LOCUS       c00059_gnlPro..        16034 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|FKGMBDDL_422.
ACCESSION   c00059_gnlPro..
VERSION     c00059_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 16:48:36
            Original ID  :: gnl|Prokka|FKGMBDDL_422
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16034
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16034
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2936:6034]"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2937..6034
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="5000"
                     /detection_rule="(Fer4_7 and TPP_enzyme_C and POR and POR_N
                     and PFOR_II and not (EKR or Fer4_16))"
                     /neighbourhood="10000"
                     /product="porA"
                     /protocluster_number="1"
     cand_cluster    1..16034
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Fer4_7 and TPP_enzyme_C and POR and
                     POR_N and PFOR_II and not (EKR or Fer4_16))"
                     /kind="single"
                     /product="porA"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16034
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="porA"
                     /region_number="1"
                     /rules="(Fer4_7 and TPP_enzyme_C and POR and POR_N and
                     PFOR_II and not (EKR or Fer4_16))"
                     /tool="gutsmash"
     CDS             3..98
                     /locus_tag="ctg59_1"
                     /transl_table=11
                     /translation="YFNNFKDRLANFYWTVVIILLKLIIHLHSLS"
     CDS             607..2832
                     /locus_tag="ctg59_2"
                     /transl_table=11
                     /translation="LLGARIAPDGQWRFPPADSLPGKFVTCLLTYEDKRFFRHPGVDPV
                     AIVRAMRINLSRGKVVSGGSTITMQLARIARGNRDRTLYEKMVETGYALLLETAFDKHQ
                     ILNLYASHAPFGGNVVGIETAAWRYFGRSAADLSWAESATLAVLPNSPALIHPGRNRAR
                     LKAKRDKLLTALKEKGILDETEYGLSLLEPLPEAPVPLPDEAPHLLERLAADAPGTRIT
                     TSVNRMLQRQTQEIVNRYARDYASNHIHNLAALIADAETGEVLAYAGNVTFKADARKGN
                     QVDIITSPRSTGSILKPFLYAAMLHDGQLLPGTLVSDVPLNLNGFSPQNYNKTFYGAVP
                     AHWAIERSLNVPLVRMLSAYNTGRFMSLLKKAGMTTLRFSEEHYGASLILGGAEGTLWD
                     LTGMYASLARTLAHYRTYNGRYDPADIHPLTPYPAPPADPVRSVADKRLTDKPFLSAAS
                     IWFAFEAMSALNRPEEEADWQQFGSMKQVAWKTGTSYGGRDAWAIGTTPRYTVGVWVGN
                     ASGEGRPGLTGVGNAAPVLFDLFSLLPGSGWFDMPYDELLPMAICRLSGHKASAICDRV
                     DTLYMPRSADKTEVCPYHRLVHLSADGRFRVNSSCESVGRMIARPWFVLPPSEEYYYRN
                     YHIDYAPLPPVKPGCGEDRGRQIELIYPEHNAILYLPKGFSGKREQFVFKAAHARPDAI
                     LYWHLDDTYAGETTDHHQISFSASPGKHRLTLIDDQGNRKTISFEVK"
     CDS             2937..3170
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_3"
                     /sec_met_domain="Fer4_7 (E-value: 2e-14, bitscore: 45.0,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 1.3e-07, bitscore: 22.3,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.5e-08, bitscore: 25.5,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 3.5e-06, bitscore: 18.5,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKGAVVVNTERCKGCNLCVVACPSDVLELHPREVNNKGYHYV
                     YMKNPDDCIGCASCGLVCPDGCLTIYKKRIDN"
     CDS             3268..4350
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR_N"
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     PFOR_II"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_4"
                     /sec_met_domain="PFOR_II (E-value: 1.6e-28, bitscore: 90.1,
                     seeds: 27, tool: rule-based-clusters)"
                     /sec_met_domain="POR_N (E-value: 1.2e-49, bitscore: 160.1,
                     seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEEVKLMKGNEAIAHAAIRYGVDGYFGYPITPQSEILETLMAEM
                     PWETTGMVVLQAESEVAAINMVYGGAGTGKRVMTSSSSPGVSLKQEGISYIAGAELPCL
                     IVNVMRGGPGLGTIQPSQADYFQTVKGGGHGDYRLITLAPSSVQEMADFVGLGFELAFK
                     YSNPAIILADGIIGQMMEKVVLPPFHTRRTEEEIIAECPWATQGKTAGRKPNVITSLEL
                     DPAKMEENNIRFQAKYRKIEENEVRYEEFQCEDAEYLLIAFGSSARICQKVVEIARAEG
                     IKLGLLRPITLWPFPTKAIAAYAEKVKGMLSVELNAGQMVEDVRLAVNGKVKVEHFGRL
                     GGIVFTPDEVLNALKKNFEL"
     CDS             4393..4566
                     /locus_tag="ctg59_5"
                     /transl_table=11
                     /translation="MIRGSKIDTILTWLFMVLAVAAVVCYFAFPENRLPFLYCGGAAIC
                     FRLVQYLMRFIN"
     CDS             4762..5454
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_6"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.2e-24, bitscore:
                     77.9, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHYCPGCSHGVIHKLIAEVIAEMGMEDKTIGISPVGCAVFAYNYL
                     DIDWIEAAHGRAPAIATAVKRLNPGKMVFTYQGDGDLAAIGTAETIHAANRGENIVIVF
                     VNNAIYGMTGGQMAPTTLEGMPTATCPYGRNIALNGYPLKIGDLLAQLEGTCLVTRQSV
                     QTAAAVRKAKKMLRKAFENSMAGKGTSIVEFVSTCSSGWKMTPEKANKWMEENMFPFYP
                     LGDLKNKE"
     CDS             5480..6034
                     /gene_functions="biosynthetic (rule-based-clusters) porA:
                     POR"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg59_7"
                     /sec_met_domain="POR (E-value: 1.4e-36, bitscore: 117.2,
                     seeds: 86, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQEIIIAGFGGQGVLSMGKILAYSGLMEGKEVSWMPSYGPEQRG
                     GTANVTVILSDDRISSPVLNEYDIAIILNQPSMEKFENKVKKGGIIIYDGYGIHTPVKR
                     TDVSVYRVDAMDAATEMKNEKAFNMLILGGLLKIVPMVKLENVLLGLKKSLPERHHKLI
                     PMNEAAIKKGMEIITNVQTCH"
     CDS             6140..8251
                     /locus_tag="ctg59_8"
                     /transl_table=11
                     /translation="MKHSLYILLLLIISASALHAQRRPGGDRKGFSLGNLSKANQEVPD
                     SLLIPDSAAISNRRITAYRLTPLLGDPYIAPLDTHKLNFANSTLVESESLAVGYLANTG
                     SPAQTRIFSERKEPRDFLFADAYDYYITDPQNAQYYNTKIPYTNVMYTTMGGSESKNER
                     LKGTLTMNFGPKINVGGDLDYIYSRGYYKNNGNKLLSYRLFGSYKSDRYEAHAYLSNFN
                     FINYENGGLANDSVITNPDQYFAGERNQDDPKAFNTRYPVKAWNRVRGKQYFLSHHYNL
                     GFERELEGEVDTLGNPVKVFIPVSSIIHTLEYQDNRRRFRSEAGENLNECYLTPDGYPR
                     VFGLENGTGVDDRTSYWNLRNTFGLSLREGFQDWAKFGITAFATFDKRKFQLPAQIPGL
                     SYDPEYGSGLNASPSTIEFPITQVYDEFSTYIGAEISKRRGNILTYNARGELCVVGDDI
                     GEFRATGNLQTKFKLLKKDATISAEGYIKNVTPSFYMRHFHSRYFWWDNRDMNMIQQIY
                     AGVKINLESTRTQLSAGVESIQNYVFFNKQGMPEQKSGNLQVINARIKQDVMYRAFGWE
                     NEVAYQLSSDKSVLPLPQISLYTNMYLKFKVAKVLMVQLGANMYYNTSYYAPYYEPATQ
                     QFQVQDEVKVGNFPLVNAYVNFHLKQARFFVMGYNLGSKFVNPNYFSLAHYPLDPFVLK
                     MGVAVTFNN"
     CDS             8256..9083
                     /locus_tag="ctg59_9"
                     /transl_table=11
                     /translation="MKSRKLIGVYTGLLIIAVATMIMLWRLKTMPKAEVFPRDYPEIKE
                     EGILRLVTEYNQSGYYVAGDTIEGFQYELSQAIAQLSGLEIQIFLEMSLAESFDMLEEN
                     NCDAVARNIPITSEIKEKYLFTEPIVLDKQVLIQRTEAANNGLKPIRNQLDLAGKTLYI
                     PKDSPAQLRLQNLGHEIGDTIYVIEDELYSGEQLAIMVAKGDIDYAVCDQQTAVLSQKQ
                     LPEIDIKTDISFTQLQSWAVRKDSPILLDSLNSWLEQIRKNGTFDKIYKKYYK"
     CDS             complement(9093..10724)
                     /locus_tag="ctg59_10"
                     /transl_table=11
                     /translation="LIFVIFSGEDCDKNKYLYTQISVLKHFVYMGGIYGGKDIRPISQK
                     QDSLHGLINTILDKLPLGVFVKDAEDGFRYLYWNRFMEEITGIGTEEVEGHNDFELSFD
                     AIMPAEERLGLDRDVMETGRTIEFSGKISDAYGIPKDIEVTKFPIALSNGKPLLLALWR
                     DVTVRNKMENTLRRSQVLTKMALHSNDIRLCSIFVNPDSKRNYDDSVVQVNNWLPGKED
                     ELVDISWPRFAARVHPDDRERHDEAFRKLCSGEISEMKIELRVKYPGMDHYHWRESSAT
                     VYERDERGRVLVILGCTINIQERKGQELNLEEAKHKAELADKMKSKYLADMSHEIRTPL
                     NAITGFSELMAFADSDEERREYYEIIKTNNLLLMQLINDILDLSKIEADAIRISYEPVD
                     INGLMDTIFASIKLRMPEGVQLFLEKGSCTCCFGADSIRLLQLINNLANNAIKNTKQGS
                     ITLGYTCLPDKCLKFYVKDTGTGIAKDKLESLFTRFVKVNDYVEGIGLGLAICQGLVTK
                     MGGSMHVESELGVGSTFSFVLPSHEG"
     CDS             10880..12109
                     /locus_tag="ctg59_11"
                     /transl_table=11
                     /translation="MNFLETTPVQELTIPVILEGKDIIACAQTGTGKTAAYVLPVINEL
                     SKGLHPANAINAIIMAPTRELAQQIDQQIEGFTYFVPVSAVAVYGGTDGIAWEQQKRGM
                     EMGADIVIATPGRLLSHIKLGTVDLSQVSFFVLDEADRMLDMGFYDDIMQVYKLLPATC
                     QTIMFSATMPPKIRTLAQTILKNPEEVKIAISRPPETIMQTAYVCYDMQKLRILEDLFS
                     KSRPQRVIIFSSSKMKVKELASTLKRMKFNVAAMHSDLEQSQREEVMKEFKNGRIDILV
                     ATDVVSRGIDINDIKLVINFDIPHDPEDYVHRIGRTARGTNGEGLAITFISTEEQFQFK
                     RIEEFLDKEIYKIPVDPKFGETPLYEPEKYSNMRRGRGRPRKDGGKGKSDNRSGSGNNQ
                     RRRGRPRKEA"
     CDS             complement(12276..13949)
                     /locus_tag="ctg59_12"
                     /transl_table=11
                     /translation="VAAAVVPVQKNEEAAVSKSPVSANAPVSETLVQVADATADVPAET
                     VKPAAKKVVKKTDKPVEKPLLPPVVVESDNGELPAEIAPEVTEEPAVVETPAASTPSDE
                     PKRVVFRHPDTKSVLDQLFPFSSTPAKPEPKAREEQPAAAQQQNNPRQNNNRQNNQNNH
                     NNQRNNNNNNAVQEKQYEFDGILTGVGVLEMMPDGYGFLRSSDYNYLTSPDDIYVSQSQ
                     IKLFGLKTGDVVEGAIRPPKEGEKYFPLVKVDKINGRTPEEVRDRVPFDHLTPLFPDEK
                     FMLTARKSSKVYDNIAVRVVDLFSPIGKGQRGLIVAQPKTGKTMLLKDIANAIAANHPE
                     VYMIILLIDERPEEVTDMARSVDAEVIASTFDEPAERHVKIAEIVLNKAKRMVECGHDV
                     VILLDSITRLARAYNTVQPASGKVLSGGVDANALQKPKRFFGAARNIENGGSLTILATA
                     LTETGSKMDDVIFEEFKGTGNMELQLDRKLANKRVYPAVDITASSTRRDDLLQDENTVN
                     RMWILRKYLADMNSMEAMEFVKKRMEQTFDNMEFLASMNG"
     CDS             complement(14508..15608)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ATP_bind_3"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg59_13"
                     /sec_met_domain="ATP_bind_3 (E-value: 3.6e-34, bitscore:
                     109.1, seeds: 28, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDFDTRKYAADRHLSIEMAAREVRYGWFEEQRAATGAQAVAVAH
                     HRDDSVETLLMNLVRGTGIRGMSGIRPRNGFVVRPLLAVSREDILEWLAGRGLTYVTDS
                     TNLSDAYTRNFIRLRVLPLLEEINPSVKDAIARTSEHLSAAEAVYLHVVEEARNAVVEQ
                     GDRLSIAALMRYPSPDAILYELLKTYGFTRPVAEDVYLSLTKESGKTFFSSTHRLIKDR
                     DYLLLSPLVKEEVREYTLTGGEKVWSGPVELSFEKIVIKEDFHIRKDKNIAYFDYDKLA
                     FPLTLRTWKEGDWFIPFGMKGRKKLSDYFSDHKFSRLDKERTWLLCSGGAVIWIVGERS
                     DNRFCLDKTTKSVLVVNFFPTKSESN"
ORIGIN
        1 tgtatttcaa taatttcaaa gaccgattag ccaactttta ttggacagta gtgataatac
       61 tattaaaatt aattatacat ttgcactcgc tgtcataagc agcataaaaa tacggactat
      121 ccggcaaaca aaagttccca cataagggaa ccggacaacc ggaaacttcc tgctatttaa
      181 ctaattataa ctcatatcat gacaaaagac ttcaaaaatc ccggcctaat cagccaagtt
      241 gccgaattca tcgacaagaa aaggatcgaa gagggcatca gcatcgacac cctctgccaa
      301 tcggcccaca tcagcaaacg tatctacata gactttaaaa ggggctgaag ccggcaacga
      361 cgctccactg gttcttccgc ctcgcaaata ccttcagcca gcacactgac gaagaaaaat
      421 tcaaggaaat atggttggaa atcgcgaaaa taatgactaa cttagaggag taaaaccaaa
      481 tggcgaatga ttgtcttcca cctgtttttc ataaagctgc tgataggaac ggtcctgcat
      541 ctgaccgccc cccggacact ctttccggag gcctgctcca ccctgctcta ttcttccgac
      601 gggcagttgt taggggcacg gatcgcaccg gacgggcaat ggcgtttccc tccggcagac
      661 agtcttcccg gcaagttcgt gacctgcctg ctgacctacg aagacaaacg tttcttccgg
      721 catccgggag tagacccggt tgccatcgtc cgagccatgc ggatcaacct cagccggggc
      781 aaggtcgtca gcggggggag cacgatcacc atgcagctgg cacggatcgc gcggggcaac
      841 cgcgaccgta ccctgtatga aaaaatggtc gaaaccggct atgcccttct cctggaaaca
      901 gccttcgaca aacatcagat cctgaacctc tatgcctcgc acgccccgtt cggagggaat
      961 gtggtaggca tcgagacggc ggcctggcgc tatttcgggc gaagcgccgc cgacctctcg
     1021 tgggccgaaa gcgccacact cgccgtcctg cccaactcgc ccgccctgat ccatcccgga
     1081 cgtaaccggg cacggctgaa agccaaacgc gacaagctcc tgaccgcctt aaaggaaaaa
     1141 gggatactgg acgaaaccga atacgggctg tcgctcctcg aaccgcttcc cgaagcgccc
     1201 gtgcctctgc ccgacgaagc ccctcacctg ctcgaacggt tggcggccga cgctccggga
     1261 acgcgtatca cgacctccgt caaccggatg ttgcaacgcc agacacagga gatcgtcaac
     1321 cgctacgccc gcgactacgc ctccaaccac atccataacc tggccgccct catcgccgat
     1381 gccgaaacgg gcgaggtgct ggcctatgcg ggaaacgtca ctttcaaggc cgacgcccgc
     1441 aaagggaacc aggtagacat catcacttcg ccacgcagca cgggcagcat cctgaagccc
     1501 tttctttatg ccgccatgct gcacgacggg cagctgctcc ccggtacgct cgtttcagac
     1561 gtccccctga acctgaacgg cttctcgccg caaaactaca acaagacgtt ctacggggcg
     1621 gtcccggcac actgggcgat cgaacgttcg ctcaacgtcc cgctggtacg gatgctttcg
     1681 gcctacaaca cggggcggtt catgtcgctg ctgaaaaagg cggggatgac cacgctgcgc
     1741 ttttccgaag aacattacgg ggcttcgctg atcctgggag gcgccgaagg gacgttatgg
     1801 gacctcaccg gcatgtatgc ttcactggcg cgtacgctcg cacattaccg gacttacaac
     1861 gggcggtatg acccggcgga tattcatccg ctcactcctt acccggctcc tccggccgac
     1921 ccggtccgct cggtcgccga caaaaggctt acggacaagc cgttcctctc cgccgcctcc
     1981 atctggttcg ccttcgaagc gatgtcggca ctgaaccgcc ctgaagaaga ggcggactgg
     2041 cagcagttcg gctccatgaa gcaggtggcc tggaaaacgg ggacgagcta tggcggacgg
     2101 gacgcctggg cgatcgggac aaccccgcgc tatacggtcg gcgtatgggt gggcaacgct
     2161 tcgggagaag gccggccggg actgacaggc gtgggcaatg ccgctcccgt cctcttcgac
     2221 ctgttctcgc tccttccggg aagcggctgg ttcgacatgc cttacgacga actcctcccg
     2281 atggccatct gccgtctcag cgggcacaag gcatccgcta tctgtgaccg ggtagacacg
     2341 ctctacatgc cgcgctcggc cgacaagacg gaagtctgcc cctaccaccg gcttgtccat
     2401 ctttctgcgg acggccgttt ccgggtgaac agctcgtgcg aatcggtcgg ccggatgatc
     2461 gcacgcccgt ggttcgtact gcctccttcc gaagaatatt attaccggaa ctatcatatc
     2521 gactacgctc ccctgcctcc tgtcaaaccg ggatgcggcg aagacagggg ccggcagatc
     2581 gaactgatct atccggagca taacgccatc ctttatcttc cgaaaggctt ctccggcaaa
     2641 cgggagcagt ttgtcttcaa agctgcccac gcccgtccgg atgccatcct ctactggcat
     2701 ctcgacgaca cgtatgccgg cgaaacgaca gaccaccacc agatcagctt ctccgcttcc
     2761 cccggcaaac atcgcctgac gctgatcgac gaccagggca atcgaaagac aatatcgttc
     2821 gaggtgaaat aatcaaaaca gtttctaaaa aaggctcttt ctgtaaagtt tttactacct
     2881 ttggcagtcg caagtgagat agttagtgtt acattagttt ttaaatataa taaattatgg
     2941 cgaagataaa aggagctgtt gttgtaaaca cagagcgatg caaaggatgt aacctctgcg
     3001 tagtagcctg cccgtcggat gttctcgaat tgcacccgcg tgaagtaaac aacaagggat
     3061 accattatgt gtacatgaaa aaccccgatg actgcatcgg ttgtgcaagc tgcgggttgg
     3121 tttgtccgga cggttgtttg accatctaca agaagagaat tgacaattga caatgcacaa
     3181 ttgacaattt aacaaacaga aaaaggaatc agaatattaa tcacaaaaca aaattgtcaa
     3241 ttgtcaattg acaattaaat ataaggtatg gcagaagaag taaaattaat gaagggtaac
     3301 gaagccatcg cccatgcggc tatccgctac ggtgtggacg gttacttcgg ctacccgatc
     3361 actccgcagt cggagatact cgaaaccctg atggccgaaa tgccgtggga aacaaccgga
     3421 atggtcgtgt tacaggctga aagtgaagtg gcagccatca atatggtata tggaggtgca
     3481 ggtacgggca aacgtgtgat gacctcctcg tccagccccg gtgtcagtct gaaacaagaa
     3541 ggtatatctt atatcgcagg agccgaactg ccctgtctga tcgtaaacgt gatgcgtggc
     3601 ggtcccggcc tggggacaat ccagcccagc caggcagact atttccagac cgtcaaaggc
     3661 ggcggacatg gcgactaccg cctgatcacg ctcgctccct cttccgtaca ggaaatggcg
     3721 gactttgtcg gactgggttt cgaactcgct ttcaaataca gtaatccggc cattattctg
     3781 gcagacggca tcatcgggca gatgatggaa aaagtggtat tgcctccttt ccatacacgc
     3841 cgtacagagg aagaaatcat agccgaatgc ccgtgggcca cacagggaaa gacagccggc
     3901 cgtaaaccga atgtcattac ttcactggag ctggacccgg caaagatgga ggagaacaac
     3961 atccgcttcc aagctaaata tcggaagatc gaagaaaatg aagtccgcta cgaagagttc
     4021 cagtgcgaag atgccgaata tctgctgatc gctttcggtt cttctgcccg tatctgccag
     4081 aaggtggtgg aaatagcacg tgcggaaggc atcaagctcg gcttgctccg tcccatcact
     4141 ttgtggccgt tcccgacaaa agcgatcgcc gcttatgccg agaaagtaaa gggcatgctt
     4201 tccgtcgaac tgaacgccgg acagatggtc gaagacgtac gtctggccgt aaacggcaaa
     4261 gtaaaggttg aacatttcgg ccgtctcgga ggtatcgtgt tcacgccgga tgaagtgctg
     4321 aatgcgctga aaaagaattt tgaattatga ttgatttgta atacataatt cataaatcat
     4381 aaattaacaa cgatgattcg cggaagtaaa attgatacga tattgacctg gttattcatg
     4441 gttttggcag tggcagcagt cgtttgctac ttcgccttcc ctgaaaaccg gctgccattc
     4501 ctgtattgcg gtggcgcggc gatctgtttc cgcttggttc aatatctgat gagatttata
     4561 aattaataat gtggcaatgt gccaatcaga caatgtgcca atccatattg ttgttgacgc
     4621 attccttaac tggcacatag gcaaattacc acattattaa tataagcaca ttgaaaaatt
     4681 attcatagta tggaaattaa cgaaataata aaaccggaaa acctggtata tggaaaaccc
     4741 aggttgatga atgaaaatcc catgcactac tgtcccggtt gcagccacgg cgtgatacac
     4801 aagctgatag ccgaagtgat cgccgaaatg gggatggaag ataaaacgat cggcatctct
     4861 cccgtcggat gcgccgtttt tgcctataac tatctggata tcgactggat cgaagcggcc
     4921 cacggacgtg cgcctgccat cgcgacagcc gtcaagcgac tgaatccggg caagatggtg
     4981 ttcacgtacc agggcgacgg cgacttggct gccatcggta ccgccgaaac aatccatgct
     5041 gccaaccgtg gagaaaatat cgtgatcgta tttgtcaaca atgccatcta tggtatgaca
     5101 ggcggtcaga tggctcctac cacactggaa ggaatgccga ctgcaacctg tccgtatggc
     5161 cgtaatatcg ccctaaacgg ttatcctttg aagatcggcg acctgcttgc acaactggaa
     5221 gggacctgcc tggtcacccg ccagagcgta cagaccgcgg cagccgtccg caaggctaaa
     5281 aagatgcttc gcaaggcatt cgaaaactcg atggccggca aaggcacttc gattgtcgaa
     5341 ttcgtttcca cctgctcgtc cggttggaaa atgacacctg agaaagctaa caaatggatg
     5401 gaagagaata tgttcccgtt ctatccgtta ggagatctca agaataagga ataataagta
     5461 attattaatt tttgaagcaa tgaagcaaga aattataata gcaggtttcg gtggacaagg
     5521 ggttttgtca atgggtaaga tcctggctta ttccggcctg atggaaggaa aggaagtcag
     5581 ttggatgcct tcttacggcc cagaacaacg aggcggtaca gccaacgtaa ccgtcatcct
     5641 gagcgacgac cgcattagct ctcccgtatt gaacgaatat gacattgcca tcatcctgaa
     5701 ccaaccttcg atggagaagt tcgaaaacaa ggtgaaaaaa ggcggtatca ttatttatga
     5761 cggatacgga atccatacac cggtgaaacg gaccgatgtc agtgtatatc gtgtggatgc
     5821 gatggacgcg gctaccgaga tgaaaaacga gaaagcattc aatatgctga tcctcggcgg
     5881 actgctgaaa atcgttccga tggtgaaact ggaaaacgtt ttgttaggct tgaagaaatc
     5941 cctgcccgaa cgccaccaca agctcatccc gatgaacgag gcggctatca agaaaggcat
     6001 ggagattata accaatgtgc aaacgtgcca ttaaggcgct tagctaaatg tgccaatatg
     6061 ccaataaaaa tataactaat attaattggc atattggcac attgttcata ttggtacatt
     6121 atcactatct ttgcccctca tgaagcatag cctatacata ttattactct tgataatatc
     6181 cgcttcggcc ctgcatgcac aacgccgacc aggtggagac cggaaaggat tctcactcgg
     6241 aaacctatcc aaagccaatc aggaagtccc tgacagcctg ctgattccag acagcgcagc
     6301 aataagcaac agacgtatca cggcctatcg gctaacccct ctgttgggcg atccttatat
     6361 tgccccgttg gacacgcata aattgaattt cgccaacagc acgctggtag aatccgaatc
     6421 gctggcagtc ggctacctgg ccaatacagg gtcaccggca caaacccgca tcttttccga
     6481 acgtaaggaa ccacgggatt tcctgtttgc cgacgcttac gattattata tcacggaccc
     6541 tcagaacgca cagtactaca acacgaaaat cccttataca aacgtgatgt acacgactat
     6601 ggggggaagt gaaagcaaaa acgaacggct gaaaggcacg ctgaccatga acttcggtcc
     6661 gaagatcaac gtaggtggcg acctggacta tatctacagc cgcggatatt acaagaataa
     6721 cggtaataag ctgttaagct accgcctttt cggcagttac aagtcggatc gctacgaagc
     6781 gcacgcttac ttgagcaact tcaacttcat caattacgaa aacggaggct tggccaacga
     6841 ctcggtcatc actaacccgg accaatattt tgccggcgag agaaaccagg acgaccccaa
     6901 ggcattcaat acacgctatc cggtcaaggc atggaaccgg gtacgtggca aacagtattt
     6961 cctcagccac cattataacc tcggattcga gcgcgaactg gaaggggaag tggatacgct
     7021 gggaaatccc gtgaaagtat ttattcccgt atccagtatc attcatacac tggaatatca
     7081 ggacaaccgc cgccgtttcc gatcggaagc gggcgagaac ctgaatgaat gttatctgac
     7141 cccggatgga tacccgcgtg tattcggttt ggaaaacggc acgggtgtcg acgaccgcac
     7201 ttcctactgg aatctgcgca atacgttcgg tctttccctc cgcgaaggtt ttcaagactg
     7261 ggccaagttc ggcatcactg cctttgccac tttcgacaag cgcaaattcc agttgccggc
     7321 ccagataccg ggattgtctt acgaccccga atatggaagc gggttaaacg cctctccttc
     7381 caccatcgaa tttccgatta cacaagtgta tgatgaattc tcgacatata tcggagccga
     7441 aatctccaaa cgccggggaa acattctgac ttacaatgcc cgtggagaac tttgtgtcgt
     7501 aggcgacgat atcggggaat ttcgggccac gggaaacctg caaaccaaat tcaagctatt
     7561 aaaaaaagat gcgacgatca gtgcggaagg atacatcaag aatgtcactc cttccttcta
     7621 tatgcgtcac ttccattccc gctatttctg gtgggataac cgggatatga acatgatcca
     7681 gcaaatctat gccggagtca agatcaacct ggagtccaca cggacacagt tgtctgccgg
     7741 ggtcgaaagc atacagaact atgtattctt caacaaacaa ggaatgccgg aacagaaaag
     7801 cgggaatctg caagtgataa acgcccgcat caaacaagat gtcatgtacc gcgctttcgg
     7861 atgggaaaac gaagtggcct accagctgag cagcgacaaa agcgtactgc ctttgcctca
     7921 aatcagcctg tataccaata tgtatctgaa attcaaggta gcaaaggtgc tgatggtgca
     7981 attgggagcc aatatgtatt ataacacttc ttactacgcc ccgtattacg aaccggccac
     8041 acagcagttc caggtacagg acgaagtgaa agtcggcaat ttcccgcttg tcaatgccta
     8101 cgtcaacttc cacctgaaac aggctcgttt ctttgtgatg ggttataacc tgggttccaa
     8161 gttcgtcaat ccgaactatt tctcgctggc gcactatccg ctggatccgt tcgtcctgaa
     8221 aatgggcgtg gctgtcacat tcaacaactg atcttatgaa atcgaggaaa ctgataggag
     8281 tctacaccgg gctgctgata atcgccgtag caaccatgat catgttatgg cgcctgaaaa
     8341 ccatgccgaa ggctgaagtc ttcccacgcg attatccgga gatcaaagaa gaaggaatcc
     8401 tgcggctggt gaccgaatac aatcaatcgg ggtattatgt ggcaggtgac acgatagaag
     8461 gtttccaata tgaactgagc caggctatcg cccaattatc aggtctggaa atacagatat
     8521 ttttggagat gagcctggcc gaaagcttcg atatgcttga agagaacaat tgcgatgccg
     8581 ttgcccgcaa tatcccgatc accagcgaga tcaaagagaa atatctgttc accgaaccga
     8641 tcgtcctcga caaacaagtc ctgatacaac ggacggaagc ggccaataac gggctcaagc
     8701 ccatccgcaa ccaactcgat ctggccggta agaccctata tatccccaaa gattctcccg
     8761 cccagctcag gctacaaaac ttaggacatg agatcggcga tacgatctac gtgatagaag
     8821 acgaattata ctccggggaa cagcttgcca tcatggttgc caaaggagat atcgattatg
     8881 ccgtttgcga ccagcagacg gctgtccttt cccaaaagca actcccggaa atagatatca
     8941 aaacagacat aagtttcacg caactccaat cctgggcagt ccgcaaagat tcccctatcc
     9001 tgctcgacag cctgaacagc tggctggaac agatacgcaa gaacggtaca ttcgacaaga
     9061 tatacaagaa atattataaa taatgcatca ctttatccct catgcgacgg cagcacgaag
     9121 gagaaagtcg aaccgacccc taattcggat tccacgtgca tggaaccacc cattttcgta
     9181 accagccctt ggcagatggc aagccccaaa ccgatacctt ccacataatc gttcacctta
     9241 acgaagcgtg tgaaaaggct ctccagttta tcttttgcaa tgccggttcc cgtatccttc
     9301 acataaaatt tcagacattt atccggcagg caggtatatc ccagcgtgat acttccctgc
     9361 ttggtattct taatcgcatt attcgccaga ttattgatca attgcaacag acggatacta
     9421 tcggctccga aacagcacgt gcagctacct ttttccaaga acaactgcac tccttcgggc
     9481 atacgaagtt tgatagaggc gaatatcgta tccatcagcc cgtttatatc gaccggttca
     9541 taactgatcc tgatagcgtc ggcttcgatc ttggacaggt cgagtatatc gtttatcagt
     9601 tgcatcagca gcaggttatt ggtcttgatg atctcataat attccctacg ctcctcatcc
     9661 gaatcggcaa aagccatcaa ttcggaaaaa ccggtgatcg cattcagcgg ggtgcggatc
     9721 tcatggctca tatccgccag atacttggac ttcatcttat cggcaagctc cgccttgtgc
     9781 ttggcttctt ccaggttcag ctcctgccct ttgcgttcct gtatgttgat cgtacatccc
     9841 aggatcacaa gcacccttcc ccgttcatcc cgttcgtaga cggttgccga cgattcacgc
     9901 cagtggtaat gatccattcc cgggtatttc acacgcaact cgattttcat ttccgatatc
     9961 tctcccgaac ataatttccg aaaagcctca tcgtgtctct ccctgtcgtc aggatgaacc
    10021 cgcgcggcaa aacgaggcca tgaaatatcg accagctcgt cttctttacc cggcaaccag
    10081 ttatttacct ggacaaccga atcatcataa ttccgtttgc tgtcaggatt cacgaatatg
    10141 gaacagaggc ggatatcatt ggaatgcagg gccatcttag taagtacctg cgaacgtctc
    10201 aaggtattct ccatcttgtt gcggaccgtg acgtcacgcc acaaagccag caaaaggggt
    10261 ttgccattac tcaaggcaat cgggaatttc gtgacttcga tatccttcgg gatgccatac
    10321 gcatcagaaa tcttcccgct aaattcaata gtcctacccg tctccatgac atcacgatcc
    10381 agccctaaac gctcttctgc gggcatgatc gcatcaaaac tcagttcgaa atcattgtga
    10441 ccctcaactt cttccgtacc gataccggtt atttcttcca tgaaacggtt ccaatacaga
    10501 tacctgaaac catcttctgc atcttttaca aaaacgccta acggtagttt atccaaaatc
    10561 gtattgatca atccatgtaa tgaatcttgc ttttgtgaga ttggccggat gtccttccca
    10621 ccataaatgc cgcccatata aacaaaatgc tttaaaacgc taatttgggt ataaagatat
    10681 ttatttttat cacaatcttc cccggaaaat atcacaaaaa tcaatcttcc cttgaaaaaa
    10741 taactctttt gaaagaagag ctgcgttcta tataacaaat attgccaaat attatctacc
    10801 tttaccggga atttaatgat gaaagatgag atttgacgaa ttggacttag aagaggccgt
    10861 attggacggc cttgacgcaa tgaattttct ggagacaact ccagtacagg aactgacgat
    10921 tccggtcatt ttagaaggga aagacattat tgcctgtgca cagacaggga caggaaagac
    10981 tgcggcttat gtgttgccgg tgatcaatga actcagcaaa ggattacatc cggccaatgc
    11041 catcaatgcc atcatcatgg ctcccacacg cgaattggcc caacagatcg accagcagat
    11101 cgaaggtttc acctattttg tcccggtttc cgccgttgcc gtctacggag gcacggacgg
    11161 tattgcctgg gaacagcaaa agcgagggat ggaaatgggg gccgatatcg tgatcgctac
    11221 ccccggacgt ctgttgtcgc atatcaaact gggcactgtc gatctgtcgc aagtatcctt
    11281 cttcgtcctg gatgaagcgg accggatgct cgatatggga ttttatgacg atatcatgca
    11341 ggtctacaaa ctactgccgg caacctgcca gaccatcatg ttctctgcca caatgcctcc
    11401 caagatccgg acactggccc aaacgatcct gaaaaacccg gaagaagtca agatagccat
    11461 ctcccgtcca cccgaaacaa tcatgcaaac ggcctatgtc tgctatgaca tgcagaaact
    11521 acgcatattg gaagacttgt tctcaaagag ccgtccgcag cgtgtcatca ttttttcgtc
    11581 ctcgaaaatg aaagtaaaag agctggcatc cactctcaaa cggatgaagt tcaacgtcgc
    11641 agccatgcat tctgaccttg agcagtcaca gcgtgaagag gtgatgaaag agttcaagaa
    11701 cggacgtata gacatcctcg tcgccactga cgtcgtctcg cgcggtatcg atatcaacga
    11761 catcaagctg gttatcaatt tcgacattcc ccacgacccg gaagactacg tgcaccgcat
    11821 cggccgtacc gcccgcggaa caaacggcga agggctggcc atcactttca tttcaaccga
    11881 agaacaattc caattcaaac gcatcgaaga attcctggat aaggaaatct ataaaatacc
    11941 ggtcgatccc aaattcggcg aaacaccttt atacgagccc gaaaaatact ccaacatgcg
    12001 tcgtggcaga ggacgccccc gcaaagacgg cggaaaaggg aaaagcgaca accgctccgg
    12061 cagcggcaac aaccaacgcc gcagaggaag accgaggaag gaagcatagg ctaacgttta
    12121 taaatatgtc gaccggcatt tatacaaatg ccggtcgacg attataagtg catagcgttg
    12181 caaaatatag aaaacagaga ttcgaatcca atataaaaaa cgcagaccag gccgagcccg
    12241 atctgcgttt ttatcaatat cgagaatccc ctaacttatc cgttcatcga agccaagaac
    12301 tccatattat cgaatgtctg ttccatgcgc ttcttgacaa attccatagc ctccatagag
    12361 ttcatatcgg ccaggtactt acgcaggatc cacatacggt tcacggtgtt ttcatcctgc
    12421 aacaggtcgt cgcggcgcgt gctggacgct gtgatatcga cagccggata aacacgtttg
    12481 tttgccagct tgcgatccaa ctgcaactcc atattacccg tacctttgaa ttcttcaaag
    12541 atcacatcgt ccatcttcga accggtttca gtcaatgccg ttgccaggat cgtcaggctg
    12601 ccgccgtttt cgatgttacg ggcagccccg aagaaacgtt tcggtttctg caatgcgttc
    12661 gcatccacac caccggagag cactttaccg gaagccggct gaaccgtatt gtaagcacga
    12721 gccagacgtg tgatagagtc taacaggatc acgacatcat gtccacattc caccatacgt
    12781 ttagccttat tcaatacgat ttcggcaatt ttcacatggc gttcagccgg ttcgtcgaaa
    12841 gtagaagcaa tcacttcggc atctacgcta cgggccatat cggtcacctc ttcaggacgt
    12901 tcgtcgatca gcaggataat catatacact tcaggatggt tggctgcgat cgcattggcg
    12961 atatccttca acagcatcgt cttaccggtc ttcggctgtg ccacgatcag accacgctgt
    13021 cccttgccga tcggcgagaa cagatctact acacgtacgg cgatattatc atatactttc
    13081 gaagacttgc gggccgtcaa catgaatttt tcgtccggga aaagcggagt cagatgatcg
    13141 aaaggaacac ggtcacggac ttcttcaggc gtacggccgt tgatcttgtc cactttgaca
    13201 agcgggaaat atttttcacc ttccttcgga ggacggatag ccccctccac cacgtcgccg
    13261 gtcttcaggc cgaacagctt gatctgcgac tgcgatacgt aaatatcatc cggggaagtc
    13321 aggtagttat aatcggaaga acgcaagaaa ccatatccgt caggcatcat ttccagcaca
    13381 ccgacacctg tcagtatacc gtcaaactca tactgttttt cctgcacagc attgttatta
    13441 ttgttgttgc gctggttgtt atgattattc tggttgttct gtctgttgtt attctggcga
    13501 ggattgttct gctgctgggc ggctgcaggt tgttcttcac gcgctttcgg ttccggtttt
    13561 gcaggtgtgg aagagaatgg gaaaagttga tcgagaactg atttggtgtc cggatggcgg
    13621 aataccacac gtttaggttc gtctgacgga gtcgaagcgg caggagtttc cacgacagcc
    13681 ggttcttccg ttacttcagg agcgatttcg gccggaagct ctccgttatc cgattccacg
    13741 acaacaggag gaagcaacgg tttctctaca ggcttgtcag tcttcttaac cactttcttt
    13801 gctgccggtt ttaccgtttc ggcagggacg tcggccgtag catcagctac ctggacaaga
    13861 gtttcggata caggagcatt ggctgaaacc ggacttttgg aaacggctgc ctcttcgttt
    13921 ttctggacag gaacaacagc cgcggccact ttttctttct tgtcaatacg agtccgtctt
    13981 ttacgttcgg gctgttccgg agcttccgga gcgacctctt ctaccgaaac ttcaacgggt
    14041 gtggcgggag cagcgacttt cgttttggca tcagcttttg cgcctttcgg agccgcagct
    14101 tttgttttct tagccttagt ctgcctttct gctttctttg cttccttttc tttctccttt
    14161 tcagcctgga tgccggcgta tgaaatggcc tgttcgtcaa gaattctgta tacaagttcc
    14221 tctttcttaa gggaacttac ttttttaata cctaactctt ccgctatact ttgcaactca
    14281 ggaaggagtt tttcatttag ttctagaatg ttatattttt gcataatgcg aagtgaataa
    14341 taaaaacgac gtacttacac gaccggacac ggcacgcgta caacgcaatc attgtatctt
    14401 ttataatttg ataattaata atttcatgtg aaaaccggat tgttgagcta atttgaatca
    14461 ttagtaacac atctgcggag taaatctttg caaatgtaat aatattttca gttactctcg
    14521 ctttttgtcg gaaaaaaatt cacaactaac acacttttag ttgttttgtc caggcaaaaa
    14581 cgattatcgg aacgttctcc tacaatccag ataacagcgc ctccgctgca taaaagccac
    14641 gtccgttcct tatctaaacg gctgaattta tgatccgaga aataatcgct taatttcttc
    14701 cgccctttca tgccaaaagg aataaaccaa tctccttctt tccatgtacg cagggtaagc
    14761 ggaaaagcca gtttgtcgta atcgaaataa gcgatatttt tatctttccg gatatggaaa
    14821 tcttccttaa taacaatctt ctcgaaagaa agttcgacag gaccggacca aactttctcg
    14881 ccaccggtca gtgtatattc acggacctct tcttttacaa ggggagataa caataaatag
    14941 tcccgatctt ttatcaaccg gtgcgtagaa gagaaaaagg ttttgcccga ttctttcgtc
    15001 agggacaaat aaacatcctc cgccaccgga cgagtaaagc cataggtttt gagtaactcg
    15061 tataaaatag catcgggcga cgggtaacgc atcaaggcgg caatcgaaag gcggtcccct
    15121 tgctcgacca cggcattcct cgcctcttcc accacatgca gataaacggc ttcggctgcc
    15181 gacagatgtt cggacgtacg ggcgatcgca tccttcacgg aaggattgat ttcctccaga
    15241 agcggaagga cacgcaggcg gataaaattg cgcgtataag catcggaaag gttggtactg
    15301 tcggtcacat acgtcaaacc gcgtccggca agccactcca agatatcctc acggctcacg
    15361 gcaagcaaag ggcgcaccac gaaaccgttc ctcggacgaa tcccgctcat tcccctgatg
    15421 ccggtcccac gtaccagatt catcaaaagc gtttccacac tgtcgtcacg atgatgagcc
    15481 acagcgacag cctgcgcccc ggttgcagcc cgttgctctt cgaaccagcc atagcgcacc
    15541 tcgcgggcag ccatttcaat ggagagatgc cggtcggctg catattttcg ggtatcgaag
    15601 tccgtcatca ggaaagggac atccagtttt cgggcatact cccttacaaa ctgttcatca
    15661 cgcagggatt cgtctccccg caaatgaaaa ttacaatgcg ccgcaataca ggaatagccc
    15721 gactccacca aaatggtgag tagggctatt gaatctgctc cgccacttac accgaccaga
    15781 accggacggt tttccgtaag caaccgatat ttctctatat atgcacggac aacgtcgcgc
    15841 atccgattat tcttctatgc ctgccaattc agggtcgatc atgatacgac cacagtattc
    15901 gcaaacgatc actttcttac gcaacttgat atccaactgt ttctggggcg gaatcttgtt
    15961 gaaacaacca ccgcaggcac cacgctgtac atatacgaca gccaagccgt tacgtgcccc
    16021 cttgcggata cgtt
//
