LOCUS       c00045_gnlPro..        24675 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ECNEEKLO_88.
ACCESSION   c00045_gnlPro..
VERSION     c00045_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 10:59:58
            Original ID  :: gnl|Prokka|ECNEEKLO_88
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 146447
            Orig. end    :: 171122
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     cand_cluster    1..24675
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /detection_rules="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /kind="chemical_hybrid"
                     /product="Pyruvate2acetate-formate"
                     /product="GR_fatty_acids"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="gutsmash"
     region          1..24675
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Pyruvate2acetate-formate"
                     /product="GR_fatty_acids"
                     /region_number="2"
                     /rules="((PFL_acetate1 or PFL_acetate2) and Radical_SAM)"
                     /rules="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /tool="gutsmash"
     protocluster    1..22971
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[156447:159418]"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..12971
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="((PFL_acetate1 or PFL_acetate2) and
                     Radical_SAM)"
                     /neighbourhood="10000"
                     /product="Pyruvate2acetate-formate"
                     /protocluster_number="1"
     protocluster    743..24675
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[157189:161122]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_fatty_acids"
                     /protocluster_number="2"
                     /tool="gutsmash"
     proto_core      10743..14675
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [Gly_430_pcre, Gly_8-9_TMA,
                     Gly_radical, Gly_radical_scatole, PFL-like, PFL_6_pcresol,
                     PFL_9_tma, PFL_acetate1, PFL_acetate2, PFL_proline,
                     PFL_toluene]) and not NRDD and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (POR or POR_N or PFOR_II))"
                     /neighbourhood="10000"
                     /product="GR_fatty_acids"
                     /protocluster_number="2"
     CDS             4046..5350
                     /locus_tag="ctg45_117"
                     /transl_table=11
                     /translation="MRRVGHIIEEIVEPSNMEASFRQVLRGRKRKRSRQGCYLLAHKPE
                     VLEELTAQIASGTFRVKDYREREIVEGGKLRRIQVIPMKDRIAVHAIMAVVDRHLRKRF
                     IRTTSASIKKRGMHDLLAYIRRDMREDPEGTRYCYKFDITKFYESVKQDFVMYCVNRVF
                     KDFKLMAMLESFVRLMPDGLSIGLRSSQGLGNLLLSVFLDHYLKDRYAVRHFYRYCDDG
                     AILGKTKAELWKIRDAVHGHIQRVGLDVKENERVFPLDEGIDFLGYVTFGADHVRLRKR
                     IKQKFARKMHEVKSRRRRRELIASFYGMAKHADCHTLFKKLTGKDMRSFKDLNVAYKPE
                     DGKKRFPGVVVSIRELVNLPIVVKDFETGIKTEQGEDRCIVAIELNGEPKKFFTNSEEM
                     KNILSQVKEMPDGFPFETTIKTETFGKGRTKYVFT"
     CDS             5347..5832
                     /locus_tag="ctg45_118"
                     /transl_table=11
                     /translation="MKRVEGTAGVKLLECVNPVKNTWRVRWDVREREDGSADYMEENFL
                     GKPSGEIIRSVILGWYNEQIDREILSGFVYEGMPVWLSSENQFNYKAAHDLAVQNGGAT
                     LPVTFKFGTDEEPRYRTFGKLEELTDFYTKAMKHIQDTLADGWKKKDAFDPEKYRVE"
     CDS             6011..6253
                     /locus_tag="ctg45_119"
                     /transl_table=11
                     /translation="MKVIEILNFNRELLKRLQAAGIRLEDARYIDLYADYTRLLDQGEK
                     VSYAVAVLSKKYSVSERKVYALVKRFQSDCKTLAV"
     CDS             6326..6970
                     /locus_tag="ctg45_120"
                     /transl_table=11
                     /translation="MAMNKYYRILDKILVAGKTQTNKKGNIQYLLNEQLSLTPADLLDI
                     FEGHNIARKKLRSELQLFMQGERNVERYREAGINWWDYCGSILVNSYPTYFEKLPPLIA
                     KINREKRNSKNYVLFLGETGAESNQAPCLSLVQFQLDGGELVLSAYQRSSDANLGLPSD
                     IYHLYLMARQIELPLKSITLYLGNVHIYENNIPGTRALIAGDETVRFGLNV"
     CDS             7066..7920
                     /locus_tag="ctg45_121"
                     /transl_table=11
                     /translation="MRKMYLSAPLPFVGQKRMFAKEFIKVLGQFPDSTVFVDLFGGSGL
                     LSHITKCVRPDAVVVYNDFDNYRQRLANIPATNVLLSDLRRIAEGEPRNQRITGEVRDK
                     MFARIEREEKEHGYVDYITISASLLFAMKYVTCLKEMKKETIYNRIRRTDYPEAEDYLK
                     GITVTCEDYKEVFKRYKDVPGVVFLVDPPYLSTEVGTYKMYWRLADYLDVLNVLKGHAF
                     VYFTSNKSSILELCDWMGRNPFLGNPFKECRKVEFNASVNYNSKYTDMMLYTVQDEVTG
                     VAA"
     CDS             complement(8047..8331)
                     /locus_tag="ctg45_122"
                     /transl_table=11
                     /translation="MKHFTIFQGFYYAIAEMTEEEIVSTIGSFTYREKVEEIRRIFAEQ
                     GEKAANEKKKELPAIAFSASYLNPEKRNVPLYKNDAFQKVQKRRVPEKR"
     CDS             complement(8418..8648)
                     /locus_tag="ctg45_123"
                     /transl_table=11
                     /translation="MNYKEDSFLIRTYTKAELAHLYNPHVCLKVALQILRRWIIYNLPL
                     LHELEQEGYRARNRLLSPKQVATIIHFLGEP"
     CDS             8842..9345
                     /locus_tag="ctg45_124"
                     /transl_table=11
                     /translation="MAMTVSYSVVPRKNPAKKSEPAKYYAQAQASGELDFEELCEAITS
                     RSTCTETDVRAAISGILYEVKRALKAGRIARLGDLGSLQIGLNSEGAASVKEFSGSMIK
                     GAHLIFRPGKTLAELMKILSYQQVQTRAVAQAGAGDGGGEDPDKNPDSGGDGSGDEEAP
                     DPTV"
     CDS             9405..9572
                     /locus_tag="ctg45_125"
                     /transl_table=11
                     /translation="MKEIVSRILDVIMYLIPFFGKRKRDRVVREVRYHTTCKEVCKVKT
                     TEREKEHEKD"
     CDS             9559..10008
                     /locus_tag="ctg45_126"
                     /transl_table=11
                     /translation="MRKISLIVIHCSATRVDCDFTAKDVDTAHRYRGFSCWGYHYYIRK
                     SGEIEPMRDEDTVGAHARGYNAISLGVCYEGGLDENGKAADTRTPRQKEALHRLVHELL
                     QRYPEAKVVGHRDLSPDTNYNGIVDPWERIKECPCFEVIGEFSIN"
     CDS             complement(10001..10729)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: Radical_SAM"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1015:4Fe-4S single cluster domain (Score: 72.5;
                     E-value: 1.4e-22)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_127"
                     /sec_met_domain="Radical_SAM (E-value: 3.9e-28, bitscore:
                     92.6, seeds: 518, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMINVHSYESMGTFDGPGLRLVVFLQGCNFRCLYCANPDTIAGKG
                     GTPTPPEEIVRMAMSQRPFFGKRGGITFSGGEPTFQAKALVPLVRELKEKGIHVCLDSN
                     GGLWNEDVEELFRLTDLVLLDIKEFNPNRHQTLTGRSNEQTIRTAAWLEEQEKPFWLRY
                     VLVPGYSDFEEDIRALGEALGKYKMIQRVEILPYHTLGVHKYEAMGQEYKMKGVKENTP
                     EQLEKAAEVFKEYFTTVVVN"
     CDS             complement(10743..12971)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Pyruvate2acetate-formate: PFL_acetate1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: PFL_acetate1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: Gly_radical"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_128"
                     /sec_met_domain="Gly_radical (E-value: 1.3e-45, bitscore:
                     148.1, seeds: 99, tool: rule-based-clusters)"
                     /sec_met_domain="PFL_acetate1 (E-value: 0.0, bitscore:
                     1173.8, seeds: 10, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELNKIFKDGLWSSEINVRDFVSHNITPYYGDASFLEGPTERTKA
                     VWNRCLEALAEERENNGVRSLDNVTVSTITSHKAGYIDKENELIVGLQTDELLKRAIKP
                     FGGINVVSKACHENGVEVDDRVKDIFTHYRKTHNDGVFDVYTEEIRSFRSLGFLTGLPD
                     NYARGRIIGDYRRMALYGIDRLIEAKKEDLHNLTGPMTEARIRLREEVAEQIKALKDMK
                     VMGEYYGLDLSRPAYTAQEAVQWVYMAYLAAVKEQDGAAMSLGNVSSFLDIYLEYELSK
                     GTITESFAQELIDQFVIKLRMVRHLRMQSYNDIFAGDPTWVTESLGGRLNDGRTKVTKT
                     SFRFLQTLYNLGPSPEPNLTVLWSPELPEGFKEFCAKVSIDTSSIQYENDDLMREVRQS
                     DDYGIACCVSYQEIGKQIQFFGARCNLAKALLLAINGGRCENTGTVMVKNIPVLTSDTL
                     KFEEVMDNYKKVLTEIARVYNEAMNIIHYMHDKYYYEKAQMALVDTNPRINLAYGVAGL
                     SIALDSLSAIKYAKVTARRNDIGLTEGFDIEGEFPCFGNDNDKVDHLGVDLVYFFSEEL
                     KKLPVYKNARPTLSLLTITSNVMYGKKTGATPDGRAKGVAFAPGANPMHGRDKNGAIAS
                     LSSVAKLRYRDSQDGISNTFSIVPKSLGATDEDRIENLVTMMDGYFTKGAHHLNVNVLN
                     RDMLYDAMEHPENYPQLTIRVSGYAVNFVKLSREHQLEVISRSFHERM"
     CDS             13668..14675
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: Thiolase_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     GR_fatty_acids: ACP_syn_III_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ACP_syn_III"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_129"
                     /sec_met_domain="Thiolase_N (E-value: 8.6e-11, bitscore:
                     35.4, seeds: 30, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III (E-value: 3.6e-32, bitscore:
                     103.9, seeds: 136, tool: rule-based-clusters)"
                     /sec_met_domain="ACP_syn_III_C (E-value: 3.6e-34, bitscore:
                     110.6, seeds: 152, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKINAVITGVGGYVPDYVLTNDEISKMVDTTDEWIMGRIGIKER
                     HILNEEGLGTSYMARKAAKQLMQRTKSHPDDIDLVIVATTTSDYRFPSTASILCERLGL
                     KNAFAFDMQAVCSGFLYAMETGANFIRSGKYKKIIIVGADKMSSVIDYTDRATCPIFGD
                     GAAAFMLEPTTEEVGIMDSVLRTDGKGLPFLHIKAGGSVCPPSYYSLDHHLHYIYQEGR
                     TVFKYAVANMSDSCEAIIARNHLTKEDIDWVIPHQANQRIITAVAQRLEVPSEKVMVNI
                     ERYGNTSAGTLPLCIWDFEKKLKKGDNLIFTAFGAGFAWGAVYVKWGYDSKEDA"
     CDS             complement(14726..15202)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_130"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 9.8e-54,
                     bitscore: 174.9, seeds: 130, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSDIKLACDVVEQVKTICDKHGNNADELINILHEAQHLHGYLPEE
                     MQRIIASKLRIPVSKVYGVVTFYTFFTMTPKGKHPISVCMGTACYVRGSEKLLEEFKRV
                     LGIEVGETTPDGKYSLDCLRCVGACGLAPVVMIGEKVYGRLQPVDVKKIIEELE"
     CDS             complement(15221..16987)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer2_4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH-G_4Fe-4S_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_131"
                     /sec_met_domain="Fer4 (E-value: 1.7e-08, bitscore: 27.8,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00036, bitscore: 14.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_4 (E-value: 2.6e-22, bitscore: 72.5,
                     seeds: 126, tool: rule-based-clusters)"
                     /sec_met_domain="NADH-G_4Fe-4S_3 (E-value: 4.2e-18,
                     bitscore: 58.4, seeds: 418, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEEKQITLQIDGHFITVPEGSTILEAACKIGINIPTLCHIDLKGT
                     CIKNNPASCRICVVEVAGRRNLAPACATRCTEGMVVKTSTLRVMNARKVVAELILSDHP
                     NDCLTCPKCGNCELQTLALRFNIREMPFNGGELSPRKREVTSSIVRNMDKCIFCRRCES
                     VCNDVQTVGALGAICRGFNTTIAPAFDRMMKDSECTYCGQCVAVCPVGALTERDYTNRL
                     LDDLADPDKIVIVQTAPAVRAALGEEFGLPPGTLVTGKMVYALRELGFDYVFDTDFAAD
                     LTIMEEGSEILNRLTRYLDGDKSVRLPILTSCCPAWVNFFEHHFPDMLDIPSTARSPQQ
                     MFGSIAKSYWAEKMGIPREKLVVVSIMPCLAKKYECDRDEFKVNGVPDVDYSISTRELA
                     RLIKRANIGFTLVLDSPFDNPMGESTGAGVIFGTTGGVMEAALRSVYEIYTGQPLKNVN
                     FEQVRGLSGVRRATINLNGFELKVGIAHGLGNARHLLEDIRNGHNEYHVIEIMACPGGC
                     IGGGGQPLHHGNSDVLYARANALYREDANKPLRKSHDNPYIQKLYEEYLGKPLGEISEM
                     LLHTHYFNKSID"
     CDS             complement(16999..18906)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Complex1_51K"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fe-2S_thioredx"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NADH_4Fe-4S"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg45_132"
                     /sec_met_domain="Fer4_7 (E-value: 7.6e-10, bitscore: 33.1,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 7e-10, bitscore: 32.4,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 3.4e-50, bitscore:
                     163.6, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="Fe-2S_thioredx (E-value: 3.8e-11,
                     bitscore: 36.8, seeds: 130, tool: rule-based-clusters)"
                     /sec_met_domain="NADH_4Fe-4S (E-value: 8.2e-34, bitscore:
                     109.2, seeds: 645, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKILSIHDLQIIRKRAEHHLSLREESNEKVSEKCCGLASGTAHLQ
                     ILICGGTGCKASSSQGITENLQKAIERNGITDKVDVITVGCFGFCEKGPIVKIIPDNTF
                     YTQVTPEDAEEIISEHIIGGRRIERLLYIDPKTEQTVSDSKHMDFYRKQLRIALRNCGF
                     IDSENIEEYIAREGYFALADCLLNKQPADVIDVIKRSGLRGRGGGGFPTGLKWEFASKQ
                     VSDVKYVVCNADEGDPGAFMDRSIMEGDPHSIVEAMCICGYSIGSSKGLVYIRAEYPLA
                     INRLKKAIEQAREYGLLGDHILGTDFSFDIEIRYGAGAFVCGEETALIHSMEGKRGEPT
                     LKPPFPAESGYLGKPTNVNNVETLANIPIILTKGAEWFASIGTERSKGTKVFALAGKIN
                     NVGLIEVPMGTTLREVIYEIGGGIKGGKKFKAVQTGGPSGGCLTEKHLDTPIDFDNLLA
                     AGSMMGSGGMIVMDEDDCMVSVARFYLDFTVEESCGKCTPCRIGNKRLLELLNKITEGR
                     GTEKDLDTLATLGRVIKDTALCGLGQTSPNPVLSTLDNFRDEYLEHVRDKTCRAKQCKS
                     LLTYTINPELCIGCHLCAKNCPADAISGLVRKPHVINPEKCIKCGMCMARCKFKAILVC
                     "
     CDS             19488..22244
                     /locus_tag="ctg45_133"
                     /transl_table=11
                     /translation="MRRILLGLCVLFFLNAHGQEIPLPEKMPQDHPRVLTTPEGKKETW
                     KLIKKEAWAQDVFNKLKERTEVYTRRTESQPDWLLSRLAMYWKSHATEVYVKGEVFDHA
                     GGEKAPAPTVRYTGTRGTAATHGRPKLEDVVPYDDSAEGNVTFCNNALEGRPLESVHPS
                     KTGRNIESLNCEILGIARDAAFLYWMTGEEKYARLAAGVFDTYMTGIYYRNVPVDLNHG
                     HQQTLVGLTSFEVIHEDALHIVVPLYDFLYHYLQSNYPDKMMIYASALKKWADNIIANG
                     VPHNNWDLLQARYIMNVGLVLEDNKEYADGKGREYYIDYVMNRSSIRQWSLTKLADYGF
                     DSETGIWAECPGYSSVVINDYANFAHQFDHNLQYDLVKAMPVLAKAVATTPQYLFPNRM
                     ICGFGDTHPSYLSTNFFIRMIQNAQANGKKEQERYFTALLKCLNPEEGSEKSGKKNVRA
                     SVNSFFEDKPLVLDPKVEAGKIEDYVSPLFYAPNVSWLVQRNGMHPRNSLMISLNASEG
                     NHMHANGISMELYGKGYVLGPDAGIGLFLYSGLDYAEYYSQFPSHNTVCVDGISSYPVM
                     KSNHSFDLLSCFPASAEPGKGFTSVTYSQVAFREPESRADQTRLMGIVTTGPETGYYVD
                     VFRSRKERGGDKMHDYFYHNLGQTMTLTAADGTDLNLQPTEELAFAGAHLYAYSYLYDK
                     KVAATDQDVKVTFTIDMKDKGGDDISMNLWMKGEPEREVFTALAPMTEGLSRTPHMPYN
                     IKEQPTLTFVARQHGEAWNRPFVAVYEPSTQKEPSAIQSVSYFDAEEPGLKDFAGICVE
                     SKNGRTDHIFSLTDSSQTATYQGMKVKADYAVISNEYAGNRTLFIGNGTQLIASGISIQ
                     TSEAANVLLEKKQGKWYILSSAPCKMVIDGKAVQSGITTELTLLAVQ"
ORIGIN
        1 catcgacgtg ttcagcgcgg agaccgccga cggggagagc acctactacg ggcagtacaa
       61 cttcaacaac gagaagagca ggagcggtcg gctgttcggc atggaggggc ttgacggttt
      121 caccccttcc tgcccgatga cgctggagac gctgaacaac ggcgagaggg tctgcctttt
      181 ccagagctcc agcgacgcgg accttgccgc cggtttcgat gccggcctgg aaaccaacta
      241 cccggacgac gtgaaatggg ccggcctgaa cacgtcccaa cagtccgcgc tgaaacgcct
      301 tttcggctgg atccggtcat gtgtcccggc aaacgccacc gcggacgacc tggccacttt
      361 cgtgagcgaa aagttcagga cggaaatcgg gcagtatttt gacgtggacc acctgctgac
      421 ctactacgtg cataccgact acttcgcgag cgttgaccag cgcgcgaaga acatcctcct
      481 gcgtacctgg gacgggctgg tctggtatac cacctactac gacggtgaca cccagcttgc
      541 caagaggaac gactgtttcc ttgcctacga ctacacgatc gaccgtgaca cgtgggacgc
      601 ggaggccggg aaatacgcct tcgagggccg cgatagctgg ctttggaacc tcgtgctggc
      661 caacttgcag gacgagctga aagcctgcgc cgccgcttac cgcgcgaaaa tgacggtcga
      721 gcgcgtgctg tcgatgcttg acgtggaaca ggcgggcaac tggagcgacc gggcgtacaa
      781 caagagcggt tacctgaagt atatccgccc gaacatggaa gaggtttacg gcaaaaagtg
      841 gccgtttatc tacgccctcc agggaagcaa cgcggcgcac cgcagttact tcgtgaagaa
      901 ccgttttgcc cttttggacg ccaaatacgg cacgagcaac ttcacgagtg acaacatcga
      961 cctgtatatg gcccgtgcct cctccgatgc cgccgacgtg gtgaagatca cggcgagtga
     1021 ggtgtacgct ttcggttacg gcacgaacaa cagccccaat atcgggggta ccggcatcgt
     1081 ggagggcggc aaggtggcca cccttcaaat cacgggggcc tacacggtaa acgaccccct
     1141 gcgtatctac ggcgcgagcc gcatgcgtgt gcttgacatg accggcgcct cggaccgcct
     1201 gaagaacggc tttgacctgg gtaaatgtat cgtattgcgt gagctgaacc tgcaaagccc
     1261 ctccaccggc tcgacgggct ggtggctgaa catcggcagc tgccgccagc tgcgtaaggt
     1321 gaacctgcgc aaccaggcac aggccaagac cgggagcaac accagtaccg agcttgactt
     1381 tacgaaccag accaagctgg aggaacttga cgcgagaggc acgcaggtgc agagcgtgac
     1441 cttcgccaag ggtgccccgc tgacgagggc ctggcttccc ggcacgctga ccgtgttgaa
     1501 gctggaatac ctgggcaaac tggccacaag cgggctcacg ctggagaact acagtaaagt
     1561 gaagacgctt atcgttgacg gctgcccggg tctgaactgg gaaaccctgc tgaaccgctg
     1621 ttccggcgtg gaacgcatcc gtgtgaccgg catcgaccgg gaagacgacg gtacgtggct
     1681 gaatcggttc atgaagatgg gcggcgtgga cgcagaaggc aacgccacgg acacgtgcgc
     1741 gctggcgggt acggtgcgcc ttaccaacta tgtcgaggat gagagatacg aggcgttgaa
     1801 agcccatttc ccggaattga acatcctcca gcccgaatac acgatgatcg agtccgacga
     1861 tgatgtggcc gacgacgcca atatcagcaa cccggacaac aggacaggtt acaagtacgg
     1921 tacgccttac aggacgagtg ggcatatcgc cgccatcctg aaacagcgtt accgtgtact
     1981 ggcgaaagtg accaggaagc ctaccacgcg cagcgtgaag atcgcgaatg tcgatacgac
     2041 ggtgaacaac cttgacggcg agatgaccta ttacccgctg gacgacggca attccaaccg
     2101 ttacgccgac ggcagcgccg ccagacttga cggcagcgag ggcgactgga tgatgttcga
     2161 gccgtttttc tggtcaaagg gcatcaatga ctacctgaac ggcaagcatt actcctgcta
     2221 cagcagcaag ggccgggacg acatgccctc cgtccctgac gccgatatcc tcacgctgga
     2281 tgacatcaag gaagccggcg gctacctgag cggtcgtaag atcatgagcg gcaaggacac
     2341 gcttgcgaac agttacagtg ccgacaccac gtattccgtc tgcaaggtga acgtcagtgg
     2401 tcacaagcgt gtccggttcc cgagcgttcc cggtacgaac cttgtcggca gcgtgttcac
     2461 tgacaatgcc ggtaccgtag tcagttccat cgttgttccg accctctcca acaagttcga
     2521 ggcgggcatg tacctgatcg ctgacgttcc tgccggtgcc acagcgctgc acttctccgt
     2581 tctgaacacc gcggagttcg acaaggtagt gctttccaat tccgacagga tcgaggacat
     2641 ggagccggac tgggtagcca atgacgagca cctttgcgcg gtcgtgggca gttcggtcgt
     2701 cggttccaag ctccgcgcct gtatcaccgg cggcagcacc acggcgagca tgagctgggc
     2761 cgacttccat tattactcgg tacagcgcgg catgcagcag attgacgcgc tgatgcactc
     2821 ccgtatcgcc aacctcttct acgccgccta tggccgtcgt gacagtcagg aacaatgcgg
     2881 cgcgggccag catactaaca gccgtatcac cggcggtacc gcttcacgcg gcatgaccga
     2941 tacgatcggt tatgaagagg cgcacgccat caacccgaac gtgacgaatt cgcttgtgga
     3001 cgacatggtc caccagtacg cctggtaccg gggcgaggat gactacggcg gtgctactgt
     3061 cacgcaggtg aacaatatct gttgtcttgg ctacgaggat atctacggtc ataagtatga
     3121 catgatggac ggtgttgatc ttcctaatga cagcggcaac gccggcaagt ggcgcatctg
     3181 gatgcctgac ggcacgaccc gcatggtgaa agggggtaca ggttcgggcg tatggataac
     3241 ggccgttgca catggcaagt acatggacgt ggttccggtg ggctccgttt cgggttcttc
     3301 ctcgacgcat tactgcgata tgtactacat atctaccgca gccagccgtg tggtttatcg
     3361 tggcagccac agcgcgagcc cgaatggcgg tgtctcgatg tcgggtgcga attccgattt
     3421 ctcgaatacg tacacgagcg tcggttctcg tctggccttc cgcggccggc tcgtcaaggc
     3481 ggcgagcgtc gctgcgttca agtcgataag cgaggtggca tgatcggtcg cgtaaagcgt
     3541 caaagcggga gcgaagcgac gaaacgtccg gtgttcccct tgttcgggga acaccgttct
     3601 ttacgggcgt cagcccgttg aaaaattttt gtttccgggg ttttgtacct gtttgttaaa
     3661 taataattta tgaaaaatcg tacttttgca ttcaagttaa aaggtggcgc ttccccataa
     3721 gccgtgtggt ttatcgtggc aacaacaacg cgaacccgaa tggcggtgtc tcgatgtcga
     3781 atgcgaataa cgatttctcg aatacgaaca cgaacgtcgg ttctcgtctg aacaacaatc
     3841 gaaaaggaat tttaatcggc gtacaacacc ggggacttgt ccccatcgtg gtgccgaggg
     3901 aagcaagcct cagtaacagc agccttttcg gggctggaaa actgaaaaat agagtgtcgg
     3961 gtagggtttg gtaggccgga aacggttcga agaagccggg cccgggggat tgaaggcccc
     4021 gtattaaaaa caagaaaagg tatttatgcg cagagttggt catatcatcg aggagattgt
     4081 ggagccttcc aacatggagg cctcgttccg gcaggtcctt cgcggcagga aacgtaaacg
     4141 cagccgccag gggtgctatc tgcttgcgca taagcccgag gtattggagg aactgaccgc
     4201 gcaaattgca tccggcactt tccgggtgaa ggactaccgt gagcgtgaga ttgtggaggg
     4261 cgggaaacta cgccggattc aggtgatccc gatgaaggat cgtattgccg tgcatgccat
     4321 tatggcggtg gtggaccgcc atttgcggaa acgtttcatc cgtactacct ctgccagtat
     4381 caagaaacgg ggaatgcacg accttctggc gtatatccgt cgtgatatgc gtgaggatcc
     4441 ggaaggtacg cgttactgct acaagttcga tatcacgaag ttctacgaga gtgtgaaaca
     4501 ggatttcgtg atgtattgcg tgaaccgggt tttcaaggac ttcaaactta tggccatgct
     4561 ggagagtttt gtccgtctga tgcccgatgg tttgagtatc gggctacgca gctcgcaggg
     4621 tctgggtaat ttgcttttgt ctgtgttttt ggaccattat ttgaaggaca ggtatgccgt
     4681 ccgtcatttc taccgttatt gtgatgacgg cgctatactg ggtaaaacga aagcggaatt
     4741 gtggaagatt cgtgatgccg tccatgggca tattcagcgg gtcggtctcg atgtgaagga
     4801 gaacgagcgc gtgtttcccc tggacgaggg catcgatttt ctggggtatg tgactttcgg
     4861 tgcggaccac gtccgcctgc gcaagcgcat caagcagaaa ttcgcccgaa aaatgcacga
     4921 ggtaaaatcg agaagaagga ggcgtgagct gatagcgtcg ttctacggga tggccaagca
     4981 cgccgactgt catacgttgt ttaaaaaatt aacaggcaaa gacatgagat catttaaaga
     5041 cttgaacgtc gcttataagc ccgaagacgg caaaaagcga tttcccgggg tggtggtaag
     5101 catccgggaa ctggtaaact taccgattgt agtgaaggac ttcgagacgg gcatcaagac
     5161 cgagcaggga gaagaccgct gtatcgtggc catcgagctg aacggcgagc cgaagaagtt
     5221 cttcaccaac agcgaggaga tgaagaacat cctctcgcaa gtgaaagaga tgcccgacgg
     5281 ctttcctttt gaaacaacca tcaagacgga aacctttggg aaaggtcgaa ccaaatacgt
     5341 atttacatga aacgagttga aggaacagcc ggggtgaagc tgctggaatg cgtgaacccg
     5401 gtgaagaaca cgtggcgcgt ccgttgggac gtgcgggaaa gggaggacgg ttctgccgac
     5461 tatatggagg agaacttttt agggaagccc tccggtgaga taataagaag cgttatcctg
     5521 ggctggtaca acgaacagat cgaccgggag atactttccg gcttcgttta cgagggtatg
     5581 ccggtgtggc tgtcaagcga gaaccagttc aactataagg cggcccacga ccttgccgtg
     5641 cagaacggcg gcgcgacgct tccggtgacg ttcaagttcg ggacggatga ggagccccgg
     5701 taccggacgt tcgggaaact ggaggaactg acggacttct atacgaaagc catgaagcac
     5761 atccaggata cactggctga cggctggaaa aagaaagacg cttttgatcc ggagaagtac
     5821 cgggtggaat aaatccttcg ggggaggata agaaaaaagc ccccggcctg ttaaaaagta
     5881 acgccaatca cttttataaa catgaaacgc caaaccgcgc gaccgggggc aaataccctc
     5941 tgtcacggtt tgacgttttt ttgttgtcta aaaaatgatt ggcgatgcaa agatataatt
     6001 tttttgttgt atgaaagtga ttgagatact aaactttaac cgggagctgt tgaaaaggct
     6061 ccaggcggcc ggcatccgtc tggaggatgc ccggtatatc gacctgtacg cggactatac
     6121 ccgtctgttg gaccaaggtg agaaggtctc gtatgccgtg gccgtactgt ccaagaaata
     6181 ttcggtgagc gagcgcaagg tttatgcctt ggtaaaacgc ttccagagtg actgcaagac
     6241 gcttgcagtg tgaacggggt gttttatgcc gtagggagtg ccgtttcccc ttatctttag
     6301 ggtgtttcaa ttttagaagg aggaaatggc tatgaacaag tattaccgta tcctggacaa
     6361 gattcttgtc gcgggaaaaa cacagaccaa caagaaggga aacatacaat accttctgaa
     6421 cgagcagctg tcgctgacac cggcggactt gcttgacata ttcgaggggc ataatatcgc
     6481 ccgcaagaaa ctccgcagcg agctccagct gttcatgcag ggggaacgaa acgtggagag
     6541 gtaccgggag gctggcatca actggtggga ttattgcggt tccatcctgg tgaacagtta
     6601 ccccacatat tttgagaagc tgccgccgtt gatagcgaaa atcaaccggg agaaacgcaa
     6661 cagcaagaac tacgtgcttt tcctgggtga gaccggtgcg gaaagcaacc aggcgccctg
     6721 cctgagtctg gtacagttcc agctggatgg tggtgaactg gttctgtccg cctaccagcg
     6781 cagcagcgat gcgaacctcg ggctgccttc cgacatttac cacctgtacc tgatggcccg
     6841 gcagatagaa cttcccctga agtcgatcac cctctacctg ggcaatgtac atatctacga
     6901 gaataatatc ccgggtacac gtgcgttgat cgccggtgac gagacggtcc gcttcgggct
     6961 gaacgtgtga tttgctgtat atgccttgca gcgggaacag ttcatttttc ccgctgtttt
     7021 tcgtttattc tggggacctt tgcggccgtt ttaaagcaga atgaaatgag aaagatgtat
     7081 ttgtccgccc cgcttccttt cgtggggcag aaacgcatgt ttgcgaagga gtttatcaag
     7141 gtgctggggc agttcccgga cagcaccgtg tttgtggacc tgtttggcgg ttctggcctg
     7201 ctgtcacata ttaccaaatg tgtcaggcct gatgccgtcg ttgtgtataa tgacttcgac
     7261 aactaccgcc agcggcttgc gaatatcccg gccaccaatg tgctgctatc cgatttgcgc
     7321 cggatagctg aaggggaacc cagaaaccaa cgtataaccg gggaggttcg cgataaaatg
     7381 tttgctcgta ttgagaggga agagaaggag cacggctacg tggattatat tacgatttcc
     7441 gcatctttgt tgttcgccat gaagtacgtg acttgtttga aagaaatgaa gaaagagacc
     7501 atctacaata ggattcggag gactgattat cccgaagcgg aagattacct gaaaggaatt
     7561 accgtcacct gtgaggatta taaggaagta ttcaaacgtt ataaggatgt tccgggcgtg
     7621 gtgttcctgg tcgatccgcc gtacctttcc actgaagtgg gaacctacaa aatgtattgg
     7681 cgcctggctg actatttgga cgtgttgaac gtgctgaaag gacatgcgtt cgtgtacttc
     7741 acctcgaata agtcttccat cctggaactg tgtgactgga tggggcggaa cccgtttctt
     7801 ggcaacccgt tcaaggaatg tagaaaggtg gagttcaatg caagcgtgaa ctataactcc
     7861 aagtacacgg acatgatgct atacacggta caggatgagg tgacaggtgt ggcagcctga
     7921 tactgtatga agatagtaaa ttgttttgaa ccggcaatgg cttttgaatg atattttaaa
     7981 accgttcaaa gggtgttcaa acgaaaagga aacggtgggc tctggtcatg caggacagga
     8041 ccgggctcac cgtttttctg gtacgcgtcg tttttgtact ttttgaaacg cgtcgttttt
     8101 gtaaagtggc acgtttcgtt tttccggatt taggtagctg gcggagaagg cgattgccgg
     8161 caattctttt ttcttctcat tggcagcctt ttctccttgc tctgcaaaga tgcggcgtat
     8221 ttcttcgact ttttcccggt aggtaaaact gccgatagtg gacactattt cttcttcggt
     8281 catctctgct attgcgtagt agaaaccttg aaatatggtg aaatgtttca tttttatttt
     8341 gattattgtt tgtcgatgca aaggaacttc tttgcggaaa tgtgtaaagg aactttgtat
     8401 aaaatggcaa taagttacta cggttcgccc aaaaagtgta tgatagttgc cacttgtttc
     8461 ggcgaaagga gacggttgcg tgcgcggtag ccttcctgtt cgagttcgtg caggagaggg
     8521 aggttgtaaa taatccaacg acgaagtatt tgtaaagcaa ctttgaggca gacatgggga
     8581 ttgtaaaggt gagccagttc cgctttggta taggtgcgga taaggaaaga atcttctttg
     8641 taattcatga tgttttcttc ttgttttatg ctataaagtt acataaaatt ccttgttatt
     8701 caaaggtttg acttcgtttt tattcgttgg gaatcaagaa acttcgttgg ggaatatggc
     8761 ttgtccggct atccttatct ttgtgctgtt aacaagaagg ggatgcatcc tatgtattat
     8821 aaactttaaa attattttat tatggcaatg acagtatctt attcagtggt gccgcgcaag
     8881 aatcctgcaa aaaagagcga accggcaaag tattatgcac aggcgcaggc gtcgggagag
     8941 ttggactttg aagagttgtg cgaagcgatc accagtcgtt ctacttgtac ggaaacggat
     9001 gtacgtgcgg ctatttcggg tattctttac gaagtgaagc gtgcgttgaa ggcaggaaga
     9061 attgcgagac tgggcgattt gggcagtttg cagataggac tcaacagtga aggtgcggca
     9121 tcggtcaagg aattttccgg ttcaatgatt aagggggcgc atcttatttt ccgccccggt
     9181 aagacgctgg cggagttgat gaagattctg agttatcagc aagtgcagac tcgtgcggtg
     9241 gcgcaggcgg gtgcaggcga tggcggggga gaagaccctg acaagaatcc ggattccggt
     9301 ggtgatggct ccggtgatga agaggctccg gaccctacgg tataattggc agacgggtca
     9361 aggtaataac gaattagaat aacttccatt aatattttga taagatgaaa gaaatagtaa
     9421 gtcggatttt agatgtgatc atgtatctga ttcctttctt cggaaagaga aagcgggaca
     9481 gggtggtgag agaagtgcgc tatcatacta cttgtaagga ggtgtgcaaa gtgaaaacga
     9541 cggaaaggga aaaggaacat gagaaagatt agtctgattg tgatccattg ttccgccacc
     9601 cgtgtcgatt gcgactttac ggcaaaggat gtggatacgg ctcaccgtta tcgtggcttt
     9661 tcgtgctggg ggtatcatta ttatatacgc aagtcgggcg agattgagcc gatgcgggat
     9721 gaagatacgg tcggagctca tgcacgtggc tataatgcga tcagcttagg tgtatgttat
     9781 gagggcggtc tggatgagaa tggaaaagct gcggatacgc gtacaccccg tcagaaggag
     9841 gcgctacatc gcttggtaca cgaattgttg cagcgttatc cggaagctaa agtagtaggg
     9901 catcgggatt taagtcccga caccaactat aatgggatcg tagatccttg ggaacggatt
     9961 aaagaatgcc cttgctttga ggtcattgga gaattctcca ttaattaact accaccgtag
    10021 tgaaatactc tttgaatacc tccgcagctt tttcaagctg ttcgggggta ttttctttta
    10081 cccctttcat cttgtattcc tgtcccatcg cttcgtactt atgtacgccc agtgtatggt
    10141 aaggcagtat ttccacccgt tggatcatct tgtattttcc gagtgcttct cccagtgcgc
    10201 gtatgtcttc ttcaaaatcg ctgtatccgg gcactagcac gtagcgtagc cagaaaggtt
    10261 tctcctgttc ttccagccag gcggccgtgc ggatggtttg ctcgttgctt cttccggtga
    10321 gcgtctgatg gcggttgggg ttgaattcct ttatatccaa taacacaaga tcggtcagtc
    10381 tgaataattc ttctacgtct tcgttccaaa gtcctccgtt gctgtccaga cagacatgga
    10441 tgcctttttc tttcagttcg cggaccagcg ggacgagtgc tttcgcctga aacgtcggtt
    10501 cgcctccgga gaaagtgatt ccccctcgtt tcccgaagaa ggggcgctgg ctcattgcca
    10561 tgcggacgat ttcttccggt ggggtaggcg tgcctccctt tcctgctatc gtatccggat
    10621 tggcgcaata gaggcagcgg aagttgcatc cttgaagaaa aacgacgagc cgtaagcccg
    10681 gcccgtcgaa tgttcccata ctttcgtatg aatgtacgtt tatcatcata tagagtaata
    10741 gattacatac gttcgtggaa gctacggctg ataacttcca gttggtgttc gcggctcagc
    10801 ttcacgaagt ttacggcata gccggaaacg cggatagtca gctgcggata gttttccgga
    10861 tgctccatgg catcgtacag catatcacgg ttcagtacgt ttacgttcag gtggtgggca
    10921 cctttggtga agtaaccgtc catcatcgtc acgaggttct cgatacggtc ttcgtccgta
    10981 gcacccagtg atttcggaac gatagagaag gtgttgctga taccgtcctg tgagtcacgg
    11041 taacgaagtt tcgctacaga actcagagaa gcgatcgcac cattcttgtc gcgtccgtgc
    11101 atcggattgg cacccggagc gaaggcaaca cctttggcac gtccgtcggg agtagcaccg
    11161 gtctttttgc cgtacatcac attggaagtg atagtcagca aggagagggt aggacgggca
    11221 ttcttgtaaa caggcaattt cttcaattct tcgctgaaga agtataccag gtctacgcca
    11281 aggtggtcta ccttgtcgtt gtcgttaccg aagcaaggga attctccttc gatgtcgaag
    11341 ccttctgtca gaccgatatc attgcggcgg gcagttactt tcgcatattt gatggcagac
    11401 agtgaatcga gggcgatgga aagtccggct acaccgtaag ccaggttgat gcgcgggttc
    11461 gtatctacaa gagccatctg ggccttctcg tagtaatact tgtcgtgcat atagtggatg
    11521 atgttcatcg cttcgttata tacgcgggcg atttcggtca gcactttttt gtagttgtcc
    11581 attacttctt cgaacttcag cgtgtcactg gtcagtacgg ggatgttctt caccatgact
    11641 gtaccggtat tctcgcaacg tccgccgttg atggcaagca acagggcttt ggccaggttg
    11701 caacgggcgc cgaagaactg aatctgcttg cctatttcct ggtatgatac gcagcaggcg
    11761 attccgtagt cgtcggactg acgtacttcg cgcatcaggt cgtcattttc gtactggata
    11821 gaagaagtgt cgatagaaac ctttgcacag aattctttga atccttccgg aagttccggg
    11881 ctccagagta cggtcaggtt cggttccggt gaagggccga ggttgtacaa tgtctgcagg
    11941 aaacggaagg aggtctttgt cactttggta cgtccgtcgt tgagacgtcc gcccagagat
    12001 tcggttaccc aggtcgggtc gcctgcaaag atgtcgttgt atgattgcat acgcaggtgg
    12061 cggaccatac gcagtttgat gacaaactgg tcgatcagct cttgcgcgaa tgattcggtg
    12121 atggttcctt tgctcagttc atattccaga tagatatcga ggaaagaaga aacgttaccc
    12181 agtgacatag cggcaccgtc ttgttctttg acggcggcaa ggtaagccat atatacccac
    12241 tgtacggctt cttgtgccgt gtaagcggga cggctcaggt cgagaccgta gtattcgccc
    12301 atcactttca tgtctttcag tgccttgatc tgttctgcca cttcttcgcg caggcggatg
    12361 cgggcctctg tcatcggacc ggtgaggttg tgcaaatctt ccttctttgc ttcgatcaga
    12421 cggtcgatgc cgtaaagagc catacggcgg tagtcaccga tgatgcgtcc gcgtgcataa
    12481 ttgtcgggaa gtccggtaag gaatcccagc gaacggaagg aacggatttc ttccgtatat
    12541 acgtcgaata ctccgtcgtt gtgcgtcttg cggtagtgag tgaaaatatc ttttacgcgg
    12601 tcgtccactt ccacgccgtt ttcgtgacag gctttgctga ctacgttgat acctccgaaa
    12661 ggcttgatgg cacgtttcag aagttcgtct gtctgcaggc cgacgatcag ttcgttttcc
    12721 ttgtcgatat atccggcctt gtgggaagtg atggttgata cggtaacatt atctaatgag
    12781 cggacaccgt tgttttctct ttcttctgcc agtgcttcga ggcagcggtt ccatacggct
    12841 ttggtacgtt ctgtaggtcc ttcgaggaat gaagcatctc cgtaatacgg agtgatgtta
    12901 tgacttacga aatctctgac gttgatttcg ctgctccaaa gaccgtcttt aaagatcttg
    12961 tttaattcca taaaatgata aaattagagg ttgtagttat cctattcttt agagcgcaca
    13021 aagttacaat catttttcat ataatcagca taaatatgct ctattttatg cttttcaaca
    13081 taaaatacct attaattgct atccttagga aaagattaga ttaaattttt agtgaaaact
    13141 cttgcaagtt taaaatatct tcgtaccttt gcaccgcttt taacgaaaag cacttctgat
    13201 aaggaagttt tggagaggtg gcagagtggt cgattgcggc ggtcttgaaa accgttgtac
    13261 cgcgaggtac ccggggttcg aatccctgtc tctccgctga aaagcagctt ttgggctgct
    13321 tttttgtttt tatggagggc gacacctccg atgtcgtgaa acgaaaacgg gagcgttttc
    13381 ttagtgttta ttgagttttt tgaaaggaga gatgctcgag tggttgaaga ggcacgcctg
    13441 gaaagcgtgt atacgccaaa agtgtatcgc gggttcgaat cccgctctct ccgctgaatc
    13501 tgaaatttag tcaaaacttc tcgttcttta gccaaaagtt cttttcatag gtcaaagtgt
    13561 ctggtatttc tagtactctt ctcttgtata tcattctctt ttctgtatat ttgcgcccga
    13621 tatttttttt gagatatcac atatttgtaa ttctgaaaat agacttgatg gataaaataa
    13681 atgcggtaat tactggggtc gggggatatg tgcccgatta tgtgctgact aatgatgaaa
    13741 tttctaaaat ggtggatacc accgacgaat ggatcatggg gcgtatcggc ataaaagaac
    13801 gacatatctt gaatgaagag gggcttggaa cttcgtatat ggcccgtaag gccgccaagc
    13861 agttgatgca acgcacaaag agtcatcccg atgatatcga tctggtcatt gtcgccacta
    13921 ctacttcgga ctatcgtttt ccttcaacgg catctatctt gtgcgaaaga ctgggcctga
    13981 agaatgcttt cgctttcgat atgcaggcgg tttgcagcgg ttttctgtat gcgatggaaa
    14041 cgggagcgaa ttttatccgt tcggggaaat ataaaaagat tattattgta ggtgctgata
    14101 agatgtcgtc cgtaatcgat tatacggacc gtgccacttg ccctatcttt ggcgacggtg
    14161 cggccgcttt tatgctggaa ccgactacgg aagaggtcgg catcatggat tcggtgttga
    14221 gaacggatgg taaagggctg ccttttctgc atataaaagc gggaggttcc gtatgtcctc
    14281 cttcctatta ttcattggat catcatctgc attatattta tcaggaaggc cgcacggtgt
    14341 tcaagtatgc cgtagcgaat atgtcggatt cctgtgaagc tattatcgcc agaaaccact
    14401 tgactaagga ggatattgat tgggtgattc cccaccaggc taaccagcgt atcattaccg
    14461 ctgtggcgca acggctggaa gtaccgtccg agaaagtgat ggtcaacatc gaacgttatg
    14521 gcaacaccag tgccggcacg cttccacttt gcatctggga ttttgagaaa aaactgaaga
    14581 aaggcgataa tctgatattt accgcattcg gtgcgggatt tgcctgggga gcggtttatg
    14641 tgaagtgggg atatgactcc aaagaagatg cgtgacatat cgggtacccg atacgtcaca
    14701 tcctcttttg aagggcgggg gagacttatt ccagttcctc gataatcttc tttacatcca
    14761 ccggttgcag tcgtccgtac accttttcgc cgatcatcac taccggagcc agtccgcagg
    14821 cgcctacgca gcgcaggcaa tccagcgaat actttccgtc gggggtggtt tctccgactt
    14881 cgatgccgag tacccgcttg aactcttcca gcaacttctc cgaaccacgt acgtagcacg
    14941 ccgtgcccat gcagacggaa atcggatgct ttcctttggg agtcattgta aagaaggtgt
    15001 agaatgtcac aactccgtag actttcgaca cggggattct gagtttggag gctatgatcc
    15061 gttgcatctc ttcgggcaga tagccgtgca gatgttgcgc ttcatgcaaa atattgatta
    15121 attcgtccgc attgttcccg tgtttgtcgc aaatcgtctt gacttgttcc accacatcgc
    15181 aggctagctt gatatctgac ataatagtac ttgtttaaag ttaatcaatc gatttgttga
    15241 aataatgcgt gtgcaagagc atttccgata tctcacccag cggtttgccg agatattctt
    15301 catacagttt ctgaatatag gggttgtcgt gagatttgcg cagaggtttg ttggcatctt
    15361 cccggtaaag ggcgttggca cgggcgtaga gaacgtccga gttgccgtga tgcaagggtt
    15421 gcccgccacc tccgatgcag ccgccggggc atgccatgat ttcgatgaca tgatattcat
    15481 tatgtccgtt tcgtatatct tccagtaagt gccttgcgtt gcctagtccg tgtgcgatgc
    15541 ctactttcag ttcaaatccg ttcaggttga tggtggcgcg ccggacaccg ctcagtccgc
    15601 gtacctgttc aaagttgaca ttcttcagcg gctgtccggt gtagatttca taaacggagc
    15661 gcagggcggc ttccatgaca ccacccgtcg taccgaagat gacaccggcg ccggtcgatt
    15721 ctcccatagg gttgtcgaac gggctgtcca gcacgagggt aaagccgatg ttggctcgct
    15781 ttatcaggcg tgccagttcg cgggtggaga tggagtaatc gacatcgggg acaccgttta
    15841 ctttgaactc gtcgcggtca cattcatatt tcttggccag gcagggcatg atggagacga
    15901 ctaccagctt ttcgcggggg attcccattt tctctgccca gtaagacttg gcgatagagc
    15961 cgaacatctg ttgtggagaa cgggcggtag aagggatatc cagcatatcc gggaagtggt
    16021 gctcgaagaa gtttacccaa gccgggcagc aggaagtcag gatcggaagc cggacggatt
    16081 tatctccgtc cagatagcgt gtcagtcggt tcaggatttc ggaaccttct tccatgatgg
    16141 tgaggtcggc ggcaaagtcg gtatcgaata catagtcgaa acccagttcg cggagggcgt
    16201 aaaccatttt tccggttacc agtgtgccgg gaggcaagcc gaattcttct cccagggcgg
    16261 cacgtacggc gggggcagtc tggacaatta cgatcttatc ggggtcggcc aaatcgtcca
    16321 gaaggcggtt ggtgtaatcc cgttcggtca gtgcgcctac cggacatacg gctacgcatt
    16381 gaccgcagta ggtacattcg ctgtctttca tcattctgtc gaaggcaggg gctatcgttg
    16441 tgttgaatcc gcggcagatg gctcccagtg cgccgactgt ctgtacatcg ttgcagacgc
    16501 tttcgcatcg gcggcagaag atacacttgt ccatgttgcg cacaatggag gaggtcactt
    16561 cccgtttgcg gggagaaagt tcgccgccgt tgaacggcat ttcacggatg ttgaaacgca
    16621 gtgccagtgt ctggagttca cagttgccgc atttggggca ggtgagacag tcgttgggat
    16681 gatcggacag gatcagttcg gctaccactt tccgggcgtt catcacgcgt agggtactgg
    16741 ttttcactac catcccttcc gtgcaacggg tagcgcaggc gggagccaga ttgcggcgtc
    16801 ctgccacttc gactacacag atgcggcagg aagcgggatt gttcttgata caggttcctt
    16861 tcaggtcgat gtgacacagc gtaggtatgt tgatgccgat tttgcaggcg gcttcgagga
    16921 tcgtgcttcc ttcgggtacg gtgataaagt gaccgtctat ctggagggta atttgttttt
    16981 cttccatagc agtagatttt agcagacaag aatagctttg aatttacagc gtgccatgca
    17041 catgccgcac ttgatacatt tctcggggtt gatgacatga ggtttgcgta ccaagccgct
    17101 gatggcatcc gccggacaat tcttggcaca taggtggcaa ccgatacaaa gttccggatt
    17161 aatggtatag gtcagcaggg acttgcattg tttggcgcgg caggtcttgt ctctgacatg
    17221 ttccagatat tcgtcacgga agttgtcgag ggtagacaac accggattcg gggacgtctg
    17281 tcccagtccg cagagtgccg tgtcttttat cacccgtccg agggtggcaa gcgtgtccag
    17341 gtctttttcc gtgccccgtc cttccgttat cttgttcagc agttccagca ggcgtttgtt
    17401 gccgatacgg catggggtac atttaccgca ggattcttcg acggtaaagt cgagatagaa
    17461 acgggcgacg gataccatac agtcatcttc atccatcacg atcatgcctc ccgatcccat
    17521 catggaaccg gctgccagca ggttgtcgaa gtcgatggga gtatccagat gtttctccgt
    17581 cagacagccc cccgacggac cgcctgtctg tacggctttg aatttctttc ctcccttgat
    17641 gcctccgccg atttcgtaga ttacttcccg cagggtagtt cccatcggta cttcgatcag
    17701 tccgacattg ttgatctttc cggcaagagc gaagactttg gtgcctttgg agcgttctgt
    17761 tccgatggag gcgaaccatt cggcgccttt ggtcaggata atgggaatat tggcgagggt
    17821 ttccacattg ttcacattgg tcggtttgcc cagataaccg gattcggcgg ggaaaggagg
    17881 tttcaaggtc ggttctcccc gtttgccttc catcgagtgg atgagggcgg tttcctcgcc
    17941 gcagacgaac gcgcctgctc cgtaacggat ctctatgtcg aagctgaaat ctgtccccag
    18001 gatgtggtct cccagtaatc cgtattcacg ggcttgctca atcgcttttt tgaggcggtt
    18061 gatggccagc ggatattcgg cgcggatgta gaccagtcct ttggaggaac cgatggagta
    18121 accgcagatg cacatcgctt ctacaataga gtgcgggtcg ccttccatga tggagcggtc
    18181 catgaaggcg ccggggtcgc cttcgtcggc gttgcagaca acgtacttta cgtccgatac
    18241 ctgcttactg gcaaattccc atttcaagcc ggtggggaaa ccgcccccac cgcgtccccg
    18301 caggccggag cgtttgatga cgtcgatgac gtcggcaggc tgtttgttga gaaggcagtc
    18361 ggccagtgcg aagtatcctt cacgggcgat gtattcttct atattttcgg agtcgatgaa
    18421 tccgcagttg cgcaaggcga tgcggagttg tttccggtag aagtccatgt gtttggagtc
    18481 actgacagtt tgttcggtct tcgggtctat gtagagcagc cgttcgattc ttcgtcctcc
    18541 gatgatgtgt tcgctgatga tttcctccgc atcttcggga gtgacttggg tatagaacgt
    18601 attgtcagga atgatcttta cgatggggcc cttttcgcag aatccgaagc agcctactgt
    18661 gatgacgtct actttgtcgg ttatcccgtt tctttcaatg gctttttgaa gattttcagt
    18721 gatgccctga ctggaagagg ctttacaacc ggtacctccg caaataagaa tctggaggtg
    18781 tgctgttccg gacgccagtc cgcaacattt ttcggaaacc ttttcattac tttcttcgcg
    18841 caatgaaaga tggtgctccg ctctcttcct gattatttgc aaatcatgga tagatagtat
    18901 tttcataagt atcagaattg ttagatttct gcaaatataa ttctttgttc ggaattaacg
    18961 ctttgtttag agaaaataaa tattcttctt tggtgccggc ttgcagaagt atggtatgaa
    19021 atctttattt ttaacacttt taatagacgg tgttaactat aatagtagca taaaaaaatt
    19081 atcttcgcat cgaaaaaggg cggataccca tatgaatcca acgatagttg gggagattcg
    19141 caagaacatt gtggagtggc ttatggggac ctgtcggtac tgtgtctgaa tggggaaatg
    19201 ctccttgtat gagttttata tagctcgatg gcaaggatgt acagcgagag gttccggcgg
    19261 ggacggggaa acgtaagttg cctccctgag acaaagggaa aaaaggggat tgtgatagcc
    19321 tgtaagtggt atgcttgcag gctatctttt tgagtatact tgaatgtccg gagtatgaag
    19381 gcagtccgta ccgctgaaaa taaaaacagc ttttctgata ccagttaggt aaattattcc
    19441 ttattttcgt attaaatacg tagcaaacgt aaataagaaa tggaagtatg agacgaattt
    19501 tgttaggatt atgtgtgctt tttttcctga atgcgcacgg gcaggagatt ccgttgccgg
    19561 agaagatgcc gcaggatcat ccgagagtac tgactacccc ggaaggaaaa aaagaaacat
    19621 ggaagttgat caagaaggaa gcatgggcac aagatgtctt taacaagctg aaagaacgga
    19681 cggaagtata tacacgacgt acggaaagtc agccggactg gttattatcc cgtttggcca
    19741 tgtactggaa gtcgcatgca acggaagtgt acgtgaaagg tgaggtgttc gaccatgccg
    19801 gaggcgagaa ggcgcctgcc ccgacggttc gctataccgg aacacgaggg acggccgcta
    19861 cgcacggtcg acctaagctg gaagatgtag taccttatga cgatagtgcg gaaggaaacg
    19921 tgactttctg caacaatgcc ctggaaggcc gtccgctgga gagtgtgcat ccgtccaaga
    19981 ccggacgcaa tattgaaagt ctgaactgtg agattctggg aattgcccgt gacgccgctt
    20041 tcctctattg gatgacggga gaggaaaagt atgcccgact ggctgccggt gttttcgata
    20101 cttatatgac gggaatctat tacagaaatg ttcctgttga cctgaatcac gggcatcagc
    20161 agacactggt ggggctgact tcttttgaag tgatccatga ggatgctttg catatcgttg
    20221 tccctttgta tgacttcctc tatcattatc tgcaatctaa ctatccggat aagatgatga
    20281 tttatgccag tgcattgaag aaatgggcgg ataatatcat cgccaacgga gtcccccata
    20341 acaactggga tttattgcag gcacgatata tcatgaacgt gggactggtg ctggaagata
    20401 ataaagagta tgcggacggg aaaggacgcg aatactatat tgactacgtt atgaaccgtt
    20461 cgagcatccg ccagtggagt ctgaccaagc tggccgatta cggctttgac tccgaaacgg
    20521 gtatatgggc ggaatgtccg ggatacagca gtgtagtcat caatgactac gcgaacttcg
    20581 cccatcagtt tgaccacaat ctgcaatatg acttggtaaa ggcaatgcct gtgctggcaa
    20641 aagcagtagc gactactccg cagtatcttt ttccgaaccg gatgatctgt ggtttcggag
    20701 atacgcatcc aagttactta agtacgaact tctttatccg gatgatacag aatgcgcagg
    20761 caaacggaaa gaaagagcag gaacgttact tcaccgcttt gctgaaatgt ctgaatccgg
    20821 aggaaggcag cgaaaaaagt ggcaagaaga atgtacgggc ctctgtcaac tccttctttg
    20881 aggacaagcc gttagtgttg gacccgaagg tggaggcggg gaaaatcgag gattatgtat
    20941 ctcctctgtt ctatgctccc aacgtatcgt ggctggtaca gcgcaacggg atgcatccgc
    21001 gcaacagtct gatgatttct ctcaacgcaa gtgaaggcaa tcatatgcac gcgaatggca
    21061 tttcgatgga gctttacgga aaaggatatg tgctgggacc ggatgcgggt atcggacttt
    21121 tcttgtatag cggtctggac tatgcggaat attactctca attccccagc cataatacgg
    21181 tttgtgtaga tggcatttcc agttatccgg tgatgaaaag taatcattct ttcgatttgc
    21241 tttcctgttt tccggcttcg gcggaaccgg gtaaaggatt tacttccgtc acctatagtc
    21301 aggtagcttt ccgtgagccg gagagcaggg cggatcagac tcgactgatg ggcattgtta
    21361 ctaccggtcc ggagacaggg tattatgtgg atgtattccg cagccggaaa gaacggggag
    21421 gcgataaaat gcacgattat ttctaccata atctaggtca gacaatgaca ctaacggctg
    21481 ccgacggcac ggatttgaat ttgcagccta ctgaagagct agctttcgca ggtgcccatc
    21541 tttatgctta ttcctactta tatgataaga aagtggctgc caccgatcag gatgtgaaag
    21601 tgacttttac catcgacatg aaggataaag gcggagatga catttccatg aatctctgga
    21661 tgaaaggaga accggaacgg gaagtgttca ccgcactggc accgatgacc gaaggattga
    21721 gccggactcc ccatatgcct tataatataa aggagcagcc tacgctcacc ttcgttgccc
    21781 ggcagcatgg agaagcatgg aaccgtcctt ttgttgctgt ttatgaacca agtacgcaga
    21841 aagagccttc ggctattcaa tctgtctctt acttcgatgc ggaagagccc ggtttgaaag
    21901 actttgccgg tatctgtgtg gaaagtaaaa acgggcgtac tgaccatatt ttctctttga
    21961 cggattcgtc gcagaccgca acctatcagg gaatgaaagt gaaagcggac tatgccgtaa
    22021 tcagtaacga atatgcggga aaccggacgc tgtttatagg gaacggaacg caactgattg
    22081 catccggtat cagtatccag acttcggagg ctgctaatgt gctgctcgaa aagaagcagg
    22141 gaaaatggta tattctttct tctgccccct gtaagatggt gattgacgga aaagcggtgc
    22201 aatccggaat aaccaccgaa ttgacgttgt tggctgtaca ataagaatca ttgttagatg
    22261 aataaacata tcattgtttt aattgaacga ttgttgtttt gcgagttttc ataaatatct
    22321 ttgatagaga ataggtgaat cgtctttatt gttcgtaata ctataaaaga attttattcg
    22381 gtaatatcat gaagaaatat tggttcttat tattagctgc attattaggt ggtgcaactt
    22441 gtatctttgc taaagacacg cttgcaacct ggaaggctcc cgcaggagtt gctttaaata
    22501 gtgattttac ggttaaggtc cgtttgcaag atggagtctg gcatacctta tcttcttatc
    22561 tgattaaggt ggatgaggta agagatacac gacattatgt agaaaatgct tcgatggcaa
    22621 tttttgattt tacaggaaaa gtggaagtag ccgtaaccta taatttggga gaagtacaga
    22681 cggcaaaagt ccgtcctctc tcgtatgata tcccatttca gatcgatggt aatacagtaa
    22741 cttttacatt agagcatcct cgaaatttgt cagtagaagt aaatggggat atttttcata
    22801 atcttcactt atttacagga tctccggaaa gaacgattcc ggacaaagat aatccggaag
    22861 taatttactt tggtcctgga atacatacag taaaaaatgg ggaattgaga gtgccatctg
    22921 gtaagactgt gtatctggca ggaggagctg ttttaatggg gcgtgtccta atcgaaaacg
    22981 tacatgatgt aaaattgcta ggaagaggaa ttatcgatta ttctataaaa ggaggtattc
    23041 gtattgcgaa ttcccgagat gtctatgtag aaggaattgt tgctactcaa tgtgcgacag
    23101 gagggtcgga aaatgttact atccgtaatg tcaaaagtat tagttattat gggtggggag
    23161 atggcatgaa tgtttttgcg agcaataacg tattatttga tggtgtcttc tgccgtaact
    23221 cagatgattg tacaactgtt tatggcactc gtttgggatt tgaaggaggt tgtcggaata
    23281 taacaatgca gaattccact ctttgggcag atgtagccca tcctattttt attggaattc
    23341 atggtaattc taaagctccc gaagttttgg aagatctgaa ttatattaat attgatatat
    23401 tggatcatag agagaaacaa gtcgattatc aaggatgtat ggctattaat gcaggtgata
    23461 acaatttaat acgcaatgtt cattttgagg acatccgtgt tgagaatttc cgtcaggggc
    23521 aacttgtcaa tttacgtatc ttttataatg aaaaatactg tactgctccc ggaagaggaa
    23581 ttgagaacgt attgtttaag aatatatcct ataccggaga gaatgcggaa ctttctatta
    23641 ttgaaggata tgatgaaaaa cgtaaggtaa agaacatacg ttttgaaaat ttgaaaataa
    23701 atggaaaatt gattgatgat aatatgccgg acaaacctcg gtggtataag acttcagata
    23761 tggcacgcat atatgtagga cctcatgtgg aaaatattgt ttttacaagt gatgtagctc
    23821 agtcacaacg tcgttttgtt catccgggta ttacttatac gcaaggtgac ctcgatcgta
    23881 tgaaagcaat ggtagaagcc agacaagaac cttattattc tacctttttg aaattgaagg
    23941 agtcttctta ttcatcactt gatgcacctg tggtgaatcg tggagagcaa ataaaggaag
    24001 ggcgatttaa tgctacaatc ggggtggatg ggcgtcgtgc tcatgattta gctcttcttt
    24061 ggcacttgac aggagaagaa gcctatgcac gtaaggctgt agaatatttg aatgcaaatt
    24121 cttattatac taatactagt agtcgtggta caggaccgtt ggataatggg aaaatttatt
    24181 tgttgattga tgcggctgaa atgatgagag attattctgg atggacacgg caagatcagc
    24241 aacgtttcaa agatatgctg gtttatccgg ggtatagtaa tacggaaaat tattctgcta
    24301 aatatgctaa ttatctggat gatacaaaaa atggagtaac tttttattgg aatatctata
    24361 attttgatgc agcgcgtttc ggtaatcaag gattgtttgc agcacgcagt atgatggcaa
    24421 tggctatcta tcttgataat gagataatgt atgaccgtgc ttatcgctat ttactgggaa
    24481 tgaaacatcg taaagatgat ttgccatatc cttcaggacc ggctatttcc agcgatcaac
    24541 ccattcatgt ttctcctact atgattgatt ataaattgtt acaacggaag aatgatattc
    24601 aggattatgg ttatgacgaa cagcttcaat attatattta tcctaatggt cagtgtcagg
    24661 aatccagtcg tgatc
//
