LOCUS       c00012_gnlPro..        14359 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BKDGDBGM_12.
ACCESSION   c00012_gnlPro..
VERSION     c00012_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 11:39:33
            Original ID  :: gnl|Prokka|BKDGDBGM_12
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 943196
            Orig. end    :: 957555
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14359
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[953196:956249]"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_AA_metabolism"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..13053
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /neighbourhood="10000"
                     /product="OD_AA_metabolism"
                     /protocluster_number="1"
     cand_cluster    1..14359
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(minimum(1, [PFOR_II, POR, POR_N]) and
                     minimum(2, [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE,
                     BcrAD_BadFG, Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /kind="single"
                     /product="OD_AA_metabolism"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14359
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="OD_AA_metabolism"
                     /region_number="2"
                     /rules="(minimum(1, [PFOR_II, POR, POR_N]) and minimum(2,
                     [ALS_ss_C, AlaDh_PNT_C, Arginase, BKACE, BcrAD_BadFG,
                     Beta_elim_lyase, CPSase_L_D2, Cys_Met_Meta_PP,
                     ELFV_dehydrog, GRDB, Glu_syn_central, Glu_synthase,
                     Gly_reductase, HAAA1, HG2B1, HG2B2, HGD-D, HleuD1, HleuD2,
                     HleuS1, HleuS2, Homoserine_dh, ILVD_EDD, IlvC,
                     Lactoyl-CoA1, Lactoyl-CoA2, Lyase_aromatic, MAAL_C,
                     OKR_DC_1_5_lysine, OKR_DC_1_5_ornithine,
                     OKR_DC_1_7_arginine, OKR_DC_1_C, OTCace, PALP,
                     Proline_reductase, Sacchrp_dh_C, TPL, Thr_dehydrat_C, TnaA,
                     Urocanase]) and not (Gly_radical_scatole or Gly_radical or
                     Gly_430_pcre or Gly_8-9_TMA))"
                     /tool="gutsmash"
     CDS             complement(1180..1962)
                     /locus_tag="ctg12_955"
                     /transl_table=11
                     /translation="MRKKNFTSMGMACLLGCCLMLGSCSSEVDNLDIPKGKGFVKIDLA
                     PEVGFQTKAVDESEYKDVNNYTVQVFKSGQEENLIINDLYKNLEEKYSLNVGNYVLKAF
                     TGEDKPVSSDVLYFSGEAAFEVKEGKEVTAPVICKPSSARINVVFDPKMDEYFSDYSLK
                     IETEAQKPSSFVWAKATVGPMYFKVGNQEKVQVTVSLTKKENVKAEGTVKTYTLSPADA
                     LKLTLKPVVNNGNLGISITIEETTVDHPVDIVIPGDWV"
     CDS             2927..3775
                     /locus_tag="ctg12_956"
                     /transl_table=11
                     /translation="MENDIPKIDLPQDWVIGKLSIEDIGLLNLYANYPCRLKAGIFVLC
                     LGGEIEASINLTQLKVEPGSFITIMPGSILQIHRADGDLQIYFMGFSSDFLSQANSSKA
                     VIDMHYIVKDNPVYKLKEKAQPLMKDYFELLLKTYEFYATKINRGITNHLFTGMLMGIS
                     SMYKDQTEDLSMLSKAELISKNFTQLVMQNYTMQRSVAWYAKRLGITQAHLSTIVKQST
                     GKTCIEIITSMVIMDAKAQLKSTNLTIHDIAYTLNFTNMSFFGKYFKRHVGMSPQEYRN
                     S"
     CDS             complement(4069..5607)
                     /locus_tag="ctg12_957"
                     /transl_table=11
                     /translation="MLVKSYAAAVQGISATVVTVEVNCSKGIQFFLVGLPDVAVRESHE
                     RIISALQVCGYKFPRNRIVINMAPADIRKEGSSYDLPLAIGILAAAEQIDSSNLSKFVL
                     MGELSMDGSLQPIKGALPIAIKAREEGFKGFILPKQNACEAAVVNDLEVYGASNIKEVL
                     EFMEGKPTLRPTVIDTRKEFYDRQQLFDCDFSDVRGQENVKRAMEVAAAGGHNLIMVGP
                     PGSGKSMLAKRLPTILPPFTLHESLETTKIHSVAGKIGGGTSLMVQRPFRSPHHTISNV
                     AMVGGGTFPQPGEISLAHNGVLFLDELPEFNRSVLEVMRQPLEDRVINISRARFTVEYP
                     AGFMLVASMNPCPCGYYNHPDRPCLCSPGAVQKYMNRISGPLLDRIDIQIEIVPVPFEK
                     ISEQQPSEPSIAIRERVIKARAIQERRFAAYEGIYCNAQMNSKLLHQYAVPDASGLSIL
                     KTAMQRLCLSARAYDRILKVSRTIADLDNSEHIEVRHLAEAIQYRSLDRENWGM"
     CDS             complement(5668..6768)
                     /locus_tag="ctg12_958"
                     /transl_table=11
                     /translation="MIKKLALIIGFIICLSSCGKDYVYRIEGELSNLEGQTVYAVFEKD
                     NYKVVDTVACTKPGQFQIDQNEAGFHCVTIFFADKEHWVTAYLEPGETVKITGDANSPL
                     LLQVKGGRTNDKLTAFKKKIAPLLTELTNLSNSLNSKDLNDTIEETDIAARLANVNMQL
                     SEEAIRYVKENPDEEASVVLIQSFFSDPDDTRKIDELLALLNPRLKDFYLVKELEQYSA
                     RAKRTALGAEAPDFSVRNIYGNTVSLDSFPQKYLLLTFTAPWCDMCQTEDLYLDKVAMK
                     YPKDQLDILLVSLDDNPDNVRDVLKKDSIAWNLVTDSAGQAAMLIDLYNVSVLPRCFLI
                     DEDHKILMKTENGIEIKQTLENLFED"
     CDS             complement(6958..8565)
                     /locus_tag="ctg12_959"
                     /transl_table=11
                     /translation="MANLDLSKYGIVDVKEIVHNPSYDVLFAEETKPSLEGFEKGQVTE
                     LGAVNVMTGIYTGRSPKDKFFVKNEASEDSVWWTSDEYKNDNKPCSEAAWADLKAKAVK
                     ELSGKRLFVVDTFCGANEATRLKVRFIMEVAWQAHFVTNMFIRPTAEELANYGEPDFVS
                     FNAAKAKVDNYKELGLNSETATVFNLKTKEQVILNTWYGGEMKKGIFSIMNYLNPLRGI
                     ASMHCSANTDKEGKSSAIFFGLSGTGKTTLSTDPKRLLIGDDEHGWDNEGVFNYEGGCY
                     AKVINLDKESEPDIYNAIKRDALLENVTVAADGKIDFADKSVTENTRVSYPIYHIENIV
                     KPVSKGPHAKQVIFLSADAFGVLPPVSILTPEQTQYYFLSGFTAKLAGTERGITEPTPT
                     FSACFGAAFLSLHPTKYGEELVKKMEMTGAKAYLVNTGWNGSGKRISIKDTRGIIDAIL
                     DGSINEAPTKKIPYFDFEVPTALPGVDPKILDPRDTYADPAQWDEKAKDLAARFQKNFA
                     KFTGNEAGKALVAAGPQL"
     CDS             complement(8981..9997)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg12_960"
                     /sec_met_domain="TPP_enzyme_C (E-value: 4.7e-30, bitscore:
                     100.3, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTTEETKFQPKDYKSDQYVRWCPGCGDHAVLNCLHKAMAEVGVAP
                     HNMAVISGIGCSSRLPYYMNTYGFHTIHGRGAAIATGVKTARPDLSVWLITGDGDCLAI
                     GGNHFIHAVRRNIDLNIVLFNNKIYGLTKGQYSPTSDRGFVSKSSPYGTVEDPFIPAEL
                     ALGARGNFFARTIDVDLKNTTEVLTASARHKGASVTEVLVNCVIFNDGIHKGIVDKEYR
                     ADRTIFLRHGEKMVYGANMDKGLVLDGLKLKSVTIGQDGYTMDDVLVHDAHEKDNTLHM
                     MLAMMSGDMPIALGVIRDVEGPTYDEAVHQQIEEVQAKNPTRKLHDLLMKGEIWEVK"
     CDS             complement(10001..11854)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: POR"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: POR_N"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Transketolase_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_961"
                     /sec_met_domain="POR_N (E-value: 2.8e-53, bitscore: 176.9,
                     seeds: 31, tool: rule-based-clusters)"
                     /sec_met_domain="POR (E-value: 6.6e-31, bitscore: 103.6,
                     seeds: 86, tool: rule-based-clusters)"
                     /sec_met_domain="Transketolase_C (E-value: 5.8e-07,
                     bitscore: 25.3, seeds: 80, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAEQTKVKTLEKVVIRFSGDSGDGMQLTGTIFSNLSAVFGNEIST
                     FPDYPAEVRAPQGTLSGVSGFQVHLGSRKIFTPGDKADVLVAMNPAALKVNVKHLKPNA
                     IVLIDTDSFKKSDLDKALFTTDDPFTELGLTGVQVVAAPISTMVKDGLVEFGLDNKSAL
                     RCKNMFALGLVCWLFERPLEEAMHMLQNKFAKKPVIAQANIKALTDGYNYGNNIHASVS
                     TYRIESKKAEPGFYTDVNGNKATSYGLIAAAEKAGLQLFLGSYPITPATDILHELSKRK
                     DLGVITVQAEDEIAGICTSIGASFAGCLAATSTSGPGLALKSEAIGLAVIAELPLVIID
                     VQRGGPSTGLPTKSEQTDLMQALYGRNGESPAVVIAASTPTDCFDAAFWAGKLAVEHMT
                     PVILLTDAFIANGSSAWRIPEMDKYPEIKPNYVANYQDEKVWKAYRRNKESLVRYWAIP
                     GTEGFAHRLGGLEKDYETSAISTDPANHQKMVTTRQAKIDKIADYIPELEVIGDEDADL
                     LIVGWGGTYGHLYETMETMQENGKKVAFAHFKFINPLPKNTAEVLSKYKKVVVAEQNNG
                     QFANYLRGKVPGFNPYRFNRVKGQPFVVARLVEEFTKILEV"
     CDS             complement(11943..12401)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: AlaDh_PNT_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_962"
                     /sec_met_domain="AlaDh_PNT_C (E-value: 3e-28, bitscore:
                     94.4, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLHNAFRSADVVIGAMRYINTRHRYIIATDLVRTMKKGALVIDLR
                     VSQGGCFETTCCLSREDPAVFEQYGVLHYCKLNISNRVARTTSMAYSNIFVPLLLSLGD
                     AGSVQGMIKSDKGFRAGVYMYYGKTVNSYVSNHFNLSSNNLDLYLSAF"
     CDS             complement(12391..13053)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     OD_AA_metabolism: AlaDh_PNT_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg12_963"
                     /sec_met_domain="AlaDh_PNT_C (E-value: 8.1e-18, bitscore:
                     60.3, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VNNARRKKRLPLTPEAVDMLTDCGHRVLVESGAGLGINYSDNHFS
                     EAGAEIVDTPAEVFQADLILKILPPLPVEIALMRPRTTVFSLVQFNLFAQEAFELMMAK
                     RITAISYELMADEYNRFPVLNVTSEIEGAASITIASELLSNTQGGKGILLGGIPGVSPT
                     EVVIIGAGNAGTVAARAALALGASVKVFDDDINKLRIIQQVLGQGLFYFHVPSECAA"
     CDS             complement(13050..13157)
                     /locus_tag="ctg12_964"
                     /transl_table=11
                     /translation="MEANDGRKAQGAYIPQELLKEISKVNNRLRHRYSS"
     CDS             complement(14095..14358)
                     /locus_tag="ctg12_965"
                     /transl_table=11
                     /translation="SRCHCGNFSSESGPSLWETLYVANDAPGHYSLEVFDVSSGNVRHV
                     KSMVEWMNGDKKETFAGEPNGVTRSYGKIYVTNTGSRTDVVF"
ORIGIN
        1 atgtaccgga aattcatagc tcttttctcc accaacaggt aaagttacac ccattgacgt
       61 caacgtctct cctaaagctt catttcctat caatttaaac tcttcaccaa atagatcttt
      121 aactattgac gcaaaaagct catttcctcc ctttatcgcg acagtgatat ttttcaagcc
      181 ggcaggagtt gatataataa catttgcatt tttttgttca tcagcgggca acgtataaag
      241 agcttgcggt atcgtgattg tcggatcatc acccgtcacc ggtggtgtcg gaggttcagg
      301 attctcttcg ccactatcac cttccacttc tatatcaata ttctcatttg tctcttggtt
      361 aaaaccgtta accgtgatgg tgataccggt tttattgaga tccacttctt ttccgggagc
      421 caacgagatc gccaaaccat ctcctcctac aaaatagggg ctgtcgcttt ctacaaaatc
      481 agcactttcc ttcttcgtta atgtctgatt tataataact tcttcactcg tttccttcac
      541 tatagctgtt cccgacacat aaatcttatc tgtctcagca gccattttcc aataaatcgg
      601 agttgggttt ggattttctt gcgtataaat atctgaatga ccgcacttgt catccaccgt
      661 aatagaccat ttgctataat agtttataaa ctcggaggta aaatccatcg caattttgac
      721 attctggatc ttacatttca ccgtagcggt tttttccaca ctaggcatta tctctgcttt
      781 ttctacacct ccataataag gatcgtacat cttttcggca aactctcccg gcgaatgcgc
      841 ctctatctca taatttcctt tcggcaactc aatcacacca ttcgcatttt cttctttaaa
      901 cttagcaaac gactcatagt ttttagtaag atcaaaatcc atcgccttga tcacgagcgg
      961 aaaatcttct ttctgatcag ttgctccttt cgttgctaaa gaagcagagg aacctgcgct
     1021 cacgtcaagt gtcaaatagc cagtttcctt tgggatctct ttcccgaaaa tctcctcttt
     1081 catctcacac gacatcaagc cggaaaacaa aaccgtgctc aacatccata tattgatcgc
     1141 tttcatattc taatctctta ttattactgt tatatatatt tatacccaat cccccggaat
     1201 aacgatatct accggatgat caaccgtagt ctcctcaatt gtaatcgaaa ttcctaaatt
     1261 gccattgttg actactggtt tcaaagtaag tttcaaagca tccgctggac ttaacgtata
     1321 ggtcttaacc gtcccttctg cttttacatt ctctttctta gtcaagctta ccgtaacctg
     1381 gaccttttcc tgattaccta ccttaaaata catcggaccg actgtcgcct ttgcccaaac
     1441 aaaagaagag ggtttctgcg cctctgtctc aatcttcaag gaatagtcgg agaaatactc
     1501 atccatcttc ggatcgaaca caacattaat tcgagctgag ctgggcttac atattacagg
     1561 agctgtcacc tcctttccct ccttcacttc aaaagcagct tcgccagaaa aatacaacac
     1621 atcggaagaa accggtttat cttcacccgt aaaggctttc aacacatagt taccaacatt
     1681 caaagaatat ttctcttcca aattcttata caaatcatta ataataagat tctcctcttg
     1741 cccggattta aacacttgca cagtataatt gttcacatcc ttatactcac tctcatccac
     1801 ggcttttgtt tgaaaaccga cctccggtgc cagatctatt ttcacgaaac ctttgccctt
     1861 cggaatatcc aaattatcca cttcagagct acagctaccc aacatcaaac aacagcccag
     1921 taagcaggcc attcccatag atgtaaaatt ctttttcctc atataaatgc ttttttcaat
     1981 tacttcaatt cgtatagatc cattcgatcc caatttggat gcaaaagaat atatttcaca
     2041 aagatcctac aaggtctatt tgtcttatta cctattcctt tttttagatt ccatacctca
     2101 cccctacaca tacagagcca tttataaaga gtggccatgt tctattttta caacccattg
     2161 ttccttttat tagaaaccgt gcctaaacaa aatgcgctca gacaagagcc gcccctagag
     2221 aaagcaagat tacaagatag tcgcttcgat ggaagaaaaa aggatttgac aaaatggcaa
     2281 tttgtaatct caacctcttg agtatcgatt atttcggggc aaagtactac ttacttccaa
     2341 attcataaga gaaaatcagc aattatttga atgatagcca tatatcaaaa aacgacattt
     2401 tgttctagca aaaataattc atcgtaattc atattatggg gagtgagaga gggaaaaaaa
     2461 acagtcttac aatagggtta taacagtata agaatgccta ttcacgacta cttacacccc
     2521 tattcacgac tactcacgat gcccaacggc agtataggca ttgcccaatg ctgcctattg
     2581 catacatatt cgccgtctaa cgtgtaccga aaacgttact ttttaacata aaaggccact
     2641 tatcttcctg attctttcgc tattttgata ggtcaaggaa atacccctgt cacaatatac
     2701 atccaaattc aatcaaaacg aaacagaaaa gataattcta atggcaacta cttccttcga
     2761 caagaaacca taccagtcca gcccaaacac ccaagcgact ccgaaaagcc tccggaatac
     2821 cgcaagtttc agacgctcgt ataattttcc ttccacaaga cacggcaaat ctttaaaaat
     2881 gcctactttt gtcaaacgtt cccgataagt gaataattaa acaaacatgg aaaatgacat
     2941 tcccaaaata gacctgcctc aagattgggt gatcgggaag ctttcgatcg aagatatagg
     3001 cctgctgaat ctgtatgcga attacccatg ccgattgaaa gcggggattt tcgtgctatg
     3061 cctaggagga gagatcgagg catccatcaa cttaacgcaa ctcaaggtag aacccggaag
     3121 cttcatcacc atcatgcccg gatcaatcct gcagatccat agggcagacg gggacctaca
     3181 gatctatttc atgggattct catctgattt cctcagccaa gcgaactcca gcaaagctgt
     3241 catagacatg cattatatcg tgaaagacaa tccggtgtat aagctaaaag agaaagccca
     3301 gcctcttatg aaagattatt ttgagttatt actcaaaaca tacgagtttt acgccacgaa
     3361 aataaatcgc gggattacca accatttgtt taccggtatg ctgatgggga tcagcagcat
     3421 gtataaagac cagacggaag acctgtcaat gctctccaaa gcagagctaa tcagtaagaa
     3481 tttcactcaa ctagtaatgc aaaactatac catgcaacga tccgttgcat ggtatgccaa
     3541 gcggcttggc atcacgcaag cacacctaag tacgatcgtc aaacaaagta cgggaaaaac
     3601 ttgtatagag attatcacct cgatggttat catggacgca aaggcacaac taaaatcgac
     3661 gaaccttacc atccacgata tcgcctatac actgaatttc actaatatgt ccttcttcgg
     3721 aaagtatttt aaacgccatg taggtatgag tccgcaagaa taccgcaatt cctaaacaac
     3781 cctaaaaaag taagctagct tacttttaaa gaccttctgc tcggatatct tttcttgact
     3841 ggcatacagc acgttaaatc attcacaaaa ggcttcccaa gtgattagtt attcacttcc
     3901 caagccgtaa gctgaccacc aggtatagcc atcagttgtt cactcgacaa gccgtcagtt
     3961 attcacttca acagccataa atagcgcaat ttccaactaa tataaagata gttttttcag
     4021 cttagtaact gcactattat ggttaataga tgtattctaa gtgcaatctc acatccccca
     4081 attctcccta tccaaactcc tatactgtat cgcctccgcc aaatgccgga cttcgatatg
     4141 ttccgaatta tccaagtcgg ctatcgtgcg ggagactttc aggatacggt cataggcacg
     4201 ggcggagagg cagagacgtt gcatggcggt tttgaggatg gagaggccgg aagcgtcggg
     4261 aacggcgtac tgatggagta gcttggagtt catctgggca ttacaataaa taccctcata
     4321 agcggcaaaa cgcctttcct ggatcgcacg ggcttttatg acccgctcac ggatagcgat
     4381 actaggctct gagggctgtt gctcggaaat cttctcgaaa gggacaggga caatctctat
     4441 ctggatatcg atacgatcga gtaatgggcc ggaaatgcgg ttcatatatt tctggacggc
     4501 tccgggagaa cagagacaag gacggtccgg atggttgtag tagccgcagg gacaaggatt
     4561 catggaggcc acaagcataa agccagctgg atattccacc gtgaaacggg cacgggagat
     4621 attgatcact cgatcttcca atggctgccg catgacttcc aagacactcc tgttaaattc
     4681 cggcaactca tccaaaaaaa ggacaccatt gtgagccaag ctgatctctc ccggctgcgg
     4741 gaaagtgcca cctcctacca tagcgacatt agagatcgta tgatggggag agcgaaaagg
     4801 acgttgtacc atcaaggagg tgccacctcc tatcttaccg gctacggaat ggattttagt
     4861 tgtttccaag gactcatgca aggtaaaggg aggcaagatc gtagggagac gtttcgccaa
     4921 catggacttg ccacttccgg gaggacctac catgatcaga ttatgtccgc cggctgcggc
     4981 cacctccatc gcacgcttca cgttctcttg tccccggaca tcggagaaat cgcaatcaaa
     5041 caattgctgg cggtcgtaaa actccttacg ggtatcaatg accgtaggcc gcaatgtagg
     5101 tttcccctcc ataaactcca gcacctcttt gatattcgaa gctccataca cttccagatc
     5161 gttcaccacc gcagcctcac aagcgttttg cttgggtaag ataaagccct taaagccttc
     5221 ttccctagcc ttaatagcga taggcaatgc cccttttatc ggttggaggc tcccatccat
     5281 agaaagctcg cccatcaata cgaatttgga taagttggat gaatctatct gctctgccgc
     5341 cgccagaata ccgatcgcca aaggcagatc ataagaagac ccttccttac ggatatctgc
     5401 gggggccata ttaataacga tacgattgcg ggggaattta taaccacata cttgaagagc
     5461 cgagataatg cgttcatggc tctcacgaac ggccacgtcc ggaagaccga ctaaaaagaa
     5521 ttggatacct ttggaacagt tcacttctac ggtaacgacc gtagcggaaa tcccctgcac
     5581 ggcagcggca taagatttta ctaacatagt taagaatttt gagttactaa ttacaaatta
     5641 aaaccggaac ctcctgtttt caatcgctca gtcttcgaac aagttttcca gtgtttgctt
     5701 gatctcgatt ccattctctg ttttcatcaa gatcttatga tcctcatcta tcaagaaaca
     5761 gcgtggcaat acgcttacgt tatacagatc tatcaacata gccgcttgtc cggccgaatc
     5821 tgttaccaag ttccacgcta tactatcctt cttcagtaca tcccggacat tatccggatt
     5881 atcgtccaag ctaaccaaaa gaatgtccaa ctgatctttc ggatatttca tcgctacctt
     5941 atccagatat agatcctctg tctggcacat atcacaccaa ggagcggtaa acgtcagcaa
     6001 taaatatttc tgcgggaaag aatccaaact taccgtattc ccataaatat tccttacgga
     6061 gaaatctggg gcttccgcac ccaaagccgt acgtttcgca cgggcgctat attgctccag
     6121 ctccttcacc agataaaagt ctttcaacct tggattcaat aacgccaaca actcatcaat
     6181 tttacgagta tcatcgggat ctgagaaaaa agattgaatc aagacaacgg atgcctcttc
     6241 atccgggttc tctttcacgt accggatcgc ttcctcgctc aattgcatat taacattcgc
     6301 caaacgagcg gcgatatccg tctcctcgat cgtatcgttc aaatccttgc tatttaaaga
     6361 atttgataaa tttgtcaatt ccgtcaataa aggagcgatt tttttcttaa aagcggtcaa
     6421 cttatcattt gtccgtcccc cctttacctg caatagcaat ggagagttag cgtcgcccgt
     6481 gatttttacg gtttctcccg gttccagata agccgtaacc caatgctctt tatctgcaaa
     6541 gaaaatagtc acacaatgga aacccgcttc attttgatcg atctggaact gcccgggttt
     6601 cgtacaagcc acggtatcaa ccactttata attatccttc tcaaatacag catatacggt
     6661 ttgaccttcc agattagaaa gttccccttc aatccgatag acataatcct tgccacaaga
     6721 tgacaaacaa attataaagc caataataag tgccagtttt tttatcatta ctccttttta
     6781 agctcttctt ataacagata atccggtcta aaggtaggaa tatttttttt aactacttta
     6841 catttataat aaaattaacg tagttatcat aaaaaaagcg cagaattagt aattccacgc
     6901 ttttttataa agatattttt aaaccttgac cttttttgat caaggttttt taagcaatta
     6961 taactgagga ccagcagcaa ccaatgcctt accagcttcg ttgcccgtga acttagcaaa
     7021 gttcttctgg aagcgagcag ccaaatcctt cgctttctca tcccattgag caggatcagc
     7081 ataggtatcg cgaggatcta agatcttcgg atctacgccc ggtaatgcag tcggaacctc
     7141 gaagtcgaaa tacgggatct tctttgtcgg agcctcattg atagaaccat caaggatagc
     7201 gtcgatgata cctcttgtat ctttgataga gatacgtttg ccgctaccgt tccaacctgt
     7261 gttcaccaag taagccttag cgccagtcat ttccatcttc ttaaccaact cttcgccgta
     7321 ttttgtcggg tgcaatgaca agaaagcagc accgaaacaa gcggagaatg taggagtcgg
     7381 ttccgtgata ccacgctctg tacctgctaa tttagcggta aatccagaca agaagtagta
     7441 ttgagtttgc tccggagtca agatagatac tggaggcaat acaccaaatg cgtcagcaga
     7501 caagaagata acttgttttg cgtgcgggcc tttagaaacc ggcttaacga tgttctcgat
     7561 gtgatagatc ggataagaaa cacgagtgtt ctctgtaact gacttatcag cgaaatcgat
     7621 cttaccatca gcggcaactg ttacgttctc aagaagagcg tcacgtttga tagcgttgta
     7681 gatatccggc tcgctctctt tatccaagtt gataacctta gcgtagcaac caccctcgta
     7741 gttgaataca ccttcgttat cccatccgtg ctcatcgtca ccgatcaaca aacgtttcgg
     7801 gtccgtagac aaagtagtct taccagtacc agacaaaccg aagaagatag ctgagctctt
     7861 gccctcttta tccgtgttag cggagcagtg catagaagcg ataccacgca acgggttcaa
     7921 gtagttcatg atagagaaga tacccttctt catctcacca ccgtaccaag tattcaagat
     7981 aacttgctct ttagtcttca agttgaaaac agtagcagtc tcagagttca agcctaattc
     8041 tttgtagttg tcaactttag ccttagcagc gttgaaagaa acgaaatcag gttcgccgta
     8101 gttagccaat tcctcagctg tcggacggat gaacatatta gttacgaagt gagcttgcca
     8161 agcaacctcc atgatgaaac gtactttcaa acgagtagcc tcgttagcgc cacagaatgt
     8221 atcgacaacg aacaaacgtt tgccagacaa ttcttttacg gctttagcct tcaagtctgc
     8281 ccaagcggcc tcagaacaag gcttgttatc attcttatat tcatcagaag tccaccatac
     8341 agaatcttcg ctggcttcat tctttacgaa aaatttatct ttaggagaac gacctgtata
     8401 aataccagtc atcacgttta cagcacctag ctcagttact tggcctttct cgaagccttc
     8461 caaactcggt ttagtttctt ctgcgaacag aacatcataa gacggattgt gaacgatttc
     8521 tttcacatca acaattccgt acttgcttaa atctaaatta gccatcttga atttaattta
     8581 aatgattgac tttatataac ttttctctct actctagttc gatacggtga ggctttccga
     8641 ccttttggag cttgctgcga ctccaccttg ttaaccgcgg tacaaaagta atattttttt
     8701 tttatcgtac acagcttatt aaggaaattt ttcagtaata attactcttt tccatgcaat
     8761 taacaaaacc cttagtctat ttgtaatatg gagtttacaa atcatatact tttagctagc
     8821 atctcaacta tttccgaagt tgtcatcata ggtattcgct tttattgtga ctgaaacaaa
     8881 gatatatact tttttccgca caaacaaatc cagcgtataa atataagaaa ggcgcaggat
     8941 aaatatcttg cgccttctct tatatccaat cagaaatata ttactttacc tcccaaatct
     9001 cacctttcat caaaaggtcg tgtaatttac gtgtaggatt cttcgcttgt acctcctcga
     9061 tttgctggtg gacagcctca tcataggtcg gtccctccac atctcgtatt acgcctaacg
     9121 caattggcat atcaccgctc atcatggcaa gcatcatatg caaggtgtta tccttctcat
     9181 gggcgtcgtg taccaatacg tcatccatcg tataaccatc ttgtccgatc gttacggatt
     9241 tcagttttag gccatctagc acaagacctt tatccatgtt agcgccataa accattttct
     9301 cgccatggcg aaggaaaatc gtacgatccg cacggtattc cttgtctacg atacctttat
     9361 ggataccgtc attaaagatc acacaattca ctaatacctc cgtaacggaa gcgcctttat
     9421 gacgggcgga agccgtcaat acctcggtcg tattcttcaa atccacgtca atcgtacggg
     9481 cgaagaaatt accacgggca cccaacgcca actcggccgg gataaacgga tcttccaccg
     9541 tcccataagg agaactcttg gatacgaaac cacggtcgga tgtcggggag tactgtccct
     9601 tcgtcaaacc atagatctta ttgttgaaaa gaacgatatt caaatcgata ttacgacgga
     9661 cagcgtggat aaaatgatta ccgccgatag ccaagcagtc gccatcaccc gtaatcaacc
     9721 atacgctcaa gtccgggcga gccgtcttta cgccggtagc gatagccgct ccacgaccat
     9781 ggatcgtatg gaagccatac gtattcatat aataaggtaa gcgggaagaa cagccgatac
     9841 ctgagataac tgccatattg tgaggagcca ctcctacctc ggccatagcc ttatgcaggc
     9901 aattcagtac cgcatggtcg ccacaacccg ggcaccaacg tacgtactgg tcgcttttat
     9961 aatctttcgg ttgaaattta gtttcttctg ttgtcatctt ttaaacctcc aatattttag
    10021 tgaattcctc aactaatctc gcaacgacaa aaggttgtcc ctttacacga ttgaagcgat
    10081 acgggttaaa tccgggtacc tttccacgta aatagttagc gaactggccg ttattttgct
    10141 cagccaccac cactttctta tacttagaaa gaacctcagc cgtattctta ggcagcgggt
    10201 tgataaactt gaagtgagcg aaagccacct tcttgccatt ctcttgcatc gtctccatcg
    10261 tctcgtaaag gtgtccgtag gttccacccc aaccaacaat caataaatca gcgtcctcat
    10321 ctccgatcac ttccagttcg gggatatagt cggcgatctt atcgatctta gcctgacggg
    10381 tcgtcaccat cttctggtgg ttagccggat cggtagagat cgcactcgtc tcgtagtctt
    10441 tctccagacc gcccagacga tgagcgaaac cttccgttcc cggaatcgcc cagtaacgaa
    10501 ccaagctttc cttgttacga cgatacgcct tccagacttt ctcgtcttga taattagcta
    10561 cgtaattcgg cttaatctcc ggatatttat ccatttccgg aattctccaa gcggaagaac
    10621 cgttagcgat aaaggcatcg gtcaacaaga taaccggagt catatgctcc acggccaact
    10681 tacccgccca aaatgcggca tcaaaacaat cagtcggcgt agaggccgct attaccacgg
    10741 cagggctctc accattacgg ccatacagag cctgcatcaa gtccgtttgc tcgctcttcg
    10801 tcggcaagcc cgtagaagga ccgccacgct gaacatcgat aatcaccaaa ggcaactcgg
    10861 cgattacagc caaaccgatc gcctcgctct tcaaggcaag ccccggtccg gaagtagatg
    10921 tagccgccaa gcaaccggcg aaactagctc cgatagaagt acagataccg gcgatctcat
    10981 cctcggcctg aaccgtgata acgcctaaat ccttacgttt agataattca tgtaaaatat
    11041 cagtagccgg agtgatcggg taactaccca agaacaactg caaaccagcc ttctcggcag
    11101 cggctatcaa accataggaa gtagccttat taccattcac gtccgtatag aatccaggct
    11161 cggctttctt actctcgata cgatacgtag aaactgaggc atggatgtta ttaccataat
    11221 tataaccgtc cgtcaaagcc ttgatattag cttgggcgat aaccggtttc ttagcgaact
    11281 tattctgcaa catgtgcata gcctcctcca gtggacgctc gaacaaccag caaacaagtc
    11341 ctaaggcgaa catattctta cagcgaagag ccgatttatt gtccaaacca aactcaacca
    11401 atccgtcttt taccatcgta gagatcggag cggcaacaac ctgcacgcca gtcaatccca
    11461 gctcagtaaa cggatcatcg gtcgtaaaca aggccttatc caaatcactt ttcttgaaag
    11521 agtccgtgtc gattaaaaca atcgcattgg gttttaggtg ttttacgttc accttcagcg
    11581 cggcgggatt catggccacc aatacgtcgg ccttatcacc gggtgtgaag atcttgcgcg
    11641 atcccaagtg cacttggaat ccagatacac cacttagtgt tccttgtgga gcacgtactt
    11701 ctgccggata gtctgggaat gtagaaatct cgttcccgaa aaccgcggac aggtttgaaa
    11761 agattgtacc ggttaactgc ataccatctc ccgagtctcc cgagaaacga attacaacct
    11821 tctccagcgt cttaactttt gtctgttctg ccataatata ctttattagc tttatcgctt
    11881 attggtattt agatcgtccg caaagtaaag cataaacttt gcgagttcaa aacttttccg
    11941 catcaaaaag cagagaggta tagatcaaga ttattagatg atagattaaa atggttagac
    12001 acataactat tcactgtctt cccataatac atatatactc ccgccctaaa gcccttatcc
    12061 gatttgatca ttccttgcac ggaaccggcg tcgcccaacg acaataataa aggtacgaat
    12121 atattactat aagccatcga ggtagtacga gccacccggt tgctgatatt cagtttacaa
    12181 taatgtaata ccccatattg ctcgaacacc gcaggatctt ccctcgacaa gcagcaagtc
    12241 gtctcaaagc aaccgccttg gcttaccctc agatcgatca ccaaagctcc ctttttcatc
    12301 gtacgcacca agtccgtagc gataatatag cgatgtctcg tattaatata acgcatcgcc
    12361 ccgatcacca cgtcagcgct acgaaacgca ttatgcagca cattcggatg gaacgtggaa
    12421 gtaaaaaagc ccttgcccca agacctgttg tattatacgc aatttattga tatcatcatc
    12481 gaatactttc acggatgctc ccaaggccaa cgcggcacgc gcggccacgg tcccggcgtt
    12541 tccggccccg ataatcacca cttctgtagg ggatacgccc gggataccgc ctaataagat
    12601 ccctttacct ccttgggtat tgctcaacag ctcggaagcg atcgttatgg aagccgcccc
    12661 ctcgatctcg gaagtgacat tcagcaccgg gaaacgatta tattcatccg ccatcaactc
    12721 ataagagata gcggtaatcc gtttcgccat catcaactcg aaagcctctt gagcgaataa
    12781 attaaactgc accaatgaga aaacggtcgt gcgaggtctc ataagtgcga tttccaccgg
    12841 caacggaggc aatatcttca agatcagatc cgcttggaaa acttctgcgg gcgtatcgac
    12901 gatctccgcc cccgcctccg agaaatgatt atcggaatag ttgataccta atccggcgcc
    12961 actttccacc agcacccggt gaccgcaatc ggtcagcata tccaccgcct ccggagttaa
    13021 cggcaaacgt tttttccgcc tcgcattgtt cacgaggaat accgatgacg caaacggtta
    13081 ttcaccttgc tgatctcttt caataattcc tgcgggatat aggccccctg tgccttccgg
    13141 ccgtcgttcg cttccatatg ctataggatt ttcattaacg cgttccctcg tgaagcatat
    13201 ccgttctatc tctcggaaag cctcctcccc tctctcaggc gaatatctgc gaaacggcct
    13261 tatgataaac gcccttcgat atagtaatca agatctatga acgaaagacc ggcgagcttg
    13321 gcaagctctt tttattctcc accgttgtct tgccgctccc atatatccga ccaaaaaaac
    13381 acgttcatac gttattataa tagttttcgc aaatgtaaac tttttccggg aactccatct
    13441 tctttttatt cctaagaatt caatcaaaaa aaatcatagg ccaatggctt ttactgtcct
    13501 gggtcgcacg agctccacta ccacaataaa gtatgacgag caccggctat tttctcggga
    13561 tagaccatcg aatcagtaaa gtcctgcaat aattttcccg ttcttagggc tgatctccca
    13621 tagctccgac cgtttatcat cgacacgaag cgtaaacaaa caaacgatcc cctacaaacc
    13681 gctatcgact gcgggagact tttcaaattc ccagtggtca ccagatacgg cgcaaaagcc
    13741 ggggtcccct gcctgaatgt ccccgcagga tcgaataaat aagagtatat ttttattctg
    13801 ggccgtcaca tataaaaagg cctatcattt cgtgccgcta ctgcataagt acccattgcc
    13861 tacttgtaaa tttacgctac ggctatatat aggtacccga gcagcggaac cggggctgta
    13921 catcttgctc caatacaaac taccagtttt ccggggggtg tatacacgga taaagacagc
    13981 cccttgaact atccggtcac cattcaaaac gcatgaacgg tcctgaaata tacccacccc
    14041 tcaccccaat tacccgtacc gatacaaagt aatgaactca tacgtttccg acaatcaaaa
    14101 aaccacatcc gtacggcttc ccgtattcgt gacatatatt ttcccatacg agcgagtcac
    14161 gccgtttggc tcccccgcaa aggtctcttt cttatctccg ttcatccact caaccatact
    14221 tttcacatga cgcacattac cggaagatac atcaaagacc tccaaactat aatgtcccgg
    14281 agcgtcattt gctacatata gcgtttccca taaagatgga ccgctttcgg atgaaaagtt
    14341 tccacagtgg caccgggaa
//
