LOCUS       c00105_gnlPro..        14358 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LNGBEAJH_445.
ACCESSION   c00105_gnlPro..
VERSION     c00105_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 14:03:22
            Original ID  :: gnl|Prokka|LNGBEAJH_445
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14358
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14358
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[1811:4358]"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1812..4358
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /neighbourhood="10000"
                     /product="Fumarate2succinate"
                     /protocluster_number="1"
     cand_cluster    1..14358
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Succ_DH_flav_C and FAD_binding_2 and
                     (Fer2_3 or Fer4_7 or SucD_FumR))"
                     /kind="single"
                     /product="Fumarate2succinate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..14358
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Fumarate2succinate"
                     /region_number="1"
                     /rules="(Succ_DH_flav_C and FAD_binding_2 and (Fer2_3 or
                     Fer4_7 or SucD_FumR))"
                     /tool="gutsmash"
     CDS             complement(420..641)
                     /locus_tag="ctg105_1"
                     /transl_table=11
                     /translation="MLQSILWFKEGGEKRKDLRIKRLLFLTPIFTFFIFLDEAGNLPAV
                     LVKWPQAHDTESFSMVPLNETPADNRSC"
     CDS             complement(658..882)
                     /locus_tag="ctg105_2"
                     /transl_table=11
                     /translation="LKDNDFTHKPLLTKREKEVFELLVQDKTTKEIASELFISEKTVRN
                     HISNAMQKLGVKGRSQAVVELLRMGELKL"
     CDS             complement(1237..1713)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HBT_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg105_3"
                     /sec_met_domain="HBT (E-value: 1e-17, bitscore: 55.5,
                     seeds: 132, tool: rule-based-clusters)"
                     /sec_met_domain="HBT_2 (E-value: 3.2e-17, bitscore: 54.3,
                     seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LKKHISYIDDWEAWEEGFSFYLPVTVRFSETDMFGHMNNTVPFIY
                     FEQARIEFLQQLGFMGDWAKRGTGSIPVVADLQCDFLQQVFFNDKLRIYVKVSKIGNSS
                     VDLHYMAKNEADEICFTGRGTMVQISAATGKGKPWTAEEKARFADPQAYVSSGN"
     CDS             complement(1812..2579)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Fer2_3"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1052:Succinate dehydrogenase-2Fe-2S iron-sulfur
                     cluster binding domain (Score: 100.1; E-value: 2.2e-31)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg105_4"
                     /sec_met_domain="Fer4_10 (E-value: 8.9e-12, bitscore: 36.2,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="Fer2_3 (E-value: 1.2e-31, bitscore: 100.1,
                     seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.00016, bitscore: 13.4,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGEQKTVTFIIQRQDNPESEPYDETFEVPYRPNMNVISALMEIRR
                     NPVNAKGEKTTPVVWEMNCLEEVCGACSMVINGKPRQACSALVDKLEQPIRLAPMRTFP
                     VVRDLQIDRSRMFDSLKKVKAWIPIDGTYDLGEGPRMPEKKRQWAYELAKCMTCGVCLE
                     ACPNVNSRSNFIGPAPLSQVRLFNAHPTGHMNRDERLEAIMVDGGLANCGNSQNCVQVC
                     PKGIPLTTSIAALNRETTIYMFKKFFGSDHTVD"
     CDS             complement(2652..4358)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: FAD_binding_2"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Fumarate2succinate: Succ_DH_flav_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1027:FAD binding domain (Score: 273.2; E-value:
                     1.4e-83)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg105_5"
                     /sec_met_domain="FAD_binding_2 (E-value: 7.4e-84, bitscore:
                     273.2, seeds: 62, tool: rule-based-clusters)"
                     /sec_met_domain="Succ_DH_flav_C (E-value: 4.3e-48,
                     bitscore: 153.7, seeds: 739, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LMATVKIAEAGRQVDLFSLVPVKRSHSVCAQGGINGAVNTKGEGD
                     SPWIHFDDTVYGGDFLANQPPVKAMCEAAPGIIHLFDRMGVMFNRTSEGLLDFRRFGGT
                     QHHRTAFAGATTGQQLLYALDEQVRRHEVDGLVTKYEGWEFLGIIKDDEGICRGIVSQN
                     LTTMEIKAFPADAVIMASGGLGIIFGKSTNSMINTGSAASIVYQQGATYANGEFIQIHP
                     TAIPGDDKLRLMSESARGEGGRIWTYKDGKPWYFLEEKYPAYGNLVPRDIATREIFHVC
                     VDLKLGINGENMVYLDLSHKDPHELDVKLGGIIEIYEKFVGDDPHKVPMKVFPAVHYSM
                     GGLWVDYKQHTSIPGLFAAGECDYSMHGANRLGANSLLSAIYGGMVAGPEAVNYIDGLE
                     KSANALPSTVFERAVQEQEKKWNDILSLDGTENAYVLHKELGEWMTDNVTVVRYNDRLK
                     KTDEKIQELMERWKNINVVDTSKWSNQAASFTRQLYNMLQLARVITIGALNRNESRGAH
                     YKPDFPDRNDEEWLKTTMANYDPVNNEPVFSYEDVDVSLIKPRVRDYTKKH"
     CDS             complement(4475..5083)
                     /locus_tag="ctg105_6"
                     /transl_table=11
                     /translation="VAGNREFYNRKLHSLLGVVPIGLFLVIHLTVNHYAVNGAAAFNKA
                     AGFMENLPFLLFVEVVFIYLPLLFHAIYGLYISFTASSNVGTMGYFRNWMYLLQRISGV
                     LVLIFLVFHIYETRIQMALGKELNFDLMANLLANRWMLAWYIIGTVAAIFHFANGLWSF
                     LVSWGITQSRRSQQISTYVMIVVFVLLSVVGVRALLAFA"
     CDS             5512..5970
                     /locus_tag="ctg105_7"
                     /transl_table=11
                     /translation="VKSSGGNEQTVAEQLMVPTFGYELLRNILIPDILGKETPDILYWA
                     GKHLARKFQLLTYEEMVSFFKEAGWGTLSIKKEEKYHIEFELSGPMIERQLDMGAGAEP
                     TFKLEAGFLAEQYQMQKKLITEAVEEVAKKAKKIRITVQWDAKDPAEE"
     CDS             complement(6010..7239)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AA_kinase"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg105_8"
                     /sec_met_domain="AA_kinase (E-value: 3.4e-58, bitscore:
                     188.1, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="LGIIVQKFGGTSVGNVERIRNTVDRIIEEKEKGHDVVVVVSAMGK
                     TTDQLVGLANELSAYPAKREMDMLLSTGEQVTISLVAMALIDRGYDAVSYTGWQAGIIT
                     EPVHGNARITEIRTEKIKSRLAAGQIVVVAGFQGITPEGEIATLGRGGSDTTAVALAAA
                     LHADRCLIYTDVTGVFTSDPRYIPTARKLKAVSYDEMLELASLGAGVLHARAVEFAKNA
                     AVPLIVCSSLEREEGTLIEEEVSVEKNLIVRGVAFEDGITRVTIFGLENGFRNLPDIFT
                     TLAEHHIDVDIIIQNRTADHKTYLSFSIKDKDLKETADLLEAGKEALSIDHFETETGLA
                     KVSIIGSGMVSNPGVAAKMFQVLADHGIAIKMISTSEIKVSTVVDAKEMVRAARCLHEA
                     FELDAVEQNI"
     CDS             complement(7426..7611)
                     /locus_tag="ctg105_9"
                     /transl_table=11
                     /translation="MAGFVSDFRERISRRPAKPLHDRGAKLKSKEREKIGLPGSFLKGS
                     FAEVEMASMPFLLVLY"
     CDS             complement(7657..9429)
                     /locus_tag="ctg105_10"
                     /transl_table=11
                     /translation="LNETIRNKLALLPAQPGCYLMKDRQGTIIYVGKAKILKNRVRSYF
                     SGSHDAKTQRLVSEIEDFEYIVTSSNIEALILEINLIKKHDPKYNIMLKDDKTYPYIKL
                     THERHPRLITTRKVKKDKGKYFGPYPNVQAANETKKLLDRLYPLRKCTNMPDRVCLYYH
                     LGQCLAPCVNEVKEETYKEITDQITRFLNGGYTEIKKELEEKMHEAAEKLEFERAKEYR
                     DQIANIEMTMEKQKITMTDFTDRDIFGYAVDKGWMCVQVFFMRQGKLIERDVSLFPSYD
                     EPEEEFLSYLGQFYAKPEHIKPKEVLITEKADRELAEQLLEIKVLQPKKGQKRELVLMA
                     EKNAKIALKEKFALIERDEERTIKAVENLGEKLGIYTPHRIEAFDNSNIQGTNPVSAMV
                     VFVDGKPAKKEYRKYKIKTVEGPDDYESMREVIRRRYIRALRENLPLPDLIIIDGGKGQ
                     IDAARDVLENELGLEIPLGGLAKDEKHNTSQLLFGNPLEVVPLGRNSQEFYLLQRIQDE
                     VHRFAITFHRELRGKSAFQSALDDIPGIGPKRKKQLLRHFGSLKKMKQAKLEEFVEAGI
                     PRPVSETLIKKLQE"
     CDS             complement(9534..9749)
                     /locus_tag="ctg105_11"
                     /transl_table=11
                     /translation="MIAPVLEEIDAEMGDKVKIVKVDVDENQETASKFGIMSIPTLVLM
                     KDGKPVDKVIGYQPKEALQELVNKHL"
     CDS             complement(10034..11014)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF_alpha"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 147.9;
                     E-value: 9.8e-46)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg105_12"
                     /sec_met_domain="ETF (E-value: 5.2e-46, bitscore: 147.9,
                     seeds: 129, tool: rule-based-clusters)"
                     /sec_met_domain="ETF_alpha (E-value: 1.1e-38, bitscore:
                     122.4, seeds: 511, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSRKVLVVGEVRDGSLRNVSYETIAAGKTVAEGGEVVGVLIGDAV
                     KDLGKDMIQYGADRVAVVEDEKLKSYSSDGFSQALLAVVESEKPDGILIGHTALGKDLA
                     PKVAAKLDAGLISDATAVESAGEHVVFTRPIYSGKAFEKKIVTDGIIFATIRPNNISPL
                     EKDESRTGDIETVQAEIKDLRTVIKEVVRKVSEGVDLSEAKVIVSGGRGVKSADGFKPL
                     KELADVLGGAVGASRGACDAGYCDYSLQIGQTGKVVTPDLYIACGISGAIQHLAGMSNS
                     KVIVAINKDPEANIFNVADYGIVGDLFEVVPLLTEEIKKLKVTSA"
     CDS             complement(11045..11818)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ETF"
                     /gene_functions="electron_transport (smcogs)
                     SMCOG1008:Electron-transferring flavoprotein (Score: 170.7;
                     E-value: 9.7e-53)"
                     /gene_kind="electron_transport"
                     /locus_tag="ctg105_13"
                     /sec_met_domain="ETF (E-value: 5.2e-53, bitscore: 170.7,
                     seeds: 129, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIFVLLKRTFDTEEKIAIANGRIQDDGAEYIINPYDEYAVEEAI
                     QVRDAQGGEVTVVTVGNEDAEKQLRTALAMGVDKAVLINIEDDVEASDQVTTSKVLAAY
                     LKEQEPDLIIGGNVAIDNASGQVGPRVAELLGIPYVTTITNLEIDGGKATVTRDVEGDS
                     EIIETDLPLLVTAQQGLNEPRYPSLPGIMKAKKKPLEELELDDLDLEEEDVEPKTKTIE
                     VYLPPKKEAGKVLEGEIADQVKELVQLLHAEAKVI"
     CDS             complement(11880..12653)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ECH_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg105_14"
                     /sec_met_domain="ECH_1 (E-value: 2.5e-68, bitscore: 221.1,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEFITIKRENAVACIEMNRPPANALAQALLKELAQAFGQLENDPE
                     TRVVLLYGKGRFFSAGADIKEFVQLRESGGSDAIAVSGQELFEKVEAFPKPVIAAIHGA
                     ALGGGLELAMACHIRLVTENAKLGLPELSLGLVPGFAGTQRLPKYIGRGKAFEMLWTSE
                     PLTGTEAVQQGLANHAYKEEELLPKAKALAEKIAKKSPLALKASIELVNYAKTNDYEKG
                     LEQESARFLELFGSKDAEEGIKAFIEKREPRFTGA"
     CDS             complement(12688..13236)
                     /locus_tag="ctg105_15"
                     /transl_table=11
                     /translation="VVVIAQHGYHQAQVSKIAKQAGVADGTIYLYFKNKEDILISLFEE
                     KMQLFIEKVSEYIAGDLSPSEKLLKMIENHFKVLAADHHLAVVTQLELRQTNLDLRLKI
                     NSVLKEYLTLFDQIIREGMEKGEFDSGLDVRLVRQMIFGTVDETVTTWVMNKEKYDLVS
                     LAAPVHQLIINGCGKKTAV"
ORIGIN
        1 gagaaaagga ttggaaaaat aactttggct aaagccaacc gaaattcatc tcccacctac
       61 tcattggtgc gattcgcacc ttcacattcc ttgaggatgg gagacttctt tcggaaagcc
      121 gttaaattgc gatgtttgcg gataaatcta ttaatctctc ctgaaaatat gcgccggctg
      181 gctttcatcc ttctgctggt gccgcattca ttcggcatgg gcgtctgttt gcaaatttgg
      241 gtgcagcagc gtttgattta aagccaaatc gtccaacgtc tttggagaaa acttcacact
      301 gcctcatgag ggctttggaa aaaattttaa tgccgtcttt tgagataaca acgccgtttg
      361 ttttcgtaag cctcgtgatt ttttatacgg tatccggcgt ctggacgccc cgccttttac
      421 taacatgatc gattgtcggc cggagtttca tttaaaggca ccattgaaaa cgattccgtg
      481 tcgtgagctt gtggccattt tactaaaacc gccggcaaat ttccagcttc atctaaaaat
      541 atgaaaaatg taaaaatcgg agtcaaaaag agtaaacgct ttatccgcag atccttccgt
      601 ttctctcccc cctctttaaa ccacaaaatc gactgcaaca ttgcagccga ttttgtttca
      661 aagctttaat tcccccatgc ggagtaattc aacaacagct tgcgagcgcc ccttgactcc
      721 caatttctgc atggcattgg aaatatgatt tcgaactgtt ttttcgctga taaacaattc
      781 gcttgcgatt tcttttgttg tcttgtcttg tactaacagc tcgaatactt ctttttctct
      841 ttttgtcagc agcggtttat gtgtgaaatc gttgtccttc aactatgata accctccttg
      901 ccttcgccag ctctaaaccg cggggatggg tattttggtt gtcacaatat cttatgtttt
      961 agcgcagccg ggagtgactt ggcgaggcaa ggaacagcac aaatcagcaa aaaagggcgg
     1021 ataccggaaa tcccttctgt gcaaaagaag aatgaagcat tatccggcat tgtaaactgg
     1081 cagttatgga ttctgtttat ggcctgtacg aagacggcaa agcaggcaag caattgttgt
     1141 aaaaaatacc acgtattgcc gctcttttct ccgctcgaat taatccccaa cgcacgcact
     1201 taagtttata ttatacggcg ggatggactc tttcgttcag ttgccggatg agacataagc
     1261 ttgcgggtcg gcgaatctcg ctttttcttc cgccgtccac ggttttcctt ttccggttgc
     1321 ggccgaaatt tgcaccattg tcccgcgccc ggtaaaacag atttcatccg cttcattttt
     1381 cgccatatag tgcaagtcaa cggacgaatt gccgattttc gagactttta cataaatgcg
     1441 gagcttgtca ttgaaaaaaa cctgctgcaa aaaatcacac tgcaaatccg ccacgaccgg
     1501 gatggatccg gtgcctcttt ttgcccagtc gcccataaac ccgagctgct ggagaaattc
     1561 aatccgcgct tgttcaaaat aaataaacgg aacggtattg ttcatatggc cgaacatatc
     1621 ggtttcggaa aaacggaccg tcaccgggag ataaaacgaa aatccttctt cccaggcctc
     1681 ccagtcatca atataagaga tatgtttttt caatggaatg cctcctttta atgagtgaac
     1741 agccattcat tttttgtttg aaaaagagcg ccacatcgta ctgtttccgc tttgatgtgg
     1801 cactttcggc attagtcaac cgtatggtca ctgccaaaga attttttaaa catataaatg
     1861 gttgtttcac ggtttaacgc tgcgatggat gttgtcagcg ggataccttt cgggcagact
     1921 tgcacacagt tttgcgagtt gccacaattg gcaaggccgc cgtcaaccat gatcgcttca
     1981 agccgttcat cacggttcat atgaccggtc gggtgcgcat taaataaccg tacttgcgaa
     2041 agcggggccg gcccgataaa gtttgaacgg ctgttgacat tcgggcaggc ttccaaacat
     2101 acgccgcacg tcatgcattt tgccagttca taagcccact gccttttttt ctccggcatg
     2161 cgcggccctt cccctaagtc gtaagtgccg tcaatcggaa tccaggcttt cacttttttc
     2221 agcgagtcga acatgcggct gcggtcaatt tgcaaatctc ttacaaccgg gaaggtccgc
     2281 atcggggcaa ggcggatcgg ctgctccagt ttgtccacaa gcgctgaaca agcctggcgc
     2341 ggcttgccgt taatcaccat ggaacaggcg ccgcaaactt cttccaaaca gttcatttcc
     2401 caaacaacag gtgttgtttt ttcccctttg gcattgaccg gattccggcg gatttccatc
     2461 agggccgaaa tgacattcat attcggccgg tacggaactt caaacgtttc gtcgtatggt
     2521 tctgattccg gattatcctg gcgttgtatg ataaatgtaa cggttttttg ttcacccatc
     2581 cttattctcc tctttcctta tgaaatcacc cgggcaaaag ccggaaaaag tccgctttcg
     2641 cccgatccga atcagtgctt cttcgtgtag tcgcgcacgc gcggcttgat cagcgataca
     2701 tccacatctt catagctgaa aaccggctca ttgttcacag ggtcataatt tgccatcgtc
     2761 gttttcagcc attcttcgtc gttgcggtcc ggaaaatcag gtttatagtg ggcgccgcgg
     2821 ctttcattac ggttcagggc gccgatcgta atgacgcgcg ccagctgcag catgttatac
     2881 agctgccgtg taaacgaagc cgcctggttg ctccatttcg atgtatctac aacattaata
     2941 tttttccatc tttccattaa ttcctgaatc ttttcgtccg ttttcttcag acggtcattg
     3001 taacggacaa ccgtcacatt gtctgtcatc cattcgccca gttccttatg caacacatag
     3061 gcattttcgg ttccgtcaag cgacaatata tcgttccatt ttttctcctg ttcctggaca
     3121 gcacgttcaa agacggttga cggcagtgca ttcgcgctct tttcaagccc gtcgatgtag
     3181 ttgacagctt caggcccggc taccatcccg ccatagatgg cagaaagcag ggagtttgcc
     3241 cctaagcggt tcgcgccgtg catcgagtag tcgcattcgc ctgctgcgaa cagccccgga
     3301 atgctcgtat gctgcttata gtccacccat aatccgccca tggaatagtg gacggccggg
     3361 aatactttca tcggcacttt atgcgggtca tcgccgacaa atttttcata gatttcaata
     3421 atcccgccca gtttaacgtc cagttcatgc ggatctttgt gcgacaaatc gagatagacc
     3481 atgttctcgc cgttaattcc gagtttcaag tccacgcaga catggaaaat ttcacgggtt
     3541 gcaatatcgc gcggcacgag gttcccgtat gccggatatt tttcttccag gaaataccac
     3601 ggtttgccgt ctttgtacgt ccagatgcgc ccgccttccc cgcgtgcgga ttcactcatc
     3661 agccgcagtt tgtcatcacc tgggatagca gtcgggtgga tctggataaa ttcgccgttc
     3721 gcatacgttg cgccctgctg gtatacaata gaagccgccg agccggtatt gatcatcgag
     3781 ttggtcgact tcccgaaaat aatgccaagg ccgcctgatg ccataatgac agcatccgca
     3841 ggaaaagctt tgatttccat tgtggtcagg ttttgcgaaa caatgccgcg gcagatgcct
     3901 tcatcgtctt tgataatgcc gagaaattcc cagccttcgt atttcgtgac aagcccgtcc
     3961 acttcatggc gccttacctg ttcatccaat gcgtataaaa gctgctggcc ggttgtcgcg
     4021 cctgcaaatg ctgtgcggtg gtgctgggtg ccgccgaaac gcctgaagtc caaaagccct
     4081 tccgacgtgc ggttgaacat gacacccatc cggtcaaaca agtggataat ccccggcgcc
     4141 gcttcgcaca tcgcttttac cggcggctgg ttggcaagga agtcgccccc gtataccgta
     4201 tcgtcaaagt ggatccatgg cgaatcccct tccccttttg tattgacagc gccgttaatg
     4261 ccgccctgtg cgcaaacaga gtgcgacctt tttaccggca ctaaagaaaa cagatcaacc
     4321 tgccggcctg cttctgcaat ttttacagtc gccatcaaac cggcaagccc tccgccgaca
     4381 acaatgattt tgccattagc caacttgatt cactcccttt tcatacttga tgcctcttac
     4441 aaaccagtag actgctattt ttcgagtctt ttcattatgc aaatgctaat aaagccctga
     4501 cgccgacaac ggaaagcagc acaaagacca cgatcatcac atatgtggaa atttgctgtg
     4561 accggcgtga ctgtgtaatg ccccagctga ccaggaacga ccagagaccg ttggcaaagt
     4621 ggaaaatggc agccactgtc ccaattatgt accaggcgag catccaacga tttgctaaaa
     4681 gatttgccat cagatcaaaa ttcaattcct tgccaagcgc catttgaatg cgtgtttcat
     4741 agatgtgaaa tacgagaaag atcaggacca gcacaccgct gattctttgc aataggtaca
     4801 tccagttccg gaagtagccc atcgtgccga cattgctcga tgccgtaaac gaaatgtata
     4861 agccgtaaat tgcatggaac agaagcggca gataaatgaa tactacttcc acaaaaagca
     4921 ggaacggcag gttttccata aaaccggctg ctttattgaa ggcagcagca ccgtttaccg
     4981 catagtggtt tacggtcaag tggatgacta aaaataagcc gatgggtaca acacccagca
     5041 aagaatgcag tttgcggtta taaaactctc gatttccagc cacattgtat ccccctttgt
     5101 agtgtgaatt tatgcaaaga agacaaattt tgcatggctt cctcccgcat aaatatttta
     5161 taacaattat gtgacagttt tattgtactc ccgacaaatg ggcacgtcaa ggaaacgcat
     5221 tcatgaattt gcgctgaaaa tgccgtttat ttgtcatatt tgtcagtctt tcttccattt
     5281 ttttaaaatt ttttcagtat agctcttttg ccatatgctt ttgcataaaa aaggaatttt
     5341 tatccaaggc ttgtcttttt tcatcggatt ttaccgcaac cggtaccact tccccgtata
     5401 acgcggaaac cggcggaaaa agttcctttt atttttgtgt atacttaaaa aatgctttta
     5461 agtccggttt tattttgtat ataatatagc atatagaaag aggggaattg cgtgaaatct
     5521 tctggcggaa atgaacaaac cgttgcggaa cagctgatgg tacccacatt cggatatgag
     5581 ctgttgcgca atatattaat tccggatata ctcggcaagg aaacgccgga tattctgtac
     5641 tgggcgggaa aacatttggc aagaaaattc cagttgctta cctatgaaga aatggtttct
     5701 tttttcaaag aggccggctg gggaacgttg tcaatcaaaa aagaagagaa atatcatatt
     5761 gaatttgagt tatccgggcc gatgattgaa cggcagctgg atatgggcgc aggcgcagaa
     5821 ccgacattca agcttgaagc cgggtttttg gccgagcagt accagatgca gaaaaaactg
     5881 atcacggaag ctgtggaaga agttgcgaaa aaggcaaaaa aaatccggat caccgtgcag
     5941 tgggatgcga aagacccggc cgaggaataa atatgaaaaa gcagggggct cccctgcttt
     6001 ttcatatttt catatatttt gttccactgc atccagttca aatgcttcat gcaggcaccg
     6061 ggcggcccgg accatttctt ttgcatcgac aacggtggat actttgatct cggacgtgct
     6121 gatcatttta atcgcaatgc cgtggtcggc cagaacctgg aacatttttg ccgcaacgcc
     6181 tgggttggaa accatgcccg agccgatgat ggacactttt gcgaggccgg tttccgtttc
     6241 aaaatggtcg atgctgaggg cttctttccc ggcttccaaa agatcggccg tttcttttag
     6301 atctttatct tttatcgaaa atgataaata tgttttatgg tccgccgtcc ggttctggat
     6361 gatgatatcg acatcaatat ggtgttccgc cagtgtcgtg aatatatccg gcaaattccg
     6421 gaagccgttt tccagcccga aaatggttac ccttgtaatg ccgtcttcaa atgcaacgcc
     6481 gcggacaatt aaattttttt ccaccgaaac ttcctcctct attaacgtgc cttcctccct
     6541 ttcaaggctc gaacaaacga tcagcggcac agccgcattt ttggcaaact ccaccgccct
     6601 tgcatgcagg acgcccgccc cgaggctcgc cagttcaagc atctcatcgt aggatacagc
     6661 cttaagcttc cgggcagtcg gaatatagcg cgggtcggac gtaaacacgc cggttacatc
     6721 cgtgtagatc aggcagcggt cggcatgaag cgctgctgca agcgccactg ccgttgtatc
     6781 cgagccgccc ctgccgagcg tcgcaatttc gccttccggg gtaatgccct gaaacccggc
     6841 gacaacgaca atttgcccgg ctgccagacg ggatttgatt ttttcagtcc ggatttccgt
     6901 gatccgggcg tttccgtgca cgggttccgt tataatgccg gcctgccaac cggtataaga
     6961 aacggcatcg tagccgcgat cgatcagcgc catggcgaca agcgaaatcg tcacctgttc
     7021 gccggttgaa agcagcatat ccatttcgcg ttttgcagga tacgccgaaa gttcatttgc
     7081 aagcccgaca agctggtccg ttgttttgcc catcgcggag acaacgacga caacatcatg
     7141 gcctttttcc ttttcttcaa taatccggtc gaccgtattc cggatccttt ccacatttcc
     7201 aaccgaagtt cccccgaatt tctgaacaat gattcccaat aactccgcca ccttctgcag
     7261 tttataagta agatgaggct gtcagattga aagcaaagca acttggcgcc cattaaaaaa
     7321 aaagcaatga gaacggatat ctcatcgctt ttgcatacgc gggtacgcag ttattcctgt
     7381 gagatagcgc tccaagacat ttcatcctga cagttccgga cttcttcagt acagaaccag
     7441 caaaaacggc attgaggcca tttccacttc ggcaaaactt cctttcagga acgatcccgg
     7501 aagcccaatc ttctcccgtt ccttactctt aagttttgcg cctctatcat gtaacggctt
     7561 tgccggacgc cgggatatcc gctcccgaaa gtctgaaaca aagcctgcca tatgaaatta
     7621 tcatgattat accatatacg gaaaaaccct gctaggttat tcttgtaatt ttttgattaa
     7681 tgtttcggat accgggcgcg ggatgcccgc ttccacaaat tcttccaact tcgcttgctt
     7741 cattttcttt aaggaaccaa agtggcggag cagttgtttt ttccgtttcg gtccgatgcc
     7801 cggaatatcg tcaagcgccg attgaaatgc ggattttccg cgcaattccc tgtggaacgt
     7861 aatcgcaaac cggtgcactt catcctggat gcgctggagc aggtaaaatt cctggctgtt
     7921 ccgcccgagc ggcacgactt ccagcgggtt gccgaacaaa agctgcgatg tattgtgctt
     7981 ctcatccttt gccaggccgc cgagcggaat ctcaagcccg agctcatttt cgagcacatc
     8041 ccttgccgcg tcaatttgcc cttttccacc gtcaatgatg atgaggtccg gaagcggcaa
     8101 gttttccctc agggcacgga tgtaacggcg gcggatcact tcgcgcatcg attcataatc
     8161 atccggccct tccaccgttt tgattttata tttgcggtat tctttttttg ccggcttgcc
     8221 gtccacaaac acgaccatcg ccgaaaccgg gtttgtcccc tggatattcg aattatcgaa
     8281 cgcttcaatc cggtgcggcg tatagatgcc gagcttttcg cctagatttt caacggcttt
     8341 gatcgtccgt tcctcgtccc gttcaatcaa cgcaaatttt tctttcaaag caatctttgc
     8401 gtttttctcg gccattaaca caagttcccg tttctggcct ttttttggct ggagcacttt
     8461 gatttccagc agttgttctg ccagttcccg gtctgctttt tccgtaatca gcacttcttt
     8521 cggcttaata tgctccggtt tggcgtaaaa ctgccccaaa tagctcaaaa attcctcttc
     8581 cggctcatcg taagacggaa aaagcgagac atcccgttca atcagctttc cttggcgcat
     8641 gaaaaacacc tggacacaca tccagccttt atccactgcg tagccgaaaa tgtcgcggtc
     8701 cgtaaaatcc gtcatggtaa ttttctgttt ttccatcgtc atttcaatat tggcgatctg
     8761 gtcgcggtat tcttttgccc gctcaaattc aagtttttca gcagcctcat gcattttttc
     8821 ttccagttct tttttgattt ccgtgtagcc cccgttcaaa aagcgggtaa tttggtcggt
     8881 gatctctttg tatgtttctt ctttcacctc attgacacac ggcgcaaggc actggcccaa
     8941 atggtaataa aggcagacgc ggtccggcat attggtgcat ttccgcaaag gatacaaccg
     9001 gtccagcagc ttttttgttt cattggccgc ctgcacgttc ggatacgggc caaaatattt
     9061 tcccttatct ttcttcactt tccgggtggt gatcagacgc gggtggcgtt catgggtcag
     9121 cttaatatac gggtatgttt tatcatcttt tagcatgatg ttgtatttcg ggtcatgctt
     9181 tttgattaag ttgatttcaa gaataagggc ttcaatattg gaagaagtga caatatactc
     9241 aaagtcttcg atctcgctga caagccgctg cgtttttgcg tcatgcgaac cggaaaagta
     9301 agagcggaca cggtttttta aaattttggc cttcccgaca taaatgatgg tcccctgtct
     9361 gtctttcatt aagtagcagc cgggctgggc gggcaggagg gcaagtttat tgcggatcgt
     9421 ttcgttcaat ttttcttcac ctcaaaatcc tgcgttctgt aaaaaacccg gaccacagcc
     9481 ggtccggatt ttaaatgcat ttgctcacgg cttgaagccg cgcgtttatt gtattataaa
     9541 tgtttgttca ctaattcttg caaagcttct ttcggctggt aaccgatcac tttgtcgacc
     9601 ggtttgccgt ctttcatgag aacaagggtc ggaatgctca tgatgccgaa tttgctggct
     9661 gtttcctggt tctcgtcaac gtccactttg acaattttca ccttgtcgcc catttcagca
     9721 tcgatttctt caagtaccgg tgcaatcatt ttgcacgggc cgcaccatgt tgcccaaaaa
     9781 tccgttaata ccaaaccttg gctgacttcc tgatcgaaag tcgcgtcggt agcatgtgta
     9841 attgccatat tgaaagaacc ctcctaaatc aaactattac tgcttgggat tagtatatca
     9901 tcctttatca tatgttgcga acaatttgtc cggtccaggt aagcagtaat gattttatta
     9961 ttttataccc tttttccgcg aatatccaac agaaaacagg cccggaacga tttttttcgt
    10021 ccgggcccgg gatttacgcc gatgtgactt tcagtttttt gatttcttcc gtgagaagcg
    10081 ggaccacttc aaacaggtcg ccgacgatgc cgtagtccgc tacgttgaag atgtttgctt
    10141 ccggatcttt gttaatggcc acaatgactt ttgagttgga catgccggcc aaatgctgga
    10201 tggcgccgga aatgccgcat gcgatataca aatccggtgt caccactttg cccgtctgcc
    10261 cgatttgcag ggaataatcg cagtatccgg cgtcacatgc gccgcgcgaa gccccaaccg
    10321 cgccgccgag cacatcggca agctctttca gcggtttgaa gccgtccgcg cttttcacgc
    10381 cgcggccgcc tgaaacgatg actttcgctt ccgaaaggtc aaccccttca cttactttcc
    10441 ggactacttc tttgatgacc gtgcgcaaat ctttaatttc cgcctggacg gtttcgatat
    10501 cccctgtccg cgattcatct ttttcaagcg ggctgatgtt gttcggccgg atggtcgcaa
    10561 agatgatccc gtctgttacg atctttttct caaacgcttt gccggagtaa atcgggcggg
    10621 taaagacgac atgttctccg gctgattcca ctgcggtcgc atccgaaatc aggccggcat
    10681 ccaatttagc cgctactttt ggggccaggt ctttgccaag cgccgtatgg ccgattaaga
    10741 tgccgtccgg cttttcagat tcgacaaccg caagcaatgc ttgggaaaaa ccgtctgaag
    10801 aatagctttt cagcttctcg tcttccacca cggcaacacg gtcagcaccg tattgaatca
    10861 tgtctttccc caaatctttc acagcgtccc cgatcaaaac gccgactact tccccgcctt
    10921 ccgctaccgt ttttccggcg gcaatggttt catatgatac attgcggagc gacccgtcac
    10981 ggacttcgcc cactactaat acttttcgac tcatgctgat cccctccatt tccggtttct
    11041 tcgcttaaat cacttttgct tcggcatgca ataattggac aagttctttt acctggtcgg
    11101 cgatttcgcc ttcaagcact tttcctgctt cttttttcgg cggcaggtaa acctcgatag
    11161 ttttggtttt cggctccacg tcttcttctt caaggtcaag atcatccagt tccagttctt
    11221 caagcggttt tttcttcgct ttcatgatcc ccggtagcga aggataacgc ggctcattta
    11281 agccctgctg cgctgtgacg agaagcggaa ggtccgtttc aatgatttcg gaatcccctt
    11341 cgacatctct tgtgaccgtc gctttgccgc cgtcaatttc cagattggta attgtcgtta
    11401 catacgggat gccgagcaac tccgccaccc gcggtccgac ctgtccggaa gcgttgtcaa
    11461 tggcgacatt cccgccgata atgaggtctg gttcctgctc tttcaaataa gcggcaagca
    11521 cttttgacgt tgtgacctgg tcgcttgctt ccacatcgtc ttcaatatta atgaggactg
    11581 ctttatccac acccatcgca agcgccgtcc gcaattgctt ttcggcatct tcattgccga
    11641 ctgtgaccac tgtgacttcg ccgccctggg catcccgcac ctggatggcc tcttcaacgg
    11701 cgtattcatc gtacgggttg atgatatatt ccgccccgtc atcctggatg cggccgtttg
    11761 caattgcaat cttttcttct gtgtcaaagg tccgttttaa taatacgaag atattcatgc
    11821 cgttccctcc ctgaatcgtt aaaaaataaa atcatttaag cgcatacaaa ataaaaatgt
    11881 tatgcccctg taaaacgcgg ttcccttttt tcaataaaag ctttgatacc ttcctctgca
    11941 tcttttgagc cgaacagctc aagaaaacgt gcggattcct gctccaagcc tttttcgtaa
    12001 tcatttgttt ttgcataatt gacgagttca atagaggctt tcagggccag cgggcttttc
    12061 tttgcaattt tttcagccag cgcctttgct ttcgggagca gttcctcttc cttataagca
    12121 tggtttgcaa gcccctgctg cacggcctcc gttccggtca gcggttcgct tgtccacagc
    12181 atttcaaacg ctttgccgcg cccgatatac tttggcagcc gctgcgttcc ggcaaaaccc
    12241 ggcacaagcc cgaggctcag ttccggaagg ccgagcttcg cattttctgt gacaagccgg
    12301 atatggcatg ccatcgcaag ttcgagcccg ccgccaagtg ccgcgccgtg gattgcggcg
    12361 atgaccggtt tcgggaacgc ttccactttt tcgaacaatt cctggccgga aaccgctatc
    12421 gcatcggagc cgccggattc ccttaattgg acaaattctt taatatccgc tcccgccgag
    12481 aaaaatcttc ctttcccgta aaggagcacg acccgggttt caggatcgtt ttcaagctgg
    12541 ccaaacgctt gcgcaagttc ttttaaaagg gcctgcgcaa gcgcgttggc gggcggcctg
    12601 ttcatttcaa tgcaggcaac cgcattttcc cgtttgatcg taataaattc catcccgtct
    12661 ccaaccccct tgtgaaagct gcggcaatta aaccgccgtt tttttgccgc agccgttaat
    12721 gatcaattga tggacgggag cagccagtga aacgaggtcg tatttttctt tattcatcac
    12781 ccatgtcgtc accgtttcat cgactgtccc gaaaatcatc tgtcggacga gccggacgtc
    12841 aagcccggaa tcgaattcgc ctttttccat gccttcgcgg ataatttggt caaagagcgt
    12901 caaatattct ttcagcacgc tgttgatttt aagccgcagg tctaaatttg tctgccgcag
    12961 ttccagctgg gtcacgaccg ccaaatggtg gtcggcggca aggactttga agtggttttc
    13021 gatcatcttg agcaactttt cggaagggga aaggtcccct gcaatatatt cggaaacctt
    13081 ttcgataaac agctgcattt tttcttcaaa caaagaaatc aggatatctt ctttgttttt
    13141 aaaatacaaa taaattgtgc cgtccgctac gcccgcctgt tttgcaattt ttgaaacctg
    13201 tgcctgatga tagccgtgtt gtgcgataac caccactgct gcatcaataa tttgtttgta
    13261 ctttggcctg tttttcctca cgggctatca cctttcaatc tcatgatctg tcaatttggc
    13321 cggccggttt gatggcggcc ggaaaatgaa tgaccattca ttcatatttt catattatac
    13381 aggaatgcag catttgtcaa gtcctgttta taaaaaattt tccttaaccg atcttctctc
    13441 cttcattttc catcttttct ttttcttctg caaccaatga gcgccgcaaa attttcccga
    13501 cggccgtttt cggcagttca tcccggaatt cgtaaatgcg cgggacttta taggccgcca
    13561 gatattggcg cgcaaaccgg tccagttctt cttccgttac tgccatattc tctttcagca
    13621 caatataggc tttgacggtt tccccgcggt acgggtgcgg cacgccggcc accacggctt
    13681 cctggacggc agggtgctca tacagcactt cttctacttc gcgcggataa atattatagc
    13741 cgcctgcaat gatgatgtct tttttccggt cgacaatata aaaataacct tcttcgtcca
    13801 tataagccag gtcccccgta aacagccacc cgtctttcag cacttcctgc gtttcttccg
    13861 ggcggttcca gtagcctttc atcacttgcg gcccttttac cgccagctcg ccgacttcac
    13921 cgggcggcaa cggcctgccg tcttcgagcg accggatttc gcagtccgta tccggccatg
    13981 gcacgccgat gctacctttg acgcgttttc cccatacaaa attggcatgg gtgacgggag
    14041 acgattcact gaggccatac ccttccacaa gcttgccgcc ggttacctct tcaaatttct
    14101 gctggacttc taccggcagc ggggcagaac cgctgatgca tgcttcaatc gatgacaaat
    14161 catattcctt gattttcggg tggtttaaaa gcccgatata aatggttggc gcacccggaa
    14221 acagggtcgg ccgctgtttt tcgatcgtct tcagcagcga ctccgcatca aaacgcggaa
    14281 ttaaaatcat tttaaagccc tgcatgacag aaagaatcag cacggtcgtc atgccataca
    14341 cgtggaaaaa cggaagca
//
