaceae	186801|Clostridia	S	Protein of unknown function (DUF3789)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3789
NFNHFNFO_02643	1235790.C805_01419	8.37e-42	137.0	2C9BX@1|root,32RP2@2|Bacteria,1VANR@1239|Firmicutes,24N4I@186801|Clostridia,25X23@186806|Eubacteriaceae	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02644	469596.HMPREF9488_00498	3.18e-141	399.0	28P15@1|root,2ZBXJ@2|Bacteria,1V5S6@1239|Firmicutes,3VR4B@526524|Erysipelotrichia	526524|Erysipelotrichia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02645	469596.HMPREF9488_00500	8.2e-118	337.0	COG4734@1|root,COG4734@2|Bacteria,1UX6H@1239|Firmicutes,3VPP6@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NFNHFNFO_02646	1235790.C805_01415	4.4e-122	347.0	COG4734@1|root,COG4734@2|Bacteria,1TNY7@1239|Firmicutes,249HA@186801|Clostridia,25WNI@186806|Eubacteriaceae	186801|Clostridia	S	Antirestriction protein (ArdA)	-	-	-	-	-	-	-	-	-	-	-	-	ArdA
NFNHFNFO_02647	658659.HMPREF0983_00900	4.35e-62	191.0	28I70@1|root,2Z89W@2|Bacteria,1V1TC@1239|Firmicutes,3VQEW@526524|Erysipelotrichia	526524|Erysipelotrichia	S	TcpE family	-	-	-	-	-	-	-	-	-	-	-	-	TcpE
NFNHFNFO_02648	469596.HMPREF9488_00505	1.63e-80	245.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,3VPH3@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Conjugative transposon protein TcpC	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
NFNHFNFO_02649	1504823.CCMM01000013_gene2513	3.12e-85	253.0	28PRX@1|root,2ZCDJ@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02650	1504823.CCMM01000013_gene2515	4.65e-91	267.0	28PAQ@1|root,2ZC3T@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02651	1504823.CCMM01000013_gene2516	3.8e-43	140.0	COG0582@1|root,COG0582@2|Bacteria	2|Bacteria	L	DNA integration	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NFNHFNFO_02652	469596.HMPREF9488_00513	6.34e-94	274.0	COG1595@1|root,COG1595@2|Bacteria,1TSMC@1239|Firmicutes,3VPVS@526524|Erysipelotrichia	526524|Erysipelotrichia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
NFNHFNFO_02653	469596.HMPREF9488_00514	1.41e-52	165.0	2BNIM@1|root,32H78@2|Bacteria,1UHK4@1239|Firmicutes,3VR26@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NFNHFNFO_02654	1256908.HMPREF0373_03080	1.57e-50	160.0	2BVCS@1|root,32QSU@2|Bacteria,1UHK3@1239|Firmicutes	1239|Firmicutes	S	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_16
NFNHFNFO_02655	411463.EUBVEN_00782	2.91e-86	254.0	COG1595@1|root,COG1595@2|Bacteria,1V1UU@1239|Firmicutes,24G23@186801|Clostridia,25W9K@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4_2
NFNHFNFO_02656	1235799.C818_00074	3.53e-29	104.0	2DP5Q@1|root,330MY@2|Bacteria,1VFAQ@1239|Firmicutes,24R7E@186801|Clostridia,27PN8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Cysteine-rich KTR	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_KTR
NFNHFNFO_02657	536232.CLM_0861	1.88e-75	233.0	COG0693@1|root,COG0693@2|Bacteria,1TPJK@1239|Firmicutes,24BTV@186801|Clostridia,36DI2@31979|Clostridiaceae	186801|Clostridia	S	PfpI family	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
NFNHFNFO_02658	1211817.CCAT010000062_gene3990	7.72e-92	282.0	COG2378@1|root,COG2378@2|Bacteria,1V5QT@1239|Firmicutes,24EKM@186801|Clostridia,36GXW@31979|Clostridiaceae	186801|Clostridia	K	WYL domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11,WYL
NFNHFNFO_02659	1232447.BAHW02000032_gene2471	1.4e-28	104.0	COG0582@1|root,COG0582@2|Bacteria,1VBGF@1239|Firmicutes,24NRM@186801|Clostridia	186801|Clostridia	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02660	1256908.HMPREF0373_03069	2.02e-293	805.0	COG0534@1|root,COG0534@2|Bacteria,1TPPJ@1239|Firmicutes,25AZE@186801|Clostridia,25VET@186806|Eubacteriaceae	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_02661	1256908.HMPREF0373_03068	6.34e-194	539.0	COG2207@1|root,COG2207@2|Bacteria,1TQKE@1239|Firmicutes,24A8P@186801|Clostridia,25VTA@186806|Eubacteriaceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Cass2,HTH_18
NFNHFNFO_02662	1280698.AUJS01000076_gene3401	4.81e-29	108.0	COG1595@1|root,COG1595@2|Bacteria,1V22M@1239|Firmicutes,24EDG@186801|Clostridia,27WU8@189330|Dorea	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sigma70_r4_2
NFNHFNFO_02663	537013.CLOSTMETH_02162	2.2e-216	597.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPIM@1239|Firmicutes,2480Y@186801|Clostridia	186801|Clostridia	K	transcription activator, effector binding	-	-	-	-	-	-	-	-	-	-	-	-	Cass2,HTH_18
NFNHFNFO_02664	537013.CLOSTMETH_02163	1.36e-127	363.0	COG1670@1|root,COG1670@2|Bacteria,1V5QW@1239|Firmicutes,24I6U@186801|Clostridia,3WKH2@541000|Ruminococcaceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
NFNHFNFO_02665	537013.CLOSTMETH_02164	2.05e-109	315.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia,3WH52@541000|Ruminococcaceae	186801|Clostridia	S	Methyltransferase, YaeB family	-	-	-	-	-	-	-	-	-	-	-	-	UPF0066
NFNHFNFO_02666	537013.CLOSTMETH_02165	9e-187	520.0	COG0789@1|root,COG0789@2|Bacteria,1TRYB@1239|Firmicutes,24GSY@186801|Clostridia,3WS7U@541000|Ruminococcaceae	186801|Clostridia	K	Bacterial transcription activator, effector binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Cass2,GyrI-like,MerR_1
NFNHFNFO_02667	1256908.HMPREF0373_00069	3.08e-38	128.0	COG0582@1|root,COG0582@2|Bacteria,1VBGF@1239|Firmicutes,24NRM@186801|Clostridia,25YTQ@186806|Eubacteriaceae	186801|Clostridia	L	viral genome integration into host DNA	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02668	476272.RUMHYD_01068	1.69e-162	455.0	28IFW@1|root,2Z8HG@2|Bacteria,1UNS6@1239|Firmicutes,24AB6@186801|Clostridia,3Y1FX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	CBAH
NFNHFNFO_02669	476272.RUMHYD_01069	1.8e-123	352.0	COG1309@1|root,COG1309@2|Bacteria,1V1DM@1239|Firmicutes,24QCN@186801|Clostridia,3Y0RR@572511|Blautia	186801|Clostridia	K	WHG domain	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N,WHG
NFNHFNFO_02670	500632.CLONEX_02862	4.8e-107	315.0	28IGH@1|root,2Z8HY@2|Bacteria,1TQX2@1239|Firmicutes,249TA@186801|Clostridia	186801|Clostridia	S	COG NOG08579 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	TpcC
NFNHFNFO_02671	1235790.C805_01413	2.4e-144	430.0	COG0433@1|root,COG0433@2|Bacteria,1TPVQ@1239|Firmicutes,24AAP@186801|Clostridia,25VYU@186806|Eubacteriaceae	186801|Clostridia	S	AAA-like domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10
NFNHFNFO_02672	537013.CLOSTMETH_02189	0.0	1749.0	COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,24AX1@186801|Clostridia,3WHBR@541000|Ruminococcaceae	186801|Clostridia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
NFNHFNFO_02673	33035.JPJF01000016_gene3985	1.74e-92	270.0	COG5015@1|root,COG5015@2|Bacteria,1V43Y@1239|Firmicutes,24HQB@186801|Clostridia	186801|Clostridia	K	PFAM pyridoxamine 5'-phosphate	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
NFNHFNFO_02674	33035.JPJF01000016_gene3983	0.0	1050.0	COG0119@1|root,COG0119@2|Bacteria,1TP4Y@1239|Firmicutes,2485A@186801|Clostridia,3XYGQ@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)	leuA	-	2.3.3.13	ko:K01649	ko00290,ko00620,ko01100,ko01110,ko01210,ko01230,map00290,map00620,map01100,map01110,map01210,map01230	M00432	R01213	RC00004,RC00470,RC02754	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like,HTH_18,LeuA_dimer
NFNHFNFO_02676	33035.JPJF01000016_gene3980	4.62e-171	479.0	COG3773@1|root,COG3773@2|Bacteria,1VAUD@1239|Firmicutes,25B1B@186801|Clostridia,3XZWR@572511|Blautia	186801|Clostridia	M	Cell Wall Hydrolase	-	-	3.5.1.28	ko:K01449	-	-	R04112	RC00064,RC00141	ko00000,ko01000	-	-	-	Hydrolase_2,LysM
NFNHFNFO_02677	33035.JPJF01000016_gene3979	0.0	924.0	COG0498@1|root,COG0498@2|Bacteria,1TPR0@1239|Firmicutes,248YY@186801|Clostridia,3XZ3J@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS16355	PALP,Thr_synth_N
NFNHFNFO_02678	33035.JPJF01000016_gene3978	0.0	1121.0	COG1866@1|root,COG1866@2|Bacteria,1TPXB@1239|Firmicutes,24BKF@186801|Clostridia	186801|Clostridia	H	Phosphoenolpyruvate carboxykinase (ATP)	-	-	4.1.1.49	ko:K01610	ko00010,ko00020,ko00620,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00710,map01100,map01110,map01120,map01130,map01200	M00003,M00170	R00341	RC00002,RC02741	ko00000,ko00001,ko00002,ko01000	-	-	-	PEPCK_ATP
NFNHFNFO_02679	33035.JPJF01000016_gene3977	2.26e-168	472.0	COG2206@1|root,COG2206@2|Bacteria,1V23X@1239|Firmicutes,24GQ5@186801|Clostridia,3XZI6@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HD
NFNHFNFO_02680	33035.JPJF01000016_gene3976	4.41e-247	679.0	COG2017@1|root,COG2017@2|Bacteria,1TQGJ@1239|Firmicutes,249DZ@186801|Clostridia,3XZFA@572511|Blautia	186801|Clostridia	G	Converts alpha-aldose to the beta-anomer	mro	-	5.1.3.3	ko:K01785	ko00010,ko00052,ko01100,ko01110,ko01120,ko01130,map00010,map00052,map01100,map01110,map01120,map01130	M00632	R01602,R10619	RC00563	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldose_epim
NFNHFNFO_02681	33035.JPJF01000016_gene3975	0.0	921.0	COG4262@1|root,COG4262@2|Bacteria,1UYRF@1239|Firmicutes,24AHS@186801|Clostridia	186801|Clostridia	S	Spermine/spermidine synthase domain	-	-	-	-	-	-	-	-	-	-	-	-	Spermine_synth
NFNHFNFO_02682	33035.JPJF01000016_gene3974	3.89e-281	776.0	COG2385@1|root,COG2385@2|Bacteria,1UW6J@1239|Firmicutes,24CYM@186801|Clostridia,3XYJD@572511|Blautia	186801|Clostridia	D	Stage II sporulation protein	-	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
NFNHFNFO_02683	33035.JPJF01000016_gene3973	8.55e-205	570.0	COG1295@1|root,COG1295@2|Bacteria,1U7HM@1239|Firmicutes,24A2Q@186801|Clostridia,3XZ63@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	yihY	-	-	ko:K07058	-	-	-	-	ko00000	-	-	-	Virul_fac_BrkB
NFNHFNFO_02684	33035.JPJF01000016_gene3972	3.12e-228	630.0	COG0016@1|root,COG0016@2|Bacteria,1TPFW@1239|Firmicutes,2486E@186801|Clostridia,3XYKQ@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 10.00	pheS	-	6.1.1.20	ko:K01889	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Phe_tRNA-synt_N,tRNA-synt_2d
NFNHFNFO_02685	33035.JPJF01000016_gene3971	0.0	1545.0	COG0072@1|root,COG0072@2|Bacteria,1TP98@1239|Firmicutes,248BJ@186801|Clostridia,3XYMD@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	pheT	GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464	6.1.1.20	ko:K01890	ko00970,map00970	M00359,M00360	R03660	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	B3_4,B5,FDX-ACB,tRNA-synt_2d,tRNA_bind
NFNHFNFO_02686	33035.JPJF01000016_gene3970	9.22e-147	412.0	COG0406@1|root,COG0406@2|Bacteria,1V6ES@1239|Firmicutes,24BUG@186801|Clostridia,3Y00C@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NFNHFNFO_02687	33035.JPJF01000016_gene3969	7.39e-240	660.0	COG0809@1|root,COG0809@2|Bacteria,1TPKD@1239|Firmicutes,247NT@186801|Clostridia,3XZ7B@572511|Blautia	186801|Clostridia	H	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)	queA	-	2.4.99.17	ko:K07568	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Queuosine_synth
NFNHFNFO_02688	553973.CLOHYLEM_07175	3.25e-290	802.0	COG2199@1|root,COG2199@2|Bacteria,1U3KI@1239|Firmicutes,24CEI@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
NFNHFNFO_02689	553973.CLOHYLEM_07174	0.0	1261.0	COG2199@1|root,COG5001@1|root,COG2199@2|Bacteria,COG5001@2|Bacteria,1V0FH@1239|Firmicutes,24A9M@186801|Clostridia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
NFNHFNFO_02690	658086.HMPREF0994_05656	2.36e-219	620.0	COG2188@1|root,COG2188@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K02027,ko:K03710	-	M00207	-	-	ko00000,ko00002,ko02000,ko03000	3.A.1.1	-	-	GntR
NFNHFNFO_02691	1304284.L21TH_0969	1.96e-21	99.4	COG2234@1|root,COG2234@2|Bacteria,1V4PT@1239|Firmicutes,25BCX@186801|Clostridia,36WDI@31979|Clostridiaceae	186801|Clostridia	S	Peptidase family M28	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M28
NFNHFNFO_02692	553973.CLOHYLEM_07558	2.18e-102	300.0	COG1309@1|root,COG1309@2|Bacteria,1VH8G@1239|Firmicutes,24SA7@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NFNHFNFO_02693	553973.CLOHYLEM_07557	1.34e-204	567.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,24941@186801|Clostridia,21YFG@1506553|Lachnoclostridium	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_02694	553973.CLOHYLEM_07556	5.38e-184	515.0	COG1131@1|root,COG1131@2|Bacteria,1TQHS@1239|Firmicutes,24941@186801|Clostridia,21YFG@1506553|Lachnoclostridium	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_02695	553973.CLOHYLEM_07555	3.68e-247	683.0	COG1277@1|root,COG1277@2|Bacteria,1UYSH@1239|Firmicutes	1239|Firmicutes	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
NFNHFNFO_02696	1379858.N508_00614	2.88e-15	77.8	COG1309@1|root,COG1309@2|Bacteria	2|Bacteria	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_02697	435591.BDI_1710	4.8e-58	181.0	COG5561@1|root,COG5561@2|Bacteria,4PEPI@976|Bacteroidetes,2FY87@200643|Bacteroidia	976|Bacteroidetes	S	CGGC	-	-	-	-	-	-	-	-	-	-	-	-	CGGC
NFNHFNFO_02698	33035.JPJF01000016_gene3947	3.06e-09	57.8	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_9,Response_reg
NFNHFNFO_02699	33035.JPJF01000016_gene3946	0.0	1036.0	COG2199@1|root,COG2199@2|Bacteria,COG3706@2|Bacteria,1U78Z@1239|Firmicutes,24NZ8@186801|Clostridia,3Y14E@572511|Blautia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3
NFNHFNFO_02700	33035.JPJF01000016_gene3945	2.15e-142	405.0	COG0745@1|root,COG0745@2|Bacteria,1TSNV@1239|Firmicutes,2493A@186801|Clostridia,3Y04C@572511|Blautia	186801|Clostridia	KT	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_02701	33035.JPJF01000016_gene3944	2.99e-96	289.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,24CJ8@186801|Clostridia,3XZXT@572511|Blautia	186801|Clostridia	T	His Kinase A (phospho-acceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_02703	33035.JPJF01000016_gene3943	4.74e-139	395.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,3XZQT@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_02704	33035.JPJF01000016_gene3942	0.0	1363.0	COG0577@1|root,COG0577@2|Bacteria,1TV1M@1239|Firmicutes,24E2X@186801|Clostridia,3Y0XJ@572511|Blautia	186801|Clostridia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
NFNHFNFO_02705	33035.JPJF01000016_gene3939	5.24e-278	761.0	COG0426@1|root,COG0426@2|Bacteria,1TQE9@1239|Firmicutes,249CU@186801|Clostridia,3XYHM@572511|Blautia	186801|Clostridia	C	anaerobic nitric oxide reductase flavorubredoxin	norV	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1,Flavodoxin_5,Lactamase_B,Lactamase_B_2
NFNHFNFO_02706	33035.JPJF01000016_gene3937	3.08e-96	284.0	2996G@1|root,2ZW9T@2|Bacteria,1VG83@1239|Firmicutes,24TDX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02707	33035.JPJF01000016_gene3936	2.37e-129	367.0	COG0450@1|root,COG0450@2|Bacteria,1TQU7@1239|Firmicutes,24A31@186801|Clostridia,3Y1GN@572511|Blautia	186801|Clostridia	O	C-terminal domain of 1-Cys peroxiredoxin	ahpC	-	1.11.1.15	ko:K03386	ko04214,map04214	-	-	-	ko00000,ko00001,ko01000,ko04147	-	-	-	1-cysPrx_C,AhpC-TSA
NFNHFNFO_02708	33035.JPJF01000016_gene3935	0.0	901.0	COG0492@1|root,COG3634@1|root,COG0492@2|Bacteria,COG3634@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3Y126@572511|Blautia	186801|Clostridia	C	Thioredoxin domain	trxB1	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2,Thioredoxin_3
NFNHFNFO_02709	33035.JPJF01000016_gene3934	2.83e-225	633.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3Y1FR@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GAF,GGDEF,PAS_3
NFNHFNFO_02710	33035.JPJF01000016_gene3931	3.18e-239	665.0	COG1653@1|root,COG1653@2|Bacteria,1TR6Q@1239|Firmicutes,24CVU@186801|Clostridia	186801|Clostridia	G	ABC transporter periplasmic binding protein ycjN	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_02711	33035.JPJF01000016_gene3930	0.0	1780.0	COG0642@1|root,COG0784@1|root,COG2199@1|root,COG0784@2|Bacteria,COG2199@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg,dCache_1
NFNHFNFO_02712	33035.JPJF01000016_gene3929	5.89e-125	360.0	COG5587@1|root,COG5587@2|Bacteria,1TX75@1239|Firmicutes,24CP8@186801|Clostridia	186801|Clostridia	S	Conserved hypothetical protein (DUF2461)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2461
NFNHFNFO_02713	33035.JPJF01000016_gene3928	7e-172	483.0	COG1595@1|root,COG1595@2|Bacteria,1TSCX@1239|Firmicutes,24CVD@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_02714	33035.JPJF01000016_gene3927	0.0	1787.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0642@2|Bacteria,COG0784@2|Bacteria,COG2202@2|Bacteria,1TSDF@1239|Firmicutes,250SJ@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,Response_reg,SnoaL_3
NFNHFNFO_02716	537007.BLAHAN_06456	4.81e-81	241.0	COG0103@1|root,COG0103@2|Bacteria,1V3MQ@1239|Firmicutes,24H94@186801|Clostridia,3Y045@572511|Blautia	186801|Clostridia	J	Belongs to the universal ribosomal protein uS9 family	rpsI	-	-	ko:K02996	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S9
NFNHFNFO_02717	33035.JPJF01000019_gene4265	1.18e-98	286.0	COG0102@1|root,COG0102@2|Bacteria,1V3HX@1239|Firmicutes,24HD9@186801|Clostridia,3XZVZ@572511|Blautia	186801|Clostridia	J	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly	rplM	-	-	ko:K02871	ko03010,map03010	M00178,M00179	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L13
NFNHFNFO_02718	33035.JPJF01000019_gene4262	0.0	1165.0	COG1297@1|root,COG1297@2|Bacteria,1TQJP@1239|Firmicutes,247JY@186801|Clostridia,3XYVS@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	OPT
NFNHFNFO_02719	33035.JPJF01000019_gene4261	5.21e-82	242.0	2E6A2@1|root,330XY@2|Bacteria,1VISZ@1239|Firmicutes,24QK3@186801|Clostridia,3Y0F4@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PqqD
NFNHFNFO_02720	33035.JPJF01000019_gene4260	6.17e-85	253.0	COG0607@1|root,COG0607@2|Bacteria,1U0PW@1239|Firmicutes,24RKU@186801|Clostridia,3Y0JZ@572511|Blautia	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
NFNHFNFO_02721	33035.JPJF01000019_gene4259	3.9e-201	560.0	COG0502@1|root,COG0502@2|Bacteria,1TPQ4@1239|Firmicutes,248J4@186801|Clostridia,3XYUJ@572511|Blautia	186801|Clostridia	H	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism	bioB	-	2.8.1.6	ko:K01012	ko00780,ko01100,map00780,map01100	M00123,M00573,M00577	R01078	RC00441	ko00000,ko00001,ko00002,ko01000	-	-	-	BATS,Radical_SAM
NFNHFNFO_02722	33035.JPJF01000019_gene4258	1.54e-192	536.0	COG1284@1|root,COG1284@2|Bacteria,1TRAU@1239|Firmicutes,249DE@186801|Clostridia,3XZQZ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NFNHFNFO_02723	33035.JPJF01000019_gene4257	1.48e-116	335.0	COG3822@1|root,COG3822@2|Bacteria,1V1ZU@1239|Firmicutes,24ENY@186801|Clostridia	186801|Clostridia	S	ABC-type sugar transport system, auxiliary component	-	-	-	-	-	-	-	-	-	-	-	-	Lyx_isomer
NFNHFNFO_02724	33035.JPJF01000019_gene4256	0.0	1613.0	COG3250@1|root,COG3250@2|Bacteria,1UZDI@1239|Firmicutes,24C7N@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_N
NFNHFNFO_02725	33035.JPJF01000019_gene4255	9.56e-243	666.0	COG1063@1|root,COG1063@2|Bacteria,1UI0K@1239|Firmicutes,24ATX@186801|Clostridia	186801|Clostridia	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_02726	33035.JPJF01000019_gene4254	1.32e-188	525.0	COG1082@1|root,COG1082@2|Bacteria,1VBV1@1239|Firmicutes,252TF@186801|Clostridia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NFNHFNFO_02727	33035.JPJF01000019_gene4251	2.06e-244	678.0	COG1653@1|root,COG1653@2|Bacteria,1TSHR@1239|Firmicutes,24D6W@186801|Clostridia	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02728	33035.JPJF01000019_gene4250	2.29e-227	628.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,248MY@186801|Clostridia	186801|Clostridia	E	Alcohol dehydrogenase zinc-binding domain protein	-	-	1.1.1.287	ko:K17818	ko00040,ko01100,map00040,map01100	-	R07143,R07144	RC00102	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_02729	33035.JPJF01000019_gene4249	8.45e-74	222.0	COG1869@1|root,COG1869@2|Bacteria,1VA2V@1239|Firmicutes,24MPJ@186801|Clostridia,3Y0PG@572511|Blautia	186801|Clostridia	G	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose	rbsD	-	5.4.99.62	ko:K06726	ko02010,map02010	-	R08247	RC02247	ko00000,ko00001,ko01000	-	-	-	RbsD_FucU
NFNHFNFO_02730	33035.JPJF01000019_gene4248	3.51e-184	513.0	COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,24AF7@186801|Clostridia	186801|Clostridia	G	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)	-	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
NFNHFNFO_02731	33035.JPJF01000019_gene4247	2.29e-230	635.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,3Y0AI@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NFNHFNFO_02732	33035.JPJF01000019_gene4246	1.82e-276	757.0	COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,24AE3@186801|Clostridia,3Y1MA@572511|Blautia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
NFNHFNFO_02733	33035.JPJF01000019_gene4245	5.24e-111	321.0	COG0572@1|root,COG0572@2|Bacteria,1TQ4V@1239|Firmicutes,24850@186801|Clostridia,3Y0RJ@572511|Blautia	186801|Clostridia	F	Phosphoribulokinase / Uridine kinase family	udk	-	2.7.1.48	ko:K00876	ko00240,ko00983,ko01100,map00240,map00983,map01100	-	R00513,R00516,R00517,R00962,R00964,R00967,R00968,R00970,R01548,R01549,R01880,R02091,R02096,R02097,R02327,R02332,R02371,R02372,R08232	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PRK
NFNHFNFO_02734	33035.JPJF01000019_gene4244	8.62e-114	327.0	COG0655@1|root,COG0655@2|Bacteria,1TSDE@1239|Firmicutes,24CNT@186801|Clostridia,3XZ9D@572511|Blautia	186801|Clostridia	S	COG COG0655 Multimeric flavodoxin WrbA	-	-	-	-	-	-	-	-	-	-	-	-	FMN_red
NFNHFNFO_02735	33035.JPJF01000019_gene4243	0.0	1027.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,3XZKC@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1,Amidohydro_3
NFNHFNFO_02736	33035.JPJF01000019_gene4242	3.06e-299	818.0	COG2252@1|root,COG2252@2|Bacteria,1TQC6@1239|Firmicutes,2483Q@186801|Clostridia,3XZ77@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K06901	-	-	-	-	ko00000,ko02000	2.A.1.40	-	-	Xan_ur_permease
NFNHFNFO_02737	33035.JPJF01000019_gene4241	1.4e-210	583.0	COG0583@1|root,COG0583@2|Bacteria,1TTAM@1239|Firmicutes,25C6U@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_02738	33035.JPJF01000019_gene4231	8.19e-151	429.0	COG2110@1|root,COG2110@2|Bacteria,1TQSZ@1239|Firmicutes,24935@186801|Clostridia,3XZYZ@572511|Blautia	186801|Clostridia	S	phosphatase homologous to the C-terminal domain of histone macroH2A1	-	-	-	-	-	-	-	-	-	-	-	-	Macro
NFNHFNFO_02739	33035.JPJF01000019_gene4230	7.76e-192	535.0	COG0846@1|root,COG0846@2|Bacteria,1TQB7@1239|Firmicutes,247UN@186801|Clostridia,3XZV8@572511|Blautia	186801|Clostridia	K	COG COG0846 NAD-dependent protein deacetylases, SIR2 family	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02740	33035.JPJF01000019_gene4228	0.0	1040.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF
NFNHFNFO_02741	33035.JPJF01000019_gene4227	1.69e-301	827.0	COG1215@1|root,COG1215@2|Bacteria,1TR2P@1239|Firmicutes,248SW@186801|Clostridia,3Y16E@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family group 2	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_18,Glyco_tranf_2_3,Glycos_transf_2,Polysacc_deac_1
NFNHFNFO_02742	33035.JPJF01000019_gene4226	4.06e-236	654.0	COG1413@1|root,COG1413@2|Bacteria,1VCSX@1239|Firmicutes,25K0K@186801|Clostridia,3Y1V3@572511|Blautia	186801|Clostridia	C	lyase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02743	33035.JPJF01000019_gene4225	0.0	1367.0	COG0457@1|root,COG0457@2|Bacteria,1TSH7@1239|Firmicutes,248J1@186801|Clostridia,3Y14T@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02744	33035.JPJF01000019_gene4224	0.0	894.0	COG4935@1|root,COG4935@2|Bacteria,1UI0J@1239|Firmicutes,25E97@186801|Clostridia	186801|Clostridia	O	CotH kinase protein	-	-	-	-	-	-	-	-	-	-	-	-	CotH
NFNHFNFO_02745	33035.JPJF01000019_gene4223	2.48e-139	395.0	COG1285@1|root,COG1285@2|Bacteria,1TRUW@1239|Firmicutes,248G4@186801|Clostridia,3Y0H7@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4956
NFNHFNFO_02746	33035.JPJF01000019_gene4222	3.51e-155	436.0	COG5036@1|root,COG5036@2|Bacteria,1V27Y@1239|Firmicutes,25D4R@186801|Clostridia,3Y0DX@572511|Blautia	186801|Clostridia	P	VTC domain	-	-	-	-	-	-	-	-	-	-	-	-	VTC
NFNHFNFO_02747	33035.JPJF01000019_gene4221	4.67e-176	495.0	2CABP@1|root,2Z7KZ@2|Bacteria,1U7V1@1239|Firmicutes,24C2H@186801|Clostridia,3Y1UZ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02748	33035.JPJF01000019_gene4219	1.14e-15	70.9	COG1687@1|root,COG1687@2|Bacteria,1V9YS@1239|Firmicutes,24MSG@186801|Clostridia,3Y1UU@572511|Blautia	186801|Clostridia	E	Branched-chain amino acid transport protein (AzlD)	azlD	-	-	-	-	-	-	-	-	-	-	-	AzlD
NFNHFNFO_02749	33035.JPJF01000019_gene4218	2.14e-164	461.0	COG1296@1|root,COG1296@2|Bacteria,1TP8P@1239|Firmicutes,248NN@186801|Clostridia,3Y0ZX@572511|Blautia	186801|Clostridia	E	AzlC protein	azlC	-	-	-	-	-	-	-	-	-	-	-	AzlC
NFNHFNFO_02750	720554.Clocl_1773	7.93e-40	137.0	2EAWX@1|root,334Y4@2|Bacteria,1W6D7@1239|Firmicutes,256RN@186801|Clostridia,3WQUN@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02751	748727.CLJU_c35080	3.32e-34	123.0	COG0454@1|root,COG0456@2|Bacteria,1TUAD@1239|Firmicutes,25KJY@186801|Clostridia,36KK9@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase GNAT family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7
NFNHFNFO_02752	33035.JPJF01000019_gene4217	1.23e-103	303.0	28MX3@1|root,2ZB49@2|Bacteria,1TT80@1239|Firmicutes,24HRZ@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
NFNHFNFO_02753	33035.JPJF01000019_gene4215	9.86e-119	345.0	2CZKX@1|root,32T6M@2|Bacteria,1VCXM@1239|Firmicutes,24PS9@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02754	33035.JPJF01000019_gene4214	6.13e-159	449.0	COG1131@1|root,COG1131@2|Bacteria,1V36A@1239|Firmicutes,24H15@186801|Clostridia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_02755	33035.JPJF01000019_gene4213	4.26e-108	317.0	COG0681@1|root,COG0681@2|Bacteria,1VZKQ@1239|Firmicutes,253YU@186801|Clostridia	186801|Clostridia	U	Putative zinc-finger	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
NFNHFNFO_02756	33035.JPJF01000019_gene4212	8.25e-96	281.0	COG1595@1|root,COG1595@2|Bacteria,1VIDJ@1239|Firmicutes,24SAJ@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_02757	33035.JPJF01000019_gene4211	2.98e-90	268.0	COG1396@1|root,COG1396@2|Bacteria,1TQZJ@1239|Firmicutes,25E5Y@186801|Clostridia,3Y0WQ@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_02758	33035.JPJF01000019_gene4210	2.16e-88	261.0	COG1846@1|root,COG1846@2|Bacteria,1VHM5@1239|Firmicutes,24IJZ@186801|Clostridia	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NFNHFNFO_02759	1226325.HMPREF1548_01310	1.51e-278	778.0	COG4129@1|root,COG5096@1|root,COG4129@2|Bacteria,COG5096@2|Bacteria,1UI0I@1239|Firmicutes,25E96@186801|Clostridia,36V31@31979|Clostridiaceae	186801|Clostridia	U	Fusaric acid resistance protein-like	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
NFNHFNFO_02760	457421.CBFG_00263	1.56e-56	181.0	COG0454@1|root,COG0456@2|Bacteria,1VAAI@1239|Firmicutes,24ID9@186801|Clostridia	186801|Clostridia	K	COG0454 Histone acetyltransferase HPA2 and related	-	-	-	ko:K03827	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
NFNHFNFO_02761	33035.JPJF01000019_gene4206	0.0	873.0	COG0364@1|root,COG0364@2|Bacteria,1TPYF@1239|Firmicutes,24939@186801|Clostridia	186801|Clostridia	G	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone	zwf	-	1.1.1.363,1.1.1.49	ko:K00036	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,ko05230,map00030,map00480,map01100,map01110,map01120,map01130,map01200,map05230	M00004,M00006,M00008	R00835,R02736,R10907	RC00001,RC00066	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	G6PD_C,G6PD_N
NFNHFNFO_02762	33035.JPJF01000019_gene4205	0.0	870.0	COG0362@1|root,COG0362@2|Bacteria,1TP4I@1239|Firmicutes,248YA@186801|Clostridia,3Y2CG@572511|Blautia	186801|Clostridia	G	6-phosphogluconate dehydrogenase, C-terminal domain	gnd	-	1.1.1.343,1.1.1.44	ko:K00033	ko00030,ko00480,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map00480,map01100,map01110,map01120,map01130,map01200	M00004,M00006	R01528,R10221	RC00001,RC00539	ko00000,ko00001,ko00002,ko01000	-	-	-	6PGD,NAD_binding_2
NFNHFNFO_02763	33035.JPJF01000019_gene4204	1.87e-181	511.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,24DZ9@186801|Clostridia	186801|Clostridia	G	Lactonase, 7-bladed beta-propeller	-	-	-	-	-	-	-	-	-	-	-	-	Lactonase
NFNHFNFO_02764	33035.JPJF01000019_gene4203	1.42e-135	387.0	COG0120@1|root,COG0120@2|Bacteria,1V1DB@1239|Firmicutes,248SF@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate	rpiA	-	5.3.1.6	ko:K01807	ko00030,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167,M00580	R01056	RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	Rib_5-P_isom_A
NFNHFNFO_02765	411902.CLOBOL_06110	5.34e-59	184.0	2E64N@1|root,330TH@2|Bacteria,1VF9R@1239|Firmicutes,24JHJ@186801|Clostridia,223P2@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02766	476272.RUMHYD_02319	5.25e-71	214.0	arCOG09714@1|root,316P9@2|Bacteria,1V7WP@1239|Firmicutes,24K29@186801|Clostridia,3Y230@572511|Blautia	186801|Clostridia	S	COG NOG16854 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02767	445971.ANASTE_01743	1.3e-45	153.0	COG0454@1|root,COG0456@2|Bacteria,1VBM4@1239|Firmicutes,24NCR@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_02768	1123075.AUDP01000022_gene3584	1.7e-61	191.0	COG3603@1|root,COG3603@2|Bacteria,1V9Y8@1239|Firmicutes,24JKN@186801|Clostridia,3WK32@541000|Ruminococcaceae	186801|Clostridia	S	ACT domain	-	-	-	ko:K09707	-	-	-	-	ko00000	-	-	-	ACT_7
NFNHFNFO_02769	1321372.AQQB01000003_gene1481	6.8e-97	285.0	COG0645@1|root,COG0645@2|Bacteria,1TSSD@1239|Firmicutes,4IJ7S@91061|Bacilli,1WTVK@1307|Streptococcus suis	91061|Bacilli	S	Chloramphenicol phosphotransferase-like protein	-	-	-	-	-	-	-	-	-	-	-	-	AAA_18
NFNHFNFO_02770	411468.CLOSCI_02790	7.3e-74	223.0	COG3708@1|root,COG3708@2|Bacteria,1V51M@1239|Firmicutes,24IWT@186801|Clostridia,2205B@1506553|Lachnoclostridium	186801|Clostridia	K	Protein of unknown function (DUF3788)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3788
NFNHFNFO_02771	742740.HMPREF9474_01180	8.45e-118	342.0	COG0596@1|root,COG0596@2|Bacteria,1TSPF@1239|Firmicutes,24AD1@186801|Clostridia,222JG@1506553|Lachnoclostridium	186801|Clostridia	S	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Abhydrolase_6
NFNHFNFO_02774	397290.C810_00077	1.12e-139	413.0	COG1961@1|root,COG1961@2|Bacteria,1TPUG@1239|Firmicutes,25B03@186801|Clostridia,27J4Z@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Resolvase, N terminal domain	-	-	-	ko:K06400	-	-	-	-	ko00000	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NFNHFNFO_02775	1235798.C817_01021	7.35e-30	106.0	2E3WS@1|root,32YTY@2|Bacteria,1VH43@1239|Firmicutes,24T8U@186801|Clostridia,27X6E@189330|Dorea	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02776	696281.Desru_2101	8.94e-224	627.0	2DBKS@1|root,2Z9UX@2|Bacteria,1UYSQ@1239|Firmicutes,24QEK@186801|Clostridia,266GR@186807|Peptococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02777	1408437.JNJN01000042_gene777	1.45e-68	211.0	COG2265@1|root,COG2826@1|root,COG2265@2|Bacteria,COG2826@2|Bacteria,1TQ0G@1239|Firmicutes,248WB@186801|Clostridia,25V8R@186806|Eubacteriaceae	186801|Clostridia	L	COG COG2826 Transposase and inactivated derivatives, IS30 family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_38
NFNHFNFO_02778	97139.C824_05991	4.11e-198	553.0	COG3943@1|root,COG3943@2|Bacteria,1TPH4@1239|Firmicutes,248NI@186801|Clostridia,36ERN@31979|Clostridiaceae	186801|Clostridia	S	Virulence protein RhuM family	-	-	-	-	-	-	-	-	-	-	-	-	Virulence_RhuM
NFNHFNFO_02779	574375.BAGA_15745	1.41e-106	314.0	2E47H@1|root,32Z3D@2|Bacteria,1VWJ7@1239|Firmicutes,4HZSQ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02780	574375.BAGA_15745	1.42e-19	85.1	2E47H@1|root,32Z3D@2|Bacteria,1VWJ7@1239|Firmicutes,4HZSQ@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02781	33035.JPJF01000068_gene4514	5.09e-309	848.0	COG2265@1|root,COG2265@2|Bacteria,1TP4H@1239|Firmicutes,248B4@186801|Clostridia,3XZ3E@572511|Blautia	186801|Clostridia	J	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family	rumA	-	2.1.1.190	ko:K03215	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TRAM,tRNA_U5-meth_tr
NFNHFNFO_02782	33035.JPJF01000068_gene4513	5.45e-231	635.0	COG3481@1|root,COG3481@2|Bacteria,1TPIU@1239|Firmicutes,248SS@186801|Clostridia,3XZA2@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yhaM	-	-	ko:K03698	-	-	-	-	ko00000,ko01000,ko03019	-	-	-	HD,tRNA_anti-codon
NFNHFNFO_02783	33035.JPJF01000068_gene4512	3.25e-280	771.0	COG0265@1|root,COG0265@2|Bacteria,1TTAZ@1239|Firmicutes,24BWH@186801|Clostridia,3XZG2@572511|Blautia	186801|Clostridia	O	COG COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
NFNHFNFO_02784	33035.JPJF01000068_gene4511	0.0	1392.0	COG1193@1|root,COG1193@2|Bacteria,1TP5W@1239|Firmicutes,248YK@186801|Clostridia,3XYKH@572511|Blautia	186801|Clostridia	L	Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity	mutS2	-	-	ko:K07456	ko03430,map03430	-	-	-	ko00000,ko00001,ko03400	-	-	-	MutS_V,Smr
NFNHFNFO_02785	33035.JPJF01000068_gene4510	8.73e-171	476.0	COG0745@1|root,COG0745@2|Bacteria,1TPZ0@1239|Firmicutes,249IC@186801|Clostridia,3XZ5B@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_02786	33035.JPJF01000068_gene4509	0.0	881.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XZ8I@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NFNHFNFO_02787	33035.JPJF01000068_gene4508	7.6e-118	337.0	COG0219@1|root,COG0219@2|Bacteria,1V3GW@1239|Firmicutes,24HVV@186801|Clostridia,3XYZI@572511|Blautia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. TrmL subfamily	trmL	-	2.1.1.207	ko:K03216	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	SpoU_methylase
NFNHFNFO_02788	33035.JPJF01000068_gene4507	5.85e-228	629.0	COG0309@1|root,COG0309@2|Bacteria,1TQP4@1239|Firmicutes,24963@186801|Clostridia,3XZIN@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	hypE	-	-	ko:K04655	-	-	-	-	ko00000	-	-	-	AIRS,AIRS_C
NFNHFNFO_02790	33035.JPJF01000068_gene4505	1.18e-140	401.0	COG2176@1|root,COG2176@2|Bacteria,1V3E4@1239|Firmicutes,249X5@186801|Clostridia,3XZPP@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	2.7.7.7	ko:K03763	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	RNase_T
NFNHFNFO_02791	33035.JPJF01000068_gene4504	1.1e-148	419.0	COG0177@1|root,COG0177@2|Bacteria,1TRAK@1239|Firmicutes,24899@186801|Clostridia,3XZHD@572511|Blautia	186801|Clostridia	L	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate	nth	-	4.2.99.18	ko:K10773	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD
NFNHFNFO_02792	33035.JPJF01000068_gene4503	0.0	1055.0	COG1032@1|root,COG1032@2|Bacteria,1TPGT@1239|Firmicutes,247JS@186801|Clostridia,3XZA6@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.21.98.3	ko:K04034	ko00860,ko01100,ko01110,map00860,map01100,map01110	-	R06268,R06269,R06270	RC00741,RC01491,RC01492	ko00000,ko00001,ko01000	-	-	-	B12-binding,DUF4080,Radical_SAM
NFNHFNFO_02794	33035.JPJF01000068_gene4501	0.0	1222.0	COG0370@1|root,COG0370@2|Bacteria,1TP7E@1239|Firmicutes,24885@186801|Clostridia,3Y14U@572511|Blautia	186801|Clostridia	P	Signal recognition particle receptor beta subunit	-	-	-	ko:K04759	-	-	-	-	ko00000,ko02000	9.A.8.1	-	-	FeoB_C,FeoB_N,Gate
NFNHFNFO_02795	33035.JPJF01000068_gene4500	4.77e-42	138.0	COG1918@1|root,COG1918@2|Bacteria,1VKST@1239|Firmicutes,24UDC@186801|Clostridia	186801|Clostridia	P	FeoA domain	-	-	-	-	-	-	-	-	-	-	-	-	FeoA
NFNHFNFO_02796	33035.JPJF01000068_gene4499	1.34e-268	740.0	COG0475@1|root,COG0475@2|Bacteria,1TS32@1239|Firmicutes,247XW@186801|Clostridia,3XZ6K@572511|Blautia	186801|Clostridia	P	Sodium/hydrogen exchanger family	napA	-	-	-	-	-	-	-	-	-	-	-	Na_H_Exchanger
NFNHFNFO_02797	33035.JPJF01000068_gene4498	0.0	1424.0	COG1328@1|root,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3XYTU@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,NRDD
NFNHFNFO_02798	33035.JPJF01000068_gene4497	3.05e-299	819.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3XZ7G@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_02799	33035.JPJF01000068_gene4496	9.47e-197	548.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3XZFN@572511|Blautia	186801|Clostridia	E	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
NFNHFNFO_02800	33035.JPJF01000068_gene4495	2.8e-229	631.0	COG2221@1|root,COG2221@2|Bacteria,1UI1A@1239|Firmicutes,25EAA@186801|Clostridia,3Y28E@572511|Blautia	186801|Clostridia	C	Nitrite and sulphite reductase 4Fe-4S domain	dsvA	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C,Fer4,Fer4_10,NIR_SIR,NIR_SIR_ferr
NFNHFNFO_02801	33035.JPJF01000068_gene4494	0.0	1011.0	COG0446@1|root,COG0607@1|root,COG0446@2|Bacteria,COG0607@2|Bacteria,1TPWW@1239|Firmicutes,2484C@186801|Clostridia,3XZD7@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,NIR_SIR,NIR_SIR_ferr,Pyr_redox_2,Pyr_redox_dim,Rhodanese
NFNHFNFO_02802	33035.JPJF01000068_gene4493	9.04e-205	568.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,24970@186801|Clostridia,3XZ9Y@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_02803	500632.CLONEX_03862	1.41e-33	115.0	COG1773@1|root,COG1773@2|Bacteria,1VEQC@1239|Firmicutes,24QUV@186801|Clostridia	186801|Clostridia	C	rubredoxin	rd	-	-	-	-	-	-	-	-	-	-	-	Rubredoxin
NFNHFNFO_02804	33035.JPJF01000068_gene4491	4.97e-102	296.0	2BRC2@1|root,32KAP@2|Bacteria,1V6Y3@1239|Firmicutes,24KI1@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02805	33035.JPJF01000068_gene4490	0.0	976.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia	186801|Clostridia	C	Na H antiporter	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
NFNHFNFO_02806	33035.JPJF01000068_gene4489	0.0	972.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia,3Y1C9@572511|Blautia	186801|Clostridia	E	Aromatic amino acid lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
NFNHFNFO_02807	33035.JPJF01000068_gene4488	0.0	1867.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1TR6V@1239|Firmicutes,24AA2@186801|Clostridia,3Y13S@572511|Blautia	186801|Clostridia	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
NFNHFNFO_02808	33035.JPJF01000068_gene4487	3.11e-140	398.0	COG0664@1|root,COG0664@2|Bacteria,1VCZE@1239|Firmicutes,24PP3@186801|Clostridia	186801|Clostridia	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
NFNHFNFO_02809	742733.HMPREF9469_02275	1.18e-22	93.6	2DSCR@1|root,33FK0@2|Bacteria,1VKCD@1239|Firmicutes,24QWS@186801|Clostridia,22085@1506553|Lachnoclostridium	186801|Clostridia	S	Domain of unknown function (DUF3783)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3783
NFNHFNFO_02810	33035.JPJF01000068_gene4484	0.0	1176.0	COG3533@1|root,COG3533@2|Bacteria,1TRV9@1239|Firmicutes,24CKP@186801|Clostridia	186801|Clostridia	G	Beta-L-arabinofuranosidase, GH127	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_127
NFNHFNFO_02811	33035.JPJF01000068_gene4483	5.89e-180	502.0	COG0395@1|root,COG0395@2|Bacteria,1V6WK@1239|Firmicutes,24MD8@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system, permease component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_02812	33035.JPJF01000068_gene4482	2.04e-176	494.0	COG1175@1|root,COG1175@2|Bacteria,1V05I@1239|Firmicutes,24D4P@186801|Clostridia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_02813	33035.JPJF01000068_gene4481	1.63e-297	813.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,248X0@186801|Clostridia,3Y14V@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02814	33035.JPJF01000068_gene4480	9.16e-209	577.0	COG2207@1|root,COG2207@2|Bacteria,1UUVG@1239|Firmicutes,24SJE@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NFNHFNFO_02815	33035.JPJF01000068_gene4478	3.75e-193	537.0	COG0191@1|root,COG0191@2|Bacteria,1TRS4@1239|Firmicutes,24CD4@186801|Clostridia,3Y1PV@572511|Blautia	186801|Clostridia	G	Fructose-bisphosphate aldolase class-II	iolJ	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
NFNHFNFO_02816	33035.JPJF01000146_gene2134	8.69e-253	699.0	COG2223@1|root,COG2223@2|Bacteria,1TPR9@1239|Firmicutes,2483N@186801|Clostridia,3Y0Z3@572511|Blautia	186801|Clostridia	P	Major Facilitator Superfamily	-	-	-	ko:K08177	-	-	-	-	ko00000,ko02000	2.A.1.11	-	-	MFS_1
NFNHFNFO_02817	33035.JPJF01000146_gene2135	1.79e-168	472.0	COG1349@1|root,COG1349@2|Bacteria,1TTGR@1239|Firmicutes,25C4C@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	iolR	-	-	ko:K06608	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
NFNHFNFO_02818	1232447.BAHW02000038_gene2607	7.32e-216	595.0	COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,24AF7@186801|Clostridia	186801|Clostridia	G	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)	iolE	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
NFNHFNFO_02819	33035.JPJF01000088_gene6	3.06e-238	655.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,24B6F@186801|Clostridia	186801|Clostridia	E	Oxidoreductase NAD-binding domain protein	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_02820	33035.JPJF01000088_gene5	1.43e-238	657.0	COG1609@1|root,COG1609@2|Bacteria,1UI1I@1239|Firmicutes,25EAN@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_4
NFNHFNFO_02821	33035.JPJF01000141_gene2442	8.18e-62	200.0	28M3R@1|root,2ZAHU@2|Bacteria,1TR3Y@1239|Firmicutes,249MC@186801|Clostridia,3XZ6X@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02822	33035.JPJF01000141_gene2442	2.75e-33	123.0	28M3R@1|root,2ZAHU@2|Bacteria,1TR3Y@1239|Firmicutes,249MC@186801|Clostridia,3XZ6X@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02823	33035.JPJF01000088_gene3	1.99e-66	205.0	COG1846@1|root,COG1846@2|Bacteria,1VFY9@1239|Firmicutes,25CPN@186801|Clostridia	186801|Clostridia	K	MarR family	-	-	-	-	-	-	-	-	-	-	-	-	MarR_2
NFNHFNFO_02824	33035.JPJF01000088_gene2	7.48e-163	458.0	COG0730@1|root,COG0730@2|Bacteria,1TRFG@1239|Firmicutes,24AEX@186801|Clostridia,3XYTW@572511|Blautia	186801|Clostridia	S	Sulfite exporter TauE/SafE	-	-	-	ko:K07090	-	-	-	-	ko00000	-	-	-	TauE
NFNHFNFO_02825	1232447.BAHW02000038_gene2607	4.23e-213	588.0	COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,24AF7@186801|Clostridia	186801|Clostridia	G	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)	iolE	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
NFNHFNFO_02826	33035.JPJF01000134_gene4530	0.0	952.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UUVK@1239|Firmicutes,25KDA@186801|Clostridia,3Y1S9@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
NFNHFNFO_02827	33035.JPJF01000134_gene4529	0.0	1028.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NFNHFNFO_02828	33035.JPJF01000152_gene1832	7.92e-247	677.0	COG0673@1|root,COG0673@2|Bacteria,1TP83@1239|Firmicutes,248XQ@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_02829	33035.JPJF01000152_gene1831	8.11e-138	390.0	COG1102@1|root,COG1102@2|Bacteria,1V286@1239|Firmicutes,24KX2@186801|Clostridia	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NFNHFNFO_02830	33035.JPJF01000152_gene1830	0.0	892.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,3XZU5@572511|Blautia	186801|Clostridia	G	COG COG2211 Na melibiose symporter and related transporters	gph	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_02831	33035.JPJF01000152_gene1829	1.8e-189	530.0	COG1879@1|root,COG1879@2|Bacteria,1UZ0C@1239|Firmicutes,249QH@186801|Clostridia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NFNHFNFO_02832	33035.JPJF01000064_gene3842	1.63e-259	713.0	COG1454@1|root,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3Y04D@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	gbsB	-	-	-	-	-	-	-	-	-	-	-	Fe-ADH
NFNHFNFO_02833	33035.JPJF01000064_gene3841	1.58e-200	553.0	COG3718@1|root,COG3718@2|Bacteria,1TR6M@1239|Firmicutes,2491W@186801|Clostridia	186801|Clostridia	G	Myo-inositol catabolism protein IolB	iolB	-	5.3.1.30	ko:K03337	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08503	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
NFNHFNFO_02834	33035.JPJF01000064_gene3840	0.0	1271.0	COG3962@1|root,COG3962@2|Bacteria,1UI18@1239|Firmicutes,25EA8@186801|Clostridia	186801|Clostridia	E	Involved in the cleavage of the C1-C2 bond of 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (THcHDO) to yield 5-deoxy- glucuronate (5DG)	iolD	-	3.7.1.22	ko:K03336	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R08603	RC02331	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NFNHFNFO_02835	33035.JPJF01000064_gene3839	3.65e-250	686.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia	186801|Clostridia	G	Kinase, PfkB family	iolC	-	2.7.1.4,2.7.1.92	ko:K00847,ko:K03338	ko00051,ko00500,ko00520,ko00562,ko01100,ko01120,map00051,map00500,map00520,map00562,map01100,map01120	-	R00760,R00867,R03920,R05661	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NFNHFNFO_02836	1449050.JNLE01000003_gene3786	0.0	1041.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia,36GHW@31979|Clostridiaceae	186801|Clostridia	G	family 2 sugar binding	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFNHFNFO_02837	272626.lin0506	8.97e-16	85.1	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,4HBN1@91061|Bacilli,26KFM@186820|Listeriaceae	91061|Bacilli	C	Glucose dehydrogenase C-terminus	gatD	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_02838	1382356.JQMP01000001_gene944	1.4e-14	82.0	COG0673@1|root,COG0673@2|Bacteria,2G9C5@200795|Chloroflexi,27ZAV@189775|Thermomicrobia	189775|Thermomicrobia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_02839	1307436.PBF_16459	4.71e-60	199.0	COG0395@1|root,COG0395@2|Bacteria,1TQG0@1239|Firmicutes,4HD6Q@91061|Bacilli,1ZAVF@1386|Bacillus	91061|Bacilli	P	PFAM binding-protein-dependent transport systems inner membrane component	araQ5	-	-	ko:K02026,ko:K10190,ko:K10242	ko02010,map02010	M00199,M00206,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.23,3.A.1.1.4	-	-	BPD_transp_1
NFNHFNFO_02840	1238184.CM001792_gene3436	1.66e-61	204.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,4I3HM@91061|Bacilli,23MJ6@182709|Oceanobacillus	91061|Bacilli	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_02841	1499968.TCA2_2585	2e-12	77.4	COG1653@1|root,COG1653@2|Bacteria,1UNFN@1239|Firmicutes,4HCSA@91061|Bacilli,274JX@186822|Paenibacillaceae	91061|Bacilli	G	ABC-type sugar transport system, periplasmic component	srrA1	-	-	ko:K02027,ko:K17244	ko02010,map02010	M00207,M00601	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.40	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02842	1195236.CTER_1276	1.13e-61	207.0	COG1609@1|root,COG1609@2|Bacteria,1UXXV@1239|Firmicutes,24A5P@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_02843	33035.JPJF01000064_gene3838	4.43e-229	633.0	COG1879@1|root,COG1879@2|Bacteria,1TX1B@1239|Firmicutes,25EA7@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_4
NFNHFNFO_02844	33035.JPJF01000064_gene3837	1.75e-301	828.0	COG2508@1|root,COG2508@2|Bacteria	2|Bacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NFNHFNFO_02845	33035.JPJF01000064_gene3836	5.79e-122	350.0	COG0523@1|root,COG0523@2|Bacteria,1V755@1239|Firmicutes,24JV0@186801|Clostridia	1239|Firmicutes	S	CobW/HypB/UreG, nucleotide-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	cobW
NFNHFNFO_02847	33035.JPJF01000064_gene3834	6.85e-254	699.0	COG0477@1|root,COG2814@2|Bacteria,1V0CF@1239|Firmicutes,24BRB@186801|Clostridia	186801|Clostridia	EGP	Transporter, major facilitator family protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NFNHFNFO_02848	33035.JPJF01000064_gene3833	5.19e-254	695.0	COG0407@1|root,COG0407@2|Bacteria,1V9U0@1239|Firmicutes,24MDE@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_02849	33035.JPJF01000064_gene3831	3.03e-180	501.0	COG0726@1|root,COG0726@2|Bacteria,1UZGG@1239|Firmicutes,249C9@186801|Clostridia,3Y04M@572511|Blautia	186801|Clostridia	G	Polysaccharide deacetylase	pdaB	-	-	-	-	-	-	-	-	-	-	-	Polysacc_deac_1
NFNHFNFO_02850	33035.JPJF01000064_gene3829	9.29e-102	302.0	2A88Y@1|root,30XA4@2|Bacteria,1V3M4@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2812
NFNHFNFO_02851	33035.JPJF01000064_gene3828	5.51e-66	202.0	COG1695@1|root,COG1695@2|Bacteria,1VESB@1239|Firmicutes,25CVC@186801|Clostridia,3Y1WQ@572511|Blautia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
NFNHFNFO_02852	33035.JPJF01000064_gene3827	2.74e-284	777.0	COG1478@1|root,COG1478@2|Bacteria,1TSTY@1239|Firmicutes,249IH@186801|Clostridia,3Y1FJ@572511|Blautia	186801|Clostridia	S	F420-0:Gamma-glutamyl ligase	-	-	-	-	-	-	-	-	-	-	-	-	F420_ligase
NFNHFNFO_02853	33035.JPJF01000064_gene3826	6.9e-27	98.2	2EIM1@1|root,33CCB@2|Bacteria,1VM79@1239|Firmicutes,24UNI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02854	1123075.AUDP01000004_gene787	5.82e-142	412.0	COG3344@1|root,COG3344@2|Bacteria,1UZGS@1239|Firmicutes,247Z6@186801|Clostridia,3WIXG@541000|Ruminococcaceae	186801|Clostridia	L	Reverse transcriptase (RNA-dependent DNA polymerase)	-	-	-	-	-	-	-	-	-	-	-	-	RVT_1
NFNHFNFO_02862	33035.JPJF01000040_gene5172	2.21e-114	327.0	COG0622@1|root,COG0622@2|Bacteria,1VA0U@1239|Firmicutes,24MMK@186801|Clostridia,3Y05G@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfcE1	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NFNHFNFO_02863	33035.JPJF01000040_gene5173	4.91e-137	388.0	COG0127@1|root,COG0127@2|Bacteria,1V6RN@1239|Firmicutes,249GK@186801|Clostridia,3XZMM@572511|Blautia	186801|Clostridia	F	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions	rdgB	-	3.6.1.66	ko:K02428	ko00230,map00230	-	R00426,R00720,R01855,R02100,R02720,R03531	RC00002	ko00000,ko00001,ko01000	-	-	-	Ham1p_like
NFNHFNFO_02864	33035.JPJF01000040_gene5174	4.44e-273	747.0	COG0116@1|root,COG0116@2|Bacteria,1TP0X@1239|Firmicutes,248MA@186801|Clostridia,3XYQ3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ypsC	-	-	ko:K07444	-	-	-	-	ko00000,ko01000	-	-	-	THUMP,UPF0020
NFNHFNFO_02865	33035.JPJF01000040_gene5175	1.56e-126	360.0	COG0622@1|root,COG0622@2|Bacteria,1V1X1@1239|Firmicutes,24GA4@186801|Clostridia,3XZ4B@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfcE	-	-	ko:K07095	-	-	-	-	ko00000	-	-	-	Metallophos_2
NFNHFNFO_02866	33035.JPJF01000040_gene5176	1.69e-62	192.0	COG0607@1|root,COG0607@2|Bacteria,1VGXK@1239|Firmicutes,24R46@186801|Clostridia,3Y0GN@572511|Blautia	186801|Clostridia	P	Rhodanese Homology Domain	-	-	-	-	-	-	-	-	-	-	-	-	Rhodanese
NFNHFNFO_02868	33035.JPJF01000040_gene5177	2.48e-135	384.0	COG0279@1|root,COG0279@2|Bacteria,1V5W5@1239|Firmicutes,24INX@186801|Clostridia,3Y1PC@572511|Blautia	186801|Clostridia	G	SIS domain	gmhA	-	5.3.1.28	ko:K03271	ko00540,ko01100,map00540,map01100	M00064	R05645,R09768,R09769	RC00434	ko00000,ko00001,ko00002,ko01000,ko01005	-	-	-	Hydrolase_3,SIS_2
NFNHFNFO_02869	33035.JPJF01000040_gene5178	1.77e-235	648.0	COG1940@1|root,COG1940@2|Bacteria,1TRGJ@1239|Firmicutes,248TJ@186801|Clostridia,3Y148@572511|Blautia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
NFNHFNFO_02870	33035.JPJF01000040_gene5179	0.0	1562.0	COG0383@1|root,COG0383@2|Bacteria,1TQEH@1239|Firmicutes,24DH1@186801|Clostridia	186801|Clostridia	G	Alpha mannosidase, middle domain	-	-	3.2.1.24	ko:K01191	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04131	-	GH38	-	Alpha-mann_mid,Glyco_hydro_38,Glyco_hydro_38C
NFNHFNFO_02871	33035.JPJF01000040_gene5180	2.56e-184	514.0	COG0395@1|root,COG0395@2|Bacteria,1TRGH@1239|Firmicutes,24C7R@186801|Clostridia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_02872	33035.JPJF01000040_gene5181	1.52e-174	489.0	COG1175@1|root,COG1175@2|Bacteria,1TSRA@1239|Firmicutes,24E4R@186801|Clostridia	186801|Clostridia	P	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17238	ko02010,map02010	M00599	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.38	-	-	BPD_transp_1
NFNHFNFO_02873	33035.JPJF01000040_gene5182	0.0	888.0	COG1653@1|root,COG1653@2|Bacteria,1U0GS@1239|Firmicutes,24DMA@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02874	33035.JPJF01000040_gene5183	2.64e-269	740.0	COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,24AE3@186801|Clostridia,3Y1MA@572511|Blautia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	ROK
NFNHFNFO_02875	1121115.AXVN01000010_gene2786	3.05e-186	520.0	COG0395@1|root,COG0395@2|Bacteria,1TP1G@1239|Firmicutes,247T2@186801|Clostridia,3Y1FV@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_02876	1121115.AXVN01000010_gene2785	1.67e-197	549.0	COG4209@1|root,COG4209@2|Bacteria,1TQFY@1239|Firmicutes,24923@186801|Clostridia,3Y19D@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NFNHFNFO_02877	1121115.AXVN01000010_gene2784	6.48e-298	819.0	COG1653@1|root,COG1653@2|Bacteria,1TPWV@1239|Firmicutes,25NJ2@186801|Clostridia,3Y1EP@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3502
NFNHFNFO_02878	1121115.AXVN01000010_gene2783	4.8e-245	693.0	COG2972@1|root,COG2972@2|Bacteria,1U6WN@1239|Firmicutes,257VB@186801|Clostridia,3Y13A@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NFNHFNFO_02879	1121115.AXVN01000010_gene2782	6.06e-68	222.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UCUQ@1239|Firmicutes,24FD5@186801|Clostridia,3Y1DI@572511|Blautia	186801|Clostridia	KT	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_02880	457412.RSAG_01426	1.48e-154	452.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UCUQ@1239|Firmicutes,24FD5@186801|Clostridia,3WPDP@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_02881	1235792.C808_02344	4.73e-208	588.0	COG5520@1|root,COG5520@2|Bacteria,1TS99@1239|Firmicutes,249YD@186801|Clostridia,27JQQ@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolase family 30 TIM-barrel domain	-	-	3.2.1.45	ko:K01201	ko00511,ko00600,ko01100,ko04142,map00511,map00600,map01100,map04142	-	R01498	RC00059,RC00451	ko00000,ko00001,ko01000	-	GH30	-	F5_F8_type_C,Glyco_hydro_30,Glyco_hydro_30C
NFNHFNFO_02882	357809.Cphy_3405	3.44e-108	319.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UVAH@1239|Firmicutes,25KFC@186801|Clostridia,22333@1506553|Lachnoclostridium	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_02883	357809.Cphy_3406	7e-230	656.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,222RH@1506553|Lachnoclostridium	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NFNHFNFO_02884	658086.HMPREF0994_02803	4.91e-166	468.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,27N53@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_02885	357809.Cphy_3408	4.94e-174	489.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,22060@1506553|Lachnoclostridium	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_02886	658086.HMPREF0994_02801	2.8e-234	654.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24977@186801|Clostridia,27TZW@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
NFNHFNFO_02887	33035.JPJF01000040_gene5184	3.74e-63	198.0	2E4RH@1|root,32ZK1@2|Bacteria,1VEUS@1239|Firmicutes,24QIW@186801|Clostridia,3Y0M1@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NFNHFNFO_02888	33035.JPJF01000040_gene5185	2.96e-106	307.0	COG2426@1|root,COG2426@2|Bacteria,1V3UW@1239|Firmicutes,24HSW@186801|Clostridia,3XZYM@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Sm_multidrug_ex
NFNHFNFO_02889	33035.JPJF01000040_gene5186	6.61e-277	758.0	COG0436@1|root,COG0436@2|Bacteria,1TP36@1239|Firmicutes,248ZV@186801|Clostridia,3XZCR@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	yhdR	-	2.6.1.1	ko:K11358	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NFNHFNFO_02890	33035.JPJF01000040_gene5187	0.0	1080.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XZJG@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFNHFNFO_02891	33035.JPJF01000040_gene5188	0.0	1098.0	COG1404@1|root,COG1404@2|Bacteria,1TQK9@1239|Firmicutes,25B1U@186801|Clostridia,3XYR2@572511|Blautia	186801|Clostridia	O	COG COG1404 Subtilisin-like serine proteases	cspBA	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S8
NFNHFNFO_02892	33035.JPJF01000040_gene5189	3.52e-178	497.0	COG2116@1|root,COG2116@2|Bacteria,1TRTT@1239|Firmicutes,24BU5@186801|Clostridia,3XZWD@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	fnt	-	-	ko:K02598	-	-	-	-	ko00000,ko02000	1.A.16.3	-	-	Form_Nir_trans
NFNHFNFO_02893	457412.RSAG_03390	0.0	1035.0	COG2759@1|root,COG2759@2|Bacteria,1TP6N@1239|Firmicutes,247P5@186801|Clostridia,3WHBU@541000|Ruminococcaceae	186801|Clostridia	H	Belongs to the formate--tetrahydrofolate ligase family	fhs	-	6.3.4.3	ko:K01938	ko00670,ko00720,ko01100,ko01120,ko01200,map00670,map00720,map01100,map01120,map01200	M00140,M00377	R00943	RC00026,RC00111	ko00000,ko00001,ko00002,ko01000	-	-	-	FTHFS
NFNHFNFO_02894	33035.JPJF01000157_gene3600	1.96e-227	627.0	COG0524@1|root,COG0524@2|Bacteria,1TPGM@1239|Firmicutes,247M1@186801|Clostridia,3XYNT@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	2.7.1.4	ko:K00847	ko00051,ko00500,ko00520,ko01100,map00051,map00500,map00520,map01100	-	R00760,R00867,R03920	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NFNHFNFO_02895	33035.JPJF01000144_gene2339	0.0	895.0	COG1020@1|root,COG1020@2|Bacteria,1TPTH@1239|Firmicutes,2490U@186801|Clostridia	186801|Clostridia	Q	Belongs to the ATP-dependent AMP-binding enzyme family	dltA	-	6.1.1.13	ko:K03367	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	AMP-binding,AMP-binding_C
NFNHFNFO_02896	33035.JPJF01000144_gene2338	2.02e-268	736.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia	186801|Clostridia	M	Membrane protein involved in D-alanine export	dltB	-	-	ko:K03739,ko:K19294	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	MBOAT
NFNHFNFO_02897	33035.JPJF01000144_gene2337	8.51e-41	135.0	COG0236@1|root,COG0236@2|Bacteria	2|Bacteria	IQ	Carrier of the growing fatty acid chain in fatty acid biosynthesis	dltC	GO:0000270,GO:0003674,GO:0005215,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0006810,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0022857,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0051179,GO:0051234,GO:0055085,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576	6.1.1.13	ko:K02078,ko:K14188	ko00473,ko01503,ko02020,ko05150,map00473,map01503,map02020,map05150	M00725	R02718	RC00037,RC00094	ko00000,ko00001,ko00002,ko01000,ko01504	-	-	-	PP-binding
NFNHFNFO_02898	33035.JPJF01000144_gene2336	4.62e-255	702.0	COG3966@1|root,COG3966@2|Bacteria,1TSZU@1239|Firmicutes,24GMC@186801|Clostridia	186801|Clostridia	M	D-alanyl-lipoteichoic acid biosynthesis protein DltD	dltD	-	-	ko:K03740	ko01503,ko02020,ko05150,map01503,map02020,map05150	M00725	-	-	ko00000,ko00001,ko00002,ko01504	-	-	-	DltD
NFNHFNFO_02899	33035.JPJF01000144_gene2335	1.38e-162	455.0	COG0745@1|root,COG0745@2|Bacteria,1UDAQ@1239|Firmicutes,249RQ@186801|Clostridia,3XYRX@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	kdpE	-	-	ko:K07667	ko02020,ko02024,map02020,map02024	M00454	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_02900	33035.JPJF01000061_gene3656	0.0	1006.0	COG0642@1|root,COG2205@2|Bacteria,1TQHB@1239|Firmicutes,247S4@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07646	ko02020,map02020	M00454	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	DUF4118,HATPase_c,HisKA,KdpD
NFNHFNFO_02901	33035.JPJF01000061_gene3657	3.56e-152	427.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,3XZJS@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score 8.87	ktrA	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NFNHFNFO_02902	33035.JPJF01000061_gene3658	8.33e-295	808.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,3XZ2Q@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NFNHFNFO_02903	33035.JPJF01000061_gene3659	7.71e-243	671.0	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,248E5@186801|Clostridia,3XZPC@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	ytvI	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NFNHFNFO_02904	33035.JPJF01000061_gene3660	3.86e-136	386.0	COG0494@1|root,COG0494@2|Bacteria,1V27D@1239|Firmicutes,24GB6@186801|Clostridia,3XZU2@572511|Blautia	186801|Clostridia	L	NUDIX domain	-	-	3.6.1.13	ko:K01515	ko00230,map00230	-	R01054	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX
NFNHFNFO_02905	33035.JPJF01000061_gene3661	1.48e-133	380.0	COG3601@1|root,COG3601@2|Bacteria,1V4BW@1239|Firmicutes,24E4V@186801|Clostridia,3XZK2@572511|Blautia	186801|Clostridia	S	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins	ribU	-	-	-	-	-	-	-	-	-	-	-	ECF_trnsprt
NFNHFNFO_02906	33035.JPJF01000034_gene2840	1.84e-34	120.0	COG2261@1|root,COG2261@2|Bacteria	2|Bacteria	S	Transglycosylase associated protein	ydaS	-	-	-	-	-	-	-	-	-	-	-	Transgly_assoc
NFNHFNFO_02907	33035.JPJF01000034_gene2841	0.0	1191.0	COG3661@1|root,COG3661@2|Bacteria,1UKA3@1239|Firmicutes,24AI6@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolase 67	aguA	-	3.2.1.139	ko:K01235	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_67C,Glyco_hydro_67M,Glyco_hydro_67N
NFNHFNFO_02908	33035.JPJF01000034_gene2843	2.75e-209	578.0	COG0395@1|root,COG0395@2|Bacteria,1TSYB@1239|Firmicutes,24AKM@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_02909	33035.JPJF01000034_gene2844	4.11e-180	504.0	COG1175@1|root,COG1175@2|Bacteria,1TPTZ@1239|Firmicutes,248DR@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_02910	33035.JPJF01000034_gene2845	4.17e-307	840.0	COG1653@1|root,COG1653@2|Bacteria,1TQJV@1239|Firmicutes,24BK1@186801|Clostridia	186801|Clostridia	G	Extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_8
NFNHFNFO_02911	33035.JPJF01000034_gene2846	0.0	1025.0	COG2972@1|root,COG2972@2|Bacteria,1UCQF@1239|Firmicutes,24EY1@186801|Clostridia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
NFNHFNFO_02912	33035.JPJF01000034_gene2847	0.0	954.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UZKW@1239|Firmicutes,249VE@186801|Clostridia	186801|Clostridia	T	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NFNHFNFO_02913	658655.HMPREF0988_02280	7.55e-160	454.0	COG0684@1|root,COG0684@2|Bacteria,1UY1F@1239|Firmicutes,24CQP@186801|Clostridia	186801|Clostridia	H	Aldolase/RraA	-	-	-	-	-	-	-	-	-	-	-	-	RraA-like
NFNHFNFO_02914	97139.C824_02421	2.19e-181	517.0	COG3964@1|root,COG3964@2|Bacteria,1TPXM@1239|Firmicutes,24EFP@186801|Clostridia,36EDQ@31979|Clostridiaceae	186801|Clostridia	S	Amidohydrolase family	-	-	3.5.2.3	ko:K01465	ko00240,ko01100,map00240,map01100	M00051	R01993	RC00632	ko00000,ko00001,ko00002,ko01000	-	-	-	Amidohydro_1,Amidohydro_3
NFNHFNFO_02915	97139.C824_02410	4.15e-72	220.0	COG0251@1|root,COG0251@2|Bacteria,1V6G4@1239|Firmicutes,24IS7@186801|Clostridia,36NSX@31979|Clostridiaceae	186801|Clostridia	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
NFNHFNFO_02916	658655.HMPREF0988_02285	7.01e-86	255.0	COG0251@1|root,COG0251@2|Bacteria,1V6G4@1239|Firmicutes,24IS7@186801|Clostridia,27ST1@186928|unclassified Lachnospiraceae	186801|Clostridia	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
NFNHFNFO_02917	658655.HMPREF0988_02286	5.03e-135	389.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25M56@186801|Clostridia,27RTU@186928|unclassified Lachnospiraceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_02918	658655.HMPREF0988_02287	2.97e-153	436.0	COG1175@1|root,COG1175@2|Bacteria,1TR2A@1239|Firmicutes,247MA@186801|Clostridia,27JA8@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_02919	658655.HMPREF0988_02288	9.26e-201	568.0	COG1653@1|root,COG1653@2|Bacteria,1U4H4@1239|Firmicutes,24A14@186801|Clostridia,27P6A@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02920	658655.HMPREF0988_02289	1.02e-126	376.0	COG2942@1|root,COG2942@2|Bacteria,1TQMG@1239|Firmicutes,24C1F@186801|Clostridia	186801|Clostridia	G	Catalyzes the reversible epimerization of cellobiose to 4-O-beta-D-glucopyranosyl-D-mannose (Glc-Man)	-	-	5.1.3.8	ko:K01787	ko00520,map00520	-	R01207	RC00290	ko00000,ko00001,ko01000	-	-	-	GlcNAc_2-epim
NFNHFNFO_02921	658655.HMPREF0988_02290	1.38e-142	416.0	COG1921@1|root,COG1921@2|Bacteria,1TQT8@1239|Firmicutes,2498U@186801|Clostridia	186801|Clostridia	J	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis	-	-	2.9.1.1,4.3.1.29	ko:K01042,ko:K17468	ko00030,ko00450,ko00970,ko01120,map00030,map00450,map00970,map01120	-	R08219,R10408	RC00544,RC01246	ko00000,ko00001,ko01000	-	-	-	SelA
NFNHFNFO_02922	658655.HMPREF0988_02291	9.87e-110	324.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,27IXU@186928|unclassified Lachnospiraceae	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	1.1.1.100,1.1.1.30	ko:K00019,ko:K00059	ko00061,ko00072,ko00333,ko00650,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00072,map00333,map00650,map00780,map01040,map01100,map01130,map01212	M00083,M00088,M00572	R01361,R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
NFNHFNFO_02923	97139.C824_02414	3.01e-159	456.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,247M2@186801|Clostridia,36F5I@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator, LacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_1,Peripla_BP_3
NFNHFNFO_02924	33035.JPJF01000034_gene2848	3.27e-184	512.0	2DBRG@1|root,2ZAKM@2|Bacteria,1UQ8F@1239|Firmicutes,24CHJ@186801|Clostridia,3XZRT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02925	33035.JPJF01000034_gene2849	3.93e-137	389.0	COG0698@1|root,COG0698@2|Bacteria,1TQQJ@1239|Firmicutes,249IB@186801|Clostridia,3Y1AG@572511|Blautia	186801|Clostridia	G	Ribose-5-phosphate isomerase	-	-	-	-	-	-	-	-	-	-	-	-	DUF3666,LacAB_rpiB
NFNHFNFO_02926	33035.JPJF01000034_gene2850	1.38e-183	511.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia,3XZ8F@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short_C2
NFNHFNFO_02927	33035.JPJF01000034_gene2851	1.19e-199	553.0	COG3717@1|root,COG3717@2|Bacteria,1TP4X@1239|Firmicutes,24A00@186801|Clostridia,3XZQS@572511|Blautia	186801|Clostridia	G	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate	kduI	-	5.3.1.17	ko:K01815	ko00040,map00040	-	R04383	RC00541	ko00000,ko00001,ko01000	-	-	-	KduI
NFNHFNFO_02928	33035.JPJF01000034_gene2852	2.67e-200	555.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1UX6U@1239|Firmicutes,25B1Q@186801|Clostridia,3XZRR@572511|Blautia	186801|Clostridia	K	methylphosphotriester-DNA alkyltransferase (AraC XylS family) K00567	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_02929	33035.JPJF01000034_gene2853	2.45e-44	144.0	COG1925@1|root,COG1925@2|Bacteria,1UHH0@1239|Firmicutes,25Q8A@186801|Clostridia,3Y0VD@572511|Blautia	186801|Clostridia	G	PTS HPr component phosphorylation site	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NFNHFNFO_02930	33035.JPJF01000034_gene2854	0.0	1267.0	COG3533@1|root,COG3533@2|Bacteria,1TNYA@1239|Firmicutes,24841@186801|Clostridia	186801|Clostridia	G	protein conserved in bacteria	-	-	-	ko:K09955	-	-	-	-	ko00000	-	-	-	Glyco_hydro_127
NFNHFNFO_02931	33035.JPJF01000034_gene2855	1.7e-174	490.0	COG2207@1|root,COG2207@2|Bacteria,1VRKI@1239|Firmicutes,24G8Q@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NFNHFNFO_02932	33035.JPJF01000034_gene2856	3.17e-146	421.0	COG0860@1|root,COG0860@2|Bacteria,1UY5Q@1239|Firmicutes,247Y6@186801|Clostridia,3XZ3C@572511|Blautia	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	-	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NFNHFNFO_02933	33035.JPJF01000034_gene2857	7.5e-171	481.0	COG2207@1|root,COG2207@2|Bacteria,1V8DG@1239|Firmicutes,24I38@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_02934	33035.JPJF01000034_gene2858	3.35e-299	817.0	COG3345@1|root,COG3345@2|Bacteria,1TQ3Q@1239|Firmicutes,25E9S@186801|Clostridia	186801|Clostridia	G	Alpha galactosidase A	-	-	-	-	-	-	-	-	-	-	-	-	Melibiase_2
NFNHFNFO_02935	1226325.HMPREF1548_02252	9.61e-243	685.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,36E5J@31979|Clostridiaceae	186801|Clostridia	K	An automated process has identified a potential problem with this gene model	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NFNHFNFO_02936	33035.JPJF01000034_gene2859	0.0	1073.0	COG4289@1|root,COG4289@2|Bacteria,1TSHI@1239|Firmicutes,24C95@186801|Clostridia	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2264)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2264
NFNHFNFO_02937	33035.JPJF01000034_gene2860	8.09e-283	771.0	COG1331@1|root,COG1331@2|Bacteria,1TQ83@1239|Firmicutes,24ZNJ@186801|Clostridia	186801|Clostridia	O	Unsaturated glucuronyl hydrolase	-	-	3.2.1.180	ko:K18581	-	-	R10867	RC00049,RC02427	ko00000,ko01000	-	GH88	-	Glyco_hydro_88
NFNHFNFO_02938	33035.JPJF01000034_gene2861	0.0	2077.0	COG3507@1|root,COG3534@1|root,COG3507@2|Bacteria,COG3534@2|Bacteria,1TPG2@1239|Firmicutes,24AVP@186801|Clostridia	186801|Clostridia	G	Alpha-L-arabinofuranosidase C-terminus	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,Cadherin-like
NFNHFNFO_02939	33035.JPJF01000034_gene2862	1.29e-213	591.0	COG5492@1|root,COG5492@2|Bacteria,1TW7Y@1239|Firmicutes,24AP8@186801|Clostridia	186801|Clostridia	N	domain, Protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02940	33035.JPJF01000034_gene2863	0.0	1537.0	COG3250@1|root,COG3250@2|Bacteria,1TPK7@1239|Firmicutes,247VE@186801|Clostridia,3XZFJ@572511|Blautia	186801|Clostridia	G	Domain of unknown function (DUF4982)	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Big_4,DUF4982,F5_F8_type_C,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFNHFNFO_02941	33035.JPJF01000034_gene2865	3.84e-312	852.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3XYQN@572511|Blautia	186801|Clostridia	V	MatE	-	-	-	ko:K03327	-	-	-	-	ko00000,ko02000	2.A.66.1	-	-	MatE
NFNHFNFO_02942	33035.JPJF01000034_gene2866	4.13e-140	397.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,3XZV2@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_02943	33035.JPJF01000034_gene2867	5.39e-129	371.0	28ZKB@1|root,2ZMBN@2|Bacteria,1V2FX@1239|Firmicutes,24DMT@186801|Clostridia,3Y0U1@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02944	33035.JPJF01000034_gene2868	1.01e-167	470.0	2BQS3@1|root,32JNS@2|Bacteria,1U2HH@1239|Firmicutes,25IPM@186801|Clostridia,3Y20X@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02945	33035.JPJF01000034_gene2869	6.88e-242	668.0	2E29B@1|root,32XF1@2|Bacteria,1VDSY@1239|Firmicutes,25IV0@186801|Clostridia,3Y24R@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02948	397291.C804_05739	5.05e-41	155.0	COG4219@1|root,COG4219@2|Bacteria,1V2TD@1239|Firmicutes,25BGN@186801|Clostridia,27PYU@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
NFNHFNFO_02950	33035.JPJF01000034_gene2871	8.61e-223	614.0	COG2207@1|root,COG2207@2|Bacteria,1V3FC@1239|Firmicutes,24C4C@186801|Clostridia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_02951	33035.JPJF01000034_gene2872	0.0	1160.0	COG1874@1|root,COG1874@2|Bacteria,1TSHK@1239|Firmicutes,249IJ@186801|Clostridia	186801|Clostridia	G	beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_35
NFNHFNFO_02952	33035.JPJF01000034_gene2873	0.0	1032.0	COG1653@1|root,COG1653@2|Bacteria,1TS6H@1239|Firmicutes,24BIJ@186801|Clostridia	186801|Clostridia	G	Domain of unknown function (DUF3502)	-	-	-	ko:K17318	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	DUF3502,SBP_bac_1
NFNHFNFO_02953	33035.JPJF01000034_gene2874	4.63e-200	556.0	COG0395@1|root,COG0395@2|Bacteria,1TS9S@1239|Firmicutes,24BF3@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026,ko:K17320	ko02010,map02010	M00207,M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NFNHFNFO_02954	33035.JPJF01000034_gene2875	1.01e-216	599.0	COG4209@1|root,COG4209@2|Bacteria,1TT63@1239|Firmicutes,25C4W@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K17319	ko02010,map02010	M00603	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.29,3.A.1.1.9	-	-	BPD_transp_1
NFNHFNFO_02955	33035.JPJF01000034_gene2876	1.17e-225	624.0	COG1609@1|root,COG1609@2|Bacteria,1TQ7K@1239|Firmicutes,249FN@186801|Clostridia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_02956	33035.JPJF01000034_gene2877	1.64e-155	438.0	COG4753@1|root,COG4753@2|Bacteria,1URF2@1239|Firmicutes,24KCB@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_02957	33035.JPJF01000034_gene2878	0.0	992.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3XZ6E@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NFNHFNFO_02958	33035.JPJF01000034_gene2879	0.0	964.0	COG1653@1|root,COG1653@2|Bacteria,1UYZC@1239|Firmicutes,24CMN@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_02959	33035.JPJF01000034_gene2882	0.0	1148.0	COG0006@1|root,COG0006@2|Bacteria,1TQ44@1239|Firmicutes,247SG@186801|Clostridia,3XYH3@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	pepQ	-	3.4.11.9	ko:K01262	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Creatinase_N,Creatinase_N_2,Peptidase_M24,Peptidase_M24_C
NFNHFNFO_02960	33035.JPJF01000034_gene2883	0.0	1335.0	COG2183@1|root,COG2183@2|Bacteria,1TPFE@1239|Firmicutes,248P0@186801|Clostridia,3XYW2@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	yhgF	-	-	ko:K06959	-	-	-	-	ko00000	-	-	-	HHH_3,S1,Tex_N,Tex_YqgF
NFNHFNFO_02961	33035.JPJF01000034_gene2884	0.0	909.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3XYSC@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	xylB	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_02962	1235800.C819_02823	1.5e-32	125.0	2FEI3@1|root,346HK@2|Bacteria,1W0JF@1239|Firmicutes,253M0@186801|Clostridia,27SKP@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02963	33035.JPJF01000034_gene2886	8.48e-110	319.0	29WCS@1|root,30HYF@2|Bacteria,1US0F@1239|Firmicutes,259YE@186801|Clostridia,3Y1XC@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02964	33035.JPJF01000034_gene2887	9.42e-80	238.0	2DNZJ@1|root,32ZX7@2|Bacteria,1VHMI@1239|Firmicutes,24SBG@186801|Clostridia,3Y0VH@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF2752)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2752
NFNHFNFO_02965	33035.JPJF01000034_gene2888	6.41e-164	461.0	COG5523@1|root,COG5523@2|Bacteria,1VB3B@1239|Firmicutes,24N6Q@186801|Clostridia,3Y0AG@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
NFNHFNFO_02967	33035.JPJF01000034_gene2890	4.35e-189	550.0	COG1361@1|root,COG1361@2|Bacteria,1TQHN@1239|Firmicutes,24BUH@186801|Clostridia,3Y0PV@572511|Blautia	186801|Clostridia	M	COG NOG29868 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	CARDB
NFNHFNFO_02968	33035.JPJF01000034_gene2891	2.7e-132	379.0	COG1131@1|root,COG1131@2|Bacteria,1V1P4@1239|Firmicutes,249VI@186801|Clostridia,3XZV2@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_02969	33035.JPJF01000034_gene2892	5.88e-125	360.0	2C82F@1|root,32X5P@2|Bacteria,1VC9W@1239|Firmicutes,24PT0@186801|Clostridia,3Y1TW@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02970	33035.JPJF01000034_gene2893	3.05e-163	462.0	28ITJ@1|root,2Z8SG@2|Bacteria,1V0TD@1239|Firmicutes,24AI9@186801|Clostridia,3Y182@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02971	33035.JPJF01000034_gene2894	1.09e-184	532.0	2CGG8@1|root,33288@2|Bacteria,1VR70@1239|Firmicutes,25E2I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02972	33035.JPJF01000006_gene2072	1.49e-189	542.0	COG0642@1|root,COG2205@2|Bacteria,1TRD2@1239|Firmicutes,247M3@186801|Clostridia,3Y0A6@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NFNHFNFO_02973	33035.JPJF01000006_gene2073	9.19e-115	333.0	COG0745@1|root,COG0745@2|Bacteria,1TQSA@1239|Firmicutes,24F54@186801|Clostridia,3Y2DR@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_02974	478749.BRYFOR_08164	9.02e-137	390.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia	186801|Clostridia	G	L-ribulose-5-phosphate 4-epimerase	-	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
NFNHFNFO_02975	1232453.BAIF02000062_gene1908	3e-120	352.0	COG3623@1|root,COG3623@2|Bacteria,1TSMS@1239|Firmicutes,247T6@186801|Clostridia	186801|Clostridia	G	hexulose-6-phosphate isomerase	ulaE	-	5.1.3.22	ko:K03079	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R03244	RC00540	ko00000,ko00001,ko00002,ko01000	-	-	-	AP_endonuc_2
NFNHFNFO_02976	1280706.AUJE01000013_gene1768	1.63e-158	454.0	28IPH@1|root,2Z8PG@2|Bacteria,1TREB@1239|Firmicutes,4H4A2@909932|Negativicutes	909932|Negativicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02977	1121115.AXVN01000038_gene3340	1.36e-268	734.0	COG2220@1|root,COG2220@2|Bacteria,1TSFV@1239|Firmicutes,249MG@186801|Clostridia,3Y1A5@572511|Blautia	186801|Clostridia	S	Beta-lactamase superfamily domain	ulaG	-	-	ko:K03476	ko00053,ko01100,ko01120,map00053,map01100,map01120	M00550	R07677	RC02793	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactamase_B_2,Lactamase_B_3
NFNHFNFO_02978	1121115.AXVN01000038_gene3341	4.07e-156	460.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3XZDA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.17,2.7.1.30	ko:K00854,ko:K00864	ko00040,ko00561,ko01100,ko03320,ko04626,map00040,map00561,map01100,map03320,map04626	M00014	R00847,R01639	RC00002,RC00017,RC00538	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_02979	383381.EH30_13410	0.000482	48.9	COG0491@1|root,COG0491@2|Bacteria,1MURA@1224|Proteobacteria,2TR1F@28211|Alphaproteobacteria,2K06J@204457|Sphingomonadales	204457|Sphingomonadales	S	COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
NFNHFNFO_02980	1132442.KB889752_gene3267	9.87e-27	117.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,4HBHB@91061|Bacilli,1ZANH@1386|Bacillus	91061|Bacilli	G	6-phosphogluconolactonase	pgl	GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016787,GO:0016788,GO:0017057,GO:0044424,GO:0044444,GO:0044464,GO:0052689	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
NFNHFNFO_02981	1123075.AUDP01000029_gene2177	1.16e-76	259.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3WK3M@541000|Ruminococcaceae	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_5
NFNHFNFO_02982	1123075.AUDP01000029_gene2178	2.66e-141	409.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3WGUX@541000|Ruminococcaceae	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NFNHFNFO_02983	1123075.AUDP01000029_gene2179	2.45e-146	422.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3WGTC@541000|Ruminococcaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NFNHFNFO_02984	1123075.AUDP01000029_gene2180	4.66e-101	303.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3WJDM@541000|Ruminococcaceae	186801|Clostridia	EP	ABC-type dipeptide oligopeptide nickel transport systems, permease components	appC	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1,OppC_N
NFNHFNFO_02985	1123075.AUDP01000029_gene2181	2.52e-100	305.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3WIW6@541000|Ruminococcaceae	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NFNHFNFO_02987	1089545.KB913037_gene738	5.9e-104	306.0	2EXVQ@1|root,33R4U@2|Bacteria,2IDZ0@201174|Actinobacteria	201174|Actinobacteria	S	SnoaL-like domain	-	-	-	-	-	-	-	-	-	-	-	-	SnoaL_4
NFNHFNFO_02988	1452536.JARE01000031_gene965	4.2e-36	135.0	COG1028@1|root,COG1028@2|Bacteria,2INZY@201174|Actinobacteria	201174|Actinobacteria	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NFNHFNFO_02989	1128421.JAGA01000003_gene3306	3.82e-36	139.0	COG2390@1|root,COG2390@2|Bacteria,2NQXC@2323|unclassified Bacteria	2|Bacteria	K	Putative sugar-binding domain	lsrR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,HTH_28,Sigma70_r4,Sugar-bind
NFNHFNFO_02990	33035.JPJF01000006_gene2079	2.76e-264	726.0	COG3635@1|root,COG3635@2|Bacteria,1TQ5S@1239|Firmicutes,248U6@186801|Clostridia,3XZDS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	5.4.2.12	ko:K15635	ko00010,ko00260,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00260,map00680,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01518	RC00536	ko00000,ko00001,ko00002,ko01000	-	-	-	Metalloenzyme,PhosphMutase
NFNHFNFO_02991	33035.JPJF01000006_gene2080	8.56e-289	789.0	COG0460@1|root,COG0460@2|Bacteria,1TQ2H@1239|Firmicutes,248MU@186801|Clostridia,3XYWS@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hom	-	1.1.1.3	ko:K00003	ko00260,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map00270,map00300,map01100,map01110,map01120,map01130,map01230	M00017,M00018	R01773,R01775	RC00087	ko00000,ko00001,ko00002,ko01000	-	-	-	Homoserine_dh,NAD_binding_3
NFNHFNFO_02992	33035.JPJF01000006_gene2081	4.75e-96	280.0	COG4492@1|root,COG4492@2|Bacteria,1VAJ9@1239|Firmicutes,24MTS@186801|Clostridia,3XZTJ@572511|Blautia	186801|Clostridia	S	Belongs to the UPF0735 family	pheB	-	5.4.99.5	ko:K06209	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00024,M00025	R01715	RC03116	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_4
NFNHFNFO_02993	33035.JPJF01000006_gene2082	1.4e-237	653.0	COG1186@1|root,COG1186@2|Bacteria,1TPSB@1239|Firmicutes,247KU@186801|Clostridia,3XZ5R@572511|Blautia	186801|Clostridia	J	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA	prfB	-	-	ko:K02836	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
NFNHFNFO_02994	537007.BLAHAN_04079	2.28e-40	134.0	2E7JQ@1|root,3321V@2|Bacteria,1VH9B@1239|Firmicutes,24S3M@186801|Clostridia,3Y0WH@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_02995	33035.JPJF01000006_gene2084	0.0	1622.0	COG0653@1|root,COG0653@2|Bacteria,1TPEY@1239|Firmicutes,247N2@186801|Clostridia,3XYPH@572511|Blautia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane	secA	-	-	ko:K03070	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	3.A.5.1,3.A.5.10,3.A.5.2,3.A.5.4	-	-	Helicase_C,SEC-C,SecA_DEAD,SecA_PP_bind,SecA_SW
NFNHFNFO_02996	33035.JPJF01000006_gene2085	1.84e-219	608.0	COG2188@1|root,COG2188@2|Bacteria,1TS1M@1239|Firmicutes,24CNY@186801|Clostridia	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
NFNHFNFO_02997	33035.JPJF01000006_gene2086	0.0	1321.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3XYX5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NFNHFNFO_02998	33035.JPJF01000006_gene2087	4.36e-289	793.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia,3XZJC@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	lacE	-	-	ko:K10188	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_02999	698758.AXY_05150	2.09e-131	380.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1TPI9@1239|Firmicutes,4HCJ8@91061|Bacilli	91061|Bacilli	K	AraC family transcriptional regulator	ydeE7	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,GyrI-like,HTH_18
NFNHFNFO_03000	33035.JPJF01000006_gene2088	1.56e-121	347.0	COG1544@1|root,COG1544@2|Bacteria,1V1D5@1239|Firmicutes,24HDH@186801|Clostridia,3XZRY@572511|Blautia	186801|Clostridia	J	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase	hpf	-	-	ko:K05808	-	-	-	-	ko00000,ko03009	-	-	-	Ribosom_S30AE_C,Ribosomal_S30AE
NFNHFNFO_03001	33035.JPJF01000006_gene2089	1.21e-20	89.4	2C115@1|root,33J4D@2|Bacteria,1VQ7Z@1239|Firmicutes,24X7I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03002	33035.JPJF01000003_gene1836	4.83e-169	473.0	COG0289@1|root,COG0289@2|Bacteria,1TR9D@1239|Firmicutes,248FY@186801|Clostridia,3XZD1@572511|Blautia	186801|Clostridia	E	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate	dapB	-	1.17.1.8	ko:K00215	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R04198,R04199	RC00478	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS17035	DapB_C,DapB_N
NFNHFNFO_03003	33035.JPJF01000003_gene1837	1.06e-202	562.0	COG0329@1|root,COG0329@2|Bacteria,1TPCK@1239|Firmicutes,247T5@186801|Clostridia,3XZIM@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)	dapA	-	4.3.3.7	ko:K01714	ko00261,ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00261,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R10147	RC03062,RC03063	ko00000,ko00001,ko00002,ko01000	-	-	-	DHDPS
NFNHFNFO_03004	33035.JPJF01000003_gene1838	1.8e-105	305.0	COG2109@1|root,COG2109@2|Bacteria,1V82Z@1239|Firmicutes,24J8J@186801|Clostridia,3Y0A2@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score	btuR	-	2.5.1.17	ko:K19221	ko00860,ko01100,map00860,map01100	M00122	R01492,R05220,R07268	RC00533	ko00000,ko00001,ko00002,ko01000	-	-	-	CobA_CobO_BtuR
NFNHFNFO_03005	33035.JPJF01000003_gene1839	1.85e-139	394.0	COG0629@1|root,COG0629@2|Bacteria,1TRWZ@1239|Firmicutes,248UD@186801|Clostridia,3XZI3@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ssb1	-	-	-	-	-	-	-	-	-	-	-	SSB
NFNHFNFO_03006	33035.JPJF01000003_gene1840	0.0	1173.0	COG1217@1|root,COG1217@2|Bacteria,1TQ5Y@1239|Firmicutes,248EB@186801|Clostridia,3XYY0@572511|Blautia	186801|Clostridia	T	GTP-binding protein TypA BipA homolog	typA	-	-	ko:K06207	-	-	-	-	ko00000	-	-	-	EFG_C,EFG_II,GTP_EFTU,GTP_EFTU_D2
NFNHFNFO_03007	33035.JPJF01000003_gene1841	0.0	1699.0	COG1012@1|root,COG1454@1|root,COG1012@2|Bacteria,COG1454@2|Bacteria,1TPB4@1239|Firmicutes,247IQ@186801|Clostridia,3XYZE@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	adhE	-	1.1.1.1,1.2.1.10	ko:K04072	ko00010,ko00071,ko00350,ko00620,ko00625,ko00626,ko00650,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00620,map00625,map00626,map00650,map01100,map01110,map01120,map01130,map01220	-	R00228,R00623,R00754,R01172,R04880,R05233,R05234,R06917,R06927	RC00004,RC00050,RC00088,RC00099,RC00116,RC00184,RC00649,RC01195	ko00000,ko00001,ko01000	-	-	-	Aldedh,Fe-ADH
NFNHFNFO_03008	33035.JPJF01000003_gene1842	1.68e-111	322.0	COG0311@1|root,COG0311@2|Bacteria,1V3I6@1239|Firmicutes,24HRT@186801|Clostridia,3Y1IT@572511|Blautia	186801|Clostridia	H	SNO glutamine amidotransferase family	pdxT	-	4.3.3.6	ko:K08681	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS19495	SNO
NFNHFNFO_03009	33035.JPJF01000003_gene1843	1.73e-189	528.0	COG0214@1|root,COG0214@2|Bacteria,1TPSZ@1239|Firmicutes,248C1@186801|Clostridia,3Y0X6@572511|Blautia	186801|Clostridia	H	SOR/SNZ family	pdxS	-	4.3.3.6	ko:K06215	ko00750,map00750	-	R07456	RC00010,RC01783,RC03043	ko00000,ko00001,ko01000	-	-	-	SOR_SNZ
NFNHFNFO_03010	33035.JPJF01000003_gene1844	1.64e-211	591.0	COG0726@1|root,COG0726@2|Bacteria,1V6DN@1239|Firmicutes,249SN@186801|Clostridia,3XYJW@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.5.1.104	ko:K22278	-	-	-	-	ko00000,ko01000	-	-	-	CW_binding_1,ChW,Polysacc_deac_1
NFNHFNFO_03011	33035.JPJF01000003_gene1845	3.71e-314	861.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZM1@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	agcS	-	-	ko:K03310	-	-	-	-	ko00000	2.A.25	-	-	Na_Ala_symp
NFNHFNFO_03012	33035.JPJF01000003_gene1846	4.08e-255	703.0	COG1301@1|root,COG1301@2|Bacteria,1TP4N@1239|Firmicutes,2494N@186801|Clostridia,3XYHS@572511|Blautia	186801|Clostridia	P	Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family	-	-	-	-	-	-	-	-	-	-	-	-	SDF
NFNHFNFO_03013	33035.JPJF01000003_gene1847	3.2e-118	339.0	COG1971@1|root,COG1971@2|Bacteria,1V4QK@1239|Firmicutes,24FY0@186801|Clostridia,3Y01B@572511|Blautia	186801|Clostridia	P	Probably functions as a manganese efflux pump	mntP	-	-	-	-	-	-	-	-	-	-	-	Mntp
NFNHFNFO_03014	33035.JPJF01000003_gene1848	0.0	1058.0	COG3507@1|root,COG3507@2|Bacteria,1TP5K@1239|Firmicutes,247R2@186801|Clostridia,3Y197@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 43	-	-	3.2.1.37,3.2.1.55	ko:K01198,ko:K01209	ko00520,ko01100,map00520,map01100	-	R01433,R01762	RC00467	ko00000,ko00001,ko01000	-	GH43,GH51	-	Glyco_hydro_43
NFNHFNFO_03015	33035.JPJF01000003_gene1849	1.01e-143	406.0	COG4845@1|root,COG4845@2|Bacteria,1W19F@1239|Firmicutes,252N8@186801|Clostridia	186801|Clostridia	V	Chloramphenicol acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	CAT
NFNHFNFO_03016	33035.JPJF01000003_gene1850	3.31e-141	399.0	COG4905@1|root,COG4905@2|Bacteria,1TQHG@1239|Firmicutes,2485W@186801|Clostridia,3Y1BV@572511|Blautia	186801|Clostridia	S	Putative ABC-transporter type IV	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB,DUF975
NFNHFNFO_03017	33035.JPJF01000003_gene1852	3.45e-230	637.0	COG0642@1|root,COG2205@2|Bacteria,1VRNY@1239|Firmicutes,24EZG@186801|Clostridia,3Y1KA@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_03018	33035.JPJF01000003_gene1853	3e-139	395.0	COG0745@1|root,COG0745@2|Bacteria,1TT73@1239|Firmicutes,2487E@186801|Clostridia,3Y1GZ@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_03019	33035.JPJF01000003_gene1854	1.75e-105	307.0	2F69Y@1|root,30GG7@2|Bacteria,1UFZ7@1239|Firmicutes,25N1D@186801|Clostridia,3Y20P@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03020	33035.JPJF01000003_gene1858	2.06e-185	522.0	2BP77@1|root,32HYI@2|Bacteria,1V84J@1239|Firmicutes,24JDS@186801|Clostridia,3Y1EA@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03021	33035.JPJF01000003_gene1859	0.0	1372.0	COG1472@1|root,COG1472@2|Bacteria,1TP0T@1239|Firmicutes,24932@186801|Clostridia,3XZXF@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NFNHFNFO_03022	33035.JPJF01000003_gene1860	0.0	961.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TRXY@1239|Firmicutes,24BYW@186801|Clostridia,3Y1D5@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NFNHFNFO_03023	33035.JPJF01000003_gene1861	0.0	1101.0	COG2972@1|root,COG2972@2|Bacteria,1UYIY@1239|Firmicutes,24ACA@186801|Clostridia,3Y1EM@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,dCache_1
NFNHFNFO_03024	33035.JPJF01000003_gene1862	4.82e-192	534.0	COG0395@1|root,COG0395@2|Bacteria,1TRD1@1239|Firmicutes,24BQQ@186801|Clostridia,3Y16U@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_03025	33035.JPJF01000003_gene1863	9.91e-210	580.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3Y0XA@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_03026	33035.JPJF01000003_gene1864	1.69e-310	848.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24C14@186801|Clostridia,3Y189@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_03027	33035.JPJF01000003_gene1865	4.89e-287	789.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24C14@186801|Clostridia	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_03028	33035.JPJF01000003_gene1866	2.59e-200	566.0	COG1277@1|root,COG1277@2|Bacteria,1TSXC@1239|Firmicutes,24CZ4@186801|Clostridia,3Y0PT@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
NFNHFNFO_03029	33035.JPJF01000003_gene1867	8.14e-175	491.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3XZE4@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_03030	33035.JPJF01000003_gene1868	2.93e-86	264.0	2CJ98@1|root,326JR@2|Bacteria,1V6JM@1239|Firmicutes,24KX0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03031	33035.JPJF01000003_gene1869	1.16e-104	304.0	COG1595@1|root,COG1595@2|Bacteria,1TS3M@1239|Firmicutes,25B0U@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_03032	33035.JPJF01000061_gene3671	1.79e-30	121.0	2DWV7@1|root,3421J@2|Bacteria,1VX8N@1239|Firmicutes,251PW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03033	33035.JPJF01000003_gene1871	0.0	3539.0	COG1409@1|root,COG2366@1|root,COG5434@1|root,COG1409@2|Bacteria,COG2366@2|Bacteria,COG5434@2|Bacteria,1V0G8@1239|Firmicutes,25B0V@186801|Clostridia	186801|Clostridia	M	F5/8 type C domain	-	-	-	-	-	-	-	-	-	-	-	-	F5_F8_type_C,FIVAR,Malectin
NFNHFNFO_03034	33035.JPJF01000003_gene1872	2.42e-137	393.0	2DNA2@1|root,32WD5@2|Bacteria,1VDP6@1239|Firmicutes,24Q7U@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03035	33035.JPJF01000003_gene1873	5.5e-42	138.0	COG2732@1|root,COG2732@2|Bacteria,1VM0Z@1239|Firmicutes	1239|Firmicutes	K	Barnase inhibitor	-	-	-	ko:K03623	-	-	-	-	ko00000	-	-	-	Barstar
NFNHFNFO_03036	33035.JPJF01000003_gene1874	8.27e-102	297.0	COG4290@1|root,COG4290@2|Bacteria,1V7IV@1239|Firmicutes,24JGG@186801|Clostridia	186801|Clostridia	F	Ribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	Ribonuclease
NFNHFNFO_03037	33035.JPJF01000003_gene1875	5.58e-167	470.0	COG0561@1|root,COG0561@2|Bacteria,1U3W2@1239|Firmicutes,2486H@186801|Clostridia,3Y0BQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NFNHFNFO_03038	33035.JPJF01000003_gene1876	6.09e-70	211.0	COG1694@1|root,COG1694@2|Bacteria,1VA3E@1239|Firmicutes,24NYY@186801|Clostridia	186801|Clostridia	S	MazG nucleotide pyrophosphohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	MazG-like
NFNHFNFO_03039	33035.JPJF01000003_gene1877	0.0	1147.0	COG0840@1|root,COG2199@1|root,COG0840@2|Bacteria,COG2199@2|Bacteria,1TQG9@1239|Firmicutes,249KA@186801|Clostridia,3Y0T6@572511|Blautia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NFNHFNFO_03040	33035.JPJF01000003_gene1878	1.56e-189	527.0	COG1073@1|root,COG1073@2|Bacteria,1UHZK@1239|Firmicutes,25E87@186801|Clostridia	186801|Clostridia	S	Hydrolase, alpha beta domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
NFNHFNFO_03041	33035.JPJF01000003_gene1879	7.96e-264	728.0	COG2271@1|root,COG2271@2|Bacteria,1TQZE@1239|Firmicutes,25E40@186801|Clostridia,3Y11P@572511|Blautia	186801|Clostridia	G	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NFNHFNFO_03042	33035.JPJF01000003_gene1880	2.1e-139	397.0	29UNA@1|root,30FZX@2|Bacteria,1UEXX@1239|Firmicutes,25JXK@186801|Clostridia,3Y1Y6@572511|Blautia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03043	33035.JPJF01000003_gene1881	4.72e-152	429.0	COG1131@1|root,COG1131@2|Bacteria,1VSFC@1239|Firmicutes,24ZTT@186801|Clostridia,3Y1JN@572511|Blautia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_03044	33035.JPJF01000003_gene1882	1.12e-135	386.0	COG1309@1|root,COG1309@2|Bacteria,1TWE4@1239|Firmicutes,24C3H@186801|Clostridia,3Y1JV@572511|Blautia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_03045	33035.JPJF01000003_gene1883	1.02e-294	808.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYKT@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_03046	33035.JPJF01000003_gene1884	2.01e-102	297.0	COG0454@1|root,COG0456@2|Bacteria,1V4FY@1239|Firmicutes,25E88@186801|Clostridia	186801|Clostridia	K	Acetyltransferase, gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_9
NFNHFNFO_03047	33035.JPJF01000003_gene1885	0.0	940.0	COG0737@1|root,COG0737@2|Bacteria,1TPV2@1239|Firmicutes,2491Y@186801|Clostridia,3Y0K5@572511|Blautia	186801|Clostridia	F	5'-nucleotidase, C-terminal domain	-	-	3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45	ko:K01119,ko:K11751	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R00183,R00511,R00963,R01126,R01227,R01562,R01569,R01664,R01877,R01968,R02088,R02102,R02148,R02323,R02370,R02719,R03346,R03537,R03538,R03929,R05135	RC00017,RC00078,RC00296	ko00000,ko00001,ko01000	-	-	-	5_nucleotid_C,Metallophos
NFNHFNFO_03048	33035.JPJF01000003_gene1886	8.47e-211	615.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,1TP9P@1239|Firmicutes,2485B@186801|Clostridia,3XZ3T@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PHP_C
NFNHFNFO_03049	33035.JPJF01000003_gene1886	0.0	1244.0	COG0210@1|root,COG1379@1|root,COG0210@2|Bacteria,COG1379@2|Bacteria,1TP9P@1239|Firmicutes,2485B@186801|Clostridia,3XZ3T@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	PHP_C
NFNHFNFO_03050	908340.HMPREF9406_2753	6.49e-164	469.0	COG2207@1|root,COG2207@2|Bacteria,1TRJ9@1239|Firmicutes,24BAP@186801|Clostridia,36FMR@31979|Clostridiaceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NFNHFNFO_03051	1280689.AUJC01000015_gene5	0.0	1073.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,36EGZ@31979|Clostridiaceae	186801|Clostridia	C	NADH flavin oxidoreductase NADH oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Oxidored_FMN,Pyr_redox_2
NFNHFNFO_03052	684719.HIMB114_00000120	3.23e-16	81.3	COG2364@1|root,COG2364@2|Bacteria,1QZWW@1224|Proteobacteria,2U6M8@28211|Alphaproteobacteria,4BQME@82117|unclassified Alphaproteobacteria	28211|Alphaproteobacteria	S	membrane	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	YitT_membrane
NFNHFNFO_03053	1105031.HMPREF1141_1166	3.65e-100	298.0	COG0813@1|root,COG0813@2|Bacteria,1TQPG@1239|Firmicutes,248G6@186801|Clostridia,36DR4@31979|Clostridiaceae	186801|Clostridia	F	Purine nucleoside phosphorylase	deoD	-	2.4.2.1	ko:K03784	ko00230,ko00240,ko00760,ko01100,ko01110,map00230,map00240,map00760,map01100,map01110	-	R01561,R01863,R01969,R02147,R02294,R02295,R02297,R02484,R02557,R02748,R08368,R10244	RC00033,RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	PNP_UDP_1
NFNHFNFO_03054	246194.CHY_1963	3.81e-149	434.0	COG1015@1|root,COG1015@2|Bacteria,1TP70@1239|Firmicutes,247WB@186801|Clostridia,42F24@68295|Thermoanaerobacterales	186801|Clostridia	G	Phosphotransfer between the C1 and C5 carbon atoms of pentose	deoB	-	5.4.2.7	ko:K01839	ko00030,ko00230,map00030,map00230	-	R01057,R02749	RC00408	ko00000,ko00001,ko01000	-	-	-	Metalloenzyme
NFNHFNFO_03055	457421.CBFG_03846	6.57e-131	384.0	COG1816@1|root,COG1816@2|Bacteria,1U44B@1239|Firmicutes,247KD@186801|Clostridia	186801|Clostridia	F	adenosine deaminase	add	-	3.5.4.4	ko:K01488	ko00230,ko01100,ko05340,map00230,map01100,map05340	-	R01560,R02556	RC00477	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS13960	A_deaminase
NFNHFNFO_03056	457421.CBFG_03845	4.65e-142	407.0	COG1912@1|root,COG1912@2|Bacteria,1TSR3@1239|Firmicutes,24D3T@186801|Clostridia	186801|Clostridia	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
NFNHFNFO_03057	457421.CBFG_03844	3.91e-160	453.0	COG1912@1|root,COG1912@2|Bacteria,1TSR3@1239|Firmicutes,24D3T@186801|Clostridia	186801|Clostridia	S	S-adenosyl-l-methionine hydroxide adenosyltransferase	-	-	-	ko:K22205	-	-	-	-	ko00000,ko01000	-	-	-	SAM_adeno_trans
NFNHFNFO_03058	457421.CBFG_03843	1.86e-243	680.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
NFNHFNFO_03059	457421.CBFG_03842	2.5e-79	248.0	COG3393@1|root,COG3393@2|Bacteria,1UFJG@1239|Firmicutes,24K1G@186801|Clostridia	186801|Clostridia	K	PFAM GCN5-related N-acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03061	457421.CBFG_03841	2.12e-103	306.0	COG2188@1|root,COG2188@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	ymfC	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
NFNHFNFO_03062	411470.RUMGNA_00405	6.6e-145	421.0	COG4607@1|root,COG4607@2|Bacteria,1UXCZ@1239|Firmicutes,2490M@186801|Clostridia	186801|Clostridia	P	periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	Peripla_BP_2
NFNHFNFO_03063	478749.BRYFOR_08843	5.19e-62	196.0	COG4604@1|root,COG4604@2|Bacteria,1UHP5@1239|Firmicutes,25EJF@186801|Clostridia	186801|Clostridia	P	ABC-type enterochelin transport system, ATPase component	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
NFNHFNFO_03064	658088.HMPREF0987_01779	4.37e-68	213.0	COG4604@1|root,COG4604@2|Bacteria,1UHP5@1239|Firmicutes,25EJF@186801|Clostridia	186801|Clostridia	P	ABC-type enterochelin transport system, ATPase component	-	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
NFNHFNFO_03065	1203606.HMPREF1526_01155	4.23e-166	472.0	COG4605@1|root,COG4605@2|Bacteria,1TP3V@1239|Firmicutes,24ATQ@186801|Clostridia,36FVU@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NFNHFNFO_03066	478749.BRYFOR_08841	3.35e-184	520.0	COG4606@1|root,COG4606@2|Bacteria,1TSQX@1239|Firmicutes,249JQ@186801|Clostridia	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NFNHFNFO_03067	411470.RUMGNA_00409	4.08e-08	53.5	COG1733@1|root,COG1733@2|Bacteria	2|Bacteria	K	regulation of RNA biosynthetic process	-	-	-	-	-	-	-	-	-	-	-	-	HxlR
NFNHFNFO_03068	478749.BRYFOR_06499	7.77e-60	187.0	COG4725@1|root,COG4725@2|Bacteria,1TSJV@1239|Firmicutes,248X5@186801|Clostridia	186801|Clostridia	KT	Belongs to the MT-A70-like family	-	-	-	-	-	-	-	-	-	-	-	-	MT-A70
NFNHFNFO_03069	33035.JPJF01000081_gene257	0.0	1597.0	COG3451@1|root,COG3451@2|Bacteria,1TPDR@1239|Firmicutes,248ND@186801|Clostridia,3XZH0@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_10,DUF87
NFNHFNFO_03070	478749.BRYFOR_06502	0.0	1567.0	COG0739@1|root,COG0791@1|root,COG0739@2|Bacteria,COG0791@2|Bacteria,1TP24@1239|Firmicutes,247K5@186801|Clostridia	186801|Clostridia	M	NlpC p60 family protein	-	-	-	-	-	-	-	-	-	-	-	-	NLPC_P60,Peptidase_M23
NFNHFNFO_03071	478749.BRYFOR_06503	1.59e-45	147.0	2CV8V@1|root,32SX5@2|Bacteria,1VCY8@1239|Firmicutes,24NEP@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF4315)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4315
NFNHFNFO_03072	33035.JPJF01000081_gene253	7.25e-213	596.0	28HUZ@1|root,2Z81G@2|Bacteria,1TS04@1239|Firmicutes,24AUT@186801|Clostridia,3Y0I7@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4366)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4366
NFNHFNFO_03073	33035.JPJF01000081_gene252	0.0	3073.0	COG4509@1|root,COG4932@1|root,COG4509@2|Bacteria,COG4932@2|Bacteria,1TRG6@1239|Firmicutes,2492K@186801|Clostridia,3Y0YX@572511|Blautia	186801|Clostridia	M	Sortase family	-	-	-	-	-	-	-	-	-	-	-	-	Sortase
NFNHFNFO_03074	33035.JPJF01000081_gene251	1.38e-117	335.0	28M7U@1|root,2ZAM5@2|Bacteria,1V0W4@1239|Firmicutes,24BGD@186801|Clostridia,3Y17D@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03075	1232447.BAHW02000044_gene2851	3.65e-130	371.0	COG5340@1|root,COG5340@2|Bacteria,1U7YG@1239|Firmicutes,24AA3@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03076	411463.EUBVEN_00753	2.08e-218	605.0	COG2253@1|root,COG2253@2|Bacteria,1TQ54@1239|Firmicutes,24CDZ@186801|Clostridia	186801|Clostridia	V	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
NFNHFNFO_03077	33035.JPJF01000081_gene250	1.59e-38	130.0	2A2ID@1|root,30QVY@2|Bacteria,1V5QB@1239|Firmicutes,24KQU@186801|Clostridia,3Y1P5@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03078	33035.JPJF01000081_gene249	1.18e-164	461.0	COG1351@1|root,COG1351@2|Bacteria,1UHC2@1239|Firmicutes,25Q2G@186801|Clostridia,3XYYR@572511|Blautia	186801|Clostridia	F	Thymidylate synthase complementing protein	-	-	-	-	-	-	-	-	-	-	-	-	Thy1
NFNHFNFO_03079	33035.JPJF01000081_gene248	2.52e-93	272.0	COG0756@1|root,COG0756@2|Bacteria,1VGM6@1239|Firmicutes,24G06@186801|Clostridia,3Y1K3@572511|Blautia	186801|Clostridia	F	dUTPase	-	-	-	-	-	-	-	-	-	-	-	-	dUTPase
NFNHFNFO_03080	1235792.C808_02114	5.59e-61	188.0	COG1476@1|root,COG1476@2|Bacteria,1V789@1239|Firmicutes,24IXV@186801|Clostridia,27PGE@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19
NFNHFNFO_03081	33035.JPJF01000014_gene4901	2.49e-105	305.0	COG4474@1|root,COG4474@2|Bacteria,1TT4U@1239|Firmicutes,24EPT@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1273)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1273
NFNHFNFO_03082	742740.HMPREF9474_02129	3.16e-102	296.0	COG0346@1|root,COG0346@2|Bacteria,1V1Y9@1239|Firmicutes,24FQQ@186801|Clostridia,21ZBY@1506553|Lachnoclostridium	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Glyoxalase_2
NFNHFNFO_03083	138119.DSY1578	1.52e-136	393.0	COG1266@1|root,COG1266@2|Bacteria,1UFRU@1239|Firmicutes,24B41@186801|Clostridia	186801|Clostridia	S	CAAX protease self-immunity	-	-	-	ko:K07052	-	-	-	-	ko00000	-	-	-	Abi
NFNHFNFO_03084	1235798.C817_03906	1.89e-73	220.0	2DMZP@1|root,32UMQ@2|Bacteria,1VHU7@1239|Firmicutes,24QKJ@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
NFNHFNFO_03085	537013.CLOSTMETH_02182	1.48e-100	294.0	2DRB4@1|root,33B1T@2|Bacteria,1VQCB@1239|Firmicutes,24X99@186801|Clostridia	186801|Clostridia	S	YcxB-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YcxB
NFNHFNFO_03086	1235793.C809_04700	1.63e-07	50.1	28NW8@1|root,2ZBAZ@2|Bacteria,1UZDC@1239|Firmicutes,24BCZ@186801|Clostridia,27NP1@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Pfam:Pyridox_oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Putative_PNPOx
NFNHFNFO_03087	1235798.C817_03894	1.12e-116	335.0	28MX3@1|root,2ZB49@2|Bacteria,1TT80@1239|Firmicutes,24GAR@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3795)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3795
NFNHFNFO_03088	1235798.C817_00538	2.87e-23	88.6	2EBXV@1|root,335X7@2|Bacteria,1VIWB@1239|Firmicutes,24V0H@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3789)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3789
NFNHFNFO_03089	658086.HMPREF0994_00032	1.57e-63	211.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia,27INQ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DNA topoisomerase	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
NFNHFNFO_03090	1235800.C819_02618	1.23e-127	364.0	2EZDY@1|root,33SJ5@2|Bacteria,1VU22@1239|Firmicutes,24Z1I@186801|Clostridia,27JDE@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative tranposon-transfer assisting protein	-	-	-	-	-	-	-	-	-	-	-	-	TTRAP
NFNHFNFO_03091	1235799.C818_03906	3.07e-53	167.0	2EJBF@1|root,33D2K@2|Bacteria,1VKPI@1239|Firmicutes,24QTY@186801|Clostridia,27N5S@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03092	397288.C806_03611	7.76e-109	314.0	COG3265@1|root,COG3265@2|Bacteria,1UJWY@1239|Firmicutes,25FCU@186801|Clostridia,27M5S@186928|unclassified Lachnospiraceae	186801|Clostridia	G	gluconokinase activity	-	-	-	-	-	-	-	-	-	-	-	-	AAA_33
NFNHFNFO_03093	397288.C806_03610	4.5e-200	555.0	2DB8K@1|root,2Z7S1@2|Bacteria,1TRA1@1239|Firmicutes,24886@186801|Clostridia,27K90@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Streptomycin adenylyltransferase	-	-	-	ko:K05593	-	-	-	-	ko00000,ko01000,ko01504	-	-	-	Adenyl_transf
NFNHFNFO_03094	1235800.C819_02622	1.53e-60	187.0	2CHFE@1|root,32654@2|Bacteria,1US45@1239|Firmicutes,25A2I@186801|Clostridia,27PJT@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03095	1235800.C819_02623	1.86e-64	197.0	2BBYI@1|root,325H2@2|Bacteria,1URII@1239|Firmicutes,259EG@186801|Clostridia,27NH6@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03096	397288.C806_03705	0.0	967.0	COG1196@1|root,COG1196@2|Bacteria,1UJX2@1239|Firmicutes,25FCX@186801|Clostridia,27UDJ@186928|unclassified Lachnospiraceae	186801|Clostridia	D	MobA/MobL family	-	-	-	-	-	-	-	-	-	-	-	-	MobA_MobL
NFNHFNFO_03097	1469948.JPNB01000001_gene2052	7.33e-38	135.0	COG0500@1|root,COG2226@2|Bacteria,1UWA7@1239|Firmicutes,24WBZ@186801|Clostridia	186801|Clostridia	Q	Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT)	-	-	2.1.1.163,2.1.1.201	ko:K03183	ko00130,ko01100,ko01110,map00130,map01100,map01110	M00116,M00117	R04990,R04993,R06859,R08774,R09736	RC00003,RC01253,RC01662	ko00000,ko00001,ko00002,ko01000	-	-	-	Methyltransf_25
NFNHFNFO_03098	1235793.C809_00153	4.51e-30	106.0	2C2BP@1|root,347Z4@2|Bacteria,1VZ3U@1239|Firmicutes,252VT@186801|Clostridia,27PYW@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03099	397288.C806_03708	0.0	1057.0	COG1961@1|root,COG1961@2|Bacteria,1TPA6@1239|Firmicutes,247KF@186801|Clostridia,27KMV@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Domain of unknown function (DUF4368)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4368,Recombinase,Resolvase,Zn_ribbon_recom
NFNHFNFO_03100	478749.BRYFOR_06516	0.0	1075.0	COG0550@1|root,COG0550@2|Bacteria,1TPJD@1239|Firmicutes,24810@186801|Clostridia	186801|Clostridia	L	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone	-	-	5.99.1.2	ko:K03169	-	-	-	-	ko00000,ko01000,ko03032	-	-	-	Topoisom_bac,Toprim,Toprim_Crpt
NFNHFNFO_03101	397288.C806_04307	2.07e-79	236.0	2CCVN@1|root,31IBG@2|Bacteria,1V681@1239|Firmicutes,24IXK@186801|Clostridia,27P13@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Cysteine-rich VLP	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_VLP
NFNHFNFO_03102	1235798.C817_01085	4.83e-234	653.0	COG1961@1|root,COG1961@2|Bacteria,1TSXI@1239|Firmicutes,248RE@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NFNHFNFO_03103	1235798.C817_05572	1.7e-147	421.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,27VCY@189330|Dorea	186801|Clostridia	L	Arm DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NFNHFNFO_03104	1234679.BN424_3385	8.45e-37	143.0	28ZQY@1|root,2ZMFW@2|Bacteria,1V8GY@1239|Firmicutes,4HSMF@91061|Bacilli	91061|Bacilli	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03105	1232452.BAIB02000005_gene667	9.01e-99	290.0	2EBHH@1|root,335I0@2|Bacteria,1VGME@1239|Firmicutes,24TIT@186801|Clostridia	186801|Clostridia	S	YARHG domain	-	-	-	-	-	-	-	-	-	-	-	-	YARHG
NFNHFNFO_03110	397291.C804_04927	1.42e-134	387.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia	186801|Clostridia	L	resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NFNHFNFO_03111	1378168.N510_01583	5.67e-19	86.3	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes	1239|Firmicutes	L	resolvase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NFNHFNFO_03114	33035.JPJF01000120_gene1807	1.27e-31	112.0	2EDTM@1|root,30GQ5@2|Bacteria,1UGEW@1239|Firmicutes,25NV2@186801|Clostridia,3Y22M@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4177)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4177
NFNHFNFO_03115	33035.JPJF01000120_gene1806	3.87e-37	125.0	2FA0G@1|root,3429J@2|Bacteria,1VXK8@1239|Firmicutes,24RRN@186801|Clostridia,3Y0WK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03116	33035.JPJF01000029_gene2128	2.15e-310	848.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,248UK@186801|Clostridia	186801|Clostridia	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
NFNHFNFO_03117	33035.JPJF01000029_gene2127	8.6e-297	815.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,2492H@186801|Clostridia,3XZGT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
NFNHFNFO_03118	33035.JPJF01000029_gene2126	3.42e-297	813.0	COG4565@1|root,COG4565@2|Bacteria,1V2PC@1239|Firmicutes,24GSU@186801|Clostridia	186801|Clostridia	KT	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03119	33035.JPJF01000029_gene2125	4.15e-172	480.0	COG3442@1|root,COG3442@2|Bacteria,1U7I9@1239|Firmicutes,24A80@186801|Clostridia,3XZ8X@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07009	-	-	-	-	ko00000	-	-	-	GATase_3
NFNHFNFO_03120	33035.JPJF01000029_gene2124	3.04e-314	857.0	COG0771@1|root,COG0771@2|Bacteria,1UHPI@1239|Firmicutes,25E9J@186801|Clostridia,3XZ9H@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	murE2	-	6.3.2.13	ko:K01928	ko00300,ko00550,map00300,map00550	-	R02788	RC00064,RC00090	ko00000,ko00001,ko01000,ko01011	-	-	-	DUF1727,Mur_ligase_M
NFNHFNFO_03122	996306.SSUR61_0249	6.96e-27	99.4	COG3655@1|root,COG3655@2|Bacteria,1U9A3@1239|Firmicutes,4IJCS@91061|Bacilli,1WU3T@1307|Streptococcus suis	91061|Bacilli	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26
NFNHFNFO_03123	33035.JPJF01000029_gene2122	8.39e-210	582.0	COG0472@1|root,COG0472@2|Bacteria,1TP8W@1239|Firmicutes,247S7@186801|Clostridia	186801|Clostridia	M	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan	mraY	-	2.7.8.13	ko:K01000	ko00550,ko01100,ko01502,map00550,map01100,map01502	-	R05629,R05630	RC00002,RC02753	ko00000,ko00001,ko01000,ko01011	9.B.146	-	-	Glycos_transf_4,MraY_sig1
NFNHFNFO_03124	33035.JPJF01000029_gene2121	7.88e-34	116.0	2EHYT@1|root,33BQ9@2|Bacteria,1VM0T@1239|Firmicutes,24TTI@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03125	33035.JPJF01000029_gene2120	4.35e-23	88.2	2BB2A@1|root,324IE@2|Bacteria,1UQTB@1239|Firmicutes,24UV2@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03126	33035.JPJF01000029_gene2119	0.0	971.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3XYNG@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NFNHFNFO_03127	33035.JPJF01000029_gene2118	3.15e-120	345.0	COG1954@1|root,COG1954@2|Bacteria,1V4IE@1239|Firmicutes,24HDM@186801|Clostridia,3Y03V@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	glpP	-	-	ko:K02443	-	-	-	-	ko00000,ko03000	-	-	-	G3P_antiterm
NFNHFNFO_03128	33035.JPJF01000029_gene2117	0.0	889.0	COG0579@1|root,COG0579@2|Bacteria,1TRDH@1239|Firmicutes,248IK@186801|Clostridia,3XZGX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	lhgO	-	1.1.5.3	ko:K00111	ko00564,ko01110,map00564,map01110	-	R00848	RC00029	ko00000,ko00001,ko01000	-	-	-	DAO,Fer2_BFD
NFNHFNFO_03129	33035.JPJF01000029_gene2116	1.05e-291	798.0	COG0446@1|root,COG0446@2|Bacteria,1TQH5@1239|Firmicutes,247YR@186801|Clostridia,3XYIW@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Pyr_redox_2,Pyr_redox_3
NFNHFNFO_03130	33035.JPJF01000029_gene2115	1.3e-72	219.0	COG3862@1|root,COG3862@2|Bacteria,1VA4U@1239|Firmicutes,24MN9@186801|Clostridia,3Y0DY@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1667)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1667
NFNHFNFO_03131	33035.JPJF01000029_gene2114	5.02e-190	528.0	COG0647@1|root,COG0647@2|Bacteria,1TQGM@1239|Firmicutes,24B6W@186801|Clostridia,3Y1BJ@572511|Blautia	186801|Clostridia	G	Haloacid dehalogenase-like hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_6,Hydrolase_like,NUDIX
NFNHFNFO_03132	33035.JPJF01000029_gene2113	1.37e-150	424.0	COG1489@1|root,COG1489@2|Bacteria,1VTYF@1239|Firmicutes,25E56@186801|Clostridia,3XZS7@572511|Blautia	186801|Clostridia	S	Sugar fermentation stimulation protein	sfsA	-	-	ko:K06206	-	-	-	-	ko00000	-	-	-	SfsA
NFNHFNFO_03133	33035.JPJF01000029_gene2112	4.41e-229	633.0	COG1194@1|root,COG1194@2|Bacteria,1TPUT@1239|Firmicutes,25E4K@186801|Clostridia,3XZJ1@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	mutY	-	-	ko:K03575	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	EndIII_4Fe-2S,HhH-GPD,NUDIX_4,SfsA
NFNHFNFO_03134	33035.JPJF01000029_gene2111	3.49e-232	639.0	COG0463@1|root,COG0463@2|Bacteria,1TT6C@1239|Firmicutes,248F2@186801|Clostridia,3XYRU@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	kfoC_2	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NFNHFNFO_03135	33035.JPJF01000029_gene2110	6.7e-148	417.0	COG0671@1|root,COG0671@2|Bacteria,1V2ZH@1239|Firmicutes,24HRY@186801|Clostridia,3Y0B6@572511|Blautia	186801|Clostridia	I	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	PAP2,PAP2_3
NFNHFNFO_03136	33035.JPJF01000029_gene2109	9.79e-194	538.0	COG0584@1|root,COG0584@2|Bacteria,1V1PF@1239|Firmicutes,24EG1@186801|Clostridia,3Y04X@572511|Blautia	186801|Clostridia	C	Glycerophosphoryl diester phosphodiesterase family	-	-	-	-	-	-	-	-	-	-	-	-	GDPD
NFNHFNFO_03137	33035.JPJF01000029_gene2108	5.2e-208	577.0	COG1597@1|root,COG1597@2|Bacteria,1TQJH@1239|Firmicutes,24BHT@186801|Clostridia,3XZTC@572511|Blautia	186801|Clostridia	I	COG COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase	ytlR	-	-	-	-	-	-	-	-	-	-	-	DAGK_cat
NFNHFNFO_03138	33035.JPJF01000029_gene2107	3.55e-109	314.0	COG1803@1|root,COG1803@2|Bacteria,1V58X@1239|Firmicutes,24J2X@186801|Clostridia,3Y2C5@572511|Blautia	186801|Clostridia	G	MGS-like domain	-	-	4.2.3.3	ko:K01734	ko00640,ko01120,map00640,map01120	-	R01016	RC00424	ko00000,ko00001,ko01000	-	-	-	MGS
NFNHFNFO_03139	33035.JPJF01000029_gene2106	9.33e-178	496.0	COG0860@1|root,COG0860@2|Bacteria,1TS91@1239|Firmicutes,25B1N@186801|Clostridia,3XZHM@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	cwlC	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3,SPOR
NFNHFNFO_03140	33035.JPJF01000029_gene2105	1.33e-294	807.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3Y0XB@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_03141	33035.JPJF01000029_gene2104	9.04e-137	388.0	29WCQ@1|root,30HYD@2|Bacteria,1TXD7@1239|Firmicutes,25JJX@186801|Clostridia,3Y1HX@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03142	33035.JPJF01000029_gene2103	2.73e-156	439.0	COG2357@1|root,COG2357@2|Bacteria,1TQ2F@1239|Firmicutes,249FE@186801|Clostridia,3XZ07@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NFNHFNFO_03143	33035.JPJF01000029_gene2102	7.4e-195	541.0	2CC4I@1|root,2Z8PZ@2|Bacteria,1TQTT@1239|Firmicutes,24AJ3@186801|Clostridia,3XZ5E@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03144	537007.BLAHAN_05046	1.89e-119	345.0	COG0484@1|root,COG0484@2|Bacteria,1V1GK@1239|Firmicutes,2494E@186801|Clostridia,3XZYJ@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	ko:K03686	-	-	-	-	ko00000,ko03029,ko03110	-	-	-	DnaJ,TPR_2
NFNHFNFO_03145	33035.JPJF01000102_gene3395	3.89e-106	308.0	2DQ8Z@1|root,335CG@2|Bacteria,1V9R5@1239|Firmicutes,24I50@186801|Clostridia,3Y02P@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03146	33035.JPJF01000102_gene3396	3.38e-292	799.0	COG3681@1|root,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,3XYV4@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
NFNHFNFO_03147	33035.JPJF01000102_gene3397	4.79e-196	545.0	COG4399@1|root,COG4399@2|Bacteria,1TQDH@1239|Firmicutes,24K94@186801|Clostridia,3Y1DQ@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF445)	-	-	-	-	-	-	-	-	-	-	-	-	DUF445
NFNHFNFO_03148	1158612.I580_02404	5.92e-83	288.0	COG3664@1|root,COG4977@1|root,COG3664@2|Bacteria,COG4977@2|Bacteria,1TQGI@1239|Firmicutes,4I6Q0@91061|Bacilli,4B1FD@81852|Enterococcaceae	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_39,HTH_18
NFNHFNFO_03149	911239.CF149_13190	2.96e-38	143.0	COG2843@1|root,COG2843@2|Bacteria,1N8I2@1224|Proteobacteria,1SEGB@1236|Gammaproteobacteria	1236|Gammaproteobacteria	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
NFNHFNFO_03150	1230342.CTM_23689	7.97e-221	623.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,2492H@186801|Clostridia,36EX4@31979|Clostridiaceae	186801|Clostridia	S	amidohydrolase	abgB	-	-	ko:K12941	-	-	-	-	ko00000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NFNHFNFO_03151	556261.HMPREF0240_03525	3e-77	240.0	arCOG13338@1|root,32UAU@2|Bacteria,1VBA1@1239|Firmicutes,24P3H@186801|Clostridia,36MUA@31979|Clostridiaceae	186801|Clostridia	S	Domain of unknown function (DUF5058)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5058
NFNHFNFO_03152	556261.HMPREF0240_03526	1.42e-90	273.0	28N4D@1|root,2ZB9V@2|Bacteria,1UPRR@1239|Firmicutes,24MJV@186801|Clostridia,36S3K@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03153	33035.JPJF01000102_gene3398	1.28e-147	416.0	COG2964@1|root,COG2964@2|Bacteria,1V33R@1239|Firmicutes,25CHI@186801|Clostridia,3Y1I2@572511|Blautia	186801|Clostridia	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
NFNHFNFO_03154	33035.JPJF01000102_gene3399	7.58e-77	229.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3Y05K@572511|Blautia	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
NFNHFNFO_03155	33035.JPJF01000102_gene3400	7.37e-226	623.0	COG2515@1|root,COG2515@2|Bacteria,1V07K@1239|Firmicutes,258XR@186801|Clostridia,3Y21E@572511|Blautia	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	-	-	-	-	-	-	-	-	-	-	-	-	PALP
NFNHFNFO_03156	33035.JPJF01000102_gene3401	0.0	880.0	COG1757@1|root,COG1757@2|Bacteria,1TP8A@1239|Firmicutes,247V4@186801|Clostridia,3XYNQ@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
NFNHFNFO_03157	33035.JPJF01000102_gene3402	1.15e-83	248.0	2CEH6@1|root,32RZW@2|Bacteria,1UGH5@1239|Firmicutes,24KBE@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Polyketide_cyc2
NFNHFNFO_03158	1410617.JHXH01000017_gene1122	3.21e-44	150.0	COG0454@1|root,COG0456@2|Bacteria,1VRI3@1239|Firmicutes,25H3M@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_03159	318464.IO99_06650	7.73e-96	288.0	COG3393@1|root,COG3393@2|Bacteria,1TRN7@1239|Firmicutes,24A2B@186801|Clostridia,36HV9@31979|Clostridiaceae	186801|Clostridia	S	GNAT acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,GNAT_acetyltran
NFNHFNFO_03160	33035.JPJF01000102_gene3405	1.38e-87	262.0	29UTS@1|root,30G67@2|Bacteria,1V4QI@1239|Firmicutes,24G9Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03161	33035.JPJF01000102_gene3407	1.94e-110	320.0	COG1670@1|root,COG1670@2|Bacteria,1V2EM@1239|Firmicutes,24GSX@186801|Clostridia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
NFNHFNFO_03162	33035.JPJF01000102_gene3408	0.0	898.0	COG2508@1|root,COG2508@2|Bacteria,1TRRH@1239|Firmicutes	1239|Firmicutes	QT	COG2508 Regulator of polyketide synthase expression	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NFNHFNFO_03163	33035.JPJF01000102_gene3409	5.76e-247	677.0	COG0407@1|root,COG0407@2|Bacteria,1V7V8@1239|Firmicutes,24M1I@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
NFNHFNFO_03164	553973.CLOHYLEM_07142	1.28e-81	248.0	COG1309@1|root,COG1309@2|Bacteria,1VGTE@1239|Firmicutes,24Q9W@186801|Clostridia,21ZVM@1506553|Lachnoclostridium	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_03165	553973.CLOHYLEM_07140	4.99e-117	340.0	COG1136@1|root,COG1136@2|Bacteria,1TQC9@1239|Firmicutes,248Z6@186801|Clostridia,21Z5W@1506553|Lachnoclostridium	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_03166	553973.CLOHYLEM_07139	0.0	918.0	COG0577@1|root,COG0577@2|Bacteria,1TPHU@1239|Firmicutes,248RV@186801|Clostridia,21YHB@1506553|Lachnoclostridium	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NFNHFNFO_03167	33035.JPJF01000102_gene3410	3.45e-105	306.0	2B4B6@1|root,30XHG@2|Bacteria,1V4KI@1239|Firmicutes,25D1M@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03168	33035.JPJF01000102_gene3411	6.12e-161	455.0	28I08@1|root,2ZBVK@2|Bacteria,1V2VU@1239|Firmicutes,25DBA@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03169	33035.JPJF01000102_gene3412	2.56e-237	661.0	29WCX@1|root,30HYK@2|Bacteria,1UDXU@1239|Firmicutes,25IS5@186801|Clostridia,3Y24Z@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03171	33035.JPJF01000102_gene3414	3.41e-111	323.0	COG1247@1|root,COG1247@2|Bacteria,1V6X5@1239|Firmicutes,24IB5@186801|Clostridia,3Y0B0@572511|Blautia	186801|Clostridia	M	Acetyltransferase (GNAT) domain	pat	-	2.3.1.183	ko:K03823	ko00440,ko01130,map00440,map01130	-	R08871,R08938	RC00004,RC00064	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_4
NFNHFNFO_03172	33035.JPJF01000102_gene3417	8.61e-102	296.0	COG0454@1|root,COG0456@2|Bacteria,1VGZX@1239|Firmicutes,24I40@186801|Clostridia,3Y0HB@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_03173	33035.JPJF01000102_gene3418	1.81e-299	823.0	COG1767@1|root,COG3697@1|root,COG1767@2|Bacteria,COG3697@2|Bacteria,1TQGQ@1239|Firmicutes,24BQH@186801|Clostridia,3Y13R@572511|Blautia	186801|Clostridia	HI	ATP:dephospho-CoA triphosphoribosyl transferase	citG	-	2.4.2.52,2.7.7.61	ko:K05966,ko:K13927	ko02020,map02020	-	R09675,R10706	RC00049,RC00063	ko00000,ko00001,ko01000	-	-	-	CitG,CitX
NFNHFNFO_03174	33035.JPJF01000102_gene3419	1.23e-218	607.0	COG3053@1|root,COG3053@2|Bacteria,1TSGQ@1239|Firmicutes,248Y4@186801|Clostridia,3Y12J@572511|Blautia	186801|Clostridia	C	Citrate lyase ligase C-terminal domain	citC	-	6.2.1.22	ko:K01910	ko02020,map02020	-	R04449	RC00012,RC00039	ko00000,ko00001,ko01000	-	-	-	Acetyltransf_1,Acetyltransf_10,Citrate_ly_lig
NFNHFNFO_03175	33035.JPJF01000102_gene3420	6.51e-107	309.0	COG2080@1|root,COG2080@2|Bacteria,1V6HE@1239|Firmicutes,24J9B@186801|Clostridia,3Y2B4@572511|Blautia	186801|Clostridia	C	[2Fe-2S] binding domain	cutS	-	1.17.1.5,1.2.5.3	ko:K03518,ko:K20446	ko00760,ko01120,map00760,map01120	-	R01720,R11168	RC00589,RC02800	ko00000,ko00001,ko01000	-	-	-	Fer2,Fer2_2
NFNHFNFO_03176	33035.JPJF01000102_gene3421	2.9e-178	499.0	COG1319@1|root,COG1319@2|Bacteria,1V3PV@1239|Firmicutes,24HB7@186801|Clostridia	186801|Clostridia	C	FAD binding domain in molybdopterin dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	CO_deh_flav_C,FAD_binding_5
NFNHFNFO_03177	33035.JPJF01000102_gene3422	0.0	1395.0	COG1529@1|root,COG1529@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia	186801|Clostridia	C	aldehyde oxidase and xanthine dehydrogenase, a b hammerhead	-	-	1.17.1.4	ko:K00087	ko00230,ko01100,ko01120,map00230,map01100,map01120	M00546	R01768,R02103	RC00143	ko00000,ko00001,ko00002,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2
NFNHFNFO_03178	33035.JPJF01000102_gene3423	0.0	953.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,24A4G@186801|Clostridia	186801|Clostridia	E	Aromatic amino acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Lyase_aromatic
NFNHFNFO_03179	742740.HMPREF9474_01501	0.0	931.0	COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,2482K@186801|Clostridia,21Z3Y@1506553|Lachnoclostridium	186801|Clostridia	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	ko:K05020	-	-	-	-	ko00000,ko02000	2.A.15.1.1,2.A.15.1.11	-	-	BCCT
NFNHFNFO_03180	33035.JPJF01000110_gene5205	1.16e-63	195.0	2ED91@1|root,3375H@2|Bacteria,1VFTX@1239|Firmicutes,24RJH@186801|Clostridia,3Y1TN@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03181	33035.JPJF01000110_gene5204	2e-129	368.0	COG3758@1|root,COG3758@2|Bacteria,1VH52@1239|Firmicutes,24P8J@186801|Clostridia,3Y1PF@572511|Blautia	186801|Clostridia	S	HutD	-	-	-	-	-	-	-	-	-	-	-	-	HutD
NFNHFNFO_03182	33035.JPJF01000110_gene5203	0.0	1832.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1TR6V@1239|Firmicutes,24AA2@186801|Clostridia	186801|Clostridia	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
NFNHFNFO_03183	592026.GCWU0000282_002968	8.32e-174	501.0	COG1653@1|root,COG1653@2|Bacteria,1UYBV@1239|Firmicutes,24E6F@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03184	742733.HMPREF9469_05466	1.06e-150	430.0	COG1175@1|root,COG1175@2|Bacteria,1TRI2@1239|Firmicutes,24DZ7@186801|Clostridia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_03185	1121115.AXVN01000108_gene626	3.75e-132	382.0	COG0395@1|root,COG0395@2|Bacteria,1UXJD@1239|Firmicutes,25M52@186801|Clostridia,3Y1KD@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_03186	1437610.BREU_2246	6.91e-284	783.0	COG1621@1|root,COG1621@2|Bacteria,2H3S0@201174|Actinobacteria,4D05M@85004|Bifidobacteriales	201174|Actinobacteria	G	Glycosyl hydrolases family 32	-	-	3.2.1.26	ko:K01193	ko00052,ko00500,ko01100,map00052,map00500,map01100	-	R00801,R00802,R02410,R03635,R03921,R06088	RC00028,RC00077	ko00000,ko00001,ko01000	-	GH32	-	Glyco_hydro_32C,Glyco_hydro_32N
NFNHFNFO_03187	33035.JPJF01000015_gene4962	3.29e-158	448.0	COG5464@1|root,COG5464@2|Bacteria,1V394@1239|Firmicutes,24GXK@186801|Clostridia,3Y2CV@572511|Blautia	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NFNHFNFO_03188	33035.JPJF01000015_gene4961	7.47e-88	258.0	COG0346@1|root,COG0346@2|Bacteria,1V7XP@1239|Firmicutes,24KYI@186801|Clostridia,3Y0HK@572511|Blautia	186801|Clostridia	E	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily	-	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase,Glyoxalase_4
NFNHFNFO_03189	33035.JPJF01000015_gene4960	7.24e-244	671.0	COG0673@1|root,COG0673@2|Bacteria,1UGN1@1239|Firmicutes,249ZU@186801|Clostridia,3Y1K5@572511|Blautia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NFNHFNFO_03190	33035.JPJF01000015_gene4959	8.06e-236	650.0	COG0275@1|root,COG0275@2|Bacteria,1TP5R@1239|Firmicutes,248PH@186801|Clostridia,3XZ5Z@572511|Blautia	186801|Clostridia	H	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA	rsmH2	-	2.1.1.199	ko:K03438	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltransf_5
NFNHFNFO_03191	33035.JPJF01000015_gene4958	7.46e-167	470.0	COG1408@1|root,COG1408@2|Bacteria,1UU17@1239|Firmicutes,25CIK@186801|Clostridia	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NFNHFNFO_03192	33035.JPJF01000015_gene4955	1.02e-131	375.0	COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,249KF@186801|Clostridia,3XZYR@572511|Blautia	186801|Clostridia	S	Maltose acetyltransferase	-	-	2.3.1.79	ko:K00661	-	-	-	-	ko00000,ko01000	-	-	-	Hexapep,Hexapep_2,Mac
NFNHFNFO_03193	33035.JPJF01000015_gene4954	0.0	1018.0	COG1640@1|root,COG1640@2|Bacteria,1W5VQ@1239|Firmicutes,25E46@186801|Clostridia,3XYYI@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	malQ_1	-	2.4.1.25	ko:K00705	ko00500,ko01100,map00500,map01100	-	R05196	RC00049	ko00000,ko00001,ko01000	-	GH77	-	Glyco_hydro_77
NFNHFNFO_03194	33035.JPJF01000015_gene4953	0.0	1118.0	COG0366@1|root,COG0366@2|Bacteria,1TP53@1239|Firmicutes,247XR@186801|Clostridia,3XYJJ@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	-	-	3.2.1.1,3.2.1.10	ko:K01176,ko:K01182	ko00052,ko00500,ko01100,ko04973,map00052,map00500,map01100,map04973	-	R00801,R01718,R01791,R02108,R02112,R06199,R11262	RC00028,RC00059,RC00077,RC00451	ko00000,ko00001,ko01000	-	GH13	-	Alpha-amylase,DUF3459,Malt_amylase_C
NFNHFNFO_03195	33035.JPJF01000015_gene4952	2.26e-215	595.0	COG2207@1|root,COG2207@2|Bacteria,1U657@1239|Firmicutes,247V5@186801|Clostridia,3XZWM@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_03196	33035.JPJF01000015_gene4950	0.0	1625.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3XZIP@572511|Blautia	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NFNHFNFO_03198	33035.JPJF01000015_gene4949	8.8e-211	592.0	2BBU1@1|root,325CB@2|Bacteria,1V80P@1239|Firmicutes,24IWW@186801|Clostridia,3Y0VX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03199	33035.JPJF01000015_gene4948	1.76e-171	481.0	COG4509@1|root,COG4509@2|Bacteria,1V2FT@1239|Firmicutes,24GN2@186801|Clostridia,3XZ9S@572511|Blautia	186801|Clostridia	S	Sortase family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NFNHFNFO_03200	33035.JPJF01000015_gene4947	1.68e-167	468.0	COG0846@1|root,COG0846@2|Bacteria,1TQKD@1239|Firmicutes,2491J@186801|Clostridia,3XZIR@572511|Blautia	186801|Clostridia	K	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form	cobB	-	-	ko:K12410	-	-	-	-	ko00000,ko01000	-	-	-	SIR2
NFNHFNFO_03201	33035.JPJF01000015_gene4946	1.53e-39	130.0	COG4481@1|root,COG4481@2|Bacteria,1VEQ7@1239|Firmicutes,24QKA@186801|Clostridia,3Y0KE@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF951
NFNHFNFO_03202	33035.JPJF01000015_gene4945	1.01e-61	189.0	COG0360@1|root,COG0360@2|Bacteria,1VA18@1239|Firmicutes,24QZQ@186801|Clostridia,3Y068@572511|Blautia	186801|Clostridia	J	Binds together with S18 to 16S ribosomal RNA	rpsF	-	-	ko:K02990	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011,ko03029	-	-	-	Ribosomal_S6
NFNHFNFO_03203	33035.JPJF01000015_gene4944	7.09e-100	290.0	COG0629@1|root,COG0629@2|Bacteria,1V3WT@1239|Firmicutes,24HF9@186801|Clostridia,3XZWB@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ssb	-	-	ko:K03111	ko03030,ko03430,ko03440,map03030,map03430,map03440	-	-	-	ko00000,ko00001,ko03029,ko03032,ko03400	-	-	-	SSB
NFNHFNFO_03204	33035.JPJF01000015_gene4943	4.33e-57	177.0	COG0238@1|root,COG0238@2|Bacteria,1V9XS@1239|Firmicutes,24MQV@186801|Clostridia,3Y0A3@572511|Blautia	186801|Clostridia	J	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit	rpsR	-	-	ko:K02963	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S18
NFNHFNFO_03205	33035.JPJF01000015_gene4942	3e-157	442.0	COG0745@1|root,COG0745@2|Bacteria,1TRS2@1239|Firmicutes,24AF1@186801|Clostridia	186801|Clostridia	T	COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_03206	33035.JPJF01000015_gene4941	0.0	934.0	COG0642@1|root,COG2205@2|Bacteria,1V2VP@1239|Firmicutes,25E8Z@186801|Clostridia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NFNHFNFO_03207	33035.JPJF01000015_gene4940	0.0	1277.0	COG3887@1|root,COG3887@2|Bacteria,1TPGP@1239|Firmicutes,2484R@186801|Clostridia,3XYI8@572511|Blautia	186801|Clostridia	T	signaling protein consisting of a modified GGDEF domain and a DHH domain	yybT	-	-	-	-	-	-	-	-	-	-	-	DHH,DHHA1
NFNHFNFO_03208	33035.JPJF01000015_gene4939	7.84e-91	267.0	COG0359@1|root,COG0359@2|Bacteria,1V6QG@1239|Firmicutes,24MT6@186801|Clostridia,3XZYF@572511|Blautia	186801|Clostridia	J	Binds to the 23S rRNA	rplI	-	-	ko:K02939	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L9_C,Ribosomal_L9_N
NFNHFNFO_03209	33035.JPJF01000015_gene4938	1.13e-305	835.0	COG0305@1|root,COG0305@2|Bacteria,1TPCT@1239|Firmicutes,247W3@186801|Clostridia,3XYP7@572511|Blautia	186801|Clostridia	L	Participates in initiation and elongation during chromosome replication	dnaB	-	3.6.4.12	ko:K02314	ko03030,ko04112,map03030,map04112	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	DnaB,DnaB_C
NFNHFNFO_03210	33035.JPJF01000015_gene4937	9.4e-103	302.0	28P2J@1|root,2ZBYK@2|Bacteria,1V6UQ@1239|Firmicutes,249N5@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF3796)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3796
NFNHFNFO_03211	33035.JPJF01000015_gene4936	1.19e-37	126.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QJ1@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NFNHFNFO_03212	33035.JPJF01000015_gene4935	6.72e-63	193.0	2E34N@1|root,32Y4R@2|Bacteria,1VHXC@1239|Firmicutes,24U1R@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03213	33035.JPJF01000015_gene4934	2.17e-35	120.0	COG1476@1|root,COG1476@2|Bacteria,1VEM3@1239|Firmicutes,24QKH@186801|Clostridia	186801|Clostridia	K	PFAM Helix-turn-helix	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NFNHFNFO_03215	33035.JPJF01000015_gene4933	1.05e-232	642.0	COG2805@1|root,COG2805@2|Bacteria,1TQ5F@1239|Firmicutes,249H9@186801|Clostridia,3XYY6@572511|Blautia	186801|Clostridia	NU	Type II/IV secretion system protein	pilT	-	-	ko:K02669	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSE
NFNHFNFO_03216	33035.JPJF01000015_gene4932	1.31e-74	226.0	2EIJK@1|root,32Z23@2|Bacteria,1VG8I@1239|Firmicutes,24RPX@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03217	33035.JPJF01000015_gene4931	9.3e-64	198.0	29VBD@1|root,30GRK@2|Bacteria,1UGHN@1239|Firmicutes,25NZJ@186801|Clostridia,3Y0TT@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03218	33035.JPJF01000015_gene4930	3.31e-91	269.0	2CFUD@1|root,3038G@2|Bacteria,1TTUB@1239|Firmicutes,258DI@186801|Clostridia,3Y0QR@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4860)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4860
NFNHFNFO_03219	33035.JPJF01000015_gene4929	9.88e-52	164.0	2E4EX@1|root,2ZVEF@2|Bacteria,1W43C@1239|Firmicutes,2563F@186801|Clostridia,3Y0WS@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03220	33035.JPJF01000015_gene4928	5.41e-172	488.0	COG1459@1|root,COG1459@2|Bacteria,1TQRZ@1239|Firmicutes,249FV@186801|Clostridia,3XZX3@572511|Blautia	186801|Clostridia	NU	Type II secretion system (T2SS), protein F	gspF	-	-	ko:K02653	-	-	-	-	ko00000,ko02035,ko02044	3.A.15.2	-	-	T2SSF
NFNHFNFO_03221	33035.JPJF01000015_gene4927	2.14e-210	583.0	COG1305@1|root,COG1305@2|Bacteria,1TP7G@1239|Firmicutes,25KCQ@186801|Clostridia,3XYXN@572511|Blautia	186801|Clostridia	E	Transglutaminase-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NFNHFNFO_03222	33035.JPJF01000015_gene4926	1.38e-98	293.0	COG1555@1|root,COG1555@2|Bacteria,1VA3W@1239|Firmicutes,24MQF@186801|Clostridia,3Y08K@572511|Blautia	186801|Clostridia	L	Psort location CytoplasmicMembrane, score	comEA	-	-	ko:K02237	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	HHH_3,SLBB
NFNHFNFO_03223	33035.JPJF01000015_gene4925	2.3e-159	447.0	COG0745@1|root,COG0745@2|Bacteria,1TPQG@1239|Firmicutes,248Z4@186801|Clostridia,3XYMR@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_03224	33035.JPJF01000015_gene4924	0.0	897.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XYXC@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	2.7.13.3	ko:K02484	-	-	-	-	ko00000,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
NFNHFNFO_03225	33035.JPJF01000015_gene4923	3.75e-210	582.0	COG5401@1|root,COG5401@2|Bacteria,1UXYS@1239|Firmicutes,24EK4@186801|Clostridia,3Y07U@572511|Blautia	186801|Clostridia	S	Sporulation and spore germination	-	-	-	ko:K06298	-	-	-	-	ko00000	-	-	-	Germane
NFNHFNFO_03226	33035.JPJF01000015_gene4922	0.0	1165.0	COG0658@1|root,COG2333@1|root,COG0658@2|Bacteria,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3XZP4@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Competence,DUF4131,Lactamase_B
NFNHFNFO_03227	33035.JPJF01000015_gene4921	3.75e-220	608.0	COG1466@1|root,COG1466@2|Bacteria,1TRM0@1239|Firmicutes,24ASN@186801|Clostridia,3XZ4T@572511|Blautia	186801|Clostridia	L	DNA polymerase III, delta' subunit	holA	-	2.7.7.7	ko:K02340	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta
NFNHFNFO_03228	33035.JPJF01000015_gene4920	5.1e-43	141.0	COG0268@1|root,COG0268@2|Bacteria,1VEGX@1239|Firmicutes,24QNX@186801|Clostridia,3Y0DB@572511|Blautia	186801|Clostridia	J	Binds directly to 16S ribosomal RNA	rpsT	-	-	ko:K02968	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_S20p
NFNHFNFO_03229	33035.JPJF01000015_gene4919	4e-205	568.0	COG0680@1|root,COG0680@2|Bacteria,1TPFY@1239|Firmicutes,248TE@186801|Clostridia,3XYQQ@572511|Blautia	186801|Clostridia	C	Initiates the rapid degradation of small, acid-soluble proteins during spore germination	gpr	-	3.4.24.78	ko:K06012	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_A25
NFNHFNFO_03230	33035.JPJF01000015_gene4918	5.07e-250	693.0	COG0860@1|root,COG0860@2|Bacteria,1TSFS@1239|Firmicutes,2488U@186801|Clostridia,3XZD8@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	spoIIP	-	-	ko:K06385	-	-	-	-	ko00000	-	-	-	SpoIIP
NFNHFNFO_03231	33035.JPJF01000015_gene4917	0.0	1164.0	COG0481@1|root,COG0481@2|Bacteria,1TP0G@1239|Firmicutes,247V8@186801|Clostridia,3XYYN@572511|Blautia	186801|Clostridia	M	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner	lepA	-	-	ko:K03596	ko05134,map05134	-	-	-	ko00000,ko00001	-	-	-	EFG_C,GTP_EFTU,GTP_EFTU_D2,LepA_C
NFNHFNFO_03232	33035.JPJF01000067_gene3521	8.25e-249	686.0	COG0635@1|root,COG0635@2|Bacteria,1TPES@1239|Firmicutes,247P8@186801|Clostridia,3XYHD@572511|Blautia	186801|Clostridia	H	Involved in the biosynthesis of porphyrin-containing compound	hemN	-	-	-	-	-	-	-	-	-	-	-	HemN_C,Radical_SAM
NFNHFNFO_03233	33035.JPJF01000067_gene3522	4.21e-100	290.0	COG0517@1|root,COG0517@2|Bacteria,1V7XE@1239|Firmicutes,24HF5@186801|Clostridia,3Y07B@572511|Blautia	186801|Clostridia	S	COG COG0517 FOG CBS domain	-	-	-	-	-	-	-	-	-	-	-	-	CBS
NFNHFNFO_03235	33035.JPJF01000067_gene3525	0.0	1833.0	COG0178@1|root,COG0178@2|Bacteria,1TPIJ@1239|Firmicutes,2485F@186801|Clostridia,3XYNU@572511|Blautia	186801|Clostridia	L	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate	uvrA	-	-	ko:K03701	ko03420,map03420	-	-	-	ko00000,ko00001,ko03400	-	-	-	ABC_tran
NFNHFNFO_03236	33035.JPJF01000067_gene3526	3.77e-226	625.0	COG1077@1|root,COG1077@2|Bacteria,1TP51@1239|Firmicutes,247RG@186801|Clostridia,3XZC7@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score	mreB	-	-	ko:K03569	-	-	-	-	ko00000,ko02048,ko03036,ko04812	1.A.33.1,9.B.157.1	-	-	MreB_Mbl
NFNHFNFO_03237	33035.JPJF01000067_gene3527	0.0	1402.0	COG0507@1|root,COG0507@2|Bacteria,1TPZH@1239|Firmicutes,247R7@186801|Clostridia,3XYVD@572511|Blautia	186801|Clostridia	L	DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity	recD2	-	3.1.11.5	ko:K03581	ko03440,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	AAA_30,HHH_4,HHH_5,UvrD_C_2
NFNHFNFO_03238	33035.JPJF01000067_gene3528	6.83e-136	387.0	COG1040@1|root,COG1040@2|Bacteria,1VF2G@1239|Firmicutes,24IG6@186801|Clostridia,3Y06Y@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	comF	-	-	ko:K02242	-	M00429	-	-	ko00000,ko00002,ko02044	-	-	-	Pribosyltran
NFNHFNFO_03239	33035.JPJF01000067_gene3529	3e-88	260.0	2DIZ6@1|root,32UC0@2|Bacteria,1VGDB@1239|Firmicutes,24SFK@186801|Clostridia,3Y0CW@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03240	33035.JPJF01000067_gene3530	4.6e-216	600.0	28K89@1|root,2Z9W3@2|Bacteria,1V1PZ@1239|Firmicutes,24D2W@186801|Clostridia,3XZ3Y@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03241	33035.JPJF01000067_gene3531	1.02e-180	506.0	COG1624@1|root,COG1624@2|Bacteria,1TPRW@1239|Firmicutes,249K8@186801|Clostridia,3XZJU@572511|Blautia	186801|Clostridia	S	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria	dacA	-	2.7.7.85	ko:K18672	-	-	-	-	ko00000,ko01000	-	-	-	DisA_N
NFNHFNFO_03242	33035.JPJF01000067_gene3532	3.38e-227	636.0	COG4856@1|root,COG4856@2|Bacteria,1UZEV@1239|Firmicutes,25CGI@186801|Clostridia,3XYTZ@572511|Blautia	186801|Clostridia	S	YbbR-like protein	-	-	-	-	-	-	-	-	-	-	-	-	YbbR
NFNHFNFO_03243	33035.JPJF01000067_gene3533	1.15e-52	166.0	COG1925@1|root,COG1925@2|Bacteria,1VA23@1239|Firmicutes,24N32@186801|Clostridia,3Y0CN@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	-	ko:K11189	-	-	-	-	ko00000,ko02000	4.A.2.1	-	-	PTS-HPr
NFNHFNFO_03244	33035.JPJF01000067_gene3534	1.72e-152	430.0	COG1296@1|root,COG1296@2|Bacteria,1TSXD@1239|Firmicutes,24CRN@186801|Clostridia,3XZSK@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.99	ygaZ	-	-	-	-	-	-	-	-	-	-	-	AzlC
NFNHFNFO_03245	33035.JPJF01000067_gene3535	2.92e-57	178.0	COG4392@1|root,COG4392@2|Bacteria,1VAKN@1239|Firmicutes,24N0I@186801|Clostridia,3Y0E3@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	AzlD
NFNHFNFO_03246	33035.JPJF01000067_gene3536	1.98e-295	850.0	COG1376@1|root,COG5263@1|root,COG1376@2|Bacteria,COG5263@2|Bacteria,1UVCF@1239|Firmicutes,24BKI@186801|Clostridia,3XZR4@572511|Blautia	186801|Clostridia	S	L,D-transpeptidase catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,YkuD
NFNHFNFO_03247	1121333.JMLH01000011_gene670	0.0	1245.0	COG4932@1|root,COG4932@2|Bacteria,1TS9Q@1239|Firmicutes,3VPKA@526524|Erysipelotrichia	526524|Erysipelotrichia	M	Psort location Cellwall, score	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
NFNHFNFO_03248	33035.JPJF01000089_gene115	1.01e-71	220.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3XYV6@572511|Blautia	186801|Clostridia	T	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_03249	33035.JPJF01000089_gene115	2.29e-51	167.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3XYV6@572511|Blautia	186801|Clostridia	T	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_03250	33035.JPJF01000089_gene114	0.0	1247.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_03251	33035.JPJF01000089_gene113	3.08e-216	598.0	COG0039@1|root,COG0039@2|Bacteria,1TPSY@1239|Firmicutes,248DH@186801|Clostridia,3XZ3D@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	ldh	-	1.1.1.27	ko:K00016	ko00010,ko00270,ko00620,ko00640,ko01100,ko01110,ko01120,ko01130,ko04922,map00010,map00270,map00620,map00640,map01100,map01110,map01120,map01130,map04922	-	R00703,R01000,R03104	RC00031,RC00044	ko00000,ko00001,ko01000,ko04147	-	-	-	Ldh_1_C,Ldh_1_N
NFNHFNFO_03252	33035.JPJF01000089_gene112	1.9e-190	528.0	COG2048@1|root,COG2048@2|Bacteria,1U4JW@1239|Firmicutes,24C8P@186801|Clostridia,3Y1B6@572511|Blautia	186801|Clostridia	C	Cysteine-rich domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03389	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	CCG
NFNHFNFO_03253	33035.JPJF01000089_gene111	5.43e-91	266.0	COG1150@1|root,COG1150@2|Bacteria,1V27J@1239|Firmicutes,24FU5@186801|Clostridia,3Y1I7@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_8
NFNHFNFO_03254	33035.JPJF01000089_gene110	0.0	1288.0	COG1148@1|root,COG1148@2|Bacteria,1VPAD@1239|Firmicutes,25B2G@186801|Clostridia,3Y0ZT@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6	ko:K03388	ko00680,ko01100,ko01120,ko01200,map00680,map01100,map01120,map01200	M00356,M00357,M00563,M00567	R04540,R11928,R11931,R11943,R11944	RC00011	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,Fer4,Fer4_7,Pyr_redox_2
NFNHFNFO_03255	33035.JPJF01000089_gene109	2.02e-106	306.0	COG1908@1|root,COG1908@2|Bacteria,1V7I6@1239|Firmicutes,24JV2@186801|Clostridia,3Y10T@572511|Blautia	186801|Clostridia	C	Methyl-viologen-reducing hydrogenase, delta subunit	-	-	-	-	-	-	-	-	-	-	-	-	FlpD
NFNHFNFO_03256	33035.JPJF01000089_gene108	1.4e-237	652.0	COG1035@1|root,COG4656@1|root,COG1035@2|Bacteria,COG4656@2|Bacteria,1TPBM@1239|Firmicutes,24CJH@186801|Clostridia,3Y13N@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_17,Fer4_8,FrhB_FdhB_C
NFNHFNFO_03257	33035.JPJF01000089_gene107	6.05e-250	686.0	COG0479@1|root,COG0479@2|Bacteria,1TP8R@1239|Firmicutes,247QI@186801|Clostridia,3Y1ET@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4_22
NFNHFNFO_03258	33035.JPJF01000089_gene106	7.62e-215	592.0	COG0543@1|root,COG0543@2|Bacteria,1TQBZ@1239|Firmicutes,248GQ@186801|Clostridia,3Y1HE@572511|Blautia	186801|Clostridia	CH	Oxidoreductase FAD-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DHODB_Fe-S_bind,FAD_binding_6,NAD_binding_1
NFNHFNFO_03259	33035.JPJF01000089_gene105	1.19e-154	434.0	COG4656@1|root,COG4656@2|Bacteria,1UY26@1239|Firmicutes,24D3I@186801|Clostridia,3Y0XC@572511|Blautia	186801|Clostridia	C	2Fe-2S iron-sulfur cluster binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer2_4,Fer4_7,Fer4_9
NFNHFNFO_03260	33035.JPJF01000089_gene104	0.0	986.0	COG1053@1|root,COG1053@2|Bacteria,1TPAR@1239|Firmicutes,247SY@186801|Clostridia,3Y1CZ@572511|Blautia	186801|Clostridia	C	Glucose inhibited division protein A	-	-	1.3.5.1,1.3.5.4,1.3.99.33	ko:K00239,ko:K00244,ko:K17363	ko00020,ko00190,ko00340,ko00620,ko00650,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko02020,ko05134,map00020,map00190,map00340,map00620,map00650,map00720,map01100,map01110,map01120,map01130,map01200,map02020,map05134	M00009,M00011,M00149,M00150,M00173,M00374,M00376	R02164,R10330	RC00045,RC00669	ko00000,ko00001,ko00002,ko01000	-	-	-	FAD_binding_2,FMN_bind,FMN_red
NFNHFNFO_03261	33035.JPJF01000089_gene103	2.76e-205	567.0	COG1951@1|root,COG1951@2|Bacteria,1TPXQ@1239|Firmicutes,248T7@186801|Clostridia,3XZ8S@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	fumA	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
NFNHFNFO_03262	33035.JPJF01000089_gene102	6.3e-129	366.0	COG1838@1|root,COG1838@2|Bacteria,1V1CP@1239|Firmicutes,24FRK@186801|Clostridia,3XZI9@572511|Blautia	186801|Clostridia	C	COG COG1838 Tartrate dehydratase beta subunit Fumarate hydratase class I, C-terminal domain	fumB	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
NFNHFNFO_03263	33035.JPJF01000089_gene101	1.6e-69	209.0	arCOG15062@1|root,32Y8D@2|Bacteria,1VEUQ@1239|Firmicutes,24TKJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	PQ-loop
NFNHFNFO_03264	642492.Clole_0188	5.48e-154	438.0	COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,25B5A@186801|Clostridia	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_28,rve,rve_2
NFNHFNFO_03265	642492.Clole_0189	1.12e-116	338.0	COG2963@1|root,COG2963@2|Bacteria,1TTBJ@1239|Firmicutes,25B7C@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
NFNHFNFO_03266	97139.C824_03119	2.08e-149	437.0	COG0739@1|root,COG0739@2|Bacteria,1TQMQ@1239|Firmicutes,24B3J@186801|Clostridia,36G4K@31979|Clostridiaceae	186801|Clostridia	M	Peptidase family M23	-	-	-	ko:K21472	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Peptidase_M23
NFNHFNFO_03267	33035.JPJF01000032_gene2230	1.25e-169	478.0	29WCR@1|root,30HYE@2|Bacteria,1UUV3@1239|Firmicutes,25KCV@186801|Clostridia,3Y1QM@572511|Blautia	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
NFNHFNFO_03268	33035.JPJF01000032_gene2229	2.81e-267	731.0	COG1063@1|root,COG1063@2|Bacteria,1UI0K@1239|Firmicutes,24ATX@186801|Clostridia	186801|Clostridia	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_03269	33035.JPJF01000032_gene2228	9.23e-245	672.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,3XZP8@572511|Blautia	186801|Clostridia	S	COG COG0656 Aldo keto reductases, related to diketogulonate reductase	-	-	1.1.1.2	ko:K00002	ko00010,ko00040,ko00561,ko00930,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00040,map00561,map00930,map01100,map01110,map01120,map01130,map01220	M00014	R00746,R01041,R01481,R05231	RC00087,RC00088,RC00099,RC00108	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Aldo_ket_red
NFNHFNFO_03270	545694.TREPR_3570	6.64e-161	469.0	COG2211@1|root,COG2211@2|Bacteria	2|Bacteria	G	Major facilitator Superfamily	-	-	-	ko:K03292,ko:K16248	-	-	-	-	ko00000,ko02000	2.A.2	-	-	MFS_2,MFS_3
NFNHFNFO_03271	931626.Awo_c20690	1.22e-137	400.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_03272	33035.JPJF01000032_gene2227	2.39e-228	629.0	COG2221@1|root,COG2221@2|Bacteria,1TR7P@1239|Firmicutes,2493K@186801|Clostridia,3XZCG@572511|Blautia	186801|Clostridia	C	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family	asrC	-	-	ko:K00385	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4,Fer4_10,Fer4_21,Fer4_4,Fer4_6,NIR_SIR,NIR_SIR_ferr
NFNHFNFO_03273	33035.JPJF01000032_gene2226	2.65e-160	451.0	COG0543@1|root,COG0543@2|Bacteria,1TQBZ@1239|Firmicutes,248GQ@186801|Clostridia,3XYPT@572511|Blautia	186801|Clostridia	C	Oxidoreductase NAD-binding domain	asrB	-	-	ko:K16951	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	DHODB_Fe-S_bind,NAD_binding_1
NFNHFNFO_03274	33035.JPJF01000032_gene2225	2.27e-245	673.0	COG0479@1|root,COG0479@2|Bacteria,1TP8R@1239|Firmicutes,247QI@186801|Clostridia,3XZSA@572511|Blautia	186801|Clostridia	C	4Fe-4S dicluster domain	asrA	-	-	ko:K16950	ko00920,ko01120,map00920,map01120	-	R00858,R10146	RC00065	ko00000,ko00001	-	-	-	Fer4_22
NFNHFNFO_03275	33035.JPJF01000032_gene2224	0.0	1063.0	COG3044@1|root,COG3044@2|Bacteria,1TPJ9@1239|Firmicutes,248G5@186801|Clostridia,3XYQT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	ABC_ATPase
NFNHFNFO_03277	33035.JPJF01000032_gene2223	1.54e-281	778.0	COG2186@1|root,COG2188@1|root,COG2186@2|Bacteria,COG2188@2|Bacteria,1TSP3@1239|Firmicutes,24DQE@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
NFNHFNFO_03278	33035.JPJF01000032_gene2222	0.0	1157.0	COG2200@1|root,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia	186801|Clostridia	T	GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,dCache_1
NFNHFNFO_03279	33035.JPJF01000032_gene2221	1.58e-65	206.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1TPUE@1239|Firmicutes,24AS8@186801|Clostridia,3XZK4@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
NFNHFNFO_03280	33035.JPJF01000032_gene2221	5.26e-69	215.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1TPUE@1239|Firmicutes,24AS8@186801|Clostridia,3XZK4@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
NFNHFNFO_03281	33035.JPJF01000032_gene2220	0.0	2479.0	COG2199@1|root,COG2200@1|root,COG2199@2|Bacteria,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia,3Y288@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3
NFNHFNFO_03282	33035.JPJF01000032_gene2219	6.83e-89	261.0	COG3064@1|root,COG3064@2|Bacteria,1VB1V@1239|Firmicutes,25N5W@186801|Clostridia,3Y1TQ@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03283	33035.JPJF01000032_gene2218	1.49e-72	218.0	COG3304@1|root,COG3304@2|Bacteria,1VADH@1239|Firmicutes,24NFV@186801|Clostridia,3Y0CX@572511|Blautia	186801|Clostridia	S	Inner membrane component domain	yccF	-	-	-	-	-	-	-	-	-	-	-	YccF
NFNHFNFO_03284	33035.JPJF01000032_gene2217	0.0	1035.0	COG0246@1|root,COG0246@2|Bacteria,1TQ97@1239|Firmicutes,247TG@186801|Clostridia,3XYQY@572511|Blautia	186801|Clostridia	G	Mannitol dehydrogenase Rossmann domain	-	-	1.1.1.57	ko:K00040	ko00040,ko01100,map00040,map01100	M00061	R02454	RC00085	ko00000,ko00001,ko00002,ko01000	-	-	-	Mannitol_dh,Mannitol_dh_C
NFNHFNFO_03285	33035.JPJF01000032_gene2216	9.2e-270	736.0	COG1312@1|root,COG1312@2|Bacteria,1TP5F@1239|Firmicutes,247RB@186801|Clostridia,3XZ36@572511|Blautia	186801|Clostridia	H	Catalyzes the dehydration of D-mannonate	uxuA	-	4.2.1.8	ko:K01686	ko00040,ko01100,map00040,map01100	M00061	R05606	RC00543	ko00000,ko00001,ko00002,ko01000	-	-	-	UxuA
NFNHFNFO_03286	33035.JPJF01000032_gene2215	2.76e-196	545.0	COG0662@1|root,COG2207@1|root,COG0662@2|Bacteria,COG2207@2|Bacteria,1TPMG@1239|Firmicutes,25E9N@186801|Clostridia,3Y08Q@572511|Blautia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	ARD,AraC_binding,Cupin_2,HTH_18
NFNHFNFO_03287	33035.JPJF01000032_gene2214	1.92e-91	268.0	COG1846@1|root,COG1846@2|Bacteria,1VBKN@1239|Firmicutes,24PC9@186801|Clostridia,3Y216@572511|Blautia	186801|Clostridia	K	Winged helix DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
NFNHFNFO_03288	33035.JPJF01000032_gene2213	1.78e-209	584.0	2C2TA@1|root,2Z7T7@2|Bacteria,1TS53@1239|Firmicutes,248BA@186801|Clostridia,3XZQ0@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	FUSC_2
NFNHFNFO_03289	33035.JPJF01000032_gene2212	5.82e-193	537.0	COG0583@1|root,COG0583@2|Bacteria,1TSNI@1239|Firmicutes,249QS@186801|Clostridia,3XZUG@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_03290	33035.JPJF01000032_gene2211	2.01e-210	585.0	COG2855@1|root,COG2855@2|Bacteria,1TQYA@1239|Firmicutes,247X6@186801|Clostridia,3XZ19@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yeiH	-	-	-	-	-	-	-	-	-	-	-	Cons_hypoth698
NFNHFNFO_03291	33035.JPJF01000032_gene2209	7.81e-113	324.0	COG1528@1|root,COG1528@2|Bacteria,1V1BJ@1239|Firmicutes,24FUF@186801|Clostridia,3XZXQ@572511|Blautia	186801|Clostridia	P	Ferritin-like domain	ftnA	-	1.16.3.2	ko:K02217	-	-	-	-	ko00000,ko01000	-	-	-	Ferritin
NFNHFNFO_03292	33035.JPJF01000032_gene2208	1.61e-203	570.0	COG1476@1|root,COG1476@2|Bacteria,1V7TA@1239|Firmicutes,2496Q@186801|Clostridia,3XZX8@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
NFNHFNFO_03293	33035.JPJF01000032_gene2207	2.31e-80	249.0	COG0524@1|root,COG0524@2|Bacteria,1UYF8@1239|Firmicutes,25MKN@186801|Clostridia,3Y0ZH@572511|Blautia	186801|Clostridia	G	Phosphomethylpyrimidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
NFNHFNFO_03294	33035.JPJF01000032_gene2206	5.31e-156	440.0	COG5523@1|root,COG5523@2|Bacteria,1V6FC@1239|Firmicutes,24JPX@186801|Clostridia,3Y1PP@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF975
NFNHFNFO_03295	33035.JPJF01000032_gene2205	1.36e-130	371.0	COG1309@1|root,COG1309@2|Bacteria,1V89E@1239|Firmicutes,24JQ7@186801|Clostridia,3Y03H@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NFNHFNFO_03296	33035.JPJF01000032_gene2203	9.23e-314	906.0	COG1511@1|root,COG1511@2|Bacteria,1TQ15@1239|Firmicutes,2493H@186801|Clostridia,3XYNF@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01421	-	-	-	-	ko00000	-	-	-	ABC2_membrane_3,DUF3533
NFNHFNFO_03297	33035.JPJF01000032_gene2202	5.8e-169	473.0	COG0204@1|root,COG0204@2|Bacteria,1V9P5@1239|Firmicutes,24K2Z@186801|Clostridia	186801|Clostridia	I	Phosphate acyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase
NFNHFNFO_03298	33035.JPJF01000032_gene2201	2.71e-236	654.0	COG0438@1|root,COG0438@2|Bacteria,1UY0J@1239|Firmicutes,248KC@186801|Clostridia	186801|Clostridia	M	Glycosyl transferase 4-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Acyltransferase,Glyco_transf_4,Glycos_transf_1
NFNHFNFO_03299	33035.JPJF01000032_gene2200	3.66e-66	202.0	COG1321@1|root,COG1321@2|Bacteria,1V3IS@1239|Firmicutes,24MSE@186801|Clostridia,3Y0AY@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	mntR_1	-	-	-	-	-	-	-	-	-	-	-	Fe_dep_repr_C,Fe_dep_repress
NFNHFNFO_03302	742735.HMPREF9467_00001	1.84e-12	73.9	COG0582@1|root,COG0582@2|Bacteria,1V1W1@1239|Firmicutes,24G5V@186801|Clostridia,22105@1506553|Lachnoclostridium	186801|Clostridia	L	Phage integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NFNHFNFO_03303	1121866.AUGK01000004_gene156	1.76e-66	210.0	COG4128@1|root,COG4128@2|Bacteria	2|Bacteria	S	Zonular occludens toxin (Zot)	-	-	-	-	-	-	-	-	-	-	-	-	Zot
NFNHFNFO_03304	394503.Ccel_1571	3.03e-07	50.4	28YRY@1|root,2ZKJC@2|Bacteria,1W60Z@1239|Firmicutes,24UY5@186801|Clostridia,36TX0@31979|Clostridiaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03305	33035.JPJF01000011_gene1307	0.0	1154.0	COG0173@1|root,COG0173@2|Bacteria,1TPCN@1239|Firmicutes,247Z3@186801|Clostridia,3XZ1M@572511|Blautia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12	ko:K01876	ko00970,map00970	M00359,M00360	R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	GAD,tRNA-synt_2,tRNA_anti-codon
NFNHFNFO_03306	33035.JPJF01000011_gene1308	4.57e-291	796.0	COG0124@1|root,COG0124@2|Bacteria,1TP3D@1239|Firmicutes,24852@186801|Clostridia,3XYX1@572511|Blautia	186801|Clostridia	J	Belongs to the class-II aminoacyl-tRNA synthetase family	hisS	-	6.1.1.21	ko:K01892	ko00970,map00970	M00359,M00360	R03655	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_His
NFNHFNFO_03307	33035.JPJF01000011_gene1309	3.92e-119	341.0	COG3437@1|root,COG3437@2|Bacteria,1UHZZ@1239|Firmicutes,25E8P@186801|Clostridia	186801|Clostridia	KT	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HD,HD_5
NFNHFNFO_03308	33035.JPJF01000011_gene1310	0.0	950.0	COG0635@1|root,COG0635@2|Bacteria,1TREM@1239|Firmicutes,247JT@186801|Clostridia,3XZ04@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 9.98	hemZ	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NFNHFNFO_03309	33035.JPJF01000011_gene1311	3.43e-147	414.0	COG0491@1|root,COG0491@2|Bacteria,1V6FA@1239|Firmicutes,24JGV@186801|Clostridia,3Y04N@572511|Blautia	186801|Clostridia	S	COG COG0491 Zn-dependent hydrolases, including glyoxylases	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
NFNHFNFO_03310	33035.JPJF01000011_gene1312	0.0	1474.0	COG0317@1|root,COG0317@2|Bacteria,1TNYZ@1239|Firmicutes,2489A@186801|Clostridia,3XZ3M@572511|Blautia	186801|Clostridia	KT	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance	relA	-	2.7.6.5	ko:K00951	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	iHN637.CLJU_RS16615	ACT_4,HD_4,RelA_SpoT,TGS
NFNHFNFO_03311	33035.JPJF01000011_gene1313	9.82e-118	337.0	COG0503@1|root,COG0503@2|Bacteria,1V1BV@1239|Firmicutes,24HGX@186801|Clostridia,3XZ59@572511|Blautia	186801|Clostridia	F	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis	apt	-	2.4.2.7	ko:K00759	ko00230,ko01100,map00230,map01100	-	R00190,R01229,R04378	RC00063	ko00000,ko00001,ko01000,ko04147	-	-	-	Pribosyltran
NFNHFNFO_03312	33035.JPJF01000011_gene1314	0.0	1073.0	COG0608@1|root,COG0608@2|Bacteria,1TPXE@1239|Firmicutes,247NU@186801|Clostridia,3XZHQ@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	recJ	-	-	ko:K07462	ko03410,ko03430,ko03440,map03410,map03430,map03440	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	DHH,DHHA1
NFNHFNFO_03313	33035.JPJF01000011_gene1315	0.0	1317.0	COG0341@1|root,COG0342@1|root,COG0341@2|Bacteria,COG0342@2|Bacteria,1TQVT@1239|Firmicutes,247X8@186801|Clostridia,3XYSY@572511|Blautia	186801|Clostridia	U	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA	secD	-	-	ko:K03072,ko:K12257	ko02024,ko03060,ko03070,map02024,map03060,map03070	M00335	-	-	ko00000,ko00001,ko00002,ko02044	2.A.6.4,3.A.5.2,3.A.5.7	-	-	SecD_SecF,Sec_GG
NFNHFNFO_03314	33035.JPJF01000011_gene1316	0.0	905.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,248DD@186801|Clostridia,3XZ42@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	scfB	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SPASM
NFNHFNFO_03315	411459.RUMOBE_00561	1.06e-19	80.1	2EGRK@1|root,33AHS@2|Bacteria,1VK9R@1239|Firmicutes,24UM0@186801|Clostridia,3Y0JJ@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score 8.82	scfA	-	-	-	-	-	-	-	-	-	-	-	SCIFF
NFNHFNFO_03316	33035.JPJF01000011_gene1317	1.59e-69	211.0	2E3KV@1|root,32YJ5@2|Bacteria,1VEHD@1239|Firmicutes,24RP3@186801|Clostridia,3Y0RE@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF3792
NFNHFNFO_03317	33035.JPJF01000011_gene1318	2.55e-249	709.0	2ENTE@1|root,33GEK@2|Bacteria,1VSB4@1239|Firmicutes,24YR1@186801|Clostridia,3XZII@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03318	33035.JPJF01000011_gene1319	8.42e-268	736.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3XZS0@572511|Blautia	186801|Clostridia	S	COG COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
NFNHFNFO_03319	33035.JPJF01000011_gene1320	3.7e-150	424.0	COG5578@1|root,COG5578@2|Bacteria,1V3XD@1239|Firmicutes,24K78@186801|Clostridia,3Y06P@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF624
NFNHFNFO_03320	33035.JPJF01000011_gene1321	1.79e-130	372.0	COG1434@1|root,COG1434@2|Bacteria,1V32X@1239|Firmicutes,24ATY@186801|Clostridia,3XZUF@572511|Blautia	186801|Clostridia	S	DUF218 domain	-	-	-	-	-	-	-	-	-	-	-	-	DUF218
NFNHFNFO_03321	33035.JPJF01000011_gene1322	2.17e-102	298.0	COG1443@1|root,COG1443@2|Bacteria,1V41D@1239|Firmicutes,24P77@186801|Clostridia	186801|Clostridia	I	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_7,NUDIX
NFNHFNFO_03322	33035.JPJF01000011_gene1323	0.0	1533.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia,3Y17B@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 2	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFNHFNFO_03323	33035.JPJF01000011_gene1324	3.09e-61	188.0	COG2388@1|root,COG2388@2|Bacteria,1VEEX@1239|Firmicutes,24RI0@186801|Clostridia,3Y1Z7@572511|Blautia	186801|Clostridia	S	GCN5-related N-acetyl-transferase	-	-	-	ko:K06975	-	-	-	-	ko00000	-	-	-	Acetyltransf_CG
NFNHFNFO_03324	33035.JPJF01000011_gene1325	0.0	873.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYKT@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_03325	1298920.KI911353_gene4965	2.09e-42	144.0	COG1846@1|root,COG1846@2|Bacteria,1V9N7@1239|Firmicutes,24NET@186801|Clostridia,220KE@1506553|Lachnoclostridium	186801|Clostridia	K	helix_turn_helix multiple antibiotic resistance protein	-	-	-	-	-	-	-	-	-	-	-	-	MarR,MarR_2
NFNHFNFO_03326	180332.JTGN01000013_gene951	4.21e-81	248.0	COG2364@1|root,COG2364@2|Bacteria,1UXHA@1239|Firmicutes,24AJQ@186801|Clostridia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score	-	-	-	ko:K07149	-	-	-	-	ko00000	-	-	-	Cytidylate_kin2
NFNHFNFO_03327	33035.JPJF01000011_gene1326	8.63e-189	525.0	COG1307@1|root,COG1307@2|Bacteria,1TSKD@1239|Firmicutes,24AE9@186801|Clostridia,3XYU8@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DegV
NFNHFNFO_03328	33035.JPJF01000011_gene1327	2.36e-112	323.0	2C2B5@1|root,32RA4@2|Bacteria,1V6P1@1239|Firmicutes,24N51@186801|Clostridia,3Y05S@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03329	33035.JPJF01000011_gene1328	1.57e-207	575.0	29WCP@1|root,30HYB@2|Bacteria,1VV7Y@1239|Firmicutes,250AD@186801|Clostridia,3Y24P@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03330	33035.JPJF01000011_gene1329	8.52e-186	518.0	COG2816@1|root,COG2816@2|Bacteria,1TRMF@1239|Firmicutes,24AXA@186801|Clostridia,3XZJ4@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	nudC	-	3.6.1.22	ko:K03426	ko00760,ko01100,ko04146,map00760,map01100,map04146	-	R00103,R03004,R11104	RC00002	ko00000,ko00001,ko01000	-	-	-	NUDIX,NUDIX-like,zf-NADH-PPase
NFNHFNFO_03331	33035.JPJF01000011_gene1330	6.52e-149	420.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_03332	33035.JPJF01000011_gene1331	0.0	1381.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,25M7M@186801|Clostridia,3Y1DH@572511|Blautia	186801|Clostridia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
NFNHFNFO_03333	33035.JPJF01000011_gene1332	2.24e-194	550.0	COG5002@1|root,COG5002@2|Bacteria,1UHZU@1239|Firmicutes,25E8I@186801|Clostridia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_03334	33035.JPJF01000011_gene1333	1.82e-134	384.0	COG0745@1|root,COG0745@2|Bacteria,1TT71@1239|Firmicutes,24CAY@186801|Clostridia	186801|Clostridia	T	Response regulator receiver domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_03335	33035.JPJF01000011_gene1334	4.36e-35	120.0	COG1476@1|root,COG1476@2|Bacteria,1VERT@1239|Firmicutes,24QJJ@186801|Clostridia,3Y0N3@572511|Blautia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	ko:K07729	-	-	-	-	ko00000,ko03000	-	-	-	HTH_3
NFNHFNFO_03336	33035.JPJF01000011_gene1335	2.5e-44	146.0	2EQKA@1|root,3387H@2|Bacteria,1VJF1@1239|Firmicutes	1239|Firmicutes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03337	33035.JPJF01000011_gene1336	0.0	1286.0	COG0326@1|root,COG0326@2|Bacteria,1TQEU@1239|Firmicutes,247ND@186801|Clostridia,3XZ94@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score	htpG	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c,HATPase_c_3,HSP90
NFNHFNFO_03338	33035.JPJF01000011_gene1337	2.92e-147	415.0	COG0500@1|root,COG2226@2|Bacteria,1V9WG@1239|Firmicutes,24JGT@186801|Clostridia,3Y1GH@572511|Blautia	186801|Clostridia	Q	DREV methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25,Methyltransf_31
NFNHFNFO_03339	33035.JPJF01000011_gene1338	4.94e-310	847.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,3XZHG@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	ywdH	-	1.2.1.3,1.2.99.10	ko:K00128,ko:K22445	ko00010,ko00053,ko00071,ko00280,ko00310,ko00330,ko00340,ko00380,ko00410,ko00561,ko00620,ko00625,ko00903,ko00981,ko01100,ko01110,ko01120,ko01130,map00010,map00053,map00071,map00280,map00310,map00330,map00340,map00380,map00410,map00561,map00620,map00625,map00903,map00981,map01100,map01110,map01120,map01130	M00135	R00264,R00631,R00710,R00904,R01752,R01986,R02549,R02678,R02940,R02957,R03283,R03869,R04065,R04506,R04903,R05050,R05237,R05238,R05286,R06366,R08146	RC00047,RC00071,RC00080,RC00186,RC00218,RC00242,RC00816,RC01500	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
NFNHFNFO_03340	33035.JPJF01000011_gene1339	1.35e-51	163.0	2E51P@1|root,32ZV2@2|Bacteria,1VFYG@1239|Firmicutes,24QWN@186801|Clostridia,3Y0D9@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03341	33035.JPJF01000011_gene1340	3.12e-178	497.0	COG0561@1|root,COG0561@2|Bacteria,1V43V@1239|Firmicutes,24AQQ@186801|Clostridia,3XZTP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NFNHFNFO_03342	33035.JPJF01000011_gene1341	7.09e-153	430.0	COG0546@1|root,COG0546@2|Bacteria,1V3YI@1239|Firmicutes,24CRF@186801|Clostridia,3XZXU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	gph	-	3.1.3.18	ko:K01091	ko00630,ko01100,ko01110,ko01130,map00630,map01100,map01110,map01130	-	R01334	RC00017	ko00000,ko00001,ko01000	-	-	-	HAD_2
NFNHFNFO_03343	33035.JPJF01000011_gene1342	2.28e-116	335.0	COG0424@1|root,COG0424@2|Bacteria,1V6FH@1239|Firmicutes,24JRN@186801|Clostridia,3Y041@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	maf	-	-	ko:K06287	-	-	-	-	ko00000	-	-	-	Maf
NFNHFNFO_03344	33035.JPJF01000011_gene1343	2.27e-178	498.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,24PNN@186801|Clostridia	186801|Clostridia	S	HAD-superfamily hydrolase, subfamily IIB	yidA	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NFNHFNFO_03345	33035.JPJF01000011_gene1344	5.77e-26	104.0	2DK69@1|root,308PY@2|Bacteria,1UF6U@1239|Firmicutes,25K7P@186801|Clostridia,3Y1Z6@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03346	33035.JPJF01000011_gene1345	1.71e-162	456.0	COG1116@1|root,COG1116@2|Bacteria,1TSW5@1239|Firmicutes,25AZG@186801|Clostridia,3Y1BI@572511|Blautia	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NFNHFNFO_03347	33035.JPJF01000011_gene1346	2.36e-220	610.0	COG0715@1|root,COG0715@2|Bacteria,1TPAD@1239|Firmicutes,24A2V@186801|Clostridia,3Y0X4@572511|Blautia	186801|Clostridia	P	NMT1/THI5 like	-	-	-	-	-	-	-	-	-	-	-	-	NMT1
NFNHFNFO_03348	33035.JPJF01000011_gene1347	1.4e-161	454.0	COG0600@1|root,COG0600@2|Bacteria,1TRFD@1239|Firmicutes,25C7Z@186801|Clostridia,3Y16M@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_03349	33035.JPJF01000011_gene1348	7.57e-63	192.0	COG0011@1|root,COG0011@2|Bacteria,1VC4R@1239|Firmicutes,24MY3@186801|Clostridia,3Y1QW@572511|Blautia	186801|Clostridia	S	Thiamine-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	Thiamine_BP
NFNHFNFO_03350	33035.JPJF01000011_gene1352	3.35e-312	855.0	COG1167@1|root,COG1167@2|Bacteria,1TPS5@1239|Firmicutes,248ZB@186801|Clostridia,3XYXZ@572511|Blautia	186801|Clostridia	K	COG COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs	-	-	-	ko:K00375	-	-	-	-	ko00000,ko03000	-	-	-	Aminotran_1_2,GntR
NFNHFNFO_03351	33035.JPJF01000011_gene1353	0.0	1133.0	COG0008@1|root,COG0008@2|Bacteria,1TP8G@1239|Firmicutes,247Y0@186801|Clostridia,3XYKW@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	glnS	-	6.1.1.18	ko:K01886	ko00970,ko01100,map00970,map01100	M00359,M00360	R03652	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1c,tRNA-synt_1c_C
NFNHFNFO_03352	33035.JPJF01000011_gene1354	0.0	1874.0	COG0493@1|root,COG1145@1|root,COG0493@2|Bacteria,COG1145@2|Bacteria,1TPR4@1239|Firmicutes,248TM@186801|Clostridia,3XYRC@572511|Blautia	186801|Clostridia	C	COG COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductases	-	-	1.97.1.9	ko:K12527	ko00450,map00450	-	R07229	RC02420	ko00000,ko00001,ko01000	-	-	-	Fer4_20,Pyr_redox_2,Pyr_redox_3
NFNHFNFO_03353	33035.JPJF01000011_gene1355	0.0	894.0	COG0402@1|root,COG0402@2|Bacteria,1TP43@1239|Firmicutes,248IX@186801|Clostridia,3XZEP@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	ssnA	-	3.5.4.40	ko:K20810	ko00130,ko01110,map00130,map01110	-	R10695	RC00477	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1
NFNHFNFO_03354	33035.JPJF01000011_gene1356	1.46e-96	281.0	COG2050@1|root,COG2050@2|Bacteria,1UI00@1239|Firmicutes,24U68@186801|Clostridia,3Y0GY@572511|Blautia	186801|Clostridia	Q	Thioesterase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	4HBT
NFNHFNFO_03355	33035.JPJF01000011_gene1357	0.0	1205.0	COG1455@1|root,COG2200@1|root,COG1455@2|Bacteria,COG2200@2|Bacteria,1TP8D@1239|Firmicutes,24808@186801|Clostridia,3Y1VT@572511|Blautia	186801|Clostridia	G	Phosphotransferase system, EIIC	-	-	-	-	-	-	-	-	-	-	-	-	EAL,PTS_EIIC
NFNHFNFO_03356	33035.JPJF01000011_gene1358	2.72e-154	435.0	COG0101@1|root,COG0101@2|Bacteria,1TQUY@1239|Firmicutes,248GJ@186801|Clostridia,3Y02U@572511|Blautia	186801|Clostridia	J	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs	truA1	-	5.4.99.12	ko:K06173	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	PseudoU_synth_1
NFNHFNFO_03357	33035.JPJF01000011_gene1359	0.0	919.0	COG1350@1|root,COG1350@2|Bacteria,1UI01@1239|Firmicutes,25E8Q@186801|Clostridia,3Y13X@572511|Blautia	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	trpB	-	4.2.1.20	ko:K06001	ko00260,ko00400,ko01100,ko01110,ko01130,ko01230,map00260,map00400,map01100,map01110,map01130,map01230	M00023	R00674,R02340,R02722	RC00209,RC00210,RC00700,RC00701,RC02868	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NFNHFNFO_03358	1410661.JNKW01000006_gene230	3.85e-130	381.0	COG1442@1|root,COG1442@2|Bacteria,1UY89@1239|Firmicutes,249RV@186801|Clostridia	186801|Clostridia	M	family 8	-	-	-	-	-	-	-	-	-	-	-	-	Cys_rich_CPCC,Glyco_transf_8
NFNHFNFO_03359	742723.HMPREF9477_00065	1.98e-206	577.0	COG0562@1|root,COG0562@2|Bacteria,1TQB9@1239|Firmicutes,249BR@186801|Clostridia,27IA3@186928|unclassified Lachnospiraceae	186801|Clostridia	M	UDP-galactopyranose mutase	glf	-	5.4.99.9	ko:K01854	ko00052,ko00520,map00052,map00520	-	R00505,R09009	RC00317,RC02396	ko00000,ko00001,ko01000	-	-	-	GLF,NAD_binding_8
NFNHFNFO_03360	1410661.JNKW01000006_gene225	1.57e-129	375.0	COG3475@1|root,COG3475@2|Bacteria,1V0P4@1239|Firmicutes,25B2A@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
NFNHFNFO_03361	1410661.JNKW01000006_gene224	1.71e-152	445.0	COG2244@1|root,COG2244@2|Bacteria,1UYWC@1239|Firmicutes,25CW4@186801|Clostridia	186801|Clostridia	S	Polysaccharide biosynthesis protein	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
NFNHFNFO_03362	1336241.JAEB01000001_gene154	9.15e-108	338.0	COG0463@1|root,COG0463@2|Bacteria	2|Bacteria	M	Glycosyl transferase, family 2	-	-	2.7.8.20	ko:K01002,ko:K20534	ko01100,map01100	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.2.1.9	GT2	-	GT87,Glycos_transf_2
NFNHFNFO_03363	33035.JPJF01000067_gene3546	4.15e-125	360.0	COG1216@1|root,COG1216@2|Bacteria,1TS11@1239|Firmicutes,24BQ6@186801|Clostridia,3Y08Z@572511|Blautia	186801|Clostridia	S	Glycosyltransferase like family 2	-	-	2.4.1.83	ko:K00721,ko:K00786	ko00510,ko01100,map00510,map01100	-	R01009	RC00005	ko00000,ko00001,ko01000,ko01003	-	GT2	-	Glycos_transf_2
NFNHFNFO_03364	33035.JPJF01000067_gene3547	6.78e-46	152.0	COG2456@1|root,COG2456@2|Bacteria,1VGMQ@1239|Firmicutes,24NPY@186801|Clostridia,3Y0U7@572511|Blautia	186801|Clostridia	S	Uncharacterized conserved protein (DUF2304)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2304
NFNHFNFO_03365	411461.DORFOR_00958	3.31e-79	271.0	COG4713@1|root,COG4713@2|Bacteria,1UY68@1239|Firmicutes,24A5N@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142
NFNHFNFO_03366	33035.JPJF01000067_gene3550	2.21e-174	501.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3XZCB@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NFNHFNFO_03367	33035.JPJF01000067_gene3551	8.57e-128	363.0	COG1898@1|root,COG1898@2|Bacteria,1TRVB@1239|Firmicutes,248VX@186801|Clostridia,3XYH7@572511|Blautia	186801|Clostridia	G	Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose	rfbC	-	5.1.3.13	ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R06514	RC01531	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS02630,iHN637.CLJU_RS02745	dTDP_sugar_isom
NFNHFNFO_03368	33035.JPJF01000067_gene3552	8.75e-152	430.0	COG1682@1|root,COG1682@2|Bacteria,1TQZF@1239|Firmicutes,248R0@186801|Clostridia,3XZE2@572511|Blautia	186801|Clostridia	GM	ABC-2 type transporter	-	-	-	ko:K09692	ko02010,map02010	M00251	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.104	-	-	ABC2_membrane
NFNHFNFO_03369	622312.ROSEINA2194_02599	2.05e-204	577.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia	186801|Clostridia	GM	ABC-type polysaccharide polyol phosphate transport system ATPase component	-	-	3.6.3.40	ko:K01990,ko:K09691,ko:K09693	ko02010,map02010	M00250,M00251,M00254	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1,3.A.1.103,3.A.1.104	-	-	ABC_tran,Wzt_C
NFNHFNFO_03370	622312.ROSEINA2194_02598	0.0	1199.0	COG0463@1|root,COG1216@1|root,COG3754@1|root,COG0463@2|Bacteria,COG1216@2|Bacteria,COG3754@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
NFNHFNFO_03371	622312.ROSEINA2194_02597	5.12e-146	419.0	COG2242@1|root,COG2242@2|Bacteria,1TPEE@1239|Firmicutes,24D9B@186801|Clostridia	186801|Clostridia	H	Methyltransferase domain	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_12,Methyltransf_23,Methyltransf_25
NFNHFNFO_03372	622312.ROSEINA2194_02596	3.35e-63	218.0	COG0030@1|root,COG0030@2|Bacteria,1V28P@1239|Firmicutes	1239|Firmicutes	J	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03373	33035.JPJF01000067_gene3555	0.0	1110.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3XYQA@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
NFNHFNFO_03374	33035.JPJF01000067_gene3556	2.12e-248	692.0	COG1807@1|root,COG1807@2|Bacteria,1V22V@1239|Firmicutes,24GKH@186801|Clostridia,3XYRT@572511|Blautia	186801|Clostridia	M	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family	-	-	-	-	-	-	-	-	-	-	-	-	DUF2142,PMT,PMT_2
NFNHFNFO_03375	33035.JPJF01000067_gene3557	1.19e-210	584.0	COG0463@1|root,COG0463@2|Bacteria,1TPR3@1239|Firmicutes,248Q5@186801|Clostridia,3XYSZ@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NFNHFNFO_03376	33035.JPJF01000067_gene3558	0.0	1144.0	COG1215@1|root,COG1216@1|root,COG1215@2|Bacteria,COG1216@2|Bacteria,1TQU0@1239|Firmicutes,248HP@186801|Clostridia,3XYRF@572511|Blautia	186801|Clostridia	M	Glycosyltransferase like family	-	-	-	ko:K20444	-	-	-	-	ko00000,ko01000,ko01005,ko02000	4.D.1.3	GT2,GT4	-	Glycos_transf_2
NFNHFNFO_03377	33035.JPJF01000067_gene3559	2.15e-192	537.0	COG1216@1|root,COG1216@2|Bacteria,1TSTE@1239|Firmicutes,249WH@186801|Clostridia,3XYQG@572511|Blautia	186801|Clostridia	M	Glycosyl transferase family group 2	-	-	-	ko:K07011	-	-	-	-	ko00000	-	-	-	Glycos_transf_2
NFNHFNFO_03378	1304866.K413DRAFT_0291	1.23e-193	552.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,36GR6@31979|Clostridiaceae	186801|Clostridia	M	Exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
NFNHFNFO_03379	622312.ROSEINA2194_02588	4.89e-91	277.0	COG1215@1|root,COG1215@2|Bacteria,1V1CB@1239|Firmicutes,24EMU@186801|Clostridia	186801|Clostridia	M	Glycosyltransferase, group 2 family protein	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NFNHFNFO_03380	929506.CbC4_0708	1.94e-36	143.0	COG3475@1|root,COG3475@2|Bacteria,1VBSV@1239|Firmicutes,24C5H@186801|Clostridia,36EWJ@31979|Clostridiaceae	186801|Clostridia	M	LICD family	licD	-	-	ko:K07271	-	-	-	-	ko00000,ko01000	-	-	-	LicD
NFNHFNFO_03381	1384065.JAGS01000001_gene2797	9.62e-89	283.0	COG1887@1|root,COG1887@2|Bacteria,1TP75@1239|Firmicutes,24ED0@186801|Clostridia,3WKZI@541000|Ruminococcaceae	186801|Clostridia	M	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase	-	-	2.7.8.12	ko:K09809	-	-	-	-	ko00000,ko01000	-	-	-	Glyphos_transf
NFNHFNFO_03382	411489.CLOL250_00069	1.02e-121	354.0	COG1682@1|root,COG1682@2|Bacteria,1V1J2@1239|Firmicutes,25B57@186801|Clostridia,36WAG@31979|Clostridiaceae	186801|Clostridia	GM	Transport permease protein	-	-	-	ko:K01992,ko:K09690	ko02010,map02010	M00250,M00254	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.103	-	-	ABC2_membrane
NFNHFNFO_03383	1232447.BAHW02000008_gene237	6.94e-124	358.0	COG1134@1|root,COG1134@2|Bacteria,1TQKK@1239|Firmicutes,24A5V@186801|Clostridia,26AXS@186813|unclassified Clostridiales	186801|Clostridia	GM	ATPases associated with a variety of cellular activities	rfbB	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_03384	1235802.C823_02121	6.76e-216	619.0	COG1887@1|root,COG1887@2|Bacteria,1TSTN@1239|Firmicutes,24AA5@186801|Clostridia,25VZJ@186806|Eubacteriaceae	186801|Clostridia	M	teichoic acid biosynthesis protein B	-	-	2.7.8.14,2.7.8.47	ko:K18704	-	-	R11614,R11621	-	ko00000,ko01000	-	-	-	Glycos_transf_2,Glyphos_transf
NFNHFNFO_03385	1235802.C823_02122	1.05e-135	389.0	COG1211@1|root,COG1211@2|Bacteria,1V3M7@1239|Firmicutes,248E6@186801|Clostridia,25W5N@186806|Eubacteriaceae	186801|Clostridia	I	Catalyzes the transfer of the cytidylyl group of CTP to D-ribitol 5-phosphate	-	-	2.7.7.60	ko:K00991	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,adh_short
NFNHFNFO_03386	888821.HMPREF9394_0277	1.09e-132	390.0	COG0451@1|root,COG0451@2|Bacteria,1TS59@1239|Firmicutes,4HC1B@91061|Bacilli,1WRNJ@1305|Streptococcus sanguinis	91061|Bacilli	M	NAD(P)H-binding	-	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	Epimerase
NFNHFNFO_03387	649764.HMPREF0762_01742	1.58e-38	148.0	COG1835@1|root,COG1835@2|Bacteria	2|Bacteria	I	transferase activity, transferring acyl groups other than amino-acyl groups	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NFNHFNFO_03388	1235793.C809_01442	1.37e-227	632.0	COG3547@1|root,COG3547@2|Bacteria,1TPSP@1239|Firmicutes,24AH4@186801|Clostridia,27TFA@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
NFNHFNFO_03390	33035.JPJF01000060_gene2422	1.25e-231	642.0	COG0420@1|root,COG0420@2|Bacteria,1TQY6@1239|Firmicutes,248VE@186801|Clostridia,3XYWR@572511|Blautia	186801|Clostridia	L	SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity	sbcD	-	-	ko:K03547	-	-	-	-	ko00000,ko03400	-	-	-	Metallophos,SbcD_C
NFNHFNFO_03391	33035.JPJF01000060_gene2421	1.83e-194	540.0	COG0656@1|root,COG0656@2|Bacteria,1TPM1@1239|Firmicutes,248FK@186801|Clostridia,3XYQK@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yvgN	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NFNHFNFO_03392	33035.JPJF01000060_gene2420	1.22e-246	682.0	COG0577@1|root,COG0577@2|Bacteria,1TPUU@1239|Firmicutes,2483J@186801|Clostridia,3XZ8E@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	macB2	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NFNHFNFO_03393	33035.JPJF01000060_gene2419	2.85e-200	578.0	COG0845@1|root,COG0845@2|Bacteria,1UZA4@1239|Firmicutes,24BV0@186801|Clostridia,3XZ43@572511|Blautia	186801|Clostridia	M	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family	-	-	-	ko:K02005	-	-	-	-	ko00000	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NFNHFNFO_03394	33035.JPJF01000060_gene2418	5.43e-167	468.0	COG1136@1|root,COG1136@2|Bacteria,1TPBJ@1239|Firmicutes,248EZ@186801|Clostridia,3XYST@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	macB	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_03395	33035.JPJF01000060_gene2417	1.17e-226	626.0	COG0240@1|root,COG0240@2|Bacteria,1TQ5P@1239|Firmicutes,248JT@186801|Clostridia,3XYNR@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	gpsA	-	1.1.1.94	ko:K00057	ko00564,ko01110,map00564,map01110	-	R00842,R00844	RC00029	ko00000,ko00001,ko01000	-	-	-	NAD_Gly3P_dh_C,NAD_Gly3P_dh_N
NFNHFNFO_03396	33035.JPJF01000060_gene2416	1.29e-148	418.0	COG0344@1|root,COG0344@2|Bacteria,1VA3J@1239|Firmicutes,24JA2@186801|Clostridia,3XZ7V@572511|Blautia	186801|Clostridia	I	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP	plsY	-	2.3.1.15	ko:K08591	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R00851,R09380	RC00004,RC00039,RC00041	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	G3P_acyltransf
NFNHFNFO_03397	33035.JPJF01000060_gene2415	4.39e-297	812.0	COG1160@1|root,COG1160@2|Bacteria,1TPNM@1239|Firmicutes,2493T@186801|Clostridia,3XZ3Z@572511|Blautia	186801|Clostridia	S	GTPase that plays an essential role in the late steps of ribosome biogenesis	der	-	-	ko:K03977	-	-	-	-	ko00000,ko03009	-	-	-	KH_dom-like,MMR_HSR1
NFNHFNFO_03398	33035.JPJF01000060_gene2414	1.1e-312	854.0	COG1625@1|root,COG1625@2|Bacteria,1TSFU@1239|Firmicutes,247JK@186801|Clostridia,3XYRJ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF512
NFNHFNFO_03399	33035.JPJF01000060_gene2413	9.08e-280	764.0	COG0462@1|root,COG0462@2|Bacteria,1TQ6Q@1239|Firmicutes,248ZN@186801|Clostridia,3XYPC@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	prs	-	2.7.6.1	ko:K00948	ko00030,ko00230,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00230,map01100,map01110,map01120,map01130,map01200,map01230	M00005	R01049	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	Pribosyltran,Pribosyltran_N
NFNHFNFO_03400	33035.JPJF01000060_gene2412	1.69e-138	408.0	COG3584@1|root,COG3883@1|root,COG3584@2|Bacteria,COG3883@2|Bacteria,1UI15@1239|Firmicutes,25EA3@186801|Clostridia,3XZ75@572511|Blautia	186801|Clostridia	S	Psort location Extracellular, score	-	-	-	ko:K21471	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	-
NFNHFNFO_03401	33035.JPJF01000060_gene2411	2.74e-180	505.0	COG1496@1|root,COG1496@2|Bacteria,1TS34@1239|Firmicutes,248TD@186801|Clostridia,3XYQB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfiH	-	-	ko:K05810	-	-	-	-	ko00000,ko01000	-	-	-	Cu-oxidase_4
NFNHFNFO_03402	33035.JPJF01000060_gene2410	4.81e-69	209.0	COG0792@1|root,COG0792@2|Bacteria,1VFHQ@1239|Firmicutes,24QNK@186801|Clostridia,3Y0HI@572511|Blautia	186801|Clostridia	L	Belongs to the UPF0102 family	-	-	-	ko:K07460	-	-	-	-	ko00000	-	-	-	UPF0102
NFNHFNFO_03403	33035.JPJF01000060_gene2409	1.89e-159	449.0	COG0164@1|root,COG0164@2|Bacteria,1V1D6@1239|Firmicutes,248IT@186801|Clostridia,3XZF8@572511|Blautia	186801|Clostridia	L	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids	rnhB	-	3.1.26.4	ko:K03470	ko03030,map03030	-	-	-	ko00000,ko00001,ko01000,ko03032	-	-	-	RNase_HII
NFNHFNFO_03404	33035.JPJF01000060_gene2408	1.56e-182	509.0	COG1161@1|root,COG1161@2|Bacteria,1TQGK@1239|Firmicutes,2490H@186801|Clostridia,3XYWP@572511|Blautia	186801|Clostridia	S	Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity	ylqF	-	-	ko:K14540	-	-	-	-	ko00000,ko03009	-	-	-	MMR_HSR1
NFNHFNFO_03405	33035.JPJF01000060_gene2407	2.35e-126	360.0	COG0681@1|root,COG0681@2|Bacteria,1V2SF@1239|Firmicutes,24AWM@186801|Clostridia,3XZTM@572511|Blautia	186801|Clostridia	U	Signal peptidase, peptidase S26	-	-	3.4.21.89	ko:K03100	ko02024,ko03060,map02024,map03060	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_S24
NFNHFNFO_03406	33035.JPJF01000060_gene2406	5.73e-75	224.0	COG0335@1|root,COG0335@2|Bacteria,1V6FT@1239|Firmicutes,24J83@186801|Clostridia,3Y019@572511|Blautia	186801|Clostridia	J	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site	rplS	-	-	ko:K02884	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L19
NFNHFNFO_03407	33035.JPJF01000060_gene2405	2.06e-82	249.0	COG4767@1|root,COG4767@2|Bacteria,1VHCV@1239|Firmicutes,24RMJ@186801|Clostridia,3Y0NZ@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	VanZ
NFNHFNFO_03408	33035.JPJF01000060_gene2404	3.09e-209	579.0	COG1209@1|root,COG1209@2|Bacteria,1V301@1239|Firmicutes,247XE@186801|Clostridia,3XZAG@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis	rfbA	-	2.7.7.24	ko:K00973	ko00521,ko00523,ko00525,ko01130,map00521,map00523,map00525,map01130	M00793	R02328	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	NTP_transferase
NFNHFNFO_03409	33035.JPJF01000060_gene2403	1.4e-206	571.0	COG1091@1|root,COG1091@2|Bacteria,1TP71@1239|Firmicutes,247PG@186801|Clostridia,3XZI0@572511|Blautia	186801|Clostridia	M	Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose	rfbD	-	1.1.1.133,5.1.3.13	ko:K00067,ko:K01790	ko00521,ko00523,ko01130,map00521,map00523,map01130	M00793	R02777,R06514	RC00182,RC01531	ko00000,ko00001,ko00002,ko01000	-	-	-	RmlD_sub_bind
NFNHFNFO_03410	33035.JPJF01000060_gene2402	2.55e-268	736.0	COG0500@1|root,COG0789@1|root,COG0789@2|Bacteria,COG2226@2|Bacteria,1TSDZ@1239|Firmicutes,248EY@186801|Clostridia,3Y1FI@572511|Blautia	186801|Clostridia	KQ	helix_turn_helix, mercury resistance	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_11,Methyltransf_25,Methyltransf_31
NFNHFNFO_03411	33035.JPJF01000060_gene2401	4.14e-259	708.0	COG1088@1|root,COG1088@2|Bacteria,1TPWM@1239|Firmicutes,247NE@186801|Clostridia,3XZ56@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	rfbB	-	4.2.1.46	ko:K01710	ko00521,ko00523,ko00525,ko01055,ko01130,map00521,map00523,map00525,map01055,map01130	M00793	R06513	RC00402	ko00000,ko00001,ko00002,ko01000	-	-	-	GDP_Man_Dehyd
NFNHFNFO_03412	33035.JPJF01000060_gene2400	3.65e-117	337.0	2AYEN@1|root,31QHP@2|Bacteria,1V7VT@1239|Firmicutes,24JY6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03413	33035.JPJF01000060_gene2399	1.12e-196	550.0	COG1316@1|root,COG1316@2|Bacteria,1UY3P@1239|Firmicutes,24H37@186801|Clostridia,3Y00F@572511|Blautia	186801|Clostridia	K	Cell envelope-related transcriptional attenuator domain	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
NFNHFNFO_03414	33035.JPJF01000060_gene2398	8.97e-140	400.0	COG4509@1|root,COG4509@2|Bacteria,1V4RE@1239|Firmicutes,24JWD@186801|Clostridia,3XZZZ@572511|Blautia	186801|Clostridia	S	Sortase family	-	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NFNHFNFO_03415	33035.JPJF01000060_gene2397	1.7e-162	457.0	COG3944@1|root,COG3944@2|Bacteria,1UZCR@1239|Firmicutes,24HS8@186801|Clostridia,3Y0BB@572511|Blautia	186801|Clostridia	M	Chain length determinant protein	-	-	-	-	-	-	-	-	-	-	-	-	GNVR,Wzz
NFNHFNFO_03416	33035.JPJF01000060_gene2396	3.86e-143	406.0	COG0489@1|root,COG0489@2|Bacteria,1TS4R@1239|Firmicutes,24B0Z@186801|Clostridia,3XZU6@572511|Blautia	186801|Clostridia	D	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
NFNHFNFO_03417	33035.JPJF01000060_gene2395	5.72e-161	451.0	COG4464@1|root,COG4464@2|Bacteria,1TQ1T@1239|Firmicutes,24JQU@186801|Clostridia,3XZY8@572511|Blautia	186801|Clostridia	GM	Psort location Cytoplasmic, score 8.87	-	-	3.1.3.48	ko:K01104	-	-	-	-	ko00000,ko01000	-	-	-	-
NFNHFNFO_03418	33035.JPJF01000060_gene2394	2.51e-125	364.0	29VW1@1|root,30HDW@2|Bacteria,1UHIW@1239|Firmicutes,25QAG@186801|Clostridia,3Y1RQ@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF5011)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5011
NFNHFNFO_03420	33035.JPJF01000060_gene2391	2.11e-55	173.0	29WCW@1|root,30HYJ@2|Bacteria,1UUVE@1239|Firmicutes,2596R@186801|Clostridia,3Y25S@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03422	565664.EFXG_00702	3.38e-25	105.0	COG0119@1|root,COG0119@2|Bacteria,1TS0A@1239|Firmicutes,4HEYD@91061|Bacilli	91061|Bacilli	E	Nucleoid-structuring protein H-NS	-	-	4.1.3.39	ko:K01666	ko00360,ko00362,ko00621,ko00622,ko01100,ko01120,ko01220,map00360,map00362,map00621,map00622,map01100,map01120,map01220	M00545,M00569	R00750	RC00307,RC00371	br01602,ko00000,ko00001,ko00002,ko01000	-	-	-	HMGL-like
NFNHFNFO_03425	397288.C806_00771	1.36e-07	62.8	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,27J2F@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
NFNHFNFO_03428	478749.BRYFOR_09694	3.49e-73	245.0	COG5283@1|root,COG5412@1|root,COG5283@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia	186801|Clostridia	E	Phage tail tape measure protein, TP901 family	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail
NFNHFNFO_03429	33035.JPJF01000042_gene401	1.41e-99	289.0	COG4506@1|root,COG4506@2|Bacteria,1V8CS@1239|Firmicutes,24JQR@186801|Clostridia,3Y0D5@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	ywiB	-	-	-	-	-	-	-	-	-	-	-	DUF1934
NFNHFNFO_03430	33035.JPJF01000042_gene400	3.66e-187	521.0	COG0796@1|root,COG0796@2|Bacteria,1TPPR@1239|Firmicutes,249MB@186801|Clostridia,3XZR8@572511|Blautia	186801|Clostridia	M	Provides the (R)-glutamate required for cell wall biosynthesis	murI	-	5.1.1.3	ko:K01776	ko00471,ko01100,map00471,map01100	-	R00260	RC00302	ko00000,ko00001,ko01000,ko01011	-	-	-	Asp_Glu_race
NFNHFNFO_03431	33035.JPJF01000042_gene399	8.89e-133	379.0	2AUKD@1|root,31K93@2|Bacteria,1V6PK@1239|Firmicutes,24J91@186801|Clostridia,3Y092@572511|Blautia	186801|Clostridia	S	Stage II sporulation protein R (spore_II_R)	spoIIR	-	-	ko:K06387	-	-	-	-	ko00000	-	-	-	Spore_II_R
NFNHFNFO_03432	33035.JPJF01000042_gene398	5.8e-129	368.0	29WCV@1|root,30HYI@2|Bacteria,1UFR5@1239|Firmicutes,25MHY@186801|Clostridia,3Y1VN@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03433	33035.JPJF01000042_gene397	1.51e-239	660.0	COG0531@1|root,COG0531@2|Bacteria	2|Bacteria	E	amino acid	-	-	-	-	-	-	-	-	-	-	-	-	Spore_permease
NFNHFNFO_03434	33035.JPJF01000042_gene396	0.0	937.0	COG0697@1|root,COG0697@2|Bacteria,1TP7K@1239|Firmicutes,248Q8@186801|Clostridia,3XZAJ@572511|Blautia	186801|Clostridia	EG	Psort location CytoplasmicMembrane, score	gerA	-	-	ko:K06310	-	-	-	-	ko00000	-	-	-	GerA
NFNHFNFO_03435	33035.JPJF01000042_gene395	2.87e-146	413.0	COG1802@1|root,COG1802@2|Bacteria,1TSV2@1239|Firmicutes,24C0U@186801|Clostridia,3XZAU@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	GntR	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NFNHFNFO_03436	33035.JPJF01000042_gene394	6.3e-206	570.0	COG1947@1|root,COG1947@2|Bacteria,1TPXV@1239|Firmicutes,24898@186801|Clostridia,3XZ86@572511|Blautia	186801|Clostridia	H	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol	ispE	-	2.7.1.148	ko:K00919	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05634	RC00002,RC01439	ko00000,ko00001,ko00002,ko01000	-	-	-	GHMP_kinases_C,GHMP_kinases_N
NFNHFNFO_03437	33035.JPJF01000042_gene393	0.0	993.0	COG1388@1|root,COG1388@2|Bacteria,1TSVC@1239|Firmicutes,248VQ@186801|Clostridia,3XYS2@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3794,LysM
NFNHFNFO_03438	33035.JPJF01000042_gene392	1.29e-64	198.0	2DD3J@1|root,32U0T@2|Bacteria,1VB00@1239|Firmicutes,24N49@186801|Clostridia,3Y0BV@572511|Blautia	186801|Clostridia	S	PrcB C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PrcB_C
NFNHFNFO_03439	33035.JPJF01000042_gene386	8.94e-317	864.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3XZQF@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_03440	33035.JPJF01000042_gene385	2.03e-166	466.0	COG0204@1|root,COG0204@2|Bacteria,1UMJA@1239|Firmicutes,249AV@186801|Clostridia,3XYMN@572511|Blautia	186801|Clostridia	I	Psort location	plsC_1	-	2.3.1.51	ko:K00655	ko00561,ko00564,ko01100,ko01110,map00561,map00564,map01100,map01110	M00089	R02241,R09381	RC00004,RC00037,RC00039	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	Acyltransferase
NFNHFNFO_03441	33035.JPJF01000042_gene384	7.28e-303	828.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYX6@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	mepA_2	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_03442	33035.JPJF01000042_gene383	1.02e-256	712.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,3XZE5@572511|Blautia	186801|Clostridia	S	COG NOG08812 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NFNHFNFO_03443	1235798.C817_03322	1.71e-53	184.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,27VAG@189330|Dorea	186801|Clostridia	S	Predicted AAA-ATPase	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NFNHFNFO_03444	33035.JPJF01000042_gene382	6.07e-59	182.0	COG1343@1|root,COG1343@2|Bacteria,1VAV3@1239|Firmicutes,24NZP@186801|Clostridia,3Y0UB@572511|Blautia	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas2	-	-	ko:K09951	-	-	-	-	ko00000,ko02048	-	-	-	CRISPR_Cas2
NFNHFNFO_03445	553973.CLOHYLEM_05080	8e-194	543.0	COG1518@1|root,COG1518@2|Bacteria,1TQWG@1239|Firmicutes,24889@186801|Clostridia,21YTZ@1506553|Lachnoclostridium	186801|Clostridia	L	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette	cas1	-	-	ko:K15342	-	-	-	-	ko00000,ko02048,ko03400	-	-	-	Cas_Cas1
NFNHFNFO_03446	553973.CLOHYLEM_05081	2.7e-117	340.0	COG1468@1|root,COG1468@2|Bacteria,1TT4D@1239|Firmicutes,24B93@186801|Clostridia,21ZAS@1506553|Lachnoclostridium	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	cas4	-	3.1.12.1	ko:K07464	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Cas_Cas4
NFNHFNFO_03447	411468.CLOSCI_02080	6.19e-157	445.0	COG3649@1|root,COG3649@2|Bacteria,1TQZ8@1239|Firmicutes,248MT@186801|Clostridia,21XMH@1506553|Lachnoclostridium	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K19115,ko:K19118	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas7
NFNHFNFO_03448	411468.CLOSCI_02081	4.15e-253	719.0	COG5632@1|root,COG5632@2|Bacteria,1TR9V@1239|Firmicutes,248QA@186801|Clostridia,2207E@1506553|Lachnoclostridium	186801|Clostridia	M	CRISPR-associated protein (Cas_Csd1)	csd1	-	-	ko:K19117	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Csd1
NFNHFNFO_03449	411468.CLOSCI_02082	1.14e-138	396.0	2DBAF@1|root,2Z82V@2|Bacteria,1TPSR@1239|Firmicutes,24AI1@186801|Clostridia,21ZXQ@1506553|Lachnoclostridium	186801|Clostridia	S	CRISPR-associated protein (Cas_Cas5)	cas5d	-	-	ko:K19119	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas5d
NFNHFNFO_03450	411468.CLOSCI_02083	1.27e-236	689.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,21Z27@1506553|Lachnoclostridium	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	cas3	-	-	ko:K07012	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	DEAD,HD,Helicase_C,ResIII
NFNHFNFO_03451	180332.JTGN01000001_gene5250	0.0	1225.0	COG1196@1|root,COG1196@2|Bacteria,1TR05@1239|Firmicutes,24BXV@186801|Clostridia	186801|Clostridia	D	nuclear chromosome segregation	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03452	180332.JTGN01000001_gene5251	3.73e-114	333.0	28K2I@1|root,2Z9RV@2|Bacteria,1V0BY@1239|Firmicutes,24DD5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03453	180332.JTGN01000001_gene5252	2.3e-215	615.0	28I9Q@1|root,2Z8CD@2|Bacteria,1UQWA@1239|Firmicutes,25D7C@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03454	180332.JTGN01000001_gene5253	1.34e-116	347.0	28M41@1|root,2ZAI3@2|Bacteria,1UZMW@1239|Firmicutes,24ANU@186801|Clostridia	186801|Clostridia	S	Uncharacterized protein conserved in bacteria C-term(DUF2220)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2220
NFNHFNFO_03455	742735.HMPREF9467_01191	1.04e-208	586.0	2EM10@1|root,33EQI@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03456	742735.HMPREF9467_01190	4.85e-193	548.0	COG0468@1|root,COG0468@2|Bacteria,1UJZW@1239|Firmicutes,24DKN@186801|Clostridia	186801|Clostridia	L	P-loop Domain of unknown function (DUF2791)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2791
NFNHFNFO_03457	742735.HMPREF9467_01189	1.32e-118	346.0	28I96@1|root,2Z8BW@2|Bacteria,1UZTH@1239|Firmicutes,24FGR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03458	742735.HMPREF9467_01188	7.45e-159	469.0	COG1061@1|root,COG1061@2|Bacteria,1UIAT@1239|Firmicutes,2498T@186801|Clostridia,223MY@1506553|Lachnoclostridium	186801|Clostridia	L	helicase superfamily c-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	Helicase_C,ResIII
NFNHFNFO_03459	33035.JPJF01000042_gene373	1.94e-24	99.4	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XZ16@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran,TOBE_2
NFNHFNFO_03460	335541.Swol_0734	1.59e-136	390.0	COG1484@1|root,COG1484@2|Bacteria,1TQBX@1239|Firmicutes,249T2@186801|Clostridia	186801|Clostridia	L	ATP-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
NFNHFNFO_03461	33035.JPJF01000074_gene5033	2.37e-62	191.0	COG1358@1|root,COG1358@2|Bacteria,1VEYG@1239|Firmicutes,24QP3@186801|Clostridia,3Y0DE@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Ribosomal_L7Ae
NFNHFNFO_03462	33035.JPJF01000074_gene5034	6.45e-59	182.0	COG2740@1|root,COG2740@2|Bacteria,1VEJS@1239|Firmicutes,24QSJ@186801|Clostridia,3Y0GX@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	ylxR	-	-	ko:K07742	-	-	-	-	ko00000	-	-	-	DUF448
NFNHFNFO_03463	33035.JPJF01000074_gene5035	6.91e-249	687.0	COG0195@1|root,COG0195@2|Bacteria,1TPB3@1239|Firmicutes,247W8@186801|Clostridia,3XZH6@572511|Blautia	186801|Clostridia	K	Participates in both transcription termination and antitermination	nusA	-	-	ko:K02600	-	-	-	-	ko00000,ko03009,ko03021	-	-	-	KH_5,NusA_N,S1
NFNHFNFO_03464	33035.JPJF01000074_gene5036	5.04e-99	288.0	COG0779@1|root,COG0779@2|Bacteria,1V6KT@1239|Firmicutes,24N1G@186801|Clostridia,3Y03N@572511|Blautia	186801|Clostridia	S	Required for maturation of 30S ribosomal subunits	rimP	-	-	ko:K09748	-	-	-	-	ko00000,ko03009	-	-	-	DUF150,DUF150_C
NFNHFNFO_03465	33035.JPJF01000074_gene5037	1.23e-260	718.0	COG5279@1|root,COG5279@2|Bacteria,1TY2Q@1239|Firmicutes,24BDS@186801|Clostridia,3XZN1@572511|Blautia	186801|Clostridia	D	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NFNHFNFO_03466	33035.JPJF01000074_gene5038	3.6e-204	566.0	COG0598@1|root,COG0598@2|Bacteria,1TPSV@1239|Firmicutes,24DE3@186801|Clostridia,3Y009@572511|Blautia	186801|Clostridia	P	Psort location	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
NFNHFNFO_03467	33035.JPJF01000074_gene5039	0.0	1400.0	COG0188@1|root,COG0188@2|Bacteria,1TPNX@1239|Firmicutes,24ADK@186801|Clostridia,3XZJ2@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	gyrA_1	-	5.99.1.3	ko:K02469	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseA_C,DNA_topoisoIV
NFNHFNFO_03468	33035.JPJF01000074_gene5040	0.0	1262.0	COG0187@1|root,COG0187@2|Bacteria,1TRSZ@1239|Firmicutes,247ZY@186801|Clostridia,3XYT8@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	parE	-	5.99.1.3	ko:K02470	-	-	-	-	ko00000,ko01000,ko03032,ko03400	-	-	-	DNA_gyraseB,DNA_gyraseB_C,HATPase_c,Toprim
NFNHFNFO_03469	33035.JPJF01000074_gene5041	1.22e-176	494.0	COG0561@1|root,COG0561@2|Bacteria,1TREF@1239|Firmicutes,25AZZ@186801|Clostridia	186801|Clostridia	S	Hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Hydrolase_3
NFNHFNFO_03470	33035.JPJF01000074_gene5042	3.96e-112	323.0	COG0671@1|root,COG0671@2|Bacteria,1VB7J@1239|Firmicutes,24JDD@186801|Clostridia,3Y0A5@572511|Blautia	186801|Clostridia	I	COG COG0671 Membrane-associated phospholipid phosphatase	bcrC	-	3.6.1.27	ko:K19302	ko00550,map00550	-	R05627	RC00002	ko00000,ko00001,ko01000,ko01011	-	-	-	PAP2
NFNHFNFO_03471	584708.Apau_2287	7.71e-131	387.0	COG0436@1|root,COG0436@2|Bacteria,3TAA9@508458|Synergistetes	508458|Synergistetes	E	PFAM Aminotransferase class I and II	-	-	2.6.1.1	ko:K00812,ko:K10907	ko00220,ko00250,ko00270,ko00330,ko00350,ko00360,ko00400,ko00401,ko00950,ko00960,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map00250,map00270,map00330,map00350,map00360,map00400,map00401,map00950,map00960,map01100,map01110,map01130,map01210,map01230	-	R00355,R00694,R00734,R00896,R02433,R02619,R05052	RC00006	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_1_2
NFNHFNFO_03472	1132509.C447_10545	2.74e-40	147.0	COG1402@1|root,arCOG04536@2157|Archaea,2XWZU@28890|Euryarchaeota,23VFZ@183963|Halobacteria	183963|Halobacteria	H	protein, putative amidase	-	-	3.5.2.10	ko:K01470	ko00330,map00330	-	R01884	RC00615	ko00000,ko00001,ko01000	-	-	-	Creatininase
NFNHFNFO_03473	1235792.C808_04382	3.25e-90	285.0	COG0498@1|root,COG0498@2|Bacteria,1TP25@1239|Firmicutes,25B08@186801|Clostridia	186801|Clostridia	E	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine	thrC	-	4.2.3.1	ko:K01733	ko00260,ko00750,ko01100,ko01110,ko01120,ko01230,map00260,map00750,map01100,map01110,map01120,map01230	M00018	R01466,R05086	RC00017,RC00526	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NFNHFNFO_03474	1121468.AUBR01000060_gene998	5.45e-17	84.7	COG0491@1|root,COG0491@2|Bacteria,1UZUA@1239|Firmicutes,24CIA@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
NFNHFNFO_03475	266117.Rxyl_0346	1.45e-66	214.0	COG1028@1|root,COG1028@2|Bacteria,2GNIN@201174|Actinobacteria,4CT0P@84995|Rubrobacteria	84995|Rubrobacteria	IQ	Short-chain dehydrogenase reductase SDR	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short_C2
NFNHFNFO_03476	1287116.X734_05270	4.56e-134	404.0	COG1012@1|root,COG1012@2|Bacteria,1MU1V@1224|Proteobacteria,2UNVH@28211|Alphaproteobacteria,43N72@69277|Phyllobacteriaceae	28211|Alphaproteobacteria	C	Aldehyde dehydrogenase family	-	-	-	-	-	-	-	-	-	-	-	-	Aldedh
NFNHFNFO_03477	1232443.BAIA02000122_gene1165	9.03e-148	420.0	COG5426@1|root,COG5426@2|Bacteria,1TNZD@1239|Firmicutes,24A2A@186801|Clostridia	186801|Clostridia	S	Putative glutamine amidotransferase	-	-	-	-	-	-	-	-	-	-	-	-	GATase1_like
NFNHFNFO_03478	1005994.GTGU_00987	1.69e-57	199.0	COG0624@1|root,COG0624@2|Bacteria,1MVBR@1224|Proteobacteria,1RZVX@1236|Gammaproteobacteria	1236|Gammaproteobacteria	E	Acetylornithine deacetylase	-	-	3.5.1.16,3.5.1.18	ko:K01438,ko:K01439	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R00669,R02734,R09107	RC00064,RC00090,RC00300	ko00000,ko00001,ko00002,ko01000	-	-	-	M20_dimer,Peptidase_M20,Peptidase_M28
NFNHFNFO_03479	1232443.BAIA02000121_gene2809	4.91e-317	896.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia	186801|Clostridia	G	import. Responsible for energy coupling to the transport system	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,BPD_transp_2
NFNHFNFO_03480	1232443.BAIA02000121_gene2810	1.64e-98	303.0	COG1879@1|root,COG1879@2|Bacteria,1V6PC@1239|Firmicutes,24JZQ@186801|Clostridia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	-	-	-	-	-	-	-	-	-	Peripla_BP_4
NFNHFNFO_03481	1232443.BAIA02000122_gene1164	1.23e-82	260.0	COG1172@1|root,COG1172@2|Bacteria	2|Bacteria	G	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K10440	ko02010,map02010	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	BPD_transp_2
NFNHFNFO_03482	1232443.BAIA02000122_gene1166	3.33e-100	305.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24NIH@186801|Clostridia,269X0@186813|unclassified Clostridiales	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NFNHFNFO_03483	1449126.JQKL01000011_gene3571	1.35e-50	166.0	COG0251@1|root,COG0251@2|Bacteria,1V6G4@1239|Firmicutes,24IS7@186801|Clostridia,26BMX@186813|unclassified Clostridiales	186801|Clostridia	J	YjgF/chorismate_mutase-like, putative endoribonuclease	-	-	-	-	-	-	-	-	-	-	-	-	YjgF_endoribonc
NFNHFNFO_03484	411902.CLOBOL_00261	5.7e-78	240.0	COG2964@1|root,COG2964@2|Bacteria,1TSI2@1239|Firmicutes,249X6@186801|Clostridia,220E5@1506553|Lachnoclostridium	186801|Clostridia	S	YheO-like PAS domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
NFNHFNFO_03485	33035.JPJF01000074_gene5044	2.32e-169	476.0	COG2162@1|root,COG2162@2|Bacteria,1V2RN@1239|Firmicutes,25DSA@186801|Clostridia	186801|Clostridia	Q	N-acetyltransferase	-	-	2.3.1.118	ko:K00675	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_2
NFNHFNFO_03486	33035.JPJF01000074_gene5045	2.05e-305	837.0	COG2211@1|root,COG2211@2|Bacteria,1UJ7Q@1239|Firmicutes,24DJ1@186801|Clostridia	186801|Clostridia	G	TIGRFAM sugar (Glycoside-Pentoside-Hexuronide) transporter	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_03487	33035.JPJF01000074_gene5046	3.55e-257	704.0	COG0407@1|root,COG0407@2|Bacteria,1V5ND@1239|Firmicutes,24IEP@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_03488	33035.JPJF01000074_gene5047	9.52e-240	659.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia	186801|Clostridia	H	PFAM Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_03489	33035.JPJF01000074_gene5048	0.0	900.0	COG2508@1|root,COG2508@2|Bacteria,1VIT3@1239|Firmicutes,24JXW@186801|Clostridia,3Y0T9@572511|Blautia	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NFNHFNFO_03490	33035.JPJF01000074_gene5049	1.45e-280	772.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3XYNC@572511|Blautia	186801|Clostridia	V	Polysaccharide biosynthesis C-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_03491	33035.JPJF01000041_gene360	1.5e-150	429.0	COG0613@1|root,COG0613@2|Bacteria,1TPI5@1239|Firmicutes,248H2@186801|Clostridia,3XZBW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	3.1.3.97	ko:K07053	-	-	R00188,R11188	RC00078	ko00000,ko01000	-	-	-	PHP
NFNHFNFO_03492	33035.JPJF01000156_gene1234	2.23e-126	363.0	COG5464@1|root,COG5464@2|Bacteria,1TYQI@1239|Firmicutes,24D7J@186801|Clostridia,3Y26P@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
NFNHFNFO_03495	33035.JPJF01000031_gene2332	0.0	1068.0	COG0823@1|root,COG1506@1|root,COG0823@2|Bacteria,COG1506@2|Bacteria,1TQ85@1239|Firmicutes,25B1P@186801|Clostridia	186801|Clostridia	E	Prolyl oligopeptidase family	-	-	-	-	-	-	-	-	-	-	-	-	PD40,Peptidase_S9
NFNHFNFO_03496	33035.JPJF01000031_gene2331	1.02e-282	776.0	COG4565@1|root,COG4565@2|Bacteria,1V17X@1239|Firmicutes,24DMG@186801|Clostridia	186801|Clostridia	KT	transcriptional regulatory protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03497	33035.JPJF01000031_gene2330	9.04e-259	712.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,3Y0FD@572511|Blautia	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
NFNHFNFO_03498	33035.JPJF01000031_gene2329	1.03e-150	427.0	28N4D@1|root,2ZB9V@2|Bacteria,1UPRR@1239|Firmicutes,24MJV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03499	33035.JPJF01000031_gene2328	2.7e-147	417.0	2DMDC@1|root,32PHK@2|Bacteria,1V728@1239|Firmicutes,24K2A@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF5058)	-	-	-	-	-	-	-	-	-	-	-	-	DUF5058
NFNHFNFO_03500	33035.JPJF01000031_gene2327	4.81e-214	592.0	COG2066@1|root,COG2066@2|Bacteria,1TP64@1239|Firmicutes,2491K@186801|Clostridia,3Y153@572511|Blautia	186801|Clostridia	E	Glutaminase	glsA	-	3.5.1.2	ko:K01425	ko00220,ko00250,ko00471,ko01100,ko04724,ko04727,ko04964,ko05206,ko05230,map00220,map00250,map00471,map01100,map04724,map04727,map04964,map05206,map05230	-	R00256,R01579	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Glutaminase
NFNHFNFO_03501	33035.JPJF01000031_gene2326	1.05e-201	560.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3Y16Y@572511|Blautia	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
NFNHFNFO_03502	33035.JPJF01000031_gene2325	6.15e-69	208.0	COG3118@1|root,COG3118@2|Bacteria,1VDSC@1239|Firmicutes,25N64@186801|Clostridia,3Y27F@572511|Blautia	186801|Clostridia	O	Thioredoxin	-	-	-	-	-	-	-	-	-	-	-	-	Thioredoxin
NFNHFNFO_03503	33035.JPJF01000031_gene2324	0.0	895.0	COG2986@1|root,COG2986@2|Bacteria,1TQ8I@1239|Firmicutes,24E1T@186801|Clostridia	186801|Clostridia	E	Aromatic amino acid lyase	-	-	-	-	-	-	-	-	-	-	-	-	Lyase_aromatic
NFNHFNFO_03504	33035.JPJF01000031_gene2323	6.37e-234	645.0	COG2055@1|root,COG2055@2|Bacteria,1TR0Z@1239|Firmicutes,247W5@186801|Clostridia,3Y0AK@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	dlgD	-	1.1.1.130	ko:K08092	ko00040,ko00053,map00040,map00053	-	R02637,R02639	RC00238	ko00000,ko00001,ko01000	-	-	-	Ldh_2
NFNHFNFO_03505	33035.JPJF01000031_gene2322	0.0	883.0	COG5598@1|root,COG5598@2|Bacteria,1V5NM@1239|Firmicutes,25AYD@186801|Clostridia	186801|Clostridia	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
NFNHFNFO_03506	33035.JPJF01000031_gene2321	1.51e-91	268.0	COG1786@1|root,COG1786@2|Bacteria,1V9ZT@1239|Firmicutes,24N2I@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
NFNHFNFO_03507	33035.JPJF01000031_gene2320	8.71e-312	849.0	COG1679@1|root,COG1679@2|Bacteria,1UJDG@1239|Firmicutes,24DTH@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
NFNHFNFO_03508	33035.JPJF01000031_gene2319	1.49e-87	258.0	COG1786@1|root,COG1786@2|Bacteria,1V4V4@1239|Firmicutes,24I6P@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
NFNHFNFO_03509	33035.JPJF01000031_gene2318	3.5e-291	795.0	COG1679@1|root,COG1679@2|Bacteria,1UJDG@1239|Firmicutes,24DTH@186801|Clostridia,3Y1UT@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
NFNHFNFO_03510	33035.JPJF01000031_gene2317	0.0	895.0	COG2986@1|root,COG2986@2|Bacteria,1TQ8I@1239|Firmicutes,24E1T@186801|Clostridia,3Y0YT@572511|Blautia	186801|Clostridia	E	Aromatic amino acid lyase	-	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
NFNHFNFO_03511	33035.JPJF01000031_gene2316	4.76e-109	315.0	2EATI@1|root,334VA@2|Bacteria,1VFEE@1239|Firmicutes,24QRH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03512	1121296.JONJ01000012_gene407	9.97e-20	89.7	COG0591@1|root,COG0591@2|Bacteria,1V0NB@1239|Firmicutes,24ENM@186801|Clostridia	186801|Clostridia	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
NFNHFNFO_03513	33035.JPJF01000031_gene2314	1.32e-315	862.0	COG0591@1|root,COG0591@2|Bacteria,1V0NB@1239|Firmicutes,24ENM@186801|Clostridia	186801|Clostridia	E	Sodium:solute symporter family	-	-	-	ko:K03307	-	-	-	-	ko00000	2.A.21	-	-	SSF
NFNHFNFO_03514	33035.JPJF01000031_gene2313	0.0	874.0	COG5598@1|root,COG5598@2|Bacteria,1V5NM@1239|Firmicutes,25AYD@186801|Clostridia	186801|Clostridia	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
NFNHFNFO_03515	33035.JPJF01000031_gene2312	1.12e-82	246.0	COG0251@1|root,COG0251@2|Bacteria,1TTHQ@1239|Firmicutes,254ZB@186801|Clostridia	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
NFNHFNFO_03516	33035.JPJF01000031_gene2311	0.0	1710.0	COG3629@1|root,COG3899@1|root,COG3629@2|Bacteria,COG3899@2|Bacteria,1TR6V@1239|Firmicutes,24AA2@186801|Clostridia	186801|Clostridia	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_16,BTAD,TPR_12,Trans_reg_C
NFNHFNFO_03517	33035.JPJF01000031_gene2310	2.74e-218	603.0	COG1143@1|root,COG1143@2|Bacteria,1UI0U@1239|Firmicutes,25E9M@186801|Clostridia	186801|Clostridia	C	PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
NFNHFNFO_03518	33035.JPJF01000031_gene2309	0.0	969.0	COG1115@1|root,COG1115@2|Bacteria,1TNZP@1239|Firmicutes,247S6@186801|Clostridia,3XZ7T@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Na_Ala_symp
NFNHFNFO_03520	33035.JPJF01000031_gene2300	2.01e-184	514.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia,3Y0FC@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_03521	33035.JPJF01000031_gene2299	5.26e-209	578.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia	186801|Clostridia	P	Abc transporter, permease protein	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_03522	33035.JPJF01000031_gene2298	3.88e-310	846.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,248X0@186801|Clostridia	186801|Clostridia	G	solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_03523	33035.JPJF01000031_gene2297	1.42e-213	589.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,3XZEN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_03524	33035.JPJF01000016_gene4013	8.4e-148	420.0	COG1277@1|root,COG1277@2|Bacteria,1UYUR@1239|Firmicutes,24HPX@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
NFNHFNFO_03525	33035.JPJF01000016_gene4012	6.73e-192	535.0	COG1131@1|root,COG1131@2|Bacteria,1TQEV@1239|Firmicutes,25B0Q@186801|Clostridia,3Y1FQ@572511|Blautia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
NFNHFNFO_03526	33035.JPJF01000016_gene4011	4.29e-32	112.0	2E3AZ@1|root,32YAF@2|Bacteria,1VF37@1239|Firmicutes,24R3T@186801|Clostridia	186801|Clostridia	S	Phospholipase_D-nuclease N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	PLDc_N
NFNHFNFO_03527	33035.JPJF01000016_gene4010	3.83e-201	565.0	COG1476@1|root,COG1476@2|Bacteria,1TNYC@1239|Firmicutes,248I9@186801|Clostridia,3Y1WY@572511|Blautia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_03528	33035.JPJF01000016_gene4009	2.43e-108	319.0	2DVAH@1|root,32UZ0@2|Bacteria,1VMS9@1239|Firmicutes,24IP4@186801|Clostridia,3Y09C@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DUF3784
NFNHFNFO_03529	33035.JPJF01000016_gene4008	6.02e-191	532.0	COG0583@1|root,COG0583@2|Bacteria,1U2EY@1239|Firmicutes,24DBM@186801|Clostridia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_03530	33035.JPJF01000016_gene4007	0.0	1275.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3XZ6J@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	enr	-	1.3.1.31	ko:K10797	ko00360,ko01120,map00360,map01120	-	R02252	RC00669	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
NFNHFNFO_03531	33035.JPJF01000016_gene4006	4.54e-225	622.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XZP5@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NFNHFNFO_03532	33035.JPJF01000016_gene4005	9.56e-178	497.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZFZ@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
NFNHFNFO_03533	33035.JPJF01000016_gene4004	0.0	1015.0	COG0747@1|root,COG0747@2|Bacteria,1TQ0N@1239|Firmicutes,25CDM@186801|Clostridia,3XYJX@572511|Blautia	186801|Clostridia	E	Bacterial extracellular solute-binding proteins, family 5 Middle	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NFNHFNFO_03534	33035.JPJF01000016_gene4003	0.0	960.0	COG1123@1|root,COG4172@2|Bacteria,1UZK8@1239|Firmicutes,2511Z@186801|Clostridia,3XZHB@572511|Blautia	186801|Clostridia	P	COG COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran,oligo_HPY
NFNHFNFO_03535	33035.JPJF01000016_gene4002	2.44e-153	434.0	COG2755@1|root,COG2755@2|Bacteria,1VAV9@1239|Firmicutes,25B1C@186801|Clostridia,3Y0ES@572511|Blautia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NFNHFNFO_03536	33035.JPJF01000016_gene4001	4.37e-85	253.0	2DNPY@1|root,32YIB@2|Bacteria,1VHHM@1239|Firmicutes,24U1K@186801|Clostridia,3Y2D1@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4358)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4358
NFNHFNFO_03537	33035.JPJF01000016_gene4000	1.32e-294	808.0	COG1696@1|root,COG1696@2|Bacteria,1TP52@1239|Firmicutes,248V4@186801|Clostridia,3XYV7@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score 9.99	algI	-	-	ko:K19294	-	-	-	-	ko00000	-	-	-	MBOAT
NFNHFNFO_03538	33035.JPJF01000016_gene3999	1.34e-242	671.0	28IAA@1|root,2Z8CW@2|Bacteria,1TQHP@1239|Firmicutes,248TG@186801|Clostridia,3XZ6I@572511|Blautia	186801|Clostridia	S	DHHW protein	-	-	-	-	-	-	-	-	-	-	-	-	DHHW
NFNHFNFO_03539	33035.JPJF01000016_gene3998	3.42e-107	310.0	COG0440@1|root,COG0440@2|Bacteria,1V2AJ@1239|Firmicutes,24HZM@186801|Clostridia,3Y022@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ilvN	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS10025	ACT,ACT_5,ALS_ss_C
NFNHFNFO_03540	33035.JPJF01000016_gene3997	3.6e-242	665.0	COG0059@1|root,COG0059@2|Bacteria,1TPI7@1239|Firmicutes,247RH@186801|Clostridia,3XYWE@572511|Blautia	186801|Clostridia	H	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate	ilvC	-	1.1.1.86	ko:K00053	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R03051,R04439,R04440,R05068,R05069,R05071	RC00726,RC00836,RC00837,RC01726	ko00000,ko00001,ko00002,ko01000	-	-	-	IlvC,IlvN
NFNHFNFO_03541	33035.JPJF01000016_gene3996	3.09e-212	586.0	COG0583@1|root,COG0583@2|Bacteria,1TR84@1239|Firmicutes,24BU7@186801|Clostridia,3XZQ2@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_03542	33035.JPJF01000016_gene3995	1.85e-303	827.0	COG0065@1|root,COG0065@2|Bacteria,1TPE5@1239|Firmicutes,2484F@186801|Clostridia,3XYP1@572511|Blautia	186801|Clostridia	H	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuC	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01703,ko:K20452	ko00290,ko00660,ko00760,ko00966,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map00966,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R08620,R08624,R08628,R08634,R08641,R08645,R10170	RC00497,RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS04465	Aconitase
NFNHFNFO_03543	33035.JPJF01000016_gene3994	1.49e-113	325.0	COG0066@1|root,COG0066@2|Bacteria,1V1I6@1239|Firmicutes,24FUI@186801|Clostridia,3XZW2@572511|Blautia	186801|Clostridia	E	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate	leuD	-	4.2.1.33,4.2.1.35,4.2.1.85	ko:K01704,ko:K20453	ko00290,ko00660,ko00760,ko01100,ko01110,ko01120,ko01210,ko01230,map00290,map00660,map00760,map01100,map01110,map01120,map01210,map01230	M00432,M00535	R03069,R03896,R03898,R03968,R04001,R10170	RC00843,RC00976,RC00977,RC01041,RC01046,RC03072	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase_C
NFNHFNFO_03544	33035.JPJF01000016_gene3993	4.86e-46	152.0	COG1051@1|root,COG1051@2|Bacteria,1VH0H@1239|Firmicutes,24Q66@186801|Clostridia	186801|Clostridia	F	NUDIX domain	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX
NFNHFNFO_03545	33035.JPJF01000025_gene2627	1.2e-32	116.0	COG2201@1|root,COG2201@2|Bacteria	2|Bacteria	NT	protein-glutamate methylesterase activity	-	-	3.1.1.61,3.5.1.44	ko:K02282,ko:K03412,ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035,ko02044	-	-	-	CheB_methylest,Response_reg,Spo0A_C
NFNHFNFO_03546	1280676.AUJO01000027_gene3072	1.18e-290	803.0	COG4584@1|root,COG4584@2|Bacteria,1TR5X@1239|Firmicutes,249QR@186801|Clostridia,4BY3X@830|Butyrivibrio	186801|Clostridia	L	PFAM integrase	-	-	-	-	-	-	-	-	-	-	-	-	rve
NFNHFNFO_03547	1280676.AUJO01000027_gene3071	4.59e-156	441.0	COG1484@1|root,COG1484@2|Bacteria,1TRNX@1239|Firmicutes,24EVP@186801|Clostridia,4BZPJ@830|Butyrivibrio	186801|Clostridia	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21
NFNHFNFO_03548	411474.COPEUT_01800	5.06e-27	104.0	COG1695@1|root,COG1695@2|Bacteria,1VHJD@1239|Firmicutes,24QBN@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, PadR family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
NFNHFNFO_03551	411468.CLOSCI_03516	3.44e-101	299.0	COG4461@1|root,COG4461@2|Bacteria,1VDVF@1239|Firmicutes,24N0M@186801|Clostridia,21ZZE@1506553|Lachnoclostridium	186801|Clostridia	S	Domain of unknown function (DUF4163)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3298,DUF4163
NFNHFNFO_03552	33035.JPJF01000016_gene3990	4.53e-82	245.0	COG3476@1|root,COG3476@2|Bacteria,1V896@1239|Firmicutes,24MTF@186801|Clostridia,3Y0FN@572511|Blautia	186801|Clostridia	T	TspO/MBR family	-	-	-	ko:K05770	ko04080,ko04214,ko04979,ko05166,map04080,map04214,map04979,map05166	-	-	-	ko00000,ko00001,ko02000	9.A.24	-	-	TspO_MBR
NFNHFNFO_03554	573413.Spirs_3380	5.02e-82	259.0	COG0407@1|root,COG0407@2|Bacteria,2JAKX@203691|Spirochaetes	203691|Spirochaetes	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	URO-D
NFNHFNFO_03557	500632.CLONEX_04135	2.02e-131	381.0	COG0582@1|root,COG0582@2|Bacteria,1TPCB@1239|Firmicutes,2485Y@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Integrase_DNA,Phage_int_SAM_5,Phage_integrase
NFNHFNFO_03558	33035.JPJF01000062_gene3655	1.22e-59	192.0	COG5464@1|root,COG5464@2|Bacteria,1TPB1@1239|Firmicutes,24B0D@186801|Clostridia,3Y1C0@572511|Blautia	186801|Clostridia	S	COG NOG17660 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NFNHFNFO_03559	33035.JPJF01000062_gene3655	4.15e-77	238.0	COG5464@1|root,COG5464@2|Bacteria,1TPB1@1239|Firmicutes,24B0D@186801|Clostridia,3Y1C0@572511|Blautia	186801|Clostridia	S	COG NOG17660 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NFNHFNFO_03560	33035.JPJF01000062_gene3655	1.88e-166	470.0	COG5464@1|root,COG5464@2|Bacteria,1TPB1@1239|Firmicutes,24B0D@186801|Clostridia,3Y1C0@572511|Blautia	186801|Clostridia	S	COG NOG17660 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	PDDEXK_2
NFNHFNFO_03561	33035.JPJF01000062_gene3653	2.09e-45	146.0	COG1925@1|root,COG1925@2|Bacteria,1URTV@1239|Firmicutes,259R8@186801|Clostridia,3Y261@572511|Blautia	186801|Clostridia	G	phosphoenolpyruvate-dependent sugar phosphotransferase system	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03562	33035.JPJF01000062_gene3646	1.62e-81	242.0	2D5AS@1|root,32TIN@2|Bacteria,1VA4E@1239|Firmicutes,24JJQ@186801|Clostridia,3Y1UV@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	Cytochrom_B561
NFNHFNFO_03563	33035.JPJF01000062_gene3644	0.0	1291.0	COG0073@1|root,COG0143@1|root,COG0073@2|Bacteria,COG0143@2|Bacteria,1TPA1@1239|Firmicutes,248AU@186801|Clostridia,3XYH1@572511|Blautia	186801|Clostridia	J	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation	metG	-	6.1.1.10	ko:K01874	ko00450,ko00970,map00450,map00970	M00359,M00360	R03659,R04773	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1g,tRNA_bind
NFNHFNFO_03564	33035.JPJF01000062_gene3636	9.44e-192	533.0	COG2207@1|root,COG2207@2|Bacteria,1TR2K@1239|Firmicutes,24ABH@186801|Clostridia,3Y03Y@572511|Blautia	186801|Clostridia	K	AraC-like ligand binding domain	araC_2	-	-	ko:K02099	-	-	-	-	ko00000,ko03000	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_03565	33035.JPJF01000062_gene3635	0.0	2057.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3XYIU@572511|Blautia	186801|Clostridia	G	Beta galactosidase small chain	-	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFNHFNFO_03566	33035.JPJF01000062_gene3634	2.67e-170	478.0	COG2365@1|root,COG2365@2|Bacteria,1V851@1239|Firmicutes,24GVA@186801|Clostridia,3XZNA@572511|Blautia	186801|Clostridia	T	Tyrosine phosphatase family	-	-	-	-	-	-	-	-	-	-	-	-	Y_phosphatase3
NFNHFNFO_03567	33035.JPJF01000062_gene3632	1.45e-122	351.0	COG0110@1|root,COG0110@2|Bacteria,1TQEX@1239|Firmicutes,249KF@186801|Clostridia,3XZYR@572511|Blautia	186801|Clostridia	S	Maltose acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Hexapep,Hexapep_2,Mac
NFNHFNFO_03568	33035.JPJF01000062_gene3631	0.0	1581.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3XZ58@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase,Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
NFNHFNFO_03569	33035.JPJF01000062_gene3630	8.01e-220	612.0	COG0628@1|root,COG0628@2|Bacteria,1TQBF@1239|Firmicutes,25CCK@186801|Clostridia,3XYVI@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NFNHFNFO_03570	33035.JPJF01000062_gene3629	5.18e-173	483.0	COG0084@1|root,COG0084@2|Bacteria,1TNY1@1239|Firmicutes,248HE@186801|Clostridia,3XZFC@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	ycfH	-	-	ko:K03424	-	-	-	-	ko00000,ko01000	-	-	-	TatD_DNase
NFNHFNFO_03571	33035.JPJF01000062_gene3628	1.09e-132	377.0	COG1309@1|root,COG1309@2|Bacteria,1V5H6@1239|Firmicutes,24ITS@186801|Clostridia,3Y1HI@572511|Blautia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_03572	33035.JPJF01000062_gene3627	0.0	903.0	COG0366@1|root,COG0366@2|Bacteria,1TQFJ@1239|Firmicutes,249Y3@186801|Clostridia,3XZH5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.2.1.133,3.2.1.135,3.2.1.54,3.5.4.33	ko:K01208,ko:K11991	ko00500,ko01100,map00500,map01100	-	R02112,R03122,R10223,R11262	RC00477	ko00000,ko00001,ko01000,ko03016	-	GH13	-	Alpha-amylase,Alpha-amylase_C,DUF1653,Malt_amylase_C
NFNHFNFO_03573	33035.JPJF01000062_gene3626	0.0	1300.0	COG0296@1|root,COG0296@2|Bacteria,1TP4M@1239|Firmicutes,247WH@186801|Clostridia,3XYYD@572511|Blautia	186801|Clostridia	G	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position	glgB	-	2.4.1.18	ko:K00700	ko00500,ko01100,ko01110,map00500,map01100,map01110	M00565	R02110	-	ko00000,ko00001,ko00002,ko01000,ko04147	-	CBM48,GH13	-	Alpha-amylase,Alpha-amylase_C,CBM_48
NFNHFNFO_03574	33035.JPJF01000062_gene3625	9.14e-195	545.0	COG2355@1|root,COG2355@2|Bacteria,1UA7M@1239|Firmicutes,24AE6@186801|Clostridia,3Y005@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	3.4.13.19	ko:K01273	-	-	-	-	ko00000,ko00537,ko01000,ko01002,ko04147	-	-	-	Peptidase_M19
NFNHFNFO_03575	33035.JPJF01000062_gene3624	6.02e-87	261.0	COG0352@1|root,COG0352@2|Bacteria,1V4SE@1239|Firmicutes,24JTR@186801|Clostridia,3Y00P@572511|Blautia	186801|Clostridia	H	Thiamine monophosphate synthase	tenI	-	2.5.1.3	ko:K00788	ko00730,ko01100,map00730,map01100	M00127	R03223,R10712	RC00224,RC03255,RC03397	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS06600	TMP-TENI
NFNHFNFO_03576	33035.JPJF01000062_gene3623	5.2e-251	691.0	COG0502@1|root,COG0502@2|Bacteria,1TPEX@1239|Firmicutes,248PF@186801|Clostridia,3XYRP@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	thiH	-	4.1.99.19	ko:K03150	ko00730,ko01100,map00730,map01100	-	R10246	RC01434,RC03095	ko00000,ko00001,ko01000	-	-	-	BATS,Radical_SAM
NFNHFNFO_03577	33035.JPJF01000062_gene3622	1.99e-164	462.0	COG2022@1|root,COG2022@2|Bacteria,1TQZ1@1239|Firmicutes,247TJ@186801|Clostridia,3XZG0@572511|Blautia	186801|Clostridia	H	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S	thiG	-	2.8.1.10	ko:K03149	ko00730,ko01100,map00730,map01100	-	R10247	RC03096,RC03097,RC03461	ko00000,ko00001,ko01000	-	-	-	ThiG
NFNHFNFO_03578	33035.JPJF01000062_gene3621	3.04e-128	367.0	COG0476@1|root,COG0476@2|Bacteria,1UYFC@1239|Firmicutes,247UZ@186801|Clostridia,3Y1J5@572511|Blautia	186801|Clostridia	H	ThiF family	thiF	-	2.7.7.73	ko:K03148	ko00730,ko01100,ko04122,map00730,map01100,map04122	-	R07459	RC00043	ko00000,ko00001,ko01000	-	-	-	ThiF,ThiS-like
NFNHFNFO_03579	33035.JPJF01000062_gene3620	9.12e-29	103.0	COG2104@1|root,COG2104@2|Bacteria,1VKB4@1239|Firmicutes,25HV0@186801|Clostridia,3Y0TI@572511|Blautia	186801|Clostridia	H	ThiS family	-	-	-	ko:K03154	ko04122,map04122	-	-	-	ko00000,ko00001	-	-	-	ThiS
NFNHFNFO_03580	33035.JPJF01000062_gene3619	1.34e-314	857.0	COG0422@1|root,COG0422@2|Bacteria,1TNZ3@1239|Firmicutes,247JE@186801|Clostridia,3XZM9@572511|Blautia	186801|Clostridia	H	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction	thiC	-	4.1.99.17	ko:K03147	ko00730,ko01100,map00730,map01100	M00127	R03472	RC03251,RC03252	ko00000,ko00001,ko00002,ko01000	-	-	-	ThiC_Rad_SAM
NFNHFNFO_03581	33035.JPJF01000062_gene3618	0.0	1338.0	COG1501@1|root,COG1501@2|Bacteria,1TR8N@1239|Firmicutes,248WR@186801|Clostridia,3Y2CQ@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 31	-	-	3.2.1.177	ko:K01811	-	-	-	-	ko00000,ko01000	-	GH31	-	DUF4968,DUF5110,Glyco_hydro_31
NFNHFNFO_03582	33035.JPJF01000062_gene3617	4.28e-181	507.0	COG2207@1|root,COG2207@2|Bacteria,1TSRS@1239|Firmicutes,24I3P@186801|Clostridia,3Y1VY@572511|Blautia	186801|Clostridia	K	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_03583	33035.JPJF01000062_gene3616	3.87e-249	684.0	COG2008@1|root,COG2008@2|Bacteria,1TPZI@1239|Firmicutes,248TR@186801|Clostridia,3XZ15@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	ltaE	-	4.1.2.48	ko:K01620	ko00260,ko01100,ko01110,ko01120,ko01130,ko01230,map00260,map01100,map01110,map01120,map01130,map01230	-	R00751,R06171	RC00312,RC00372	ko00000,ko00001,ko01000	-	-	-	Beta_elim_lyase
NFNHFNFO_03584	33035.JPJF01000062_gene3614	6.01e-236	653.0	COG0789@1|root,COG0789@2|Bacteria,1V12J@1239|Firmicutes,24DI4@186801|Clostridia	186801|Clostridia	K	regulatory protein MerR	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,Methyltransf_25,Methyltransf_31
NFNHFNFO_03585	33035.JPJF01000062_gene3613	4.32e-278	763.0	COG0141@1|root,COG0141@2|Bacteria,1TPAW@1239|Firmicutes,248X8@186801|Clostridia,3XZ14@572511|Blautia	186801|Clostridia	E	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine	hisD	-	1.1.1.23,1.1.1.308	ko:K00013,ko:K15509	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01158,R01163,R03012	RC00099,RC00242,RC00463	ko00000,ko00001,ko00002,ko01000	-	-	-	Aminotran_1_2,Histidinol_dh
NFNHFNFO_03586	33035.JPJF01000062_gene3612	6.51e-194	540.0	COG2421@1|root,COG2421@2|Bacteria,1TQ67@1239|Firmicutes,24ZE8@186801|Clostridia,3Y1PE@572511|Blautia	186801|Clostridia	C	Acetamidase/Formamidase family	-	-	-	-	-	-	-	-	-	-	-	-	FmdA_AmdA
NFNHFNFO_03587	33035.JPJF01000062_gene3611	0.0	902.0	COG1757@1|root,COG1757@2|Bacteria,1TQ3B@1239|Firmicutes,248WN@186801|Clostridia,3Y0D2@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	nhaC	-	-	ko:K03315	-	-	-	-	ko00000,ko02000	2.A.35	-	-	Na_H_antiporter
NFNHFNFO_03588	1226325.HMPREF1548_04051	7.5e-87	263.0	COG0745@1|root,COG0745@2|Bacteria,1V1ZV@1239|Firmicutes,24GM1@186801|Clostridia,36IMV@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_03589	556261.HMPREF0240_02302	9.11e-112	332.0	COG0642@1|root,COG2205@2|Bacteria,1TT7F@1239|Firmicutes,247UJ@186801|Clostridia,36W9P@31979|Clostridiaceae	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_03590	411470.RUMGNA_03563	2.23e-121	351.0	COG1136@1|root,COG1136@2|Bacteria,1UUUX@1239|Firmicutes,25KAJ@186801|Clostridia,3Y12W@572511|Blautia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_03591	180332.JTGN01000002_gene5639	3.25e-247	721.0	COG0577@1|root,COG0577@2|Bacteria,1TV1M@1239|Firmicutes,24E2X@186801|Clostridia	186801|Clostridia	V	Efflux ABC transporter, permease protein	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NFNHFNFO_03592	537007.BLAHAN_07064	1.02e-174	498.0	COG0523@1|root,COG0523@2|Bacteria,1TPCG@1239|Firmicutes,248XD@186801|Clostridia,3XYNY@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	cobW	-	-	-	-	-	-	-	-	-	-	-	CobW_C,cobW
NFNHFNFO_03593	33035.JPJF01000147_gene1789	1.13e-223	617.0	COG0523@1|root,COG3689@1|root,COG0523@2|Bacteria,COG3689@2|Bacteria,1TS8P@1239|Firmicutes,248DY@186801|Clostridia,3XZGD@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	cobW
NFNHFNFO_03594	33035.JPJF01000147_gene1790	1.26e-130	371.0	COG0193@1|root,COG0193@2|Bacteria,1V3NB@1239|Firmicutes,24HMC@186801|Clostridia,3XYSI@572511|Blautia	186801|Clostridia	J	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis	pth	-	3.1.1.29	ko:K01056	-	-	-	-	ko00000,ko01000,ko03012	-	-	-	Pept_tRNA_hydro
NFNHFNFO_03595	33035.JPJF01000147_gene1791	0.0	2202.0	COG1197@1|root,COG1197@2|Bacteria,1TPF1@1239|Firmicutes,248D8@186801|Clostridia,3XZME@572511|Blautia	186801|Clostridia	L	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site	mfd	-	-	ko:K03723	ko03420,map03420	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	CarD_CdnL_TRCF,DEAD,Helicase_C,TRCF
NFNHFNFO_03596	33035.JPJF01000147_gene1792	1.39e-211	592.0	COG0760@1|root,COG0760@2|Bacteria,1V1WU@1239|Firmicutes,24G3V@186801|Clostridia,3Y03A@572511|Blautia	186801|Clostridia	O	PPIC-type PPIASE domain	-	-	5.2.1.8	ko:K07533	-	-	-	-	ko00000,ko01000,ko03110	-	-	-	Rotamase,Rotamase_2,SurA_N_3
NFNHFNFO_03597	33035.JPJF01000044_gene1072	6.89e-168	474.0	COG0583@1|root,COG0583@2|Bacteria,1TP6T@1239|Firmicutes,24970@186801|Clostridia,3Y0C6@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_03598	33035.JPJF01000044_gene1073	8.87e-107	311.0	COG2059@1|root,COG2059@2|Bacteria,1V22C@1239|Firmicutes,24G7P@186801|Clostridia,3XZU9@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
NFNHFNFO_03599	33035.JPJF01000044_gene1074	2.24e-113	327.0	COG2059@1|root,COG2059@2|Bacteria,1V42U@1239|Firmicutes,24HA0@186801|Clostridia,3XZUW@572511|Blautia	186801|Clostridia	P	Chromate transporter	-	-	-	ko:K07240	-	-	-	-	ko00000,ko02000	2.A.51.1	-	-	Chromate_transp
NFNHFNFO_03600	33035.JPJF01000044_gene1075	5.86e-189	525.0	COG2207@1|root,COG2207@2|Bacteria,1V59G@1239|Firmicutes,24KRI@186801|Clostridia,3Y26X@572511|Blautia	186801|Clostridia	K	Sensory domain found in PocR	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,PocR
NFNHFNFO_03601	33035.JPJF01000044_gene1076	5.32e-249	685.0	COG2334@1|root,COG2334@2|Bacteria,1UXS1@1239|Firmicutes,25MC4@186801|Clostridia,3XZ7J@572511|Blautia	2|Bacteria	M	Psort location Cytoplasmic, score 8.87	mdsC	-	2.7.1.162,2.7.1.39	ko:K02204,ko:K13059	ko00260,ko01100,ko01110,ko01120,ko01230,map00260,map01100,map01110,map01120,map01230	M00018	R01771,R08962	RC00002,RC00017,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	APH
NFNHFNFO_03602	33035.JPJF01000044_gene1077	3.71e-208	577.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
NFNHFNFO_03603	33035.JPJF01000044_gene1078	6.73e-303	828.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,249Q3@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_03604	33035.JPJF01000044_gene1079	1.39e-106	308.0	COG0700@1|root,COG0700@2|Bacteria,1V45M@1239|Firmicutes,24HSJ@186801|Clostridia,3Y01E@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	spmB	-	-	ko:K06374	-	-	-	-	ko00000	-	-	-	Gate
NFNHFNFO_03605	33035.JPJF01000044_gene1080	0.0	1120.0	COG0642@1|root,COG0642@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,3Y28B@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg,SBP_bac_3
NFNHFNFO_03606	33035.JPJF01000044_gene1081	1.98e-287	785.0	COG3705@1|root,COG3705@2|Bacteria,1TPZZ@1239|Firmicutes,248CB@186801|Clostridia,3XYWI@572511|Blautia	186801|Clostridia	E	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine	hisZ	-	-	ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002	-	-	-	tRNA-synt_His
NFNHFNFO_03607	33035.JPJF01000044_gene1082	8.65e-144	406.0	COG0040@1|root,COG0040@2|Bacteria,1TSVZ@1239|Firmicutes,249AR@186801|Clostridia,3XZ1U@572511|Blautia	186801|Clostridia	H	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity	hisG	-	2.4.2.17	ko:K00765,ko:K02502	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R01071	RC02819,RC03200	ko00000,ko00001,ko00002,ko01000	-	-	-	HisG
NFNHFNFO_03608	33035.JPJF01000044_gene1083	1.68e-231	639.0	COG0079@1|root,COG0079@2|Bacteria,1TPUV@1239|Firmicutes,24837@186801|Clostridia,3XYHE@572511|Blautia	186801|Clostridia	E	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily	hisC	GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769	2.6.1.9	ko:K00817	ko00340,ko00350,ko00360,ko00400,ko00401,ko00960,ko01100,ko01110,ko01130,ko01230,map00340,map00350,map00360,map00400,map00401,map00960,map01100,map01110,map01130,map01230	M00026	R00694,R00734,R03243	RC00006,RC00888	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NFNHFNFO_03609	33035.JPJF01000044_gene1084	2.75e-131	373.0	COG0131@1|root,COG0131@2|Bacteria,1TRH7@1239|Firmicutes,247WC@186801|Clostridia,3XYJ4@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisB	-	4.2.1.19	ko:K01693	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R03457	RC00932	ko00000,ko00001,ko00002,ko01000	-	-	-	IGPD
NFNHFNFO_03610	33035.JPJF01000044_gene1085	2.72e-135	384.0	COG0118@1|root,COG0118@2|Bacteria,1TQT0@1239|Firmicutes,248SH@186801|Clostridia,3XZAS@572511|Blautia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR	hisH	-	-	ko:K02501	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	-	GATase
NFNHFNFO_03611	33035.JPJF01000044_gene1086	1.63e-149	423.0	COG0106@1|root,COG0106@2|Bacteria,1V1IR@1239|Firmicutes,24GBJ@186801|Clostridia	186801|Clostridia	E	1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase	hisA	-	5.3.1.16	ko:K01814	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04640	RC00945	ko00000,ko00001,ko00002,ko01000	-	-	-	His_biosynth
NFNHFNFO_03612	33035.JPJF01000044_gene1087	1.88e-174	487.0	COG0107@1|root,COG0107@2|Bacteria,1TP0W@1239|Firmicutes,24900@186801|Clostridia,3XZ31@572511|Blautia	186801|Clostridia	E	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit	hisF	-	-	ko:K02500	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04558	RC00010,RC01190,RC01943	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05755	His_biosynth
NFNHFNFO_03613	33035.JPJF01000044_gene1088	4.03e-63	194.0	COG0139@1|root,COG0139@2|Bacteria,1UYNA@1239|Firmicutes,247RS@186801|Clostridia,3XZDT@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	hisI	-	3.5.4.19,3.6.1.31	ko:K01496,ko:K11755	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035,R04037	RC00002,RC01055	ko00000,ko00001,ko00002,ko01000	-	-	iHN637.CLJU_RS05760	His_biosynth,PRA-CH,PRA-PH
NFNHFNFO_03614	33035.JPJF01000044_gene1089	1.45e-67	205.0	COG0140@1|root,COG0140@2|Bacteria,1VB6S@1239|Firmicutes,24MP1@186801|Clostridia	186801|Clostridia	E	Phosphoribosyl-ATP	hisE	-	3.6.1.31	ko:K01523	ko00340,ko01100,ko01110,ko01230,map00340,map01100,map01110,map01230	M00026	R04035	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	PRA-PH
NFNHFNFO_03615	33035.JPJF01000044_gene1097	1.91e-128	367.0	29UT2@1|root,30G5C@2|Bacteria,1UF7K@1239|Firmicutes,25K8E@186801|Clostridia,3Y1QV@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03616	33035.JPJF01000044_gene1098	1.87e-127	363.0	COG4869@1|root,COG4869@2|Bacteria,1V242@1239|Firmicutes,24EHP@186801|Clostridia,3Y2C4@572511|Blautia	186801|Clostridia	Q	Phosphate propanoyltransferase	-	-	2.3.1.8	ko:K15024	ko00430,ko00620,ko00640,ko00720,ko01100,ko01120,ko01200,map00430,map00620,map00640,map00720,map01100,map01120,map01200	M00579	R00230,R00921	RC00004,RC02746,RC02816	ko00000,ko00001,ko00002,ko01000	-	-	-	PTAC
NFNHFNFO_03617	33035.JPJF01000044_gene1099	1.52e-181	511.0	COG5464@1|root,COG5464@2|Bacteria,1V2I2@1239|Firmicutes	1239|Firmicutes	S	transposase or invertase	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03618	33035.JPJF01000044_gene1100	1.49e-194	542.0	COG1105@1|root,COG1105@2|Bacteria,1TQ36@1239|Firmicutes,249RK@186801|Clostridia,3XZ0R@572511|Blautia	186801|Clostridia	H	Belongs to the carbohydrate kinase PfkB family. LacC subfamily	pfkB	-	2.7.1.56	ko:K00882	ko00051,map00051	-	R02071	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	PfkB
NFNHFNFO_03619	33035.JPJF01000044_gene1101	0.0	1157.0	COG1299@1|root,COG1445@1|root,COG1762@1|root,COG1299@2|Bacteria,COG1445@2|Bacteria,COG1762@2|Bacteria,1TPKU@1239|Firmicutes,248V6@186801|Clostridia,3XZB2@572511|Blautia	186801|Clostridia	GT	Psort location CytoplasmicMembrane, score 10.00	fruA	-	2.7.1.202	ko:K02768,ko:K02769,ko:K02770	ko00051,ko01100,ko01120,ko02060,map00051,map01100,map01120,map02060	M00273	R03232	RC00017,RC03206	ko00000,ko00001,ko00002,ko01000,ko02000	4.A.2.1	-	-	PTS_EIIA_2,PTS_EIIC,PTS_IIB
NFNHFNFO_03620	33035.JPJF01000044_gene1102	1.6e-49	157.0	COG1925@1|root,COG1925@2|Bacteria,1VE7N@1239|Firmicutes,24Q2D@186801|Clostridia,3Y0JB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score	ptsH	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NFNHFNFO_03621	33035.JPJF01000044_gene1103	0.0	982.0	COG1080@1|root,COG1080@2|Bacteria,1TPK8@1239|Firmicutes,248QP@186801|Clostridia,3XZ65@572511|Blautia	186801|Clostridia	G	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)	ptsP	-	2.7.3.9,2.7.9.2	ko:K01007,ko:K08483	ko00620,ko00680,ko00720,ko01100,ko01120,ko01200,ko02060,map00620,map00680,map00720,map01100,map01120,map01200,map02060	M00173,M00374	R00199	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko02000	8.A.7	-	-	PEP-utilisers_N,PEP-utilizers,PEP-utilizers_C
NFNHFNFO_03622	33035.JPJF01000044_gene1104	7.76e-156	439.0	COG1349@1|root,COG1349@2|Bacteria,1TSF8@1239|Firmicutes,2498W@186801|Clostridia,3XYWN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	fruR	-	-	ko:K03436	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
NFNHFNFO_03623	33035.JPJF01000044_gene1112	1.07e-93	274.0	COG1846@1|root,COG1846@2|Bacteria,1V6GY@1239|Firmicutes,24HTB@186801|Clostridia,3Y09U@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_27,MarR,MarR_2
NFNHFNFO_03624	33035.JPJF01000044_gene1113	0.0	1110.0	COG4805@1|root,COG4805@2|Bacteria,1TREN@1239|Firmicutes,249U9@186801|Clostridia,3XYKE@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	DUF885
NFNHFNFO_03625	33035.JPJF01000044_gene1114	7.35e-260	719.0	2DM0D@1|root,314WJ@2|Bacteria,1V87M@1239|Firmicutes,24JNN@186801|Clostridia,3Y15V@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03626	33035.JPJF01000044_gene1115	7.81e-208	576.0	COG0492@1|root,COG0492@2|Bacteria,1TNZS@1239|Firmicutes,2491M@186801|Clostridia,3XZ6G@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	trxB	-	1.8.1.9	ko:K00384	ko00450,map00450	-	R02016,R03596,R09372	RC00013,RC02518,RC02873	ko00000,ko00001,ko01000	-	-	-	Pyr_redox_2
NFNHFNFO_03627	33035.JPJF01000044_gene1116	9.67e-289	790.0	COG0153@1|root,COG0153@2|Bacteria,1TPD0@1239|Firmicutes,247U8@186801|Clostridia,3XZFW@572511|Blautia	186801|Clostridia	G	Galactokinase galactose-binding signature	galK	-	2.7.1.6	ko:K00849	ko00052,ko00520,ko01100,map00052,map00520,map01100	M00554,M00632	R01092	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	GHMP_kinases_C,GHMP_kinases_N,GalKase_gal_bdg
NFNHFNFO_03628	33035.JPJF01000044_gene1117	3.32e-52	167.0	COG1695@1|root,COG1695@2|Bacteria,1VAGB@1239|Firmicutes,24MZ2@186801|Clostridia,3Y20G@572511|Blautia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	ko:K10947	-	-	-	-	ko00000,ko03000	-	-	-	PadR
NFNHFNFO_03629	33035.JPJF01000044_gene1118	1.44e-85	258.0	COG4817@1|root,COG4817@2|Bacteria,1V8KV@1239|Firmicutes,25D3C@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1048)	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03630	33035.JPJF01000057_gene3070	0.0	952.0	COG5002@1|root,COG5002@2|Bacteria,1TQ1H@1239|Firmicutes,247VG@186801|Clostridia,3XZMN@572511|Blautia	186801|Clostridia	T	Single Cache-like	phoR	-	2.7.13.3	ko:K07636	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA,PAS,PAS_4,PAS_9,sCache_like
NFNHFNFO_03631	33035.JPJF01000057_gene3071	1.67e-151	427.0	COG0745@1|root,COG0745@2|Bacteria,1TQY9@1239|Firmicutes,24EFS@186801|Clostridia,3XYU2@572511|Blautia	186801|Clostridia	KT	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K07658	ko02020,map02020	M00434	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_03632	33035.JPJF01000057_gene3072	2.01e-141	401.0	COG0704@1|root,COG0704@2|Bacteria,1URN3@1239|Firmicutes,24FTM@186801|Clostridia,3XZTS@572511|Blautia	186801|Clostridia	P	Plays a role in the regulation of phosphate uptake	phoU	GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186	-	ko:K02039	-	-	-	-	ko00000	-	-	-	PhoU
NFNHFNFO_03633	33035.JPJF01000057_gene3073	5.63e-176	491.0	COG1117@1|root,COG1117@2|Bacteria,1TP1M@1239|Firmicutes,247RD@186801|Clostridia,3XYGV@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system	pstB	-	3.6.3.27	ko:K02036	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.7	-	-	ABC_tran
NFNHFNFO_03634	33035.JPJF01000057_gene3074	7.42e-178	498.0	COG0581@1|root,COG0581@2|Bacteria,1TP74@1239|Firmicutes,248C4@186801|Clostridia,3XYWM@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	pstA	-	-	ko:K02038	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
NFNHFNFO_03635	33035.JPJF01000057_gene3075	4.26e-181	506.0	COG0573@1|root,COG0573@2|Bacteria,1TSPP@1239|Firmicutes,249KQ@186801|Clostridia,3XZ6A@572511|Blautia	186801|Clostridia	P	probably responsible for the translocation of the substrate across the membrane	pstC	-	-	ko:K02037	ko02010,map02010	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	BPD_transp_1
NFNHFNFO_03636	33035.JPJF01000057_gene3076	4.73e-174	491.0	COG0226@1|root,COG0226@2|Bacteria,1TQ5X@1239|Firmicutes,248QU@186801|Clostridia,3XYMF@572511|Blautia	186801|Clostridia	P	COG COG0226 ABC-type phosphate transport system, periplasmic component	pstS	-	-	ko:K02040	ko02010,ko02020,ko05152,map02010,map02020,map05152	M00222	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.7	-	-	PBP_like_2
NFNHFNFO_03637	33035.JPJF01000057_gene3078	1.09e-132	377.0	COG1394@1|root,COG1394@2|Bacteria,1TQ4P@1239|Firmicutes,24Z7J@186801|Clostridia,3XYVE@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
NFNHFNFO_03638	33035.JPJF01000057_gene3079	0.0	905.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,3XZA3@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	ntpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
NFNHFNFO_03639	33035.JPJF01000057_gene3080	0.0	1151.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,3XYVX@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
NFNHFNFO_03640	33035.JPJF01000057_gene3081	1.44e-118	341.0	COG1390@1|root,COG1390@2|Bacteria,1V7UJ@1239|Firmicutes,24ICM@186801|Clostridia,3Y0B1@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	vATP-synt_E
NFNHFNFO_03641	33035.JPJF01000057_gene3082	4.03e-64	196.0	COG1436@1|root,COG1436@2|Bacteria,1VEN1@1239|Firmicutes,24K2E@186801|Clostridia,3Y07R@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
NFNHFNFO_03642	33035.JPJF01000057_gene3083	8.08e-78	234.0	COG0636@1|root,COG0636@2|Bacteria,1VAGE@1239|Firmicutes,24RB6@186801|Clostridia,3Y0BA@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
NFNHFNFO_03643	33035.JPJF01000057_gene3084	0.0	1235.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,3XZ9K@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
NFNHFNFO_03644	33035.JPJF01000057_gene3085	1.94e-246	677.0	COG1527@1|root,COG1527@2|Bacteria,1U1QE@1239|Firmicutes,24A4E@186801|Clostridia,3XZ0T@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
NFNHFNFO_03645	33035.JPJF01000057_gene3086	1.53e-44	146.0	2EC7P@1|root,33668@2|Bacteria,1VHK0@1239|Firmicutes,24R0C@186801|Clostridia,3Y0UW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03646	33035.JPJF01000057_gene3087	2.49e-148	418.0	COG0220@1|root,COG0220@2|Bacteria,1TQCA@1239|Firmicutes,248YR@186801|Clostridia,3XZ71@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA	trmB	-	2.1.1.33	ko:K03439	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	Methyltransf_4
NFNHFNFO_03648	33035.JPJF01000057_gene3089	1.03e-70	213.0	COG3118@1|root,COG3118@2|Bacteria,1VA3Y@1239|Firmicutes,24MM5@186801|Clostridia	186801|Clostridia	O	Belongs to the thioredoxin family	trxA	-	-	ko:K03671	ko04621,ko05418,map04621,map05418	-	-	-	ko00000,ko00001,ko03110	-	-	-	Thioredoxin
NFNHFNFO_03650	693746.OBV_29870	1.22e-84	255.0	COG1396@1|root,COG2033@1|root,COG1396@2|Bacteria,COG2033@2|Bacteria,1W1Q8@1239|Firmicutes,25EKH@186801|Clostridia,2N7IV@216572|Oscillospiraceae	186801|Clostridia	K	Desulfoferrodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,Desulfoferrodox,HTH_3
NFNHFNFO_03651	33035.JPJF01000057_gene3090	2.7e-166	468.0	COG0778@1|root,COG0778@2|Bacteria,1UY72@1239|Firmicutes,248YJ@186801|Clostridia	186801|Clostridia	C	nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Nitroreductase
NFNHFNFO_03653	33035.JPJF01000057_gene3094	1.24e-237	654.0	COG0451@1|root,COG0451@2|Bacteria,1TPYA@1239|Firmicutes,24A39@186801|Clostridia	186801|Clostridia	GM	Epimerase dehydratase	-	-	-	-	-	-	-	-	-	-	-	-	Epimerase
NFNHFNFO_03654	33035.JPJF01000057_gene3095	2.52e-87	258.0	COG1610@1|root,COG1610@2|Bacteria,1V6F2@1239|Firmicutes,24JB0@186801|Clostridia,3Y076@572511|Blautia	186801|Clostridia	S	Yqey-like protein	yqeY	-	-	ko:K09117	-	-	-	-	ko00000	-	-	-	YqeY
NFNHFNFO_03655	33035.JPJF01000057_gene3096	1.01e-140	398.0	COG2860@1|root,COG2860@2|Bacteria,1UH1K@1239|Firmicutes,24HHG@186801|Clostridia,3XYJI@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	yicG	-	-	-	-	-	-	-	-	-	-	-	UPF0126
NFNHFNFO_03656	33035.JPJF01000057_gene3097	1.92e-300	821.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3Y12F@572511|Blautia	186801|Clostridia	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NFNHFNFO_03657	33035.JPJF01000057_gene3098	0.0	1003.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TSK4@1239|Firmicutes,24DXH@186801|Clostridia,3Y1DR@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
NFNHFNFO_03658	33035.JPJF01000057_gene3099	0.0	1069.0	COG2972@1|root,COG2972@2|Bacteria,1TSE1@1239|Firmicutes,24B0H@186801|Clostridia,3Y124@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NFNHFNFO_03659	33035.JPJF01000057_gene3100	1.87e-298	815.0	COG2182@1|root,COG2182@2|Bacteria,1UI14@1239|Firmicutes,25EA2@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_03660	33035.JPJF01000057_gene3101	9e-189	526.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AMT@186801|Clostridia,3Y15X@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_03661	33035.JPJF01000057_gene3102	7.06e-191	531.0	COG0395@1|root,COG0395@2|Bacteria,1TSJ9@1239|Firmicutes,24ERB@186801|Clostridia,3Y1FC@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_03662	33035.JPJF01000057_gene3103	3.12e-275	751.0	COG4030@1|root,COG4030@2|Bacteria,1TRZY@1239|Firmicutes,249GP@186801|Clostridia,3XYWH@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF2961)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2961
NFNHFNFO_03663	33035.JPJF01000057_gene3104	1.37e-244	677.0	COG1653@1|root,COG1653@2|Bacteria,1TQJU@1239|Firmicutes,24AHT@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_03664	33035.JPJF01000057_gene3105	8.94e-272	744.0	COG0281@1|root,COG0281@2|Bacteria,1TPJ3@1239|Firmicutes,2487U@186801|Clostridia,3XYME@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.1.1.38	ko:K00027	ko00620,ko01200,ko02020,map00620,map01200,map02020	-	R00214	RC00105	ko00000,ko00001,ko01000	-	-	-	Malic_M,malic
NFNHFNFO_03665	33035.JPJF01000057_gene3106	1.03e-223	620.0	COG3594@1|root,COG3594@2|Bacteria,1TPGY@1239|Firmicutes,24IKC@186801|Clostridia,3Y0PP@572511|Blautia	186801|Clostridia	G	Acyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Acyl_transf_3
NFNHFNFO_03666	33035.JPJF01000057_gene3107	1.34e-245	686.0	COG2843@1|root,COG2843@2|Bacteria,1UZW4@1239|Firmicutes,24950@186801|Clostridia,3Y12V@572511|Blautia	186801|Clostridia	M	Bacterial capsule synthesis protein PGA_cap	capA	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
NFNHFNFO_03668	33035.JPJF01000057_gene3109	5.67e-205	569.0	COG0031@1|root,COG0031@2|Bacteria,1TP30@1239|Firmicutes,2497G@186801|Clostridia,3XZJH@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	cysK	-	2.5.1.47	ko:K01738	ko00270,ko00920,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00270,map00920,map01100,map01110,map01120,map01130,map01200,map01230	M00021	R00897,R03601,R04859	RC00020,RC02814,RC02821	ko00000,ko00001,ko00002,ko01000	-	-	-	PALP
NFNHFNFO_03669	33035.JPJF01000057_gene3110	3.61e-277	763.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,3XYK2@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_03670	33035.JPJF01000057_gene3111	9.94e-104	301.0	COG2606@1|root,COG2606@2|Bacteria,1V6JF@1239|Firmicutes,24I4E@186801|Clostridia,3XZYY@572511|Blautia	186801|Clostridia	S	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily	ybaK	-	-	ko:K03976	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	tRNA_edit
NFNHFNFO_03671	33035.JPJF01000057_gene3112	2.24e-140	397.0	COG2755@1|root,COG2755@2|Bacteria,1V2BU@1239|Firmicutes,24BSW@186801|Clostridia,3Y0F9@572511|Blautia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NFNHFNFO_03672	33035.JPJF01000057_gene3113	5.05e-104	302.0	COG4960@1|root,COG4960@2|Bacteria,1UPND@1239|Firmicutes,25HJR@186801|Clostridia,3Y0GG@572511|Blautia	186801|Clostridia	OU	Type IV leader peptidase family	-	-	3.4.23.43	ko:K02278	-	-	-	-	ko00000,ko01000,ko02035,ko02044	-	-	-	Peptidase_A24
NFNHFNFO_03673	33035.JPJF01000057_gene3114	4.35e-194	543.0	COG1192@1|root,COG1192@2|Bacteria,1V11K@1239|Firmicutes,24FDX@186801|Clostridia,3XZ68@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	AAA_31
NFNHFNFO_03674	537007.BLAHAN_04120	4.51e-173	495.0	COG4962@1|root,COG4962@2|Bacteria,1TQ0Z@1239|Firmicutes,249VS@186801|Clostridia,3XZAC@572511|Blautia	186801|Clostridia	U	flp pilus assembly ATPase CpaF	ptlH	-	-	ko:K02283	-	-	-	-	ko00000,ko02035,ko02044	-	-	-	T2SSE
NFNHFNFO_03675	33035.JPJF01000043_gene989	4.94e-162	455.0	COG4965@1|root,COG4965@2|Bacteria,1V6PB@1239|Firmicutes,24JBR@186801|Clostridia,3XZRG@572511|Blautia	186801|Clostridia	U	Psort location CytoplasmicMembrane, score	tadB	-	-	ko:K12510	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
NFNHFNFO_03676	33035.JPJF01000043_gene988	3.01e-209	588.0	COG2064@1|root,COG2064@2|Bacteria,1V2C3@1239|Firmicutes,24AN4@186801|Clostridia,3Y01Z@572511|Blautia	186801|Clostridia	NU	Psort location CytoplasmicMembrane, score	-	-	-	ko:K12511	-	-	-	-	ko00000,ko02044	-	-	-	T2SSF
NFNHFNFO_03677	33035.JPJF01000043_gene987	3.06e-24	92.0	2EHSI@1|root,33BI9@2|Bacteria,1VK7K@1239|Firmicutes,24UF9@186801|Clostridia,3Y0UH@572511|Blautia	186801|Clostridia	S	Putative Flagellin, Flp1-like, domain	-	-	-	-	-	-	-	-	-	-	-	-	Flp1_like
NFNHFNFO_03678	33035.JPJF01000043_gene986	4.37e-279	769.0	2BXNJ@1|root,2ZC8M@2|Bacteria,1UYM5@1239|Firmicutes,24B1U@186801|Clostridia,3Y2CX@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03679	33035.JPJF01000043_gene985	3.68e-175	491.0	COG4961@1|root,COG4961@2|Bacteria,1V9E1@1239|Firmicutes,24ET0@186801|Clostridia,3Y0C5@572511|Blautia	186801|Clostridia	U	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TadE
NFNHFNFO_03680	556261.HMPREF0240_03284	1.29e-10	63.2	COG1989@1|root,COG1989@2|Bacteria,1VMFT@1239|Firmicutes,24T4E@186801|Clostridia,36T28@31979|Clostridiaceae	186801|Clostridia	NOU	Type IV leader peptidase family	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_A24
NFNHFNFO_03681	33035.JPJF01000043_gene983	9.28e-75	226.0	2EQ3G@1|root,33HPU@2|Bacteria,1VKDW@1239|Firmicutes,24V35@186801|Clostridia,3Y0MK@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	TadE
NFNHFNFO_03682	33035.JPJF01000043_gene982	2.37e-212	600.0	COG1716@1|root,COG1716@2|Bacteria,1V550@1239|Firmicutes,24BVK@186801|Clostridia,3Y02T@572511|Blautia	186801|Clostridia	T	Inner membrane component of T3SS, cytoplasmic domain	-	-	-	-	-	-	-	-	-	-	-	-	FHA
NFNHFNFO_03683	33035.JPJF01000043_gene981	1.28e-145	411.0	COG0705@1|root,COG0705@2|Bacteria,1TQXT@1239|Firmicutes,247PT@186801|Clostridia,3XZZ9@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	gluP	-	3.4.21.105	ko:K19225	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Rhomboid
NFNHFNFO_03684	33035.JPJF01000043_gene980	6.31e-126	361.0	COG5000@1|root,COG5000@2|Bacteria,1VANU@1239|Firmicutes,24ETV@186801|Clostridia	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
NFNHFNFO_03685	33035.JPJF01000043_gene979	3.03e-95	278.0	COG0537@1|root,COG0537@2|Bacteria,1V9ZJ@1239|Firmicutes,24JCW@186801|Clostridia,3Y034@572511|Blautia	186801|Clostridia	FG	Psort location Cytoplasmic, score 8.87	hit	-	-	ko:K02503	-	-	-	-	ko00000,ko04147	-	-	-	HIT
NFNHFNFO_03686	33035.JPJF01000043_gene978	1.08e-102	299.0	COG1595@1|root,COG1595@2|Bacteria,1VGSN@1239|Firmicutes,251Y8@186801|Clostridia,3Y0JK@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	DUF134,Sigma70_r2
NFNHFNFO_03687	33035.JPJF01000043_gene977	2.58e-239	660.0	COG0707@1|root,COG0707@2|Bacteria,1TQFT@1239|Firmicutes,248IA@186801|Clostridia,3XYKG@572511|Blautia	186801|Clostridia	M	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)	murG	-	2.4.1.227	ko:K02563	ko00550,ko01100,ko01502,ko04112,map00550,map01100,map01502,map04112	-	R05032,R05662	RC00005,RC00049	ko00000,ko00001,ko01000,ko01011	-	GT28	-	Glyco_tran_28_C,Glyco_transf_28
NFNHFNFO_03688	33035.JPJF01000043_gene976	2.91e-114	340.0	2D2TB@1|root,32TDJ@2|Bacteria,1VB0C@1239|Firmicutes,24RN7@186801|Clostridia,3Y0P2@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF4367
NFNHFNFO_03689	537007.BLAHAN_04105	5.52e-46	154.0	2DSCU@1|root,33FK5@2|Bacteria,1VKPN@1239|Firmicutes,24K3M@186801|Clostridia,3Y0VV@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03690	33035.JPJF01000043_gene975	0.0	1067.0	COG1236@1|root,COG1236@2|Bacteria,1TQBH@1239|Firmicutes,248QR@186801|Clostridia,3XZEM@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07576	-	-	-	-	ko00000	-	-	-	Beta-Casp,Lactamase_B,Lactamase_B_6,RMMBL
NFNHFNFO_03691	33035.JPJF01000043_gene974	0.0	957.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,3XYYT@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	-	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
NFNHFNFO_03692	33035.JPJF01000043_gene973	1.6e-58	181.0	2DPI5@1|root,3326E@2|Bacteria,1VIQZ@1239|Firmicutes,24QSZ@186801|Clostridia,3Y27B@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03693	33035.JPJF01000043_gene972	1.69e-75	226.0	2DRY9@1|root,33DNC@2|Bacteria,1V1G6@1239|Firmicutes,24GGT@186801|Clostridia,3Y05P@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03694	33035.JPJF01000043_gene971	9.5e-68	205.0	COG1695@1|root,COG1695@2|Bacteria,1VA8U@1239|Firmicutes,25N2M@186801|Clostridia,3Y1W0@572511|Blautia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
NFNHFNFO_03695	33035.JPJF01000043_gene970	1.91e-104	306.0	COG4709@1|root,COG4709@2|Bacteria,1V5ZC@1239|Firmicutes,25CU8@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF1700)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1700
NFNHFNFO_03697	33035.JPJF01000043_gene968	3e-131	374.0	COG2197@1|root,COG2197@2|Bacteria,1TQ1U@1239|Firmicutes,25B1X@186801|Clostridia,3XZYD@572511|Blautia	186801|Clostridia	T	COG COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GerE,Response_reg
NFNHFNFO_03698	33035.JPJF01000043_gene967	2.54e-199	558.0	COG4585@1|root,COG4585@2|Bacteria,1UUZ9@1239|Firmicutes,248T2@186801|Clostridia,3Y033@572511|Blautia	186801|Clostridia	T	COG COG4585 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA_3
NFNHFNFO_03699	33035.JPJF01000043_gene966	1.19e-206	573.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia,3XYW7@572511|Blautia	186801|Clostridia	V	COG COG1131 ABC-type multidrug transport system, ATPase component	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran,DUF4162
NFNHFNFO_03700	33035.JPJF01000043_gene965	1.71e-213	596.0	COG0842@1|root,COG0842@2|Bacteria,1TR76@1239|Firmicutes,24A0F@186801|Clostridia,3Y0BD@572511|Blautia	186801|Clostridia	V	COG COG0842 ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
NFNHFNFO_03701	33035.JPJF01000043_gene964	4.51e-251	693.0	COG0842@1|root,COG0842@2|Bacteria,1UYEY@1239|Firmicutes,24BCP@186801|Clostridia,3Y0H1@572511|Blautia	186801|Clostridia	V	COG COG0842 ABC-type multidrug transport system, permease component	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_3
NFNHFNFO_03702	33035.JPJF01000043_gene963	1.43e-210	587.0	COG1055@1|root,COG1055@2|Bacteria,1TQCH@1239|Firmicutes,25CD7@186801|Clostridia,3XZ25@572511|Blautia	186801|Clostridia	P	Citrate transporter	ybiR	-	-	-	-	-	-	-	-	-	-	-	CitMHS
NFNHFNFO_03703	33035.JPJF01000043_gene962	1.74e-53	167.0	2E3FD@1|root,32YE7@2|Bacteria,1VEE4@1239|Firmicutes,24QJ7@186801|Clostridia,3Y0NQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TSCPD
NFNHFNFO_03704	1196322.A370_02998	3.27e-105	320.0	COG2199@1|root,COG4251@1|root,COG3706@2|Bacteria,COG4251@2|Bacteria,1V3JC@1239|Firmicutes,25FH3@186801|Clostridia	186801|Clostridia	T	serine threonine protein kinase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,HATPase_c,Response_reg
NFNHFNFO_03705	203119.Cthe_1825	1.25e-127	414.0	COG0642@1|root,COG2972@1|root,COG0642@2|Bacteria,COG2972@2|Bacteria,1UYZX@1239|Firmicutes,25E9T@186801|Clostridia,3WSIY@541000|Ruminococcaceae	186801|Clostridia	T	Histidine Phosphotransfer domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,Response_reg,dCache_1
NFNHFNFO_03706	1196322.A370_03000	1.22e-76	246.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TT49@1239|Firmicutes,24DUZ@186801|Clostridia,36FC2@31979|Clostridiaceae	186801|Clostridia	T	response regulator	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,Response_reg
NFNHFNFO_03707	1196322.A370_03001	2.41e-161	468.0	COG0683@1|root,COG0683@2|Bacteria,1V3KZ@1239|Firmicutes	1239|Firmicutes	E	Urea ABC transporter, urea binding protein	-	-	-	ko:K01999,ko:K11959	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	Peripla_BP_5,Peripla_BP_6
NFNHFNFO_03708	658086.HMPREF0994_04610	4.74e-135	391.0	COG0559@1|root,COG0559@2|Bacteria,1TR24@1239|Firmicutes,2480A@186801|Clostridia,27K8D@186928|unclassified Lachnospiraceae	186801|Clostridia	E	Branched-chain amino acid transport system / permease component	-	-	-	ko:K01997,ko:K11960	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
NFNHFNFO_03709	658086.HMPREF0994_04609	9.27e-158	455.0	COG4177@1|root,COG4177@2|Bacteria,1TPMZ@1239|Firmicutes,248WH@186801|Clostridia	186801|Clostridia	E	Belongs to the binding-protein-dependent transport system permease family	-	-	-	ko:K01998,ko:K11961	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	BPD_transp_2
NFNHFNFO_03710	1196322.A370_03004	1.26e-106	315.0	COG4674@1|root,COG4674@2|Bacteria,1UIU8@1239|Firmicutes,25ES1@186801|Clostridia	186801|Clostridia	S	TIGRFAM urea ABC transporter, ATP-binding protein UrtD	-	-	-	ko:K11962	ko02010,map02010	M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran,BCA_ABC_TP_C
NFNHFNFO_03711	658086.HMPREF0994_04607	2.52e-103	305.0	COG0410@1|root,COG0410@2|Bacteria,1TPW4@1239|Firmicutes,247PN@186801|Clostridia,27IPQ@186928|unclassified Lachnospiraceae	186801|Clostridia	E	ABC transporter	-	-	-	ko:K01996,ko:K11963	ko02010,ko02024,map02010,map02024	M00237,M00323	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.4,3.A.1.4.4,3.A.1.4.5	-	-	ABC_tran
NFNHFNFO_03712	632245.CLP_1058	1.82e-38	131.0	COG0347@1|root,COG0347@2|Bacteria,1VASB@1239|Firmicutes,24J84@186801|Clostridia,36JNI@31979|Clostridiaceae	186801|Clostridia	K	Belongs to the P(II) protein family	-	-	-	ko:K02589	-	-	-	-	ko00000	-	-	-	P-II
NFNHFNFO_03713	931276.Cspa_c30930	1.51e-24	97.1	COG0347@1|root,COG0347@2|Bacteria,1VB4G@1239|Firmicutes,24MQ1@186801|Clostridia,36JU9@31979|Clostridiaceae	186801|Clostridia	K	PFAM Nitrogen regulatory protein P-II	-	-	-	ko:K02590	-	-	-	-	ko00000	-	-	-	P-II
NFNHFNFO_03714	1042156.CXIVA_01340	1.91e-242	667.0	COG0388@1|root,COG0388@2|Bacteria,1UYBG@1239|Firmicutes	1239|Firmicutes	S	Is an aliphatic amidase with a restricted substrate specificity, as it only hydrolyzes formamide	amiF	-	3.5.1.49	ko:K01455	ko00460,ko00630,ko00910,ko01200,map00460,map00630,map00910,map01200	-	R00524	RC02432,RC02810	ko00000,ko00001,ko01000	-	-	-	CN_hydrolase
NFNHFNFO_03715	1042156.CXIVA_25630	4.88e-51	162.0	COG0831@1|root,COG0831@2|Bacteria,1V7GU@1239|Firmicutes,24MN2@186801|Clostridia,36M20@31979|Clostridiaceae	186801|Clostridia	E	Belongs to the urease gamma subunit family	ureA	-	3.5.1.5	ko:K01430	ko00220,ko00230,ko00791,ko01100,ko01120,map00220,map00230,map00791,map01100,map01120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_gamma
NFNHFNFO_03716	1235802.C823_05376	1.2e-52	168.0	COG0832@1|root,COG0832@2|Bacteria,1VAIA@1239|Firmicutes,24N65@186801|Clostridia	186801|Clostridia	E	Belongs to the urease beta subunit family	ureB	-	3.5.1.5	ko:K01429,ko:K14048	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Urease_beta,Urease_gamma
NFNHFNFO_03717	457412.RSAG_01445	0.0	1014.0	COG0804@1|root,COG0804@2|Bacteria,1TPQP@1239|Firmicutes,24D62@186801|Clostridia,3WGSE@541000|Ruminococcaceae	186801|Clostridia	E	Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family	ureC	-	3.5.1.5	ko:K01428	ko00220,ko00230,ko00791,ko01100,ko01120,ko05120,map00220,map00230,map00791,map01100,map01120,map05120	-	R00131	RC02798,RC02806	ko00000,ko00001,ko01000	-	-	-	Amidohydro_1,Urease_alpha
NFNHFNFO_03718	1121115.AXVN01000010_gene2765	7.95e-57	182.0	COG2371@1|root,COG2371@2|Bacteria,1V7SB@1239|Firmicutes,25DT7@186801|Clostridia	186801|Clostridia	O	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly	ureE	-	-	ko:K03187	-	-	-	-	ko00000	-	-	-	UreE_C,UreE_N
NFNHFNFO_03719	1292035.H476_2651	1.87e-80	247.0	COG0830@1|root,COG0830@2|Bacteria,1V2H0@1239|Firmicutes,24ETM@186801|Clostridia	186801|Clostridia	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureF	-	-	ko:K03188	-	-	-	-	ko00000	-	-	-	UreF
NFNHFNFO_03720	1121115.AXVN01000010_gene2767	2.19e-123	353.0	COG0378@1|root,COG0378@2|Bacteria,1TS00@1239|Firmicutes,248T1@186801|Clostridia,3XZ4U@572511|Blautia	186801|Clostridia	KO	UreA amidohydrolase (urease) regulatory and maturation protein UreG	hypB	-	-	ko:K04652	-	-	-	-	ko00000,ko03110	-	-	-	cobW
NFNHFNFO_03721	397291.C804_01951	7.28e-76	238.0	COG0829@1|root,COG0829@2|Bacteria,1TVM2@1239|Firmicutes,24D1J@186801|Clostridia,27QK7@186928|unclassified Lachnospiraceae	186801|Clostridia	O	Required for maturation of urease via the functional incorporation of the urease nickel metallocenter	ureD	-	-	ko:K03190	-	-	-	-	ko00000	-	-	-	UreD
NFNHFNFO_03722	33035.JPJF01000043_gene959	4.46e-122	356.0	COG4968@1|root,COG4968@2|Bacteria,1VHI4@1239|Firmicutes,24R5K@186801|Clostridia	186801|Clostridia	NU	Prokaryotic N-terminal methylation motif	-	-	-	-	-	-	-	-	-	-	-	-	N_methyl
NFNHFNFO_03723	33035.JPJF01000043_gene958	1.42e-289	792.0	COG3629@1|root,COG3629@2|Bacteria,1UWHI@1239|Firmicutes,24AC8@186801|Clostridia,3Y188@572511|Blautia	186801|Clostridia	T	Bacterial transcriptional activator domain	-	-	-	-	-	-	-	-	-	-	-	-	BTAD,GGDEF,Trans_reg_C
NFNHFNFO_03724	33035.JPJF01000043_gene957	5.7e-89	262.0	2E82R@1|root,332GR@2|Bacteria,1VEUI@1239|Firmicutes,24QMN@186801|Clostridia,3Y1WP@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03725	33035.JPJF01000043_gene956	1.06e-38	129.0	2E82R@1|root,33CWV@2|Bacteria,1VME1@1239|Firmicutes,24UIA@186801|Clostridia,3Y234@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03726	1504823.CCMM01000005_gene155	3.47e-280	842.0	COG2304@1|root,COG4932@1|root,COG2304@2|Bacteria,COG4932@2|Bacteria	2|Bacteria	M	domain protein	-	-	-	ko:K07114	-	-	-	-	ko00000,ko02000	1.A.13.2.2,1.A.13.2.3	-	-	FG-GAP,VCBS,VWA,VWA_3
NFNHFNFO_03727	411468.CLOSCI_01049	1.29e-34	143.0	COG4932@1|root,COG4932@2|Bacteria,1UVH8@1239|Firmicutes,24WIY@186801|Clostridia	186801|Clostridia	M	LPXTG cell wall anchor motif	-	-	-	-	-	-	-	-	-	-	-	-	Gram_pos_anchor
NFNHFNFO_03728	33035.JPJF01000043_gene953	1.85e-175	493.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,3Y0YU@572511|Blautia	186801|Clostridia	M	Sortase family	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NFNHFNFO_03729	33035.JPJF01000043_gene952	4.31e-199	552.0	COG3764@1|root,COG3764@2|Bacteria,1UN9R@1239|Firmicutes,24CEQ@186801|Clostridia,3XZWU@572511|Blautia	186801|Clostridia	M	COG COG3764 Sortase (surface protein transpeptidase)	-	-	3.4.22.70	ko:K07284	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NFNHFNFO_03730	33035.JPJF01000043_gene951	3.26e-208	578.0	2BUGH@1|root,32PSI@2|Bacteria,1V6WG@1239|Firmicutes,24JP0@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03731	33035.JPJF01000043_gene950	2.17e-108	313.0	2E1E2@1|root,32WT6@2|Bacteria,1VE8G@1239|Firmicutes,24NJV@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03732	33035.JPJF01000043_gene949	1.15e-159	449.0	28NZ2@1|root,2ZBW1@2|Bacteria,1V2E1@1239|Firmicutes,24GPA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03733	33035.JPJF01000043_gene948	2.61e-157	444.0	29M7E@1|root,3084V@2|Bacteria,1V5XP@1239|Firmicutes,24J0I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03734	33035.JPJF01000043_gene947	3.02e-180	509.0	29RI3@1|root,30CM2@2|Bacteria,1V5K6@1239|Firmicutes,24IPS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03735	33035.JPJF01000043_gene946	1.29e-86	257.0	COG0681@1|root,COG0681@2|Bacteria,1V91S@1239|Firmicutes,25CNX@186801|Clostridia	186801|Clostridia	U	Peptidase S24-like	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_S24
NFNHFNFO_03736	622312.ROSEINA2194_00726	3.64e-11	59.3	2E82R@1|root,33CWV@2|Bacteria,1VME1@1239|Firmicutes,24UIA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03738	33035.JPJF01000043_gene943	0.0	1122.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia	186801|Clostridia	EG	Belongs to the IlvD Edd family	-	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
NFNHFNFO_03740	1123075.AUDP01000019_gene1617	1.24e-113	350.0	COG1541@1|root,COG1541@2|Bacteria,1TQA1@1239|Firmicutes,248G9@186801|Clostridia,3WS0T@541000|Ruminococcaceae	186801|Clostridia	H	AMP-binding enzyme	paaK	-	6.2.1.30	ko:K01912	ko00360,ko01120,ko05111,map00360,map01120,map05111	-	R02539	RC00004,RC00014	ko00000,ko00001,ko01000	-	-	-	AMP-binding,AMP-binding_C_2,LuxC
NFNHFNFO_03741	1123075.AUDP01000019_gene1616	5.3e-199	571.0	COG1964@1|root,COG1964@2|Bacteria,1TVES@1239|Firmicutes,248NC@186801|Clostridia,3WJ5T@541000|Ruminococcaceae	186801|Clostridia	S	Radical SAM superfamily	-	-	-	ko:K06937	-	-	-	-	ko00000,ko01000	-	-	-	Fer4_12,Fer4_14,Radical_SAM
NFNHFNFO_03742	1123075.AUDP01000019_gene1614	1.3e-144	421.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,3WH06@541000|Ruminococcaceae	186801|Clostridia	E	cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
NFNHFNFO_03743	1123075.AUDP01000019_gene1613	6.47e-61	202.0	COG2068@1|root,COG2068@2|Bacteria,1UY6E@1239|Firmicutes,249PV@186801|Clostridia	186801|Clostridia	G	HD domain	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
NFNHFNFO_03744	1123075.AUDP01000019_gene1612	4.6e-56	179.0	2E4P6@1|root,32ZHX@2|Bacteria,1VCAE@1239|Firmicutes,24PE5@186801|Clostridia,3WQJP@541000|Ruminococcaceae	186801|Clostridia	S	Putative redox-active protein (C_GCAxxG_C_C)	-	-	-	-	-	-	-	-	-	-	-	-	C_GCAxxG_C_C
NFNHFNFO_03745	65093.PCC7418_1000	7.8e-07	57.0	COG0500@1|root,COG2226@2|Bacteria,1G2F7@1117|Cyanobacteria	1117|Cyanobacteria	Q	Methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11,Methyltransf_25
NFNHFNFO_03746	1123075.AUDP01000019_gene1611	7.78e-38	127.0	2EGAW@1|root,33A2R@2|Bacteria,1VMAM@1239|Firmicutes,24WIE@186801|Clostridia,3WR2I@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03747	1123075.AUDP01000019_gene1610	1.95e-280	796.0	COG0247@1|root,COG0493@1|root,COG0247@2|Bacteria,COG0493@2|Bacteria,1TQ1A@1239|Firmicutes,248EK@186801|Clostridia,3WNTW@541000|Ruminococcaceae	186801|Clostridia	CE	Cysteine-rich domain	-	-	-	-	-	-	-	-	-	-	-	-	CCG,Fer4_17,Fer4_20,NAD_binding_8,Pyr_redox_2
NFNHFNFO_03748	1123075.AUDP01000019_gene1609	0.0	1684.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3WHIV@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	mop	-	1.2.99.7	ko:K07469	-	-	-	-	ko00000,ko01000	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
NFNHFNFO_03749	1123075.AUDP01000019_gene1608	1.37e-41	142.0	2E80U@1|root,332F1@2|Bacteria,1VGU4@1239|Firmicutes,25A2Q@186801|Clostridia,3WR2Z@541000|Ruminococcaceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03750	33035.JPJF01000043_gene942	1.56e-184	516.0	COG0329@1|root,COG0329@2|Bacteria,1V10S@1239|Firmicutes,2482C@186801|Clostridia,3Y1V0@572511|Blautia	186801|Clostridia	EM	Dihydrodipicolinate synthetase family	-	-	4.1.2.28	ko:K22397	ko00040,map00040	-	R01782	RC00307,RC00572	ko00000,ko00001,ko01000	-	-	-	DHDPS
NFNHFNFO_03751	33035.JPJF01000043_gene941	2.78e-157	442.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia,3XZ1X@572511|Blautia	186801|Clostridia	F	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	mtnN	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
NFNHFNFO_03752	33035.JPJF01000043_gene940	3.39e-150	427.0	2BAZ7@1|root,324F4@2|Bacteria,1UQQQ@1239|Firmicutes,258H1@186801|Clostridia,3Y1M7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03753	33035.JPJF01000043_gene939	0.0	866.0	COG0166@1|root,COG0166@2|Bacteria,1TP29@1239|Firmicutes,2487A@186801|Clostridia,3XYYG@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	pgi	-	5.3.1.9	ko:K01810	ko00010,ko00030,ko00500,ko00520,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00030,map00500,map00520,map01100,map01110,map01120,map01130,map01200	M00001,M00004,M00114	R02739,R02740,R03321	RC00376,RC00563	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	PGI
NFNHFNFO_03754	33035.JPJF01000043_gene938	4.82e-56	174.0	2CGVU@1|root,32S4Q@2|Bacteria,1V9YX@1239|Firmicutes,24NX8@186801|Clostridia,3Y0DQ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03755	33035.JPJF01000043_gene937	2.01e-160	450.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3XYV6@572511|Blautia	186801|Clostridia	T	COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain	phoP_1	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_03756	33035.JPJF01000043_gene936	0.0	1261.0	COG5002@1|root,COG5002@2|Bacteria,1UM03@1239|Firmicutes,24F2S@186801|Clostridia,3XYZD@572511|Blautia	186801|Clostridia	T	COG COG0642 Signal transduction histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_03757	537007.BLAHAN_04566	2.17e-246	679.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XYK4@572511|Blautia	186801|Clostridia	P	Belongs to the ABC transporter superfamily	ugpC_1	-	-	ko:K10112	ko02010,map02010	M00194,M00196,M00197,M00200,M00201,M00206,M00207,M00491,M00602,M00605,M00606	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1	-	-	ABC_tran,TOBE,TOBE_2
NFNHFNFO_03758	33035.JPJF01000043_gene934	2.48e-252	693.0	COG3835@1|root,COG3835@2|Bacteria,1TQWD@1239|Firmicutes,24ZMW@186801|Clostridia,3Y17S@572511|Blautia	186801|Clostridia	KT	PucR C-terminal helix-turn-helix domain	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	HTH_30
NFNHFNFO_03760	33035.JPJF01000003_gene1940	0.0	1466.0	COG1048@1|root,COG1048@2|Bacteria,1VTMM@1239|Firmicutes,25HJM@186801|Clostridia,3XYPZ@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score	ybhJ	-	4.2.1.3	ko:K01681	ko00020,ko00630,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,ko01210,ko01230,map00020,map00630,map00720,map01100,map01110,map01120,map01130,map01200,map01210,map01230	M00009,M00010,M00012,M00173,M00740	R01324,R01325,R01900	RC00497,RC00498,RC00618	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Aconitase,Aconitase_C
NFNHFNFO_03761	33035.JPJF01000003_gene1939	3.68e-133	380.0	COG0564@1|root,COG0564@2|Bacteria,1TX59@1239|Firmicutes,24HTV@186801|Clostridia,3XZWX@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 8.87	-	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NFNHFNFO_03762	33035.JPJF01000003_gene1938	2.77e-212	590.0	COG0628@1|root,COG0628@2|Bacteria,1TS4S@1239|Firmicutes,25CG4@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	AI-2E_transport
NFNHFNFO_03763	33035.JPJF01000003_gene1937	1.41e-230	643.0	COG1879@1|root,COG1879@2|Bacteria,1TS2M@1239|Firmicutes,248GT@186801|Clostridia,3Y29T@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NFNHFNFO_03765	33035.JPJF01000003_gene1935	0.0	1253.0	COG1269@1|root,COG1269@2|Bacteria,1TPTE@1239|Firmicutes,249YV@186801|Clostridia,3XYZB@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	ntpI	-	-	ko:K02123	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	V_ATPase_I
NFNHFNFO_03766	33035.JPJF01000003_gene1934	1.32e-96	282.0	COG0636@1|root,COG0636@2|Bacteria,1V786@1239|Firmicutes,24HBF@186801|Clostridia,3XZV1@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 9.99	ntpK	-	-	ko:K02124	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_C
NFNHFNFO_03767	33035.JPJF01000003_gene1933	1.43e-76	234.0	COG1390@1|root,COG1390@2|Bacteria,1VDHZ@1239|Firmicutes,24H5N@186801|Clostridia,3Y03R@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpE	-	-	ko:K02121	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_E
NFNHFNFO_03768	33035.JPJF01000003_gene1932	4.05e-219	606.0	COG1527@1|root,COG1527@2|Bacteria,1U6WZ@1239|Firmicutes,249XD@186801|Clostridia,3XYWC@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	ntpC	-	-	ko:K02119	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	vATP-synt_AC39
NFNHFNFO_03769	33035.JPJF01000003_gene1931	6.99e-65	198.0	COG1436@1|root,COG1436@2|Bacteria,1VAX7@1239|Firmicutes,24MXC@186801|Clostridia,3Y0EG@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	atpF	-	-	ko:K02122	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_F
NFNHFNFO_03770	33035.JPJF01000003_gene1930	0.0	1132.0	COG1155@1|root,COG1155@2|Bacteria,1TPGS@1239|Firmicutes,24882@186801|Clostridia,3XZT0@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit	ntpA	-	3.6.3.14,3.6.3.15	ko:K02117	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002,ko01000	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N,ATP-synt_ab_Xtn
NFNHFNFO_03771	33035.JPJF01000003_gene1929	0.0	892.0	COG1156@1|root,COG1156@2|Bacteria,1VSU1@1239|Firmicutes,2496H@186801|Clostridia,3XZIG@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit	atpB	-	-	ko:K02118	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_ab,ATP-synt_ab_N
NFNHFNFO_03772	33035.JPJF01000003_gene1928	1.78e-149	422.0	COG1394@1|root,COG1394@2|Bacteria,1TQ1Y@1239|Firmicutes,247TC@186801|Clostridia,3XZN7@572511|Blautia	186801|Clostridia	C	Produces ATP from ADP in the presence of a proton gradient across the membrane	atpD	-	-	ko:K02120	ko00190,ko01100,map00190,map01100	M00159	-	-	ko00000,ko00001,ko00002	3.A.2.2,3.A.2.3	-	-	ATP-synt_D
NFNHFNFO_03773	33035.JPJF01000003_gene1922	5.84e-221	610.0	COG0673@1|root,COG0673@2|Bacteria,1VW9R@1239|Firmicutes,24A75@186801|Clostridia	186801|Clostridia	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA
NFNHFNFO_03774	33035.JPJF01000003_gene1921	3.54e-214	597.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,248JF@186801|Clostridia	186801|Clostridia	G	Psort location Cytoplasmic, score	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
NFNHFNFO_03775	33035.JPJF01000003_gene1920	6.83e-305	833.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZGF@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_03776	33035.JPJF01000003_gene1919	4.66e-104	302.0	COG2110@1|root,COG2110@2|Bacteria,1TPCU@1239|Firmicutes,24ARG@186801|Clostridia,3Y0H8@572511|Blautia	186801|Clostridia	S	Appr-1'-p processing enzyme	ymdB	-	-	-	-	-	-	-	-	-	-	-	Macro
NFNHFNFO_03777	33035.JPJF01000003_gene1918	2.84e-236	655.0	COG2333@1|root,COG2333@2|Bacteria,1TS9U@1239|Firmicutes,249VR@186801|Clostridia,3XZI1@572511|Blautia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	ko:K02238	-	M00429	-	-	ko00000,ko00002,ko02044	3.A.11.1,3.A.11.2	-	-	Ada_Zn_binding,Lactamase_B
NFNHFNFO_03778	33035.JPJF01000003_gene1917	0.0	952.0	COG3012@1|root,COG4974@1|root,COG3012@2|Bacteria,COG4974@2|Bacteria,1UCSJ@1239|Firmicutes,24BGK@186801|Clostridia,3Y0NP@572511|Blautia	186801|Clostridia	L	Plasmid pRiA4b ORF-3-like protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3,SEC-C
NFNHFNFO_03779	33035.JPJF01000003_gene1916	1.08e-303	830.0	COG4905@1|root,COG4905@2|Bacteria,1TQUM@1239|Firmicutes,25CKD@186801|Clostridia,3XZ2R@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	ABC_trans_CmpB
NFNHFNFO_03780	33035.JPJF01000003_gene1915	2.76e-50	159.0	COG1609@1|root,COG1609@2|Bacteria,1VADF@1239|Firmicutes,24MXI@186801|Clostridia,3Y0IB@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	spoIIID	-	-	ko:K06283	-	-	-	-	ko00000,ko03000	-	-	-	SpoIIID
NFNHFNFO_03781	33035.JPJF01000003_gene1914	9.57e-299	817.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia,3XYQN@572511|Blautia	186801|Clostridia	V	MatE	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_03782	33035.JPJF01000003_gene1913	3.66e-311	848.0	COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3XZMP@572511|Blautia	186801|Clostridia	F	GMP synthase C terminal domain	-	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase
NFNHFNFO_03783	33035.JPJF01000003_gene1912	7.63e-100	296.0	COG1357@1|root,COG1357@2|Bacteria,1VAPB@1239|Firmicutes,24J9N@186801|Clostridia,3Y1PA@572511|Blautia	186801|Clostridia	S	Pentapeptide repeats (9 copies)	-	-	-	-	-	-	-	-	-	-	-	-	Pentapeptide,Pentapeptide_4
NFNHFNFO_03784	33035.JPJF01000003_gene1911	4.83e-201	558.0	COG0053@1|root,COG0053@2|Bacteria,1TSGY@1239|Firmicutes,2491V@186801|Clostridia,3XYZZ@572511|Blautia	186801|Clostridia	P	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family	fieF	-	-	-	-	-	-	-	-	-	-	-	Cation_efflux,ZT_dimer
NFNHFNFO_03785	33035.JPJF01000003_gene1910	0.0	1012.0	COG0519@1|root,COG0519@2|Bacteria,1TPG8@1239|Firmicutes,2487F@186801|Clostridia,3XZG5@572511|Blautia	186801|Clostridia	F	Catalyzes the synthesis of GMP from XMP	guaA	-	6.3.5.2	ko:K01951	ko00230,ko00983,ko01100,map00230,map00983,map01100	M00050	R01230,R01231,R08244	RC00010,RC00204	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase,GMP_synt_C,NAD_synthase,tRNA_Me_trans
NFNHFNFO_03786	1235793.C809_04689	2.32e-99	291.0	COG1396@1|root,COG1396@2|Bacteria,1V1JY@1239|Firmicutes,24HXG@186801|Clostridia,27KBW@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NFNHFNFO_03787	1235793.C809_03880	7.61e-32	111.0	2E5UB@1|root,30W41@2|Bacteria,1TUDJ@1239|Firmicutes,25N6J@186801|Clostridia,27Q0N@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03788	1235793.C809_03881	4.14e-252	692.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,247V6@186801|Clostridia,27IQ7@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Arm-DNA-bind_4,Phage_int_SAM_3,Phage_integrase
NFNHFNFO_03789	1235802.C823_06177	1.3e-65	200.0	2AQJ5@1|root,31FRY@2|Bacteria,1V6TG@1239|Firmicutes,24JD1@186801|Clostridia,25XJW@186806|Eubacteriaceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03790	397291.C804_06358	4.87e-244	673.0	COG3598@1|root,COG3598@2|Bacteria,1TU5N@1239|Firmicutes,247KK@186801|Clostridia,27JSQ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	AAA domain	-	-	-	-	-	-	-	-	-	-	-	-	AAA_25,PriCT_1,Prim-Pol
NFNHFNFO_03791	397287.C807_03078	3.07e-39	131.0	2CIZU@1|root,3323B@2|Bacteria,1VF1D@1239|Firmicutes,24QPV@186801|Clostridia,27Q4Y@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03792	476272.RUMHYD_03561	2.64e-28	105.0	2DZZU@1|root,32VPB@2|Bacteria,1VB1I@1239|Firmicutes,24PDU@186801|Clostridia,3Y0RA@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03793	397287.C807_03077	9.45e-181	518.0	COG3206@1|root,COG3206@2|Bacteria,1TR5K@1239|Firmicutes,24ARC@186801|Clostridia,27K2X@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Mob_Pre
NFNHFNFO_03794	411469.EUBHAL_00500	6.55e-302	831.0	COG0827@1|root,COG0827@2|Bacteria,1UXY1@1239|Firmicutes,24B3U@186801|Clostridia,25Y8Q@186806|Eubacteriaceae	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	2.1.1.72	ko:K07317	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	Eco57I,N6_Mtase
NFNHFNFO_03795	411469.EUBHAL_00501	2.25e-193	539.0	COG0827@1|root,COG0827@2|Bacteria,1UZYA@1239|Firmicutes,24CNN@186801|Clostridia,25YA8@186806|Eubacteriaceae	186801|Clostridia	L	BsuBI PstI restriction endonuclease domain protein	-	-	-	-	-	-	-	-	-	-	-	-	BsuBI_PstI_RE
NFNHFNFO_03797	1345695.CLSA_c19300	4.11e-15	85.9	COG0326@1|root,COG0326@2|Bacteria,1V148@1239|Firmicutes,24CNK@186801|Clostridia,36TVG@31979|Clostridiaceae	186801|Clostridia	O	Molecular chaperone. Has ATPase activity	-	-	-	ko:K04079	ko04141,ko04151,ko04217,ko04612,ko04621,ko04626,ko04657,ko04659,ko04914,ko04915,ko05200,ko05215,ko05418,map04141,map04151,map04217,map04612,map04621,map04626,map04657,map04659,map04914,map04915,map05200,map05215,map05418	-	-	-	ko00000,ko00001,ko01009,ko03029,ko03051,ko03110,ko04131,ko04147	-	-	-	HATPase_c_3
NFNHFNFO_03798	443144.GM21_0301	1.42e-148	445.0	COG1032@1|root,COG1032@2|Bacteria,1NG4M@1224|Proteobacteria	1224|Proteobacteria	C	radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03799	1235798.C817_03833	4.62e-68	220.0	COG3843@1|root,COG3843@2|Bacteria,1TPRX@1239|Firmicutes,2481D@186801|Clostridia,27V74@189330|Dorea	186801|Clostridia	U	Relaxase/Mobilisation nuclease domain	-	-	-	-	-	-	-	-	-	-	-	-	Relaxase
NFNHFNFO_03800	1235798.C817_03834	2.36e-216	597.0	COG5504@1|root,COG5504@2|Bacteria,1TT7P@1239|Firmicutes,24C0E@186801|Clostridia	186801|Clostridia	O	Predicted Zn-dependent protease (DUF2268)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2268
NFNHFNFO_03801	1235798.C817_03835	1.06e-181	505.0	COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,24AD8@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	mta	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase,MerR_1,TipAS
NFNHFNFO_03802	1235798.C817_03893	2.1e-180	503.0	COG0789@1|root,COG0789@2|Bacteria,1TRYB@1239|Firmicutes,24GSY@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Cass2,GyrI-like,MerR_1
NFNHFNFO_03803	33035.JPJF01000016_gene3899	0.0	931.0	COG1574@1|root,COG1574@2|Bacteria,1TQ6G@1239|Firmicutes,24A5F@186801|Clostridia,3XZ3F@572511|Blautia	186801|Clostridia	S	Amidohydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_3
NFNHFNFO_03804	33035.JPJF01000016_gene3900	0.0	993.0	COG0443@1|root,COG0443@2|Bacteria,1TP1J@1239|Firmicutes,248QV@186801|Clostridia,3XZDF@572511|Blautia	186801|Clostridia	O	Heat shock 70 kDa protein	-	-	-	-	-	-	-	-	-	-	-	-	HSP70
NFNHFNFO_03805	33035.JPJF01000016_gene3901	6.45e-313	885.0	COG0457@1|root,COG0457@2|Bacteria,1UKYH@1239|Firmicutes,24B57@186801|Clostridia	186801|Clostridia	O	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
NFNHFNFO_03806	33035.JPJF01000016_gene3901	4.79e-273	779.0	COG0457@1|root,COG0457@2|Bacteria,1UKYH@1239|Firmicutes,24B57@186801|Clostridia	186801|Clostridia	O	tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_1,TPR_12,TPR_16,TPR_19,TPR_2,TPR_8
NFNHFNFO_03807	33035.JPJF01000016_gene3902	0.0	897.0	COG2199@1|root,COG2199@2|Bacteria,1V0N3@1239|Firmicutes,24FMU@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	7TMR-DISM_7TM,GGDEF
NFNHFNFO_03808	33035.JPJF01000016_gene3904	6.41e-91	267.0	2CGYA@1|root,345S7@2|Bacteria,1UI0A@1239|Firmicutes,24S83@186801|Clostridia	186801|Clostridia	S	CheW-like domain	-	-	-	-	-	-	-	-	-	-	-	-	CheW
NFNHFNFO_03809	33035.JPJF01000016_gene3905	7.5e-33	125.0	COG0643@1|root,COG0643@2|Bacteria,1TPMS@1239|Firmicutes,24858@186801|Clostridia	186801|Clostridia	T	Signal transducing histidine kinase homodimeric	-	-	2.7.13.3	ko:K03407	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022,ko02035	-	-	-	CheW,H-kinase_dim,HATPase_c,Hpt,P2
NFNHFNFO_03810	33035.JPJF01000016_gene3909	8.92e-167	484.0	COG0840@1|root,COG0840@2|Bacteria,1TP5A@1239|Firmicutes,247S3@186801|Clostridia	186801|Clostridia	NT	methyl-accepting chemotaxis protein	-	-	-	ko:K03406	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko02035	-	-	-	4HB_MCP_1,HAMP,MCPsignal
NFNHFNFO_03811	33035.JPJF01000016_gene3910	3.47e-73	220.0	COG2204@1|root,COG2204@2|Bacteria,1UHXE@1239|Firmicutes,25E6A@186801|Clostridia	186801|Clostridia	T	response regulator receiver	cheY	-	-	ko:K03413	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko02022,ko02035	-	-	-	Response_reg
NFNHFNFO_03812	33035.JPJF01000016_gene3911	5.76e-116	337.0	COG1352@1|root,COG1352@2|Bacteria,1TPD8@1239|Firmicutes,24AQJ@186801|Clostridia	186801|Clostridia	NT	PFAM MCP methyltransferase, CheR-type	cheR	-	2.1.1.80	ko:K00575	ko02020,ko02030,map02020,map02030	-	-	-	ko00000,ko00001,ko01000,ko02035	-	-	-	CheR,CheR_N
NFNHFNFO_03813	33035.JPJF01000016_gene3912	1.96e-45	150.0	2DCSZ@1|root,2ZF86@2|Bacteria,1W408@1239|Firmicutes,24T8Z@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03814	33035.JPJF01000016_gene3913	6.2e-60	187.0	29VD7@1|root,30GTW@2|Bacteria,1UGMV@1239|Firmicutes,24V4J@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03815	33035.JPJF01000016_gene3914	0.0	1645.0	COG0495@1|root,COG0495@2|Bacteria,1TP0Y@1239|Firmicutes,2484Y@186801|Clostridia,3XZ20@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	leuS	-	6.1.1.4	ko:K01869	ko00970,map00970	M00359,M00360	R03657	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	Anticodon_1,tRNA-synt_1,tRNA-synt_1_2
NFNHFNFO_03816	33035.JPJF01000016_gene3915	0.0	995.0	2BW99@1|root,2Z7PD@2|Bacteria,1TQFA@1239|Firmicutes,249NB@186801|Clostridia,3XYY5@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03817	33035.JPJF01000016_gene3916	0.0	1356.0	COG0480@1|root,COG0480@2|Bacteria,1TPWN@1239|Firmicutes,247N4@186801|Clostridia,3XZ5X@572511|Blautia	186801|Clostridia	J	translation elongation factor G	fusA2	-	-	ko:K02355	-	-	-	-	ko00000,ko03012,ko03029	-	-	-	EFG_C,EFG_II,EFG_IV,GTP_EFTU,GTP_EFTU_D2
NFNHFNFO_03818	33035.JPJF01000016_gene3917	1.7e-261	716.0	COG0287@1|root,COG0287@2|Bacteria,1TPXG@1239|Firmicutes,248KX@186801|Clostridia,3XZI7@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	tyrA	-	1.3.1.12	ko:K04517	ko00400,ko00401,ko01100,ko01110,ko01130,ko01230,map00400,map00401,map01100,map01110,map01130,map01230	M00025	R01728	RC00125	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,PDH
NFNHFNFO_03819	33035.JPJF01000016_gene3918	3.23e-261	721.0	COG0128@1|root,COG0128@2|Bacteria,1TPIH@1239|Firmicutes,2488G@186801|Clostridia,3XZCI@572511|Blautia	186801|Clostridia	E	Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate	aroA	-	2.5.1.19	ko:K00800	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R03460	RC00350	ko00000,ko00001,ko00002,ko01000	-	-	-	EPSP_synthase
NFNHFNFO_03820	33035.JPJF01000016_gene3919	7.34e-129	366.0	COG1309@1|root,COG1309@2|Bacteria,1UYIP@1239|Firmicutes,249K5@186801|Clostridia,3XZUQ@572511|Blautia	186801|Clostridia	K	Transcriptional regulator C-terminal region	-	-	-	-	-	-	-	-	-	-	-	-	TetR_C_8,TetR_N
NFNHFNFO_03821	33035.JPJF01000016_gene3920	0.0	1185.0	COG4716@1|root,COG4716@2|Bacteria,1TQZ6@1239|Firmicutes,248TZ@186801|Clostridia,3XZ82@572511|Blautia	186801|Clostridia	S	MCRA family	-	-	4.2.1.53	ko:K10254	-	-	-	-	ko00000,ko01000	-	-	-	MCRA
NFNHFNFO_03822	1292035.H476_1804	1.82e-119	379.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,25SK2@186804|Peptostreptococcaceae	186801|Clostridia	V	FtsX-like permease family	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NFNHFNFO_03823	1301100.HG529315_gene453	6.54e-133	382.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,36DTD@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_03824	1292035.H476_1806	1.37e-90	281.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,25UNX@186804|Peptostreptococcaceae	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
NFNHFNFO_03825	1301100.HG529315_gene451	1.28e-90	272.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,36EMS@31979|Clostridiaceae	186801|Clostridia	T	response regulator	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_03826	1121115.AXVN01000108_gene623	4.29e-128	391.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,25B1H@186801|Clostridia,3Y2A1@572511|Blautia	186801|Clostridia	KT	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_03827	592026.GCWU0000282_002970	9.39e-151	454.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,24ET6@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
NFNHFNFO_03828	33035.JPJF01000015_gene4964	0.0	1656.0	COG0457@1|root,COG3629@1|root,COG0457@2|Bacteria,COG3629@2|Bacteria,1VA4B@1239|Firmicutes,24P3V@186801|Clostridia	186801|Clostridia	T	Tetratricopeptide repeats	-	-	-	-	-	-	-	-	-	-	-	-	TPR_2
NFNHFNFO_03829	33035.JPJF01000015_gene4965	0.0	970.0	COG2986@1|root,COG2986@2|Bacteria,1TPCW@1239|Firmicutes,247XP@186801|Clostridia	186801|Clostridia	E	Histidine ammonia-lyase	hutH	-	4.3.1.3	ko:K01745	ko00340,ko01100,map00340,map01100	M00045	R01168	RC00361	ko00000,ko00001,ko00002,ko01000	-	-	-	Lyase_aromatic
NFNHFNFO_03830	33035.JPJF01000015_gene4966	1.82e-282	776.0	COG3314@1|root,COG3314@2|Bacteria,1TR35@1239|Firmicutes,249N2@186801|Clostridia	186801|Clostridia	S	domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Gate
NFNHFNFO_03831	33035.JPJF01000015_gene4967	0.0	1269.0	COG0446@1|root,COG1902@1|root,COG0446@2|Bacteria,COG1902@2|Bacteria,1TPM6@1239|Firmicutes,247V1@186801|Clostridia,3XZ6J@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	1.3.1.31	ko:K10797	ko00360,ko01120,map00360,map01120	-	R02252	RC00669	ko00000,ko00001,ko01000	-	-	-	Oxidored_FMN,Pyr_redox_2
NFNHFNFO_03832	33035.JPJF01000015_gene4968	0.0	1273.0	COG2987@1|root,COG2987@2|Bacteria,1TPZ9@1239|Firmicutes,247YS@186801|Clostridia,3Y156@572511|Blautia	186801|Clostridia	E	Urocanase C-terminal domain	-	-	4.2.1.49	ko:K01712	ko00340,ko01100,map00340,map01100	M00045	R02914	RC00804	ko00000,ko00001,ko00002,ko01000	-	-	-	Urocanase,Urocanase_C,Urocanase_N
NFNHFNFO_03833	33035.JPJF01000015_gene4969	2.64e-46	150.0	COG3743@1|root,COG3743@2|Bacteria,1VEZU@1239|Firmicutes,24RST@186801|Clostridia	186801|Clostridia	S	tfoX C-terminal domain	-	-	-	ko:K07343	-	-	-	-	ko00000	-	-	-	TfoX_C
NFNHFNFO_03834	33035.JPJF01000015_gene4970	3.06e-57	179.0	COG0221@1|root,COG0221@2|Bacteria,1VB6Q@1239|Firmicutes,24NZI@186801|Clostridia	186801|Clostridia	C	Inorganic pyrophosphatase	-	-	3.6.1.1	ko:K01507	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	NUDIX,Pyrophosphatase
NFNHFNFO_03835	33035.JPJF01000015_gene4971	6.63e-97	285.0	COG0406@1|root,COG0406@2|Bacteria,1V8SK@1239|Firmicutes,24KJ4@186801|Clostridia	186801|Clostridia	G	Phosphoglycerate mutase family	-	-	-	-	-	-	-	-	-	-	-	-	His_Phos_1
NFNHFNFO_03836	742740.HMPREF9474_01560	4.36e-177	505.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,2492H@186801|Clostridia,2206M@1506553|Lachnoclostridium	186801|Clostridia	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
NFNHFNFO_03837	742740.HMPREF9474_01559	1.29e-240	672.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,248UK@186801|Clostridia,222GZ@1506553|Lachnoclostridium	186801|Clostridia	S	Short chain fatty acid transporter	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
NFNHFNFO_03838	658086.HMPREF0994_05392	0.0	1120.0	COG3666@1|root,COG3666@2|Bacteria,1TQQ9@1239|Firmicutes,24AG9@186801|Clostridia,27K17@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1_6,DUF772
NFNHFNFO_03843	365044.Pnap_2529	2.7e-11	65.5	COG4227@1|root,COG4227@2|Bacteria,1MU8I@1224|Proteobacteria,2VMTV@28216|Betaproteobacteria,4AE8Y@80864|Comamonadaceae	28216|Betaproteobacteria	L	Domain of unknown function (DUF1738)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1738,Toprim_3,Toprim_4
NFNHFNFO_03844	610130.Closa_2253	5.47e-240	678.0	COG4166@1|root,COG4166@2|Bacteria,1TNYQ@1239|Firmicutes,25E4B@186801|Clostridia,21YUG@1506553|Lachnoclostridium	186801|Clostridia	E	PFAM extracellular solute-binding protein family 5	oppA	-	-	ko:K15580	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	SBP_bac_5
NFNHFNFO_03845	1298920.KI911353_gene2530	1.63e-171	484.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,21ZW9@1506553|Lachnoclostridium	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	oppB	-	-	ko:K15581	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1
NFNHFNFO_03846	610130.Closa_2251	8.4e-144	414.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,21YK7@1506553|Lachnoclostridium	186801|Clostridia	EP	N-terminal TM domain of oligopeptide transport permease C	oppC	-	-	ko:K02034,ko:K15582	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	BPD_transp_1,OppC_N
NFNHFNFO_03847	1298920.KI911353_gene2528	4.19e-174	493.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,21XZZ@1506553|Lachnoclostridium	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NFNHFNFO_03848	1304866.K413DRAFT_3888	3.6e-164	467.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,36EGD@31979|Clostridiaceae	186801|Clostridia	P	Belongs to the ABC transporter superfamily	-	-	-	ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NFNHFNFO_03849	658086.HMPREF0994_01129	1.01e-256	710.0	COG3669@1|root,COG3669@2|Bacteria,1TQH2@1239|Firmicutes,24B8Y@186801|Clostridia,27JFC@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Alpha-L-fucosidase	-	-	3.2.1.51	ko:K01206	ko00511,map00511	-	-	-	ko00000,ko00001,ko01000,ko04147	-	GH29	-	Alpha_L_fucos
NFNHFNFO_03850	1121115.AXVN01000028_gene213	1.8e-135	389.0	COG1349@1|root,COG1349@2|Bacteria,1TSU1@1239|Firmicutes,25C4E@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator, DeoR	-	-	-	ko:K02444	-	-	-	-	ko00000,ko03000	-	-	-	DeoRC,HTH_DeoR
NFNHFNFO_03851	180332.JTGN01000001_gene4703	8.52e-172	498.0	COG0260@1|root,COG0260@2|Bacteria,1TPJZ@1239|Firmicutes,248KF@186801|Clostridia	186801|Clostridia	E	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides	pepA	-	3.4.11.1	ko:K01255	ko00480,ko01100,map00480,map01100	-	R00899,R04951	RC00096,RC00141	ko00000,ko00001,ko01000,ko01002	-	-	-	Peptidase_M17,Peptidase_M17_N
NFNHFNFO_03852	457412.RSAG_02251	5.03e-122	354.0	COG3142@1|root,COG3142@2|Bacteria,1UYI8@1239|Firmicutes,247QB@186801|Clostridia,3WIQQ@541000|Ruminococcaceae	186801|Clostridia	P	Participates in the control of copper homeostasis	cutC	-	-	ko:K06201	-	-	-	-	ko00000	-	-	-	CutC
NFNHFNFO_03853	1121115.AXVN01000028_gene215	4.99e-317	895.0	COG1305@1|root,COG1305@2|Bacteria,1TQGN@1239|Firmicutes,249YH@186801|Clostridia,3Y18M@572511|Blautia	186801|Clostridia	E	Transglutaminase-like superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Transglut_core
NFNHFNFO_03854	1280668.ATVT01000005_gene1963	3.18e-101	301.0	COG0310@1|root,COG0310@2|Bacteria,1TPEN@1239|Firmicutes,248S9@186801|Clostridia,4BW72@830|Butyrivibrio	186801|Clostridia	P	PDGLE domain	cbiM2	-	-	ko:K02007	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiM,PDGLE
NFNHFNFO_03855	97139.C824_01342	4.17e-09	56.2	COG0619@1|root,COG0619@2|Bacteria,1U6XW@1239|Firmicutes,24EV0@186801|Clostridia,36FJU@31979|Clostridiaceae	186801|Clostridia	P	Cobalt ABC transporter, permease	cbiQ	-	-	ko:K02008	ko02010,map02010	M00245,M00246	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.18,3.A.1.22,3.A.1.23	-	-	CbiQ
NFNHFNFO_03856	33035.JPJF01000041_gene358	0.0	1362.0	COG0855@1|root,COG0855@2|Bacteria,1TNZM@1239|Firmicutes,248XY@186801|Clostridia,3XZ98@572511|Blautia	186801|Clostridia	H	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)	ppk	-	2.7.4.1	ko:K00937	ko00190,ko03018,map00190,map03018	-	-	-	ko00000,ko00001,ko01000,ko03019	-	-	-	PP_kinase,PP_kinase_C,PP_kinase_N
NFNHFNFO_03857	33035.JPJF01000041_gene357	0.0	970.0	COG0248@1|root,COG0248@2|Bacteria,1TS3I@1239|Firmicutes,248EW@186801|Clostridia,3XYWZ@572511|Blautia	186801|Clostridia	FP	Ppx/GppA phosphatase family	ppx	-	3.6.1.11,3.6.1.40	ko:K01524	ko00230,map00230	-	R03409	RC00002	ko00000,ko00001,ko01000	-	-	-	HD,Ppx-GppA
NFNHFNFO_03858	33035.JPJF01000041_gene356	2.76e-163	458.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UUV8@1239|Firmicutes,25KD0@186801|Clostridia,3Y1YD@572511|Blautia	186801|Clostridia	T	cheY-homologous receiver domain	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg
NFNHFNFO_03859	33035.JPJF01000041_gene355	2.59e-184	514.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_03860	33035.JPJF01000041_gene354	1.54e-208	577.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_03861	33035.JPJF01000041_gene353	3.09e-303	829.0	COG1653@1|root,COG1653@2|Bacteria,1TQ75@1239|Firmicutes,24BNJ@186801|Clostridia	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_03862	33035.JPJF01000041_gene347	7.69e-248	696.0	COG2508@1|root,COG2508@2|Bacteria	2|Bacteria	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NFNHFNFO_03863	33035.JPJF01000041_gene346	0.0	872.0	COG2508@1|root,COG2508@2|Bacteria,1VK8J@1239|Firmicutes	1239|Firmicutes	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NFNHFNFO_03864	33035.JPJF01000041_gene345	3.51e-249	689.0	COG0477@1|root,COG2814@2|Bacteria	2|Bacteria	EGP	Major facilitator Superfamily	uhpT	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_Mycoplasma
NFNHFNFO_03865	33035.JPJF01000041_gene344	6.02e-247	677.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia,3Y1E6@572511|Blautia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_03867	1437608.BBIA_0602	2.26e-97	291.0	2DB8R@1|root,2Z7SP@2|Bacteria,2GYVE@201174|Actinobacteria,4D1QK@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03868	33035.JPJF01000009_gene1540	1.36e-111	333.0	COG3173@1|root,COG3173@2|Bacteria,1U6NE@1239|Firmicutes,2489R@186801|Clostridia	186801|Clostridia	S	Phosphotransferase enzyme family	-	-	-	-	-	-	-	-	-	-	-	-	APH
NFNHFNFO_03869	33035.JPJF01000009_gene1541	9.71e-136	404.0	COG0534@1|root,COG0534@2|Bacteria,1TPFM@1239|Firmicutes,247J9@186801|Clostridia	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_03870	1122925.KB895381_gene3896	7.85e-81	257.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1V1RQ@1239|Firmicutes,4HJZQ@91061|Bacilli,26UJ4@186822|Paenibacillaceae	91061|Bacilli	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18
NFNHFNFO_03871	33035.JPJF01000046_gene1015	3.54e-54	172.0	COG1670@1|root,COG2207@1|root,COG1670@2|Bacteria,COG2207@2|Bacteria,1UUVD@1239|Firmicutes,24XA1@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_AraC
NFNHFNFO_03872	33035.JPJF01000046_gene1014	3.11e-121	345.0	COG1373@1|root,COG1373@2|Bacteria	2|Bacteria	V	ATPase (AAA superfamily	-	-	-	ko:K07133	-	-	-	-	ko00000	-	-	-	AAA_14
NFNHFNFO_03873	33035.JPJF01000046_gene1013	0.0	892.0	COG3867@1|root,COG3867@2|Bacteria,1TQDZ@1239|Firmicutes,24CPM@186801|Clostridia,3Y15B@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolase family 53	-	-	3.2.1.89	ko:K01224	-	-	-	-	ko00000,ko01000	-	-	-	Glyco_hydro_53,RicinB_lectin_2
NFNHFNFO_03874	33035.JPJF01000046_gene1012	0.0	1696.0	COG3250@1|root,COG3250@2|Bacteria,1TPK7@1239|Firmicutes,247VE@186801|Clostridia,3XZF6@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolase family 2, sugar binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	DUF4982,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFNHFNFO_03875	658088.HMPREF0987_02093	2.77e-228	640.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia,27IIX@186928|unclassified Lachnospiraceae	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_03876	33035.JPJF01000046_gene1010	9.9e-195	543.0	COG2169@1|root,COG2169@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	3.2.2.21	ko:K13529,ko:K15051	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03000,ko03400	-	-	-	Ada_Zn_binding,AlkA_N,AraC_binding,Arabinose_bd,Cupin_2,Endonuclea_NS_2,HTH_18
NFNHFNFO_03877	33035.JPJF01000025_gene2616	7.29e-135	389.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1V8XZ@1239|Firmicutes,24DFZ@186801|Clostridia	186801|Clostridia	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	GyrI-like,HTH_18
NFNHFNFO_03878	742733.HMPREF9469_05983	1.42e-233	651.0	COG4974@1|root,COG4974@2|Bacteria,1TQST@1239|Firmicutes,247YT@186801|Clostridia,21YKW@1506553|Lachnoclostridium	186801|Clostridia	L	zinc-finger binding domain of transposase IS66	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
NFNHFNFO_03879	411902.CLOBOL_07347	1.1e-50	172.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24C2K@186801|Clostridia,2206K@1506553|Lachnoclostridium	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NFNHFNFO_03881	33035.JPJF01000035_gene3482	1.19e-169	479.0	COG0697@1|root,COG0697@2|Bacteria,1TRKE@1239|Firmicutes,249RU@186801|Clostridia	186801|Clostridia	EG	metabolite transporter	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_03882	553973.CLOHYLEM_05791	2.75e-78	256.0	COG2199@1|root,COG2199@2|Bacteria,1U78Z@1239|Firmicutes,24BM3@186801|Clostridia,21Z95@1506553|Lachnoclostridium	186801|Clostridia	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,dCache_1
NFNHFNFO_03883	33035.JPJF01000035_gene3481	1.21e-297	815.0	COG1653@1|root,COG1653@2|Bacteria,1TPBS@1239|Firmicutes,24K16@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_03884	33035.JPJF01000035_gene3480	0.0	1103.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,25KCW@186801|Clostridia,3Y11X@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
NFNHFNFO_03885	33035.JPJF01000035_gene3479	0.0	968.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3XZ1E@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_03886	33035.JPJF01000035_gene3478	3.92e-306	835.0	COG1653@1|root,COG1653@2|Bacteria,1UZFS@1239|Firmicutes	1239|Firmicutes	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027,ko:K10117	ko02010,map02010	M00196,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_03887	33035.JPJF01000035_gene3477	3.22e-216	597.0	COG1175@1|root,COG1175@2|Bacteria,1TTAF@1239|Firmicutes,24AHK@186801|Clostridia,3XZH7@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_03888	33035.JPJF01000035_gene3476	3.48e-168	473.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia,3XZGR@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_03889	33035.JPJF01000035_gene3475	0.0	1427.0	COG3345@1|root,COG3345@2|Bacteria,1TSZB@1239|Firmicutes,247VV@186801|Clostridia	186801|Clostridia	G	alpha-galactosidase	-	-	3.2.1.22	ko:K07407	ko00052,ko00561,ko00600,ko00603,map00052,map00561,map00600,map00603	-	R01101,R01103,R01104,R01194,R01329,R02926,R03634,R04019,R04470,R05549,R05961,R06091	RC00049,RC00059,RC00451	ko00000,ko00001,ko01000	-	-	-	Melibiase
NFNHFNFO_03890	33035.JPJF01000032_gene2188	8.79e-317	866.0	COG2211@1|root,COG2211@2|Bacteria,1UJ7Q@1239|Firmicutes,24DJ1@186801|Clostridia	186801|Clostridia	G	TIGRFAM sugar (Glycoside-Pentoside-Hexuronide) transporter	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_03891	33035.JPJF01000032_gene2189	9.65e-241	660.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia,3Y1E6@572511|Blautia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_03892	33035.JPJF01000032_gene2190	1.83e-298	814.0	COG0112@1|root,COG0112@2|Bacteria,1TQVM@1239|Firmicutes,248W5@186801|Clostridia,3XYZQ@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism	glyA	-	2.1.2.1	ko:K00600	ko00260,ko00460,ko00630,ko00670,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko01523,map00260,map00460,map00630,map00670,map00680,map01100,map01110,map01120,map01130,map01200,map01230,map01523	M00140,M00141,M00346,M00532	R00945,R09099	RC00022,RC00112,RC01583,RC02958	ko00000,ko00001,ko00002,ko01000	-	-	-	SHMT
NFNHFNFO_03894	33035.JPJF01000032_gene2191	3.73e-208	576.0	COG0179@1|root,COG0179@2|Bacteria,1TQDQ@1239|Firmicutes,248AJ@186801|Clostridia	186801|Clostridia	Q	fumarylacetoacetate (FAA) hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	FAA_hydrolase
NFNHFNFO_03895	33035.JPJF01000032_gene2192	8.26e-90	264.0	COG1522@1|root,COG1522@2|Bacteria,1V3MI@1239|Firmicutes,24I1I@186801|Clostridia,3Y00A@572511|Blautia	186801|Clostridia	K	helix_turn_helix ASNC type	-	-	-	ko:K03719	-	-	-	-	ko00000,ko03000,ko03036	-	-	-	AsnC_trans_reg,HTH_24,HTH_AsnC-type
NFNHFNFO_03896	33035.JPJF01000032_gene2193	2.17e-214	593.0	COG0010@1|root,COG0010@2|Bacteria,1TP2A@1239|Firmicutes,2493V@186801|Clostridia,3XYTI@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Arginase
NFNHFNFO_03897	33035.JPJF01000032_gene2194	1.53e-148	419.0	COG1994@1|root,COG1994@2|Bacteria,1V6D4@1239|Firmicutes,24K0D@186801|Clostridia	186801|Clostridia	S	Peptidase M50	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M50
NFNHFNFO_03898	33035.JPJF01000032_gene2195	1.22e-89	265.0	2CAVT@1|root,304CC@2|Bacteria,1V4J6@1239|Firmicutes,24HQA@186801|Clostridia,3Y07W@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF2798
NFNHFNFO_03900	476272.RUMHYD_00139	1.24e-271	754.0	COG0591@1|root,COG0591@2|Bacteria,1TPVE@1239|Firmicutes,248NQ@186801|Clostridia,3XYPP@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 10.00	putP	-	-	ko:K03307,ko:K11928	-	-	-	-	ko00000,ko02000	2.A.21,2.A.21.2	-	-	SSF
NFNHFNFO_03901	650150.ERH_1292	4.9e-131	382.0	28MKK@1|root,2ZAWR@2|Bacteria,1UYAT@1239|Firmicutes,3VSD5@526524|Erysipelotrichia	526524|Erysipelotrichia	S	Putative viral replication protein	-	-	-	-	-	-	-	-	-	-	-	-	RNA_helicase,Viral_Rep
NFNHFNFO_03908	1123075.AUDP01000005_gene914	3.76e-70	223.0	COG5012@1|root,COG5012@2|Bacteria	2|Bacteria	T	cobalamin binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03910	180332.JTGN01000018_gene75	1.83e-65	214.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24C14@186801|Clostridia	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_03911	1123075.AUDP01000005_gene913	6.57e-117	350.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24C14@186801|Clostridia,3WHJ4@541000|Ruminococcaceae	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_03912	1158610.UC3_00386	9.7e-22	99.8	COG2207@1|root,COG2207@2|Bacteria,1V2EN@1239|Firmicutes,4HG9I@91061|Bacilli,4B0Z0@81852|Enterococcaceae	91061|Bacilli	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_03913	33035.JPJF01000024_gene3185	8.43e-283	776.0	COG1757@1|root,COG1757@2|Bacteria,1TQPI@1239|Firmicutes,2495U@186801|Clostridia,3XZ6V@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score 10.00	mleN_2	-	-	-	-	-	-	-	-	-	-	-	Na_H_antiporter
NFNHFNFO_03914	33035.JPJF01000024_gene3184	0.0	917.0	COG0015@1|root,COG0015@2|Bacteria,1TPMM@1239|Firmicutes,2485N@186801|Clostridia,3XZ1Q@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purB	-	4.3.2.2	ko:K01756	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559	RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	ADSL_C,Lyase_1
NFNHFNFO_03915	33035.JPJF01000024_gene3183	7.71e-166	464.0	COG0152@1|root,COG0152@2|Bacteria,1TP11@1239|Firmicutes,2483I@186801|Clostridia,3XZ17@572511|Blautia	186801|Clostridia	F	Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase	purC	-	4.3.2.2,6.3.2.6	ko:K01756,ko:K01923	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048,M00049	R01083,R04559,R04591	RC00064,RC00162,RC00379,RC00444,RC00445	ko00000,ko00001,ko00002,ko01000	-	-	-	SAICAR_synt
NFNHFNFO_03916	33035.JPJF01000024_gene3182	3.52e-178	497.0	2B4WY@1|root,31XPQ@2|Bacteria,1V739@1239|Firmicutes,24D1P@186801|Clostridia,3Y01X@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	TPR_8
NFNHFNFO_03917	33035.JPJF01000024_gene3181	7.03e-309	840.0	28MVQ@1|root,2ZB38@2|Bacteria,1UUTH@1239|Firmicutes,24AV8@186801|Clostridia,3XZBP@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03918	33035.JPJF01000024_gene3180	0.0	2190.0	2C1EE@1|root,2Z86R@2|Bacteria,1TS39@1239|Firmicutes,24ABS@186801|Clostridia,3XZIB@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	Rnd	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03919	33035.JPJF01000024_gene3179	7.77e-260	712.0	COG0079@1|root,COG0079@2|Bacteria,1TP5D@1239|Firmicutes,248Q0@186801|Clostridia,3XYRN@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	hisC	-	4.1.1.81	ko:K04720	ko00860,map00860	-	R06530	RC00517	ko00000,ko00001,ko01000	-	-	-	Aminotran_1_2
NFNHFNFO_03928	33035.JPJF01000037_gene2900	5.03e-111	321.0	COG1595@1|root,COG1595@2|Bacteria,1V55A@1239|Firmicutes,24GME@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_03929	33035.JPJF01000037_gene2901	1.96e-192	540.0	29WCT@1|root,30HYG@2|Bacteria,1TYPB@1239|Firmicutes,258RC@186801|Clostridia,3Y1W1@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NFNHFNFO_03930	33035.JPJF01000037_gene2902	1.91e-190	528.0	28P0Q@1|root,2ZBX8@2|Bacteria,1V22P@1239|Firmicutes,248XV@186801|Clostridia,3XZCT@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03931	33035.JPJF01000037_gene2903	5.12e-303	829.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XZAY@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.99	mepA_10	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_03932	33035.JPJF01000037_gene2904	4.26e-51	163.0	2BNPY@1|root,32HD2@2|Bacteria,1UFV1@1239|Firmicutes,25MSW@186801|Clostridia,3Y1Y7@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03933	33035.JPJF01000037_gene2905	2.91e-315	858.0	COG2873@1|root,COG2873@2|Bacteria,1VYCY@1239|Firmicutes,247XK@186801|Clostridia,3XZIV@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	metY	-	2.5.1.49	ko:K01740	ko00270,ko01100,map00270,map01100	-	R01287,R04859	RC00020,RC02821,RC02848	ko00000,ko00001,ko01000	-	-	-	Cys_Met_Meta_PP
NFNHFNFO_03934	33035.JPJF01000037_gene2906	1.03e-114	330.0	COG2519@1|root,COG2519@2|Bacteria,1V6VU@1239|Firmicutes,24JEE@186801|Clostridia,3XZYS@572511|Blautia	186801|Clostridia	J	Putative rRNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	rRNA_methylase
NFNHFNFO_03935	33035.JPJF01000037_gene2907	8.19e-186	519.0	COG2385@1|root,COG2385@2|Bacteria,1TQSI@1239|Firmicutes,249H0@186801|Clostridia,3Y01U@572511|Blautia	186801|Clostridia	D	COG COG2385 Sporulation protein and related proteins	spoIID	-	-	ko:K06381	-	-	-	-	ko00000	-	-	-	SpoIID
NFNHFNFO_03937	33035.JPJF01000037_gene2908	3.43e-130	376.0	COG0739@1|root,COG0739@2|Bacteria,1VATR@1239|Firmicutes,24N76@186801|Clostridia,3Y09E@572511|Blautia	186801|Clostridia	M	COG COG0739 Membrane proteins related to metalloendopeptidases	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M23
NFNHFNFO_03940	33035.JPJF01000073_gene4416	8.94e-227	624.0	COG0407@1|root,COG0407@2|Bacteria,1UZD2@1239|Firmicutes,24C43@186801|Clostridia,3Y1E6@572511|Blautia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_03941	33035.JPJF01000073_gene4415	8.17e-302	826.0	COG2211@1|root,COG2211@2|Bacteria,1UJ7Q@1239|Firmicutes,24DJ1@186801|Clostridia	186801|Clostridia	G	TIGRFAM sugar (Glycoside-Pentoside-Hexuronide) transporter	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_03942	33035.JPJF01000073_gene4414	0.0	947.0	COG2508@1|root,COG2508@2|Bacteria,1VIT3@1239|Firmicutes,24JXW@186801|Clostridia,3Y0T9@572511|Blautia	186801|Clostridia	QT	PucR C-terminal helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_30
NFNHFNFO_03943	33035.JPJF01000073_gene4413	3.04e-203	563.0	COG0657@1|root,COG0657@2|Bacteria,1UZ7B@1239|Firmicutes,25B2C@186801|Clostridia	186801|Clostridia	I	Psort location Cytoplasmic, score	-	-	3.1.1.83	ko:K14731	ko00903,ko00930,ko01220,map00903,map00930,map01220	-	R03751,R06390,R06391,R06392,R06393	RC00713,RC00983,RC01505	ko00000,ko00001,ko01000	-	-	-	Abhydrolase_3
NFNHFNFO_03944	33035.JPJF01000073_gene4412	8.88e-305	833.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia,3XZ6F@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
NFNHFNFO_03945	33035.JPJF01000073_gene4411	2.24e-148	419.0	2EFH0@1|root,2ZA40@2|Bacteria,1V0W1@1239|Firmicutes,24BY4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03946	33035.JPJF01000092_gene287	9.66e-290	793.0	COG2211@1|root,COG2211@2|Bacteria,1URUG@1239|Firmicutes,248SK@186801|Clostridia	186801|Clostridia	G	PFAM Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NFNHFNFO_03947	33035.JPJF01000051_gene767	3.21e-203	564.0	COG2207@1|root,COG2207@2|Bacteria,1V579@1239|Firmicutes,25B25@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_03948	33035.JPJF01000051_gene766	5.38e-225	621.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3XZ1P@572511|Blautia	186801|Clostridia	EP	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K02031,ko:K02032,ko:K15583	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NFNHFNFO_03949	33035.JPJF01000051_gene765	1.26e-92	279.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24C3R@186801|Clostridia,3XZ61@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	-	-	-	ko:K02032,ko:K10823	ko01501,ko02010,ko02024,map01501,map02010,map02024	M00239,M00439	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5,3.A.1.5.1,3.A.1.5.18,3.A.1.5.19,3.A.1.5.25	-	-	ABC_tran,oligo_HPY
NFNHFNFO_03950	33035.JPJF01000051_gene757	3.72e-170	479.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XYJ3@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NFNHFNFO_03951	33035.JPJF01000051_gene756	3.25e-193	537.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZ8W@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NFNHFNFO_03952	33035.JPJF01000051_gene755	8.88e-196	546.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,247NN@186801|Clostridia,3XZ0U@572511|Blautia	186801|Clostridia	P	Oligopeptide/dipeptide transporter, C-terminal region	-	-	-	ko:K02031	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran,oligo_HPY
NFNHFNFO_03953	33035.JPJF01000051_gene754	3.66e-147	415.0	COG1124@1|root,COG1124@2|Bacteria,1UYAV@1239|Firmicutes,24AEH@186801|Clostridia,3XZ01@572511|Blautia	186801|Clostridia	EP	ATPases associated with a variety of cellular activities	-	-	-	ko:K02032	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	ABC_tran
NFNHFNFO_03954	33035.JPJF01000051_gene753	1.04e-136	387.0	COG0693@1|root,COG0693@2|Bacteria,1V4K4@1239|Firmicutes,24C44@186801|Clostridia,3Y01T@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	DJ-1_PfpI
NFNHFNFO_03955	33035.JPJF01000051_gene752	7.75e-43	141.0	COG1937@1|root,COG1937@2|Bacteria,1UGVX@1239|Firmicutes,25PGS@186801|Clostridia,3Y1WV@572511|Blautia	186801|Clostridia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NFNHFNFO_03956	33035.JPJF01000051_gene751	3.91e-167	468.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia,3XZSI@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
NFNHFNFO_03957	33035.JPJF01000051_gene750	1.06e-279	764.0	COG0334@1|root,COG0334@2|Bacteria,1TQU2@1239|Firmicutes,24AQM@186801|Clostridia	186801|Clostridia	E	Glutamate/Leucine/Phenylalanine/Valine dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
NFNHFNFO_03958	33035.JPJF01000051_gene749	8.37e-265	729.0	COG2271@1|root,COG2271@2|Bacteria,1UZ2K@1239|Firmicutes,2493E@186801|Clostridia,3Y1Q1@572511|Blautia	186801|Clostridia	G	Major Facilitator Superfamily	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NFNHFNFO_03959	33035.JPJF01000051_gene748	9.62e-34	116.0	COG2768@1|root,COG2768@2|Bacteria,1UI12@1239|Firmicutes,25EA0@186801|Clostridia,3Y262@572511|Blautia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
NFNHFNFO_03960	33035.JPJF01000051_gene747	9.65e-249	683.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia,3Y1C2@572511|Blautia	186801|Clostridia	C	Pyruvate:ferredoxin oxidoreductase core domain II	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
NFNHFNFO_03961	33035.JPJF01000051_gene746	9.8e-178	494.0	COG1013@1|root,COG1013@2|Bacteria,1UY5M@1239|Firmicutes,25CAK@186801|Clostridia,3Y2CK@572511|Blautia	186801|Clostridia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
NFNHFNFO_03962	33035.JPJF01000051_gene745	3.14e-121	346.0	COG1014@1|root,COG1014@2|Bacteria,1V39Q@1239|Firmicutes,24G9T@186801|Clostridia,3Y2CI@572511|Blautia	186801|Clostridia	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	POR
NFNHFNFO_03963	33035.JPJF01000051_gene744	0.0	1326.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3Y0Z1@572511|Blautia	186801|Clostridia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
NFNHFNFO_03964	33035.JPJF01000051_gene743	0.0	967.0	COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,2482K@186801|Clostridia,3Y1BM@572511|Blautia	186801|Clostridia	M	BCCT, betaine/carnitine/choline family transporter	-	-	-	ko:K03451	-	-	-	-	ko00000	2.A.15	-	-	BCCT
NFNHFNFO_03965	556261.HMPREF0240_02252	7.64e-208	587.0	COG0477@1|root,COG2814@2|Bacteria,1UHUR@1239|Firmicutes,25E36@186801|Clostridia,36FBN@31979|Clostridiaceae	186801|Clostridia	EGP	Major Facilitator	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
NFNHFNFO_03966	536227.CcarbDRAFT_1642	1.75e-100	298.0	COG1073@1|root,COG1073@2|Bacteria,1U9AI@1239|Firmicutes,24B6Z@186801|Clostridia,36F9A@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
NFNHFNFO_03967	1151292.QEW_4309	6.96e-183	516.0	COG4990@1|root,COG4990@2|Bacteria,1TV6G@1239|Firmicutes,24C6X@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	BtrH_N,DUF4872
NFNHFNFO_03968	1151292.QEW_4308	5.47e-124	360.0	COG0789@1|root,COG4978@1|root,COG0789@2|Bacteria,COG4978@2|Bacteria,1TTBP@1239|Firmicutes,25B7Q@186801|Clostridia	186801|Clostridia	KT	transcriptional regulator, MerR family	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like,MerR_1
NFNHFNFO_03969	1235798.C817_02894	2.87e-18	95.5	COG5263@1|root,COG5263@2|Bacteria	2|Bacteria	S	dextransucrase activity	-	-	-	-	-	-	-	-	-	-	-	-	CW_binding_1,Cadherin-like,Peptidase_S8
NFNHFNFO_03971	33035.JPJF01000051_gene732	1.25e-143	405.0	COG1051@1|root,COG1051@2|Bacteria,1U7WX@1239|Firmicutes,2496B@186801|Clostridia	186801|Clostridia	F	Hydrolase, nudix family	-	-	-	-	-	-	-	-	-	-	-	-	NUDIX,Nudix_N
NFNHFNFO_03972	33035.JPJF01000051_gene731	9.21e-89	261.0	COG0454@1|root,COG0456@2|Bacteria,1V6P2@1239|Firmicutes,24NU3@186801|Clostridia	186801|Clostridia	K	Acetyltransferase, gnat family	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10,Acetyltransf_7
NFNHFNFO_03973	33035.JPJF01000051_gene729	2.48e-118	340.0	COG1670@1|root,COG1670@2|Bacteria,1V6E0@1239|Firmicutes,24G2M@186801|Clostridia,3Y1JZ@572511|Blautia	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	2.3.1.128	ko:K03790	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Acetyltransf_3
NFNHFNFO_03974	97139.C824_05500	2.76e-280	781.0	COG4637@1|root,COG4637@2|Bacteria,1TQ9X@1239|Firmicutes,247NI@186801|Clostridia,36E5J@31979|Clostridiaceae	186801|Clostridia	K	An automated process has identified a potential problem with this gene model	-	-	-	-	-	-	-	-	-	-	-	-	AAA-ATPase_like,PDDEXK_9
NFNHFNFO_03975	33035.JPJF01000051_gene728	3.12e-178	503.0	COG2207@1|root,COG2207@2|Bacteria,1V0EE@1239|Firmicutes,25B24@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NFNHFNFO_03976	33035.JPJF01000051_gene727	6.33e-199	556.0	COG0614@1|root,COG0614@2|Bacteria,1TQMK@1239|Firmicutes,24B1M@186801|Clostridia	186801|Clostridia	P	Periplasmic binding protein	-	-	-	ko:K02016	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	HTH_18,Peripla_BP_2
NFNHFNFO_03977	33035.JPJF01000051_gene726	5.83e-199	556.0	COG0609@1|root,COG0609@2|Bacteria,1TP13@1239|Firmicutes,25CHH@186801|Clostridia	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NFNHFNFO_03978	33035.JPJF01000051_gene725	4.41e-182	513.0	COG0609@1|root,COG0609@2|Bacteria,1TPX6@1239|Firmicutes,24BGM@186801|Clostridia,3Y1D1@572511|Blautia	186801|Clostridia	P	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily	-	-	-	ko:K02015	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.14	-	-	FecCD
NFNHFNFO_03979	33035.JPJF01000051_gene724	4.52e-169	474.0	COG1120@1|root,COG1120@2|Bacteria,1TP2Q@1239|Firmicutes,2492Z@186801|Clostridia,3XZZ8@572511|Blautia	186801|Clostridia	HP	ATPases associated with a variety of cellular activities	fhuC	-	3.6.3.34	ko:K02013	ko02010,map02010	M00240	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.14	-	-	ABC_tran
NFNHFNFO_03980	33035.JPJF01000051_gene723	0.0	879.0	COG0437@1|root,COG4624@1|root,COG0437@2|Bacteria,COG4624@2|Bacteria,1TQIR@1239|Firmicutes,248BS@186801|Clostridia,3XYSR@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fe_hyd_lg_C,Fer4,Fer4_6
NFNHFNFO_03981	33035.JPJF01000014_gene4811	1.53e-16	73.2	2DJ8W@1|root,30516@2|Bacteria,1TUX7@1239|Firmicutes,25I10@186801|Clostridia,3Y21N@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_03982	1232447.BAHW02000040_gene2766	8.1e-68	207.0	2C5R4@1|root,2ZC1N@2|Bacteria,1V292@1239|Firmicutes,25CQM@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	TnpV
NFNHFNFO_03983	658086.HMPREF0994_02252	4.35e-123	352.0	COG1309@1|root,COG1309@2|Bacteria,1V0XA@1239|Firmicutes,24M3A@186801|Clostridia,27KGU@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_03984	658086.HMPREF0994_02253	1.69e-76	229.0	2E49F@1|root,32Z57@2|Bacteria,1VA75@1239|Firmicutes,24NSI@186801|Clostridia,27QGE@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4180)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4180
NFNHFNFO_03985	1262914.BN533_02170	4.49e-10	58.2	COG0454@1|root,COG0456@2|Bacteria,1VAAI@1239|Firmicutes,4H5RB@909932|Negativicutes	909932|Negativicutes	K	Acetyltransferase (GNAT) domain	-	-	-	ko:K03827	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10
NFNHFNFO_03986	33035.JPJF01000053_gene1570	2.97e-135	385.0	2C5Z2@1|root,32TBG@2|Bacteria,1V65A@1239|Firmicutes,25DSJ@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF3786)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3786
NFNHFNFO_03988	742733.HMPREF9469_03997	2.36e-200	560.0	COG3541@1|root,COG3541@2|Bacteria,1UZ8D@1239|Firmicutes,24AZG@186801|Clostridia,21YF5@1506553|Lachnoclostridium	186801|Clostridia	S	Predicted nucleotidyltransferase	-	-	-	ko:K07074	-	-	-	-	ko00000	-	-	-	Nuc-transf
NFNHFNFO_03989	33035.JPJF01000053_gene1572	6.51e-119	344.0	COG1418@1|root,COG1418@2|Bacteria,1V2RJ@1239|Firmicutes,25B26@186801|Clostridia	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K06950	-	-	-	-	ko00000	-	-	-	HD
NFNHFNFO_03990	33035.JPJF01000053_gene1574	8.98e-198	549.0	COG1533@1|root,COG1533@2|Bacteria,1TSS2@1239|Firmicutes,248SB@186801|Clostridia	186801|Clostridia	L	Radical SAM domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NFNHFNFO_03991	33035.JPJF01000053_gene1575	9.81e-125	357.0	COG2020@1|root,COG2020@2|Bacteria,1V3IZ@1239|Firmicutes,24FW3@186801|Clostridia	186801|Clostridia	O	Isoprenylcysteine carboxyl methyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	DUF218,PEMT
NFNHFNFO_03992	33035.JPJF01000053_gene1576	5.61e-159	452.0	COG0454@1|root,COG1670@1|root,COG0456@2|Bacteria,COG1670@2|Bacteria,1VAFS@1239|Firmicutes,24MUI@186801|Clostridia,3Y0CK@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03826	-	-	-	-	ko00000,ko01000	-	-	-	Acetyltransf_10,Acetyltransf_7
NFNHFNFO_03993	33035.JPJF01000053_gene1577	3.95e-74	224.0	COG0494@1|root,COG0494@2|Bacteria,1UHVA@1239|Firmicutes,24PC0@186801|Clostridia	186801|Clostridia	L	Psort location Cytoplasmic, score	-	-	3.6.1.55	ko:K03574	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	NUDIX
NFNHFNFO_03994	33035.JPJF01000053_gene1578	1.44e-156	439.0	COG2013@1|root,COG2013@2|Bacteria,1TPN2@1239|Firmicutes,2499B@186801|Clostridia,3Y0AC@572511|Blautia	186801|Clostridia	S	cog cog2013	-	-	-	-	-	-	-	-	-	-	-	-	AIM24
NFNHFNFO_03995	33035.JPJF01000053_gene1579	5.45e-234	645.0	COG3012@1|root,COG3012@2|Bacteria,1UK0V@1239|Firmicutes,24DYG@186801|Clostridia	186801|Clostridia	S	SEC-C Motif Domain Protein	-	-	-	-	-	-	-	-	-	-	-	-	PRiA4_ORF3
NFNHFNFO_03996	33035.JPJF01000053_gene1580	6.61e-256	702.0	COG1609@1|root,COG1609@2|Bacteria,1TP9Q@1239|Firmicutes,24ARJ@186801|Clostridia,3Y051@572511|Blautia	186801|Clostridia	K	Periplasmic binding protein-like domain	araR	-	-	ko:K02103	-	-	-	-	ko00000,ko03000	-	-	-	GntR,Peripla_BP_3
NFNHFNFO_03997	33035.JPJF01000053_gene1581	0.0	1040.0	COG1069@1|root,COG1069@2|Bacteria,1UHVR@1239|Firmicutes,25E4P@186801|Clostridia	186801|Clostridia	C	Belongs to the FGGY kinase family	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_03998	33035.JPJF01000053_gene1582	1.91e-167	467.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,3XYMH@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	araD	-	5.1.3.4	ko:K03077	ko00040,ko00053,ko01100,ko01120,map00040,map00053,map01100,map01120	M00550	R05850	RC01479	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldolase_II
NFNHFNFO_03999	33035.JPJF01000053_gene1583	0.0	1003.0	COG1070@1|root,COG1070@2|Bacteria,1TP91@1239|Firmicutes,24A4Z@186801|Clostridia,3XYGM@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	araB	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_04000	33035.JPJF01000053_gene1584	3.8e-95	278.0	COG4194@1|root,COG4194@2|Bacteria,1V3Z3@1239|Firmicutes,24KZ8@186801|Clostridia,3Y1WD@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1648)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1648
NFNHFNFO_04001	33035.JPJF01000053_gene1585	1.69e-183	511.0	COG1234@1|root,COG1234@2|Bacteria,1TPSW@1239|Firmicutes,249RR@186801|Clostridia,3XYRY@572511|Blautia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	3.1.26.11	ko:K00784	ko03013,map03013	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	Lactamase_B_2
NFNHFNFO_04002	33035.JPJF01000053_gene1586	1.68e-60	186.0	2DMMF@1|root,32SEK@2|Bacteria,1VAB3@1239|Firmicutes,24N8S@186801|Clostridia,3Y0F2@572511|Blautia	186801|Clostridia	S	COG NOG21970 non supervised orthologous group	-	-	-	-	-	-	-	-	-	-	-	-	DUF2325
NFNHFNFO_04003	33035.JPJF01000053_gene1587	7.59e-115	330.0	2BYWB@1|root,32SGE@2|Bacteria,1VAZ2@1239|Firmicutes,24J86@186801|Clostridia,3Y04A@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3793
NFNHFNFO_04004	33035.JPJF01000053_gene1588	9.42e-83	246.0	COG0716@1|root,COG0716@2|Bacteria,1V6D7@1239|Firmicutes,24J7W@186801|Clostridia,3Y024@572511|Blautia	186801|Clostridia	C	Flavodoxin domain	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_1
NFNHFNFO_04005	33035.JPJF01000053_gene1589	1.31e-168	473.0	COG0428@1|root,COG0428@2|Bacteria,1TP7J@1239|Firmicutes,247Q2@186801|Clostridia,3XYRK@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 9.99	zupT	-	-	ko:K07238	-	-	-	-	ko00000,ko02000	2.A.5.5	-	-	Zip
NFNHFNFO_04006	33035.JPJF01000053_gene1590	2.13e-232	641.0	COG3250@1|root,COG3250@2|Bacteria,1TSMY@1239|Firmicutes,24B54@186801|Clostridia	186801|Clostridia	G	Protein of unknown function (DUF2804)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2804
NFNHFNFO_04007	33035.JPJF01000053_gene1591	2.12e-50	160.0	COG1937@1|root,COG1937@2|Bacteria,1USSN@1239|Firmicutes,25AU5@186801|Clostridia,3Y0HY@572511|Blautia	186801|Clostridia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NFNHFNFO_04008	33035.JPJF01000053_gene1592	0.0	1476.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3XZ6B@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	actP	-	3.6.3.4,3.6.3.54	ko:K01533,ko:K17686	ko01524,ko04016,map01524,map04016	-	R00086	RC00002	ko00000,ko00001,ko01000	3.A.3.5	-	-	E1-E2_ATPase,HMA,Hydrolase
NFNHFNFO_04009	33035.JPJF01000053_gene1593	3.66e-115	331.0	COG0245@1|root,COG0245@2|Bacteria,1V3P0@1239|Firmicutes,24HCM@186801|Clostridia,3XZW5@572511|Blautia	186801|Clostridia	H	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP)	ispF	-	2.7.7.60,4.6.1.12	ko:K01770,ko:K12506	ko00900,ko01100,ko01110,ko01130,map00900,map01100,map01110,map01130	M00096	R05633,R05637	RC00002,RC01440	ko00000,ko00001,ko00002,ko01000	-	-	-	IspD,YgbB
NFNHFNFO_04010	33035.JPJF01000053_gene1594	0.0	1003.0	COG0488@1|root,COG0488@2|Bacteria,1TPAX@1239|Firmicutes,247U6@186801|Clostridia,3XYSE@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	yfmM	-	-	ko:K06158	-	-	-	-	ko00000,ko03012	-	-	-	ABC_tran,ABC_tran_Xtn
NFNHFNFO_04011	33035.JPJF01000053_gene1595	6.37e-313	853.0	COG0334@1|root,COG0334@2|Bacteria,1TP45@1239|Firmicutes,24960@186801|Clostridia,3XZ9J@572511|Blautia	186801|Clostridia	C	Belongs to the Glu Leu Phe Val dehydrogenases family	gdhA	-	1.4.1.3,1.4.1.4	ko:K00261,ko:K00262	ko00220,ko00250,ko00471,ko00910,ko01100,ko01200,ko04217,ko04964,map00220,map00250,map00471,map00910,map01100,map01200,map04217,map04964	M00740	R00243,R00248	RC00006,RC02799	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	ELFV_dehydrog,ELFV_dehydrog_N
NFNHFNFO_04012	556268.OFAG_01023	3.81e-161	512.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1NRP8@1224|Proteobacteria,2VGZQ@28216|Betaproteobacteria	28216|Betaproteobacteria	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	CHASE,HATPase_c,HisKA,Hpt,PAS,PAS_3,PAS_4,PAS_9,Response_reg,dCache_1
NFNHFNFO_04013	33035.JPJF01000053_gene1596	0.0	1305.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3XZE8@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,Response_reg
NFNHFNFO_04015	1378168.N510_01972	3e-66	226.0	COG2199@1|root,COG2199@2|Bacteria,1V8BN@1239|Firmicutes	1239|Firmicutes	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3,dCache_1
NFNHFNFO_04017	33035.JPJF01000053_gene1598	1.38e-148	419.0	COG1045@1|root,COG1045@2|Bacteria,1TR42@1239|Firmicutes,249SF@186801|Clostridia,3XYRQ@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score	cysE	-	2.3.1.30	ko:K00640	ko00270,ko00920,ko01100,ko01110,ko01120,ko01200,ko01230,ko05111,map00270,map00920,map01100,map01110,map01120,map01200,map01230,map05111	M00021	R00586	RC00004,RC00041	ko00000,ko00001,ko00002,ko01000	-	-	-	Hexapep,SATase_N
NFNHFNFO_04018	33035.JPJF01000053_gene1599	0.0	905.0	COG0215@1|root,COG0215@2|Bacteria,1TP9D@1239|Firmicutes,247KS@186801|Clostridia,3XZA4@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	cysS	-	6.1.1.16	ko:K01883	ko00970,map00970	M00359,M00360	R03650	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	DALR_2,tRNA-synt_1e,tRNA-synt_1g
NFNHFNFO_04019	33035.JPJF01000053_gene1600	6.19e-93	272.0	COG1939@1|root,COG1939@2|Bacteria,1VA5V@1239|Firmicutes,24MR1@186801|Clostridia,3Y00G@572511|Blautia	186801|Clostridia	J	Involved in correct processing of both the 5' and 3' ends of 23S rRNA precursor. Processes 30S rRNA precursor transcript even in absence of ribonuclease 3 (Rnc)	mrnC	-	-	ko:K11145	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Ribonuclease_3
NFNHFNFO_04020	33035.JPJF01000053_gene1601	1.61e-169	474.0	COG0566@1|root,COG0566@2|Bacteria,1TP9G@1239|Firmicutes,247SC@186801|Clostridia,3XZ93@572511|Blautia	186801|Clostridia	J	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family	yacO	-	2.1.1.185	ko:K03218	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	SpoU_methylase,SpoU_sub_bind
NFNHFNFO_04021	33035.JPJF01000053_gene1602	6.17e-124	354.0	COG1595@1|root,COG1595@2|Bacteria,1TP55@1239|Firmicutes,249VX@186801|Clostridia,3XZYB@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	sigH	-	-	ko:K03091	-	-	-	-	ko00000,ko03021	-	-	-	GerE,Sigma70_r2,Sigma70_r4_2
NFNHFNFO_04022	33035.JPJF01000053_gene1603	8.5e-287	786.0	COG1253@1|root,COG1253@2|Bacteria,1TPN0@1239|Firmicutes,2489N@186801|Clostridia,3XYYB@572511|Blautia	186801|Clostridia	S	COG COG1253 Hemolysins and related proteins containing CBS domains	-	-	-	ko:K03699	-	-	-	-	ko00000,ko02042	-	-	-	CBS,CorC_HlyC,DUF21
NFNHFNFO_04023	33035.JPJF01000053_gene1604	1.76e-231	637.0	COG0111@1|root,COG0111@2|Bacteria,1TSDK@1239|Firmicutes,247Q4@186801|Clostridia	186801|Clostridia	EH	D-isomer specific 2-hydroxyacid dehydrogenase	-	-	1.1.1.79,1.1.1.81	ko:K12972	ko00260,ko00620,ko00630,ko01100,ko01110,ko01120,map00260,map00620,map00630,map01100,map01110,map01120	-	R00465,R01388,R01392,R02527	RC00031,RC00042,RC00670	ko00000,ko00001,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NFNHFNFO_04025	33035.JPJF01000053_gene1605	4.88e-128	364.0	COG3822@1|root,COG3822@2|Bacteria,1V1ZU@1239|Firmicutes,24ENY@186801|Clostridia	186801|Clostridia	S	ABC-type sugar transport system, auxiliary component	-	-	5.3.1.15	ko:K09988	ko00040,map00040	-	R01898	RC00516	ko00000,ko00001,ko01000	-	-	-	Lyx_isomer
NFNHFNFO_04026	33035.JPJF01000053_gene1606	0.0	1464.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,248B9@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFNHFNFO_04027	33035.JPJF01000053_gene1607	3.7e-314	858.0	COG1653@1|root,COG1653@2|Bacteria,1TSHR@1239|Firmicutes,24D6W@186801|Clostridia	1239|Firmicutes	G	Extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_04028	33035.JPJF01000053_gene1608	2.23e-205	569.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04029	33035.JPJF01000053_gene1609	1.05e-176	494.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3Y2B5@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_04030	33035.JPJF01000053_gene1610	1.47e-192	537.0	COG2390@1|root,COG2390@2|Bacteria,1TPUB@1239|Firmicutes,25D2S@186801|Clostridia,3Y1VG@572511|Blautia	186801|Clostridia	K	Putative sugar-binding domain	deoR	-	-	ko:K05346	-	-	-	-	ko00000,ko03000	-	-	-	HTH_23,HTH_24,Sigma70_r4,Sugar-bind
NFNHFNFO_04031	33035.JPJF01000053_gene1611	6.47e-225	622.0	COG1063@1|root,COG1063@2|Bacteria,1U9ZD@1239|Firmicutes,24EJR@186801|Clostridia,3Y2BF@572511|Blautia	186801|Clostridia	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_04032	33035.JPJF01000053_gene1612	2.38e-246	677.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,3XZWH@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_04033	33035.JPJF01000053_gene1613	3.14e-130	372.0	COG0274@1|root,COG0274@2|Bacteria,1TPAJ@1239|Firmicutes,249XB@186801|Clostridia,3XZXA@572511|Blautia	186801|Clostridia	F	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate	deoC	-	4.1.2.4	ko:K01619	ko00030,map00030	-	R01066	RC00436,RC00437	ko00000,ko00001,ko01000	-	-	-	DeoC
NFNHFNFO_04034	33035.JPJF01000053_gene1614	0.0	917.0	COG1070@1|root,COG1070@2|Bacteria,1VS1J@1239|Firmicutes,24YN2@186801|Clostridia	186801|Clostridia	G	FGGY family of carbohydrate kinases, N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_04035	33035.JPJF01000053_gene1615	5.04e-26	109.0	COG3250@1|root,COG3250@2|Bacteria,1UZDI@1239|Firmicutes,24C7N@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_N
NFNHFNFO_04036	33035.JPJF01000053_gene1615	0.0	1301.0	COG3250@1|root,COG3250@2|Bacteria,1UZDI@1239|Firmicutes,24C7N@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_2,Glyco_hydro_2_N
NFNHFNFO_04037	33035.JPJF01000053_gene1616	0.0	1391.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia	186801|Clostridia	G	beta-galactosidase	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42M
NFNHFNFO_04038	33035.JPJF01000063_gene3677	2.08e-214	593.0	COG0549@1|root,COG0549@2|Bacteria,1TP9H@1239|Firmicutes,2482W@186801|Clostridia,3XZFB@572511|Blautia	186801|Clostridia	E	Amino acid kinase family	arcC	-	2.7.2.2	ko:K00926	ko00220,ko00230,ko00910,ko01100,ko01120,ko01200,map00220,map00230,map00910,map01100,map01120,map01200	-	R00150,R01395	RC00002,RC00043,RC02803,RC02804	ko00000,ko00001,ko01000	-	-	-	AA_kinase
NFNHFNFO_04039	33035.JPJF01000063_gene3678	3.92e-290	791.0	COG0078@1|root,COG0078@2|Bacteria,1TNY4@1239|Firmicutes,249P4@186801|Clostridia,3XYQV@572511|Blautia	186801|Clostridia	E	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain	ygeW	-	-	-	-	-	-	-	-	-	-	-	OTCace,OTCace_N
NFNHFNFO_04040	33035.JPJF01000063_gene3679	6.77e-313	851.0	COG0624@1|root,COG0624@2|Bacteria,1TR99@1239|Firmicutes,248DC@186801|Clostridia,3XYM0@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
NFNHFNFO_04041	33035.JPJF01000063_gene3680	3.65e-293	800.0	COG1171@1|root,COG1171@2|Bacteria,1TR70@1239|Firmicutes,2485T@186801|Clostridia,3XZ80@572511|Blautia	186801|Clostridia	E	Pyridoxal-phosphate dependent enzyme	dpaL	-	4.3.1.15	ko:K01751	-	-	-	-	ko00000,ko01000	-	-	-	PALP
NFNHFNFO_04042	33035.JPJF01000063_gene3681	3.82e-148	417.0	COG2964@1|root,COG2964@2|Bacteria,1TSI2@1239|Firmicutes,249X6@186801|Clostridia,3XZQ3@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	HTH_22,PAS_6
NFNHFNFO_04043	33035.JPJF01000063_gene3682	1.56e-46	149.0	2DNWW@1|root,32ZKQ@2|Bacteria,1VEZD@1239|Firmicutes,24REP@186801|Clostridia,3Y2CR@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF3343)	-	-	-	-	-	-	-	-	-	-	-	-	DUF3343
NFNHFNFO_04044	33035.JPJF01000063_gene3683	0.0	1649.0	COG1529@1|root,COG2080@1|root,COG1529@2|Bacteria,COG2080@2|Bacteria,1TP7U@1239|Firmicutes,248BV@186801|Clostridia,3XYY3@572511|Blautia	186801|Clostridia	C	COG COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs	-	-	-	-	-	-	-	-	-	-	-	-	Ald_Xan_dh_C,Ald_Xan_dh_C2,Fer2,Fer2_2
NFNHFNFO_04045	33035.JPJF01000063_gene3684	1.55e-307	841.0	COG0044@1|root,COG0044@2|Bacteria,1TP8C@1239|Firmicutes,249W6@186801|Clostridia,3XZ6S@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	hydA	-	3.5.2.2	ko:K01464	ko00240,ko00410,ko00770,ko00983,ko01100,map00240,map00410,map00770,map00983,map01100	M00046	R02269,R03055,R08227	RC00632,RC00680	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Amidohydro_1
NFNHFNFO_04046	33035.JPJF01000063_gene3685	1.79e-121	349.0	COG0425@1|root,COG0425@2|Bacteria,1V6BY@1239|Firmicutes,24JW8@186801|Clostridia,3Y06N@572511|Blautia	186801|Clostridia	O	COG NOG13230 non supervised orthologous group	yedF	-	-	ko:K04085	ko04122,map04122	-	-	-	ko00000,ko00001,ko01000,ko03016	-	-	-	DrsE,TusA
NFNHFNFO_04047	33035.JPJF01000063_gene3686	3.69e-170	478.0	COG3608@1|root,COG3608@2|Bacteria,1TRKT@1239|Firmicutes,2492W@186801|Clostridia,3XZWY@572511|Blautia	186801|Clostridia	S	COG COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family	-	-	-	ko:K07402	-	-	-	-	ko00000	-	-	-	NTP_transf_3
NFNHFNFO_04048	33035.JPJF01000063_gene3687	5.65e-267	738.0	COG2068@1|root,COG2068@2|Bacteria,1VA0F@1239|Firmicutes,24NSX@186801|Clostridia,3Y0EX@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	2.7.7.76	ko:K07141	ko00790,map00790	-	R11582	-	ko00000,ko00001,ko01000	-	-	-	NTP_transf_3
NFNHFNFO_04049	33035.JPJF01000063_gene3688	5.92e-54	170.0	COG1396@1|root,COG1396@2|Bacteria,1VIXK@1239|Firmicutes,24T9B@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_04050	33035.JPJF01000063_gene3689	5.13e-192	535.0	COG5001@1|root,COG5001@2|Bacteria	2|Bacteria	T	cyclic-guanylate-specific phosphodiesterase activity	-	-	2.1.1.80,3.1.1.61	ko:K13924	ko02020,ko02030,map02020,map02030	M00506	-	-	ko00000,ko00001,ko00002,ko01000,ko02022,ko02035	-	-	-	CHASE4,CheB_methylest,CheR,CheR_N,EAL,GGDEF,PAS_3,PAS_9,SBP_bac_3
NFNHFNFO_04051	33035.JPJF01000063_gene3690	7.7e-110	316.0	COG1854@1|root,COG1854@2|Bacteria,1V1CH@1239|Firmicutes,24G3R@186801|Clostridia,3XZVQ@572511|Blautia	186801|Clostridia	H	Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD)	luxS	-	4.4.1.21	ko:K07173	ko00270,ko01100,ko01230,ko02024,ko02026,ko05111,map00270,map01100,map01230,map02024,map02026,map05111	M00609	R01291	RC00069,RC01929	ko00000,ko00001,ko00002,ko01000	-	-	-	LuxS
NFNHFNFO_04052	33035.JPJF01000063_gene3691	4.13e-270	745.0	COG5002@1|root,COG5002@2|Bacteria,1URKI@1239|Firmicutes,248WK@186801|Clostridia,3XZE3@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_04053	33035.JPJF01000063_gene3692	1.27e-150	424.0	COG0745@1|root,COG0745@2|Bacteria,1UZIS@1239|Firmicutes,24CCE@186801|Clostridia,3XYX9@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_04054	33035.JPJF01000063_gene3693	0.0	1184.0	COG1653@1|root,COG1653@2|Bacteria,1V04I@1239|Firmicutes,247SU@186801|Clostridia,3XZJE@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_04055	33035.JPJF01000063_gene3694	9.87e-184	513.0	COG1175@1|root,COG1175@2|Bacteria,1TQTC@1239|Firmicutes,24AQX@186801|Clostridia,3Y0K9@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_04056	33035.JPJF01000063_gene3695	2.01e-182	509.0	COG0395@1|root,COG0395@2|Bacteria,1TS82@1239|Firmicutes,2488S@186801|Clostridia,3XYW1@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04057	33035.JPJF01000063_gene3696	5.54e-217	619.0	COG0845@1|root,COG0845@2|Bacteria,1V156@1239|Firmicutes,24E26@186801|Clostridia,3Y06F@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Biotin_lipoyl_2,HlyD_3,HlyD_D23
NFNHFNFO_04058	33035.JPJF01000063_gene3697	2.02e-180	514.0	2BF19@1|root,328T3@2|Bacteria,1VAXF@1239|Firmicutes,258NW@186801|Clostridia,3Y0UJ@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04059	33035.JPJF01000063_gene3700	4.53e-239	657.0	COG0180@1|root,COG0180@2|Bacteria,1TPY7@1239|Firmicutes,248RC@186801|Clostridia,3XZHE@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	trpS	-	6.1.1.2	ko:K01867	ko00970,map00970	M00359,M00360	R03664	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	tRNA-synt_1b
NFNHFNFO_04060	33035.JPJF01000063_gene3701	1.52e-112	323.0	COG4702@1|root,COG4702@2|Bacteria,1V6Q9@1239|Firmicutes,24KK6@186801|Clostridia,3Y0ZS@572511|Blautia	186801|Clostridia	S	Haem-degrading	-	-	-	-	-	-	-	-	-	-	-	-	Haem_degrading
NFNHFNFO_04061	33035.JPJF01000063_gene3702	2.9e-68	207.0	arCOG03368@1|root,331XD@2|Bacteria,1VHY0@1239|Firmicutes,24SSZ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04062	33035.JPJF01000063_gene3703	1.23e-173	489.0	COG0564@1|root,COG0564@2|Bacteria,1TS1T@1239|Firmicutes,249AH@186801|Clostridia,3XYU7@572511|Blautia	186801|Clostridia	J	Responsible for synthesis of pseudouridine from uracil	rluD_2	-	5.4.99.23	ko:K06180	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	PseudoU_synth_2
NFNHFNFO_04063	33035.JPJF01000063_gene3704	0.0	1167.0	COG0687@1|root,COG1177@1|root,COG0687@2|Bacteria,COG1177@2|Bacteria,1TPY1@1239|Firmicutes,2483K@186801|Clostridia,3XZ62@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	potD	-	-	ko:K11069	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1,SBP_bac_6,SBP_bac_8
NFNHFNFO_04064	33035.JPJF01000063_gene3705	4.58e-180	503.0	COG1176@1|root,COG1176@2|Bacteria,1TQ7Z@1239|Firmicutes,247Y8@186801|Clostridia,3XYI0@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	potB	-	-	ko:K11071	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.11.1	-	-	BPD_transp_1
NFNHFNFO_04065	33035.JPJF01000063_gene3706	1.06e-260	714.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,247JR@186801|Clostridia,3XZIF@572511|Blautia	186801|Clostridia	P	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system	potA	-	3.6.3.31	ko:K11072	ko02010,map02010	M00299	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.11.1	-	-	ABC_tran,TOBE_2
NFNHFNFO_04066	33035.JPJF01000063_gene3707	1.69e-259	710.0	COG2706@1|root,COG2706@2|Bacteria,1TQ3J@1239|Firmicutes,248JF@186801|Clostridia,3XZ28@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	3.1.1.31	ko:K07404	ko00030,ko01100,ko01110,ko01120,ko01130,ko01200,map00030,map01100,map01110,map01120,map01130,map01200	M00004,M00006,M00008	R02035	RC00537	ko00000,ko00001,ko00002,ko01000	-	-	-	Lactonase
NFNHFNFO_04067	33035.JPJF01000063_gene3708	1.83e-207	575.0	COG0598@1|root,COG0598@2|Bacteria,1TPI8@1239|Firmicutes,24956@186801|Clostridia,3XZ0H@572511|Blautia	186801|Clostridia	P	CorA-like Mg2+ transporter protein	corA	-	-	ko:K03284	-	-	-	-	ko00000,ko02000	1.A.35.1,1.A.35.3	-	-	CorA
NFNHFNFO_04068	33035.JPJF01000063_gene3709	3.06e-193	536.0	COG0705@1|root,COG0705@2|Bacteria,1TSBP@1239|Firmicutes,249D8@186801|Clostridia,3XYV8@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Rhomboid
NFNHFNFO_04069	33035.JPJF01000063_gene3710	0.0	920.0	COG0469@1|root,COG0469@2|Bacteria,1TPGG@1239|Firmicutes,2489V@186801|Clostridia,3XZ4X@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pyk	-	2.7.1.40	ko:K00873	ko00010,ko00230,ko00620,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,ko04922,ko04930,ko05165,ko05203,ko05230,map00010,map00230,map00620,map01100,map01110,map01120,map01130,map01200,map01230,map04922,map04930,map05165,map05203,map05230	M00001,M00002,M00049,M00050	R00200,R00430,R01138,R01858,R02320	RC00002,RC00015	ko00000,ko00001,ko00002,ko01000,ko04131,ko04147	-	-	-	PEP-utilizers,PK,PK_C
NFNHFNFO_04070	33035.JPJF01000063_gene3711	1.26e-146	415.0	COG0637@1|root,COG0637@2|Bacteria,1VA5Z@1239|Firmicutes,24JNY@186801|Clostridia,3Y042@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	HAD_2,Mannitol_dh_C
NFNHFNFO_04071	33035.JPJF01000063_gene3712	1.16e-302	825.0	COG0019@1|root,COG0019@2|Bacteria,1TPE9@1239|Firmicutes,247X7@186801|Clostridia,3XZ9R@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	lysA	-	4.1.1.20	ko:K01586	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00526,M00527	R00451	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	Orn_Arg_deC_N,Orn_DAP_Arg_deC
NFNHFNFO_04072	33035.JPJF01000063_gene3713	1.2e-261	718.0	COG0641@1|root,COG0641@2|Bacteria,1TQPS@1239|Firmicutes,247Z9@186801|Clostridia,3XZWW@572511|Blautia	186801|Clostridia	C	Iron-sulfur cluster-binding domain	-	-	-	ko:K06871	-	-	-	-	ko00000	-	-	-	Fer4_12,Radical_SAM,SEC-C,SPASM
NFNHFNFO_04073	33035.JPJF01000063_gene3714	0.0	1050.0	COG2972@1|root,COG2972@2|Bacteria,1UUVF@1239|Firmicutes,25KD6@186801|Clostridia,3Y1M2@572511|Blautia	186801|Clostridia	T	Histidine kinase	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase
NFNHFNFO_04074	33035.JPJF01000063_gene3715	3.22e-315	866.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TT52@1239|Firmicutes,249A9@186801|Clostridia	186801|Clostridia	T	COG COG4753 Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_04075	33035.JPJF01000063_gene3716	1.73e-304	832.0	COG1653@1|root,COG1653@2|Bacteria,1U4H4@1239|Firmicutes,25EA6@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1
NFNHFNFO_04076	33035.JPJF01000063_gene3717	5.11e-189	527.0	COG1175@1|root,COG1175@2|Bacteria,1TR22@1239|Firmicutes,25C4S@186801|Clostridia,3Y1N2@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04077	33035.JPJF01000063_gene3718	7.92e-189	526.0	COG0395@1|root,COG0395@2|Bacteria,1V0I1@1239|Firmicutes,24DHU@186801|Clostridia	186801|Clostridia	P	sugar transport system permease	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_04078	33035.JPJF01000063_gene3719	0.0	916.0	COG3119@1|root,COG3119@2|Bacteria,1TQEP@1239|Firmicutes,2482B@186801|Clostridia,3Y0RM@572511|Blautia	186801|Clostridia	P	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF4976,Sulfatase
NFNHFNFO_04079	33035.JPJF01000063_gene3720	0.0	1350.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3Y15E@572511|Blautia	186801|Clostridia	G	Beta-galactosidase	-	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NFNHFNFO_04080	33035.JPJF01000063_gene3721	3.27e-182	516.0	COG1277@1|root,COG1277@2|Bacteria,1VWKS@1239|Firmicutes,25M9V@186801|Clostridia,3Y21D@572511|Blautia	186801|Clostridia	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04081	33035.JPJF01000063_gene3722	6.08e-179	501.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3XZE4@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_04082	33035.JPJF01000063_gene3723	3.19e-126	365.0	2FFUY@1|root,347S0@2|Bacteria,1VYP7@1239|Firmicutes,253QZ@186801|Clostridia,3Y23M@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04083	33035.JPJF01000063_gene3724	4.12e-101	296.0	COG1595@1|root,COG1595@2|Bacteria,1V84D@1239|Firmicutes,25B29@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_04084	553973.CLOHYLEM_04051	3.13e-122	355.0	COG0716@1|root,COG1149@1|root,COG0716@2|Bacteria,COG1149@2|Bacteria,1V767@1239|Firmicutes,24C3D@186801|Clostridia,21Z19@1506553|Lachnoclostridium	186801|Clostridia	C	binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_4,Fer4_9,Flavodoxin_5
NFNHFNFO_04085	1123075.AUDP01000043_gene2025	3.28e-62	192.0	COG0640@1|root,COG0640@2|Bacteria,1V6Z2@1239|Firmicutes,24JUM@186801|Clostridia,3WQR3@541000|Ruminococcaceae	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
NFNHFNFO_04086	411490.ANACAC_01083	1.14e-120	351.0	COG0778@1|root,COG2221@1|root,COG0778@2|Bacteria,COG2221@2|Bacteria,1TPKH@1239|Firmicutes,249WN@186801|Clostridia	186801|Clostridia	C	PFAM Nitroreductase	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_10,Fer4_4,Fer4_7,Fer4_9,Nitroreductase
NFNHFNFO_04087	33035.JPJF01000063_gene3727	1.55e-42	139.0	28U5H@1|root,2ZGBC@2|Bacteria,1W496@1239|Firmicutes,2557X@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04090	411461.DORFOR_01898	4.53e-109	319.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,27WNW@189330|Dorea	186801|Clostridia	K	Transcriptional regulatory protein, C terminal	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_04091	33035.JPJF01000063_gene3733	3.43e-229	637.0	COG0642@1|root,COG3850@1|root,COG2205@2|Bacteria,COG3850@2|Bacteria,1TRZX@1239|Firmicutes,249AI@186801|Clostridia,3XYP2@572511|Blautia	186801|Clostridia	T	HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,HisKA
NFNHFNFO_04092	33035.JPJF01000063_gene3734	2.85e-266	729.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia,3Y021@572511|Blautia	186801|Clostridia	C	Aldo/keto reductase family	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17,Fer4_9
NFNHFNFO_04093	33035.JPJF01000063_gene3736	2.71e-210	586.0	COG1277@1|root,COG1277@2|Bacteria,1UYRU@1239|Firmicutes,24A07@186801|Clostridia,3XZKS@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC2_membrane_2
NFNHFNFO_04094	33035.JPJF01000063_gene3737	1.26e-109	322.0	2B7SS@1|root,320Z4@2|Bacteria,1V805@1239|Firmicutes	1239|Firmicutes	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04095	33035.JPJF01000063_gene3738	1.87e-172	485.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3XZ40@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_04096	33035.JPJF01000063_gene3739	2.26e-274	758.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3XYWG@572511|Blautia	186801|Clostridia	O	COG COG0265 Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain	degQ	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
NFNHFNFO_04097	33035.JPJF01000063_gene3740	1.16e-112	327.0	COG2844@1|root,COG2844@2|Bacteria,1V2GH@1239|Firmicutes,24FRR@186801|Clostridia	186801|Clostridia	O	HD domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
NFNHFNFO_04098	33035.JPJF01000063_gene3741	8.51e-91	267.0	COG0454@1|root,COG0456@2|Bacteria,1V433@1239|Firmicutes,24HYV@186801|Clostridia,3Y0TX@572511|Blautia	186801|Clostridia	K	FR47-like protein	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
NFNHFNFO_04099	33035.JPJF01000063_gene3742	4.87e-108	314.0	COG0454@1|root,COG0456@2|Bacteria,1V2CK@1239|Firmicutes,24KFX@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_04100	556261.HMPREF0240_02933	6.49e-244	679.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,36DT9@31979|Clostridiaceae	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_04101	553973.CLOHYLEM_04485	3.07e-42	144.0	2F94V@1|root,341GD@2|Bacteria,1VYDU@1239|Firmicutes,24SFR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04102	33035.JPJF01000097_gene1712	1.59e-172	485.0	28JN4@1|root,2Z9EJ@2|Bacteria,1TRQI@1239|Firmicutes,24E4X@186801|Clostridia,3Y281@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_31
NFNHFNFO_04103	33035.JPJF01000041_gene293	9.41e-259	714.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1UUV7@1239|Firmicutes,25KCZ@186801|Clostridia,3Y1SF@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,Response_reg
NFNHFNFO_04104	33035.JPJF01000041_gene294	0.0	954.0	COG2972@1|root,COG2972@2|Bacteria,1UZQN@1239|Firmicutes,24E85@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	His_kinase
NFNHFNFO_04105	33035.JPJF01000041_gene295	2.91e-303	829.0	COG1653@1|root,COG1653@2|Bacteria,1V14H@1239|Firmicutes,25B1V@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04106	33035.JPJF01000041_gene296	2.37e-191	533.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_04107	33035.JPJF01000041_gene297	6.96e-178	498.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_04108	33035.JPJF01000041_gene298	0.0	1074.0	COG0366@1|root,COG0366@2|Bacteria	2|Bacteria	G	hydrolase activity, hydrolyzing O-glycosyl compounds	glgE	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,GDE_C,GDE_N,hDGE_amylase
NFNHFNFO_04109	33035.JPJF01000041_gene299	7.22e-221	612.0	COG0407@1|root,COG0407@2|Bacteria,1USM0@1239|Firmicutes,248G3@186801|Clostridia	186801|Clostridia	H	Methyltransferase MtaA CmuA family	hemE	-	4.1.1.37	ko:K01599	ko00860,ko01100,ko01110,map00860,map01100,map01110	M00121	R03197,R04972	RC00872	ko00000,ko00001,ko00002,ko01000	-	-	-	B12-binding,B12-binding_2,URO-D
NFNHFNFO_04110	33035.JPJF01000041_gene300	9.02e-37	124.0	COG1476@1|root,COG1476@2|Bacteria,1VEGF@1239|Firmicutes,24QPB@186801|Clostridia	186801|Clostridia	K	DNA-binding helix-turn-helix protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_04111	33035.JPJF01000041_gene301	4.09e-44	145.0	2CFZ9@1|root,307GU@2|Bacteria,1U1NF@1239|Firmicutes,258WC@186801|Clostridia,3Y22Q@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04112	33035.JPJF01000041_gene302	2.2e-274	752.0	COG0527@1|root,COG0527@2|Bacteria,1TPQJ@1239|Firmicutes,24811@186801|Clostridia,3XYJN@572511|Blautia	186801|Clostridia	E	Belongs to the aspartokinase family	lysC	-	2.7.2.4	ko:K00928	ko00260,ko00261,ko00270,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00260,map00261,map00270,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00017,M00018,M00033,M00525,M00526,M00527	R00480	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase,ACT,ACT_7
NFNHFNFO_04113	33035.JPJF01000041_gene303	0.0	2654.0	COG0642@1|root,COG0784@1|root,COG2202@1|root,COG0784@2|Bacteria,COG2202@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,3XZ5S@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
NFNHFNFO_04114	33035.JPJF01000041_gene304	0.0	972.0	COG1001@1|root,COG1001@2|Bacteria,1TP84@1239|Firmicutes,247KN@186801|Clostridia,3XZKC@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	ade	-	3.5.4.2	ko:K01486	ko00230,ko01100,map00230,map01100	-	R01244	RC00477	ko00000,ko00001,ko01000	-	-	-	Adenine_deam_C,Amidohydro_1
NFNHFNFO_04115	33035.JPJF01000041_gene305	0.0	1029.0	COG1012@1|root,COG1012@2|Bacteria,1TP4S@1239|Firmicutes,247W7@186801|Clostridia,3Y1YN@572511|Blautia	186801|Clostridia	C	Aldehyde dehydrogenase family	mmsA	-	1.2.1.18,1.2.1.27	ko:K00140	ko00280,ko00410,ko00562,ko00640,ko01100,ko01200,map00280,map00410,map00562,map00640,map01100,map01200	M00013	R00705,R00706,R00922,R00935	RC00004,RC02723,RC02817	ko00000,ko00001,ko00002,ko01000	-	-	-	Aldedh
NFNHFNFO_04116	33035.JPJF01000041_gene307	2.29e-177	497.0	COG2510@1|root,COG2510@2|Bacteria,1V3VG@1239|Firmicutes,247SX@186801|Clostridia,3XZSJ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K08978	-	-	-	-	ko00000,ko02000	2.A.7.2	-	-	EamA
NFNHFNFO_04117	742733.HMPREF9469_00349	7.15e-32	115.0	2AUBE@1|root,31JZ3@2|Bacteria,1V7V1@1239|Firmicutes,24NJE@186801|Clostridia,21ZXS@1506553|Lachnoclostridium	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF3788
NFNHFNFO_04118	1226325.HMPREF1548_06276	1.17e-103	302.0	COG1309@1|root,COG1309@2|Bacteria,1VAN5@1239|Firmicutes,25BR5@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_04119	1226325.HMPREF1548_06278	2.23e-197	558.0	COG1020@1|root,COG1020@2|Bacteria,1UQDB@1239|Firmicutes,25845@186801|Clostridia,36TFF@31979|Clostridiaceae	186801|Clostridia	Q	Condensation domain	-	-	-	-	-	-	-	-	-	-	-	-	Condensation
NFNHFNFO_04120	931276.Cspa_c05440	2.08e-55	180.0	COG0454@1|root,COG0456@2|Bacteria,1V3GG@1239|Firmicutes,25B37@186801|Clostridia,36W7Q@31979|Clostridiaceae	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_04121	33035.JPJF01000041_gene327	6.2e-53	168.0	2D3XN@1|root,32TFT@2|Bacteria,1VBF8@1239|Firmicutes,24NH8@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04122	33035.JPJF01000041_gene329	1.82e-168	476.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3Y1EY@572511|Blautia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_04123	33035.JPJF01000041_gene330	1.02e-114	333.0	COG1835@1|root,COG1835@2|Bacteria,1UG9X@1239|Firmicutes,24DXD@186801|Clostridia,3Y1V6@572511|Blautia	186801|Clostridia	I	ABC-2 family transporter protein	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_5
NFNHFNFO_04124	33035.JPJF01000041_gene333	3.8e-203	575.0	COG3290@1|root,COG3290@2|Bacteria,1TPZT@1239|Firmicutes,24DBC@186801|Clostridia,3Y0J1@572511|Blautia	186801|Clostridia	T	signal transduction protein with a C-terminal ATPase domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NFNHFNFO_04125	33035.JPJF01000041_gene334	2.21e-146	415.0	COG3279@1|root,COG3279@2|Bacteria,1UYV2@1239|Firmicutes,24F5U@186801|Clostridia,3Y1SH@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NFNHFNFO_04126	478749.BRYFOR_07491	1.84e-175	494.0	COG0583@1|root,COG0583@2|Bacteria,1TQWY@1239|Firmicutes,249N9@186801|Clostridia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_04127	401473.BDP_1352	1.77e-47	155.0	2E56Q@1|root,32ZZE@2|Bacteria,2H0BM@201174|Actinobacteria,4D1SU@85004|Bifidobacteriales	201174|Actinobacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04128	610130.Closa_3710	9.77e-68	213.0	COG1309@1|root,COG1309@2|Bacteria,1V7EC@1239|Firmicutes,24JXX@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_04129	1123075.AUDP01000031_gene2141	1.3e-86	258.0	COG0716@1|root,COG0716@2|Bacteria,1V465@1239|Firmicutes,24DQZ@186801|Clostridia,3WI5A@541000|Ruminococcaceae	186801|Clostridia	C	Flavodoxin	-	-	-	-	-	-	-	-	-	-	-	-	Flavodoxin_4
NFNHFNFO_04130	1123075.AUDP01000031_gene2140	3.28e-85	251.0	COG1917@1|root,COG1917@2|Bacteria,1TRVH@1239|Firmicutes,249JY@186801|Clostridia,3WGGH@541000|Ruminococcaceae	186801|Clostridia	S	Cupin domain	-	-	-	-	-	-	-	-	-	-	-	-	Cupin_2
NFNHFNFO_04131	1232446.BAIE02000006_gene2140	6.33e-196	551.0	COG1453@1|root,COG1453@2|Bacteria,1TQ5N@1239|Firmicutes,247SD@186801|Clostridia,267S2@186813|unclassified Clostridiales	186801|Clostridia	C	4Fe-4S dicluster domain	-	-	-	ko:K07079	-	-	-	-	ko00000	-	-	-	Aldo_ket_red,Fer4_17,Fer4_9
NFNHFNFO_04132	1196322.A370_00295	7.66e-141	402.0	COG0599@1|root,COG0599@2|Bacteria,1TQGP@1239|Firmicutes,24BPS@186801|Clostridia,36GUB@31979|Clostridiaceae	186801|Clostridia	S	PFAM Carboxymuconolactone decarboxylase	-	-	4.1.1.44	ko:K01607	ko00362,ko01100,ko01120,ko01220,map00362,map01100,map01120,map01220	-	R03470	RC00938	ko00000,ko00001,ko01000	-	-	-	CMD
NFNHFNFO_04133	658086.HMPREF0994_05664	8.8e-175	496.0	COG2267@1|root,COG2267@2|Bacteria,1V0IY@1239|Firmicutes,24BEP@186801|Clostridia,27MKS@186928|unclassified Lachnospiraceae	186801|Clostridia	I	alpha/beta hydrolase fold	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_1,Hydrolase_4
NFNHFNFO_04134	658086.HMPREF0994_05665	5.94e-86	257.0	COG1695@1|root,COG1695@2|Bacteria,1UYFE@1239|Firmicutes,24BYB@186801|Clostridia	186801|Clostridia	K	Transcriptional regulator PadR-like family	-	-	-	-	-	-	-	-	-	-	-	-	PadR
NFNHFNFO_04135	398512.JQKC01000013_gene1504	1e-98	292.0	COG0560@1|root,COG0560@2|Bacteria,1V9R7@1239|Firmicutes,25BCS@186801|Clostridia	186801|Clostridia	E	haloacid dehalogenase-like hydrolase	-	-	3.1.3.3	ko:K01079	ko00260,ko00680,ko01100,ko01120,ko01130,ko01200,ko01230,map00260,map00680,map01100,map01120,map01130,map01200,map01230	M00020	R00582	RC00017	ko00000,ko00001,ko00002,ko01000,ko01009	-	-	-	HAD
NFNHFNFO_04136	33035.JPJF01000009_gene1471	4.92e-97	285.0	COG0454@1|root,COG0456@2|Bacteria,1V7I8@1239|Firmicutes,24G1V@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_04137	1235802.C823_05791	2.47e-196	558.0	COG3290@1|root,COG3290@2|Bacteria,1UY02@1239|Firmicutes,24BV9@186801|Clostridia,25X4Y@186806|Eubacteriaceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NFNHFNFO_04138	1235792.C808_03951	4.74e-99	295.0	COG3279@1|root,COG3279@2|Bacteria,1VA5A@1239|Firmicutes,24C2K@186801|Clostridia,27TAQ@186928|unclassified Lachnospiraceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NFNHFNFO_04139	1235802.C823_05793	2.81e-36	127.0	COG3279@1|root,COG3279@2|Bacteria,1VAGQ@1239|Firmicutes	1239|Firmicutes	KT	Response regulator of the LytR AlgR family	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg
NFNHFNFO_04140	1121129.KB903373_gene532	9.06e-82	254.0	COG4667@1|root,COG4667@2|Bacteria,4NIX2@976|Bacteroidetes,2FM09@200643|Bacteroidia,22WX4@171551|Porphyromonadaceae	976|Bacteroidetes	S	Patatin-like phospholipase	-	-	-	-	-	-	-	-	-	-	-	-	Patatin
NFNHFNFO_04142	478749.BRYFOR_09472	3.14e-12	66.2	2DU6J@1|root,33P4K@2|Bacteria,1VKXU@1239|Firmicutes,24WA8@186801|Clostridia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04143	476272.RUMHYD_02631	3.2e-78	242.0	COG2186@1|root,COG2186@2|Bacteria,1V3VZ@1239|Firmicutes,25MUE@186801|Clostridia,3Y1KV@572511|Blautia	186801|Clostridia	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NFNHFNFO_04144	1122216.AUHW01000001_gene768	6.81e-148	422.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,4H24Q@909932|Negativicutes	909932|Negativicutes	G	Transketolase, thiamine diphosphate binding domain protein	-	-	-	-	-	-	-	-	-	-	-	-	Transketolase_N
NFNHFNFO_04145	666686.B1NLA3E_07270	1.38e-162	462.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,4HDCR@91061|Bacilli,1ZDCK@1386|Bacillus	91061|Bacilli	G	COG3958 Transketolase, C-terminal subunit	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
NFNHFNFO_04146	90371.CY43_16920	3.06e-59	198.0	COG2084@1|root,COG2084@2|Bacteria,1MUGU@1224|Proteobacteria,1SYGG@1236|Gammaproteobacteria,3ZK3D@590|Salmonella	1236|Gammaproteobacteria	I	Catalyzes the reduction of tatronate semialdehyde to D- glycerate	garR	GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575	1.1.1.31,1.1.1.60	ko:K00020,ko:K00042	ko00280,ko00630,ko01100,map00280,map00630,map01100	-	R01745,R01747,R05066	RC00099	ko00000,ko00001,ko01000	-	-	iNRG857_1313.NRG857_15520	NAD_binding_11,NAD_binding_2
NFNHFNFO_04147	742733.HMPREF9469_05919	6.34e-96	294.0	28H7K@1|root,2Z7JT@2|Bacteria,1UPH1@1239|Firmicutes,249YA@186801|Clostridia,21ZS1@1506553|Lachnoclostridium	186801|Clostridia	P	2-keto-3-deoxygluconate permease	kdgT	-	-	ko:K02526	-	-	-	-	ko00000,ko02000	2.A.10.1	-	-	KdgT
NFNHFNFO_04148	457421.CBFG_00086	7.54e-125	374.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,24EHA@186801|Clostridia	186801|Clostridia	Q	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
NFNHFNFO_04149	476272.RUMHYD_02143	9.76e-196	546.0	COG1052@1|root,COG1052@2|Bacteria,1TPCX@1239|Firmicutes,248UR@186801|Clostridia,3XYQ8@572511|Blautia	186801|Clostridia	CH	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family	-	-	1.1.1.29	ko:K00018	ko00260,ko00630,ko00680,ko01100,ko01110,ko01120,ko01130,ko01200,map00260,map00630,map00680,map01100,map01110,map01120,map01130,map01200	M00346	R00717,R01388	RC00031,RC00042	ko00000,ko00001,ko00002,ko01000	-	-	-	2-Hacid_dh,2-Hacid_dh_C
NFNHFNFO_04150	658659.HMPREF0983_02825	5.08e-199	555.0	COG2207@1|root,COG2207@2|Bacteria,1VCUV@1239|Firmicutes,3VRY1@526524|Erysipelotrichia	526524|Erysipelotrichia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18
NFNHFNFO_04151	1211819.CALK01000029_gene2037	3.38e-144	409.0	COG1028@1|root,COG1028@2|Bacteria,1TR1J@1239|Firmicutes,3VP29@526524|Erysipelotrichia	526524|Erysipelotrichia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NFNHFNFO_04152	1123075.AUDP01000056_gene2462	6.43e-265	733.0	COG0534@1|root,COG0534@2|Bacteria,1TQ56@1239|Firmicutes,248YU@186801|Clostridia,3WI10@541000|Ruminococcaceae	186801|Clostridia	V	MATE efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_04153	33035.JPJF01000067_gene3537	1.09e-252	698.0	COG0027@1|root,COG0027@2|Bacteria,1VR1C@1239|Firmicutes,25M0G@186801|Clostridia,3XZT7@572511|Blautia	186801|Clostridia	F	ATP-grasp domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
NFNHFNFO_04154	1121115.AXVN01000022_gene1728	9.01e-117	347.0	COG0399@1|root,COG0399@2|Bacteria,1TZB6@1239|Firmicutes,249QE@186801|Clostridia,3Y0S8@572511|Blautia	186801|Clostridia	M	UDP-4-amino-4-deoxy-L-arabinose aminotransferase	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04155	1123075.AUDP01000009_gene1226	2.91e-161	458.0	COG0463@1|root,COG0463@2|Bacteria,1TRFA@1239|Firmicutes,249CR@186801|Clostridia,3WJSA@541000|Ruminococcaceae	186801|Clostridia	M	Glycosyl transferase family 2	-	-	2.4.2.53	ko:K10012	ko00520,ko01503,map00520,map01503	M00721,M00761	R07661	RC00005,RC02954	ko00000,ko00001,ko00002,ko01000,ko01005,ko02000	4.D.2.1.8	GT2	-	Glycos_transf_2
NFNHFNFO_04156	476272.RUMHYD_01225	3.72e-45	149.0	COG0697@1|root,COG0697@2|Bacteria,1UHS0@1239|Firmicutes,25FFB@186801|Clostridia,3Y0C7@572511|Blautia	186801|Clostridia	EG	spore germination	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_04157	1123075.AUDP01000009_gene1228	1.49e-50	162.0	COG2076@1|root,COG2076@2|Bacteria,1VFDI@1239|Firmicutes,24S4I@186801|Clostridia,3WKQ8@541000|Ruminococcaceae	186801|Clostridia	P	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_04158	33035.JPJF01000067_gene3539	1.12e-249	687.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,3XZ4N@572511|Blautia	186801|Clostridia	E	Belongs to the DegT DnrJ EryC1 family	wecE	-	2.6.1.59	ko:K02805	-	-	-	-	ko00000,ko01000,ko01007	-	-	-	DegT_DnrJ_EryC1
NFNHFNFO_04159	33035.JPJF01000067_gene3540	1.73e-260	774.0	COG0860@1|root,COG5263@1|root,COG0860@2|Bacteria,COG5263@2|Bacteria,1V0DN@1239|Firmicutes,24BCJ@186801|Clostridia,3Y28D@572511|Blautia	186801|Clostridia	M	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_3,CW_binding_1,Glucosaminidase
NFNHFNFO_04160	536232.CLM_1016	1.45e-95	286.0	COG1073@1|root,COG1073@2|Bacteria,1U9AI@1239|Firmicutes,24B6Z@186801|Clostridia,36F9A@31979|Clostridiaceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K06889	-	-	-	-	ko00000	-	-	-	Hydrolase_4
NFNHFNFO_04161	1336241.JAEB01000003_gene360	2.94e-209	596.0	COG4799@1|root,COG4799@2|Bacteria,1UJNR@1239|Firmicutes,25F6T@186801|Clostridia	186801|Clostridia	I	PFAM carboxyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Carboxyl_trans
NFNHFNFO_04162	1007103.AFHW01000010_gene6080	8.14e-75	254.0	COG0331@1|root,COG2070@1|root,COG3321@1|root,COG0331@2|Bacteria,COG2070@2|Bacteria,COG3321@2|Bacteria,1UG0E@1239|Firmicutes,4HTY4@91061|Bacilli,274JP@186822|Paenibacillaceae	91061|Bacilli	IQ	Acyl transferase domain	-	-	-	ko:K15329	-	-	-	-	ko00000,ko01008	-	-	-	Acyl_transf_1
NFNHFNFO_04163	999413.HMPREF1094_00884	1.64e-05	49.7	COG1476@1|root,COG1476@2|Bacteria	2|Bacteria	K	sequence-specific DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	DUF4065,HTH_19,HTH_3
NFNHFNFO_04164	1163671.JAGI01000002_gene2766	6.38e-73	229.0	COG3279@1|root,COG3279@2|Bacteria,1V0QJ@1239|Firmicutes,24E66@186801|Clostridia,36VKK@31979|Clostridiaceae	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NFNHFNFO_04165	500632.CLONEX_00742	1.14e-35	144.0	COG3290@1|root,COG3290@2|Bacteria,1V368@1239|Firmicutes,24B4K@186801|Clostridia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NFNHFNFO_04168	411462.DORLON_00355	7.14e-292	802.0	COG0168@1|root,COG0168@2|Bacteria,1TQ4S@1239|Firmicutes,247Q3@186801|Clostridia,27V2F@189330|Dorea	186801|Clostridia	P	Cation transport protein	ktrB	-	-	ko:K03498	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkH
NFNHFNFO_04169	1280698.AUJS01000009_gene757	2.47e-137	390.0	COG0569@1|root,COG0569@2|Bacteria,1TQ9H@1239|Firmicutes,249C2@186801|Clostridia,27VJC@189330|Dorea	186801|Clostridia	P	TrkA-C domain	-	-	-	ko:K03499	-	-	-	-	ko00000,ko02000	2.A.38.1,2.A.38.4	-	-	TrkA_C,TrkA_N
NFNHFNFO_04170	411470.RUMGNA_02701	7.83e-07	52.0	COG2755@1|root,COG2755@2|Bacteria,1VCTB@1239|Firmicutes,24GZV@186801|Clostridia,3Y1E4@572511|Blautia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NFNHFNFO_04171	411459.RUMOBE_02286	2.85e-30	112.0	COG1595@1|root,COG1595@2|Bacteria,1V22M@1239|Firmicutes,24EDG@186801|Clostridia,3Y0NG@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r4,Sigma70_r4_2
NFNHFNFO_04172	469604.HMPREF0946_01167	2.93e-153	437.0	COG0697@1|root,COG0697@2|Bacteria,37BIG@32066|Fusobacteria	32066|Fusobacteria	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_04173	1045858.Bint_2799	1.45e-66	213.0	COG0673@1|root,COG0673@2|Bacteria	2|Bacteria	S	inositol 2-dehydrogenase activity	yisS	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_04174	180332.JTGN01000011_gene650	2.38e-54	189.0	2A542@1|root,30TSQ@2|Bacteria,1V4Q2@1239|Firmicutes,24ISW@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04175	180332.JTGN01000011_gene649	1.29e-35	135.0	2CJWU@1|root,32SAY@2|Bacteria,1V3P4@1239|Firmicutes,24SCQ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04176	411461.DORFOR_00973	8.56e-218	627.0	COG1368@1|root,COG1368@2|Bacteria,1UUVI@1239|Firmicutes,24AGB@186801|Clostridia,27UXQ@189330|Dorea	186801|Clostridia	M	GBS Bsp-like repeat	-	-	2.7.8.20	ko:K01002	ko01100,map01100	-	-	-	ko00000,ko01000	-	-	-	GBS_Bsp-like,Sulfatase
NFNHFNFO_04177	665950.HMPREF1025_02917	8.08e-86	253.0	28IAH@1|root,2Z8D3@2|Bacteria,1TRGI@1239|Firmicutes,24U6D@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04178	665950.HMPREF1025_02918	5.58e-76	226.0	COG3436@1|root,COG3436@2|Bacteria,1V7U9@1239|Firmicutes,24K4W@186801|Clostridia,27P7R@186928|unclassified Lachnospiraceae	186801|Clostridia	L	IS66 Orf2 like protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
NFNHFNFO_04179	665950.HMPREF1025_02919	1.2e-24	105.0	COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,251Y5@186801|Clostridia,27UCA@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
NFNHFNFO_04180	665950.HMPREF1025_02919	3.72e-226	633.0	COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,251Y5@186801|Clostridia,27UCA@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
NFNHFNFO_04181	33035.JPJF01000028_gene2795	1.67e-190	532.0	COG1533@1|root,COG1533@2|Bacteria,1TQA6@1239|Firmicutes,24A2T@186801|Clostridia,3Y02D@572511|Blautia	186801|Clostridia	L	Domain of unknown function (DUF1848)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1848
NFNHFNFO_04182	33035.JPJF01000028_gene2794	7.17e-242	667.0	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,24A9E@186801|Clostridia,3XZW7@572511|Blautia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
NFNHFNFO_04183	33035.JPJF01000028_gene2793	3.12e-176	492.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3XYM7@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	1.1.1.69	ko:K00046	-	-	-	-	ko00000,ko01000	-	-	-	adh_short,adh_short_C2
NFNHFNFO_04184	33035.JPJF01000028_gene2792	0.0	919.0	COG1070@1|root,COG1070@2|Bacteria,1TQ1I@1239|Firmicutes,247NR@186801|Clostridia,3XZDA@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	2.7.1.17	ko:K00854	ko00040,ko01100,map00040,map01100	M00014	R01639	RC00002,RC00538	ko00000,ko00001,ko00002,ko01000	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_04185	1195236.CTER_1945	8.74e-59	207.0	COG4219@1|root,COG4219@2|Bacteria,1TQ0K@1239|Firmicutes,24AVI@186801|Clostridia,3WIKG@541000|Ruminococcaceae	186801|Clostridia	KT	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
NFNHFNFO_04186	180332.JTGN01000003_gene1887	2.42e-53	170.0	COG3682@1|root,COG3682@2|Bacteria,1V7DH@1239|Firmicutes,24JAQ@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	Penicillinase_R
NFNHFNFO_04187	33035.JPJF01000014_gene4908	4.73e-135	410.0	COG0612@1|root,COG0612@2|Bacteria,1VI33@1239|Firmicutes,25KCP@186801|Clostridia,3Y11H@572511|Blautia	186801|Clostridia	N	Glycosyl hydrolase family 98	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_98C,Glyco_hydro_98M
NFNHFNFO_04188	33035.JPJF01000024_gene3187	3.46e-93	274.0	COG1595@1|root,COG1595@2|Bacteria,1VACS@1239|Firmicutes,24KS7@186801|Clostridia,3Y0EM@572511|Blautia	186801|Clostridia	K	COG COG1595 DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_04189	33035.JPJF01000024_gene3188	5.36e-255	708.0	28NHG@1|root,2ZBJ9@2|Bacteria,1V1QG@1239|Firmicutes,24GQ1@186801|Clostridia,3Y0RS@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4179
NFNHFNFO_04190	33035.JPJF01000024_gene3189	5.84e-316	859.0	COG0104@1|root,COG0104@2|Bacteria,1TQ4C@1239|Firmicutes,247RN@186801|Clostridia,3XYKX@572511|Blautia	186801|Clostridia	F	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP	purA	-	6.3.4.4	ko:K01939	ko00230,ko00250,ko01100,map00230,map00250,map01100	M00049	R01135	RC00458,RC00459	ko00000,ko00001,ko00002,ko01000	-	-	-	Adenylsucc_synt
NFNHFNFO_04191	1232452.BAIB02000007_gene1794	4.4e-99	290.0	COG3464@1|root,COG3464@2|Bacteria,1V6WR@1239|Firmicutes,24J2D@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3,zf-ISL3
NFNHFNFO_04192	742765.HMPREF9457_03545	8.04e-203	572.0	COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,251Y5@186801|Clostridia,27XE5@189330|Dorea	186801|Clostridia	L	Transposase C of IS166 homeodomain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
NFNHFNFO_04193	457412.RSAG_01399	2.58e-307	850.0	COG5421@1|root,COG5421@2|Bacteria,1TPAA@1239|Firmicutes,2492T@186801|Clostridia,3WH72@541000|Ruminococcaceae	186801|Clostridia	L	Transposase DDE domain	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_1
NFNHFNFO_04194	1321784.HMPREF1987_01584	7.08e-175	493.0	COG2801@1|root,COG2801@2|Bacteria,1TQEG@1239|Firmicutes,25B5A@186801|Clostridia	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_21,HTH_28,rve,rve_2
NFNHFNFO_04195	1069533.Sinf_0130	2.05e-112	328.0	COG2963@1|root,COG2963@2|Bacteria,1V1QC@1239|Firmicutes,4HH7E@91061|Bacilli	91061|Bacilli	L	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_28,HTH_Tnp_1
NFNHFNFO_04196	180332.JTGN01000018_gene79	2.86e-142	426.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TRXY@1239|Firmicutes,24BYW@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NFNHFNFO_04197	180332.JTGN01000018_gene78	1.06e-172	510.0	COG2972@1|root,COG2972@2|Bacteria,1UYIY@1239|Firmicutes,24ACA@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase,dCache_1
NFNHFNFO_04198	180332.JTGN01000018_gene75	2.35e-207	587.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24C14@186801|Clostridia	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_04199	33035.JPJF01000051_gene772	5.54e-267	733.0	COG1473@1|root,COG1473@2|Bacteria,1TQ7B@1239|Firmicutes,247ZP@186801|Clostridia,3Y0Z9@572511|Blautia	186801|Clostridia	S	Peptidase dimerisation domain	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
NFNHFNFO_04200	33035.JPJF01000051_gene773	2.2e-115	330.0	COG0717@1|root,COG0717@2|Bacteria,1V1BE@1239|Firmicutes,24A3M@186801|Clostridia	186801|Clostridia	F	Belongs to the dCTP deaminase family	dcd	-	3.5.4.13	ko:K01494	ko00240,ko01100,map00240,map01100	M00053	R00568,R02325	RC00074	ko00000,ko00001,ko00002,ko01000	-	-	-	DCD,dUTPase
NFNHFNFO_04201	97139.C824_00912	9.73e-128	383.0	COG1593@1|root,COG1593@2|Bacteria,1UIAS@1239|Firmicutes,25EFX@186801|Clostridia,36UPB@31979|Clostridiaceae	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporter, DctM component	-	-	-	-	-	-	-	-	-	-	-	-	DctM
NFNHFNFO_04202	395495.Lcho_0822	0.000831	47.0	COG1593@1|root,COG3090@1|root,COG1593@2|Bacteria,COG3090@2|Bacteria,1MU0F@1224|Proteobacteria,2VHFG@28216|Betaproteobacteria,1KK5Z@119065|unclassified Burkholderiales	28216|Betaproteobacteria	G	PFAM Tripartite ATP-independent periplasmic transporter DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctM,DctQ
NFNHFNFO_04203	573413.Spirs_4174	2.37e-108	327.0	COG1638@1|root,COG1638@2|Bacteria,2J792@203691|Spirochaetes	203691|Spirochaetes	G	extracellular solute-binding protein, family 7	-	-	-	ko:K21395	-	-	-	-	ko00000,ko02000	2.A.56.1	-	-	DctP
NFNHFNFO_04204	1232453.BAIF02000003_gene1370	8.85e-64	211.0	COG3835@1|root,COG3835@2|Bacteria,1UYBM@1239|Firmicutes,249BJ@186801|Clostridia,26BED@186813|unclassified Clostridiales	186801|Clostridia	KT	Putative sugar diacid recognition	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	Diacid_rec,HTH_30
NFNHFNFO_04205	556261.HMPREF0240_03261	1.21e-34	129.0	COG3835@1|root,COG3835@2|Bacteria,1UYBM@1239|Firmicutes,249BJ@186801|Clostridia,36HQW@31979|Clostridiaceae	186801|Clostridia	KT	PucR C-terminal helix-turn-helix domain	-	-	-	ko:K02647	-	-	-	-	ko00000,ko03000	-	-	-	Diacid_rec,HTH_30
NFNHFNFO_04206	556261.HMPREF0240_03262	1.74e-169	486.0	COG0407@1|root,COG0407@2|Bacteria,1W13C@1239|Firmicutes,24Z3X@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_04207	1226325.HMPREF1548_01717	1.01e-40	143.0	2DBC6@1|root,2Z8BZ@2|Bacteria,1TQXM@1239|Firmicutes,2484N@186801|Clostridia,36I8F@31979|Clostridiaceae	186801|Clostridia	S	Replication initiator protein A (RepA) N-terminus	-	-	-	-	-	-	-	-	-	-	-	-	RepA_N
NFNHFNFO_04208	1226325.HMPREF1548_01681	6.84e-316	864.0	COG2186@1|root,COG2188@1|root,COG2186@2|Bacteria,COG2188@2|Bacteria,1TSP3@1239|Firmicutes,24DQE@186801|Clostridia,36DRH@31979|Clostridiaceae	186801|Clostridia	K	Transcriptional regulator, GntR family	-	-	-	-	-	-	-	-	-	-	-	-	GntR
NFNHFNFO_04209	1226325.HMPREF1548_01680	0.0	1009.0	COG2199@1|root,COG3437@1|root,COG2199@2|Bacteria,COG3437@2|Bacteria,1UQJH@1239|Firmicutes,248UM@186801|Clostridia,36DPS@31979|Clostridiaceae	186801|Clostridia	T	domain protein	rpfG3	-	-	ko:K07814	-	-	-	-	ko00000,ko02022	-	-	-	GAF_2,GGDEF,HD,HD_5,Response_reg
NFNHFNFO_04210	1226325.HMPREF1548_01679	2.2e-79	236.0	COG2198@1|root,COG2198@2|Bacteria,1VG8R@1239|Firmicutes,24QS0@186801|Clostridia	186801|Clostridia	T	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Hpt
NFNHFNFO_04211	742741.HMPREF9475_03505	0.0	1468.0	COG0642@1|root,COG0784@1|root,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,21YR0@1506553|Lachnoclostridium	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Response_reg
NFNHFNFO_04212	1226325.HMPREF1548_01675	7.69e-26	101.0	COG1595@1|root,COG1595@2|Bacteria,1VW37@1239|Firmicutes,25AWT@186801|Clostridia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r4_2
NFNHFNFO_04213	33035.JPJF01000051_gene775	0.0	2390.0	COG0046@1|root,COG0047@1|root,COG0046@2|Bacteria,COG0047@2|Bacteria,1TPAS@1239|Firmicutes,247W2@186801|Clostridia,3XYY2@572511|Blautia	186801|Clostridia	F	bifunctional enzyme phosphoribosylformylglycinamidine (FGAM) synthase (synthetase domain glutamine amidotransferase domain)	purL	-	6.3.5.3	ko:K01952	ko00230,ko01100,ko01110,ko01130,map00230,map01100,map01110,map01130	M00048	R04463	RC00010,RC01160	ko00000,ko00001,ko00002,ko01000	-	-	-	AIRS,AIRS_C,GATase_5
NFNHFNFO_04214	411902.CLOBOL_06543	0.000146	49.7	COG2865@1|root,COG2865@2|Bacteria,1TRTZ@1239|Firmicutes,25CHW@186801|Clostridia,2208Y@1506553|Lachnoclostridium	186801|Clostridia	K	Putative ATP-dependent DNA helicase recG C-terminal	-	-	-	-	-	-	-	-	-	-	-	-	AlbA_2,HATPase_c_4,HTH_24
NFNHFNFO_04215	742733.HMPREF9469_01398	1.1e-112	365.0	COG1203@1|root,COG1203@2|Bacteria,1TQ9B@1239|Firmicutes,248UE@186801|Clostridia,21Z27@1506553|Lachnoclostridium	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04216	1211819.CALK01000021_gene714	1.76e-117	346.0	COG3649@1|root,COG3649@2|Bacteria	2|Bacteria	L	CRISPR-associated protein Cas7	cas7	-	-	ko:K19115	-	-	-	-	ko00000,ko02048	-	-	-	Cas_Cas7
NFNHFNFO_04217	742733.HMPREF9469_01400	6.11e-28	128.0	2ED7F@1|root,33741@2|Bacteria	2|Bacteria	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04220	33035.JPJF01000051_gene776	2.93e-276	758.0	COG0738@1|root,COG0738@2|Bacteria,1TQPE@1239|Firmicutes,24AF8@186801|Clostridia,3XYNH@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1
NFNHFNFO_04221	33035.JPJF01000051_gene777	4.66e-200	555.0	COG0583@1|root,COG0583@2|Bacteria,1TRJK@1239|Firmicutes,24AY4@186801|Clostridia,3XZ9N@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_04222	33035.JPJF01000051_gene778	1.27e-151	429.0	COG4608@1|root,COG4608@2|Bacteria,1V36J@1239|Firmicutes,24A3N@186801|Clostridia,3XZ3G@572511|Blautia	186801|Clostridia	E	Psort location CytoplasmicMembrane, score 9.49	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_04223	33035.JPJF01000051_gene779	2.78e-160	452.0	COG0444@1|root,COG0444@2|Bacteria,1TP6E@1239|Firmicutes,24B9N@186801|Clostridia,3XZCY@572511|Blautia	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_04224	33035.JPJF01000051_gene780	0.0	933.0	COG0747@1|root,COG0747@2|Bacteria,1TQ6S@1239|Firmicutes,248A3@186801|Clostridia,3XZGV@572511|Blautia	186801|Clostridia	E	Psort location Cellwall, score	-	-	-	ko:K02035	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	SBP_bac_5
NFNHFNFO_04225	33035.JPJF01000051_gene781	2.95e-178	499.0	COG1173@1|root,COG1173@2|Bacteria,1TP4R@1239|Firmicutes,2489T@186801|Clostridia,3XZRV@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02034	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1,OppC_N
NFNHFNFO_04226	33035.JPJF01000051_gene782	1.86e-199	555.0	COG0601@1|root,COG0601@2|Bacteria,1TP1S@1239|Firmicutes,247IP@186801|Clostridia,3XZG8@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02033	ko02024,map02024	M00239	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.5	-	-	BPD_transp_1
NFNHFNFO_04227	33035.JPJF01000051_gene783	0.0	1019.0	COG0500@1|root,COG3608@1|root,COG2226@2|Bacteria,COG3608@2|Bacteria,1V3EF@1239|Firmicutes,24IK6@186801|Clostridia,3Y2A4@572511|Blautia	186801|Clostridia	Q	Succinylglutamate desuccinylase / Aspartoacylase family	-	-	-	ko:K06987	-	-	-	-	ko00000	-	-	-	AstE_AspA,Methyltransf_11
NFNHFNFO_04228	33035.JPJF01000051_gene784	7.81e-165	463.0	COG0500@1|root,COG2226@2|Bacteria,1UY28@1239|Firmicutes,25KD5@186801|Clostridia,3Y089@572511|Blautia	186801|Clostridia	Q	ubiE/COQ5 methyltransferase family	-	-	-	-	-	-	-	-	-	-	-	-	Methyltransf_11
NFNHFNFO_04229	33035.JPJF01000051_gene785	1.07e-79	238.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,24J8Y@186801|Clostridia,3Y05K@572511|Blautia	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
NFNHFNFO_04230	1423807.BACO01000036_gene1050	3.04e-139	408.0	COG0673@1|root,COG0673@2|Bacteria,1U4A4@1239|Firmicutes,4HBTG@91061|Bacilli,3F94F@33958|Lactobacillaceae	91061|Bacilli	S	Oxidoreductase family, NAD-binding Rossmann fold	-	-	1.1.1.18,1.1.1.369	ko:K00010	ko00521,ko00562,ko01100,ko01120,ko01130,map00521,map00562,map01100,map01120,map01130	-	R01183,R09951	RC00182	ko00000,ko00001,ko01000	-	-	-	GFO_IDH_MocA
NFNHFNFO_04231	33035.JPJF01000051_gene786	8.41e-163	457.0	COG3622@1|root,COG3622@2|Bacteria,1V3V8@1239|Firmicutes,25C7T@186801|Clostridia	186801|Clostridia	G	Belongs to the hyi family	-	-	5.3.1.22	ko:K01816	ko00630,ko01100,map00630,map01100	-	R01394	RC00511	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
NFNHFNFO_04232	428125.CLOLEP_03153	5.98e-133	390.0	COG1063@1|root,COG1063@2|Bacteria,1TQKZ@1239|Firmicutes,24BU4@186801|Clostridia	186801|Clostridia	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
NFNHFNFO_04233	33035.JPJF01000072_gene4380	1.1e-21	105.0	COG1653@1|root,COG1653@2|Bacteria,1TT8P@1239|Firmicutes,24DVQ@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_04234	545695.TREAZ_1656	1.07e-98	298.0	COG0395@1|root,COG0395@2|Bacteria,2JBHA@203691|Spirochaetes	203691|Spirochaetes	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_04235	545695.TREAZ_1657	2.33e-99	301.0	COG1175@1|root,COG1175@2|Bacteria,2J6CI@203691|Spirochaetes	203691|Spirochaetes	G	PFAM Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K15771	ko02010,map02010	M00207,M00491	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.16,3.A.1.1.2	-	-	BPD_transp_1
NFNHFNFO_04236	545695.TREAZ_1658	1.47e-58	200.0	COG1609@1|root,COG1609@2|Bacteria,2J7P1@203691|Spirochaetes	203691|Spirochaetes	K	Periplasmic binding protein LacI transcriptional regulator	-	-	-	ko:K02529,ko:K05499	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_04238	33035.JPJF01000051_gene787	0.0	1477.0	COG1199@1|root,COG1199@2|Bacteria,1TPNB@1239|Firmicutes,248ZI@186801|Clostridia,3XYZ7@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	dinG	-	3.1.12.1,3.6.4.12	ko:K07464,ko:K10844	ko03022,ko03420,map03022,map03420	M00290	-	-	ko00000,ko00001,ko00002,ko01000,ko02048,ko03021,ko03400	-	-	-	DEAD,DEAD_2,HBB,Helicase_C_2,PDDEXK_1
NFNHFNFO_04241	33035.JPJF01000051_gene788	3.13e-43	141.0	COG1925@1|root,COG1925@2|Bacteria,1VEJ5@1239|Firmicutes,24R2F@186801|Clostridia,3Y0M0@572511|Blautia	186801|Clostridia	G	phosphocarrier protein HPr	-	-	-	-	-	-	-	-	-	-	-	-	PTS-HPr
NFNHFNFO_04242	33035.JPJF01000051_gene789	1.68e-191	532.0	COG0489@1|root,COG0489@2|Bacteria,1TQ34@1239|Firmicutes,24817@186801|Clostridia,3XYU0@572511|Blautia	186801|Clostridia	D	Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP	mrp	-	-	-	-	-	-	-	-	-	-	-	ParA
NFNHFNFO_04243	33035.JPJF01000051_gene790	1.99e-68	208.0	COG1937@1|root,COG1937@2|Bacteria,1VA7S@1239|Firmicutes,24NNH@186801|Clostridia,3Y061@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NFNHFNFO_04244	33035.JPJF01000051_gene791	1.27e-47	152.0	2ES6S@1|root,33JRI@2|Bacteria,1VQGH@1239|Firmicutes,24WUX@186801|Clostridia,3Y0HU@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04245	411902.CLOBOL_03285	8.07e-69	220.0	COG2015@1|root,COG2015@2|Bacteria,1TR7Q@1239|Firmicutes,248SN@186801|Clostridia,2232Y@1506553|Lachnoclostridium	186801|Clostridia	Q	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
NFNHFNFO_04246	411902.CLOBOL_03285	2e-131	384.0	COG2015@1|root,COG2015@2|Bacteria,1TR7Q@1239|Firmicutes,248SN@186801|Clostridia,2232Y@1506553|Lachnoclostridium	186801|Clostridia	Q	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Alkyl_sulf_C,Alkyl_sulf_dimr,Lactamase_B
NFNHFNFO_04247	411902.CLOBOL_03284	3.15e-123	355.0	COG0775@1|root,COG0775@2|Bacteria,1U7WK@1239|Firmicutes,247U5@186801|Clostridia	186801|Clostridia	E	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively	-	-	3.2.2.9	ko:K01243	ko00270,ko01100,ko01230,map00270,map01100,map01230	M00034,M00609	R00194,R01401	RC00063,RC00318	ko00000,ko00001,ko00002,ko01000	-	-	-	PNP_UDP_1
NFNHFNFO_04248	33035.JPJF01000051_gene792	1.42e-127	363.0	COG0503@1|root,COG0503@2|Bacteria,1V1DU@1239|Firmicutes,249VC@186801|Clostridia,3XZCM@572511|Blautia	186801|Clostridia	F	Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis	xpt	-	2.4.2.22	ko:K03816	ko00230,ko01100,ko01110,map00230,map01100,map01110	-	R01229,R02142	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
NFNHFNFO_04249	33035.JPJF01000051_gene793	1.34e-110	319.0	COG4720@1|root,COG4720@2|Bacteria,1VBJP@1239|Firmicutes,25CJQ@186801|Clostridia	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	-	-	-	-	-	-	-	-	-	ECF-ribofla_trS
NFNHFNFO_04250	33035.JPJF01000051_gene794	1.48e-99	289.0	COG0454@1|root,COG0456@2|Bacteria,1VDD6@1239|Firmicutes,24NEN@186801|Clostridia,3Y0NK@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
NFNHFNFO_04251	33035.JPJF01000051_gene795	2.07e-36	123.0	29VFG@1|root,30GWP@2|Bacteria,1UGSZ@1239|Firmicutes,25PBW@186801|Clostridia,3Y25I@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04252	33035.JPJF01000051_gene796	9.85e-296	809.0	COG0389@1|root,COG0389@2|Bacteria,1TP42@1239|Firmicutes,24855@186801|Clostridia,3XYYM@572511|Blautia	186801|Clostridia	L	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII	dinB	-	2.7.7.7	ko:K02346	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	IMS,IMS_C,IMS_HHH
NFNHFNFO_04253	33035.JPJF01000051_gene797	2.91e-276	756.0	COG1408@1|root,COG1408@2|Bacteria,1TS43@1239|Firmicutes,248XA@186801|Clostridia,3XZND@572511|Blautia	186801|Clostridia	S	Calcineurin-like phosphoesterase	-	-	-	ko:K07098	-	-	-	-	ko00000	-	-	-	Metallophos
NFNHFNFO_04254	411902.CLOBOL_01856	9.69e-171	488.0	COG0520@1|root,COG0520@2|Bacteria,1TQ1W@1239|Firmicutes,249CS@186801|Clostridia,21Z7G@1506553|Lachnoclostridium	186801|Clostridia	E	Cysteine desulfurase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_5
NFNHFNFO_04255	33035.JPJF01000051_gene798	3.27e-218	605.0	COG0709@1|root,COG0709@2|Bacteria,1TQCJ@1239|Firmicutes,247NS@186801|Clostridia,3XZ8H@572511|Blautia	186801|Clostridia	H	Synthesizes selenophosphate from selenide and ATP	selD	-	2.7.9.3	ko:K01008	ko00450,ko01100,map00450,map01100	-	R03595	RC00002,RC02878	ko00000,ko00001,ko01000,ko03016	-	-	-	AIRS,AIRS_C
NFNHFNFO_04256	33035.JPJF01000051_gene800	1.62e-179	499.0	COG0708@1|root,COG0708@2|Bacteria,1TPFB@1239|Firmicutes,24849@186801|Clostridia,3XYR4@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 9.98	xth	-	3.1.11.2	ko:K01142	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	Exo_endo_phos
NFNHFNFO_04257	33035.JPJF01000051_gene801	3.26e-111	320.0	COG3663@1|root,COG3663@2|Bacteria,1V6GI@1239|Firmicutes,24HD8@186801|Clostridia,3Y0AE@572511|Blautia	186801|Clostridia	L	Uracil DNA glycosylase superfamily	-	-	3.2.2.28	ko:K03649	ko03410,map03410	-	-	-	ko00000,ko00001,ko01000,ko03400	-	-	-	UDG
NFNHFNFO_04258	33035.JPJF01000051_gene802	0.0	941.0	COG0034@1|root,COG0034@2|Bacteria,1TPH3@1239|Firmicutes,247RF@186801|Clostridia,3XYNA@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purF_1	-	2.4.2.14	ko:K00764	ko00230,ko00250,ko01100,ko01110,ko01130,map00230,map00250,map01100,map01110,map01130	M00048	R01072	RC00010,RC02724,RC02752	ko00000,ko00001,ko00002,ko01000,ko01002	-	-	-	GATase_7,Pribosyltran
NFNHFNFO_04259	33035.JPJF01000014_gene4786	5.01e-135	389.0	COG2253@1|root,COG2253@2|Bacteria,1TSFX@1239|Firmicutes,24C3A@186801|Clostridia,3Y1P3@572511|Blautia	186801|Clostridia	S	Nucleotidyl transferase AbiEii toxin, Type IV TA system	-	-	-	-	-	-	-	-	-	-	-	-	AbiEii
NFNHFNFO_04260	1235792.C808_02217	2.6e-97	288.0	COG5340@1|root,COG5340@2|Bacteria,1UGVN@1239|Firmicutes,24AA8@186801|Clostridia,27TJ1@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Transcriptional regulator, AbiEi antitoxin	-	-	-	-	-	-	-	-	-	-	-	-	AbiEi_4
NFNHFNFO_04261	33035.JPJF01000051_gene803	4.49e-155	437.0	COG1082@1|root,COG1082@2|Bacteria,1VFCG@1239|Firmicutes,24D46@186801|Clostridia,3Y01H@572511|Blautia	186801|Clostridia	L	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NFNHFNFO_04262	33035.JPJF01000051_gene804	7.15e-197	546.0	COG1284@1|root,COG1284@2|Bacteria,1TRBT@1239|Firmicutes,248B1@186801|Clostridia,3XYZS@572511|Blautia	186801|Clostridia	S	Uncharacterized protein conserved in bacteria (DUF2179)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2179,YitT_membrane
NFNHFNFO_04263	33035.JPJF01000051_gene805	4.71e-238	654.0	COG1712@1|root,COG1712@2|Bacteria,1TQ4R@1239|Firmicutes,2499V@186801|Clostridia,3XYQU@572511|Blautia	186801|Clostridia	E	Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate	ddh	-	1.4.1.16	ko:K03340	ko00300,ko01100,ko01110,ko01230,map00300,map01100,map01110,map01230	M00526	R02755	RC00006	ko00000,ko00001,ko00002,ko01000	-	-	-	DAPDH_C,DapB_N
NFNHFNFO_04264	33035.JPJF01000051_gene806	1.33e-294	807.0	COG0733@1|root,COG0733@2|Bacteria,1TP6B@1239|Firmicutes,2485D@186801|Clostridia,3Y12F@572511|Blautia	186801|Clostridia	S	Sodium:neurotransmitter symporter family	-	-	-	ko:K03308	-	-	-	-	ko00000	2.A.22.4,2.A.22.5	-	-	SNF
NFNHFNFO_04265	33035.JPJF01000051_gene807	3.77e-220	607.0	COG0524@1|root,COG0524@2|Bacteria,1TTAV@1239|Firmicutes,24DX3@186801|Clostridia	186801|Clostridia	G	Kinase, PfkB family	-	-	-	-	-	-	-	-	-	-	-	-	PfkB
NFNHFNFO_04266	33035.JPJF01000051_gene808	0.0	872.0	COG1486@1|root,COG1486@2|Bacteria,1TQ9I@1239|Firmicutes,24995@186801|Clostridia	186801|Clostridia	G	family 4	-	-	3.2.1.86	ko:K01222	ko00010,ko00500,map00010,map00500	-	R00839,R05133,R05134	RC00049,RC00171,RC00714	ko00000,ko00001,ko01000	-	GT4	-	Glyco_hydro_4,Glyco_hydro_4C
NFNHFNFO_04267	33035.JPJF01000051_gene809	0.0	926.0	COG0695@1|root,COG3681@1|root,COG0695@2|Bacteria,COG3681@2|Bacteria,1TQF5@1239|Firmicutes,2488Q@186801|Clostridia,3XYV4@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	SDH_alpha
NFNHFNFO_04268	33035.JPJF01000051_gene810	3.9e-269	739.0	COG1473@1|root,COG1473@2|Bacteria,1TPD7@1239|Firmicutes,248AH@186801|Clostridia,3Y0FD@572511|Blautia	186801|Clostridia	E	Peptidase dimerisation domain	-	-	-	ko:K01436	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	M20_dimer,Peptidase_M20
NFNHFNFO_04269	33035.JPJF01000051_gene811	1.95e-149	421.0	COG2120@1|root,COG2120@2|Bacteria,1TV10@1239|Firmicutes,24J1S@186801|Clostridia	186801|Clostridia	S	PFAM LmbE family protein	-	-	-	ko:K01463	-	-	-	-	ko00000,ko01000	-	-	-	PIG-L
NFNHFNFO_04270	33035.JPJF01000051_gene812	4.43e-185	515.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04271	33035.JPJF01000051_gene813	1.07e-188	527.0	COG1175@1|root,COG1175@2|Bacteria,1TREE@1239|Firmicutes,24B75@186801|Clostridia	186801|Clostridia	P	Abc transporter, permease protein	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04272	33035.JPJF01000051_gene814	2.95e-297	812.0	COG1653@1|root,COG1653@2|Bacteria,1TRIH@1239|Firmicutes,248X0@186801|Clostridia	186801|Clostridia	G	solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_04273	33035.JPJF01000051_gene815	1.55e-214	594.0	COG1609@1|root,COG1609@2|Bacteria,1TSDP@1239|Firmicutes,24E9C@186801|Clostridia	186801|Clostridia	K	Periplasmic binding protein-like domain	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_04274	33035.JPJF01000051_gene816	5.62e-252	691.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,3XYNV@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_04275	33035.JPJF01000051_gene817	2.76e-292	796.0	COG0138@1|root,COG0138@2|Bacteria,1TPQ5@1239|Firmicutes,24AB8@186801|Clostridia,3XYNE@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	purH	-	2.1.2.3,3.5.4.10	ko:K00602	ko00230,ko00670,ko01100,ko01110,ko01130,ko01523,map00230,map00670,map01100,map01110,map01130,map01523	M00048	R01127,R04560	RC00026,RC00263,RC00456	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	AICARFT_IMPCHas
NFNHFNFO_04276	33035.JPJF01000051_gene818	1.34e-166	466.0	COG3363@1|root,COG3363@2|Bacteria,1TRA7@1239|Firmicutes,249ZW@186801|Clostridia,3XZ1G@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	IMP_cyclohyd
NFNHFNFO_04277	33035.JPJF01000051_gene821	1.97e-275	754.0	COG1092@1|root,COG1092@2|Bacteria,1TRAJ@1239|Firmicutes,247TI@186801|Clostridia,3XZRE@572511|Blautia	186801|Clostridia	J	Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase	rlmI	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM,PUA
NFNHFNFO_04278	33035.JPJF01000051_gene822	2.33e-184	517.0	COG1476@1|root,COG1476@2|Bacteria,1V7I5@1239|Firmicutes,24KRY@186801|Clostridia,3Y0HW@572511|Blautia	186801|Clostridia	K	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_04279	33035.JPJF01000051_gene823	1.97e-120	346.0	COG1451@1|root,COG1451@2|Bacteria,1V6WP@1239|Firmicutes,24JGH@186801|Clostridia	186801|Clostridia	E	Psort location Cytoplasmic, score	-	-	-	ko:K07043	-	-	-	-	ko00000	-	-	-	DUF45
NFNHFNFO_04280	537007.BLAHAN_06778	1.57e-169	478.0	COG0024@1|root,COG0024@2|Bacteria,1TQC1@1239|Firmicutes,248I8@186801|Clostridia,3XZRD@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	map	-	3.4.11.18	ko:K01265	-	-	-	-	ko00000,ko01000,ko01002	-	-	-	Peptidase_M24,SEC-C
NFNHFNFO_04281	33035.JPJF01000114_gene2277	2.16e-136	388.0	COG2755@1|root,COG2755@2|Bacteria,1V49F@1239|Firmicutes,24D1K@186801|Clostridia,3Y0I8@572511|Blautia	186801|Clostridia	E	GDSL-like Lipase/Acylhydrolase family	-	-	-	-	-	-	-	-	-	-	-	-	Lipase_GDSL_2
NFNHFNFO_04282	33035.JPJF01000114_gene2278	6.21e-111	320.0	COG1670@1|root,COG1670@2|Bacteria,1V4IY@1239|Firmicutes,24FWK@186801|Clostridia	186801|Clostridia	J	guanosine monophosphate synthetase GuaA K01951	guaA3	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3,DUF3795
NFNHFNFO_04283	33035.JPJF01000114_gene2279	1.52e-101	295.0	COG0454@1|root,COG0456@2|Bacteria,1V6Z8@1239|Firmicutes,24JT6@186801|Clostridia,3Y06X@572511|Blautia	186801|Clostridia	K	COG COG0454 Histone acetyltransferase HPA2 and related acetyltransferases	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_04284	33035.JPJF01000114_gene2280	4.58e-146	410.0	COG1592@1|root,COG1592@2|Bacteria,1V05U@1239|Firmicutes,24BTY@186801|Clostridia,3Y015@572511|Blautia	186801|Clostridia	C	Rubrerythrin	rbr1	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
NFNHFNFO_04285	33035.JPJF01000114_gene2281	1.77e-134	383.0	COG1102@1|root,COG1102@2|Bacteria,1V79E@1239|Firmicutes,24GMW@186801|Clostridia,3XZZJ@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NFNHFNFO_04286	33035.JPJF01000114_gene2282	1.27e-312	856.0	COG0665@1|root,COG0723@1|root,COG0665@2|Bacteria,COG0723@2|Bacteria,1TR1R@1239|Firmicutes,24A67@186801|Clostridia,3XZJX@572511|Blautia	186801|Clostridia	CE	Rieske [2Fe-2S] domain	-	-	-	-	-	-	-	-	-	-	-	-	DAO,Rieske
NFNHFNFO_04287	33035.JPJF01000114_gene2283	1.31e-99	289.0	COG2258@1|root,COG2258@2|Bacteria,1V6DS@1239|Firmicutes,24HBA@186801|Clostridia,3XZZW@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	MOSC,MoCF_biosynth
NFNHFNFO_04288	33035.JPJF01000114_gene2284	5.18e-225	621.0	COG2896@1|root,COG2896@2|Bacteria,1TP89@1239|Firmicutes,247PP@186801|Clostridia,3XZDJ@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	moaA	-	4.1.99.22	ko:K03639	ko00790,ko01100,ko04122,map00790,map01100,map04122	-	R09394	RC03420	ko00000,ko00001,ko01000	-	-	-	Fer4_12,Fer4_14,Mob_synth_C,Radical_SAM
NFNHFNFO_04289	33035.JPJF01000114_gene2285	1.21e-109	317.0	COG1592@1|root,COG1592@2|Bacteria,1V1FF@1239|Firmicutes,248V2@186801|Clostridia,3XZBD@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Rubrerythrin
NFNHFNFO_04290	33035.JPJF01000114_gene2286	5.13e-69	209.0	COG2315@1|root,COG2315@2|Bacteria,1VVT6@1239|Firmicutes,25EAU@186801|Clostridia,3Y0FV@572511|Blautia	186801|Clostridia	L	YjbR	ogt	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1,YjbR
NFNHFNFO_04291	33035.JPJF01000114_gene2287	0.0	929.0	COG0028@1|root,COG0028@2|Bacteria,1TQE8@1239|Firmicutes,2480U@186801|Clostridia,3XZCN@572511|Blautia	186801|Clostridia	H	COG COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase	ilvB	-	2.2.1.6	ko:K01652	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_M,TPP_enzyme_N
NFNHFNFO_04292	33035.JPJF01000086_gene907	8.19e-108	311.0	COG0440@1|root,COG0440@2|Bacteria,1V3PG@1239|Firmicutes,24A0D@186801|Clostridia,3XZ1J@572511|Blautia	186801|Clostridia	E	COG COG0440 Acetolactate synthase, small (regulatory) subunit	ilvH_1	-	2.2.1.6	ko:K01653	ko00290,ko00650,ko00660,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00650,map00660,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R00006,R00014,R00226,R03050,R04672,R04673,R08648	RC00027,RC00106,RC01192,RC02744,RC02893	ko00000,ko00001,ko00002,ko01000	-	-	-	ACT,ACT_5,ALS_ss_C
NFNHFNFO_04293	33035.JPJF01000086_gene908	0.0	1306.0	COG2199@1|root,COG2203@1|root,COG2199@2|Bacteria,COG2203@2|Bacteria,1U78Z@1239|Firmicutes,24NZ8@186801|Clostridia,3Y14E@572511|Blautia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF,PAS_3
NFNHFNFO_04297	411468.CLOSCI_01915	9.27e-187	526.0	COG0582@1|root,COG0582@2|Bacteria,1V1W1@1239|Firmicutes,24G5V@186801|Clostridia	186801|Clostridia	L	Belongs to the 'phage' integrase family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_integrase
NFNHFNFO_04298	411461.DORFOR_02053	6.66e-145	421.0	COG2946@1|root,COG2946@2|Bacteria,1TST2@1239|Firmicutes	2|Bacteria	L	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07467	-	-	-	-	ko00000	-	-	-	HTH_3,Rep_trans
NFNHFNFO_04299	411470.RUMGNA_03135	1.81e-61	191.0	2CE0F@1|root,33VDC@2|Bacteria,1VUJY@1239|Firmicutes,2509T@186801|Clostridia,3Y1PY@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04300	742733.HMPREF9469_03085	6.97e-110	322.0	COG1396@1|root,COG1396@2|Bacteria,1VM51@1239|Firmicutes,24FE9@186801|Clostridia	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_04301	768704.Desmer_3397	1.75e-62	206.0	2DC01@1|root,2ZC51@2|Bacteria,1V2FW@1239|Firmicutes,24I9M@186801|Clostridia	186801|Clostridia	S	TraX protein	-	-	-	-	-	-	-	-	-	-	-	-	TraX
NFNHFNFO_04303	553973.CLOHYLEM_05166	1.27e-38	133.0	2BWQV@1|root,346D0@2|Bacteria,1VZMB@1239|Firmicutes,24S93@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04304	553973.CLOHYLEM_05165	6.88e-21	84.0	28URH@1|root,2ZGVT@2|Bacteria,1W5TU@1239|Firmicutes,24VG4@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04305	33035.JPJF01000086_gene922	0.0	1457.0	COG0366@1|root,COG0366@2|Bacteria,1TNZ0@1239|Firmicutes,247YM@186801|Clostridia,3XYPB@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 9.98	tvaI	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase,Alpha-amylase_C,Alpha-amylase_N
NFNHFNFO_04306	33035.JPJF01000086_gene923	0.0	1159.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XYI4@572511|Blautia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NFNHFNFO_04307	33035.JPJF01000086_gene924	2.61e-117	336.0	COG0634@1|root,COG0634@2|Bacteria,1V1C9@1239|Firmicutes,24FR4@186801|Clostridia,3XZH4@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 9.98	hpt	-	2.4.2.8	ko:K00760	ko00230,ko00983,ko01100,ko01110,map00230,map00983,map01100,map01110	-	R00190,R01132,R01229,R02142,R08237,R08238,R08245	RC00063,RC00122	ko00000,ko00001,ko01000	-	-	-	Pribosyltran
NFNHFNFO_04308	33035.JPJF01000086_gene925	2e-283	780.0	COG0037@1|root,COG0037@2|Bacteria,1TPXP@1239|Firmicutes,248TY@186801|Clostridia,3XZQI@572511|Blautia	186801|Clostridia	D	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine	tilS	-	6.3.4.19	ko:K04075	-	-	R09597	RC02633,RC02634	ko00000,ko01000,ko03016	-	-	-	ATP_bind_3,TilS,TilS_C
NFNHFNFO_04309	33035.JPJF01000086_gene926	0.0	966.0	COG2208@1|root,COG2208@2|Bacteria,1TQ92@1239|Firmicutes,247XG@186801|Clostridia,3XYWW@572511|Blautia	186801|Clostridia	KT	Psort location Cytoplasmic, score 8.87	spoIIE	-	3.1.3.16	ko:K06382	-	-	-	-	ko00000,ko01000	-	-	-	SpoIIE
NFNHFNFO_04310	33035.JPJF01000086_gene927	4.87e-36	124.0	COG2919@1|root,COG2919@2|Bacteria,1VGPP@1239|Firmicutes,24R6M@186801|Clostridia,3Y0KS@572511|Blautia	186801|Clostridia	D	Septum formation initiator	-	-	-	-	-	-	-	-	-	-	-	-	DivIC
NFNHFNFO_04311	33035.JPJF01000086_gene928	1.92e-99	290.0	2EFTM@1|root,32YR5@2|Bacteria,1VEV2@1239|Firmicutes,25JHW@186801|Clostridia,3Y0V0@572511|Blautia	186801|Clostridia	S	Spore cortex protein YabQ (Spore_YabQ)	-	-	-	-	-	-	-	-	-	-	-	-	Spore_YabQ
NFNHFNFO_04312	33035.JPJF01000086_gene929	5.43e-57	177.0	2E3ZZ@1|root,32YWW@2|Bacteria,1VEIW@1239|Firmicutes,24QNQ@186801|Clostridia,3Y0MV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yabP	-	-	-	-	-	-	-	-	-	-	-	YabP
NFNHFNFO_04313	33035.JPJF01000086_gene930	4.8e-46	148.0	COG1188@1|root,COG1188@2|Bacteria,1VEI5@1239|Firmicutes,24QNF@186801|Clostridia,3Y0D7@572511|Blautia	186801|Clostridia	J	COG COG1188 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog)	hslR	-	-	-	-	-	-	-	-	-	-	-	S4
NFNHFNFO_04314	33035.JPJF01000086_gene931	6.27e-52	164.0	COG0776@1|root,COG0776@2|Bacteria,1V9XQ@1239|Firmicutes,24MM0@186801|Clostridia,3Y0HQ@572511|Blautia	186801|Clostridia	L	Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions	hup	-	-	ko:K03530	-	-	-	-	ko00000,ko03032,ko03036,ko03400	-	-	-	Bac_DNA_binding
NFNHFNFO_04315	33035.JPJF01000086_gene932	0.0	1125.0	COG1109@1|root,COG1109@2|Bacteria,1TP2N@1239|Firmicutes,2481Y@186801|Clostridia,3XYJR@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pgcA	-	5.4.2.2,5.4.2.8	ko:K01835,ko:K01840	ko00010,ko00030,ko00051,ko00052,ko00230,ko00500,ko00520,ko00521,ko01100,ko01110,ko01120,ko01130,map00010,map00030,map00051,map00052,map00230,map00500,map00520,map00521,map01100,map01110,map01120,map01130	M00114,M00549	R00959,R01057,R01818,R08639	RC00408	ko00000,ko00001,ko00002,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NFNHFNFO_04316	33035.JPJF01000086_gene933	4.5e-234	644.0	COG2334@1|root,COG2334@2|Bacteria,1TTBS@1239|Firmicutes,2483F@186801|Clostridia,3XYQZ@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	cotS	-	-	ko:K06331,ko:K06337	-	-	-	-	ko00000	-	-	-	APH,Choline_kinase
NFNHFNFO_04317	33035.JPJF01000022_gene3289	2.06e-284	781.0	COG0617@1|root,COG0617@2|Bacteria,1TQ2A@1239|Firmicutes,247XC@186801|Clostridia,3XZRW@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	cca	-	2.7.7.19,2.7.7.72	ko:K00970,ko:K00974	ko03013,ko03018,map03013,map03018	-	R09382,R09383,R09384,R09386	RC00078	ko00000,ko00001,ko01000,ko03016,ko03019	-	-	-	HD,PolyA_pol,PolyA_pol_RNAbd,tRNA_NucTran2_2
NFNHFNFO_04318	33035.JPJF01000022_gene3290	0.0	959.0	COG0441@1|root,COG0441@2|Bacteria,1UHT4@1239|Firmicutes,25E98@186801|Clostridia,3XZ9B@572511|Blautia	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro)	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,ProRS-C_1,tRNA-synt_2b
NFNHFNFO_04319	33035.JPJF01000022_gene3291	1.43e-115	330.0	COG2131@1|root,COG2131@2|Bacteria,1V3PU@1239|Firmicutes,24HF0@186801|Clostridia,3XZHH@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	comEB	-	3.5.4.12	ko:K01493	ko00240,ko01100,map00240,map01100	M00429	R01663	RC00074	ko00000,ko00001,ko00002,ko01000,ko02044	-	-	-	dCMP_cyt_deam_1
NFNHFNFO_04320	33035.JPJF01000022_gene3292	9.62e-143	403.0	COG0035@1|root,COG0035@2|Bacteria,1TPMT@1239|Firmicutes,248FV@186801|Clostridia,3XZJ9@572511|Blautia	186801|Clostridia	F	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate	upp	-	2.4.2.9	ko:K00761	ko00240,ko01100,map00240,map01100	-	R00966	RC00063	ko00000,ko00001,ko01000	-	-	-	UPRTase
NFNHFNFO_04321	33035.JPJF01000022_gene3293	1.75e-100	291.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3XZXS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	rpiB	-	5.3.1.6	ko:K01808	ko00030,ko00051,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00051,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01056,R09030	RC00376,RC00434	ko00000,ko00001,ko00002,ko01000	-	-	-	LacAB_rpiB
NFNHFNFO_04322	33035.JPJF01000022_gene3294	3.5e-230	636.0	COG0009@1|root,COG0009@2|Bacteria,1TP1I@1239|Firmicutes,248HS@186801|Clostridia,3XZ73@572511|Blautia	186801|Clostridia	H	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine	sua	-	2.7.7.87	ko:K07566	-	-	R10463	RC00745	ko00000,ko01000,ko03009,ko03016	-	-	-	SUA5,Sua5_yciO_yrdC
NFNHFNFO_04323	33035.JPJF01000022_gene3295	6e-151	426.0	COG0860@1|root,COG0860@2|Bacteria,1TQ74@1239|Firmicutes,24FT2@186801|Clostridia,3XZTY@572511|Blautia	186801|Clostridia	M	N-acetylmuramoyl-L-alanine amidase	cwlD	-	3.5.1.28	ko:K01448	ko01503,map01503	M00727	R04112	RC00064,RC00141	ko00000,ko00001,ko00002,ko01000,ko01011,ko03036	-	-	-	Amidase_3
NFNHFNFO_04324	33035.JPJF01000022_gene3296	0.0	1324.0	COG5001@1|root,COG5001@2|Bacteria,1TP8V@1239|Firmicutes,247PX@186801|Clostridia,3Y1FR@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3
NFNHFNFO_04325	33035.JPJF01000022_gene3297	4.75e-123	357.0	2D9P4@1|root,32TTM@2|Bacteria,1VCY3@1239|Firmicutes,24NB7@186801|Clostridia,3Y08U@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04326	33035.JPJF01000022_gene3298	0.0	1021.0	COG3858@1|root,COG3858@2|Bacteria,1TQK2@1239|Firmicutes,247YF@186801|Clostridia,3XZGJ@572511|Blautia	186801|Clostridia	S	Glyco_18	ydhD	-	-	-	-	-	-	-	-	-	-	-	CW_binding_2,Cu_amine_oxidN1,Glyco_hydro_18,SH3_3
NFNHFNFO_04327	33035.JPJF01000022_gene3299	7.79e-41	137.0	2EHIK@1|root,32JCB@2|Bacteria,1UQK2@1239|Firmicutes,258C2@186801|Clostridia,3Y0SM@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04328	33035.JPJF01000022_gene3300	1.88e-167	469.0	COG4862@1|root,COG4862@2|Bacteria,1UZ7D@1239|Firmicutes,24BWV@186801|Clostridia,3XZPB@572511|Blautia	186801|Clostridia	NOT	COG COG4862 Negative regulator of genetic competence, sporulation and motility	mecB	-	-	ko:K16511	-	-	-	-	ko00000	-	-	-	MecA
NFNHFNFO_04329	33035.JPJF01000022_gene3301	9.99e-40	131.0	COG2846@1|root,COG2846@2|Bacteria,1VET8@1239|Firmicutes,24QPY@186801|Clostridia,3Y0MQ@572511|Blautia	186801|Clostridia	D	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	DUF1858
NFNHFNFO_04330	33035.JPJF01000022_gene3302	6.88e-18	75.9	COG1148@1|root,COG1148@2|Bacteria,1UI0M@1239|Firmicutes,25E99@186801|Clostridia,3Y0Q0@572511|Blautia	186801|Clostridia	C	4Fe-4S binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Fer4
NFNHFNFO_04331	33035.JPJF01000022_gene3303	3.86e-100	298.0	COG0789@1|root,COG0789@2|Bacteria,1V4F1@1239|Firmicutes,24NFY@186801|Clostridia,3Y0KV@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1
NFNHFNFO_04332	33035.JPJF01000022_gene3304	2.55e-172	482.0	COG1028@1|root,COG1028@2|Bacteria,1TSBE@1239|Firmicutes,24BPX@186801|Clostridia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NFNHFNFO_04333	33035.JPJF01000022_gene3307	1.23e-247	684.0	COG1454@1|root,COG1454@2|Bacteria,1UY3E@1239|Firmicutes,25E9A@186801|Clostridia,3Y1KX@572511|Blautia	186801|Clostridia	C	Iron-containing alcohol dehydrogenase	-	-	1.1.1.1	ko:K13954	ko00010,ko00071,ko00350,ko00625,ko00626,ko01100,ko01110,ko01120,ko01130,ko01220,map00010,map00071,map00350,map00625,map00626,map01100,map01110,map01120,map01130,map01220	-	R00623,R00754,R04880,R05233,R05234,R06917,R06927	RC00050,RC00088,RC00099,RC00116,RC00649	ko00000,ko00001,ko01000	-	-	-	Fe-ADH
NFNHFNFO_04334	33035.JPJF01000022_gene3308	0.0	1007.0	COG3669@1|root,COG3669@2|Bacteria,1U9XH@1239|Firmicutes,24DER@186801|Clostridia	186801|Clostridia	G	Alpha-L-fucosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha_L_fucos
NFNHFNFO_04335	33035.JPJF01000022_gene3309	6.12e-129	371.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3XZXP@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04336	33035.JPJF01000022_gene3310	5.58e-184	513.0	COG1175@1|root,COG1175@2|Bacteria,1TRP6@1239|Firmicutes,24YGY@186801|Clostridia,3Y047@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04337	33035.JPJF01000022_gene3311	5.47e-302	828.0	COG1653@1|root,COG1653@2|Bacteria,1UZ95@1239|Firmicutes,24CZU@186801|Clostridia,3Y01G@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_04338	33035.JPJF01000022_gene3312	2.37e-268	736.0	COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,24AE3@186801|Clostridia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
NFNHFNFO_04339	33035.JPJF01000022_gene3313	3.19e-250	691.0	COG1940@1|root,COG1940@2|Bacteria,1TPKW@1239|Firmicutes,248U9@186801|Clostridia,3XYHF@572511|Blautia	186801|Clostridia	GK	Psort location Cytoplasmic, score	-	-	2.7.1.2	ko:K00845	ko00010,ko00052,ko00500,ko00520,ko00521,ko00524,ko01100,ko01110,ko01120,ko01130,ko01200,map00010,map00052,map00500,map00520,map00521,map00524,map01100,map01110,map01120,map01130,map01200	M00001,M00549	R00299,R01600,R01786	RC00002,RC00017	ko00000,ko00001,ko00002,ko01000	-	-	-	ROK
NFNHFNFO_04340	33035.JPJF01000022_gene3314	1.49e-93	273.0	COG3238@1|root,COG3238@2|Bacteria,1V6J0@1239|Firmicutes,24JM9@186801|Clostridia,3Y03G@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K09936	ko02024,map02024	-	-	-	ko00000,ko00001,ko02000	2.A.7.21	-	-	DMT_YdcZ
NFNHFNFO_04341	33035.JPJF01000022_gene3315	4.14e-279	764.0	COG4992@1|root,COG4992@2|Bacteria,1TP9S@1239|Firmicutes,248C9@186801|Clostridia,3XYZW@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argD	-	2.6.1.11,2.6.1.17	ko:K00821	ko00220,ko00300,ko01100,ko01110,ko01120,ko01130,ko01210,ko01230,map00220,map00300,map01100,map01110,map01120,map01130,map01210,map01230	M00016,M00028,M00845	R02283,R04475	RC00006,RC00062	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_3
NFNHFNFO_04342	33035.JPJF01000022_gene3316	1.85e-209	579.0	COG0548@1|root,COG0548@2|Bacteria,1TP0N@1239|Firmicutes,2486J@186801|Clostridia,3XZI8@572511|Blautia	186801|Clostridia	E	Belongs to the acetylglutamate kinase family. ArgB subfamily	argB	-	2.7.2.8	ko:K00930	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R02649	RC00002,RC00043	ko00000,ko00001,ko00002,ko01000	-	-	-	AA_kinase
NFNHFNFO_04343	33035.JPJF01000022_gene3317	2.47e-273	750.0	COG1364@1|root,COG1364@2|Bacteria,1TPBP@1239|Firmicutes,2497Q@186801|Clostridia,3XZ0G@572511|Blautia	186801|Clostridia	E	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate	argJ	-	2.3.1.1,2.3.1.35	ko:K00620	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028	R00259,R02282	RC00004,RC00064	ko00000,ko00001,ko00002,ko01000	-	-	-	ArgJ
NFNHFNFO_04344	33035.JPJF01000022_gene3318	5.8e-248	681.0	COG0002@1|root,COG0002@2|Bacteria,1TPVI@1239|Firmicutes,247R3@186801|Clostridia,3XZMQ@572511|Blautia	186801|Clostridia	E	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde	argC	-	1.2.1.38	ko:K00145	ko00220,ko01100,ko01110,ko01130,ko01210,ko01230,map00220,map01100,map01110,map01130,map01210,map01230	M00028,M00845	R03443	RC00684	ko00000,ko00001,ko00002,ko01000	-	-	-	Semialdhyde_dh,Semialdhyde_dhC
NFNHFNFO_04345	33035.JPJF01000022_gene3319	1.35e-303	827.0	COG0137@1|root,COG0137@2|Bacteria,1TP3X@1239|Firmicutes,247MF@186801|Clostridia,3XYUF@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	argG	-	6.3.4.5	ko:K01940	ko00220,ko00250,ko01100,ko01110,ko01130,ko01230,ko05418,map00220,map00250,map01100,map01110,map01130,map01230,map05418	M00029,M00844,M00845	R01954	RC00380,RC00629	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	Arginosuc_synth
NFNHFNFO_04346	658086.HMPREF0994_01799	3.29e-101	303.0	COG5464@1|root,COG5464@2|Bacteria,1TYDT@1239|Firmicutes,24EGK@186801|Clostridia,27TQ3@186928|unclassified Lachnospiraceae	186801|Clostridia	S	PD-(D/E)XK nuclease family transposase	-	-	-	-	-	-	-	-	-	-	-	-	DUF4351,HTH_7,PDDEXK_2
NFNHFNFO_04347	658086.HMPREF0994_06178	2.07e-36	137.0	COG3290@1|root,COG3290@2|Bacteria,1VC62@1239|Firmicutes,25FKE@186801|Clostridia,27U05@186928|unclassified Lachnospiraceae	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NFNHFNFO_04348	33035.JPJF01000022_gene3320	0.0	1555.0	COG0695@1|root,COG1328@1|root,COG0695@2|Bacteria,COG1328@2|Bacteria,1TR9K@1239|Firmicutes,247WF@186801|Clostridia,3XZ7A@572511|Blautia	186801|Clostridia	FO	Psort location Cytoplasmic, score 8.87	nrdD	-	1.1.98.6	ko:K21636	ko00230,ko00240,ko01100,map00230,map00240,map01100	M00053	R11633,R11634,R11635,R11636	RC00613	ko00000,ko00001,ko00002,ko01000	-	-	-	ATP-cone,Glutaredoxin,NRDD
NFNHFNFO_04349	33035.JPJF01000022_gene3321	3.09e-270	743.0	COG2262@1|root,COG2262@2|Bacteria,1TNZB@1239|Firmicutes,248IU@186801|Clostridia,3XZ8M@572511|Blautia	186801|Clostridia	S	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis	hflX	-	-	ko:K03665	-	-	-	-	ko00000,ko03009	-	-	-	GTP-bdg_M,GTP-bdg_N,MMR_HSR1
NFNHFNFO_04352	33035.JPJF01000022_gene3323	1.84e-182	511.0	COG1131@1|root,COG1131@2|Bacteria,1TPZR@1239|Firmicutes,247NW@186801|Clostridia,3Y11Y@572511|Blautia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_04353	33035.JPJF01000022_gene3324	2.92e-76	228.0	COG1725@1|root,COG1725@2|Bacteria,1V9ZC@1239|Firmicutes,24NTW@186801|Clostridia,3Y08N@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K07979	-	-	-	-	ko00000,ko03000	-	-	-	GntR
NFNHFNFO_04354	33035.JPJF01000022_gene3325	0.0	1212.0	COG3387@1|root,COG3387@2|Bacteria,1UI0N@1239|Firmicutes,25DI4@186801|Clostridia	186801|Clostridia	G	Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain	-	-	-	-	-	-	-	-	-	-	-	-	Bac_rhamnosid,Bac_rhamnosid6H,Bac_rhamnosid_N
NFNHFNFO_04355	33035.JPJF01000028_gene2749	0.0	1000.0	COG0577@1|root,COG0577@2|Bacteria,1TR2D@1239|Firmicutes,2481J@186801|Clostridia,3Y0AT@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX
NFNHFNFO_04356	33035.JPJF01000028_gene2750	1.79e-172	483.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,3XZDV@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_04357	33035.JPJF01000028_gene2751	1.69e-204	570.0	COG0642@1|root,COG2205@2|Bacteria,1TSIC@1239|Firmicutes,248W8@186801|Clostridia,3Y000@572511|Blautia	186801|Clostridia	T	Histidine kinase-like ATPases	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c
NFNHFNFO_04358	33035.JPJF01000028_gene2752	1.36e-138	394.0	COG0745@1|root,COG0745@2|Bacteria,1TR32@1239|Firmicutes,249TG@186801|Clostridia,3Y06R@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_04359	33035.JPJF01000028_gene2755	2.21e-220	610.0	COG0457@1|root,COG0457@2|Bacteria,1V4J9@1239|Firmicutes,24VUT@186801|Clostridia,3XYS1@572511|Blautia	186801|Clostridia	S	Tetratricopeptide repeat	-	-	-	-	-	-	-	-	-	-	-	-	TPR_16,TPR_19,TPR_2,TPR_8
NFNHFNFO_04360	33035.JPJF01000028_gene2756	0.0	876.0	COG1109@1|root,COG1109@2|Bacteria,1TP1X@1239|Firmicutes,2499P@186801|Clostridia,3XYSV@572511|Blautia	186801|Clostridia	G	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate	glmM	-	5.4.2.10	ko:K03431	ko00520,ko01100,ko01130,map00520,map01100,map01130	-	R02060	RC00408	ko00000,ko00001,ko01000	-	-	-	PGM_PMM_I,PGM_PMM_II,PGM_PMM_III,PGM_PMM_IV
NFNHFNFO_04361	33035.JPJF01000028_gene2757	2.92e-205	569.0	COG1209@1|root,COG1209@2|Bacteria,1TPR2@1239|Firmicutes,2490F@186801|Clostridia,3XYIA@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	NTP_transferase
NFNHFNFO_04362	33035.JPJF01000028_gene2764	3.36e-248	682.0	COG0216@1|root,COG0216@2|Bacteria,1TQ7V@1239|Firmicutes,248CN@186801|Clostridia,3XYXD@572511|Blautia	186801|Clostridia	J	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA	prfA	-	-	ko:K02835	-	-	-	-	ko00000,ko03012	-	-	-	PCRF,RF-1
NFNHFNFO_04363	33035.JPJF01000028_gene2765	7.09e-177	496.0	COG2890@1|root,COG2890@2|Bacteria,1TSMA@1239|Firmicutes,24838@186801|Clostridia,3XZ9I@572511|Blautia	186801|Clostridia	J	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif	prmC	-	2.1.1.297	ko:K02493	-	-	R10806	RC00003,RC03279	ko00000,ko01000,ko03012	-	-	-	MTS,Methyltransf_31
NFNHFNFO_04364	33035.JPJF01000028_gene2766	6.11e-219	607.0	COG3872@1|root,COG3872@2|Bacteria,1TPBU@1239|Firmicutes,25C8E@186801|Clostridia,3XYUQ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	prmC	-	-	-	-	-	-	-	-	-	-	-	DUF1385,MTS
NFNHFNFO_04365	537007.BLAHAN_06295	3.3e-43	140.0	COG0254@1|root,COG0254@2|Bacteria,1VEGU@1239|Firmicutes,24QNZ@186801|Clostridia,3Y0G4@572511|Blautia	186801|Clostridia	J	Binds the 23S rRNA	rpmE	-	-	ko:K02909	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	Ribosomal_L31
NFNHFNFO_04366	33035.JPJF01000028_gene2767	2.75e-305	838.0	COG1158@1|root,COG1158@2|Bacteria,1TPHZ@1239|Firmicutes,247YK@186801|Clostridia,3XZ4R@572511|Blautia	186801|Clostridia	K	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template	rho	-	-	ko:K03628	ko03018,map03018	-	-	-	ko00000,ko00001,ko03019,ko03021	-	-	-	ATP-synt_ab,Rho_N,Rho_RNA_bind
NFNHFNFO_04367	33035.JPJF01000028_gene2768	4.51e-79	235.0	COG0346@1|root,COG0346@2|Bacteria,1V6K3@1239|Firmicutes,24J94@186801|Clostridia,3Y06G@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	gloA	-	4.4.1.5	ko:K01759	ko00620,map00620	-	R02530	RC00004,RC00740	ko00000,ko00001,ko01000	-	-	-	Glyoxalase
NFNHFNFO_04368	33035.JPJF01000028_gene2769	0.0	905.0	COG1219@1|root,COG1219@2|Bacteria,1TPDI@1239|Firmicutes,24AEG@186801|Clostridia,3XYQ7@572511|Blautia	186801|Clostridia	O	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP	clpX_1	-	-	ko:K03544	ko04112,map04112	-	-	-	ko00000,ko00001,ko03110	-	-	-	AAA_2,ClpB_D2-small,zf-C4_ClpX
NFNHFNFO_04369	33035.JPJF01000028_gene2770	0.0	885.0	COG0265@1|root,COG0265@2|Bacteria,1TRM8@1239|Firmicutes,247M5@186801|Clostridia,3XZRU@572511|Blautia	186801|Clostridia	O	Trypsin	-	-	3.4.21.107	ko:K04771	ko01503,ko02020,map01503,map02020	M00728	-	-	ko00000,ko00001,ko00002,ko01000,ko01002,ko03110	-	-	-	PDZ_2,Trypsin_2
NFNHFNFO_04370	33035.JPJF01000028_gene2771	0.0	1176.0	COG0449@1|root,COG0449@2|Bacteria,1TPGU@1239|Firmicutes,248F8@186801|Clostridia,3XZNF@572511|Blautia	186801|Clostridia	M	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source	glmS	-	2.6.1.16	ko:K00820	ko00250,ko00520,ko01100,ko01130,ko04931,map00250,map00520,map01100,map01130,map04931	-	R00768	RC00010,RC00163,RC02752	ko00000,ko00001,ko01000,ko01002	-	-	-	GATase_6,SIS
NFNHFNFO_04371	33035.JPJF01000028_gene2772	5.75e-213	589.0	COG1216@1|root,COG1216@2|Bacteria,1TSXW@1239|Firmicutes,2499G@186801|Clostridia,3XZN2@572511|Blautia	186801|Clostridia	S	LPS side chain defect rhamnosyl transferase	-	-	-	ko:K12992	ko02025,map02025	-	-	-	ko00000,ko00001,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
NFNHFNFO_04372	33035.JPJF01000028_gene2773	1.24e-250	701.0	COG1316@1|root,COG1316@2|Bacteria,1TR1B@1239|Firmicutes,248RH@186801|Clostridia,3XYM4@572511|Blautia	186801|Clostridia	K	COG COG1316 Transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	LytR_cpsA_psr
NFNHFNFO_04373	33035.JPJF01000028_gene2774	0.0	917.0	COG2148@1|root,COG2148@2|Bacteria,1TP7M@1239|Firmicutes,248WV@186801|Clostridia,3XZDD@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	2.7.8.6	ko:K00996	-	-	-	-	ko00000,ko01000,ko01005	-	-	-	Bac_transf,CoA_binding_3
NFNHFNFO_04374	33035.JPJF01000028_gene2775	3.14e-104	303.0	COG0703@1|root,COG0703@2|Bacteria,1VA6Z@1239|Firmicutes,24MQY@186801|Clostridia,3XZNC@572511|Blautia	186801|Clostridia	H	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	CM_2,SKI
NFNHFNFO_04375	33035.JPJF01000028_gene2776	3.85e-299	819.0	COG1249@1|root,COG1249@2|Bacteria,1TP1W@1239|Firmicutes,249R3@186801|Clostridia,3Y1PW@572511|Blautia	186801|Clostridia	C	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain	merA	-	1.16.1.1	ko:K00520	-	-	-	-	ko00000,ko01000	-	-	-	Pyr_redox_2,Pyr_redox_dim
NFNHFNFO_04376	33035.JPJF01000028_gene2777	1.24e-84	251.0	COG1959@1|root,COG1959@2|Bacteria,1W6XJ@1239|Firmicutes,24SDU@186801|Clostridia,3Y0UG@572511|Blautia	186801|Clostridia	K	Winged helix-turn-helix transcription repressor, HrcA DNA-binding	-	-	-	-	-	-	-	-	-	-	-	-	Rrf2
NFNHFNFO_04377	33035.JPJF01000028_gene2778	2.48e-184	515.0	COG0348@1|root,COG0348@2|Bacteria,1TPHF@1239|Firmicutes,247KH@186801|Clostridia,3XZBQ@572511|Blautia	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_5
NFNHFNFO_04378	33035.JPJF01000028_gene2779	4.94e-19	78.2	2EHC1@1|root,33B3W@2|Bacteria,1VMYX@1239|Firmicutes,24UJJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04379	33035.JPJF01000028_gene2780	1.44e-110	325.0	COG0526@1|root,COG0526@2|Bacteria,1VADU@1239|Firmicutes,25B1J@186801|Clostridia	186801|Clostridia	CO	Redoxin	-	-	-	-	-	-	-	-	-	-	-	-	AhpC-TSA,Redoxin
NFNHFNFO_04380	33035.JPJF01000028_gene2781	2.4e-233	643.0	COG1063@1|root,COG1063@2|Bacteria,1UUV0@1239|Firmicutes,25MAN@186801|Clostridia,3Y1TA@572511|Blautia	186801|Clostridia	E	Alcohol dehydrogenase GroES-like domain	-	-	-	-	-	-	-	-	-	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_04381	33035.JPJF01000028_gene2782	1.23e-216	604.0	COG1940@1|root,COG1940@2|Bacteria,1TRT1@1239|Firmicutes,24A9E@186801|Clostridia,3Y11N@572511|Blautia	186801|Clostridia	GK	ROK family	-	-	-	-	-	-	-	-	-	-	-	-	HTH_24,ROK
NFNHFNFO_04382	33035.JPJF01000028_gene2783	0.0	931.0	COG2199@1|root,COG2199@2|Bacteria,1V8BN@1239|Firmicutes,25B1K@186801|Clostridia,3Y2DV@572511|Blautia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NFNHFNFO_04383	33035.JPJF01000028_gene2784	4.57e-228	631.0	COG3568@1|root,COG3568@2|Bacteria,1U5BI@1239|Firmicutes,24A34@186801|Clostridia,3Y02W@572511|Blautia	186801|Clostridia	S	Endonuclease exonuclease phosphatase family protein	-	-	-	-	-	-	-	-	-	-	-	-	Exo_endo_phos
NFNHFNFO_04385	457421.CBFG_01074	7.07e-180	519.0	COG2186@1|root,COG2186@2|Bacteria,1U60C@1239|Firmicutes,25FSW@186801|Clostridia	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
NFNHFNFO_04386	445971.ANASTE_00980	6.73e-101	320.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia,25V53@186806|Eubacteriaceae	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,Hpt,PAS_3,PAS_9,Response_reg
NFNHFNFO_04387	411490.ANACAC_01642	6.3e-273	773.0	COG0642@1|root,COG0745@1|root,COG0784@1|root,COG0745@2|Bacteria,COG0784@2|Bacteria,COG2205@2|Bacteria,1TQMV@1239|Firmicutes,247SE@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA,PAS_3,PAS_9,Response_reg
NFNHFNFO_04388	33035.JPJF01000028_gene2786	6.04e-11	63.5	COG1275@1|root,COG1275@2|Bacteria,1UZAC@1239|Firmicutes,25DYX@186801|Clostridia	186801|Clostridia	P	Voltage-dependent anion channel	-	-	-	ko:K11041	ko05150,map05150	-	-	-	ko00000,ko00001,ko02042	2.A.16	-	-	SLAC1
NFNHFNFO_04389	33035.JPJF01000028_gene2790	1.01e-135	387.0	COG0664@1|root,COG0664@2|Bacteria,1V39R@1239|Firmicutes,24C2I@186801|Clostridia,3XZTI@572511|Blautia	186801|Clostridia	T	Cyclic nucleotide-monophosphate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
NFNHFNFO_04391	180332.JTGN01000005_gene3013	3.14e-245	683.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_04392	742723.HMPREF9477_01551	2.94e-263	723.0	COG3547@1|root,COG3547@2|Bacteria,1TQ5G@1239|Firmicutes,247ME@186801|Clostridia,27IGQ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Transposase IS116/IS110/IS902 family	-	-	-	-	-	-	-	-	-	-	-	-	DEDD_Tnp_IS110,Transposase_20
NFNHFNFO_04394	1121115.AXVN01000044_gene2040	3.12e-176	492.0	COG1484@1|root,COG1484@2|Bacteria,1TQBX@1239|Firmicutes,249T2@186801|Clostridia,3Y0X9@572511|Blautia	186801|Clostridia	L	IstB-like ATP binding N-terminal	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
NFNHFNFO_04395	1469948.JPNB01000002_gene3078	7.31e-13	63.2	2DRCB@1|root,33B75@2|Bacteria,1VPQM@1239|Firmicutes,24VSP@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04399	1280698.AUJS01000003_gene2655	7.81e-42	137.0	2CCB2@1|root,32S7G@2|Bacteria,1VABI@1239|Firmicutes,24MZT@186801|Clostridia,27X06@189330|Dorea	186801|Clostridia	L	Excisionase from transposon Tn916	-	-	-	-	-	-	-	-	-	-	-	-	Tn916-Xis
NFNHFNFO_04400	1121115.AXVN01000044_gene2041	2.04e-102	310.0	COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,24B59@186801|Clostridia,3Y18C@572511|Blautia	186801|Clostridia	L	Integrase core domain	-	-	-	-	-	-	-	-	-	-	-	-	rve
NFNHFNFO_04401	500632.CLONEX_04177	4.92e-90	271.0	COG3328@1|root,COG3328@2|Bacteria,1TP4C@1239|Firmicutes,248UI@186801|Clostridia	186801|Clostridia	L	PFAM transposase, mutator	-	-	-	-	-	-	-	-	-	-	-	-	Transposase_mut
NFNHFNFO_04402	33035.JPJF01000017_gene3808	1.62e-310	847.0	COG0174@1|root,COG0174@2|Bacteria,1TNZA@1239|Firmicutes,2489S@186801|Clostridia,3XYYT@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 9.98	glnA	-	6.3.1.2	ko:K01915	ko00220,ko00250,ko00630,ko00910,ko01100,ko01120,ko01230,ko02020,ko04217,ko04724,ko04727,map00220,map00250,map00630,map00910,map01100,map01120,map01230,map02020,map04217,map04724,map04727	-	R00253	RC00010,RC02798	ko00000,ko00001,ko01000,ko04147	-	-	-	Gln-synt_C,Gln-synt_N
NFNHFNFO_04403	33035.JPJF01000017_gene3807	2e-110	319.0	COG3707@1|root,COG3707@2|Bacteria,1V2S1@1239|Firmicutes,24EWG@186801|Clostridia,3Y020@572511|Blautia	186801|Clostridia	K	ANTAR	-	-	-	ko:K22010	-	M00839	-	-	ko00000,ko00002,ko02022	-	-	-	ANTAR
NFNHFNFO_04404	33035.JPJF01000017_gene3806	3.56e-301	820.0	COG0436@1|root,COG0436@2|Bacteria,1TQD6@1239|Firmicutes,24969@186801|Clostridia,3XYT4@572511|Blautia	186801|Clostridia	H	Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate	dapL	-	2.6.1.83	ko:K10206	ko00300,ko01100,ko01110,ko01130,ko01230,map00300,map01100,map01110,map01130,map01230	M00527	R07613	RC00006,RC01847	ko00000,ko00001,ko00002,ko01000,ko01007	-	-	-	Aminotran_1_2
NFNHFNFO_04405	33035.JPJF01000017_gene3805	2.4e-296	811.0	COG0017@1|root,COG0017@2|Bacteria,1TP38@1239|Firmicutes,248XN@186801|Clostridia,3XZ7F@572511|Blautia	186801|Clostridia	J	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)	aspS	-	6.1.1.12,6.1.1.23	ko:K01876,ko:K09759	ko00970,map00970	M00359,M00360	R03647,R05577	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016,ko03029	-	-	-	tRNA-synt_2,tRNA_anti-codon
NFNHFNFO_04406	33035.JPJF01000017_gene3804	5.09e-43	142.0	COG0721@1|root,COG0721@2|Bacteria,1VEK3@1239|Firmicutes,24RIE@186801|Clostridia,3Y0HE@572511|Blautia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatC	-	6.3.5.6,6.3.5.7	ko:K02435	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Glu-tRNAGln
NFNHFNFO_04407	33035.JPJF01000017_gene3803	0.0	876.0	COG0154@1|root,COG0154@2|Bacteria,1TP0C@1239|Firmicutes,24911@186801|Clostridia,3XZNT@572511|Blautia	186801|Clostridia	H	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln)	gatA	-	6.3.5.6,6.3.5.7	ko:K02433	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	Amidase
NFNHFNFO_04408	33035.JPJF01000017_gene3802	0.0	878.0	COG0064@1|root,COG0064@2|Bacteria,1TPG3@1239|Firmicutes,247MS@186801|Clostridia,3XYZ1@572511|Blautia	186801|Clostridia	J	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)	gatB	-	6.3.5.6,6.3.5.7	ko:K02434	ko00970,ko01100,map00970,map01100	-	R03905,R04212	RC00010	ko00000,ko00001,ko01000,ko03029	-	-	-	GatB_N,GatB_Yqey
NFNHFNFO_04409	33035.JPJF01000017_gene3801	1.7e-121	355.0	COG0568@1|root,COG0568@2|Bacteria,1VJ02@1239|Firmicutes,24RNB@186801|Clostridia,3Y0EP@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	ko:K03086	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2
NFNHFNFO_04410	33035.JPJF01000017_gene3800	1.77e-134	383.0	COG0491@1|root,COG0491@2|Bacteria,1V2P7@1239|Firmicutes,24KQT@186801|Clostridia	186801|Clostridia	S	Metallo-beta-lactamase superfamily	-	-	-	-	-	-	-	-	-	-	-	-	Lactamase_B
NFNHFNFO_04411	33035.JPJF01000017_gene3799	0.0	1108.0	COG0465@1|root,COG0465@2|Bacteria,1TPTV@1239|Firmicutes,247WQ@186801|Clostridia,3XZ55@572511|Blautia	186801|Clostridia	O	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins	ftsH	-	-	ko:K03798	-	M00742	-	-	ko00000,ko00002,ko01000,ko01002,ko03110	-	-	-	AAA,FtsH_ext,Peptidase_M41
NFNHFNFO_04412	33035.JPJF01000017_gene3796	1.39e-295	809.0	COG2233@1|root,COG2233@2|Bacteria,1TNZZ@1239|Firmicutes,25CEM@186801|Clostridia,3XYP4@572511|Blautia	186801|Clostridia	F	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	Xan_ur_permease
NFNHFNFO_04413	33035.JPJF01000017_gene3795	1.25e-237	652.0	COG5018@1|root,COG5018@2|Bacteria,1TQJZ@1239|Firmicutes,24845@186801|Clostridia,3XYID@572511|Blautia	186801|Clostridia	L	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	RNase_T
NFNHFNFO_04414	33035.JPJF01000017_gene3794	0.0	970.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3XZ1E@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NFNHFNFO_04415	33035.JPJF01000017_gene3793	0.0	1112.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,His_kinase
NFNHFNFO_04416	33035.JPJF01000017_gene3792	0.0	883.0	COG1653@1|root,COG1653@2|Bacteria,1TR0C@1239|Firmicutes,248RD@186801|Clostridia	186801|Clostridia	G	solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
NFNHFNFO_04417	33035.JPJF01000017_gene3791	1.11e-208	577.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_04418	33035.JPJF01000017_gene3790	2.45e-184	514.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04419	33035.JPJF01000017_gene3789	0.0	1602.0	COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,247J6@186801|Clostridia	186801|Clostridia	G	hydrolase, family 65, central catalytic	-	-	2.4.1.64	ko:K05342	ko00500,ko01100,map00500,map01100	-	R02727	RC00049	ko00000,ko00001,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m
NFNHFNFO_04420	33035.JPJF01000017_gene3788	4.4e-212	585.0	28H77@1|root,2Z7JH@2|Bacteria,1UZ9E@1239|Firmicutes,247WR@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04421	33035.JPJF01000017_gene3787	0.0	2739.0	COG1196@1|root,COG3250@1|root,COG5434@1|root,COG1196@2|Bacteria,COG3250@2|Bacteria,COG5434@2|Bacteria,1UI0G@1239|Firmicutes,25B1F@186801|Clostridia	186801|Clostridia	M	Parallel beta-helix repeats	-	-	-	-	-	-	-	-	-	-	-	-	Beta_helix,F5_F8_type_C,FIVAR
NFNHFNFO_04422	33035.JPJF01000017_gene3786	0.0	898.0	COG1686@1|root,COG1686@2|Bacteria,1TQ8M@1239|Firmicutes,2480S@186801|Clostridia,3XYN4@572511|Blautia	186801|Clostridia	M	Belongs to the peptidase S11 family	-	-	3.4.16.4	ko:K01286,ko:K07258	ko00550,ko01100,map00550,map01100	-	-	-	ko00000,ko00001,ko01000,ko01002,ko01011	-	-	-	PBP5_C,Peptidase_S11
NFNHFNFO_04423	33035.JPJF01000017_gene3778	5.42e-77	230.0	COG1725@1|root,COG1725@2|Bacteria,1VAC6@1239|Firmicutes,24MVE@186801|Clostridia,3Y0QJ@572511|Blautia	186801|Clostridia	K	helix_turn_helix gluconate operon transcriptional repressor	-	-	-	-	-	-	-	-	-	-	-	-	GntR
NFNHFNFO_04424	33035.JPJF01000017_gene3777	4.35e-205	568.0	COG1131@1|root,COG1131@2|Bacteria,1TS5Y@1239|Firmicutes,24AH1@186801|Clostridia,3Y0DV@572511|Blautia	186801|Clostridia	V	Psort location	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_04426	33035.JPJF01000017_gene3775	3.52e-162	454.0	2DRS1@1|root,33CTC@2|Bacteria,1VPFR@1239|Firmicutes,24X55@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04427	33035.JPJF01000017_gene3774	4.73e-241	662.0	COG1609@1|root,COG1609@2|Bacteria,1UA0B@1239|Firmicutes,24BCB@186801|Clostridia,3Y1DF@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_04428	33035.JPJF01000017_gene3773	0.0	1150.0	COG0366@1|root,COG0366@2|Bacteria,1TR93@1239|Firmicutes,24AB0@186801|Clostridia,3Y2A0@572511|Blautia	186801|Clostridia	G	Alpha amylase, catalytic domain	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-amylase
NFNHFNFO_04429	33035.JPJF01000017_gene3772	2.03e-307	839.0	COG1653@1|root,COG1653@2|Bacteria,1UG52@1239|Firmicutes	1239|Firmicutes	G	ABC transporter	-	-	-	ko:K02027	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_04430	33035.JPJF01000017_gene3771	2.12e-197	548.0	COG1175@1|root,COG1175@2|Bacteria,1TST8@1239|Firmicutes,25C4U@186801|Clostridia,3Y14S@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04431	33035.JPJF01000017_gene3770	8.27e-188	523.0	COG0395@1|root,COG0395@2|Bacteria,1TRXW@1239|Firmicutes,25C4N@186801|Clostridia,3Y17I@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04432	33035.JPJF01000017_gene3769	7.83e-266	726.0	COG1063@1|root,COG1063@2|Bacteria,1TQKZ@1239|Firmicutes,24BU4@186801|Clostridia,3Y10A@572511|Blautia	186801|Clostridia	E	Zinc-binding dehydrogenase	-	-	-	-	-	-	-	-	-	-	-	-	ADH_zinc_N
NFNHFNFO_04433	33035.JPJF01000017_gene3768	2.83e-195	540.0	COG1082@1|root,COG1082@2|Bacteria,1TRXP@1239|Firmicutes,24EWV@186801|Clostridia,3XZTX@572511|Blautia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	5.1.3.30,5.1.3.31	ko:K18910	-	-	R10817,R10818	RC03111,RC03283	ko00000,ko01000	-	-	-	AP_endonuc_2
NFNHFNFO_04434	33035.JPJF01000017_gene3767	3.05e-256	701.0	COG0673@1|root,COG0673@2|Bacteria,1TQ72@1239|Firmicutes,24XW6@186801|Clostridia,3Y133@572511|Blautia	186801|Clostridia	S	Oxidoreductase family, C-terminal alpha/beta domain	-	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_04435	33035.JPJF01000017_gene3766	0.0	1559.0	COG1554@1|root,COG1554@2|Bacteria,1TQMB@1239|Firmicutes,247J6@186801|Clostridia,3Y19N@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolase family 65, C-terminal domain	-	-	2.4.1.230	ko:K04844,ko:K10231	-	-	-	-	ko00000,ko01000	-	GH65	-	Glyco_hydro_65C,Glyco_hydro_65N,Glyco_hydro_65m,HAD_2
NFNHFNFO_04436	33035.JPJF01000017_gene3765	9.08e-145	409.0	COG0637@1|root,COG0637@2|Bacteria,1UY8N@1239|Firmicutes,25B0G@186801|Clostridia,3Y1AF@572511|Blautia	186801|Clostridia	S	HAD-hyrolase-like	pgmB	-	5.4.2.6	ko:K01838	ko00500,map00500	-	R02728,R11310	RC00408	ko00000,ko00001,ko01000	-	-	-	HAD_2
NFNHFNFO_04437	33035.JPJF01000017_gene3763	0.0	2135.0	COG0060@1|root,COG0060@2|Bacteria,1TPS7@1239|Firmicutes,247XX@186801|Clostridia,3XZEW@572511|Blautia	186801|Clostridia	J	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)	ileS	-	6.1.1.5	ko:K01870	ko00970,map00970	M00359,M00360	R03656	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	Anticodon_1,tRNA-synt_1
NFNHFNFO_04438	33035.JPJF01000017_gene3762	0.0	1630.0	COG0058@1|root,COG0058@2|Bacteria,1TQAJ@1239|Firmicutes,248E1@186801|Clostridia,3XZEY@572511|Blautia	186801|Clostridia	G	Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties	glgP	-	2.4.1.1	ko:K00688	ko00500,ko01100,ko01110,ko02026,ko04217,ko04910,ko04922,ko04931,map00500,map01100,map01110,map02026,map04217,map04910,map04922,map04931	-	R02111	-	ko00000,ko00001,ko01000	-	GT35	-	Phosphorylase
NFNHFNFO_04439	742740.HMPREF9474_00405	2.31e-111	330.0	COG0583@1|root,COG0583@2|Bacteria,1TP77@1239|Firmicutes,248CX@186801|Clostridia,22480@1506553|Lachnoclostridium	186801|Clostridia	K	LysR substrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_04440	293826.Amet_0661	8.69e-106	329.0	COG1288@1|root,COG1288@2|Bacteria,1TQJ0@1239|Firmicutes,248UK@186801|Clostridia,36DHD@31979|Clostridiaceae	186801|Clostridia	S	C4-dicarboxylate anaerobic carrier	-	-	-	-	-	-	-	-	-	-	-	-	DcuC
NFNHFNFO_04441	742740.HMPREF9474_01860	6.67e-113	349.0	COG2195@1|root,COG2195@2|Bacteria,1TQBS@1239|Firmicutes,24F7T@186801|Clostridia,223X8@1506553|Lachnoclostridium	186801|Clostridia	E	Peptidase family M20/M25/M40	-	-	-	-	-	-	-	-	-	-	-	-	M20_dimer,Peptidase_M20
NFNHFNFO_04442	411483.FAEPRAA2165_01167	1.09e-88	274.0	COG0679@1|root,COG0679@2|Bacteria,1V24M@1239|Firmicutes,25CB9@186801|Clostridia,3WSBZ@541000|Ruminococcaceae	186801|Clostridia	S	Sodium Bile acid symporter family	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NFNHFNFO_04443	33035.JPJF01000017_gene3761	0.0	1164.0	COG0457@1|root,COG0464@1|root,COG0457@2|Bacteria,COG0464@2|Bacteria,1TY3C@1239|Firmicutes,248IE@186801|Clostridia,3XZJN@572511|Blautia	186801|Clostridia	O	Psort location Cytoplasmic, score 8.87	SpoVK	-	-	-	-	-	-	-	-	-	-	-	TPR_8
NFNHFNFO_04444	33035.JPJF01000017_gene3760	7.29e-195	542.0	COG0030@1|root,COG0030@2|Bacteria,1TP9W@1239|Firmicutes,248RY@186801|Clostridia,3XZGB@572511|Blautia	186801|Clostridia	J	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits	ksgA	-	2.1.1.182	ko:K02528	-	-	R10716	RC00003,RC03257	ko00000,ko01000,ko03009	-	-	-	RrnaAD
NFNHFNFO_04445	33035.JPJF01000017_gene3759	7.97e-147	414.0	COG1418@1|root,COG1418@2|Bacteria,1UI0F@1239|Firmicutes,24GIY@186801|Clostridia,3XZYU@572511|Blautia	186801|Clostridia	S	Metal dependent phosphohydrolases with conserved 'HD' motif.	-	-	-	ko:K09163	-	-	-	-	ko00000	-	-	-	HD
NFNHFNFO_04446	742765.HMPREF9457_02961	4.43e-240	670.0	COG1875@1|root,COG1875@2|Bacteria,1UHTD@1239|Firmicutes,25ED1@186801|Clostridia,27WFV@189330|Dorea	186801|Clostridia	T	ATPase related to phosphate starvation-inducible protein PhoH	phoH	-	-	ko:K07175	-	-	-	-	ko00000	-	-	-	PIN_4,PhoH
NFNHFNFO_04447	33035.JPJF01000017_gene3758	9.33e-177	493.0	COG3842@1|root,COG3842@2|Bacteria,1TP2M@1239|Firmicutes,249SV@186801|Clostridia,3Y1GY@572511|Blautia	186801|Clostridia	E	ATPases associated with a variety of cellular activities	-	-	3.6.3.30	ko:K02010	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.10	-	-	ABC_tran
NFNHFNFO_04448	33035.JPJF01000017_gene3757	0.0	941.0	COG1178@1|root,COG1178@2|Bacteria,1UXJF@1239|Firmicutes,25M9I@186801|Clostridia,3Y14J@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04449	33035.JPJF01000017_gene3756	7.61e-222	613.0	COG1840@1|root,COG1840@2|Bacteria,1TT3Y@1239|Firmicutes,24AJP@186801|Clostridia	186801|Clostridia	P	Bacterial extracellular solute-binding protein	-	-	-	ko:K02012	ko02010,map02010	M00190	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.10	-	-	BPD_transp_1,SBP_bac_6
NFNHFNFO_04450	33035.JPJF01000017_gene3755	4.12e-253	695.0	COG0075@1|root,COG0075@2|Bacteria,1TPS0@1239|Firmicutes,24919@186801|Clostridia,3Y0X5@572511|Blautia	186801|Clostridia	E	Cys/Met metabolism PLP-dependent enzyme	phnW	-	2.6.1.37,3.11.1.1	ko:K03430,ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R00747,R04152	RC00008,RC00062,RC00368	ko00000,ko00001,ko01000,ko01007	-	-	-	Aminotran_5,HAD_2
NFNHFNFO_04451	33035.JPJF01000017_gene3754	2.44e-167	469.0	COG0637@1|root,COG0637@2|Bacteria,1TP1A@1239|Firmicutes,24CZD@186801|Clostridia,3Y14W@572511|Blautia	186801|Clostridia	S	Haloacid dehalogenase-like hydrolase	phnX	-	3.11.1.1	ko:K05306	ko00440,ko01100,ko01120,map00440,map01100,map01120	-	R00747	RC00368	ko00000,ko00001,ko01000	-	-	-	HAD_2
NFNHFNFO_04452	33035.JPJF01000017_gene3753	1.75e-248	686.0	COG2207@1|root,COG2207@2|Bacteria,1V28B@1239|Firmicutes,24GF0@186801|Clostridia,3Y1Q2@572511|Blautia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
NFNHFNFO_04453	33035.JPJF01000017_gene3752	0.0	1181.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,249UZ@186801|Clostridia,3Y1VI@572511|Blautia	186801|Clostridia	G	Glycosyl hydrolases family 2, sugar binding domain	-	-	3.2.1.31	ko:K01195	ko00040,ko00531,ko00860,ko00944,ko00983,ko01100,ko01110,ko04142,map00040,map00531,map00860,map00944,map00983,map01100,map01110,map04142	M00014,M00076,M00077,M00078,M00129	R01478,R04979,R07818,R08127,R08260,R10830	RC00055,RC00171,RC00529,RC00530,RC00714,RC01251	ko00000,ko00001,ko00002,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFNHFNFO_04454	33035.JPJF01000017_gene3751	7.9e-287	790.0	COG2211@1|root,COG2211@2|Bacteria,1TRYR@1239|Firmicutes,25C8G@186801|Clostridia,3XZ0S@572511|Blautia	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_04455	33035.JPJF01000017_gene3750	2.35e-266	731.0	COG1940@1|root,COG1940@2|Bacteria,1TQCE@1239|Firmicutes,24AE3@186801|Clostridia,3Y2BB@572511|Blautia	186801|Clostridia	K	MarR family	xylR	-	-	-	-	-	-	-	-	-	-	-	HTH_24,MarR_2,ROK
NFNHFNFO_04456	33035.JPJF01000017_gene3749	1.08e-167	474.0	COG4086@1|root,COG4086@2|Bacteria,1TR2I@1239|Firmicutes,24C10@186801|Clostridia,3XZRQ@572511|Blautia	186801|Clostridia	S	Protein of unknown function (DUF1002)	-	-	-	-	-	-	-	-	-	-	-	-	DUF1002
NFNHFNFO_04457	33035.JPJF01000017_gene3748	3.03e-149	420.0	COG2357@1|root,COG2357@2|Bacteria,1TSC9@1239|Firmicutes,25CET@186801|Clostridia,3XZH1@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	spoT	-	2.7.6.5	ko:K07816	ko00230,map00230	-	R00429	RC00002,RC00078	ko00000,ko00001,ko01000	-	-	-	RelA_SpoT
NFNHFNFO_04458	33035.JPJF01000017_gene3747	2.77e-224	621.0	COG3641@1|root,COG3641@2|Bacteria,1TS5F@1239|Firmicutes,247P0@186801|Clostridia,3XZ5V@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	ko:K07035	-	-	-	-	ko00000	-	-	-	PTS_EIIC_2
NFNHFNFO_04459	33035.JPJF01000017_gene3746	9.96e-152	428.0	COG0539@1|root,COG0539@2|Bacteria,1UYC5@1239|Firmicutes,24AJ1@186801|Clostridia,3XZE6@572511|Blautia	186801|Clostridia	J	Psort location Cytoplasmic, score 9.98	rpsA	-	-	ko:K02945	ko03010,map03010	M00178	-	-	br01610,ko00000,ko00001,ko00002,ko03011	-	-	-	S1
NFNHFNFO_04461	33035.JPJF01000054_gene1623	0.0	1062.0	COG1227@1|root,COG1227@2|Bacteria,1TPH6@1239|Firmicutes,248RQ@186801|Clostridia,3XYRG@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	ppaC	-	3.6.1.1	ko:K15986	ko00190,map00190	-	-	-	ko00000,ko00001,ko01000	-	-	-	CBS,DHH,DHHA2,DRTGG
NFNHFNFO_04462	33035.JPJF01000054_gene1624	0.0	964.0	COG1501@1|root,COG1501@2|Bacteria,1TSIW@1239|Firmicutes,24DS5@186801|Clostridia	186801|Clostridia	G	Glycosyl hydrolases family 31	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_31
NFNHFNFO_04463	33035.JPJF01000054_gene1625	1.94e-136	386.0	COG1853@1|root,COG1853@2|Bacteria,1V1EA@1239|Firmicutes,24FWS@186801|Clostridia,3XYRI@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Flavin_Reduct
NFNHFNFO_04464	33035.JPJF01000054_gene1626	1.15e-104	303.0	COG0703@1|root,COG0703@2|Bacteria,1V3W6@1239|Firmicutes,24HKA@186801|Clostridia,3Y00E@572511|Blautia	186801|Clostridia	F	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate	aroK	-	2.7.1.71	ko:K00891	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R02412	RC00002,RC00078	ko00000,ko00001,ko00002,ko01000	-	-	-	SKI
NFNHFNFO_04465	33035.JPJF01000054_gene1627	1.84e-298	815.0	COG0766@1|root,COG0766@2|Bacteria,1TPAU@1239|Firmicutes,2488W@186801|Clostridia,3XZ1V@572511|Blautia	186801|Clostridia	M	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine	murA	-	2.5.1.7	ko:K00790	ko00520,ko00550,ko01100,map00520,map00550,map01100	-	R00660	RC00350	ko00000,ko00001,ko01000,ko01011	-	-	-	EPSP_synthase
NFNHFNFO_04466	33035.JPJF01000054_gene1628	6.89e-195	541.0	COG2207@1|root,COG3708@1|root,COG2207@2|Bacteria,COG3708@2|Bacteria,1V5FF@1239|Firmicutes,25B27@186801|Clostridia	186801|Clostridia	K	Bacterial transcription activator, effector binding domain	-	-	-	ko:K13653	-	-	-	-	ko00000,ko03000	-	-	-	Cass2,HTH_18
NFNHFNFO_04467	33035.JPJF01000054_gene1629	3e-91	278.0	COG4886@1|root,COG4886@2|Bacteria,1V44C@1239|Firmicutes,25EA1@186801|Clostridia,3Y28C@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	FMN_bind,LRR_5
NFNHFNFO_04469	33035.JPJF01000054_gene1633	0.0	3224.0	COG2340@1|root,COG2340@2|Bacteria,1V1IM@1239|Firmicutes,24PYX@186801|Clostridia	186801|Clostridia	N	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04470	33035.JPJF01000054_gene1634	0.0	2294.0	COG1657@1|root,COG3064@1|root,COG5492@1|root,COG1657@2|Bacteria,COG3064@2|Bacteria,COG5492@2|Bacteria,1UZVS@1239|Firmicutes,24DV2@186801|Clostridia,3Y094@572511|Blautia	186801|Clostridia	IN	Cysteine-rich secretory protein family	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,DUF4430,Prenyltrans,SLH,SQHop_cyclase_C
NFNHFNFO_04471	33035.JPJF01000054_gene1635	3.26e-252	696.0	COG1657@1|root,COG1657@2|Bacteria,1VBUR@1239|Firmicutes,24F29@186801|Clostridia,3Y0B7@572511|Blautia	186801|Clostridia	I	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
NFNHFNFO_04472	33035.JPJF01000054_gene1636	1.11e-243	670.0	COG0619@1|root,COG0619@2|Bacteria,1TSB5@1239|Firmicutes,24AN7@186801|Clostridia,3XZVA@572511|Blautia	186801|Clostridia	P	Cobalt transport protein	-	-	-	ko:K16785	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	CbiQ
NFNHFNFO_04473	33035.JPJF01000054_gene1637	0.0	1085.0	COG1129@1|root,COG1129@2|Bacteria,1TQRP@1239|Firmicutes,24YCF@186801|Clostridia,3XYUV@572511|Blautia	186801|Clostridia	G	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K16786,ko:K16787	ko02010,map02010	M00582	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.25,3.A.1.28,3.A.1.29,3.A.1.30,3.A.1.31,3.A.1.32,3.A.1.33,3.A.1.35	-	-	ABC_tran,ECF-ribofla_trS,ECF_trnsprt
NFNHFNFO_04474	33035.JPJF01000054_gene1638	3.25e-192	535.0	COG4720@1|root,COG4720@2|Bacteria,1V2DR@1239|Firmicutes,249XR@186801|Clostridia,3XZUX@572511|Blautia	186801|Clostridia	S	ECF-type riboflavin transporter, S component	-	-	-	ko:K16927	-	M00582	-	-	ko00000,ko00002,ko02000	3.A.1.32	-	-	ECF-ribofla_trS,ECF_trnsprt
NFNHFNFO_04475	33035.JPJF01000054_gene1639	9.56e-179	499.0	COG4509@1|root,COG4509@2|Bacteria,1TRWN@1239|Firmicutes,24JWH@186801|Clostridia,3Y2BS@572511|Blautia	186801|Clostridia	S	Sortase family	srtB	-	3.4.22.70	ko:K08600	-	-	-	-	ko00000,ko01000,ko01002,ko01011	-	-	-	Sortase
NFNHFNFO_04476	33035.JPJF01000054_gene1640	2.23e-17	80.1	COG1865@1|root,COG1865@2|Bacteria,1TQHV@1239|Firmicutes,24AA4@186801|Clostridia,3Y0CC@572511|Blautia	186801|Clostridia	S	Adenosylcobinamide amidohydrolase	cbiZ	-	-	-	-	-	-	-	-	-	-	-	CbiZ
NFNHFNFO_04477	33035.JPJF01000054_gene1640	4.31e-19	84.7	COG1865@1|root,COG1865@2|Bacteria,1TQHV@1239|Firmicutes,24AA4@186801|Clostridia,3Y0CC@572511|Blautia	186801|Clostridia	S	Adenosylcobinamide amidohydrolase	cbiZ	-	-	-	-	-	-	-	-	-	-	-	CbiZ
NFNHFNFO_04478	33035.JPJF01000054_gene1641	2.38e-135	383.0	COG5423@1|root,COG5423@2|Bacteria,1VBHK@1239|Firmicutes,24XGW@186801|Clostridia,3Y0MP@572511|Blautia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NFNHFNFO_04479	397288.C806_03421	0.0	980.0	COG2273@1|root,COG5492@1|root,COG2273@2|Bacteria,COG5492@2|Bacteria,1TR5U@1239|Firmicutes,248GW@186801|Clostridia,27INE@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Glycosyl hydrolases family 16	-	-	-	-	-	-	-	-	-	-	-	-	Big_2,CBM_4_9,CW_binding_1,Glyco_hydro_16,LRR_5,SLH
NFNHFNFO_04480	658088.HMPREF0987_01444	0.0	1378.0	COG3459@1|root,COG3459@2|Bacteria,1TQY8@1239|Firmicutes,248YP@186801|Clostridia,27I5Y@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Putative carbohydrate binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_36,Glyco_transf_36
NFNHFNFO_04481	658088.HMPREF0987_01442	1.93e-132	380.0	COG2207@1|root,COG2207@2|Bacteria,1UZ5U@1239|Firmicutes,24DJM@186801|Clostridia,27KSF@186928|unclassified Lachnospiraceae	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC
NFNHFNFO_04482	1235799.C818_01560	3.06e-286	787.0	COG1653@1|root,COG1653@2|Bacteria,1TRPJ@1239|Firmicutes,24872@186801|Clostridia,27J2C@186928|unclassified Lachnospiraceae	186801|Clostridia	G	ABC-type sugar transport system periplasmic component	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_04483	1235793.C809_01007	7.4e-180	506.0	COG1175@1|root,COG1175@2|Bacteria,1TS63@1239|Firmicutes,2489M@186801|Clostridia,27JDR@186928|unclassified Lachnospiraceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_04484	1235790.C805_00943	1.53e-167	472.0	COG0395@1|root,COG0395@2|Bacteria,1TS0R@1239|Firmicutes,248UX@186801|Clostridia,25VEU@186806|Eubacteriaceae	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_04485	33035.JPJF01000054_gene1644	2.99e-309	842.0	COG3875@1|root,COG3875@2|Bacteria,1UYM4@1239|Firmicutes,24AR5@186801|Clostridia,3Y1D0@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
NFNHFNFO_04486	33035.JPJF01000054_gene1645	1.25e-239	659.0	COG1063@1|root,COG1063@2|Bacteria,1TS6I@1239|Firmicutes,25B0S@186801|Clostridia,3Y2DN@572511|Blautia	186801|Clostridia	E	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.380	ko:K08322	ko00040,ko01100,map00040,map01100	-	R10848	RC00085	ko00000,ko00001,ko01000	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_04487	33035.JPJF01000054_gene1646	5.13e-154	434.0	COG1802@1|root,COG1802@2|Bacteria,1V3SB@1239|Firmicutes,24EKV@186801|Clostridia	186801|Clostridia	K	transcriptional regulator (GntR	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NFNHFNFO_04488	33035.JPJF01000054_gene1647	1.16e-281	775.0	COG2610@1|root,COG2610@2|Bacteria,1TQ14@1239|Firmicutes,248PQ@186801|Clostridia	186801|Clostridia	EG	Gluconate	-	-	-	ko:K03299	-	-	-	-	ko00000,ko02000	2.A.8	-	-	GntP_permease
NFNHFNFO_04489	33035.JPJF01000054_gene1648	1.12e-151	427.0	COG2186@1|root,COG2186@2|Bacteria,1V5UA@1239|Firmicutes,24BCM@186801|Clostridia,3Y01S@572511|Blautia	186801|Clostridia	K	FCD	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NFNHFNFO_04490	33035.JPJF01000054_gene1649	0.0	1130.0	COG0129@1|root,COG0129@2|Bacteria,1TP1R@1239|Firmicutes,247UC@186801|Clostridia,3Y0XG@572511|Blautia	186801|Clostridia	EG	Dehydratase family	ilvD3	-	4.2.1.9	ko:K01687	ko00290,ko00770,ko01100,ko01110,ko01130,ko01210,ko01230,map00290,map00770,map01100,map01110,map01130,map01210,map01230	M00019,M00570	R01209,R04441,R05070	RC00468,RC01714	ko00000,ko00001,ko00002,ko01000	-	-	-	ILVD_EDD
NFNHFNFO_04491	33035.JPJF01000054_gene1650	5.03e-181	504.0	COG1028@1|root,COG1028@2|Bacteria,1TPZ8@1239|Firmicutes,24903@186801|Clostridia,3Y15M@572511|Blautia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	kduD	-	1.1.1.127,1.1.1.69	ko:K00046,ko:K00065	ko00040,map00040	-	R01542	RC00089	ko00000,ko00001,ko01000	-	-	-	adh_short_C2
NFNHFNFO_04493	33035.JPJF01000054_gene1651	7.17e-267	732.0	COG0192@1|root,COG0192@2|Bacteria,1TPCV@1239|Firmicutes,248QF@186801|Clostridia,3XZ7D@572511|Blautia	186801|Clostridia	H	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme	metK	-	2.5.1.6	ko:K00789	ko00270,ko01100,ko01110,ko01230,map00270,map01100,map01110,map01230	M00034,M00035,M00368,M00609	R00177,R04771	RC00021,RC01211	ko00000,ko00001,ko00002,ko01000	-	-	-	S-AdoMet_synt_C,S-AdoMet_synt_M,S-AdoMet_synt_N
NFNHFNFO_04494	33035.JPJF01000054_gene1652	1.6e-47	152.0	COG1476@1|root,COG1476@2|Bacteria,1VGJ5@1239|Firmicutes,24SZE@186801|Clostridia,3Y1YA@572511|Blautia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NFNHFNFO_04495	33035.JPJF01000054_gene1653	0.0	871.0	COG1672@1|root,COG1672@2|Bacteria,1TR21@1239|Firmicutes,24ADD@186801|Clostridia,3Y0F7@572511|Blautia	186801|Clostridia	S	Archaea bacterial proteins of unknown function	-	-	-	ko:K06921	-	-	-	-	ko00000	-	-	-	ATPase_2,DUF234
NFNHFNFO_04496	33035.JPJF01000054_gene1654	0.0	936.0	COG3850@1|root,COG5002@1|root,COG3850@2|Bacteria,COG5002@2|Bacteria,1TPVJ@1239|Firmicutes,2489X@186801|Clostridia,3XZ9P@572511|Blautia	186801|Clostridia	T	COG COG0642 Signal transduction histidine kinase	yycG_1	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NFNHFNFO_04497	33035.JPJF01000054_gene1655	1.69e-161	452.0	COG0745@1|root,COG0745@2|Bacteria,1TPRU@1239|Firmicutes,24843@186801|Clostridia,3XYGU@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	srrA_2	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_04498	411460.RUMTOR_02680	2.1e-91	278.0	28JN4@1|root,2ZI55@2|Bacteria,1VT72@1239|Firmicutes,24AUX@186801|Clostridia,3Y02C@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04499	33035.JPJF01000027_gene2729	0.0	1399.0	COG1472@1|root,COG1472@2|Bacteria,1TPH5@1239|Firmicutes,247QP@186801|Clostridia,3XZIP@572511|Blautia	186801|Clostridia	G	Fibronectin type III-like domain	-	-	3.2.1.21	ko:K05349	ko00460,ko00500,ko00940,ko01100,ko01110,map00460,map00500,map00940,map01100,map01110	-	R00026,R02558,R02887,R02985,R03527,R04949,R04998,R10035,R10039,R10040	RC00049,RC00059,RC00171,RC00262,RC00397,RC00451,RC00714,RC00746,RC01248	ko00000,ko00001,ko01000	-	GH3	-	Fn3-like,Glyco_hydro_3,Glyco_hydro_3_C
NFNHFNFO_04500	33035.JPJF01000027_gene2728	0.0	1087.0	COG0442@1|root,COG0442@2|Bacteria,1TRBV@1239|Firmicutes,249PY@186801|Clostridia	186801|Clostridia	J	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS	proS	-	6.1.1.15	ko:K01881	ko00970,map00970	M00359,M00360	R03661	RC00055,RC00523	ko00000,ko00001,ko00002,ko01000,ko01007,ko03016	-	-	-	HGTP_anticodon,tRNA-synt_2b,tRNA_edit
NFNHFNFO_04501	33035.JPJF01000027_gene2727	2.21e-274	759.0	COG1982@1|root,COG1982@2|Bacteria,1TNZ9@1239|Firmicutes,247RA@186801|Clostridia,3XYX4@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	speA	-	4.1.1.19	ko:K01585	ko00330,ko01100,map00330,map01100	M00133	R00566	RC00299	ko00000,ko00001,ko00002,ko01000	-	-	-	OKR_DC_1,OKR_DC_1_C
NFNHFNFO_04502	537007.BLAHAN_06050	6.79e-92	273.0	COG0194@1|root,COG0194@2|Bacteria,1V3RZ@1239|Firmicutes,24HKC@186801|Clostridia,3XZXN@572511|Blautia	186801|Clostridia	F	Psort location Cytoplasmic, score 8.87	gmk_1	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
NFNHFNFO_04503	33035.JPJF01000149_gene1707	1.53e-233	643.0	COG2812@1|root,COG2812@2|Bacteria,1VCQC@1239|Firmicutes,248U4@186801|Clostridia,3XYMK@572511|Blautia	186801|Clostridia	L	ATPase involved in DNA replication	holB	-	2.7.7.7	ko:K02341	ko00230,ko00240,ko01100,ko03030,ko03430,ko03440,map00230,map00240,map01100,map03030,map03430,map03440	M00260	R00375,R00376,R00377,R00378	RC02795	ko00000,ko00001,ko00002,ko01000,ko03032,ko03400	-	-	-	DNA_pol3_delta2,DNApol3-delta_C
NFNHFNFO_04504	33035.JPJF01000149_gene1708	9.73e-197	546.0	COG1774@1|root,COG1774@2|Bacteria,1TP1V@1239|Firmicutes,247Q6@186801|Clostridia,3XYM3@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yaaT	-	-	-	-	-	-	-	-	-	-	-	PSP1
NFNHFNFO_04505	33035.JPJF01000149_gene1709	4.76e-170	476.0	COG4123@1|root,COG4123@2|Bacteria,1TQ25@1239|Firmicutes,249UH@186801|Clostridia,3XZ60@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	yfiC	-	2.1.1.223	ko:K15460	-	-	-	-	ko00000,ko01000,ko03016	-	-	-	MTS,Methyltransf_31
NFNHFNFO_04506	33035.JPJF01000149_gene1710	2.76e-186	519.0	COG0313@1|root,COG0313@2|Bacteria,1TP6U@1239|Firmicutes,24864@186801|Clostridia,3XYJ8@572511|Blautia	186801|Clostridia	H	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA	rsmI	-	2.1.1.198	ko:K07056	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	TP_methylase
NFNHFNFO_04507	33035.JPJF01000035_gene3520	1.49e-212	592.0	COG2843@1|root,COG2843@2|Bacteria,1UCFI@1239|Firmicutes,25CHR@186801|Clostridia,3XZ2C@572511|Blautia	186801|Clostridia	M	Bacterial capsule synthesis protein PGA_cap	-	-	-	ko:K07282	-	-	-	-	ko00000	-	-	-	PGA_cap
NFNHFNFO_04508	33035.JPJF01000035_gene3518	2.84e-108	319.0	COG0388@1|root,COG0388@2|Bacteria,1TQDK@1239|Firmicutes,24AWV@186801|Clostridia,3XZQD@572511|Blautia	186801|Clostridia	S	Carbon-nitrogen hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	CN_hydrolase
NFNHFNFO_04509	33035.JPJF01000035_gene3517	1.15e-128	368.0	COG2715@1|root,COG2715@2|Bacteria,1V1E2@1239|Firmicutes,249G0@186801|Clostridia,3XZVF@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	spmA	-	-	ko:K06373	-	-	-	-	ko00000	-	-	-	Gate
NFNHFNFO_04510	33035.JPJF01000035_gene3508	4.3e-205	572.0	COG1609@1|root,COG1609@2|Bacteria,1UK1H@1239|Firmicutes,249XN@186801|Clostridia,3XZFY@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_04511	33035.JPJF01000035_gene3507	2.34e-239	659.0	COG1609@1|root,COG1609@2|Bacteria,1UK1H@1239|Firmicutes,249XN@186801|Clostridia,3XZFY@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_04512	33035.JPJF01000035_gene3506	2.26e-245	676.0	COG0715@1|root,COG0715@2|Bacteria,1UZFI@1239|Firmicutes,24E11@186801|Clostridia	186801|Clostridia	P	NMT1-like family	-	-	-	ko:K15553	ko00920,ko02010,map00920,map02010	M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.17.2	-	-	NMT1
NFNHFNFO_04513	33035.JPJF01000035_gene3505	2.88e-185	516.0	COG0600@1|root,COG0600@2|Bacteria,1TR6A@1239|Firmicutes,247VM@186801|Clostridia,3Y0M7@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02050,ko:K15552,ko:K15554	ko00920,ko02010,map00920,map02010	M00188,M00435,M00436	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.1,3.A.1.17.2,3.A.1.17.4	-	-	BPD_transp_1
NFNHFNFO_04514	33035.JPJF01000035_gene3504	4.04e-167	469.0	COG0600@1|root,COG0600@2|Bacteria,1UXRD@1239|Firmicutes,25MD8@186801|Clostridia,3Y1JP@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04515	33035.JPJF01000035_gene3503	4.76e-169	473.0	COG1116@1|root,COG1116@2|Bacteria,1TRM6@1239|Firmicutes,248CG@186801|Clostridia,3Y02Z@572511|Blautia	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049	-	M00188	-	-	ko00000,ko00002,ko02000	3.A.1.16,3.A.1.17	-	-	ABC_tran
NFNHFNFO_04516	33035.JPJF01000035_gene3502	2.22e-175	489.0	COG1116@1|root,COG1116@2|Bacteria,1TWYU@1239|Firmicutes,249UM@186801|Clostridia,3Y10Y@572511|Blautia	186801|Clostridia	P	ATPases associated with a variety of cellular activities	-	-	-	ko:K02049,ko:K15555	ko00920,ko02010,map00920,map02010	M00188,M00436	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.16,3.A.1.17,3.A.1.17.2	-	-	ABC_tran
NFNHFNFO_04517	33035.JPJF01000035_gene3501	9.78e-148	420.0	COG1028@1|root,COG1028@2|Bacteria,1UYV1@1239|Firmicutes,24NUW@186801|Clostridia,3Y1Q4@572511|Blautia	186801|Clostridia	IQ	Enoyl-(Acyl carrier protein) reductase	-	-	-	-	-	-	-	-	-	-	-	-	adh_short_C2
NFNHFNFO_04518	33035.JPJF01000035_gene3500	1.06e-172	484.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZ3S@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
NFNHFNFO_04519	33035.JPJF01000035_gene3499	7.51e-196	546.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,3XZRN@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
NFNHFNFO_04520	33035.JPJF01000035_gene3498	5.42e-209	581.0	COG1063@1|root,COG1063@2|Bacteria,1TPWP@1239|Firmicutes,24ATV@186801|Clostridia,3Y04Y@572511|Blautia	186801|Clostridia	C	Alcohol dehydrogenase GroES-like domain	-	-	1.1.1.14	ko:K00008	ko00040,ko00051,ko01100,map00040,map00051,map01100	M00014	R00875,R01896	RC00085,RC00102	ko00000,ko00001,ko00002,ko01000	-	-	-	ADH_N,ADH_zinc_N
NFNHFNFO_04521	33035.JPJF01000035_gene3497	5.86e-129	369.0	COG0036@1|root,COG0036@2|Bacteria,1TQK8@1239|Firmicutes,248AR@186801|Clostridia,3XZY7@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K17195	ko00051,ko01120,map00051,map01120	-	R09031	RC03111	ko00000,ko00001,ko01000	-	-	-	Ribul_P_3_epim
NFNHFNFO_04522	33035.JPJF01000035_gene3496	3.4e-151	427.0	COG0235@1|root,COG0235@2|Bacteria,1TPDV@1239|Firmicutes,248KI@186801|Clostridia,3XYMH@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Aldolase_II
NFNHFNFO_04523	33035.JPJF01000035_gene3495	1.35e-176	496.0	COG0149@1|root,COG0149@2|Bacteria,1UY0I@1239|Firmicutes,248YC@186801|Clostridia,3XZDR@572511|Blautia	186801|Clostridia	G	Triosephosphate isomerase	-	-	5.3.1.1	ko:K01803	ko00010,ko00051,ko00562,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00051,map00562,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00002,M00003	R01015	RC00423	ko00000,ko00001,ko00002,ko01000,ko04147	-	-	-	TIM
NFNHFNFO_04524	33035.JPJF01000035_gene3494	0.0	949.0	COG3875@1|root,COG3875@2|Bacteria,1TQ1C@1239|Firmicutes,247PH@186801|Clostridia,3XYNS@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF2088)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2088
NFNHFNFO_04525	33035.JPJF01000035_gene3492	3.28e-67	206.0	2E8MK@1|root,332Z1@2|Bacteria,1VEEU@1239|Firmicutes,24MU8@186801|Clostridia,3Y0HA@572511|Blautia	186801|Clostridia	S	Domain of unknown function (DUF4430)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4430
NFNHFNFO_04526	33035.JPJF01000035_gene3491	3.94e-103	300.0	2DMMK@1|root,32SFZ@2|Bacteria,1VARW@1239|Firmicutes,24NN3@186801|Clostridia,3Y1M4@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04527	33035.JPJF01000035_gene3490	2.4e-258	712.0	COG1228@1|root,COG1228@2|Bacteria,1TPNQ@1239|Firmicutes,248UT@186801|Clostridia	186801|Clostridia	Q	amidohydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1,Amidohydro_3
NFNHFNFO_04528	33035.JPJF01000035_gene3489	7.54e-316	865.0	COG0069@1|root,COG0069@2|Bacteria,1TQ0B@1239|Firmicutes,248IB@186801|Clostridia,3XZ2S@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	gltB	-	1.4.1.13,1.4.1.14	ko:K00265	ko00250,ko00910,ko01100,ko01110,ko01120,ko01130,ko01230,map00250,map00910,map01100,map01110,map01120,map01130,map01230	-	R00093,R00114,R00248	RC00006,RC00010,RC02799	ko00000,ko00001,ko01000	-	-	-	Fer4,Fer4_7,Fer4_9,Glu_syn_central,Glu_synthase
NFNHFNFO_04529	33035.JPJF01000035_gene3488	7.25e-302	826.0	COG0534@1|root,COG0534@2|Bacteria,1TNZN@1239|Firmicutes,247YX@186801|Clostridia,3XYPG@572511|Blautia	186801|Clostridia	V	COG COG0534 Na -driven multidrug efflux pump	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_04530	33035.JPJF01000035_gene3487	1.48e-163	461.0	COG0253@1|root,COG0253@2|Bacteria,1V77F@1239|Firmicutes,24H7N@186801|Clostridia,3Y18W@572511|Blautia	186801|Clostridia	E	COG0253 Diaminopimelate epimerase	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04531	33035.JPJF01000035_gene3486	2.11e-157	441.0	2DRRG@1|root,32URH@2|Bacteria,1VCR2@1239|Firmicutes,24PBW@186801|Clostridia,3Y1I6@572511|Blautia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04532	180332.JTGN01000002_gene5657	3.25e-186	533.0	COG1653@1|root,COG1653@2|Bacteria,1TR5H@1239|Firmicutes,24977@186801|Clostridia	186801|Clostridia	G	PFAM extracellular solute-binding protein family 1	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_04533	180332.JTGN01000002_gene5658	1.25e-172	486.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia	186801|Clostridia	P	PFAM binding-protein-dependent transport systems inner membrane component	-	-	-	ko:K10118	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_04534	180332.JTGN01000002_gene5659	1.64e-111	330.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia	186801|Clostridia	P	ABC-type sugar transport system, permease component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_04535	180332.JTGN01000002_gene5660	2.38e-101	304.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1V27N@1239|Firmicutes,24EUU@186801|Clostridia	186801|Clostridia	T	response regulator receiver	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,Response_reg
NFNHFNFO_04536	180332.JTGN01000002_gene5661	8.46e-180	527.0	COG2972@1|root,COG2972@2|Bacteria,1V4G9@1239|Firmicutes,24IA9@186801|Clostridia	186801|Clostridia	T	Histidine kinase	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase
NFNHFNFO_04537	33035.JPJF01000035_gene3485	0.0	1341.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3XYX5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NFNHFNFO_04538	180332.JTGN01000013_gene866	2.08e-168	502.0	COG5002@1|root,COG5002@2|Bacteria,1UINY@1239|Firmicutes,25EPM@186801|Clostridia	186801|Clostridia	T	ATP-binding region ATPase domain protein	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5
NFNHFNFO_04540	537007.BLAHAN_06570	1.65e-61	191.0	2BHVP@1|root,32BZI@2|Bacteria,1TV20@1239|Firmicutes,2597A@186801|Clostridia,3Y1P1@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04541	1163671.JAGI01000002_gene3159	1.68e-64	198.0	COG3436@1|root,COG3436@2|Bacteria,1V7U9@1239|Firmicutes,24K4W@186801|Clostridia,36KTF@31979|Clostridiaceae	186801|Clostridia	L	PFAM IS66 Orf2 family protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
NFNHFNFO_04542	742733.HMPREF9469_05985	8.95e-40	136.0	COG2963@1|root,COG2963@2|Bacteria,1VF0P@1239|Firmicutes,25D6V@186801|Clostridia	186801|Clostridia	L	transposase activity	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04543	349161.Dred_0303	3.58e-26	109.0	COG4584@1|root,COG4584@2|Bacteria,1TNY9@1239|Firmicutes,24B59@186801|Clostridia,263V0@186807|Peptococcaceae	186801|Clostridia	L	Integrase	-	-	-	-	-	-	-	-	-	-	-	-	rve
NFNHFNFO_04545	1392487.JIAD01000001_gene1579	3.34e-41	143.0	COG1484@1|root,COG1484@2|Bacteria,1TQBX@1239|Firmicutes,249T2@186801|Clostridia,25X6Y@186806|Eubacteriaceae	186801|Clostridia	L	IstB-like ATP binding protein	-	-	-	-	-	-	-	-	-	-	-	-	IstB_IS21,IstB_IS21_ATP
NFNHFNFO_04546	556261.HMPREF0240_01185	8.81e-89	261.0	28IAH@1|root,33CBZ@2|Bacteria,1VNQF@1239|Firmicutes,24J5I@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04547	556261.HMPREF0240_01186	4.56e-80	237.0	COG3436@1|root,COG3436@2|Bacteria,1V7U9@1239|Firmicutes,24K4W@186801|Clostridia,36KTF@31979|Clostridiaceae	186801|Clostridia	L	PFAM IS66 Orf2 family protein	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	TnpB_IS66
NFNHFNFO_04548	556261.HMPREF0240_01187	1.5e-154	447.0	COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,251Y5@186801|Clostridia,36UP2@31979|Clostridiaceae	186801|Clostridia	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
NFNHFNFO_04549	556261.HMPREF0240_01187	1.89e-205	578.0	COG3316@1|root,COG3316@2|Bacteria,1VZPC@1239|Firmicutes,251Y5@186801|Clostridia,36UP2@31979|Clostridiaceae	186801|Clostridia	L	Transposase IS66 family	-	-	-	ko:K07484	-	-	-	-	ko00000	-	-	-	DDE_Tnp_IS66,DDE_Tnp_IS66_C,LZ_Tnp_IS66,zf-IS66
NFNHFNFO_04550	537007.BLAHAN_05931	2.06e-92	278.0	COG3464@1|root,COG3464@2|Bacteria,1VDMT@1239|Firmicutes,24N28@186801|Clostridia	186801|Clostridia	L	Transposase	-	-	-	-	-	-	-	-	-	-	-	-	DDE_Tnp_ISL3
NFNHFNFO_04551	411459.RUMOBE_02913	7.35e-273	749.0	COG1004@1|root,COG1004@2|Bacteria,1TQFN@1239|Firmicutes,25B1W@186801|Clostridia,3XZF2@572511|Blautia	186801|Clostridia	M	Belongs to the UDP-glucose GDP-mannose dehydrogenase family	-	-	1.1.1.22	ko:K00012	ko00040,ko00053,ko00520,ko01100,map00040,map00053,map00520,map01100	M00014,M00129,M00361,M00362	R00286	RC00291	ko00000,ko00001,ko00002,ko01000	-	-	-	HTH_3,UDPG_MGDP_dh,UDPG_MGDP_dh_C,UDPG_MGDP_dh_N
NFNHFNFO_04552	411459.RUMOBE_02912	6.23e-159	451.0	2CKKB@1|root,3479Y@2|Bacteria,1VYTQ@1239|Firmicutes,253C5@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04553	411459.RUMOBE_02911	8.42e-68	219.0	COG2244@1|root,COG2244@2|Bacteria,1TRRI@1239|Firmicutes,24EFD@186801|Clostridia,3Y1JC@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
NFNHFNFO_04554	411459.RUMOBE_02911	1.51e-207	584.0	COG2244@1|root,COG2244@2|Bacteria,1TRRI@1239|Firmicutes,24EFD@186801|Clostridia,3Y1JC@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt,Polysacc_synt_C
NFNHFNFO_04555	411459.RUMOBE_02910	2.73e-237	658.0	2CKKA@1|root,345HU@2|Bacteria,1VZ7J@1239|Firmicutes,252W8@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04556	411459.RUMOBE_02909	9.88e-263	720.0	COG0535@1|root,COG0535@2|Bacteria,1V2JB@1239|Firmicutes,24G9M@186801|Clostridia	186801|Clostridia	E	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NFNHFNFO_04557	411459.RUMOBE_02908	1.31e-202	566.0	COG5039@1|root,COG5039@2|Bacteria,1V5MK@1239|Firmicutes,24I9A@186801|Clostridia	186801|Clostridia	GM	Polysaccharide pyruvyl transferase	-	-	-	-	-	-	-	-	-	-	-	-	PS_pyruv_trans
NFNHFNFO_04558	411459.RUMOBE_02907	5.73e-152	431.0	COG1216@1|root,COG1216@2|Bacteria,1VDZ5@1239|Firmicutes,24FMY@186801|Clostridia	186801|Clostridia	M	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Glycos_transf_2
NFNHFNFO_04559	411459.RUMOBE_02906	4.19e-161	453.0	COG0463@1|root,COG0463@2|Bacteria,1TSFF@1239|Firmicutes,24IBH@186801|Clostridia,3Y0QP@572511|Blautia	186801|Clostridia	M	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K12997,ko:K16698	-	-	-	-	ko00000,ko01000,ko01003,ko01005	-	GT2	-	Glycos_transf_2
NFNHFNFO_04560	411459.RUMOBE_02905	6.99e-144	407.0	COG2148@1|root,COG2148@2|Bacteria,1TP7V@1239|Firmicutes,25AZD@186801|Clostridia,3Y00N@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
NFNHFNFO_04561	1123489.AUAN01000002_gene658	1.67e-217	609.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,4H2HH@909932|Negativicutes	909932|Negativicutes	E	Belongs to the DegT DnrJ EryC1 family	-	-	-	-	-	-	-	-	-	-	-	-	DegT_DnrJ_EryC1
NFNHFNFO_04563	411902.CLOBOL_01227	2.69e-33	125.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,21ZQG@1506553|Lachnoclostridium	186801|Clostridia	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
NFNHFNFO_04564	742735.HMPREF9467_00460	1.42e-14	74.7	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,21Y82@1506553|Lachnoclostridium	186801|Clostridia	E	DegT/DnrJ/EryC1/StrS aminotransferase family	-	-	2.6.1.102	ko:K13010	ko00520,map00520	-	R10460	RC00006,RC00781	ko00000,ko00001,ko01000,ko01005,ko01007	-	-	-	DegT_DnrJ_EryC1
NFNHFNFO_04565	33035.JPJF01000042_gene362	0.0	1296.0	COG1086@1|root,COG1086@2|Bacteria,1TR3W@1239|Firmicutes,247PW@186801|Clostridia,3XYZJ@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	capD	-	-	-	-	-	-	-	-	-	-	-	CoA_binding_3,Polysacc_synt_2
NFNHFNFO_04566	33035.JPJF01000042_gene361	1.36e-287	785.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24EJK@186801|Clostridia,3Y163@572511|Blautia	186801|Clostridia	L	Putative transposase DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
NFNHFNFO_04567	33035.JPJF01000065_gene5077	3.53e-256	704.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24B23@186801|Clostridia,3Y00V@572511|Blautia	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
NFNHFNFO_04568	33035.JPJF01000013_gene4532	1.17e-305	836.0	COG0770@1|root,COG0770@2|Bacteria,1VT78@1239|Firmicutes,25100@186801|Clostridia,3XZFT@572511|Blautia	186801|Clostridia	M	Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein	murF	-	6.3.2.10	ko:K01929	ko00300,ko00550,ko01100,ko01502,map00300,map00550,map01100,map01502	-	R04573,R04617	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Mur_ligase,Mur_ligase_C,Mur_ligase_M
NFNHFNFO_04569	33035.JPJF01000013_gene4533	6.71e-241	662.0	COG1181@1|root,COG1181@2|Bacteria,1TP2Y@1239|Firmicutes,248CR@186801|Clostridia,3XYIN@572511|Blautia	186801|Clostridia	M	Belongs to the D-alanine--D-alanine ligase family	ddl	-	6.3.2.4	ko:K01921	ko00473,ko00550,ko01100,ko01502,map00473,map00550,map01100,map01502	-	R01150	RC00064,RC00141	ko00000,ko00001,ko01000,ko01011	-	-	-	Dala_Dala_lig_C,Dala_Dala_lig_N
NFNHFNFO_04570	33035.JPJF01000013_gene4534	1.14e-200	557.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,3XZEN@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_04571	33035.JPJF01000013_gene4535	0.0	2182.0	COG1196@1|root,COG2273@1|root,COG5263@1|root,COG1196@2|Bacteria,COG2273@2|Bacteria,COG5263@2|Bacteria,1UUUJ@1239|Firmicutes,25KCI@186801|Clostridia,3Y1HA@572511|Blautia	186801|Clostridia	G	Putative cell wall binding repeat	-	-	3.2.1.35	ko:K01197	ko00531,ko01100,map00531,map01100	M00076,M00077	R07824,R07825,R10905	-	ko00000,ko00001,ko00002,ko00536,ko00537,ko01000,ko02042	-	-	-	CW_binding_1,F5_F8_type_C
NFNHFNFO_04572	33035.JPJF01000013_gene4536	0.0	921.0	COG1376@1|root,COG1376@2|Bacteria,1TQMA@1239|Firmicutes,248H0@186801|Clostridia,3XYNG@572511|Blautia	186801|Clostridia	S	protein conserved in bacteria	-	-	-	-	-	-	-	-	-	-	-	-	PG_binding_4,YkuD
NFNHFNFO_04573	33035.JPJF01000013_gene4537	8.36e-308	840.0	COG1167@1|root,COG1167@2|Bacteria,1TPMY@1239|Firmicutes,24986@186801|Clostridia,3XZB7@572511|Blautia	186801|Clostridia	EK	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Aminotran_MocR
NFNHFNFO_04574	33035.JPJF01000013_gene4538	0.0	1575.0	COG0474@1|root,COG0474@2|Bacteria,1TPF5@1239|Firmicutes,247JN@186801|Clostridia,3XZ58@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	3.6.3.8	ko:K01537	-	-	-	-	ko00000,ko01000	3.A.3.2	-	-	Cation_ATPase_C,Cation_ATPase_N,E1-E2_ATPase,Hydrolase
NFNHFNFO_04575	33035.JPJF01000013_gene4539	1.48e-214	591.0	COG1092@1|root,COG1092@2|Bacteria,1TPUD@1239|Firmicutes,2480X@186801|Clostridia,3XYN6@572511|Blautia	186801|Clostridia	H	S-adenosylmethionine-dependent methyltransferase	rlmL_1	-	2.1.1.191	ko:K06969	-	-	-	-	ko00000,ko01000,ko03009	-	-	-	Methyltrans_SAM
NFNHFNFO_04576	33035.JPJF01000013_gene4545	3.07e-81	249.0	COG3212@1|root,COG3212@2|Bacteria,1VCWB@1239|Firmicutes,24NZX@186801|Clostridia,3Y0I3@572511|Blautia	186801|Clostridia	S	Peptidase propeptide and YPEB domain	-	-	-	-	-	-	-	-	-	-	-	-	PepSY
NFNHFNFO_04577	33035.JPJF01000013_gene4546	1.2e-263	730.0	COG5000@1|root,COG5002@1|root,COG5000@2|Bacteria,COG5002@2|Bacteria,1TPSK@1239|Firmicutes,24A2N@186801|Clostridia,3XZDQ@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score 10.00	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,HisKA
NFNHFNFO_04578	33035.JPJF01000013_gene4547	6.58e-152	427.0	COG0745@1|root,COG0745@2|Bacteria,1TS81@1239|Firmicutes,248XH@186801|Clostridia,3XYM2@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.55	mprA	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_04579	33035.JPJF01000013_gene4548	7.36e-55	171.0	COG3326@1|root,COG3326@2|Bacteria,1VEJY@1239|Firmicutes,24QJW@186801|Clostridia,3Y0K2@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	DUF1294
NFNHFNFO_04580	33035.JPJF01000013_gene4549	4.32e-234	645.0	COG0252@1|root,COG0252@2|Bacteria,1TPP9@1239|Firmicutes,248F3@186801|Clostridia,3XZG1@572511|Blautia	186801|Clostridia	EJ	Psort location Cytoplasmic, score	ansA	-	3.5.1.1	ko:K01424	ko00250,ko00460,ko01100,ko01110,map00250,map00460,map01100,map01110	-	R00485	RC00010,RC02798	ko00000,ko00001,ko01000	-	-	-	Asparaginase
NFNHFNFO_04581	33035.JPJF01000013_gene4550	2.64e-246	678.0	COG0082@1|root,COG0082@2|Bacteria,1TQ40@1239|Firmicutes,24998@186801|Clostridia,3XZ4P@572511|Blautia	186801|Clostridia	E	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system	aroC	-	4.2.3.5	ko:K01736	ko00400,ko01100,ko01110,ko01130,ko01230,map00400,map01100,map01110,map01130,map01230	M00022	R01714	RC00586	ko00000,ko00001,ko00002,ko01000	-	-	-	Chorismate_synt
NFNHFNFO_04582	33035.JPJF01000013_gene4551	6.85e-165	461.0	COG0745@1|root,COG0745@2|Bacteria,1TP9M@1239|Firmicutes,247TK@186801|Clostridia,3XYJK@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	vanR3	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_04583	33035.JPJF01000013_gene4552	0.0	1348.0	COG0642@1|root,COG2205@2|Bacteria,1TP73@1239|Firmicutes,248Y6@186801|Clostridia,3XZAZ@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_04584	33035.JPJF01000013_gene4553	0.0	1294.0	COG3250@1|root,COG3250@2|Bacteria,1TS96@1239|Firmicutes,24FH0@186801|Clostridia	186801|Clostridia	G	Belongs to the glycosyl hydrolase 2 family	-	-	3.2.1.25	ko:K01192	ko00511,ko04142,map00511,map04142	-	-	-	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFNHFNFO_04585	33035.JPJF01000013_gene4554	3.48e-184	514.0	COG0395@1|root,COG0395@2|Bacteria,1UXJD@1239|Firmicutes,25M52@186801|Clostridia,3Y1KD@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04586	33035.JPJF01000013_gene4555	2.15e-183	513.0	COG1175@1|root,COG1175@2|Bacteria,1UXJE@1239|Firmicutes,25MIM@186801|Clostridia,3Y1QD@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	-	-	-	-	-	-	-	-	-	BPD_transp_1
NFNHFNFO_04587	33035.JPJF01000013_gene4556	4.53e-266	735.0	COG1653@1|root,COG1653@2|Bacteria,1UUUK@1239|Firmicutes,25MFP@186801|Clostridia,3Y1WB@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	ko:K10117	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	SBP_bac_8
NFNHFNFO_04588	1226325.HMPREF1548_06731	2.79e-293	808.0	COG3534@1|root,COG3534@2|Bacteria,1TR7B@1239|Firmicutes,248ZA@186801|Clostridia,36DY3@31979|Clostridiaceae	186801|Clostridia	G	Alpha-L-arabinofuranosidase	-	-	-	-	-	-	-	-	-	-	-	-	Alpha-L-AF_C,Laminin_G_3
NFNHFNFO_04589	33035.JPJF01000013_gene4557	0.0	1050.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3Y1IV@572511|Blautia	186801|Clostridia	T	Cache domain	-	-	-	-	-	-	-	-	-	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NFNHFNFO_04590	33035.JPJF01000013_gene4558	0.0	928.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3Y1R1@572511|Blautia	186801|Clostridia	T	helix_turn_helix, arabinose operon control protein	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NFNHFNFO_04591	33035.JPJF01000013_gene4559	1.48e-196	547.0	COG0679@1|root,COG0679@2|Bacteria,1V0ZS@1239|Firmicutes,24CQ0@186801|Clostridia	186801|Clostridia	S	PFAM Auxin Efflux Carrier	-	-	-	ko:K07088	-	-	-	-	ko00000	-	-	-	Mem_trans
NFNHFNFO_04592	33035.JPJF01000141_gene2442	6.35e-158	449.0	28M3R@1|root,2ZAHU@2|Bacteria,1TR3Y@1239|Firmicutes,249MC@186801|Clostridia,3XZ6X@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04593	33035.JPJF01000013_gene4560	1.71e-107	312.0	COG1335@1|root,COG1335@2|Bacteria,1V1CY@1239|Firmicutes,24HQM@186801|Clostridia,3Y05Q@572511|Blautia	186801|Clostridia	Q	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Isochorismatase
NFNHFNFO_04594	33035.JPJF01000013_gene4561	2.09e-225	624.0	COG3426@1|root,COG3426@2|Bacteria,1TPKE@1239|Firmicutes,24993@186801|Clostridia,3Y104@572511|Blautia	186801|Clostridia	C	Acetokinase family	buk	-	2.7.2.7	ko:K00929	ko00650,ko01100,map00650,map01100	-	R01688	RC00002,RC00043	ko00000,ko00001,ko01000	-	-	-	Acetate_kinase
NFNHFNFO_04595	33035.JPJF01000013_gene4562	1.85e-119	344.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia,3XZ6F@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
NFNHFNFO_04596	33035.JPJF01000013_gene4563	1.45e-297	813.0	COG4908@1|root,COG4908@2|Bacteria,1TQXH@1239|Firmicutes,24B2C@186801|Clostridia,3XZ6F@572511|Blautia	186801|Clostridia	S	Psort location	-	-	-	-	-	-	-	-	-	-	-	-	AATase
NFNHFNFO_04597	33035.JPJF01000013_gene4564	1.98e-230	635.0	COG0657@1|root,COG0657@2|Bacteria,1TQHX@1239|Firmicutes,249GM@186801|Clostridia,3XZT2@572511|Blautia	186801|Clostridia	I	Steryl acetyl hydrolase	-	-	-	-	-	-	-	-	-	-	-	-	Abhydrolase_3
NFNHFNFO_04598	33035.JPJF01000013_gene4565	4.66e-128	363.0	COG5423@1|root,COG5423@2|Bacteria,1V8Y4@1239|Firmicutes,24EAF@186801|Clostridia	186801|Clostridia	S	Predicted metal-binding protein (DUF2284)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2284
NFNHFNFO_04599	33035.JPJF01000013_gene4579	3.41e-123	354.0	COG3544@1|root,COG3544@2|Bacteria,1V6WE@1239|Firmicutes,24KNZ@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF305)	-	-	-	-	-	-	-	-	-	-	-	-	DUF305
NFNHFNFO_04600	33035.JPJF01000013_gene4586	0.0	1036.0	COG1966@1|root,COG1966@2|Bacteria,1TQN8@1239|Firmicutes,248DZ@186801|Clostridia,3Y0FH@572511|Blautia	186801|Clostridia	T	Psort location CytoplasmicMembrane, score 9.99	cstA	-	-	ko:K06200	-	-	-	-	ko00000	-	-	-	CstA,CstA_5TM
NFNHFNFO_04601	33035.JPJF01000013_gene4587	4.92e-110	318.0	2DMWJ@1|root,32U4E@2|Bacteria,1VH8Q@1239|Firmicutes,25HNA@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04602	33035.JPJF01000013_gene4588	1.42e-76	231.0	COG3467@1|root,COG3467@2|Bacteria,1UUUN@1239|Firmicutes,25KCK@186801|Clostridia,3Y1RN@572511|Blautia	186801|Clostridia	S	Pyridoxamine 5'-phosphate oxidase	-	-	-	-	-	-	-	-	-	-	-	-	Pyridox_ox_2
NFNHFNFO_04603	33035.JPJF01000013_gene4595	0.0	983.0	COG0369@1|root,COG1151@2|Bacteria,1TP8X@1239|Firmicutes,247IN@186801|Clostridia,3XZ89@572511|Blautia	186801|Clostridia	C	Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O	hcp	-	1.7.99.1	ko:K05601	ko00910,map00910	-	R00143	RC02797	ko00000,ko00001,ko01000	-	-	-	Prismane
NFNHFNFO_04604	33035.JPJF01000013_gene4596	9.66e-97	285.0	COG1145@1|root,COG1145@2|Bacteria,1TPAZ@1239|Firmicutes,249NJ@186801|Clostridia,3XZ8P@572511|Blautia	186801|Clostridia	C	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Fer4,Fer4_6
NFNHFNFO_04605	33035.JPJF01000013_gene4597	7.39e-147	414.0	COG0664@1|root,COG0664@2|Bacteria,1TSP9@1239|Firmicutes,24FRD@186801|Clostridia,3XZ4Z@572511|Blautia	186801|Clostridia	K	COG COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases	-	-	-	-	-	-	-	-	-	-	-	-	HTH_Crp_2,cNMP_binding
NFNHFNFO_04606	33035.JPJF01000013_gene4598	9.66e-252	692.0	COG1509@1|root,COG1509@2|Bacteria,1TQQZ@1239|Firmicutes,249JV@186801|Clostridia	186801|Clostridia	E	TIGRFAM lysine 2,3-aminomutase YodO family protein	-	-	-	-	-	-	-	-	-	-	-	-	Radical_SAM
NFNHFNFO_04607	1232453.BAIF02000054_gene1190	4.74e-32	116.0	COG0454@1|root,COG0456@2|Bacteria,1VBFC@1239|Firmicutes,24KAJ@186801|Clostridia,26B8J@186813|unclassified Clostridiales	186801|Clostridia	K	FR47-like protein	bltD	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
NFNHFNFO_04608	658088.HMPREF0987_01089	9.11e-170	473.0	2DZ28@1|root,32V6H@2|Bacteria,1VCMH@1239|Firmicutes,24QBQ@186801|Clostridia,27QVA@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04609	658088.HMPREF0987_01090	9.87e-70	210.0	COG1476@1|root,COG1476@2|Bacteria,1UMEJ@1239|Firmicutes,25GM4@186801|Clostridia	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_26,HTH_3
NFNHFNFO_04610	658088.HMPREF0987_01091	1.58e-70	212.0	COG1396@1|root,COG1396@2|Bacteria,1VID8@1239|Firmicutes,25GM5@186801|Clostridia,27Q6U@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Cro/C1-type HTH DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_3
NFNHFNFO_04611	658088.HMPREF0987_01092	6.54e-40	132.0	29UZW@1|root,30GCX@2|Bacteria,1UFRZ@1239|Firmicutes,25MJP@186801|Clostridia,27SCI@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04612	658088.HMPREF0987_01093	8.54e-28	100.0	29U8H@1|root,30FIH@2|Bacteria,1UE3E@1239|Firmicutes,25IXN@186801|Clostridia,27SXN@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04613	658088.HMPREF0987_01094	2.39e-85	251.0	COG1396@1|root,COG1396@2|Bacteria,1VGAT@1239|Firmicutes,24QWH@186801|Clostridia,27Q5F@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Helix-turn-helix domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3
NFNHFNFO_04614	658088.HMPREF0987_01095	0.0	1226.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,2492M@186801|Clostridia,27M1U@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase
NFNHFNFO_04615	658655.HMPREF0988_00516	3.56e-188	522.0	COG1961@1|root,COG1961@2|Bacteria,1V247@1239|Firmicutes,24GH4@186801|Clostridia,27MEZ@186928|unclassified Lachnospiraceae	186801|Clostridia	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04616	658088.HMPREF0987_01097	1.72e-91	267.0	2C62A@1|root,33P1Y@2|Bacteria,1VP22@1239|Firmicutes,24T2I@186801|Clostridia,27RHH@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04617	658088.HMPREF0987_01098	5.42e-227	625.0	COG1475@1|root,COG1475@2|Bacteria,1V2SD@1239|Firmicutes,24GNZ@186801|Clostridia,27Q08@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04618	658088.HMPREF0987_01099	4.25e-219	604.0	COG1475@1|root,COG1475@2|Bacteria,1UYXH@1239|Firmicutes,24B4U@186801|Clostridia,27M1N@186928|unclassified Lachnospiraceae	186801|Clostridia	K	DNA binding	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04619	658088.HMPREF0987_01100	0.0	922.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,248J7@186801|Clostridia,27J3U@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NFNHFNFO_04620	658088.HMPREF0987_01101	0.0	986.0	COG1961@1|root,COG1961@2|Bacteria,1TPBH@1239|Firmicutes,24EUS@186801|Clostridia,27KUD@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Recombinase zinc beta ribbon domain	-	-	-	-	-	-	-	-	-	-	-	-	Recombinase,Resolvase,Zn_ribbon_recom
NFNHFNFO_04621	658655.HMPREF0988_00523	5.46e-233	640.0	COG0860@1|root,COG5632@1|root,COG0860@2|Bacteria,COG5632@2|Bacteria,1TUB7@1239|Firmicutes,25B8N@186801|Clostridia,27U0C@186928|unclassified Lachnospiraceae	186801|Clostridia	M	Ami_2	-	-	-	-	-	-	-	-	-	-	-	-	Amidase_2,LysM,SH3_3,SPOR
NFNHFNFO_04622	658655.HMPREF0988_00524	1.92e-88	260.0	COG4824@1|root,COG4824@2|Bacteria,1V3TR@1239|Firmicutes,24HQ9@186801|Clostridia,27N2C@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacteriophage holin family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_holin_4_1
NFNHFNFO_04623	658088.HMPREF0987_01104	0.0	1131.0	COG4675@1|root,COG4675@2|Bacteria,1V63H@1239|Firmicutes,24CBR@186801|Clostridia,27K2S@186928|unclassified Lachnospiraceae	186801|Clostridia	S	the current gene model (or a revised gene model) may contain a frame shift	-	-	-	-	-	-	-	-	-	-	-	-	DUF859
NFNHFNFO_04624	658088.HMPREF0987_01105	6.8e-123	351.0	2DBDY@1|root,2Z8Q0@2|Bacteria,1UZPY@1239|Firmicutes,24BJG@186801|Clostridia,27RF8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04625	658655.HMPREF0988_00527	0.0	1144.0	28IEK@1|root,2Z8GM@2|Bacteria,1TQUU@1239|Firmicutes,24C6S@186801|Clostridia,27QWX@186928|unclassified Lachnospiraceae	186801|Clostridia	S	candidate retaining b-glycosidase, glycoside hydrolase family 5 protein K01238	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04626	658088.HMPREF0987_01107	0.0	956.0	COG4926@1|root,COG4926@2|Bacteria,1V80R@1239|Firmicutes,248JI@186801|Clostridia,27NK9@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Prophage endopeptidase tail	-	-	-	-	-	-	-	-	-	-	-	-	Prophage_tail
NFNHFNFO_04627	658088.HMPREF0987_01108	2.15e-153	431.0	28JA4@1|root,2Z94Z@2|Bacteria,1TR2M@1239|Firmicutes,24CMG@186801|Clostridia,27M0F@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04628	658088.HMPREF0987_01109	0.0	1553.0	COG5280@1|root,COG5412@1|root,COG5280@2|Bacteria,COG5412@2|Bacteria,1TQ28@1239|Firmicutes,247QT@186801|Clostridia,27J2F@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage-related minor tail protein	-	-	-	-	-	-	-	-	-	-	-	-	PhageMin_Tail,TMP
NFNHFNFO_04631	246199.CUS_4566	8.79e-21	100.0	COG4096@1|root,COG4096@2|Bacteria,1UI7V@1239|Firmicutes,25ED3@186801|Clostridia,3WIR6@541000|Ruminococcaceae	186801|Clostridia	L	COG COG4096 Type I site-specific restriction-modification system, R (restriction) subunit and related helicases	-	-	3.1.21.3	ko:K01153	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	EcoEI_R_C,HSDR_N,HSDR_N_2,Helicase_C,ResIII
NFNHFNFO_04632	658088.HMPREF0987_01112	2.21e-31	109.0	2BX2H@1|root,32Y2N@2|Bacteria,1VEEG@1239|Firmicutes,24RM5@186801|Clostridia,27PT3@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04633	658088.HMPREF0987_01113	6.46e-83	245.0	2990R@1|root,2ZW4F@2|Bacteria,1V3SD@1239|Firmicutes,24HA5@186801|Clostridia,27N4K@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04634	658655.HMPREF0988_00537	9.96e-135	382.0	28H7M@1|root,2Z7JU@2|Bacteria,1UG4F@1239|Firmicutes,24B1Y@186801|Clostridia,27JWC@186928|unclassified Lachnospiraceae	186801|Clostridia	S	phage major tail protein, phi13 family	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04635	658088.HMPREF0987_01115	2.67e-63	194.0	2CK6F@1|root,32SBP@2|Bacteria,1VA68@1239|Firmicutes,24NE8@186801|Clostridia,27NYW@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04636	658655.HMPREF0988_00539	1.11e-79	237.0	2E357@1|root,32Y56@2|Bacteria,1VEJA@1239|Firmicutes,24J80@186801|Clostridia,27Q25@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Bacteriophage HK97-gp10, putative tail-component	-	-	-	-	-	-	-	-	-	-	-	-	HK97-gp10_like
NFNHFNFO_04637	658655.HMPREF0988_00540	3.25e-81	240.0	COG5614@1|root,COG5614@2|Bacteria,1VBQZ@1239|Firmicutes,24MIT@186801|Clostridia,27N09@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage head-tail joining protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_H_T_join
NFNHFNFO_04638	658088.HMPREF0987_01118	5.64e-54	169.0	2E3C8@1|root,32YBI@2|Bacteria,1VETG@1239|Firmicutes,24QPC@186801|Clostridia,27PYH@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage gp6-like head-tail connector protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_connect_1
NFNHFNFO_04639	658088.HMPREF0987_01119	8.81e-284	776.0	COG4653@1|root,COG4653@2|Bacteria,1TS6A@1239|Firmicutes,24994@186801|Clostridia,27J63@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage capsid family	-	-	-	-	-	-	-	-	-	-	-	-	Phage_capsid
NFNHFNFO_04640	658088.HMPREF0987_01120	1.55e-160	450.0	COG0740@1|root,COG0740@2|Bacteria,1TR2H@1239|Firmicutes,249NC@186801|Clostridia,27JST@186928|unclassified Lachnospiraceae	186801|Clostridia	OU	Serine dehydrogenase proteinase	-	-	3.4.21.92	ko:K01358	ko04112,ko04212,map04112,map04212	-	-	-	ko00000,ko00001,ko01000,ko01002	-	-	-	CLP_protease
NFNHFNFO_04641	658088.HMPREF0987_01121	6.06e-312	848.0	COG4695@1|root,COG4695@2|Bacteria,1TP8B@1239|Firmicutes,2497C@186801|Clostridia,27I52@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage portal protein	-	-	-	-	-	-	-	-	-	-	-	-	Phage_portal
NFNHFNFO_04642	658655.HMPREF0988_00545	0.0	1063.0	COG4626@1|root,COG4626@2|Bacteria,1TPU1@1239|Firmicutes,248RI@186801|Clostridia,27IKB@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Phage Terminase	-	-	-	-	-	-	-	-	-	-	-	-	LAGLIDADG_3,Terminase_1
NFNHFNFO_04643	658655.HMPREF0988_00546	1.38e-112	323.0	COG3747@1|root,COG3747@2|Bacteria,1V0EC@1239|Firmicutes,24GCB@186801|Clostridia,27K65@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Phage terminase, small subunit	-	-	-	-	-	-	-	-	-	-	-	-	Terminase_4
NFNHFNFO_04645	658655.HMPREF0988_00548	3.94e-94	274.0	COG2105@1|root,COG2105@2|Bacteria,1VGQA@1239|Firmicutes,24S5K@186801|Clostridia,27Q1R@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Domain of unknown function (DUF4314)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4314
NFNHFNFO_04646	658655.HMPREF0988_00549	1.56e-92	271.0	COG2105@1|root,COG2105@2|Bacteria,1VDAD@1239|Firmicutes,24G9Y@186801|Clostridia,27TP0@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Gamma-glutamyl cyclotransferase, AIG2-like	-	-	-	-	-	-	-	-	-	-	-	-	GGACT
NFNHFNFO_04647	658655.HMPREF0988_00550	2.02e-216	597.0	28HR1@1|root,2Z7YI@2|Bacteria,1TRNR@1239|Firmicutes,2486X@186801|Clostridia,27JS2@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Putative amidoligase enzyme	-	-	-	-	-	-	-	-	-	-	-	-	Amidoligase_2
NFNHFNFO_04648	658655.HMPREF0988_00551	3.91e-168	471.0	2948F@1|root,32SNR@2|Bacteria,1V5VX@1239|Firmicutes,24IET@186801|Clostridia,27M7Y@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04649	658088.HMPREF0987_01128	1.75e-314	855.0	COG0270@1|root,COG0270@2|Bacteria,1TS3G@1239|Firmicutes,249Q9@186801|Clostridia,27KBU@186928|unclassified Lachnospiraceae	186801|Clostridia	H	C-5 cytosine-specific DNA methylase	-	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
NFNHFNFO_04650	658088.HMPREF0987_01129	1.18e-313	853.0	COG0863@1|root,COG1475@1|root,COG0863@2|Bacteria,COG1475@2|Bacteria,1TPHP@1239|Firmicutes,249MR@186801|Clostridia,27IY4@186928|unclassified Lachnospiraceae	186801|Clostridia	KL	DNA methylase	-	-	-	-	-	-	-	-	-	-	-	-	N6_N4_Mtase,ParBc
NFNHFNFO_04651	658088.HMPREF0987_01130	6.2e-112	320.0	COG1961@1|root,COG1961@2|Bacteria,1VA99@1239|Firmicutes,24MZH@186801|Clostridia,27M7F@186928|unclassified Lachnospiraceae	186801|Clostridia	L	COG1961 Site-specific recombinases, DNA invertase Pin homologs	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04652	658088.HMPREF0987_01132	1.27e-111	323.0	2DYQY@1|root,34ARP@2|Bacteria,1UGJ2@1239|Firmicutes,2533K@186801|Clostridia,27SU4@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
NFNHFNFO_04654	658655.HMPREF0988_00555	2.59e-231	637.0	COG2169@1|root,COG2169@2|Bacteria,1TR37@1239|Firmicutes,24A8S@186801|Clostridia,27IF9@186928|unclassified Lachnospiraceae	186801|Clostridia	F	DNA/RNA non-specific endonuclease	-	-	-	ko:K15051	-	-	-	-	ko00000	-	-	-	Ada_Zn_binding,Endonuclea_NS_2
NFNHFNFO_04655	658655.HMPREF0988_00556	1.63e-90	265.0	2EASV@1|root,334UU@2|Bacteria,1VEJX@1239|Firmicutes,24R23@186801|Clostridia,27P33@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04656	658088.HMPREF0987_01134	6.82e-66	200.0	292K7@1|root,2ZQ45@2|Bacteria,1W3HV@1239|Firmicutes,256NF@186801|Clostridia,27S8N@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04657	658088.HMPREF0987_01136	3.5e-81	240.0	COG2337@1|root,COG2337@2|Bacteria,1V6DK@1239|Firmicutes,24KXM@186801|Clostridia,27NI8@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Toxic component of a toxin-antitoxin (TA) module	-	-	-	-	-	-	-	-	-	-	-	-	PemK_toxin
NFNHFNFO_04658	658088.HMPREF0987_01137	4.1e-111	319.0	2DN5I@1|root,32VNS@2|Bacteria,1VA6J@1239|Firmicutes,24HYW@186801|Clostridia,27NM8@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04659	658088.HMPREF0987_01138	0.0	885.0	COG0553@1|root,COG0553@2|Bacteria,1TPFZ@1239|Firmicutes,248ZJ@186801|Clostridia,27J0X@186928|unclassified Lachnospiraceae	186801|Clostridia	KL	SNF2 family N-terminal domain	-	-	-	-	-	-	-	-	-	-	-	-	SNF2_N
NFNHFNFO_04660	658088.HMPREF0987_01139	2.7e-61	188.0	2E38J@1|root,32Y88@2|Bacteria,1VAXK@1239|Firmicutes,24N7K@186801|Clostridia,27NRC@186928|unclassified Lachnospiraceae	186801|Clostridia	S	VRR_NUC	-	-	-	-	-	-	-	-	-	-	-	-	VRR_NUC
NFNHFNFO_04661	658088.HMPREF0987_01140	0.0	1567.0	COG5545@1|root,COG5545@2|Bacteria,1TQNX@1239|Firmicutes,2495S@186801|Clostridia,27JNW@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Virulence-associated protein E	-	-	-	-	-	-	-	-	-	-	-	-	VirE
NFNHFNFO_04662	658655.HMPREF0988_00563	0.0	1260.0	COG0749@1|root,COG0749@2|Bacteria,1TPTJ@1239|Firmicutes,2487V@186801|Clostridia,27JEU@186928|unclassified Lachnospiraceae	186801|Clostridia	L	DNA polymerase A domain	-	-	2.7.7.7	ko:K02334	-	-	-	-	ko00000,ko01000	-	-	-	DNA_pol_A
NFNHFNFO_04663	658655.HMPREF0988_00564	3.47e-54	170.0	2BRMM@1|root,32KM1@2|Bacteria,1USAB@1239|Firmicutes,25A9M@186801|Clostridia,27PYJ@186928|unclassified Lachnospiraceae	186801|Clostridia	S	NUMOD4 motif	-	-	-	-	-	-	-	-	-	-	-	-	NUMOD4
NFNHFNFO_04664	658655.HMPREF0988_00565	1.81e-121	347.0	28J2E@1|root,2Z8YX@2|Bacteria,1TRF9@1239|Firmicutes,249U3@186801|Clostridia,27KN8@186928|unclassified Lachnospiraceae	186801|Clostridia	S	Protein of unknown function (DUF2815)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2815
NFNHFNFO_04665	658088.HMPREF0987_01144	1.66e-269	738.0	COG2887@1|root,COG2887@2|Bacteria,1TPIC@1239|Firmicutes,247TB@186801|Clostridia,27IAF@186928|unclassified Lachnospiraceae	186801|Clostridia	L	Protein of unknown function (DUF2800)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2800
NFNHFNFO_04666	658088.HMPREF0987_01145	1.15e-58	182.0	2E6I4@1|root,3315A@2|Bacteria,1VBDX@1239|Firmicutes,25HM7@186801|Clostridia,27PTN@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04667	658088.HMPREF0987_01146	3.55e-39	130.0	2FEN7@1|root,346MK@2|Bacteria,1W0Z7@1239|Firmicutes,254DY@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04668	658088.HMPREF0987_01147	1.42e-93	273.0	2CGYE@1|root,32T72@2|Bacteria,1VBA8@1239|Firmicutes,24K9V@186801|Clostridia,27PX4@186928|unclassified Lachnospiraceae	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04669	658088.HMPREF0987_01148	1.9e-70	213.0	COG2378@1|root,COG2378@2|Bacteria,1V7YK@1239|Firmicutes,24HGV@186801|Clostridia,27MX5@186928|unclassified Lachnospiraceae	186801|Clostridia	K	HTH domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_11
NFNHFNFO_04671	483218.BACPEC_01273	5.65e-50	170.0	295XU@1|root,2ZT8Q@2|Bacteria,1W5P1@1239|Firmicutes,254WY@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04672	483218.BACPEC_01272	1.25e-146	418.0	COG2856@1|root,COG2856@2|Bacteria,1V0QI@1239|Firmicutes,24IKA@186801|Clostridia,26BS7@186813|unclassified Clostridiales	186801|Clostridia	E	Pfam:DUF955	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M78
NFNHFNFO_04673	483218.BACPEC_01271	7.72e-77	230.0	COG1396@1|root,COG1396@2|Bacteria,1VG62@1239|Firmicutes,24NEA@186801|Clostridia,269WV@186813|unclassified Clostridiales	186801|Clostridia	K	Helix-turn-helix XRE-family like proteins	-	-	-	-	-	-	-	-	-	-	-	-	HTH_19,HTH_3,HTH_31
NFNHFNFO_04674	1034347.CAHJ01000005_gene2492	9.51e-195	556.0	COG0270@1|root,COG0270@2|Bacteria,1TSNX@1239|Firmicutes,4HFAI@91061|Bacilli,1ZBQM@1386|Bacillus	91061|Bacilli	L	DNA (cytosine-5-)-methyltransferase activity	ddeI	-	2.1.1.37	ko:K00558	ko00270,ko01100,ko05206,map00270,map01100,map05206	M00035	R04858	RC00003,RC00332	ko00000,ko00001,ko00002,ko01000,ko02048,ko03032,ko03036	-	-	-	DNA_methylase
NFNHFNFO_04675	643867.Ftrac_2142	9.09e-61	206.0	28MJP@1|root,2ZAW3@2|Bacteria,4NKRQ@976|Bacteroidetes,47TSU@768503|Cytophagia	976|Bacteroidetes	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04676	397287.C807_01439	9.13e-73	221.0	COG3727@1|root,COG3727@2|Bacteria,1V3S8@1239|Firmicutes,24MYE@186801|Clostridia,27MW1@186928|unclassified Lachnospiraceae	186801|Clostridia	L	May nick specific sequences that contain T G mispairs resulting from m5C-deamination	vsr	-	-	ko:K07458	-	-	-	-	ko00000,ko01000,ko03400	-	-	-	DUF559,Vsr
NFNHFNFO_04677	658655.HMPREF0988_00579	2.86e-36	126.0	2EEYC@1|root,338RR@2|Bacteria,1VJ7I@1239|Firmicutes,24SPS@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04678	476272.RUMHYD_02529	5.78e-18	79.7	COG0454@1|root,COG0456@2|Bacteria,1VBFC@1239|Firmicutes,24KAJ@186801|Clostridia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	bltD	-	2.3.1.57	ko:K00657	ko00330,ko01100,ko04216,map00330,map01100,map04216	M00135	R01154	RC00004,RC00096	ko00000,ko00001,ko00002,ko01000	-	-	-	Acetyltransf_1
NFNHFNFO_04679	33035.JPJF01000013_gene4599	1.44e-140	398.0	COG0454@1|root,COG0456@2|Bacteria,1V1TW@1239|Firmicutes,24HI4@186801|Clostridia,3Y026@572511|Blautia	186801|Clostridia	K	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
NFNHFNFO_04680	33035.JPJF01000013_gene4600	3.88e-163	458.0	COG0789@1|root,COG0789@2|Bacteria,1TS6Z@1239|Firmicutes,24BUT@186801|Clostridia,3Y0EV@572511|Blautia	186801|Clostridia	K	TipAS antibiotic-recognition domain	-	-	-	-	-	-	-	-	-	-	-	-	MerR_1,TipAS
NFNHFNFO_04681	33035.JPJF01000013_gene4601	1.99e-284	781.0	COG2211@1|root,COG2211@2|Bacteria,1V65Z@1239|Firmicutes,24ISG@186801|Clostridia	186801|Clostridia	G	MFS/sugar transport protein	-	-	-	-	-	-	-	-	-	-	-	-	MFS_2
NFNHFNFO_04682	33035.JPJF01000013_gene4603	2.75e-217	600.0	COG0191@1|root,COG0191@2|Bacteria,1TQ01@1239|Firmicutes,248B7@186801|Clostridia,3XZPJ@572511|Blautia	186801|Clostridia	G	COG COG0191 Fructose tagatose bisphosphate aldolase	fba	-	4.1.2.13	ko:K01624	ko00010,ko00030,ko00051,ko00680,ko00710,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00010,map00030,map00051,map00680,map00710,map01100,map01110,map01120,map01130,map01200,map01230	M00001,M00003,M00165,M00167,M00344,M00345	R01068,R01070,R01829,R02568	RC00438,RC00439,RC00603,RC00604	ko00000,ko00001,ko00002,ko01000	-	-	-	F_bP_aldolase
NFNHFNFO_04683	33035.JPJF01000013_gene4605	1.67e-39	134.0	COG0698@1|root,COG0698@2|Bacteria,1V3HE@1239|Firmicutes,24JWT@186801|Clostridia,3XZXS@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	rpiB	-	-	-	-	-	-	-	-	-	-	-	LacAB_rpiB
NFNHFNFO_04684	33035.JPJF01000013_gene4606	2.76e-162	455.0	COG2186@1|root,COG2186@2|Bacteria,1V3VZ@1239|Firmicutes,25MUE@186801|Clostridia,3Y1KV@572511|Blautia	186801|Clostridia	K	FCD domain	-	-	-	-	-	-	-	-	-	-	-	-	FCD,GntR
NFNHFNFO_04685	33035.JPJF01000013_gene4607	9.61e-168	470.0	COG1028@1|root,COG1028@2|Bacteria,1TP76@1239|Firmicutes,247PV@186801|Clostridia,3XYM7@572511|Blautia	186801|Clostridia	IQ	Psort location Cytoplasmic, score	-	-	1.1.1.100	ko:K00059	ko00061,ko00333,ko00780,ko01040,ko01100,ko01130,ko01212,map00061,map00333,map00780,map01040,map01100,map01130,map01212	M00083,M00572	R04533,R04534,R04536,R04543,R04566,R04953,R04964,R07759,R07763,R10116,R10120,R11671	RC00029,RC00117	ko00000,ko00001,ko00002,ko01000,ko01004	-	-	-	adh_short,adh_short_C2
NFNHFNFO_04686	33035.JPJF01000013_gene4608	1.58e-215	596.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,3Y108@572511|Blautia	186801|Clostridia	G	Transketolase, pyrimidine binding domain	-	-	-	-	-	-	-	-	-	-	-	-	Transket_pyr,Transketolase_C
NFNHFNFO_04687	33035.JPJF01000013_gene4609	2.34e-205	568.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3Y1BE@572511|Blautia	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
NFNHFNFO_04688	33035.JPJF01000013_gene4610	7.15e-267	735.0	COG1593@1|root,COG1593@2|Bacteria,1TPNU@1239|Firmicutes,248BY@186801|Clostridia,3XZAD@572511|Blautia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 9.99	-	-	-	-	-	-	-	-	-	-	-	-	DctM
NFNHFNFO_04689	33035.JPJF01000013_gene4611	1.61e-102	297.0	COG3090@1|root,COG3090@2|Bacteria,1V6P9@1239|Firmicutes,24JKS@186801|Clostridia,3XZTR@572511|Blautia	186801|Clostridia	G	Tripartite ATP-independent periplasmic transporters, DctQ component	-	-	-	-	-	-	-	-	-	-	-	-	DctQ
NFNHFNFO_04690	33035.JPJF01000013_gene4612	2.62e-231	639.0	COG1638@1|root,COG1638@2|Bacteria,1UCYF@1239|Firmicutes,25B11@186801|Clostridia,3Y2DS@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein, family 7	-	-	-	-	-	-	-	-	-	-	-	-	DctP
NFNHFNFO_04691	33035.JPJF01000013_gene4613	6.68e-94	280.0	COG5660@1|root,COG5660@2|Bacteria,1VKXY@1239|Firmicutes,24UK9@186801|Clostridia,3Y0RV@572511|Blautia	186801|Clostridia	S	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	zf-HC2
NFNHFNFO_04692	33035.JPJF01000013_gene4614	1.12e-99	290.0	COG1595@1|root,COG1595@2|Bacteria,1V8GV@1239|Firmicutes,25B12@186801|Clostridia	186801|Clostridia	K	Belongs to the sigma-70 factor family. ECF subfamily	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_04693	33035.JPJF01000013_gene4615	0.0	1388.0	COG0577@1|root,COG0577@2|Bacteria,1V0HA@1239|Firmicutes,24AID@186801|Clostridia,3XYH2@572511|Blautia	186801|Clostridia	V	COG COG0577 ABC-type antimicrobial peptide transport system, permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
NFNHFNFO_04694	33035.JPJF01000013_gene4616	2.62e-144	410.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,24BG4@186801|Clostridia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_04695	33035.JPJF01000013_gene4617	8.13e-190	532.0	COG0642@1|root,COG2205@2|Bacteria,1TR7T@1239|Firmicutes,25B13@186801|Clostridia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_04696	33035.JPJF01000013_gene4618	4.09e-145	410.0	COG0745@1|root,COG0745@2|Bacteria,1V0KW@1239|Firmicutes,24E9Z@186801|Clostridia,3Y066@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_04697	33035.JPJF01000013_gene4619	5.13e-279	769.0	COG0642@1|root,COG2205@2|Bacteria,1TRAB@1239|Firmicutes,24DV3@186801|Clostridia,3Y1EV@572511|Blautia	186801|Clostridia	T	Domain of unknown function (DUF4173)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4173
NFNHFNFO_04698	33035.JPJF01000013_gene4620	5.49e-38	127.0	COG3655@1|root,COG3655@2|Bacteria,1VESP@1239|Firmicutes,24QSQ@186801|Clostridia,3Y0N1@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K07727	-	-	-	-	ko00000,ko03000	-	-	-	HTH_26
NFNHFNFO_04699	33035.JPJF01000013_gene4621	1.15e-99	290.0	2AKH0@1|root,31B8X@2|Bacteria,1V6ZY@1239|Firmicutes,24JGF@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF2975)	-	-	-	-	-	-	-	-	-	-	-	-	DUF2975
NFNHFNFO_04701	33035.JPJF01000013_gene4622	3.64e-104	304.0	COG1247@1|root,COG1247@2|Bacteria,1V3XH@1239|Firmicutes,24HCN@186801|Clostridia,3Y0EN@572511|Blautia	186801|Clostridia	M	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1
NFNHFNFO_04702	33035.JPJF01000013_gene4623	2.26e-105	318.0	COG3064@1|root,COG3064@2|Bacteria	2|Bacteria	M	translation initiation factor activity	cbpA	-	-	ko:K03646	-	-	-	-	ko00000,ko02000	2.C.1.2	-	-	CW_binding_1,RICH,SNase,YSIRK_signal
NFNHFNFO_04703	33035.JPJF01000013_gene4624	4.83e-102	296.0	COG1329@1|root,COG1329@2|Bacteria,1VAA0@1239|Firmicutes,24P60@186801|Clostridia,3Y0SQ@572511|Blautia	186801|Clostridia	K	CarD-like/TRCF domain	-	-	-	ko:K07736	-	-	-	-	ko00000,ko03000	-	-	-	CarD_CdnL_TRCF
NFNHFNFO_04704	1232449.BAHV02000010_gene2812	2.49e-81	247.0	COG1102@1|root,COG1102@2|Bacteria,1TRCW@1239|Firmicutes,249VD@186801|Clostridia	186801|Clostridia	F	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NFNHFNFO_04705	545697.HMPREF0216_02461	1.76e-215	609.0	COG0534@1|root,COG0534@2|Bacteria,1TP5P@1239|Firmicutes,247PQ@186801|Clostridia,36VMU@31979|Clostridiaceae	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_04706	33035.JPJF01000013_gene4625	1.68e-275	751.0	COG0407@1|root,COG0407@2|Bacteria,1VQWJ@1239|Firmicutes,24YE8@186801|Clostridia	186801|Clostridia	H	Uroporphyrinogen decarboxylase (URO-D)	-	-	-	-	-	-	-	-	-	-	-	-	URO-D
NFNHFNFO_04707	33035.JPJF01000013_gene4626	2.58e-211	587.0	COG1609@1|root,COG1609@2|Bacteria,1TPZJ@1239|Firmicutes,248K0@186801|Clostridia,3Y29Y@572511|Blautia	186801|Clostridia	K	helix_turn _helix lactose operon repressor	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_04708	33035.JPJF01000013_gene4627	3e-176	495.0	COG0697@1|root,COG0697@2|Bacteria,1TPUW@1239|Firmicutes,247X1@186801|Clostridia,3XZ7M@572511|Blautia	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_04709	33035.JPJF01000013_gene4628	5.6e-230	635.0	COG1363@1|root,COG1363@2|Bacteria,1TS74@1239|Firmicutes,25CDG@186801|Clostridia	186801|Clostridia	G	M42 glutamyl aminopeptidase	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M42
NFNHFNFO_04710	33035.JPJF01000013_gene4629	1.65e-304	833.0	COG0534@1|root,COG0534@2|Bacteria,1TQMT@1239|Firmicutes,249WJ@186801|Clostridia	186801|Clostridia	V	Mate efflux family protein	-	-	-	-	-	-	-	-	-	-	-	-	MatE
NFNHFNFO_04711	33035.JPJF01000013_gene4630	1.65e-303	828.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia,3XZJC@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_04712	33035.JPJF01000013_gene4631	2.58e-190	529.0	COG0395@1|root,COG0395@2|Bacteria,1TRCP@1239|Firmicutes,249NY@186801|Clostridia,3Y0FC@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02026	-	M00207	-	-	ko00000,ko00002,ko02000	3.A.1.1	-	-	BPD_transp_1
NFNHFNFO_04713	33035.JPJF01000013_gene4632	5.3e-208	575.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia,3XYXH@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10189	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	BPD_transp_1
NFNHFNFO_04714	33035.JPJF01000013_gene4633	0.0	1902.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3XYIU@572511|Blautia	186801|Clostridia	G	Beta galactosidase small chain	-	-	-	-	-	-	-	-	-	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFNHFNFO_04715	33035.JPJF01000013_gene4634	1.19e-233	644.0	COG1609@1|root,COG1609@2|Bacteria,1UK1H@1239|Firmicutes,249XN@186801|Clostridia,3XZFY@572511|Blautia	1239|Firmicutes	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_04716	33035.JPJF01000013_gene4635	1.02e-221	613.0	COG2222@1|root,COG2222@2|Bacteria,1VQYP@1239|Firmicutes,24YUI@186801|Clostridia	186801|Clostridia	M	SIS domain	-	-	-	-	-	-	-	-	-	-	-	-	SIS
NFNHFNFO_04717	33035.JPJF01000013_gene4636	7.34e-116	336.0	COG2188@1|root,COG2188@2|Bacteria	2|Bacteria	K	DNA-binding transcription factor activity	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
NFNHFNFO_04718	33035.JPJF01000013_gene4637	8.5e-170	476.0	COG0524@1|root,COG0524@2|Bacteria,1TSA3@1239|Firmicutes,24CDF@186801|Clostridia,3Y0FA@572511|Blautia	186801|Clostridia	G	COG COG0524 Sugar kinases, ribokinase family	-	-	2.7.1.218	ko:K10710	-	-	R08124	RC00002,RC00017	ko00000,ko01000	-	-	-	PfkB
NFNHFNFO_04719	33035.JPJF01000013_gene4638	1.75e-109	321.0	COG2188@1|root,COG2188@2|Bacteria,1UYBW@1239|Firmicutes,24N1N@186801|Clostridia,3Y0MI@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 8.87	-	-	-	ko:K03710	-	-	-	-	ko00000,ko03000	-	-	-	GntR,UTRA
NFNHFNFO_04721	33035.JPJF01000073_gene4420	4.86e-63	195.0	2EF6F@1|root,338ZI@2|Bacteria,1VI9H@1239|Firmicutes,24PYC@186801|Clostridia	186801|Clostridia	S	Bacterial PH domain	-	-	-	-	-	-	-	-	-	-	-	-	bPH_4
NFNHFNFO_04722	33035.JPJF01000073_gene4421	2.51e-100	294.0	COG1595@1|root,COG1595@2|Bacteria,1VH54@1239|Firmicutes,25MQV@186801|Clostridia,3Y22P@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	-	-	-	-	-	-	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_04724	1232453.BAIF02000084_gene386	1.49e-153	437.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,26A14@186813|unclassified Clostridiales	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	-	-	-	-	-	-	-	-	-	ABC_tran
NFNHFNFO_04725	1232453.BAIF02000084_gene387	1.49e-144	421.0	2BZQD@1|root,2Z7JR@2|Bacteria,1UZDH@1239|Firmicutes,248UH@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2
NFNHFNFO_04726	1232453.BAIF02000084_gene388	2.19e-176	503.0	2DBN9@1|root,2ZA33@2|Bacteria,1U6HI@1239|Firmicutes,24G5F@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04727	33035.JPJF01000073_gene4423	3.76e-267	733.0	COG2230@1|root,COG2230@2|Bacteria,1TSG4@1239|Firmicutes,248GV@186801|Clostridia,3XZP3@572511|Blautia	186801|Clostridia	M	Mycolic acid cyclopropane synthetase	cfa	-	2.1.1.79	ko:K00574	-	-	-	-	ko00000,ko01000	-	-	-	CMAS
NFNHFNFO_04728	33035.JPJF01000073_gene4425	0.0	1902.0	COG1361@1|root,COG3386@1|root,COG1361@2|Bacteria,COG3386@2|Bacteria,1UQ5B@1239|Firmicutes,24AUI@186801|Clostridia	186801|Clostridia	M	Domain of unknown function DUF11	-	-	-	-	-	-	-	-	-	-	-	-	DUF11,DUF3794,SdrD_B
NFNHFNFO_04729	33035.JPJF01000073_gene4426	7.75e-145	410.0	COG1131@1|root,COG1131@2|Bacteria,1TRTC@1239|Firmicutes,2488R@186801|Clostridia	186801|Clostridia	V	abc transporter atp-binding protein	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_04730	33035.JPJF01000073_gene4427	0.0	927.0	28IHZ@1|root,2Z8J5@2|Bacteria,1TQV6@1239|Firmicutes,249TE@186801|Clostridia,3Y0MJ@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04731	33035.JPJF01000073_gene4432	7.25e-124	356.0	COG4832@1|root,COG4832@2|Bacteria,1TQC2@1239|Firmicutes,248YH@186801|Clostridia,3Y1ZD@572511|Blautia	186801|Clostridia	S	GyrI-like small molecule binding domain	-	-	-	-	-	-	-	-	-	-	-	-	GyrI-like
NFNHFNFO_04732	33035.JPJF01000073_gene4433	2.28e-102	297.0	COG3695@1|root,COG3695@2|Bacteria,1TPJI@1239|Firmicutes,249H6@186801|Clostridia,3XZ1A@572511|Blautia	186801|Clostridia	L	6-O-methylguanine DNA methyltransferase, DNA binding domain	-	-	-	-	-	-	-	-	-	-	-	-	DNA_binding_1
NFNHFNFO_04733	556261.HMPREF0240_02934	1.37e-141	402.0	COG1136@1|root,COG1136@2|Bacteria,1TP6H@1239|Firmicutes,247JJ@186801|Clostridia,36EH8@31979|Clostridiaceae	186801|Clostridia	V	ABC transporter, ATP-binding protein	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_04734	180332.JTGN01000006_gene3279	0.0	1161.0	COG0577@1|root,COG0577@2|Bacteria,1TRAS@1239|Firmicutes,248SQ@186801|Clostridia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K02004	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	FtsX,MacB_PCD
NFNHFNFO_04735	33035.JPJF01000073_gene4434	6.64e-110	318.0	COG0640@1|root,COG0640@2|Bacteria,1TX6K@1239|Firmicutes,25IRQ@186801|Clostridia,3Y26I@572511|Blautia	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_20
NFNHFNFO_04736	33035.JPJF01000073_gene4435	1.09e-162	456.0	COG1131@1|root,COG1131@2|Bacteria,1TPMQ@1239|Firmicutes,248QD@186801|Clostridia	186801|Clostridia	V	Abc transporter	-	-	-	ko:K01990,ko:K19340	ko02010,map02010	M00254,M00762	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.132.2	-	-	ABC_tran
NFNHFNFO_04737	33035.JPJF01000073_gene4436	0.0	877.0	COG2898@1|root,COG2898@2|Bacteria,1U5FR@1239|Firmicutes,248XI@186801|Clostridia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01992	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran_2
NFNHFNFO_04738	33035.JPJF01000073_gene4437	1.48e-159	448.0	COG4200@1|root,COG4200@2|Bacteria,1TSD5@1239|Firmicutes,24DU9@186801|Clostridia,3Y1WR@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score	-	-	-	ko:K20461	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
NFNHFNFO_04739	33035.JPJF01000073_gene4438	7.31e-154	435.0	COG4200@1|root,COG4200@2|Bacteria,1V273@1239|Firmicutes,24HVF@186801|Clostridia	186801|Clostridia	S	ABC-2 family transporter protein	-	-	-	ko:K20460	ko02010,map02010	M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC2_membrane_4
NFNHFNFO_04740	33035.JPJF01000073_gene4439	4.44e-199	553.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,3Y1FM@572511|Blautia	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	bcrA_2	-	-	ko:K01990,ko:K20459	ko02010,map02010	M00254,M00813	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.3,3.A.1.124.4,3.A.1.124.5	-	-	ABC_tran
NFNHFNFO_04741	33035.JPJF01000073_gene4440	1.32e-145	412.0	COG0745@1|root,COG0745@2|Bacteria,1TYPK@1239|Firmicutes,247Y9@186801|Clostridia,3Y1K4@572511|Blautia	186801|Clostridia	T	Transcriptional regulatory protein, C terminal	-	-	-	-	-	-	-	-	-	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_04742	33035.JPJF01000073_gene4441	5.6e-263	728.0	COG0642@1|root,COG2205@2|Bacteria,1TS12@1239|Firmicutes,24AAW@186801|Clostridia,3Y1EW@572511|Blautia	186801|Clostridia	T	His Kinase A (phosphoacceptor) domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c,HisKA
NFNHFNFO_04743	1196323.ALKF01000195_gene2022	3.15e-49	174.0	COG3173@1|root,COG3173@2|Bacteria,1U6NE@1239|Firmicutes,4IRID@91061|Bacilli,26WCY@186822|Paenibacillaceae	91061|Bacilli	S	Fructosamine kinase	-	-	-	-	-	-	-	-	-	-	-	-	APH
NFNHFNFO_04744	33035.JPJF01000045_gene1054	3.98e-194	540.0	COG0583@1|root,COG0583@2|Bacteria,1TP3E@1239|Firmicutes,248HI@186801|Clostridia,3Y07S@572511|Blautia	186801|Clostridia	K	LysR substrate binding domain	cpsY	-	-	-	-	-	-	-	-	-	-	-	HTH_1,LysR_substrate
NFNHFNFO_04745	33035.JPJF01000045_gene1053	0.0	986.0	COG1292@1|root,COG1292@2|Bacteria,1TRS6@1239|Firmicutes,2482K@186801|Clostridia	186801|Clostridia	M	Belongs to the BCCT transporter (TC 2.A.15) family	-	-	-	-	-	-	-	-	-	-	-	-	BCCT
NFNHFNFO_04746	33035.JPJF01000045_gene1052	0.0	867.0	COG1679@1|root,COG1679@2|Bacteria,1UJDG@1239|Firmicutes,24DTH@186801|Clostridia	186801|Clostridia	S	Protein of unknown function (DUF521)	-	-	-	ko:K09123	-	-	-	-	ko00000	-	-	-	DUF521
NFNHFNFO_04747	33035.JPJF01000045_gene1051	8.4e-93	271.0	COG1786@1|root,COG1786@2|Bacteria,1V9ZT@1239|Firmicutes,24N2I@186801|Clostridia	186801|Clostridia	S	Protein of unknown function DUF126	-	-	-	ko:K09128	-	-	-	-	ko00000	-	-	-	DUF126
NFNHFNFO_04748	33035.JPJF01000045_gene1050	2.2e-140	399.0	COG2738@1|root,COG2738@2|Bacteria,1TPD3@1239|Firmicutes,2490Y@186801|Clostridia,3XZPM@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.26	yugP	-	-	ko:K06973	-	-	-	-	ko00000	-	-	-	Zn_peptidase_2
NFNHFNFO_04749	33035.JPJF01000045_gene1049	4.74e-283	776.0	COG2207@1|root,COG4936@1|root,COG2207@2|Bacteria,COG4936@2|Bacteria,1U23Q@1239|Firmicutes,24CZ9@186801|Clostridia	186801|Clostridia	K	Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	HTH_18,HTH_AraC,PocR
NFNHFNFO_04750	33035.JPJF01000045_gene1048	9.36e-143	404.0	COG5012@1|root,COG5012@2|Bacteria,1V55S@1239|Firmicutes,24HXM@186801|Clostridia	186801|Clostridia	S	cobalamin binding protein	-	-	-	-	-	-	-	-	-	-	-	-	B12-binding,B12-binding_2
NFNHFNFO_04751	33035.JPJF01000045_gene1047	0.0	924.0	COG5598@1|root,COG5598@2|Bacteria,1UZPX@1239|Firmicutes,24FC6@186801|Clostridia	186801|Clostridia	H	Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
NFNHFNFO_04752	33035.JPJF01000045_gene1046	9.7e-184	514.0	COG0697@1|root,COG0697@2|Bacteria,1VJPP@1239|Firmicutes,24SJ6@186801|Clostridia	186801|Clostridia	EG	EamA-like transporter family	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_04753	33035.JPJF01000045_gene1045	1.85e-147	418.0	COG1414@1|root,COG1414@2|Bacteria,1TRMW@1239|Firmicutes,24BQA@186801|Clostridia	186801|Clostridia	K	transcriptional regulator	-	-	-	-	-	-	-	-	-	-	-	-	HTH_IclR,IclR
NFNHFNFO_04754	33035.JPJF01000045_gene1044	0.0	899.0	COG5598@1|root,COG5598@2|Bacteria,1V15E@1239|Firmicutes,24CMY@186801|Clostridia	2|Bacteria	H	PFAM Trimethylamine methyltransferase (MTTB)	-	-	2.1.1.250	ko:K14083	ko00680,ko01120,ko01200,map00680,map01120,map01200	M00563	R09124,R10016	RC00035,RC00732,RC01144,RC02984	ko00000,ko00001,ko00002,ko01000	-	-	-	MTTB
NFNHFNFO_04755	33035.JPJF01000045_gene1043	1.58e-41	136.0	COG2221@1|root,COG2221@2|Bacteria	2|Bacteria	C	Nitrite and sulphite reductase 4Fe-4S	-	-	1.2.7.3	ko:K00176	ko00020,ko00720,ko01100,ko01120,ko01200,map00020,map00720,map01100,map01120,map01200	M00009,M00011,M00173,M00620	R01197	RC00004,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	Fer4,Fer4_6
NFNHFNFO_04756	33035.JPJF01000045_gene1042	4.29e-249	684.0	COG0674@1|root,COG0674@2|Bacteria,1TSSC@1239|Firmicutes,248I6@186801|Clostridia	186801|Clostridia	C	PFAM Pyruvate flavodoxin ferredoxin oxidoreductase	-	-	1.2.7.11,1.2.7.3	ko:K00174	ko00010,ko00020,ko00620,ko00650,ko00720,ko01100,ko01120,ko01130,ko01200,map00010,map00020,map00620,map00650,map00720,map01100,map01120,map01130,map01200	M00009,M00011,M00173,M00620	R01196,R01197	RC00004,RC02742,RC02833	br01601,ko00000,ko00001,ko00002,ko01000	-	-	-	PFOR_II,POR_N
NFNHFNFO_04757	33035.JPJF01000045_gene1041	1.8e-183	509.0	COG1013@1|root,COG1013@2|Bacteria,1UNVM@1239|Firmicutes,25CAM@186801|Clostridia	186801|Clostridia	C	Thiamine pyrophosphate enzyme, C-terminal TPP binding domain	-	-	-	-	-	-	-	-	-	-	-	-	TPP_enzyme_C
NFNHFNFO_04758	33035.JPJF01000045_gene1040	4.61e-114	328.0	COG1014@1|root,COG1014@2|Bacteria,1V3QA@1239|Firmicutes,24INU@186801|Clostridia	186801|Clostridia	C	Pyruvate ferredoxin/flavodoxin oxidoreductase	-	-	-	-	-	-	-	-	-	-	-	-	POR
NFNHFNFO_04759	33035.JPJF01000045_gene1039	0.0	1235.0	COG0045@1|root,COG1042@1|root,COG0045@2|Bacteria,COG1042@2|Bacteria,1TPTQ@1239|Firmicutes,249CX@186801|Clostridia,3Y0Z1@572511|Blautia	186801|Clostridia	C	Succinyl-CoA ligase like flavodoxin domain	-	-	6.2.1.13	ko:K01905,ko:K22224	ko00010,ko00620,ko00640,ko01100,ko01120,map00010,map00620,map00640,map01100,map01120	-	R00229,R00920	RC00004,RC00012,RC00014	ko00000,ko00001,ko01000,ko01004	-	-	-	ATP-grasp_5,CoA_binding_2,Succ_CoA_lig
NFNHFNFO_04760	33035.JPJF01000045_gene1038	1.7e-79	236.0	COG0251@1|root,COG0251@2|Bacteria,1V6HG@1239|Firmicutes,25035@186801|Clostridia	186801|Clostridia	J	Endoribonuclease L-PSP	-	-	3.5.99.10	ko:K09022	-	-	R11098,R11099	RC03275,RC03354	ko00000,ko01000	-	-	-	Ribonuc_L-PSP
NFNHFNFO_04761	33035.JPJF01000045_gene1037	2.76e-286	783.0	COG1228@1|root,COG1228@2|Bacteria,1TQQ0@1239|Firmicutes,24EHA@186801|Clostridia	186801|Clostridia	Q	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	Amidohydro_1
NFNHFNFO_04762	33035.JPJF01000045_gene1024	3.72e-233	650.0	COG3290@1|root,COG3290@2|Bacteria,1V48N@1239|Firmicutes,24CD0@186801|Clostridia,3Y0IS@572511|Blautia	186801|Clostridia	T	GHKL domain	-	-	-	-	-	-	-	-	-	-	-	-	HATPase_c_5,SPOB_a
NFNHFNFO_04763	33035.JPJF01000045_gene1022	6.37e-143	405.0	COG3279@1|root,COG3279@2|Bacteria,1V3QY@1239|Firmicutes,24IT9@186801|Clostridia,3Y1IK@572511|Blautia	186801|Clostridia	KT	LytTr DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	LytTR,Response_reg
NFNHFNFO_04764	658086.HMPREF0994_07268	1.64e-69	240.0	COG4219@1|root,COG5184@1|root,COG4219@2|Bacteria,COG5184@2|Bacteria,1TP3Z@1239|Firmicutes,24A30@186801|Clostridia,27R8K@186928|unclassified Lachnospiraceae	186801|Clostridia	DKTZ	BlaR1 peptidase M56	-	-	-	-	-	-	-	-	-	-	-	-	Peptidase_M56
NFNHFNFO_04765	457421.CBFG_03122	1.38e-119	345.0	COG1309@1|root,COG1309@2|Bacteria,1TPXF@1239|Firmicutes,24F9Q@186801|Clostridia	186801|Clostridia	K	transcriptional regulator, TetR family	-	-	-	-	-	-	-	-	-	-	-	-	TetR_N
NFNHFNFO_04766	457421.CBFG_03121	2.8e-221	619.0	COG0477@1|root,COG2814@2|Bacteria,1UZPE@1239|Firmicutes,2490R@186801|Clostridia,26CRS@186813|unclassified Clostridiales	186801|Clostridia	EGP	Transmembrane secretion effector	-	-	-	-	-	-	-	-	-	-	-	-	MFS_1,MFS_3
NFNHFNFO_04767	457421.CBFG_03120	0.0	1150.0	COG0577@1|root,COG0577@2|Bacteria,1TQ3S@1239|Firmicutes,248TI@186801|Clostridia	186801|Clostridia	V	ABC-type transport system involved in lipoprotein release permease component	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
NFNHFNFO_04768	457421.CBFG_03119	1.11e-134	386.0	COG1136@1|root,COG1136@2|Bacteria,1TQU8@1239|Firmicutes,24AM8@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_04769	33035.JPJF01000098_gene1782	3.77e-284	779.0	COG1879@1|root,COG1879@2|Bacteria,1TT3I@1239|Firmicutes,247SI@186801|Clostridia,3XZQM@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	mglB	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
NFNHFNFO_04770	33035.JPJF01000098_gene1781	0.0	972.0	COG1129@1|root,COG1129@2|Bacteria,1TP6I@1239|Firmicutes,247II@186801|Clostridia,3XZ1W@572511|Blautia	186801|Clostridia	P	import. Responsible for energy coupling to the transport system	mglA	-	3.6.3.17	ko:K10542	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko01000,ko02000	3.A.1.2.3	-	-	ABC_tran
NFNHFNFO_04771	33035.JPJF01000098_gene1780	0.0	984.0	COG3064@1|root,COG4211@1|root,COG3064@2|Bacteria,COG4211@2|Bacteria,1UI1K@1239|Firmicutes,25EAQ@186801|Clostridia,3XZJQ@572511|Blautia	186801|Clostridia	G	Branched-chain amino acid transport system / permease component	-	-	-	ko:K10541	ko02010,map02010	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	BPD_transp_2
NFNHFNFO_04772	33035.JPJF01000098_gene1779	0.0	984.0	COG2207@1|root,COG4753@1|root,COG2207@2|Bacteria,COG4753@2|Bacteria,1TQCS@1239|Firmicutes,248SC@186801|Clostridia,3XZ1E@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K07720	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	HTH_18,HTH_AraC,Response_reg
NFNHFNFO_04773	33035.JPJF01000098_gene1778	0.0	1133.0	COG2972@1|root,COG2972@2|Bacteria,1TPVR@1239|Firmicutes,247XB@186801|Clostridia,3XZ6E@572511|Blautia	186801|Clostridia	T	ATPase histidine kinase DNA gyrase B HSP90 domain protein	-	-	2.7.13.3	ko:K07718	ko02020,map02020	M00519	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HAMP,HATPase_c,His_kinase,dCache_1
NFNHFNFO_04774	33035.JPJF01000098_gene1777	3.85e-187	525.0	COG1879@1|root,COG1879@2|Bacteria,1UD4W@1239|Firmicutes,24AYQ@186801|Clostridia,3XZS6@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10439	ko02010,ko02030,map02010,map02030	M00212	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.1,3.A.1.2.13,3.A.1.2.19	-	-	Peripla_BP_4
NFNHFNFO_04775	33035.JPJF01000098_gene1776	3.38e-218	605.0	COG1879@1|root,COG1879@2|Bacteria,1TQW5@1239|Firmicutes,249PS@186801|Clostridia,3XZ2X@572511|Blautia	186801|Clostridia	G	Periplasmic binding protein domain	-	-	-	ko:K10540	ko02010,ko02030,map02010,map02030	M00214	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.2.3	-	-	Peripla_BP_4
NFNHFNFO_04776	33035.JPJF01000098_gene1775	2.9e-171	478.0	COG1136@1|root,COG1136@2|Bacteria,1TNZG@1239|Firmicutes,247JX@186801|Clostridia,3Y191@572511|Blautia	186801|Clostridia	V	ATPases associated with a variety of cellular activities	-	-	-	ko:K02003	-	M00258	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_04777	33035.JPJF01000098_gene1774	0.0	1061.0	COG0577@1|root,COG0577@2|Bacteria,1TSMB@1239|Firmicutes,24ABI@186801|Clostridia,3Y1FY@572511|Blautia	186801|Clostridia	V	FtsX-like permease family	-	-	-	-	-	-	-	-	-	-	-	-	FtsX
NFNHFNFO_04778	1158607.UAU_02140	9.43e-183	526.0	COG2211@1|root,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,4HJPK@91061|Bacilli,4B6PF@81852|Enterococcaceae	91061|Bacilli	G	Vacuole effluxer Atg22 like	-	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	MFS_2
NFNHFNFO_04779	556261.HMPREF0240_01647	9.87e-138	397.0	COG2207@1|root,COG2207@2|Bacteria,1V0Z0@1239|Firmicutes,24BNN@186801|Clostridia,36I3B@31979|Clostridiaceae	186801|Clostridia	K	PFAM helix-turn-helix- domain containing protein, AraC type	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18,HTH_AraC
NFNHFNFO_04780	33035.JPJF01000098_gene1767	2.77e-228	630.0	COG1609@1|root,COG1609@2|Bacteria,1TSRM@1239|Firmicutes,24BFS@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_4
NFNHFNFO_04781	33035.JPJF01000098_gene1766	9.54e-241	661.0	COG0673@1|root,COG0673@2|Bacteria,1TRHA@1239|Firmicutes,24CRQ@186801|Clostridia	186801|Clostridia	S	Involved in the oxidation of myo-inositol (MI) and D- chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively	iolG	-	-	-	-	-	-	-	-	-	-	-	GFO_IDH_MocA,GFO_IDH_MocA_C
NFNHFNFO_04782	33035.JPJF01000098_gene1765	6.15e-202	559.0	COG1082@1|root,COG1082@2|Bacteria,1TS20@1239|Firmicutes,24E7U@186801|Clostridia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	5.3.99.11	ko:K06606	ko00562,ko01120,map00562,map01120	-	R09952	RC01513	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
NFNHFNFO_04783	33035.JPJF01000098_gene1764	0.0	1325.0	COG1102@1|root,COG2211@1|root,COG1102@2|Bacteria,COG2211@2|Bacteria,1TRA5@1239|Firmicutes,24ABB@186801|Clostridia	186801|Clostridia	G	Psort location CytoplasmicMembrane, score 10.00	gph	-	-	ko:K03292	-	-	-	-	ko00000	2.A.2	-	-	Cytidylate_kin2,MFS_2
NFNHFNFO_04784	33035.JPJF01000098_gene1763	2.08e-208	577.0	COG1082@1|root,COG1082@2|Bacteria,1TPZ2@1239|Firmicutes,24AF7@186801|Clostridia	186801|Clostridia	G	Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6 3,5-pentahydroxycyclohexanone) to 3D- (3,5 4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol)	iolE	-	4.2.1.44	ko:K03335	ko00562,ko01100,ko01120,map00562,map01100,map01120	-	R02782,R05659	RC00782,RC01448	ko00000,ko00001,ko01000	-	-	-	AP_endonuc_2
NFNHFNFO_04785	33035.JPJF01000098_gene1762	5.2e-226	622.0	COG1082@1|root,COG1082@2|Bacteria,1UZXE@1239|Firmicutes,24ECM@186801|Clostridia	186801|Clostridia	G	Xylose isomerase-like TIM barrel	-	-	-	-	-	-	-	-	-	-	-	-	AP_endonuc_2
NFNHFNFO_04786	33035.JPJF01000004_gene2018	1.74e-112	332.0	COG4942@1|root,COG4942@2|Bacteria	2|Bacteria	D	peptidase	-	-	2.1.1.72	ko:K03427	-	-	-	-	ko00000,ko01000,ko02048	-	-	-	PDDEXK_2
NFNHFNFO_04787	33035.JPJF01000083_gene5161	6.21e-95	279.0	COG1595@1|root,COG1595@2|Bacteria,1VBJI@1239|Firmicutes,24NKR@186801|Clostridia,3Y1WC@572511|Blautia	186801|Clostridia	K	Sigma-70, region 4	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_04788	33035.JPJF01000083_gene5160	1.45e-138	397.0	2CJ98@1|root,326JR@2|Bacteria,1V6ZE@1239|Firmicutes,25DE6@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04789	33035.JPJF01000083_gene5159	5.32e-185	517.0	COG1131@1|root,COG1131@2|Bacteria,1TRJH@1239|Firmicutes,247XQ@186801|Clostridia,3XZE4@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score	-	-	-	ko:K01990	-	M00254	-	-	ko00000,ko00002,ko02000	3.A.1	-	-	ABC_tran
NFNHFNFO_04790	33035.JPJF01000083_gene5158	2.21e-250	692.0	COG1277@1|root,COG1277@2|Bacteria,1UTUG@1239|Firmicutes,25EAK@186801|Clostridia	186801|Clostridia	S	ABC-type transport system involved in multi-copper enzyme maturation permease component	-	-	-	-	-	-	-	-	-	-	-	-	ABC2_membrane_2,ABC2_membrane_3
NFNHFNFO_04791	33035.JPJF01000083_gene5157	5.33e-151	426.0	COG1131@1|root,COG1131@2|Bacteria,1TP4J@1239|Firmicutes,253U3@186801|Clostridia,3XZKN@572511|Blautia	186801|Clostridia	V	AAA domain, putative AbiEii toxin, Type IV TA system	-	-	-	ko:K01990,ko:K20490	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00254,M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1,3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC_tran
NFNHFNFO_04792	33035.JPJF01000083_gene5156	1.37e-132	380.0	COG4200@1|root,COG4200@2|Bacteria,1TRRE@1239|Firmicutes,24AHY@186801|Clostridia	186801|Clostridia	S	Lantibiotic protection ABC transporter permease subunit, MutE EpiE family	-	-	-	ko:K20491	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
NFNHFNFO_04793	33035.JPJF01000083_gene5155	1.63e-120	350.0	COG4200@1|root,COG4200@2|Bacteria,1V4AY@1239|Firmicutes,24EXR@186801|Clostridia,3Y0KJ@572511|Blautia	186801|Clostridia	S	Lantibiotic protection ABC transporter permease subunit, MutG family	mutG	-	-	ko:K20492	ko02010,ko02020,ko02024,map02010,map02020,map02024	M00817	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.124.1,3.A.1.124.2,3.A.1.124.6	-	-	ABC2_membrane_4
NFNHFNFO_04794	33035.JPJF01000083_gene5154	1.48e-143	406.0	COG0745@1|root,COG0745@2|Bacteria,1TQ0D@1239|Firmicutes,248WX@186801|Clostridia,3XZUE@572511|Blautia	186801|Clostridia	T	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K20488	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko02022	-	-	-	Response_reg,Trans_reg_C
NFNHFNFO_04795	33035.JPJF01000083_gene5153	4.05e-258	715.0	COG0642@1|root,COG2205@2|Bacteria,1TS1G@1239|Firmicutes,248TF@186801|Clostridia,3Y01W@572511|Blautia	186801|Clostridia	T	subtilin biosynthesis sensor protein SpaK	-	-	2.7.13.3	ko:K20487	ko02020,ko02024,map02020,map02024	M00816	-	-	ko00000,ko00001,ko00002,ko01000,ko01001,ko02022	-	-	-	HATPase_c,HisKA
NFNHFNFO_04796	33035.JPJF01000083_gene5152	1.51e-111	322.0	COG1595@1|root,COG1595@2|Bacteria	2|Bacteria	K	DNA-templated transcription, initiation	-	-	-	ko:K03088	-	-	-	-	ko00000,ko03021	-	-	-	Sigma70_r2,Sigma70_r4_2
NFNHFNFO_04797	33035.JPJF01000083_gene5151	6.81e-229	635.0	2EQDY@1|root,33HZZ@2|Bacteria,1VKNF@1239|Firmicutes,24HVJ@186801|Clostridia	186801|Clostridia	-	-	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04798	545243.BAEV01000053_gene3733	1.1e-43	147.0	COG0454@1|root,COG0454@2|Bacteria,1VD9I@1239|Firmicutes,24MT9@186801|Clostridia,36N6C@31979|Clostridiaceae	186801|Clostridia	K	acetyltransferase	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_1,Acetyltransf_10
NFNHFNFO_04799	33035.JPJF01000083_gene5148	4.23e-156	439.0	2CET8@1|root,2Z7N2@2|Bacteria,1TT9T@1239|Firmicutes,24AN8@186801|Clostridia	186801|Clostridia	S	Psort location Cytoplasmic, score	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04800	33035.JPJF01000083_gene5147	0.0	1268.0	COG2200@1|root,COG2200@2|Bacteria,1TS8B@1239|Firmicutes,24EZ4@186801|Clostridia,3Y288@572511|Blautia	186801|Clostridia	T	Putative diguanylate phosphodiesterase	-	-	-	-	-	-	-	-	-	-	-	-	EAL,GGDEF,PAS_3,PAS_9
NFNHFNFO_04801	33035.JPJF01000083_gene5146	5.35e-118	349.0	COG2199@1|root,COG2199@2|Bacteria,1TQG9@1239|Firmicutes,249KA@186801|Clostridia,3Y0T6@572511|Blautia	186801|Clostridia	T	Diguanylate cyclase, GGDEF domain	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NFNHFNFO_04802	33035.JPJF01000083_gene5144	9.65e-202	563.0	COG0640@1|root,COG0640@2|Bacteria,1V2A1@1239|Firmicutes,24RXK@186801|Clostridia	186801|Clostridia	K	helix_turn_helix, Arsenical Resistance Operon Repressor	-	-	-	-	-	-	-	-	-	-	-	-	HTH_5
NFNHFNFO_04803	33035.JPJF01000083_gene5143	7.58e-303	836.0	COG1132@1|root,COG1132@2|Bacteria,1TSRV@1239|Firmicutes,248P6@186801|Clostridia,3XZUA@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06148	-	-	-	-	ko00000,ko02000	3.A.1	-	-	ABC_membrane,ABC_tran
NFNHFNFO_04804	33035.JPJF01000083_gene5141	3.18e-152	429.0	COG1720@1|root,COG1720@2|Bacteria,1TSBR@1239|Firmicutes,247X5@186801|Clostridia,3XZMC@572511|Blautia	186801|Clostridia	S	Uncharacterised protein family UPF0066	tsaA	-	-	-	-	-	-	-	-	-	-	-	UPF0066
NFNHFNFO_04805	33035.JPJF01000083_gene5139	0.0	1107.0	COG0367@1|root,COG0367@2|Bacteria,1TRPB@1239|Firmicutes,247YA@186801|Clostridia,3XYHI@572511|Blautia	186801|Clostridia	E	Psort location Cytoplasmic, score 8.87	asnB	-	6.3.5.4	ko:K01953	ko00250,ko01100,ko01110,map00250,map01100,map01110	-	R00578	RC00010	ko00000,ko00001,ko01000,ko01002	-	-	-	Asn_synthase,GATase_7
NFNHFNFO_04806	33035.JPJF01000083_gene5138	4.73e-127	362.0	COG0452@1|root,COG0452@2|Bacteria,1TQPT@1239|Firmicutes,24HE6@186801|Clostridia,3XZPE@572511|Blautia	186801|Clostridia	H	dipicolinate synthase subunit B	spoVFB	-	-	ko:K06411	-	-	-	-	ko00000	-	-	-	Flavoprotein
NFNHFNFO_04807	33035.JPJF01000083_gene5137	3.72e-169	476.0	COG0373@1|root,COG0373@2|Bacteria,1UI1H@1239|Firmicutes,249GW@186801|Clostridia,3Y0AN@572511|Blautia	186801|Clostridia	H	Psort location Cytoplasmic, score 8.87	spoVFA	-	-	ko:K06410	-	-	-	-	ko00000	-	-	-	2-Hacid_dh_C,DpaA_N,Shikimate_DH
NFNHFNFO_04808	33035.JPJF01000083_gene5136	7.92e-186	518.0	COG1917@1|root,COG2207@1|root,COG1917@2|Bacteria,COG2207@2|Bacteria,1UZ8Y@1239|Firmicutes,248SM@186801|Clostridia,3XZ0Y@572511|Blautia	186801|Clostridia	K	transcriptional regulator (AraC	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_04809	33035.JPJF01000083_gene5135	1.18e-191	533.0	COG0253@1|root,COG0253@2|Bacteria,1TPMN@1239|Firmicutes,24AGY@186801|Clostridia,3Y2CH@572511|Blautia	186801|Clostridia	E	Diaminopimelate epimerase	dapF	-	5.1.1.7	ko:K01778	ko00300,ko01100,ko01110,ko01120,ko01130,ko01230,map00300,map01100,map01110,map01120,map01130,map01230	M00016,M00525,M00527	R02735	RC00302	ko00000,ko00001,ko00002,ko01000	-	-	-	DAP_epimerase
NFNHFNFO_04811	33035.JPJF01000083_gene5133	1.33e-228	629.0	COG2207@1|root,COG2207@2|Bacteria,1V0IW@1239|Firmicutes,24BME@186801|Clostridia,3Y09S@572511|Blautia	186801|Clostridia	K	helix_turn_helix, arabinose operon control protein	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,Cupin_2,HTH_18,HTH_AraC
NFNHFNFO_04812	33035.JPJF01000083_gene5132	1.58e-288	793.0	COG1653@1|root,COG1653@2|Bacteria,1TQ0V@1239|Firmicutes,2481M@186801|Clostridia,3XZJC@572511|Blautia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	lacE	-	-	ko:K10188	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	SBP_bac_1,SBP_bac_8
NFNHFNFO_04813	33035.JPJF01000083_gene5131	4.93e-201	557.0	COG1175@1|root,COG1175@2|Bacteria,1TPMR@1239|Firmicutes,2494U@186801|Clostridia,3XYXH@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K02025,ko:K10189	ko02010,map02010	M00199,M00207	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.4	-	-	BPD_transp_1
NFNHFNFO_04814	33035.JPJF01000083_gene5130	1.88e-182	508.0	COG0395@1|root,COG0395@2|Bacteria,1TSGI@1239|Firmicutes,24BDH@186801|Clostridia,3XZD9@572511|Blautia	186801|Clostridia	P	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10190	ko02010,map02010	M00199	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.4	-	-	BPD_transp_1
NFNHFNFO_04815	33035.JPJF01000083_gene5129	0.0	1962.0	COG3250@1|root,COG3250@2|Bacteria,1TPDC@1239|Firmicutes,248H7@186801|Clostridia,3XZCD@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	lacZ	-	3.2.1.23	ko:K01190	ko00052,ko00511,ko00600,ko01100,map00052,map00511,map00600,map01100	-	R01105,R01678,R03355,R04783,R06114	RC00049,RC00452	ko00000,ko00001,ko01000	-	-	-	Bgal_small_N,DUF4981,Glyco_hydro_2,Glyco_hydro_2_C,Glyco_hydro_2_N
NFNHFNFO_04816	33035.JPJF01000083_gene5128	0.0	1340.0	COG1874@1|root,COG1874@2|Bacteria,1TQN6@1239|Firmicutes,2488V@186801|Clostridia,3XYX5@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	pbg	-	3.2.1.23	ko:K12308	ko00052,map00052	-	R01105	RC00452	ko00000,ko00001,ko01000	-	-	-	Glyco_hydro_42,Glyco_hydro_42C,Glyco_hydro_42M
NFNHFNFO_04817	411459.RUMOBE_02918	3.05e-73	226.0	COG2206@1|root,COG2206@2|Bacteria,1UI74@1239|Firmicutes,25EC7@186801|Clostridia	186801|Clostridia	T	metal-dependent phosphohydrolase, HD sub domain	-	-	-	-	-	-	-	-	-	-	-	-	HD
NFNHFNFO_04818	33035.JPJF01000083_gene5127	1.16e-71	216.0	COG1380@1|root,COG1380@2|Bacteria,1VEN4@1239|Firmicutes,24MMB@186801|Clostridia,3Y0DT@572511|Blautia	186801|Clostridia	S	Psort location CytoplasmicMembrane, score 9.99	lrgA	-	-	ko:K06518	-	-	-	-	ko00000,ko02000	1.E.14.2	-	-	LrgA
NFNHFNFO_04819	33035.JPJF01000083_gene5126	1.52e-144	409.0	COG1346@1|root,COG1346@2|Bacteria,1TRGN@1239|Firmicutes,24AGM@186801|Clostridia,3XZHZ@572511|Blautia	186801|Clostridia	M	Psort location CytoplasmicMembrane, score	lrgB	-	-	-	-	-	-	-	-	-	-	-	LrgB
NFNHFNFO_04820	33035.JPJF01000083_gene5125	7.1e-113	326.0	COG1102@1|root,COG1102@2|Bacteria,1V82X@1239|Firmicutes,24KX9@186801|Clostridia,3Y0GP@572511|Blautia	186801|Clostridia	F	Cytidylate kinase-like family	-	-	-	-	-	-	-	-	-	-	-	-	Cytidylate_kin2
NFNHFNFO_04821	33035.JPJF01000083_gene5123	7.48e-127	362.0	COG0558@1|root,COG0558@2|Bacteria,1V4YR@1239|Firmicutes,24FWZ@186801|Clostridia,3Y08W@572511|Blautia	186801|Clostridia	I	Belongs to the CDP-alcohol phosphatidyltransferase class-I family	-	-	2.7.8.41	ko:K08744	ko00564,ko01100,map00564,map01100	-	R02030	RC00002,RC00017	ko00000,ko00001,ko01000	-	-	-	CDP-OH_P_transf
NFNHFNFO_04822	33035.JPJF01000083_gene5122	4.52e-239	658.0	COG1609@1|root,COG1609@2|Bacteria,1UXXV@1239|Firmicutes,24A5P@186801|Clostridia,3Y0F1@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_04823	33035.JPJF01000083_gene5121	1.18e-210	585.0	COG1609@1|root,COG1609@2|Bacteria,1VXE7@1239|Firmicutes,252E1@186801|Clostridia	186801|Clostridia	K	Bacterial regulatory proteins, lacI family	-	-	-	-	-	-	-	-	-	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_04824	33035.JPJF01000083_gene5120	3.61e-300	820.0	COG1653@1|root,COG1653@2|Bacteria,1TRY7@1239|Firmicutes,24E82@186801|Clostridia	186801|Clostridia	G	Bacterial extracellular solute-binding protein	-	-	-	-	-	-	-	-	-	-	-	-	SBP_bac_8
NFNHFNFO_04825	33035.JPJF01000083_gene5119	1.39e-201	559.0	COG1175@1|root,COG1175@2|Bacteria,1TRU7@1239|Firmicutes,24AIC@186801|Clostridia,3XYIT@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K02025,ko:K05814,ko:K10201,ko:K17316	ko02010,map02010	M00198,M00205,M00207,M00605	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1,3.A.1.1.18,3.A.1.1.24,3.A.1.1.3,3.A.1.1.30	-	-	BPD_transp_1
NFNHFNFO_04826	33035.JPJF01000083_gene5118	8.05e-194	538.0	COG0395@1|root,COG0395@2|Bacteria,1TPRG@1239|Firmicutes,249ZC@186801|Clostridia,3XZXP@572511|Blautia	186801|Clostridia	G	Binding-protein-dependent transport system inner membrane component	-	-	-	ko:K10119	ko02010,map02010	M00196	-	-	ko00000,ko00001,ko00002,ko02000	3.A.1.1.28	-	-	BPD_transp_1
NFNHFNFO_04827	33035.JPJF01000083_gene5117	0.0	1033.0	COG5512@1|root,COG5512@2|Bacteria,1TR27@1239|Firmicutes,247Z8@186801|Clostridia	186801|Clostridia	S	Domain of unknown function (DUF5060)	-	-	-	-	-	-	-	-	-	-	-	-	DUF4038,DUF5060
NFNHFNFO_04828	33035.JPJF01000083_gene5116	1.66e-215	597.0	COG1609@1|root,COG1609@2|Bacteria,1UXXV@1239|Firmicutes,24A5P@186801|Clostridia,3Y0F1@572511|Blautia	186801|Clostridia	K	Psort location Cytoplasmic, score 9.98	-	-	-	ko:K02529	-	-	-	-	ko00000,ko03000	-	-	-	LacI,Peripla_BP_3
NFNHFNFO_04829	33035.JPJF01000083_gene5115	0.0	883.0	COG2407@1|root,COG2407@2|Bacteria,1TQDX@1239|Firmicutes,247N8@186801|Clostridia,3XZNR@572511|Blautia	186801|Clostridia	G	Psort location Cytoplasmic, score 8.87	-	-	-	-	-	-	-	-	-	-	-	-	Arabinose_Isome,Fucose_iso_C
NFNHFNFO_04830	33035.JPJF01000083_gene5114	1.23e-191	532.0	COG3959@1|root,COG3959@2|Bacteria,1TT51@1239|Firmicutes,247IK@186801|Clostridia,3XZKM@572511|Blautia	186801|Clostridia	G	Transketolase, thiamine diphosphate binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transketolase_N
NFNHFNFO_04831	33035.JPJF01000083_gene5113	3.53e-203	564.0	COG3958@1|root,COG3958@2|Bacteria,1V0K5@1239|Firmicutes,24914@186801|Clostridia,3XZKV@572511|Blautia	186801|Clostridia	G	Transketolase, pyrimidine binding domain	-	-	2.2.1.1	ko:K00615	ko00030,ko00710,ko01051,ko01100,ko01110,ko01120,ko01130,ko01200,ko01230,map00030,map00710,map01051,map01100,map01110,map01120,map01130,map01200,map01230	M00004,M00007,M00165,M00167	R01067,R01641,R01830,R06590	RC00032,RC00226,RC00571,RC01560	ko00000,ko00001,ko00002,ko01000	-	-	-	Transket_pyr,Transketolase_C
NFNHFNFO_04832	33035.JPJF01000083_gene5112	0.0	886.0	COG0554@1|root,COG0554@2|Bacteria,1TRX3@1239|Firmicutes,24A76@186801|Clostridia,3XZRZ@572511|Blautia	186801|Clostridia	C	FGGY family of carbohydrate kinases, C-terminal domain	-	-	2.7.1.30	ko:K00864	ko00561,ko01100,ko03320,ko04626,map00561,map01100,map03320,map04626	-	R00847	RC00002,RC00017	ko00000,ko00001,ko01000,ko04147	-	-	-	FGGY_C,FGGY_N
NFNHFNFO_04834	33035.JPJF01000083_gene5107	1.9e-204	568.0	COG0697@1|root,COG0697@2|Bacteria,1TRH8@1239|Firmicutes,24B85@186801|Clostridia,3Y05N@572511|Blautia	186801|Clostridia	EG	COG COG0697 Permeases of the drug metabolite transporter (DMT) superfamily	-	-	-	-	-	-	-	-	-	-	-	-	EamA
NFNHFNFO_04835	33035.JPJF01000083_gene5106	1.8e-190	530.0	COG4977@1|root,COG4977@2|Bacteria,1V166@1239|Firmicutes,25EAI@186801|Clostridia	186801|Clostridia	K	AraC-like ligand binding domain	-	-	-	-	-	-	-	-	-	-	-	-	AraC_binding,HTH_18
NFNHFNFO_04836	658086.HMPREF0994_01696	2.69e-95	283.0	COG1670@1|root,COG1670@2|Bacteria,1UYRS@1239|Firmicutes,249WX@186801|Clostridia,27SE0@186928|unclassified Lachnospiraceae	186801|Clostridia	J	Acetyltransferase (GNAT) domain	-	-	-	-	-	-	-	-	-	-	-	-	Acetyltransf_3
NFNHFNFO_04837	33035.JPJF01000083_gene5104	0.0	1091.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia,3XZJG@572511|Blautia	186801|Clostridia	V	Psort location CytoplasmicMembrane, score 10.00	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFNHFNFO_04838	33035.JPJF01000083_gene5103	8.07e-14	70.1	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFNHFNFO_04839	33035.JPJF01000083_gene5103	0.0	1050.0	COG1132@1|root,COG1132@2|Bacteria,1TP0B@1239|Firmicutes,247Q0@186801|Clostridia	186801|Clostridia	V	ABC transporter	-	-	-	ko:K06147	-	-	-	-	ko00000,ko02000	3.A.1.106,3.A.1.109,3.A.1.21	-	-	ABC_membrane,ABC_tran
NFNHFNFO_04840	33035.JPJF01000084_gene5086	3.14e-230	640.0	COG2199@1|root,COG2199@2|Bacteria,1UZKR@1239|Firmicutes,25EAM@186801|Clostridia	186801|Clostridia	T	diguanylate cyclase	-	-	-	-	-	-	-	-	-	-	-	-	GGDEF
NFNHFNFO_04841	33035.JPJF01000084_gene5087	3.61e-249	686.0	COG0582@1|root,COG0582@2|Bacteria,1TTJI@1239|Firmicutes,24B23@186801|Clostridia,3Y00V@572511|Blautia	186801|Clostridia	L	Phage integrase, N-terminal SAM-like domain	-	-	-	-	-	-	-	-	-	-	-	-	Phage_int_SAM_3,Phage_integrase
NFNHFNFO_04842	33035.JPJF01000042_gene361	1.28e-225	630.0	COG0675@1|root,COG0675@2|Bacteria,1TT7D@1239|Firmicutes,24EJK@186801|Clostridia,3Y163@572511|Blautia	186801|Clostridia	L	Putative transposase DNA-binding domain	-	-	-	-	-	-	-	-	-	-	-	-	OrfB_Zn_ribbon
NFNHFNFO_04844	768706.Desor_5122	3.44e-179	508.0	COG0399@1|root,COG0399@2|Bacteria,1TPDH@1239|Firmicutes,24862@186801|Clostridia,25ZZI@186807|Peptococcaceae	186801|Clostridia	E	PFAM DegT DnrJ EryC1 StrS aminotransferase family	-	-	2.6.1.33	ko:K20429	-	-	R02773	RC00006,RC00781	ko00000,ko01000	-	-	-	DegT_DnrJ_EryC1
NFNHFNFO_04845	944565.HMPREF9127_0876	1.03e-74	236.0	COG2148@1|root,COG2148@2|Bacteria,1TP49@1239|Firmicutes,249F1@186801|Clostridia,22JAN@1570339|Peptoniphilaceae	186801|Clostridia	M	Bacterial sugar transferase	-	-	-	-	-	-	-	-	-	-	-	-	Bac_transf
NFNHFNFO_04846	1235803.C825_04223	1.68e-39	152.0	COG0151@1|root,COG0151@2|Bacteria,4PNYW@976|Bacteroidetes,2G11U@200643|Bacteroidia,22YSJ@171551|Porphyromonadaceae	976|Bacteroidetes	F	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain	-	-	-	-	-	-	-	-	-	-	-	-	ATP-grasp_4
NFNHFNFO_04847	742733.HMPREF9469_01997	1.58e-214	605.0	COG2079@1|root,COG2079@2|Bacteria,1TSD7@1239|Firmicutes,24BFZ@186801|Clostridia	186801|Clostridia	S	MmgE PrpD family protein	-	-	-	-	-	-	-	-	-	-	-	-	MmgE_PrpD
NFNHFNFO_04848	742733.HMPREF9469_01996	3.3e-176	497.0	COG0667@1|root,COG0667@2|Bacteria,1TQJC@1239|Firmicutes,25B10@186801|Clostridia	186801|Clostridia	C	aldo keto reductase	-	-	-	-	-	-	-	-	-	-	-	-	Aldo_ket_red
NFNHFNFO_04849	742733.HMPREF9469_01995	2.03e-190	538.0	COG0028@1|root,COG0028@2|Bacteria,1TSJZ@1239|Firmicutes,24AIU@186801|Clostridia,22238@1506553|Lachnoclostridium	186801|Clostridia	EH	Thiamine pyrophosphate enzyme, N-terminal TPP binding domain	aepY	-	4.1.1.82	ko:K09459	ko00440,ko01100,ko01120,ko01130,map00440,map01100,map01120,map01130	-	R04053	RC00506	ko00000,ko00001,ko01000	-	-	-	TPP_enzyme_C,TPP_enzyme_N
NFNHFNFO_04850	742733.HMPREF9469_01994	1.23e-197	549.0	COG0826@1|root,COG0826@2|Bacteria,1TT8S@1239|Firmicutes,2527T@186801|Clostridia	186801|Clostridia	O	Peptidase family U32	-	-	-	-	-	-	-	-	-	-	-	-	-
NFNHFNFO_04851	742733.HMPREF9469_01993	6.56e-255	701.0	COG2301@1|root,COG2301@2|Bacteria,1TSF2@1239|Firmicutes,249TC@186801|Clostridia	186801|Clostridia	G	C-C_Bond_Lyase of the TIM-Barrel fold	-	-	-	-	-	-	-	-	-	-	-	-	C-C_Bond_Lyase
NFNHFNFO_04852	742733.HMPREF9469_01992	1.94e-91	270.0	COG1838@1|root,COG1838@2|Bacteria,1V3K8@1239|Firmicutes,250YK@186801|Clostridia	186801|Clostridia	C	Fumarase C-terminus	-	-	4.2.1.2	ko:K01678	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase_C
NFNHFNFO_04853	742733.HMPREF9469_01991	1.94e-160	454.0	COG1951@1|root,COG1951@2|Bacteria,1UY6Q@1239|Firmicutes,24XUA@186801|Clostridia	186801|Clostridia	C	Fumarate hydratase (Fumerase)	-	-	4.2.1.2	ko:K01677	ko00020,ko00620,ko00720,ko01100,ko01110,ko01120,ko01130,ko01200,map00020,map00620,map00720,map01100,map01110,map01120,map01130,map01200	M00009,M00011,M00173,M00374,M00620	R01082	RC00443	ko00000,ko00001,ko00002,ko01000	-	-	-	Fumerase
NFNHFNFO_04854	697329.Rumal_3609	2.51e-152	451.0	COG2244@1|root,COG2244@2|Bacteria,1TR1W@1239|Firmicutes,24917@186801|Clostridia,3WHMM@541000|Ruminococcaceae	186801|Clostridia	C	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	Polysacc_synt
NFNHFNFO_04856	1163671.JAGI01000002_gene3765	1.41e-69	218.0	COG0194@1|root,COG0194@2|Bacteria,1V3RZ@1239|Firmicutes,24HKC@186801|Clostridia,36I87@31979|Clostridiaceae	186801|Clostridia	F	Guanylate kinase	gmk_1	-	2.7.4.8	ko:K00942	ko00230,ko01100,map00230,map01100	M00050	R00332,R02090	RC00002	ko00000,ko00001,ko00002,ko01000	-	-	-	Guanylate_kin
NFNHFNFO_04857	1298920.KI911353_gene649	1.3e-103	303.0	COG1878@1|root,COG1878@2|Bacteria,1V2DJ@1239|Firmicutes,24HUC@186801|Clostridia,223DU@1506553|Lachnoclostridium	186801|Clostridia	S	Putative cyclase	-	-	-	-	-	-	-	-	-	-	-	-	Cyclase
NFNHFNFO_04858	476272.RUMHYD_02287	0.0	883.0	COG2217@1|root,COG2217@2|Bacteria,1TP5S@1239|Firmicutes,247MW@186801|Clostridia,3XZ6B@572511|Blautia	186801|Clostridia	P	Psort location CytoplasmicMembrane, score	-	-	-	-	-	-	-	-	-	-	-	-	E1-E2_ATPase,Hydrolase
NFNHFNFO_04859	556261.HMPREF0240_01540	5.78e-57	177.0	COG1937@1|root,COG1937@2|Bacteria,1V7GT@1239|Firmicutes,25B4K@186801|Clostridia,36W9E@31979|Clostridiaceae	186801|Clostridia	S	Metal-sensitive transcriptional repressor	-	-	-	ko:K21600	-	-	-	-	ko00000,ko03000	-	-	-	Trns_repr_metal
NFNHFNFO_04860	1235799.C818_00348	4.1e-13	73.6	COG1309@1|root,COG1309@2|Bacteria,1V7BK@1239|Firmicutes,24HI0@186801|Clostridia,27PZS@186928|unclassified Lachnospiraceae	186801|Clostridia	K	Bacterial regulatory proteins, tetR family	grdR	-	-	-	-	-	-	-	-	-	-	-	TetR_N
## 4597 queries scanned
## Total time (seconds): 421.3505165576935
## Rate: 10.91 q/s