LOCUS       gnlProkkaECNEEKLO_96   11768 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ECNEEKLO_96.
ACCESSION   gnlProkkaECNEEKLO_96
VERSION     gnlProkkaECNEEKLO_96
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 12:41:21
            Original ID  :: gnl|Prokka|ECNEEKLO_96
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 11768
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..11768
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[2454:6768]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      2455..6768
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..11768
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..11768
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             3..1232
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 70.1;
                     E-value: 2.2e-21)"
                     /gene_kind="transport"
                     /locus_tag="ctg53_1"
                     /transl_table=11
                     /translation="MRGAVYRPGIYQLSGKLNTIRELVHEAQGLTGDAFLNRAVLYRQR
                     EDLTSEVVQIDIKSIMDGTSPNLALMKNDILYIPSIHDLEDRGNVTVHGEVAQPDSYPY
                     ADNMTLEDLIIQAGGLKEAASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFVIDG
                     QPGFILEPYDQVYVRRSPGYQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTN
                     YAYLRGAKLTRVANASEKKRMGDVIRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALS
                     NPKSNADLVLREGDVISIPKNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNA
                     RKSKKFIVYMNGQVTKVKGSGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMM
                     IASIANLIKK"
     CDS             1243..2391
                     /locus_tag="ctg53_2"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVLFGKSLLASLRKELKNKEIEQDK"
     CDS             2455..3174
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 56.8; E-value:
                     3.3e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_3"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.8e-17, bitscore:
                     52.2, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CGIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             3195..4496
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 207.4;
                     E-value: 4.4e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_4"
                     /sec_met_domain="CTP_transf_like (E-value: 2.3e-13,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 6.1e-121, bitscore:
                     392.9, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 2.9e-63, bitscore:
                     203.5, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKEGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKTILENERALEVRELCMPIKEILELIPGTK"
     CDS             4513..5637
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 58.1;
                     E-value: 1.1e-17)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_5"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.3e-20, bitscore:
                     63.7, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.1e-20, bitscore:
                     64.0, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGP
                     VLLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             5647..6768
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg53_6_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg53_6"
                     /sec_met_domain="Aminotran_5 (E-value: 1.8e-31, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        5737..6744
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg53_6_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg53_6_Aminotran_5.1"
                     /locus_tag="ctg53_6"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             6765..7241
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 70.3;
                     E-value: 2.9e-21)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg53_7"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYSNIY
                     LGKNAEIRSGCYLIARDKIIIGENSTLAYGTTILTTADPNGPYNALAILYPYKKAPVVI
                     GDNVWIGANVTILPGITIGDYVVVAAGSVVTKDVPSGVLVAGVPAVVKKQLLME"
     CDS             7310..8131
                     /locus_tag="ctg53_8"
                     /transl_table=11
                     /translation="MKDKTCHIITDDNIKEIELSILKYIDLQCKKYNLRYYLGYGTLLG
                     AVRHQGFIPWDDDIDIWMPREDYDKFISLENSLENSKFKILSPLNNSDYYYGFAKLVSR
                     NTELQEIGFLPIKDYGVYVDIFPLDNIATEHPFLHFIAKYIIMARIASCNIKPWLNLTH
                     KKKAILFRFIGIIGTLLGFRRTAKLTDKIAKIDKGKTNKRVGVFVESIGEHNIFATEYF
                     ASTIQLKFEGIYFNAPKEYRKCLTQLYGDYMQLPPENRRISGHSFKACYRL"
     CDS             8116..8874
                     /locus_tag="ctg53_9"
                     /transl_table=11
                     /translation="MLQIMKLTTYVLNLLKDKERKEYMQYVLSDYPNLDIQYVNAINGK
                     NLSLDEILNQFDNNKAYKRYGRECDLGEIGCSLSHRLAFDLLMNSESNYALILEDDIVI
                     GDGFSSVLEKLLPLIDIDAPCVILLSGGVSYYKKRYYNTLCLGVVYMGDYAHSYLINKA
                     AAKLILDDKKAYIFADDWDYIRNRGVNVLVILPHLVDQRRDGSFVSNVWQDNHHIVKVK
                     LSLIRLCNYILSRIIDKILKRMGNYENKTL"
     CDS             8876..10411
                     /locus_tag="ctg53_10"
                     /transl_table=11
                     /translation="MVESRSKKGIANIKCSLFFYIVNLFLNIISRKVFIDYLGIEVLGL
                     NTTVTNLLSFLNLAELGIGNAIAFTLYKPLFLKDFQVIREIVSVQAWLYRRIAYFISIG
                     ALGLMLLFPVIFKKIDLPLWYAYATFIVLLIASLLSYFVNYKQILLSADQKEYKITLCV
                     QGIKSLKTITQVVVILYLINGYVYWLTLELVGVLVSALLLNKIVNKEYPWLFVKVSDGK
                     KLRNKYPEIIVKTKQFFFHRISSFVLNQTSPLIIYAFASLTMVAIYGNYMLIVFGGIAL
                     VNAFFNGFNAGVGNLVAEGDKKKIKSFFWEITSFRIWIAAIICVCFFKLCHPFISLWVG
                     KEYVLDEMTFIVLTIYVFISLTRVNEAFLFAYGLYQDIWAPIIEAILNLGLSVLLGFIW
                     GLTGIISGVVISLVVIVCIWKPYFLFKMGFKDNILEYVSRYIKYYMMIALSFILSHLIL
                     NTMFIDFQSSYWKLFEYACTVGSCYAILSFLFFYLFDNGMRQFTRRLLNIFLK"
     CDS             10481..11494
                     /locus_tag="ctg53_11"
                     /transl_table=11
                     /translation="MSFYIFIFVVLLYFSFRKYNKYIYWGTILLLSLIAGLRSETIGVD
                     THAYKDIFIWISNEVLYPIEPAWYFLNKLIAWVGGSFNFLLWITALLTLIPIGVVSLRC
                     SSNPQMSLFFYYGLYAYINSFNGMRQFVAISFVLLAYSYITQKKNFFLYLLIAFIFHYS
                     AIFSFIAILVDKVSLTKRRVIGGIFSSFFVGMFFNDSMFLVLAGPYAGYLESSEGYRDN
                     FLLAAIMAILMSCLYMCTFFTLRREYKQNLWTKMFFVGIIILNITMRLELGARIILYFT
                     LCQIIFYPMYFRHNIVKNKRMVVLSILLYTSLVFMKILILGNQGEYSVYPYKTILW"
ORIGIN
        1 aaatccgtgg cgctgtctat cgtcccggta tctaccagct cagcggtaaa ctgaacacga
       61 tccgcgaact tgtccatgaa gctcagggtc tgaccggtga cgctttcctg aatcgtgccg
      121 tcctctatcg ccagcgtgaa gacctgacca gtgaagttgt tcagatagac attaagtcta
      181 tcatggacgg cacttcccca aaccttgccc tgatgaagaa tgacatcctc tacattccaa
      241 gtatccatga cctggaagac cggggtaatg tcacagttca cggtgaggtt gcccaacctg
      301 attcctatcc ttatgcggat aacatgacac ttgaggatct gatcattcag gccggtggct
      361 tgaaagaagc cgcctctact gtccgtattg atatatcgag acgaatcaag aatcctcgta
      421 gtactgcgga taatgatacg attggtcaga tgtatacctt ctctttaaag gatggttttg
      481 taatagatgg tcagcccggt tttatccttg agccttatga tcaggtttat gtccgtcgca
      541 gtccgggcta tcaggcacaa cagaatgtag ccattgaagg tgaaatcctt ttcggaggaa
      601 attacgccat gaccagccgt gaggaacgtc tttccgattt agtgaataaa gccggcggtc
      661 cgaccaatta tgcctatctg cgtggtgcga aactgacccg tgtggctaac gctagtgaaa
      721 agaaacgtat gggtgatgta attcgcctta tgagcaggca attgggcgaa gccatgattg
      781 actctttggg tattcgtgtt gaagatactt ttacggttgg aatagatttg gaaaaagcct
      841 tgagcaatcc taaaagtaat gccgatcttg tcttacgtga aggtgatgtg atctccatac
      901 ctaagaatac taatactgta actatcaatg gtgctgtcat ggttccgaat acggtttctt
      961 atatgaaggg aaagaatgtg gattattacc tgaatcaggc cggtggctgt tctgataatg
     1021 caaggaagag taagaagttc attgtttaca tgaatggtca ggtgacgaag gttaagggta
     1081 gtggtaagaa acagattgag ccggggtgtg agattattgt gcctggtaag gctaagaaga
     1141 aagggaacat agctaatatt ttaggttatg ctacttcctt cagttctttg ggaatgatga
     1201 ttgcttctat tgctaatttg ataaagaaat aaatgaccta ttatgattga aaagcaatct
     1261 tatcaagaac cgttttctga agtggataaa aggaaagatg atgaaatgga aatagacttg
     1321 atggctattt tttataagat tattactgtt cgtggagtac tatgcaaagc tgctggagtg
     1381 ggagtaataa ttgctatagt ggtggcattg agcattccca agcaatatac agtaaaggtt
     1441 accctttctc ctgaaatggg taatgcgaag ggaagtaatg gtttagccgg acttgctgcc
     1501 tcgtttttgg gagatggggc tctaataggg gaaagcacag atgccttgaa cgcttctctt
     1561 tcagcagata ttgtttcttc aactcctttt ttattggaac ttttagaaat ggaagtctcc
     1621 gtttctaaaa aggatgataa aatgactttg gggtcttatc tcgatgaaga gtcatctcct
     1681 tggtgggatt atcttatagg ttttccgggc atagtaatag gaggagttaa atcattattc
     1741 ggagaagata cggttcctgc cagtggaggg cggcaaggaa ctatcgaatt gacgaaagaa
     1801 gtaaatgaga agattaattt tcttaaaaag aagattagtg catccattga taagaaaacc
     1861 gccataacga gcattacggt caccttacaa aatccgcaga tcactgcggt tatagcagat
     1921 tctgtcgttc ataaattaca ggaatatatt attgggtatc gaacttcaaa agtaaaagaa
     1981 gactgtgcgt atttggaacg gttgtttaaa gaacgtcagc aggaatatta tgctgctcaa
     2041 agaaaatatg cggattatgt agacgcccat gataatgtgg ttcttcaaag tgtacgtgct
     2101 gagcaggagc gtttacagaa cgacatgagt ttggcttatc agatatatag tcaggttgct
     2161 aatcagttgc aggtatccag agccaaagta caggaggaaa agccagtctt tgcagtagtt
     2221 gagcctgccg ttgtaccttt gaaaccttca ggtatgggac tcaaaattta tattttatta
     2281 tttgtgttcc tgtccgtatc tggtactctc gtgtgggtgc tttttggcaa aagtctgctg
     2341 gctagcttga gaaaagaact gaaaaataag gagatagaac aggataaatg atgctaaaac
     2401 gtcgtttaca acattcttac atcaattaaa ttcacttact atattattaa acgaatgata
     2461 cgtacagcta tgataatggc tgcgggcatg ggaacccgtt ttggccaata tacagaattg
     2521 atacctaaag ggttcgtcaa agtgggaggt attccaatga tagttcgttc tattgatact
     2581 ttgttatcat gtggcattga gcgaattgta atcggtacag gatataaaca agaagtttat
     2641 gaagaattga agacagacta tcctatgctt gaaacctgtt ttagtcctcg ttatgctgaa
     2701 acaaatagta tgtatacttt atataatacg cgggagattc tgggcaatga tgatttttta
     2761 ttgttagagt cagatttgat ttttgagaaa caagcaataa tgagcttatt ggagtgtcct
     2821 gcggcagatg caatgctaat aactccagtg acaaagtttc aagatcagta ttatgtggaa
     2881 catgatgata attttcgcct ttcttcatgt tctgtcaata agaataaact aaacgctaaa
     2941 ggcgaattgg tcggcatcca taaactatcc ggttcctttt acaaaataat gtgtgctgat
     3001 tatgcgagta ttgttgatga acaacccaat ttgggatatg agtatgaatt actacgaata
     3061 tcttgttctc aatctcctgt ttatgtgcat aaagtagaag ggctgaaatg gtatgaaatc
     3121 gatgacatat cagatttgga atatgcagag aaatatattg ttccgtattg ttaattaaaa
     3181 taatatatca aattatgagt aagacagttt atattgggat gactgcggat attatgcatc
     3241 caggacttat ccgcattatt aatgaggcta ctaaatacgg tgatgttata attggtcttc
     3301 ttacagataa agctattgcg gagcataaac gccttcctta tctgacctat gaacaacgaa
     3361 aagaggtagt tcagaatatt aaaggcgtat gtaaagttgt tcctcaagaa gaatggagct
     3421 atgttgagaa tctcaaacgc attaaacctg actatataat tcatggtgac gactggaaaa
     3481 ccgggccttt acgtgaagaa cgtgtgcgcg tatttgaagt gatgaatgaa cagggaggaa
     3541 aggttatcga aattccatat actttgggaa ttaattcatc ttctttggat aaagatatta
     3601 aggctatagg tacaacccct gatgtacgtt taaaatcact tcgtcgtttg ataaatgcca
     3661 aacccgtagt tcgtattttg gaagctcatg atggactatg tggcttgata attgaaaatc
     3721 aggaaatatt aaaaggggat aagagggaag tatttgacgg aatgtggtct agtagcctta
     3781 cggattcaac cagtaaaggt aaacctgata ttgaggcggt tgatttaact acccgattgc
     3841 aagatttgaa taatattctg gagtgtacta ctaaacctat tatttttgat ggagatacag
     3901 gtggtaaaat tgaacatttc gtatttacag tacgcacttt agaacgtcat ggaatttcag
     3961 ctataataat tgaagataaa gttggattaa aaaagaattc attgtttggt acagatgtta
     4021 ttcaaactca agatacaatc gaaggtttct gtaataagat caaagaagga aaggcatctc
     4081 agattactga tgattttatg attatcgctc gtattgagag ccttatagcg ggaaagccgg
     4141 taagtgatgc tttagagaga gcttttgcat atgtccaagc gggagcggac ggtattatga
     4201 tacatagcaa aaataagtcg ggtgaagata taaaagaatt ttgtttggcg tttcgaaaac
     4261 agtatgctca tgtacctatc gtggttgtgc ctactacata tgatcatatt tatgagtctg
     4321 aattgtgtga ttggggtgtg aatataatta tttatgctaa tcatatgctt cgtgccgctt
     4381 atcctgctat gatgaatgtc gcaaagacaa tattagagaa tgaacgtgct ttagaggtgc
     4441 gcgaactgtg tatgcccata aaagaaatat tggaactgat tccaggtact aaataaaaag
     4501 aggaatatca ttatgttaag cgtagaaaaa gtttatgaaa cgtttctgag tcatgacgtt
     4561 gattttttta caggagttcc agactcatta ctaaaaaata tttgtgccta tatcacagac
     4621 catacttcac gtgagaaaca tatcatagct gctaatgaag gtgcggctgt aggaattgct
     4681 tcaggttatt atatggcatc aggtaaggtt cctgtggttt atatgcaaaa ttccggcttg
     4741 ggtaatactg ttaatcctct gctgtctctt gcagatgaac aagtatacag ttttccaatg
     4801 cttttgatga ttggctggcg tggtgaaccg ggaacaaaag atgaacctca gcataaaaaa
     4861 cagggtgagg taactttaga tttgttgaaa gcaatgcgga ttccttatat aattcttgat
     4921 tcaaatgaga atgatgcatt tattcagctc catgatatca tacaatcagc aaaaactaag
     4981 aatattcctc atgcaataat tattcggaaa gatgtttttg gcaaatataa acttcaaaaa
     5041 gagtttggat gtaattatcc tttatctcgt gaggatgctt tgcaaatagt tgtggattat
     5101 ctgcctgaaa attcagtggt cgtttctact actggcaagc tttctcgtga gttatttgaa
     5161 tatcgagaaa tgaaagagca aggtcatgaa catgattttc tcacggtagg ctctatggga
     5221 catagttcat caatctcttt gggtattgct atagcaaagc aagatagacc tgtttattgc
     5281 ttggatggtg atggagcatt tattatgcat ttaggggcaa ttagtaacat tggcgattta
     5341 tctcctaaaa actattatca tattttgttt aacaatggtg ctcacgagtc tgtaggagga
     5401 cagcctactt taggatttag tttagatatt ccggctattg tccgggggag cggatataag
     5461 catacttata ctgtttgtac aaaagttgaa attgaagaag caatgaagca gcttccaaag
     5521 ttatgtggtc ctgttttgtt ggaaataaag gttaaaatag attctcggga gaatttggga
     5581 cgtcccacga ctactcctat agagaataag gagcatttta tggatttttt aaaataaata
     5641 tattcgatga aaatagaaag aaaaatatta ttaaatcctg ggcctgccac tactactgac
     5701 agtgtaaaaa tggcacaagt tgttccggat atttgtcctc gcgagaaaga attcgcaggt
     5761 atgatgaaac aacttcggga cgatttggtc agagttgctc atgggaattt ggaaaaacat
     5821 accgctgtat tattttgtgg ctcaggaacc atcaatattg atatatgtct aaattctctt
     5881 cttcctgaag acaaaagggt gcttatagtg aataatgggg catatagtac ccgtgctgta
     5941 gaagtgtgtc aatattatgg tttgcctcat attaatttgg aattttccgt ttatgaacgt
     6001 cctgatttat cggtggtgga aaatgtgttg caagaaaatc ctgatatagc tatggtttat
     6061 actactcatc acgagacggg tacaggaatt ctgaacccta ttcgcgagat gggcgctata
     6121 gctcataaat atcaggctaa atttgtcgtc gatactactt cttctttggg catgattcct
     6181 tttgatatag agaaagataa tgtggatttt tgtatggcat ctgctcaaaa aggacttcaa
     6241 gcgatgacag gtctttcttt tattataggc aatgaggaac agattaagtt ttcaaaaaaa
     6301 tatcccaagc gttcttacta ttgtaatctt tatttgcagt atgagaattt tgagagaaca
     6361 ggtgaaatgc attttactcc accggtacaa actatttacg ccactcgtca ggcattaaat
     6421 gaatattttg aagtgggcga agaagctaag tttgcccgtc acaaaagagt ttttgaggct
     6481 attcattcag gtataaatga aattggtctt aaaagtgtaa taaagcgtga atggcagtca
     6541 ggactggttg tctcagttca atacccagaa gatcccaact gggattttga gaaaatacat
     6601 gattattgtt atgagcgtgg atttacgatt tatccaggta agatatcaac tgaggatact
     6661 tttagaatct gtgctttagg agagatagaa gtagatgata ttgagaactt ctttaaagta
     6721 ctaaaagctg cattaaatca ttataacgtc acattaccga tgtcatgatt gcagaaatat
     6781 tattgaagat tcgtcatttt tatttttccc ttcgtggtat acacttccat ccggaaagtg
     6841 ttatttctgg agtgcctatt cgtagctttc gcttagtagg caaatatagc aatatctatt
     6901 tgggtaaaaa tgctgaaata cgttcaggct gttatctgat tgctcgtgat aaaatcatta
     6961 ttggagaaaa ctcaacactc gcctatggaa cgactatatt gacaactgct gatcctaatg
     7021 gaccgtataa tgcattagca attctttatc cttataaaaa ggcaccggta gttataggag
     7081 ataatgtttg gattggggct aatgttacca tccttcctgg aataactatt ggtgattacg
     7141 ttgtagtagc agctggatct gttgtaacaa aagatgtacc ttcaggggta ttggttgctg
     7201 gtgtaccagc tgttgtgaaa aaacagcttt tgatggaata agaataattg ttttattctt
     7261 attgtcagac aatatcatta cataagaagt ataatttaat gcctcaataa tgaaagataa
     7321 aacttgtcat ataataacag atgataatat aaaagaaata gaattatcta tattgaaata
     7381 tattgattta caatgtaaaa agtacaatct aaggtattat ttgggatatg gtactttatt
     7441 gggagcagtg cgtcatcaag gtttcattcc ttgggatgac gacattgata tctggatgcc
     7501 acgggaggat tatgacaaat ttataagttt agaaaattca ttggaaaact caaagtttaa
     7561 gattttatct cctttgaaca attcagatta ttattatgga tttgctaaac tagtatcaag
     7621 aaatacagaa cttcaggaaa taggatttct tcctattaag gattatggtg tatatgtgga
     7681 tatttttcct ttggataata ttgcaacgga gcatccgttt ttacatttca tagctaaata
     7741 tataataatg gcaaggattg cgtcttgtaa tataaaacct tggttaaatc tgacgcataa
     7801 gaaaaaagct attttatttc gctttatagg aataattggg acattgttag gatttcgaag
     7861 aacagcaaaa ttaacggata agatagctaa aatagataag ggtaaaacga ataaaagggt
     7921 gggggtcttt gttgaaagca taggagagca taatatattt gcaacagaat attttgcttc
     7981 tacaatacag ttgaaatttg agggaatata ttttaatgct ccaaaggaat atcgaaaatg
     8041 tttgactcag ctttatggag attatatgca actacctccc gaaaatagac gcatttctgg
     8101 tcattcattt aaagcatgtt acagattatg aaactaacaa catatgttct taatttattg
     8161 aaagataaag aacgaaaaga atatatgcaa tatgtattga gcgattatcc taatctagat
     8221 attcaatatg ttaatgcaat aaatggaaaa aatcttagtc tggatgagat attgaatcaa
     8281 tttgataata ataaagcata caaacgctat ggaagagaat gtgatttagg agaaattggg
     8341 tgcagtttga gtcatcgatt ggcgtttgat ttattaatga attcggagag taactatgct
     8401 ttaattttag aagatgatat tgttattggg gatggattta gtagcgtatt ggaaaaatta
     8461 ttgccattga ttgatatcga tgctccttgt gttattttat tgtcaggtgg tgtctcttat
     8521 tataaaaaaa gatattataa tactttgtgt ttgggtgtag tttatatggg agattatgcg
     8581 catagttatt taataaataa ggctgctgct aaattaatat tggatgataa aaaagcgtat
     8641 atatttgctg atgattggga ttatatacgt aatagaggag taaatgtact agttatttta
     8701 cctcatttag ttgatcaacg tagagatgga agttttgtaa gtaatgtttg gcaagataat
     8761 caccatattg tgaaggtgaa attatcattg attaggttgt gtaactatat tctttcaagg
     8821 ataatagata aaatattgaa gcgaatggga aattatgaga ataagacact gtagtatggt
     8881 tgaatcacgt tctaaaaaag gtatagcaaa tataaaatgt tctttgtttt tttatatcgt
     8941 aaacttattt cttaatatta tatctagaaa ggtctttatc gattatttag gaatagaagt
     9001 actaggactt aacacaacag ttactaatct gcttagtttt ctaaatttgg cagaattggg
     9061 aattggtaac gcaattgcat ttactttata taaaccttta tttttgaaag attttcaagt
     9121 tataagggag atagtgtctg ttcaagcttg gctttatcga cgaattgcat attttatatc
     9181 tataggtgct ttaggactaa tgttgctttt tcctgtaatt tttaaaaaaa tagatttacc
     9241 tttgtggtat gcttatgcta catttattgt tttattgata gcttctttgt tgagctattt
     9301 tgtgaattat aaacagatac ttctaagtgc agatcaaaaa gaatacaaaa taacactttg
     9361 tgtacaggga ataaaatcat taaaaaccat aacacaagtg gttgttatat tatatctaat
     9421 aaatgggtat gtgtattggt taactcttga acttgtgggg gtattggttt cagctttgct
     9481 attaaataaa attgtaaaca aagaatatcc ttggttgttt gtaaaggtct ctgatggaaa
     9541 aaaattacgt aataaatatc cagaaataat agtaaagaca aaacagtttt tttttcatcg
     9601 catctcatca tttgttttaa atcaaactag tccattgata atctatgcct ttgctagtct
     9661 tacaatggta gcaatctatg gaaattatat gttgatagtt tttggtggaa tagctctggt
     9721 aaatgctttt tttaatggtt tcaatgctgg agtgggaaat cttgttgctg aaggagataa
     9781 gaaaaaaata aaatcttttt tttgggaaat aacttctttt cggatatgga tagcagccat
     9841 catttgtgtc tgttttttta agttgtgtca tccttttatt tcattgtggg tgggaaagga
     9901 atatgttttg gatgaaatga cctttatagt gttaactatt tatgttttta tatcattaac
     9961 aagagtaaat gaagcttttc tatttgctta tggattatat caggatatat gggctcctat
    10021 aattgaagct atattaaact tgggactttc ggttttattg ggatttattt ggggactaac
    10081 aggaataata tctggggttg ttattagttt agttgtcatt gtatgtatat ggaaaccata
    10141 ttttttattt aaaatgggtt tcaaagataa tatattagaa tatgtctcta gatatataaa
    10201 atattatatg atgattgctt tatcttttat tttgtcacat ttaattctta atacaatgtt
    10261 tatagacttc caaagttcat attggaagct ttttgaatat gcttgtactg ttggaagctg
    10321 ttatgctata ttgagttttc tcttttttta tttatttgat aatgggatga gacaatttac
    10381 tagacgttta ttaaatatat ttctaaaata atttagtgat aaggtgtagt tgttatattt
    10441 agtttttagc tgaaatagat tttgtcttgt attataaaaa atgagttttt atatatttat
    10501 ttttgttgtt ttgctgtatt tctcttttag gaaatataat aaatatattt attggggaac
    10561 tattttatta ctttcattga tagcagggtt gaggtccgaa acgataggag ttgatactca
    10621 cgcttataaa gatatattta tatggatatc aaatgaagta ttatatccga tagaacctgc
    10681 atggtatttt ttaaataaat tgattgcttg ggtgggggga agttttaatt tcttgttgtg
    10741 gataactgca ctattgactt taataccaat aggtgtagtt agtttacgat gtagcagtaa
    10801 tcctcagatg agtttgtttt tttactatgg attatatgca tatattaatt catttaatgg
    10861 aatgagacag tttgttgcta tttcatttgt attattagct tattcttata tcacacaaaa
    10921 gaagaatttt tttttgtatt tactaattgc attcatattc cattattcag cgattttttc
    10981 tttcattgct attttggtag ataaggtatc attaactaaa cgacgtgtaa ttggtggtat
    11041 tttttctagt ttttttgtag gtatgttttt taatgattct atgtttctag ttttggctgg
    11101 tccttatgca ggttatttag aatcttctga gggatatagg gataattttt tattggctgc
    11161 tataatggca attttgatga gttgtttata tatgtgtacg ttttttactt tacgaagaga
    11221 atataaacaa aatttgtgga caaaaatgtt ttttgttggc attattatat tgaatataac
    11281 tatgcggtta gaattaggag ctcgtattat tttgtatttc acattatgcc aaattatatt
    11341 ttacccaatg tatttccgtc ataatattgt caaaaataaa agaatggttg ttttgagtat
    11401 tttattgtat acttcgttgg tttttatgaa aatattaatt ttgggtaatc aaggagaata
    11461 ttctgtctat ccttataaaa caatattatg gtaagcatta ttattccttg ttacaattcg
    11521 ggaaaatata tttctgaatg tttaaattct attttagctc aaacatattc tgaatgggaa
    11581 gcaatttgtg ttaatgatgg tagtactgat aatacaatgg aatttctgaa tcaatatgta
    11641 atgtcggata atcgatataa agtagtttct cagcttaatt caggagtgtc agcagcaaga
    11701 aataaggctt tatctatatg caggggggaa tatatttgct ttgtagatag tgatgatata
    11761 gtagaacc
//
