LOCUS       c00023_gnlPro..        23249 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|POBLKHNG_113.
ACCESSION   c00023_gnlPro..
VERSION     c00023_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 15:46:41
            Original ID  :: gnl|Prokka|POBLKHNG_113
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 45704
            Orig. end    :: 68953
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..23249
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[55704:58953]"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13249
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /neighbourhood="10000"
                     /product="Putrescine2spermidine"
                     /protocluster_number="1"
     cand_cluster    1..23249
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /kind="single"
                     /product="Putrescine2spermidine"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..23249
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="Putrescine2spermidine"
                     /region_number="1"
                     /rules="(minimum(2, [AdoMet_dc, Spermine_synt_N,
                     Spermine_synth]) or (Orn_DAP_Arg_deC and Sacchrp_dh_C))"
                     /tool="gutsmash"
     CDS             1477..2934
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FGGY_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_46"
                     /sec_met_domain="FGGY_C (E-value: 4.1e-38, bitscore: 123.0,
                     seeds: 64, tool: rule-based-clusters)"
                     /sec_met_domain="FGGY_N (E-value: 2.6e-80, bitscore: 261.4,
                     seeds: 11, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYYIGIDLGTSAVKLLLMEESGKICNIVSREYPLFFPHPGWSEQK
                     PEDWFAQSMEGMKELTKDIDRAQVAGIGFGGQMHGLVTLDKDDNVIRPAILWNDGRTGE
                     ETEYLNTVIGKDKLSQYTANIAFAGFTAPKILWMQKNEPENFKKVVKIMLPKDYLAYRL
                     SGSFCTDVSDASGMLLLDVKNRCWSKEMLEICGITEEQLPKLYESWEVVGTLKPEIAKE
                     LGFSENVKVVAGAGDNAAAAVGTGTVGDGQCNISLGTSGTVFISSKNFGVDENNALHSF
                     CHADGSYHLMGCMLSAASCNKWWAEEILQTKDFAAEQAPIQKLGENHVFFLPYLMGERS
                     PHNNPDARGVFFGMSMDSTRADMTQAVLEGVAFGLRDSLEVARNLGIKIERTKICGGGA
                     KSPLWKKIIANVMNLKVDVLENEEGPSMGGAMLAAVGCGAYPDVETIGKKFAKVVDTVE
                     PDPELVAKYEERYQKFRTLYPAMKPLF"
     CDS             complement(3046..3981)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     58; E-value: 2.3e-18)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg23_47"
                     /sec_met_domain="LysR_substrate (E-value: 3e-33, bitscore:
                     106.9, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.2e-18, bitscore: 58.0,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFQGMEYIYEVYKEKSFSKAAAALFISQPSLSANVKRVENRIGYP
                     IFDRSTKPLQLTEVGKHYIQAVEKVMDIENNLENYLLDLGNLKTGTLNVGGSNFFSSWI
                     LPPLIADFSQKFPHVQISLVEESTAKLSQFLQAGKLDLVIDNCILDNQIFEHYIYQKEQ
                     LLLAVPKNYSVNTRLQEYQIPIEEIRNGQFRSSHIPSVPLNKFENEPFIILRSDNDTGK
                     RALTICQENHFSPSVVFRLDQQMTAYNIACLGMGITFIGDLLLSRVPTNSELVFYKLPG
                     QSSKRTVFFYWKKGRYISRAMEEFLKLPFS"
     CDS             4097..5521
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Lyase_1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FumaraseC_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_48"
                     /sec_met_domain="Lyase_1 (E-value: 1.4e-94, bitscore:
                     308.9, seeds: 17, tool: rule-based-clusters)"
                     /sec_met_domain="FumaraseC_C (E-value: 4.9e-22, bitscore:
                     70.2, seeds: 737, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKTDYRVERDSIGVKDIPEDVYYGVQSLRAAENFHITGLNMHPE
                     IINSLAYIKKAAAITNCEVGLLEKKKAQAIVQACDEIVSGKFHNEFIVDPVQGGAGTSL
                     NMNANEVIANRAIEILGGKKGDYTIINPNDDVNCGQSTNDVIPTAGKMTSLRLLQNLKK
                     QLLRLYDALNEKATEFDHIIKMGRTQMQDAVPIRLGQEFKAYSVAIMRDIHRMDKAMDE
                     MRTLNMGGTAIGTGINADEGYLRRIVPNLTEISGMDFIQAFDLIDSTQNLDPFVAVSGA
                     VKACAVTLSKMSNDLRLMSSGPRTGFGEINLPAKQNGSSIMPGKVNPVIPEVVNQVAFN
                     IIGNDVTITMAAEAGQLELNAFEPIIFYCMFQSIDTLGYAVQTLVDNCIVGITANEERC
                     RYLVENSVGIITAISPHLGYQKAADIAKKAIKTGESVRSLILKEKLMDEDELNRILDPV
                     HMTEPGISGKDYLIKK"
     CDS             complement(5630..7315)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) FTHFS"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_49"
                     /sec_met_domain="FTHFS (E-value: 2.7e-275, bitscore: 905.7,
                     seeds: 408, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGFKSDIEIAQECEMLPITQIAEKAGIDDKYLEQYGKYKAKIDYN
                     LLKESDKKDGKLILVTAINPTPAGEGKTTTTVGLADGMQRLGKSVMVALREPSLGPVFG
                     VKGGAAGGGYAQVVPMEDINLHFTGDFHAIGAANNLLAAMIDNHIFQGNALNIDPRKIT
                     WRRCVDMNDRQLRNVVDGLGGKTNGMPREDGYDITVASEIMAVLCLASDIKDLKERLSK
                     IIIGYTYGKVSEQKPVTAGDLHAEGAMTALLKDALKPNLVQTLEHVPAIVHGGPFANIA
                     HGCNSVTATKMAMKLADYAITEAGFGADLGAEKFLDIKCRMAGLKPSAVVIVATVRALK
                     YNGGVAKADLNNENLEALEKGIPNLLKHVSNIKNVYKLPCVVAINAFPTDTKAELDFVE
                     AKCKELGVNVALSEVWAKGGEGGIKLAEEVIRLVEEPNDFSYAYELEGSIEDKLNQIVQ
                     KVYGGKKVVLTANAQKQAKQLEALGFGNCPICVAKTQYSLTDDQTKLGAPTDFEVTVRN
                     LKISAGAGFIVALTGEIMTMPGLPKVPAAERIDVDETGKITGLF"
     CDS             8541..9998
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) OKR_DC_1_7_arginine"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_50"
                     /sec_met_domain="OKR_DC_1_C (E-value: 1.5e-13, bitscore:
                     43.2, seeds: 113, tool: rule-based-clusters)"
                     /sec_met_domain="OKR_DC_1_7_arginine (E-value: 3.4e-126,
                     bitscore: 413.0, seeds: 39, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYERQQHAPIYEALERFRKKRVVPFDVPGHKRGRGNPELAQLLG
                     EKCVGLDVNSMKPLDNLCHPVSVIREAEELAADAFGAAHAFLMVGGTTSAVQSMILSVC
                     KAGDKIILPRNVHKSAINALVLCGAIPVYVNPEVNAQLGISLGMEVSQVEKAMDENPDA
                     VAVLVNNPTYYGICSDLRTIVKKAHARGMKVLADEAHGTHLYFGRNLPVSGMAAGADMA
                     AVSMHKSGGSLTQSSLLLLNKSMNAEKVRQIINLTQTTSASYLLLSSLDISRRNLALRG
                     EESFEKVAGMAQYAREEINEIGGYYAYGMDLINGTSVFDFDVTKLSIYTLGNGLAGIEV
                     YDLLRDEYDIQIEFGDICNILAYISIGDRLQDIERLVGALADIERLYKKDSTGMLSGEY
                     IAPAVVASPQQAFYAEKESLPMEQAAGRISGEFVMCYPPGIPILAPGEMVTQEIVEYIL
                     YARDKGCSMQGMEDPKVEHLQVLKGGI"
     CDS             10001..10861
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synth"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Spermine_synt_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_51"
                     /sec_met_domain="Spermine_synth (E-value: 1.9e-53,
                     bitscore: 172.6, seeds: 15, tool: rule-based-clusters)"
                     /sec_met_domain="Spermine_synt_N (E-value: 2.8e-15,
                     bitscore: 48.0, seeds: 13, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELWYSEFHTGNVKLSVRINRQLFSGESEFQRIDVFESEEFGRFV
                     ALDGEIVFSDKDEFIYDEMVTHVPMTVHPNVKNVLIIGGGDGGVARELIHYPQIESIDV
                     VESDKMFVDVCAEMFPDIAQGLKDERVNIYYEDGLRFLRNKKARYDLIINDSTDPLGHT
                     EGLFTKEFYGSCYKALRDDGIMVYQHGSPFYDEDEVECRKMHRKVFRSFPVSRVYQAHI
                     PTCPSGYWLFGFASKKYHPLEDFRPERFDNLNIETWYYTTNLHRGAFMLPKYVEDLLEE
                     EENSL"
     CDS             10858..12138
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Sacchrp_dh_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Sacchrp_dh_NADP"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_52"
                     /sec_met_domain="Sacchrp_dh_C (E-value: 1.8e-43, bitscore:
                     141.5, seeds: 375, tool: rule-based-clusters)"
                     /sec_met_domain="Sacchrp_dh_NADP (E-value: 1.1e-35,
                     bitscore: 114.7, seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRLLVIGCGGVASVAIRKCCQNSDVFTEIMIASRTKEKCDALKE
                     KIESTTKTKIETAKVDADNAAEVAELIRAYKPDAVLNVALPYQDLTIMDACLEAGADYI
                     DTANYEAEDTEDPTWRAIYEKRCKEKGFTAYFDYSWQWAYDEKFKEAGLTALLGTGFDP
                     GVTSVFSAYALKHYFDEIHTIDILDCNGGDHGYPFATNFNPEINLREVSANGSYWEDGH
                     WVETEPMEFKSVYDFPEVGKKDMYLLHHEEIESLAKNIPGVQRLRFFMTFGQSYLTHMK
                     CLENVGMLSTAPVEFNGQEIVPIQFLKALLPDPASLGPRTVGKTNIGCIFTGVKDGKEK
                     SIYIYNVCDHQECYKEVESQAISYTTGVPAMIGSMMVVTGQWKKPGVFNVEEFDPDPYM
                     EALNKWGLPWKVCEDPELVKVWKANED"
     CDS             12128..13249
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Putrescine2spermidine: Orn_DAP_Arg_deC"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg23_53"
                     /sec_met_domain="Orn_DAP_Arg_deC (E-value: 1.2e-14,
                     bitscore: 46.4, seeds: 500, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIDQLQTPCYVIDEKKMRENLEILKKVQEDTGCKILLAQKAFSG
                     FALYPMIGKYLAGTTASGLFEARLGYEEMGKENHVFSPAYRTEDIEELDRICDHIIFNS
                     TAQLKKFKEVCTGASLGLRINPECSTQGDHAIYDPCAPGSRLGVTRENFDVECLKWIDG
                     LHFHTLCEQNADDLEKTLQAVEEKFGEFLSEVSWLNMGGGHHITREDYDVKLLEKCIQH
                     MKETYDLDIYLEPGEAVALNAGYLVTEVMDIVENEIRTLILDASAACHMPDVLEMPYRP
                     PLKDSGEAGEKAYTYRLSSCTCLAGDVIGDYSFDREIRIGDKLYFMDMAIYSMVKNNTF
                     NGMPLPDIAVMHEDGECEVIRHFGYEDFKSRLS"
     CDS             13284..14387
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PAD_porph"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_54"
                     /sec_met_domain="PAD_porph (E-value: 3.4e-128, bitscore:
                     419.3, seeds: 436, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEVTEKNRTKYRMPGEFEPHEGCVMIWPERPGSWNYGAREAQKAF
                     VKVAEAIGESEKVYMLVSKAQMENAKNQLGNVSGVTLLECETDDAWARDVGATMVLDEK
                     GAVCGVDWQFNAWGGTFDGLYRNWEKDDRVAAFICRTLGCPCLDARPFVLEGGSIHSDG
                     EGTLIVTEACLLSQGRNPQMSREQIEEQLKYWLGVHKIIWLPCGIYQDETNEHVDNVCA
                     FVRPGEVVLAWTEDETDPQYAMSLADLKVLEQETDAKGRKFKIHKLPIPQKPVCLTRED
                     VDGFVFEEGEDEREAGERMAASYVNFYISNGGIILPQFGDENDKRAVEILQKCFPERRI
                     YPIDARAIIVGGGNIHCITQQIPGKNI"
     CDS             14489..15367
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CN_hydrolase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_55"
                     /sec_met_domain="CN_hydrolase (E-value: 4.5e-56, bitscore:
                     182.0, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRNVTVAAVQMKCSKSVEKNIAHAEELVRQAAAKGAEIVLLPELF
                     ERPYFCQERRYEYYEYAQTAEENPAVRHFSRVAAELGIVIPVSFYEKEVNNTYNSVAVL
                     DADGKNLGIYRKTHIPDDHYYQEKFYFTPGDTGFKVFDTRFGTIGVGICWDQWFPETAR
                     CMALQGAELLFYPTAIGSEPILECDSMEHWRRCMQGHAASNLIPVIAANRIGEETVEPC
                     PENGMQKSALDFYGSSFITDNTGALCAELPGGEEGVLVSTFDLDALKADRLNWGLFRDR
                     RPEMYAKIVGK"
     CDS             15595..16056
                     /locus_tag="ctg23_56"
                     /transl_table=11
                     /translation="MNRKEFLEILRSQLAGQMQEGKAAAHIRYYEDYIQSQVRGGRSEQ
                     EVLQELGDPHLIAKTLIDTDDGNTQEDYGEYSSYGSSYGNETELPHQQEKRWKKVIDLS
                     TWHGRAVVIAAAAVIIVLLILIIGVAIPFFIILAIILYFLSWLKKRNDQ"
     CDS             16260..20957
                     /locus_tag="ctg23_57"
                     /transl_table=11
                     /translation="MKHNFKLKERLGALLLAMLFVLQAILGLVPVCVTQAAPLTVETWD
                     SDKVVDYGYRFNMKFQPGITTYESFGCDNLDREAFSDNGKSERDTECVRVGADYKAGSA
                     GMRYNNVGKDGNGNIVDVRLILVGVENAEPRYDLRTAESIVQNKGGATFAWKDNEAYPM
                     VGFSKNSIGVFIYSVGYAKVKFQFLKHGTEETLPISGHGTIRDIDAGQGVRIPSDSSLD
                     NAYVLKNNDYLTVDGNSVSSPLGSVEPDDPRGWLNLFYNTDNFTVEFCHQFRLDKWDKS
                     REDAIAKAGSQERWAEITRNKYLDPSGNSYCPNFKGQKYCKAYAYFDFTSYCFGDVEMK
                     KAPEKRVGEANCTWEQAAATSKEKPFGIRQGQEFQYMIRAEVTPNRLKSFVVQDILEDC
                     LTIEDASKVSIVNDAGQTVTDWFDVAVEGQKVTCRAKAESLQDEAFTDNQTYTFTLKVR
                     QRPESEINISKYLAEDGYSILVPNHASMSYERTNGSGDTMDTETVWVKGVIPPELEVKK
                     NTSQYEWKTGDIIDYEVLVSQTKQDVKAVNVVITDELPSCLQFLEGQYAVETSQGGENC
                     TLTGQGENGWKAECPSLKYGETITIRFKCQASADSNGQEWENIVTATADNLINPETGEQ
                     ESRKDMAEVWPNSPQLEIDKTADKYEWQAGEQVAYRIVVNNVTAGTIAKDVTITDIGLP
                     QGLVLAGGAQSMEVLGVQQQVNYPVPDKKTGQAYEARSVDSQLNADENGFSFYCSYVPY
                     SQPVTIIFHCIAQEEANGHESVNAATVKAANTDERSDDAEVYVNSGEFWIEKSADHYEW
                     QVGEQVQYNVVVENKKAGTVARNVTVWDTGMPAGLALSSAEDVSVSGIPQNITQLTAGT
                     KDVLNQLNPEFYNETSEKPVNYEFLQEGSGWRLNISDLPANTPVMISFLCTVAEAANGM
                     ESINVANVQAQNAPVSQDDAEVYVNTAVLSIEKSFQNPYLAAGDGRAENEFRVGEQVNY
                     QVTVNNLQKGSIARNLVISDLSLPEGLALDGAEDAVTVSGVPAVIQNPVAGTDDAGNQL
                     NPENYKETVEKPVSCQVTRQGTGWIVTISDLPYQTPVTVNFRCTAQESVNGMEIVNTAQ
                     AYADNAQKVKDSSKIWVNSPVLNVEKTTDKPFYKYGDIITYRIVLTQEQTGCVARNVTL
                     QDVIDTQGVRLLKDSVILMDEKGNVADADVQINDDNTFLMSTGRTLVRDSRYSICDNDK
                     GGLFEQVMYNPLDCQEQKSMIVEYQAAVIDAALAGQKVHNTAVADSSEKIPATGETETE
                     VHSPILEIVKESDKKEYASGEKGYYKLTVRQLREDVTDQNIVIEDKLETQGASIVKDSI
                     FVKKNGIELKDAKIEADDTGFVIQTGASLSDMDKIEVCYEVVFKTESTEPEKIVNTAKA
                     RGDISPEIAAQQEVYVKTKAEPTATPTPSATPKPTETPKPTETPKPTEVPKPTEQPKAT
                     PTPSVPGTCPKMTPVPTKAPLASYNGGNNGGTTSGNGGSSYGNSGGYGSYQGGSMAGSS
                     KTGDVRPFKMMAVLGLIGMGLLTGGVVIYRRTVSGKRNIKGMPRK"
     CDS             20954..21841
                     /locus_tag="ctg23_58"
                     /transl_table=11
                     /translation="MKKLRTFAVSMIIAAIGLLIYCAGFYIKSYEQNLAARQEYAELSK
                     MAGVKNRAGAGLLADGKKTDEDSSTKNSEKKRRKKQRRSSESKNKNCTDEIRESFGISW
                     ENLRKINSQTVAWITVPGADISYPVVQAADDEYYLKHNFRGEEDLFGCIFLEHDIKKNF
                     TDSHSILYGHNIEGNMMFANLNRYEQPEFLKKCPEIEITTPKRKFLYKIFSVEQASSQS
                     PAFEYGYKLSSPAYRRQLSILKNNSMYDTGVEPDERERMVTLITCNSRLDKEIRMAVHG
                     ICHECYGIEKAEPK"
     CDS             22033..23124
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peripla_BP_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:Periplasmic binding protein-like domain (Score:
                     107.3; E-value: 3.4e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg23_59"
                     /sec_met_domain="Peripla_BP_3 (E-value: 3.3e-33, bitscore:
                     107.3, seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDNGKPKYFSLMEQLRSDIMSGAIRPGEKLPSENELSQKYSLSR
                     HTVRKALGILEQDGYVEAFHGRGTYCSENMRHIKNSKNIAVVTTYISDYIFPRLIQGMD
                     NVLSESGYSIILKNTANSRQKEARCLEELLKKDIDGLIIEPSKSEMICKHRNLYQNLDK
                     FEIPYVFIQGIYSEMRDKPHILMDDAQGGYLVTKYLLELGHKKIKGFFKADDMQGLERH
                     KGYVKALQESGIAYDPDDVVWFHTEDRKVKPALMAKEMVQSGQLPDGIVCYNDQIAVQV
                     MEELEKMGVRIPDDISITGYDNSLYAQRGSGITTIAHPQEKLGEMAAELILEKINGVPE
                     EESKVERLIYPELIIRGSCRKIL"
ORIGIN
        1 gatatggaga aagctcttga agatgtaaac aaagcagagt gtaatgcgct ggttgttttc
       61 cttggaaact tcggacctga aactcctgaa actctgatcg cagagagatt tgacggacct
      121 tgcatgtatg tagcagcagc agaaggtgac ggcgatatga tcaacggcag aggtgatgct
      181 tactgtggta tgcttaactg ctcctacaac ttaaaaatgc gtcatctgaa agcatatatt
      241 ccggaatatc ctgttggaac agcagatgat attgcaaaga tgatcgctga tttcgtaccg
      301 gttgcacgtg cagtcatcgg tgtcagcaat cttaagatca ttacttttgg accgcgtcca
      361 caggacttct tcgcatgcaa cgcacctatt aaaggcctct atgagctggg cgttgagatt
      421 gaagagaact cagagcttga tcttcttgtt tctttcaaag agcatgaaaa tgaccctcgt
      481 atcccggaag tttgtgcaga tatggccaaa gagatgggcg aaggcaaata ttatgctgac
      541 cttaatgtga aaatggcaca gtttgagctt acacttcttg actgggcaga ggctcataag
      601 ggagcaagaa aatacgttgc atttgctgac aaatgctggc cagcattccc gtcacagttt
      661 ggatttgaac cttgctatgt aaacagccgt ctggcttcca gaggaatccc ggtatcctgt
      721 gaggttgata tctacggagc actcagcgag tacatcggac tttgcatttc caatgatgca
      781 gttacactgc ttgatatcaa caactctgtt ccacagtata tctatgatga agatattaaa
      841 ggaaaatacg attataagct tactgataca tttatgggat tccattgtgg aaatactcct
      901 gcatgcaaga tgtgtgattc cagagctgtt aaatatcagc tgatccagca cagacttctt
      961 gagccggcag gatctgaacc agacttcaca agaggaactc ttgaaggtga tatcgctgca
     1021 tctgacatta cattctatcg tttacagtgc aattccgagg gcgagctggt ttcttatgtt
     1081 gcagaaggtg aagtactgga tgtacctaca agatcattcg gtggtatcgg tattttcgca
     1141 atcaaagaaa tgggaagatt ctaccgtcac gtactgatcg agggcaacta tccgcatcat
     1201 ggagcagtta tgtttggaca ttacggaaaa gcattctatg aggtagtgaa attccttgga
     1261 ctggatgtta agaagattgg atataaccag ccggcaggtg taagataccc gacagaaaat
     1321 ccatggggtt aatgagaaat cagtaaaacg gattattaat gttcatgtga agtgaatgaa
     1381 tctgaataca gaataaataa actgacacta tattaaaggc atcccggggc tttgctctgg
     1441 gatgtattag attagaaata gaaaaggaga gcacttatgt attatattgg tattgacctt
     1501 ggtacttccg ctgtaaaact tcttcttatg gaagaatcag gaaaaatctg taacatcgta
     1561 tccagagaat atcctttatt cttcccacat ccgggctggt ctgagcagaa accggaagac
     1621 tggtttgcac agagtatgga aggtatgaaa gagctgacaa aggatatcga cagagcgcag
     1681 gtagcaggaa ttggttttgg cggccagatg catggtctgg taacacttga caaggatgat
     1741 aatgtgatcc gtcctgcaat cctctggaat gacggacgta caggcgaaga gacagaatat
     1801 ctgaatacag tgatcggaaa agacaaactt tcacagtata cagcaaatat tgctttcgca
     1861 ggcttcacag caccgaagat cctctggatg cagaaaaatg agcctgagaa ctttaagaag
     1921 gtagtaaaga ttatgcttcc taaggattat ctggcatatc gtctgtccgg ttctttttgt
     1981 acagatgttt ctgatgcttc cggtatgctt cttcttgatg tgaagaaccg ctgctggtca
     2041 aaagaaatgc tggagatctg tggaatcaca gaagagcagc ttccgaaact gtatgagagt
     2101 tgggaagtag taggaactct gaaacctgag attgcgaaag aacttggatt cagtgagaat
     2161 gtaaaagttg ttgcaggtgc aggtgacaat gcggcagctg ctgtaggaac aggtacagtt
     2221 ggtgacggtc agtgtaatat ttctcttgga acatccggaa ctgtgtttat ttccagtaaa
     2281 aactttggtg tggacgaaaa taacgcactt cattctttct gtcatgcaga tggaagctat
     2341 catctgatgg gatgcatgct cagcgcagct tcctgtaaca aatggtgggc agaggagatt
     2401 cttcagacaa aggatttcgc agcagagcag gctccaattc agaagctggg agagaatcat
     2461 gtattcttcc ttccatattt gatgggagaa cgttcacctc ataataatcc tgatgcaaga
     2521 ggtgtattct tcggaatgtc catggacagc acaagagcag acatgacaca ggctgttctg
     2581 gaaggtgttg cctttggtct tcgtgattcc ctggaagttg caagaaacct tggaatcaag
     2641 attgagagaa ccaagatctg cggtggtgga gctaagagcc cactgtggaa gaagatcatt
     2701 gcaaacgtta tgaacctgaa ggttgatgtt ctggagaacg aagaaggacc gtccatgggt
     2761 ggagctatgc tggcagcagt aggctgtggt gcttacccgg atgtagaaac catcggtaag
     2821 aaatttgcca aagttgttga tacagtagaa ccggatcctg aactggttgc aaaatatgaa
     2881 gagagatatc agaagttcag aactctgtat ccggcgatga agccattgtt ctaatcgaat
     2941 atctgcctga catactgggg ttgttgtgct tatttagcac aacaacccca ttttgacgta
     3001 catctgatga tgaccaatca ccataaccta tttgattatg acatatcagg aaaagggcag
     3061 cttcaggaat tcttccatgg ctctgctgat atagcggcct ttcttccagt aaaaaaacac
     3121 agtgcgttta ctgctctgac cgggtagctt ataaaaaaca agttctgaat ttgttggaac
     3181 tctggagagc agaagatccc cgatgaaagt gatacccatt cccaaacatg caatattata
     3241 ggcagtcatc tgctgatcca ggcgaaatac tacagaaggc gaaaagtgat tttcctgaca
     3301 aatggtaagt gcacgcttac cggtatcatt atctgaacga agaataataa atggttcgtt
     3361 ctcgaatttg tttaatggaa cagaaggaat atgagaagaa cggaactgtc cgttccggat
     3421 ttcctcaata ggaatctgat attcctgcag tcgggtattt actgaataat ttttgggaac
     3481 cgctagaaga agttgttctt tctggtagat ataatgttca aaaatctggt tatccagaat
     3541 acagttatca attaccagat ctaactttcc ggcctggaga aactgggata gctttgctgt
     3601 actttcttct acaagagaaa tttgaacatg ggggaatttt tgggaaaaat cagcaataag
     3661 gggaggcaga atccacgaag aaaaaaagtt actgccacct acattaagag ttcctgtttt
     3721 gagatttcct agatccagta ggtagttttc gagattattt tcaatatcca tgactttttc
     3781 aacagcctgt atataatgtt ttccgacttc agttaactgt aaaggtttgg tacttcgatc
     3841 aaaaatagga taaccaatgc ggttttccac acgttttaca tttgcactta aagaaggctg
     3901 cgaaatgaaa agagcagcag cagctttgga aaagcttttt tccttgtaga cctcatagat
     3961 gtattccatt ccctgaaaca tataaactcc tccgatatat aacttaaaca ctatatattt
     4021 tataaaaata tatgtatttg attatattat agcagagata tataatgagg gcaaatacat
     4081 gggagggcga ataactatga aaaaaacaga ctatcgtgta gaaagggatt ctattggtgt
     4141 aaaggatatt ccggaagatg tatattatgg agtacaatcc ttacgtgcgg ctgaaaattt
     4201 ccacattacg gggctgaata tgcatccgga aattattaac agtcttgcat acataaaaaa
     4261 agcagcagcg ataaccaatt gtgaggtggg gcttcttgag aagaaaaaag cacaggcgat
     4321 tgtccaggca tgtgatgaaa ttgtttcagg aaaattccat aatgaattta ttgtggatcc
     4381 tgttcaggga ggagctggca catctttaaa tatgaatgcc aatgaagtaa ttgcaaatcg
     4441 cgcgattgag atactgggag gaaaaaaggg cgattataca attataaatc ctaacgatga
     4501 tgtgaattgt ggacagtcta ccaatgacgt tattcctact gccggtaaaa tgacttctct
     4561 tcgtttgttg cagaatctga aaaaacagct tcttcgcctc tatgatgctc ttaatgaaaa
     4621 agctacagag tttgatcaca taataaaaat ggggcgtaca cagatgcagg atgcagtacc
     4681 aattcgtctg ggacaggaat ttaaggcata ttcggtagca atcatgcgtg atatccacag
     4741 aatggataaa gcaatggatg aaatgcggac tcttaatatg ggaggtactg ctattggaac
     4801 aggaattaat gcagatgagg gctatctgag aagaattgtt ccaaatctca ctgaaatatc
     4861 gggaatggac tttatacagg cttttgatct gattgattcc actcagaatc tggatccatt
     4921 tgtagctgtt tccggtgctg tgaaagcatg tgcggtaact ctttccaaaa tgtcaaatga
     4981 tctccgtctg atgtcctccg gtccacgtac tggttttggg gagattaatc ttccggcaaa
     5041 acagaatggt tcctctatta tgccaggtaa agttaatccg gttattcctg aagtagtgaa
     5101 tcaggttgct tttaatatta ttggtaatga tgttaccatt accatggctg cagaggctgg
     5161 tcagctggaa ttaaatgcgt ttgagccgat tattttctat tgcatgttcc agtctatcga
     5221 tactcttggc tatgcagtcc agacattggt ggataattgt attgtaggaa ttacggcaaa
     5281 tgaagaaaga tgccgttatc tggtagaaaa cagtgtaggt attatcactg caatcagccc
     5341 ccatcttgga tatcagaagg ctgcggatat tgcaaaaaag gcaattaaga caggcgaatc
     5401 tgtaagaagt ctgattctga aagaaaagct tatggacgag gatgaactta atcgcattct
     5461 ggatccggtc catatgacgg aacctggtat ttccggaaaa gattatctta taaaaaaata
     5521 aagaaaaaaa caggcgggaa aatcttcccg cctgtaaaat cgtctggaca catatcatat
     5581 ataaatatga tttttatatt tttgaattat tcgactgatt tcaaccggat tagaacagac
     5641 ctgtgatctt acctgtctcg tctacgtcga ttctctcagc agccggaact ttaggaagac
     5701 ctggcattgt catgatctcg cctgtaagag ctacgatgaa tcctgcacca gcggaaatct
     5761 tcaggttacg tactgtaact tcgaagtcag taggagcacc cagtttagtc tggtcatctg
     5821 ttaagctgta ctgtgtctta gctacacaga tcgggcagtt gccaaagcca agagcttcta
     5881 actgtttcgc ctgtttctga gcgttagctg tcagaactac tttcttaccg ccatatactt
     5941 tctgaacgat ctggttcagt ttgtcttcga tagaaccttc cagttcatat gcataggaga
     6001 agtcgtttgg ttcttcaaca agacggataa cttcttctgc aagtttgatt ccgccttcgc
     6061 cgccttttgc ccatacttca gaaagagcaa cgttaacgcc cagttcttta catttagctt
     6121 ctacaaagtc aagctctgct tttgtatctg tagggaatgc gttgatagca acaacacatg
     6181 gaagtttgta tacgtttttg atgttggaaa cgtgttttaa caggttcggg ataccttttt
     6241 caagagcttc caggttttca ttgttaaggt cagctttagc aacgccgccg ttgtatttca
     6301 gggcacgtac tgtagctacg attacaactg cgcttggttt taaaccagcc atacggcatt
     6361 tgatatcaag gaatttctca gcaccaaggt cagcaccgaa accagcttct gtgattgcat
     6421 aatcagcaag cttcatagcc atctttgtag ctgttacaga gttacatcca tgagcgatgt
     6481 ttgcgaatgg tccgccatgt acgattgcag gaacgtgttc cagagtctgt acaaggtttg
     6541 gtttcagagc atcttttaac agggctgtca tagcgccttc tgcgtgaagg tcacctgctg
     6601 ttacaggttt ctgctcggaa acttttccgt atgtatatcc gatgatgatc ttggataatc
     6661 tttctttcag gtctttgatg tcgcttgcaa gacagagaac tgccatgatt tcagatgcaa
     6721 ctgtgatgtc gtatccgtct tcacgaggca taccgtttgt ctttccgcca agaccatcta
     6781 ctacgttacg aagctgacgg tcgttcatat ctacacatct tctccatgtg atcttacgtg
     6841 ggtcgatgtt taatgcattg ccctggaaga tatggttatc gatcatagct gcaagtaagt
     6901 tgttagctgc gccaatggca tggaagtcac ctgtgaagtg aaggttaata tcttccatag
     6961 gaacaacctg tgcatatccg ccgcctgctg caccaccttt tacaccgaat accggtccta
     7021 aggatggctc acgaagagct accataacac tcttgccaag tctctgcata ccatctgcaa
     7081 gacctacagt agtagtagtt ttaccttctc ctgctggagt tgggttgata gctgtaacga
     7141 ggattaattt tccatccttc ttatcacttt ctttcagaag attgtagtcg atttttgctt
     7201 tgtattttcc gtactgctcc agatatttgt cgtcaatacc tgctttctct gcgatctgag
     7261 taattggaag catctcgcat tcctgtgcaa tttcaatgtc tgatttgaat cccataattg
     7321 tttttctcct ttcgtttccg cataacatga aaaacttctg ttgctgttca ctccgcgatc
     7381 agcaacaatt attaattgaa agaagtattg gccggtctgc ctggtattcc tgatttctgc
     7441 cctgaaagtt ataaaaaaag gccagtatct gaatatttca aatactgccc agacggtcgg
     7501 ctcccacaaa cctccgactc cacgtggttt gcactccact ctttccgtca gtactcgaag
     7561 gttctttcaa ttgatgaata caatatatca ttttgagaaa aaaatgtcaa gaaaattttt
     7621 gttgaaacgt caaaaaatgt gagtaaactg gataaaagtt gtgcaaattg ataagagaag
     7681 agaatcgtaa tccctggtaa tgaaagaaaa tacgttttct caagggaaga aattgttaaa
     7741 aaataaacac agttttccct gataaatgaa gaaaatataa aaagcgggta aagctagagc
     7801 gtgtctgaaa aatcattccc gcaatctgca cgcccccact ttgcgggata tttcacccga
     7861 attcagttgc cgtagcccgc tacggcgccc tcatccgggc aaaatatccc acaaattgtg
     7921 acgcacatct tgcagaaagc ctttttcaga cacgctctag tgcaaaatat ggaaaatgga
     7981 attgacaaca gttcagaaga tatgttattc tcatctttag tatgaaaaga cactatcgtt
     8041 ttcatgcaaa tatttgctca cattcagaga cagtttctga atgttaagcc atacggacag
     8101 gcggggcagt tgccgggtgg gagacaccac attattgatt gagttagaag ctcaaatttt
     8161 ataagttgat tactttataa taatcagtgc gtaagcacac atcatcttgt gaaacggtca
     8221 ataagagcat agcatatatt tgccagcgat tgaagacgac agcagtcatg aatatttcag
     8281 aatacgggaa caggcacagg atacagacgg atttatacgg gaaatccggt cagtatataa
     8341 agagacagag cctgagaaat tctatagatc atgagagaag cagatggtga atgaacttat
     8401 ctgcttcttt ttttgtgcag atatagcaaa tatatagaga aataattgaa tcattgtgcc
     8461 ggtttgaggc agtatacaat tgctgaatga tagaactgta tttgccggta catgacgaca
     8521 ggaaaagagg aacatgtcaa atggattatg aaagacaaca gcatgcgccc atatatgaag
     8581 cactagaacg tttccgaaag aagagagtcg ttccctttga tgtgccggga cataaaagag
     8641 gaagaggaaa tccggagctt gcacagttgc tgggagagaa atgtgtgggg ctggatgtta
     8701 attctatgaa gccgctggac aatctctgcc acccggtttc ggtgatcaga gaagcggagg
     8761 agcttgcagc agatgctttt ggcgcagcgc atgcattcct tatggtagga ggaaccacat
     8821 ctgcagtgca gagcatgatc ctgtctgtct gcaaggcagg ggataagatc attctgccgc
     8881 gaaatgtaca taaaagtgcc atcaatgccc tggtactgtg cggtgcaatt ccggtttatg
     8941 taaacccgga ggtgaatgcg cagctgggca tttcccttgg catggaagtc agtcaggtgg
     9001 agaaggctat ggatgagaat ccggatgcgg tggcagttct tgtaaataac cctacctatt
     9061 atggaatctg ttcggatctg cggactatcg taaagaaggc tcatgcaaga ggaatgaagg
     9121 tgctggcaga tgaggctcat ggaacccatc tttatttcgg cagaaacctt cctgtgtccg
     9181 gaatggcggc aggtgctgac atggcggcag tttccatgca caaatccggc ggaagtctga
     9241 cacagagttc gctgctgctt ttgaataaga gtatgaatgc agagaaagtg cgccagatca
     9301 tcaatctgac tcagaccaca agcgcttctt atcttctgtt gtccagtctg gatatctcca
     9361 gaagaaatct ggcactcagg ggagaggaat cctttgaaaa ggtcgcaggg atggcgcagt
     9421 atgccagaga ggagatcaat gagatcggcg gttattatgc atatggtatg gatctgatca
     9481 atggaaccag tgtttttgat tttgatgtta caaaactctc catttataca ctgggaaatg
     9541 ggctggcagg tattgaagtt tatgatcttc tcagagatga atatgatatt cagatcgagt
     9601 ttggagatat ctgtaatatt ctggcttaca tttccattgg agacaggctt caggatattg
     9661 agagactggt aggggcattg gctgatattg aacgtctgta taagaaggac agcacaggta
     9721 tgctttccgg ggaatatatc gcacctgcag tggtggcgtc tccacagcag gcattttatg
     9781 cggagaaaga atctctgccc atggaacagg cggcaggcag gatcagcggt gaatttgtta
     9841 tgtgttatcc tccgggaatc ccgattcttg ctcctggaga aatggtgaca caggaaattg
     9901 tagaatacat tctttatgca agagacaaag gctgttccat gcagggaatg gaggatccga
     9961 aggtagaaca tcttcaggtc ctgaaagggg gtatctgatc atggaattat ggtattccga
    10021 gttccataca ggaaatgtaa agctttctgt ccggattaac cgacagttat tttcagggga
    10081 aagtgaattt cagagaatcg atgtgtttga gtctgaagaa tttggaagat ttgtggctct
    10141 ggacggtgag atcgtattct ctgataaaga tgaatttatt tatgatgaaa tggtcacgca
    10201 tgtgccaatg acagtacatc ccaatgtaaa aaatgttctg atcatcggcg gcggtgacgg
    10261 tggagttgcc agagaactga tccattatcc acagattgag agcattgatg tggtggaatc
    10321 cgataaaatg tttgtggatg tatgtgcgga gatgtttccg gatattgccc agggactgaa
    10381 ggatgagaga gtcaacattt attatgaaga cggccttcgg ttcctgcgga ataaaaaggc
    10441 cagatatgac ctgatcatca atgattccac agatccgctg ggacatacag agggactttt
    10501 tacaaaggaa ttctacggaa gctgttataa ggctcttaga gatgacggaa tcatggttta
    10561 tcagcatgga agtccttttt atgatgagga tgaggtggaa tgcagaaaga tgcacagaaa
    10621 ggttttccgg tcatttccgg tgagcagggt ttatcaggca catatcccta cctgtccctc
    10681 gggatactgg ctttttggat ttgcatcaaa gaaatatcat ccactggaag atttcaggcc
    10741 ggagaggttt gataatctta atatagaaac atggtattat acaacaaacc ttcacagagg
    10801 agcatttatg cttccaaaat atgtagaaga tttactggaa gaggaggaaa acagtttatg
    10861 agcagattat tggtaatcgg atgtggtggg gtagcttcag tggcaattcg caaatgctgt
    10921 cagaatagcg atgtttttac agagattatg atcgcaagca ggacaaagga aaaatgcgat
    10981 gcactcaaag agaagattga aagtacaacg aagacaaaaa ttgagacagc aaaggtagat
    11041 gcggataatg cagcagaggt cgcagaattg atcagagcct ataagccgga tgctgtcctg
    11101 aatgtggcac ttccatatca ggatcttacc atcatggatg catgtctgga agccggtgcg
    11161 gattatattg atactgccaa ttatgaagca gaggatacag aagatcccac atggcgtgca
    11221 atctacgaaa agagatgtaa agaaaaaggc tttactgcat atttcgatta ttcctggcag
    11281 tgggcttatg atgagaaatt taaggaagca ggactgactg ctcttctggg aaccggtttt
    11341 gatccgggtg ttaccagtgt attcagtgct tatgccctga agcattattt tgatgaaatc
    11401 cataccattg atattctgga ctgtaacggc ggtgatcatg gatatccttt tgccacaaac
    11461 tttaacccgg agatcaatct tcgagaggtt tccgcaaatg gttcctactg ggaagacgga
    11521 cattgggtag aaacagagcc tatggaattt aaatctgtct acgattttcc tgaggtagga
    11581 aagaaggata tgtatcttct tcatcatgaa gagattgaat cactggcaaa aaatattccg
    11641 ggagtacaga ggctccgttt ctttatgaca ttcggacaga gctatctgac acatatgaaa
    11701 tgtctggaaa atgtaggaat gctttccacc gcacctgtgg aatttaatgg acaggagatc
    11761 gtgccgatcc agtttttgaa agctcttctg ccggatcctg catctctggg tccgagaaca
    11821 gtgggtaaaa caaatatcgg ctgtattttc acaggtgtta aggacggaaa agagaaaagt
    11881 atttatattt ataatgtatg tgatcatcag gaatgctata aagaggtgga atcccaggca
    11941 atctcctata caacaggtgt tccggctatg atcggttcca tgatggtagt gaccggacag
    12001 tggaagaagc cgggtgtatt taatgtggaa gaatttgatc cggatccata tatggaagca
    12061 ctgaacaaat ggggacttcc atggaaagtc tgcgaagatc ctgaactggt aaaggtctgg
    12121 aaagccaatg aagattgatc aactgcaaac tccctgctat gtgatcgatg agaagaagat
    12181 gcgggagaat ctggagattt tgaaaaaagt ccaggaggat accgggtgta agatccttct
    12241 ggcgcagaaa gcgttttcag gctttgccct gtatcccatg atcggaaaat atctggcagg
    12301 taccactgcc agcggtctgt ttgaggcaag gcttggatat gaagagatgg ggaaagagaa
    12361 tcatgttttt tcccctgctt accgtacaga agatatagag gaactggatc gtatctgtga
    12421 ccatattatc tttaattcca cagcacagct gaagaaattt aaagaagtgt gtaccggagc
    12481 cagtctggga ctccgtatta atccggaatg ctccactcag ggggatcatg cgatctatga
    12541 tccctgtgcg ccgggttcca gactgggggt taccagagag aactttgacg tggaatgtct
    12601 gaaatggatc gacggactgc attttcatac gctctgcgaa cagaatgcgg atgacctgga
    12661 gaaaacattg caggcggtag aggagaagtt tggagaattt ctgtctgagg tttcctggct
    12721 gaatatgggc ggcggacatc atattaccag agaggattat gatgtaaagc tcctggaaaa
    12781 atgtattcag catatgaagg aaacctatga tctggatatt tatctggagc ccggggaggc
    12841 tgttgccctg aatgccggat atctggtgac agaggttatg gacattgtgg aaaatgagat
    12901 cagaacgctg attttggatg cttctgcagc ctgccatatg ccggatgtgc tggagatgcc
    12961 atatcgtccg cctcttaagg acagcgggga agcaggggag aaggcatata cctaccgctt
    13021 atcttcctgc acctgcctgg caggagatgt gatcggagat tattcctttg acagagagat
    13081 ccggatcggg gacaagctgt attttatgga tatggcgatt tattctatgg tgaagaataa
    13141 tacatttaac ggtatgccgc tgccggatat tgcggttatg catgaggacg gagagtgtga
    13201 ggttatcaga catttcggat acgaagactt taagagccgg ctttcctgat atctgccggg
    13261 ttatcaaaga aaaggagaca gacatggaag ttacagagaa gaacagaaca aaatatcgta
    13321 tgcccggaga atttgagcct catgagggat gtgtgatgat ctggccggaa cgtcccggtt
    13381 cctggaatta tggggcaagg gaagcacaga aagcatttgt gaaagttgca gaggctattg
    13441 gagagagcga aaaggtgtat atgctggttt ccaaagctca gatggagaat gcaaagaatc
    13501 agcttgggaa tgtttccggt gtgactttgc tggaatgcga gacagatgac gcctgggcca
    13561 gagatgtggg agcaaccatg gttctggatg agaaaggggc ggtctgtgga gttgactggc
    13621 agtttaatgc ctggggaggt acctttgacg ggctttaccg gaactgggag aaggacgaca
    13681 gggtggctgc ctttatctgc aggactcttg gttgtccatg tctggatgcc agaccttttg
    13741 tgcttgaggg cggttccatc cattctgacg gagaggggac tctgatcgtt acagaggcct
    13801 gtcttctgag tcagggacgc aatcctcaga tgagcaggga acagatagag gaacagttga
    13861 agtactggct cggtgtccac aagattatct ggcttccatg tggaatctat caggatgaaa
    13921 ccaatgagca tgtggataac gtgtgcgctt ttgtaaggcc cggagaggtt gtgcttgcat
    13981 ggacagagga tgagacagat ccgcagtatg ccatgtcttt ggctgatctg aaggtgctgg
    14041 aacaggaaac agatgcaaaa ggcagaaaat ttaagattca taagcttccg attcctcaga
    14101 aaccggtctg ccttacccgg gaagatgtgg atggctttgt gtttgaagag ggagaagacg
    14161 aacgggaagc aggagaacgg atggctgcca gttacgtgaa tttctatatt tccaatggag
    14221 ggatcatcct tccacaattt ggggatgaaa atgacaaaag ggcagtggag attctgcaga
    14281 agtgttttcc tgaaagaagg atttatccca ttgatgccag agccatcatt gtcggcggtg
    14341 gaaatattca ctgtatcacc cagcagattc ccggaaaaaa tatctgaccc tgatgcagaa
    14401 aaactttgag agtcatgtgt ttgagggtta tacctgaaag ttatgaaaaa acttacttat
    14461 gtaaacagga gcaggaggaa cagacaggat gagaaatgta acagtggcag cagttcagat
    14521 gaaatgcagt aaaagtgtgg agaaaaatat tgcccatgca gaggaactgg tgcgtcaggc
    14581 agcagcaaag ggagctgaga ttgttcttct tccggagctt tttgaacggc cctatttctg
    14641 ccaggagcgc agatacgagt attatgaata tgcgcagact gcagaggaaa accctgcagt
    14701 gcgtcatttc agcagggtag cggcagagct ggggattgtg attccggtca gcttttatga
    14761 aaaagaggtc aataatacct ataacagcgt tgcggttctg gatgcagatg gaaagaatct
    14821 cggtatttat cggaaaacac atattccgga tgaccattat tatcaggaaa aattctattt
    14881 cacaccggga gataccggct ttaaggtttt tgataccaga tttggaacca ttggagttgg
    14941 aatctgctgg gatcagtggt tcccggaaac agcaagatgt atggcgctgc agggagcaga
    15001 gctgctcttt tatcccactg ccatcggaag tgaacccatc ctggaatgtg acagcatgga
    15061 acactggaga agatgtatgc agggacacgc tgcctccaat ctgatccctg tgatcgctgc
    15121 caacagaatc ggtgaggaaa cagtagagcc atgtccggaa aatggaatgc agaaatctgc
    15181 tcttgatttt tatggctcct cttttatcac agacaacaca ggtgctctct gtgcagaact
    15241 gcccggaggg gaagaggggg tgcttgtaag cacttttgac ctggatgcat taaaggcaga
    15301 cagactgaac tggggacttt tcagagaccg cagaccggag atgtatgcaa aaattgtcgg
    15361 gaaatgacat acaagccaaa attccattgc cgcaggcaat ctggaatgaa ttttggctca
    15421 gttactgaga acggagtgaa cagtaactga gtttataaga atttcataaa aagtttatga
    15481 ttatattagt tgctacctgc ggtatatatg gtaaaataag agtacgaacg ttactgataa
    15541 cggagcgagc agtagagttt tgacatgtat ttctggcaaa atggagtgta gaagatgaac
    15601 agaaaagaat ttttggaaat cctgagaagc cagcttgccg gtcagatgca ggagggcaaa
    15661 gcagcagcac atatcaggta ttatgaagat tatatacagt ctcaggtacg tggcggacgt
    15721 tcagagcagg aggtactgca ggaactggga gacccgcatc tgatagcaaa gactctgatc
    15781 gatacagacg atggaaatac acaggaagat tacggagagt attcttctta cggaagcagt
    15841 tatggcaatg agacagagct tcctcatcag caggagaaaa gatggaaaaa agtaatcgat
    15901 ctttctacct ggcatggcag ggctgttgtt attgcagcgg cggctgttat aattgtttta
    15961 ctgatactga taatcggagt tgcgattccg ttttttatta ttcttgcaat tattctttat
    16021 tttctttcat ggctgaagaa aagaaatgat caatgaaaat ctgtgcaggg tttcagaaaa
    16081 gaaaccctgc gcagaatctt aaaaatctta agtgtaaacg ttcttgtttc acgatattaa
    16141 ttccccttga atatttataa tcatacaatc tcaacttatt tctattcttt aatcctgcca
    16201 ggtgcaggga aaaatcccac attcattttt atattttttg ttcggaaagg agacggaaaa
    16261 tgaaacacaa tttcaaactg aaagaacgtc ttggagcttt gctgcttgca atgctttttg
    16321 ttctgcaggc aattctgggg cttgtgcctg tctgcgtaac tcaggcggca ccgttaactg
    16381 tagaaacatg ggacagtgac aaggtggtag attatggtta tcgctttaac atgaagtttc
    16441 agcccggaat taccacatat gaatcttttg ggtgtgataa tctggacagg gaagcttttt
    16501 cagacaatgg aaaaagtgaa cgtgacacag agtgcgttcg tgtaggagcg gactataaag
    16561 ccggaagcgc agggatgcgt tataacaatg taggaaaaga tggaaatgga aatattgttg
    16621 atgtcagact cattcttgtg ggagtagaga atgcagaacc ccgttatgat ctgcgcactg
    16681 cagaatcgat tgttcagaat aaaggcggag ctacgtttgc atggaaagat aatgaagctt
    16741 atccaatggt tggcttttcc aaaaacagta tcggtgtatt tatttattct gtaggatacg
    16801 caaaggttaa gtttcagttt ctgaagcatg gaacagaaga aacactgccg atcagtggcc
    16861 atggaaccat acgtgatatt gatgcgggac agggagtccg tattccgtca gacagcagtc
    16921 tggataatgc atatgttctg aaaaacaatg attatctgac ggtagatggg aattctgtaa
    16981 gctcacccct tggttccgtt gagccggatg atccgagagg atggctgaat cttttttata
    17041 atacagataa ttttacggta gaattctgtc atcagttcag actggataaa tgggataaaa
    17101 gtcgtgaaga tgccattgca aaagccggtt ctcaggaaag atgggcagag attacaagaa
    17161 ataaatatct ggatccatca ggcaacagtt attgtccgaa ctttaaagga cagaaatact
    17221 gcaaagcata tgcatatttt gattttacat cctattgttt cggtgatgtt gagatgaaaa
    17281 aagcgcctga gaaacgtgtg ggagaggcaa actgtacatg ggaacaggca gctgccacat
    17341 caaaagaaaa accttttggc attcgtcagg gacaggaatt ccagtatatg atccgggcgg
    17401 aggtgacacc caatagactg aaatcctttg tggtacagga tatacttgag gattgtctta
    17461 ctatagagga tgcatcaaaa gtcagtattg tgaatgatgc agggcagaca gtgacagact
    17521 ggtttgatgt tgctgttgaa ggacagaaag tgacctgcag ggccaaagca gagagccttc
    17581 aggatgaagc atttacagat aatcagactt acacatttac tttaaaagta cgccagagac
    17641 cggaatcaga aattaacatt tcaaaatacc ttgcagagga tggatacagt attcttgtac
    17701 caaaccatgc atccatgagt tatgaacgta caaacggaag cggagataca atggatacgg
    17761 aaacagtgtg ggtaaagggt gtgattccac cggaactgga agtaaagaaa aatacttctc
    17821 agtatgaatg gaaaacggga gatatcatag attatgaggt tctggtttct cagacaaaac
    17881 aggatgtaaa agcagtaaat gttgttatta cagacgagct tccatcatgt ctgcagtttc
    17941 tggaagggca gtatgctgta gagacaagtc agggaggcga gaactgtacg cttaccggac
    18001 agggagaaaa tggatggaaa gcagagtgtc cgtccctgaa gtatggggag acgatcacaa
    18061 tccgttttaa atgtcaggca tctgcggatt ccaatggaca ggaatgggaa aatattgtga
    18121 ctgcaacagc ggataatctg atcaatcctg agacaggaga acaggaatcc agaaaggata
    18181 tggcagaagt atggccgaac agtccacagc ttgaaattga taaaacagca gacaaatatg
    18241 aatggcaggc aggagagcag gtagcttacc ggatcgtggt gaataatgta acggcaggaa
    18301 caattgcaaa agatgtaact attactgata ttggtctgcc gcagggactg gttctggcag
    18361 gtggtgcaca gagcatggaa gtactgggag ttcagcaaca ggtaaactat cccgtaccgg
    18421 ataagaaaac aggacaggca tatgaagcga gatctgtgga ttctcagttg aatgcagatg
    18481 agaacggatt ttccttttat tgttcttatg tgccatacag tcagcctgta acgattattt
    18541 tccattgtat cgcacaggaa gaggcaaatg gacacgaaag cgtaaatgca gcaactgtaa
    18601 aagctgctaa tacagatgag agatctgatg atgcagaagt atatgtaaat tcaggagaat
    18661 tctggattga gaaatctgca gatcattatg aatggcaggt cggagaacag gtacagtaca
    18721 atgtggtggt ggagaataaa aaagcaggta cagtggcccg gaacgtaact gtctgggata
    18781 ccggtatgcc ggcaggactt gcgctttcat cggcagagga tgtatcggta agcggaatcc
    18841 cacagaatat tacgcagctg acagcaggga ccaaagatgt tttgaaccag ctcaatccgg
    18901 aattttataa tgagacatca gagaaaccgg tgaattatga atttcttcag gagggaagcg
    18961 gatggagact gaacatttca gatcttccgg caaatactcc ggttatgatt tctttccttt
    19021 gcacagttgc ggaagcggca aatggaatgg aaagcattaa tgttgccaat gtgcaggcgc
    19081 agaatgcccc tgtttcacag gatgacgcag aagtgtatgt aaatacagca gttctttcta
    19141 ttgagaaaag ttttcagaat ccatatctgg cagccgggga cggacgtgcg gaaaatgaat
    19201 ttcgggtagg agaacaggtg aattatcagg ttacggttaa taatcttcag aagggatcta
    19261 tcgcaagaaa tcttgtgatc agtgatcttt cccttcctga agggctggct ctggacggag
    19321 ctgaagatgc tgttactgta agcggtgttc cggctgttat tcagaatccg gtggcaggaa
    19381 ctgatgatgc aggaaatcag ctgaatccgg aaaattataa agaaacagtg gaaaaaccgg
    19441 tcagctgtca ggttacacgt cagggaaccg gatggatcgt gacgatttca gatcttccgt
    19501 atcagacacc tgtgactgtt aatttccgct gtactgcgca ggaaagcgta aatgggatgg
    19561 agattgtaaa tacagcacag gcgtatgcag ataatgcaca gaaagtaaag gactcctcaa
    19621 aaatctgggt gaactcgcct gttcttaacg tagagaagac gacggacaaa ccattttaca
    19681 aatatggtga tattattaca taccgcattg tcctgacaca ggagcagacc ggatgtgtgg
    19741 cgcgtaatgt tactctgcag gatgtgatcg atactcaggg agtacgtctt ctgaaggatt
    19801 cggtgattct gatggatgag aaaggaaatg tggcagatgc tgatgtacag atcaatgatg
    19861 ataatacttt cctgatgtca acaggcagga cactggtcag ggacagcaga tatagtatct
    19921 gcgataatga taaaggcggt ctttttgagc aggtaatgta taatcctctg gactgtcagg
    19981 aacagaaaag tatgatcgtg gaatatcagg cagcagtgat tgatgcagcc ctggcaggac
    20041 agaaagtgca caatactgca gttgcagaca gcagtgaaaa gatacctgca accggggaaa
    20101 cagagacaga ggtacacagt ccgattctgg aaattgtgaa ggaatcagat aagaaagagt
    20161 atgcgtccgg tgagaaagga tactataagc tgacagtaag acaactgcgt gaggatgtca
    20221 cagatcagaa tattgttatc gaagataaac tggaaaccca aggggcttct attgtaaaag
    20281 acagcatttt tgtgaagaaa aacggcatag agctgaaaga tgccaaaata gaggcagatg
    20341 atacaggatt tgtaattcag acaggagcat cgttgtcaga tatggataaa attgaagtct
    20401 gctatgaagt ggtatttaaa acagaaagca cagagcctga aaaaattgta aacacagcga
    20461 aagcaagagg agatatttca ccggaaattg cggcgcagca ggaggtatat gtgaaaacaa
    20521 aagcagaacc cactgccaca ccaacaccgt ctgcaacacc gaaaccaaca gaaacaccaa
    20581 agccgacaga gacaccaaaa cctacagaag taccgaaacc gacggagcag ccaaaagcca
    20641 caccaacacc atctgtaccg ggaacctgcc cgaaaatgac tcctgtaccg acgaaagcac
    20701 cgttggcatc ttacaatggt ggaaataatg gaggcacaac ttccggaaac ggaggcagca
    20761 gttacggaaa ttcgggtgga tacggaagct atcagggtgg ttccatggca ggaagttcta
    20821 aaacaggaga tgtcagaccg tttaaaatga tggctgttct tggacttatc ggaatgggac
    20881 tgctgacagg aggtgtggtg atctacagaa gaactgtttc cgggaaaaga aatataaagg
    20941 gtatgccgcg gaaatgaaaa aactcagaac atttgcagta agtatgatca tagcagcaat
    21001 tgggcttctt atatattgtg ccggcttcta tataaaaagt tatgaacaga atcttgcagc
    21061 aaggcaggaa tatgcagagc tttccaaaat ggcaggggtg aagaacagag caggtgccgg
    21121 attattggca gatggcaaaa aaactgatga agacagcagt acaaaaaaca gtgaaaaaaa
    21181 acgcaggaaa aaacagagaa gatcttctga atcaaaaaac aaaaactgta cagatgaaat
    21241 cagggaatcc ttcgggattt cctgggaaaa tttaagaaag atcaactctc agacagttgc
    21301 ctggattact gtcccgggag ccgatatttc ttatcctgta gttcaggcgg cagatgatga
    21361 atattacctg aaacataatt tcagaggaga ggaagatctg tttggatgta tttttctgga
    21421 acatgacata aaaaagaatt tcacagattc ccacagtatt ctttacgggc ataatataga
    21481 aggtaatatg atgtttgcaa atctgaaccg ttatgaacag cctgaatttc taaaaaaatg
    21541 tcctgaaatt gagatcacaa caccaaaaag aaagtttctg tacaaaattt tttctgtgga
    21601 acaggcatct tcccaaagcc cggcatttga atatggatac aagttatcca gtcctgcata
    21661 caggagacaa ttatctatat tgaaaaataa ttccatgtat gacacaggag tagagcctga
    21721 tgaaagggag agaatggtga ctctgatcac ctgtaattca cgtctggata aagaaatacg
    21781 tatggcggta catgggattt gccatgaatg ttatggtata gaaaaagctg agccgaagtg
    21841 atgttgaaat caatcggata ttggtaactt tcgtaaagga tgaactgtta ctgttcacac
    21901 atcactatcc ctcgaggtgt tttggaaaaa actaatgaaa aatctctcga tattttgtat
    21961 aatttatgca taaaaaacaa cttgttcgta cgtgcgtaca agttgtatcc taaatacagg
    22021 agggaagaag acatgacaga taatggaaag ccgaaatatt tctcactgat ggaacagctc
    22081 agaagtgata ttatgtcagg agctatccga ccgggagaga agcttccttc agaaaacgag
    22141 ctttcacaga aatattcctt gagtagacat acagttcgta aagcactggg aatcctggag
    22201 caggacggat atgtagaggc atttcacgga agaggtactt attgctctga gaatatgcgc
    22261 catataaaga attcaaagaa tattgcggta gtgaccacat atatttctga ttatattttt
    22321 ccgagactga tacagggaat ggataatgtc ctttcagaaa gcggttacag tattatcctg
    22381 aaaaacacag caaacagcag acagaaagag gccagatgtc tggaggaact tctgaagaaa
    22441 gatattgatg gactgatcat tgaaccaagc aaaagtgaga tgatctgtaa acacagaaat
    22501 ctttatcaga atctggataa atttgaaatt ccgtatgtgt ttattcaggg aatctattca
    22561 gaaatgaggg ataaacctca tattcttatg gatgatgcac agggaggcta tcttgtaaca
    22621 aaatatctgc tggaactggg acataaaaag atcaagggtt tctttaaggc agacgatatg
    22681 cagggactgg agcgccacaa gggatatgtg aaggccttac aggagtcagg gattgcctat
    22741 gatcctgatg atgttgtctg gtttcataca gaggacagga aagtaaaacc tgcactgatg
    22801 gcaaaagaaa tggtacagag cggacagctt ccggatggaa tcgtctgtta caatgatcag
    22861 attgctgttc aggttatgga agaactggag aaaatgggag tcaggatacc ggatgatatt
    22921 tccattaccg gttatgacaa ttcactgtat gctcagcgag gaagcggaat cacaacgata
    22981 gctcatccgc aggaaaagct gggagaaatg gcagcagagc ttatacttga gaagatcaac
    23041 ggagttcctg aagaagaaag taaggttgaa agactgattt atccggaact gatcatacgg
    23101 ggatcatgca gaaaaatatt gtaaacaaat gaaataaata aaaaataaaa ataaatccgg
    23161 gaggaatttt atcatgaaaa caggaagaaa ctataagttc tggttttgta caggttcaca
    23221 ggatctttac ggagatgagt gcttaagaa
//
