LOCUS       gnlProkkaKGDADLMN_8    28251 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|KGDADLMN_8.
ACCESSION   gnlProkkaKGDADLMN_8
VERSION     gnlProkkaKGDADLMN_8
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:00:45
            Original ID  :: gnl|Prokka|KGDADLMN_8
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 90225
            Orig. end    :: 118476
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..28251
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="True"
                     /core_location="[20000:21419]"
                     /cutoff="20000"
                     /detection_rule="(LmbU or Neocarzinostat or bcpB or frbD or
                     mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      20001..21419
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(LmbU or Neocarzinostat or bcpB or frbD or
                     mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)"
                     /neighbourhood="20000"
                     /product="other"
                     /protocluster_number="1"
     cand_cluster    1..28251
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(LmbU or Neocarzinostat or bcpB or frbD
                     or mitE or vlmB or prnB or CaiA or bacilysin or
                     orf2_PTase)"
                     /kind="single"
                     /product="other"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..28251
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="other"
                     /region_number="1"
                     /rules="(LmbU or Neocarzinostat or bcpB or frbD or mitE or
                     vlmB or prnB or CaiA or bacilysin or orf2_PTase)"
                     /tool="antismash"
     CDS             25..1194
                     /NRPS_PKS="Domain: Aminotran_1_2 (39-213). E-value:
                     8.6e-11. Score: 33.4. Matches aSDomain:
                     nrpspksdomains_ctg8_93_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     430.7; E-value: 8e-131)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_93"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 1.1e-142,
                     bitscore: 468.4, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.9e-10, bitscore:
                     33.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVQKRSAFLPYSLPMIGKDEIQEVIDTLESGWLSKGPKVEAFEKA
                     FAAWTGAKHAIALNSCTAALFLALKAKGIGPGDEVITSAVTFSSTANTIVHTGAVPVFV
                     DIDPLTLNADPEKIEAAVTPRTKAIVPVHFAGQSCDMDQILAIAEKHQLFVLEDAAHAV
                     YTTYKQKMIGSIGDATAFSFYATKNLATGEGGMLTTDDDELADQIRVLSLHGMSKGAWN
                     RYSSNGSWYYEVETPGYKMNMFDLQAALGLHQLKRIDSMQQRRADIASRYQDAFRHMKG
                     LTIPHVSDDGRHAWHLYVLQIEEQEAGVSRNDLISALKDQYNIGTSVHFIPVPFHPYYQ
                     KTYGYKETDFPAAAAYYHRTVSLPLYPSMTDDDVEYVIAAVTDIVKGAD"
     aSDomain        142..663
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_93_Aminotran_1_2.1"
                     /evalue="8.60E-11"
                     /label="ctg8_93_Aminotran_1_2.1"
                     /locus_tag="ctg8_93"
                     /protein_end="213"
                     /protein_start="39"
                     /score="33.4"
                     /tool="antismash"
                     /translation="EAFEKAFAAWTGAKHAIALNSCTAALFLALKAKGIGPGDEVITSA
                     VTFSSTANTIVHTGAVPVFVDIDPLTLNADPEKIEAAVTPRTKAIVPVHFAGQSCDMDQ
                     ILAIAEKHQLFVLEDAAHAVYTTYKQKMIGSIGDATAFSFYATKNLATGEGGMLTTDDD
                     ELADQIRVLSL"
     CDS             1195..2058
                     /locus_tag="ctg8_94"
                     /transl_table=11
                     /translation="MYRLRENLAQDMIHTFLHQKGIQPEAYESSLCLLEENSLQGVILY
                     ENSSWESQLFRKNIINVKLAAANSAGQLKRLFQEFYVARRAAGTDFIFIKIPAEDIGAM
                     QVVQQLPNAYFVGSLLKLVSPVRVYNSTPPFEITEAGPGDTEAISRLARDAFTKSRYYQ
                     DPHLSYESANRLFEEWARNNAEGRASLQFAATYKGETVGFVQGLSKGDEFVLDLMAVKP
                     GFEGKGAGFHLAAHVIEQSLRFQHKTVSAGTQLHNVRAIRLYERMGFKADASYYYYHVW
                     PGKEAD"
     CDS             2058..3179
                     /locus_tag="ctg8_95"
                     /transl_table=11
                     /translation="MASCQIGTKSIGEGSPVFIIAEAGINHDGKLSQAFELIDAASEAG
                     ADAVKFQMFQADKMYQKDPGLYKTAAGKNVSIFSLVQSMEMPAEWIEPLLEYCKKKGVL
                     FLSTVCDEGSADLLYATSPSAFKIASYELNHLPLLKYVAGLKTPIIFSTAGADISDIQE
                     AYRTITGEGNTEIAIMHCVAKYPAPPEYSNLSVIPMLAAAFPDAVIGFSDHSAHPYDVP
                     CAAVRLGAKLIEKHFTIDKNLPGADHSFALNPDELKEMVAAIRSVEAELRQGHHAPVPE
                     VLSGSSHKTTTPIEGDIRRFAYRGIFSTAPIQKGECFTAENLAVLRPGQKPQGLHPRYF
                     ELLTDGARAVRDIPADTGITWDDLLTKGSPYDD"
     CDS             3172..3912
                     /locus_tag="ctg8_96"
                     /transl_table=11
                     /translation="MTDILFIIQARMGSGRLPGKVLKPIGGYTILDMIVKRVRQSAYYD
                     QSRDNLIVASSDSKTDDILSAHCISKNYRVHRGSEQRVLDRFAQVIEQVKPDIAVRLTG
                     DNPFVDPSLLDFLIQSHLDQHADYTYICGTPLGIGGEAVNARLLTEINADKTLADKYQE
                     HVTLLIRESPGKYRLLFPEPPQELRAPHLRMTVDTEEDYRLARELYVKAGSRPDIPAKE
                     LIHLLNSDPELRAINQMIRQKEAD"
     CDS             3914..4918
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glyco_tran_28_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_97"
                     /sec_met_domain="Glyco_tran_28_C (E-value: 1.4e-07,
                     bitscore: 24.5, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRILIFADGGRDIGMGHAVRMKLLAGAIKNNCSITFCTNKEASSY
                     LSSDQWEVIIKPDKGQKEFIVREINRQAPDLLIFDLLDMPCDWLEEVKKHSSARIVLFE
                     EKREHVIHLCDAVINGIYGGLKSRTVQMGSAAVYEGPEYMILHPGFEKAKQLYQLRKEC
                     RTILVSLGGSDPKKLVFKVMEACRRIPDIHRKRVIIVMGGAAPHADDVRAHLTQMPYAE
                     MVRQTNDMAALLSRADMAVVSGGITLYETICTGVPCIVLSQVEHQTETAEKFAARGAAV
                     HLGLGECISPDVLARHMSDMAADYPLRTGLHQNGKPLVDGRGIKRAAAILYDL"
     CDS             4946..5683
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 222.7; E-value:
                     9.8e-68)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_98"
                     /sec_met_domain="NTP_transf_3 (E-value: 7.1e-15, bitscore:
                     48.6, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGVILAGGTGSRLMPLTKAVNKHLLPVGPYPMIYWSIMKLEEAG
                     ITDILLITQKEYIPQFHKLLETGEELGVSITYQVQPAASGISDGLSYAKRFTGRDPFVL
                     LLGDNIFEDSLKPYTERFAKQGKGAKVLLKEVDDPERFGIAEIDEENKRIKSIIEKPEQ
                     PPTRLCVTGIYMYDAEVFSYIEQISPSKRGELEITDVNNLYIEHSELTYDVLTGWWVDA
                     GTHESLYLAGSLAHQALQKGQEH"
     CDS             5686..6633
                     /NRPS_PKS="Domain: NAD_binding_4 (6-183). E-value: 2.3e-19.
                     Score: 61.3. Matches aSDomain:
                     nrpspksdomains_ctg8_99_NAD_binding_4.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) NAD_binding_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score:
                     300.4; E-value: 2.8e-91)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_99"
                     /sec_met_domain="RmlD_sub_bind (E-value: 6.4e-25, bitscore:
                     80.7, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 6.6e-19,
                     bitscore: 61.0, seeds: 77, tool: rule-based-clusters)"
                     /sec_met_domain="NAD_binding_4 (E-value: 4.9e-19, bitscore:
                     61.3, seeds: 102, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPKSYLITGGAGFIGLTFTKMMLKETDAQITVLDNLTYASRPLEI
                     EALKKNGRFRFIKGDISEKEDIDKVFSQMYDAVIHFAAESHVDRSINQAEPFITTNVMG
                     TYRLADAVLQGKAGRLIHISTDEVYGDLAPDDPAFTETTPLSPNNPYSASKASSDLLVM
                     SYVRTHKLPAIITRCSNNYGPYQHHEKMIPTIIRHAVNGTPVPLYGDGMQIRDWLFAED
                     HCRAIKLVLEKGTLGAIYNIGGGNERTNKELASFIMKELGVEERFAHVEDRKGHDRRYA
                     INASKLKNELGWRQDVTFEEGMRRTIRWYTDSQD"
     CDS_motif       5695..5754
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_99_0001"
                     /evalue="2.20E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg8_99"
                     /protein_end="23"
                     /protein_start="3"
                     /score="17.1"
                     /tool="antismash"
                     /translation="SYLITGGAGFIGLTFTKMML"
     aSDomain        5704..6234
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_99_NAD_binding_4.1"
                     /evalue="2.30E-19"
                     /label="ctg8_99_NAD_binding_4.1"
                     /locus_tag="ctg8_99"
                     /protein_end="183"
                     /protein_start="6"
                     /score="61.3"
                     /tool="antismash"
                     /translation="ITGGAGFIGLTFTKMMLKETDAQITVLDNLTYASRPLEIEALKKN
                     GRFRFIKGDISEKEDIDKVFSQMYDAVIHFAAESHVDRSINQAEPFITTNVMGTYRLAD
                     AVLQGKAGRLIHISTDEVYGDLAPDDPAFTETTPLSPNNPYSASKASSDLLVMSYVRTH
                     KLPAIITRCSNNYG"
     CDS             6654..7502
                     /NRPS_PKS="Domain: NAD_binding_4 (52-158). E-value: 3e-09.
                     Score: 28.2. Matches aSDomain:
                     nrpspksdomains_ctg8_100_NAD_binding_4.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) RmlD_sub_bind"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1010:NAD-dependent epimerase/dehydratase (Score: 88.6;
                     E-value: 8.3e-27)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_100"
                     /sec_met_domain="RmlD_sub_bind (E-value: 3.7e-104,
                     bitscore: 340.7, seeds: 37, tool: rule-based-clusters)"
                     /sec_met_domain="Polysacc_synt_2 (E-value: 3.2e-10,
                     bitscore: 32.5, seeds: 77, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTKVLVTGAAGQLGRELCRQLKREGYEVIALTKAMMNISDQRSVR
                     HSFSHYKPDIVVNTAAYTSVDKCETELDKAYLINGIGAYYAALEAENTGAKFIHISTDY
                     VFSGKGTRPYQTDDPADPGTIYGKSKKLGEELIRLTGKNHTIIRTSWVYGSGGHNFVNT
                     MLKLADTHNQVRVVNDQVGAPTYTKDLAETVIGLFDRPPGLYHAANSGVCSWYEFAKAI
                     FEESGRTAAVLPVTTEEYGNETPRPAYSVLSLESIERQGLGMRHWREALHDYLQREGQC
                     K"
     CDS_motif       6666..6722
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_100_0001"
                     /evalue="2.30E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg8_100"
                     /protein_end="23"
                     /protein_start="4"
                     /score="17.0"
                     /tool="antismash"
                     /translation="LVTGAAGQLGRELCRQLKR"
     aSDomain        6810..7127
                     /aSDomain="NAD_binding_4"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_100_NAD_binding_4.1"
                     /evalue="3.00E-09"
                     /label="ctg8_100_NAD_binding_4.1"
                     /locus_tag="ctg8_100"
                     /protein_end="158"
                     /protein_start="52"
                     /score="28.2"
                     /tool="antismash"
                     /translation="PDIVVNTAAYTSVDKCETELDKAYLINGIGAYYAALEAENTGAKF
                     IHISTDYVFSGKGTRPYQTDDPADPGTIYGKSKKLGEELIRLTGKNHTIIRTSWVYGSG
                     GH"
     CDS             7499..7954
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) dTDP_sugar_isom"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_101"
                     /sec_met_domain="dTDP_sugar_isom (E-value: 4.5e-22,
                     bitscore: 71.3, seeds: 19, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIEGVKIKKLIKHSDDRGFFSELVRDDEHLLERFGQASWSKSYPG
                     VIKAFHYHEKQDDLWFFPTGHAQVVLHDLREESATKGETDVYYMGEDNPMLLLIPKGVA
                     HGYRVLGETPLTIIYFTTMSYNPDQPDEKRIPWNDDTIGFDWQTAHR"
     CDS             8165..8629
                     /locus_tag="ctg8_102"
                     /transl_table=11
                     /translation="MMLKRKSFSAFLISAAVFSSVFLPSFHANAQSAVIEAKTVNSTKE
                     YATSDIEVTYKPNALLAVGAVEFQFPAGFNATVRDSVNGRTLKETQILNYGKTVRLPLT
                     LDLLGASEYNLVLVRKNLPRAGAYTIKGDYVNGLGAGSLYAETKLVIDPR"
     CDS             8816..10102
                     /locus_tag="ctg8_103"
                     /transl_table=11
                     /translation="MSANPISKSNQKDEEKEVLNLFLSTQSIIKEALRKLGYPDNMYEL
                     MKEPMRLLTVRIPVKMDNGSVQVFTGYRSQHNDAVGPTKGGVRFHPEVSEEEVKALSIW
                     MTLKCGITNLPYGGGKGGIICDPRTMSFGELERLSRGYVRAISQIVGPTKDIPAPDVYT
                     NSQIMAWMMDEYSRLREFDSPGFITGKPIVLGGSQGRETATAQGVTICIEEAVKKKGIP
                     LENARIIIQGFGNAGSFLAKFMHDAGAKVIGISDAHGALYDPDGLDIDYLLDKRDSFGT
                     VTNLFSDVITNRELLEKDCDILVPAAISNQITAENAHHIKASIIVEAANGPTTIDATKI
                     LNERGVLLVPDILASAGGVTVSYFEWVQNNQGFYWSEEEVAGKLRSVMVNSFESIYQTA
                     HTHKVDMRLAAYMTGIRKSAEAARFRGWV"
     CDS             10310..11857
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aldedh"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1017:aldehyde dehydrogenase (Score: 528.3; E-value:
                     2.3e-160)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_104"
                     /sec_met_domain="Aldedh (E-value: 1.7e-159, bitscore:
                     524.1, seeds: 89, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTVSYAHEPFTNFQEETNKQSFQEALAYVNSQLGKHYPLIINGEA
                     IETDKKIISVNPADKKEVIGSVSAAGKELAEKAMQAALQAFQTWKKARPEHRANVLFKA
                     AAIIRRRKHEFSAYLVKEAGKPWKEADADTAEAIDFLEYYARQMLKLKDGSPVKSRDGE
                     YNQYHYEPLGVGIVISPFNFPLAIMAGTAAAAIVTGNTILLKPADAAPVVAAKFVDVMK
                     EAGLPDGVLQFIPGDGGEIGDYLVEHPKTRFVSFTGSRAVGCRIYERAAKVQPGQKWLK
                     RVIAEMGGKDTVLVDRDADLDLAASSIVYSAFGFSGQKCSAGSRAVIHQDVYDEVVEKA
                     VALTKSLTVGSPEDFDTYMGPVIHEASYNKVMNYIEIGKTEGKLLTGGEGDDSKGYFIQ
                     PTIFADVDENARLMQEEIFGPVVAISKARDFDHMLEIANNTDYGLTGALLSKTRAHIER
                     AREDFHVGNLYFNRGCTGAIVGYQPFGGFNMSGTDSKAGGPDYLILHMQAKTTSEAY"
     CDS             11929..13611
                     /locus_tag="ctg8_105"
                     /transl_table=11
                     /translation="MYQQLSKMLPEEKIEAITKSLVALNSINGTLGEGKKADYIKDMIK
                     SFPYFQENPSHVWEQAIPEDPYGRKNIFAFIEGNGESLNTVIYHAHLDTVGIEDFGPLK
                     DIAFDSDRLAEYFSNYEFDRDVQRDARSGEWMFGRGSVDMQSGIAVHLANLLHFSERRD
                     QLPGHILFMANPDEESQHSGILTSISELKRLKQEKQLRYLAAINNDFITPLYEGDTTRY
                     IYTGAAGKLLPCFAIYGREVHVGDTLSGIDPNLIASEITRRIHNNIHMAENIEGELVLP
                     PTCLYQRDNKEAYNVQTAVSSYVYFNYFIYEKTAKVVMDQLTAVADEACKETERKLSDY
                     YDEYCERTSLPKKEMSWNVQVYSLEDYLKRLRSRGIDPAQCIEQAFKTYEHLELRMRCF
                     KAVEELQKLDPEQGAKVIIFYAPPYLPHNYLKEESSRDRLLQHVIQEAVDKTAASTGET
                     FVFKKFFPYLADGSFLSLHETDEEVSAFTDNFPGWDVIGTIPFKEIRELNIPSVNIGVY
                     GKDGHKWTERVYKPYTFHVLPELIQQTTMHLLHSYRLDIRTNG"
     CDS             13636..15054
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1038:phenylalanine-specific permease (Score: 413.7;
                     E-value: 1.2e-125)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_106"
                     /transl_table=11
                     /translation="MQGDTNQTELQRTMKGRHLFMIALGGVIGTGLFLGSGFTISEAGP
                     IGAILAYVIGGFLMYLVMLCLGELAVAMPVAGSFQAYAAKFLGPSTGFTIGWMYAFSWA
                     NTVGLELTSAGILMQRWFPAVPIWVWCLVFGVVIFSINALSARSFAEMEFWFSSIKVMA
                     IVLFIILGCAAVFGFVGFNGGQTAPYLSNFTTDKGLFPNGAQAVLFTLVMVNFSFQGTE
                     LVGIASGESENPEKTLPRSIRNVIWRTLFFFVLAMFVLVSILPYQTAGVIESPFVAVLD
                     KIGVPYAADIMNFVILTAMLSVANSGLYASSRMMWSLSKTKMGPASLTKLTKKGVPLKA
                     LSITIAISGLSLLTSVFAAETVYVWLISISGMITVVAWMSICASQFVFRRRFLAEGGNL
                     KDLAFKTPLYPIVPILGFSVYGLILISLIFIPDQRIGLYCGVPLMIICYAYYHFGIKKR
                     LKREPASSEKGAAG"
     CDS             complement(15087..16289)
                     /gene_functions="transport (smcogs) SMCOG1106:major
                     facilitator transporter (Score: 116.6; E-value: 1.8e-35)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_107"
                     /transl_table=11
                     /translation="MNNADSKAARAGLGMVLILGTLASFGPLSLDMYLPALPEVAADLH
                     TTASLAQLSLTFCLLGLAVGQIVVGPLSDMIGRRKPLILSLLLYTLSSLLCAFSPSVSF
                     LIVMRFIQGFTGAAGIVIARASARDMYSGKELTAFFSLLMLVNGAAPILAPITGGFILQ
                     FAGWKIVFVVLAVIGCIISAAVLTALPESLPPEKRTSGGLRETLMTFRGLLGDRMFMGF
                     ALSQAFVMTGMFAYIAGSPFVLQNIYGVSAQMFSLLFAVNGAGIICATQITGRMAKTHD
                     ERKLFVSGLLIAVIGSIALLLSLAFGSGLTAVCISLFIIVSSVGIVTTTGFSLAMQKQE
                     KGAGSAAALLGLLPFIGGAAAAPLVGIAGEENAWPMAVSIFGFQFCAVLSYVLSAKRKT
                     K"
     CDS             16512..17750
                     /gene_functions="transport (smcogs) SMCOG1184:major
                     facilitator transporter (Score: 230.9; E-value: 3.3e-70)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_108"
                     /transl_table=11
                     /translation="MNSKQTDHIETKRRFPICLALALTLGVFAAGSEELVISPLLPDLA
                     QAFSSDVSVLALSISIYGVMIFIGAPLLVPLGDKYSRELSLLAGLLIFTAGTVICALAH
                     NLFFFFLGRALSGLAAGAFVPTAYAVVGDRVPYAYRGKVMGLIVSSWSLALIFGVPIGS
                     FIGGVLNWRWTFWIFALMSVLVASLIFIEARRSTADGDKTEEENGRQAGTFRDALKVPR
                     VPVYLTITFCNMIGFYGMYSFLGTYLHRVLPGGNTASGLLIMVYGIGFSMSVFTGKIAD
                     KAGKMRSLIAALAVISIWLSCLAYAPSSMPFLVIGLFVWGLMQSLTVTLLSTILSDCSQ
                     SRRGKIMAFYSLASNLAVTLGSAVMGPVYVGYGYAAVGFICAAVTLIGFVLSVFAYRRY
                     GKYEHQADQTLYR"
     CDS             17911..18525
                     /locus_tag="ctg8_109"
                     /transl_table=11
                     /translation="MIILDNSIQTKSKAYSISKLITINTLGPEGTSSEYAAKNFITNFT
                     LLQGVNSKLSLHDTFESCIEKTLQSPLEYTIVPHAYDGIKHFYMRPDLQLLQIFRCDTP
                     MYGLAVRPGFEYTDDMLDQTVIVSHPSPINLIKYFTRKDVTFDLVNSTSAAAKRVKDGL
                     SDIALTNELARQKYGLHFVKTFKSIPMSWSLFGKGEIHDEN"
     CDS             18512..19225
                     /locus_tag="ctg8_110"
                     /transl_table=11
                     /translation="MMKTEQDLQELYFPTPKLIEWDNGVRQYSSVRGDTEVLLSYVPPH
                     TNVEPHQHKEVQIGLVVSGELSMTVGDVTRKMTALESAYIAPPNVPHGARNETDQEVIA
                     IDIKRLKAGETYTSPEDYFLNIFKTRDLLPGMEVTFFVEDWVEIMLANIPGNGGEMPFH
                     KHRNEQIGICIGGGYDMTIEGCKVDMTFGTAYFCDPREDHGAINRFEKDSKSVNIFFPP
                     RYNRAKAKKLEAKES"
     CDS             19222..19983
                     /NRPS_PKS="Domain: PKS_KR (6-115). E-value: 4.6e-11. Score:
                     34.8. Matches aSDomain: nrpspksdomains_ctg8_111_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short_C2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     241.2; E-value: 1.9e-73)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_111"
                     /sec_met_domain="adh_short (E-value: 1.7e-36, bitscore:
                     118.8, seeds: 230, tool: rule-based-clusters)"
                     /sec_met_domain="adh_short_C2 (E-value: 1.5e-31, bitscore:
                     103.1, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLTDKTVLITGGASGIGYAAVQAFLNQEANVVVADIDEAQGEAM
                     IRKENNDRLHFVQTDITDEPACQNAIRSAADKFGGLDVLINNAGIEIVAPIHEMELSDW
                     NKVLNVNLTGMFLMSKHALKYMLKSGKGNIINTCSVGGVVAWPDIPAYNASKGGVLQLT
                     RSMAVDYAKHNIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPE
                     EIANVMLFLASDLSSYMTGSAITADGGYTAQ"
     CDS_motif       19237..19290
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_111_0001"
                     /evalue="3.60E-05"
                     /label="PKSI-ER_m5"
                     /locus_tag="ctg8_111"
                     /protein_end="23"
                     /protein_start="5"
                     /score="16.4"
                     /tool="antismash"
                     /translation="KTVLITGGASGIGYAAVQ"
     aSDomain        19240..19566
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_111_PKS_KR.1"
                     /evalue="4.60E-11"
                     /label="ctg8_111_PKS_KR.1"
                     /locus_tag="ctg8_111"
                     /protein_end="115"
                     /protein_start="6"
                     /score="34.8"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="TVLITGGASGIGYAAVQAFLNQEANVVVADIDEAQGEAMIRKENN
                     DRLHFVQTDITDEPACQNAIRSAADKFGGLDVLINNAGIEIVAPIHEMELSDWNKVLNV
                     NLTGM"
     CDS_motif       19432..19485
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg8_111_0002"
                     /evalue="2.30E+01"
                     /label="PKSI-ER_m5"
                     /locus_tag="ctg8_111"
                     /protein_end="88"
                     /protein_start="70"
                     /score="-1.8"
                     /tool="antismash"
                     /translation="IRSAADKFGGLDVLINNA"
     CDS             20001..21419
                     /gene_functions="biosynthetic (rule-based-clusters) other:
                     bacilysin"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1063:argininosuccinate lyase/adenylosuccinate lyase
                     (Score: 66.4; E-value: 4.4e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_112"
                     /sec_met_domain="bacilysin (E-value: 0.0, bitscore: 1037.8,
                     seeds: 8, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKTVLVIADLGGCPPHMFYKSAAEKYNLVSFIPRPFAITASHA
                     ALIEKYSVAVIKDKDYFKSLADFEHPDSIYWAHEDHDKPEEEVVEEIVKVAGMFAVDAI
                     TTNNELFIAPMAKACERLGLRGAGVQAAENARDKNKMRAAFNRAGVKSIKNKRVTTLED
                     FRAALQEIGTPLILKPTYLASSIGVTLIKERETAEAEFNRVNEYLKSINVPKAVTFEAP
                     FIAEEFLQGEYDDWYETSGYSDYISIEGIMADGEYFPVAIHDKTPQIGFTETSHITPSI
                     LDDDAKRKIVEAAKKANEGLGLENCATHTEIKLMKNREAGLIESAARFAGWNMIPNIKK
                     VFGVDMAQLLLDVLCFGKEADLPKGLLEQEPCYVADCHLYPQHFKENGQLPETAVDFVI
                     ESIDIPDGVLKGDTEIVSFSAAEAGTSVDLRLFEAFNSIAAFELKGSNSGDVAESIKQI
                     QQQAKLTAKYALPV"
     CDS             21416..22597
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 141.3; E-value: 7e-43)"
                     /gene_kind="transport"
                     /locus_tag="ctg8_113"
                     /transl_table=11
                     /translation="MKQLKPNSKYLLFGQALSFMGDYCVLPALLILSTYYHDYWVTSGV
                     IAVRSIPMVFQPFLGVLVDRLDRVKIMLWTDVIRGVIFLGLTFLPKGEYPLLFLALLFV
                     SYGSGVFFNPARLAVMSSLEADIKNINTLFAKATTISIIVGAAAGGLFLLGGSVELAVA
                     FNGVTYLVSAFFISRIKLQYVPIQSENVREAFQSFKEGLKEIKTNAFVLNAMFTMITMA
                     LLWGVVYSYFPIVSRFLGDGEIGNFILTFCIGFGGFIGAALVSKWGFNNNKGLMYFTVL
                     SIVSLALFLFTPIFAVSVIAAILFFIAMEYGEVLAKVKVQENAANQIQGRIFSVAEASI
                     GLCIAVGSMLINIVDAAVIMAFIVLLVSGLFLHTKLVNKSFSERNNESEQIHL"
     CDS             22610..23809
                     /NRPS_PKS="Domain: Aminotran_1_2 (32-382). E-value:
                     1.5e-77. Score: 253.0. Matches aSDomain:
                     nrpspksdomains_ctg8_114_Aminotran_1_2.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1019:aminotransferase (Score: 292.3; E-value:
                     9.1e-89)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_114"
                     /sec_met_domain="Aminotran_1_2 (E-value: 3.3e-77, bitscore:
                     253.0, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEIIPSDVIKTLPKQEFSLVFQKVKEMEKTGAQIINLGQGNPDLP
                     TPPHIVETLREAALNPSYHGYGPFRGYPFLKEAIAEFYEREYGVSVNPETEVALFGGGK
                     AGLYVLTQCLLNPGDIALVPNPGYPEYLSGITMARAELHEMPLHPENGYLPDFERIDPA
                     VLKKAKLMFLNYPNNPTGATADQAFYEKAAAFAKKHDIHLIHDFAYGAFEFDQNPASFL
                     QAKEAKTVGAELYSFSKTFNMAGWRMAFAVGNEKIIQAVNEFQDHVFVGMFGGLQQAAA
                     AALSGNPEHTERLKRTYKERIDFFTALCEKELGWSIEKPKGTFYVWAEIPNEFESSHQF
                     SDYLLEHAHVVVTPGEIFGSGGKRYVRISMVAKQGDLREFVLRIQKLGLSFPSLQETSR
                     "
     aSDomain        22706..23755
                     /aSDomain="Aminotran_1_2"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg8_114_Aminotran_1_2.1"
                     /evalue="1.50E-77"
                     /label="ctg8_114_Aminotran_1_2.1"
                     /locus_tag="ctg8_114"
                     /protein_end="382"
                     /protein_start="32"
                     /score="253.0"
                     /tool="antismash"
                     /translation="QIINLGQGNPDLPTPPHIVETLREAALNPSYHGYGPFRGYPFLKE
                     AIAEFYEREYGVSVNPETEVALFGGGKAGLYVLTQCLLNPGDIALVPNPGYPEYLSGIT
                     MARAELHEMPLHPENGYLPDFERIDPAVLKKAKLMFLNYPNNPTGATADQAFYEKAAAF
                     AKKHDIHLIHDFAYGAFEFDQNPASFLQAKEAKTVGAELYSFSKTFNMAGWRMAFAVGN
                     EKIIQAVNEFQDHVFVGMFGGLQQAAAAALSGNPEHTERLKRTYKERIDFFTALCEKEL
                     GWSIEKPKGTFYVWAEIPNEFESSHQFSDYLLEHAHVVVTPGEIFGSGGKRYVRISMVA
                     KQGDLREFVL"
     CDS             complement(23826..24626)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     165.7; E-value: 2.2e-50)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg8_115"
                     /transl_table=11
                     /translation="MVKGCRQLSKRTAFIMGASQGIGKAIALKLADNGFHTVINSRVPE
                     NIESVKEEILAKHPDAGVTVLAGDMSDQKTRAGIFEEIRSQCGRLDVLINNIPGGSPDT
                     FENCDIEDMTNTFTNKTIAYIDSMKTAAAIMKQHEFGRIINIVGNLWKEPGANMFTNSM
                     MNAALINASKNIAIQLAPFHITVNCLNPGFIATDRYHQFVKNVMKQNGISKAEAEERIA
                     SGVPMKRVGTAEETAALAAFLASEEASYITGQQVSADGGSMKSI"
     CDS             complement(24851..25225)
                     /locus_tag="ctg8_116"
                     /transl_table=11
                     /translation="MKKNFFLISFVFFIIVSGAFIALSIFTQTKLPSITFPILTLSIIS
                     FVLWATFPSLPLKRDERGKFIIQKSLAYTFMLTLIYLFIFLTIFYFNLINLDKEQILLL
                     FSSLVISTAFISILILNKKY"
     CDS             complement(25228..25425)
                     /locus_tag="ctg8_117"
                     /transl_table=11
                     /translation="MKNRLKEIRQRHSYSQETLALKLKVSRQTIISIENGKYNPSLPLA
                     LKIAKIFKESVENIFLLEEE"
     CDS             complement(25589..26353)
                     /locus_tag="ctg8_118"
                     /transl_table=11
                     /translation="MSEQQKTNEAAQTLDGWYALHDFRTMDWTSWKMLSSDERLSIIHE
                     FTGLLEKWGVAQKEGKGSQTIYSIVGQKADFMLMILRPTMEELNEIELEFNKSKLAEFT
                     IPAYSYVSVVELSNYLASGEGDPYENPHVRARLYPELPEAKYVCFYPMDKRRSGNDNWY
                     MLSMDERRNLMRSHGLIGRSYAGKVKQIITGSVGFDDYEWGVTLFSDDVLQFKKLVYEM
                     RFDEVSARYGEFGSFFVGNRLSLDTLPKFLHV"
     CDS             26615..27586
                     /locus_tag="ctg8_119"
                     /transl_table=11
                     /translation="MADLFTKVQEKVAGKDVKIVFPEGLDERILVAVNNLAGNKVLKPI
                     VVGNKEDIQAKAKELNLTLDGVDIFDPHTYEGMEELVQAFVERRKGKATEEQARKALLD
                     ENYFGTMLVYKGLADGLVSGAAHSTADTVRPALQIIKTKEGVKKTSGVFIMARGDEQYV
                     FADCAINIAPDSQDLAEIAIESANTAQMFDIDPRVAMLSFSTKGSAKSDETDKVAEAVK
                     IAKEKAPELTLDGEFQFDAAFVPSVAEKKAPDSDIKGDANVFVFPSLEAGNIGYKIAQR
                     LGGFEAVGPILQGLNMPVNDLSRGCNAEDVYNLALITAAQAL"
     CDS             complement(27623..28249)
                     /locus_tag="ctg8_120"
                     /transl_table=11
                     /translation="MTACGTAICGAAAIAAIAPQIRSNENAAAISAAAVSLLGTVFTVV
                     YSLAYHGLGFSPAAYGAFCGATLHEVAHAAAAGSAGGKAAVEMAVIVKLTRVALLVPAA
                     FMLGMRARRSGKSKTASAASLPIPWFIFGFLGMSAIHTSGVISASFSAFLVQVSYVFIG
                     MAMAGLGLKVHISAFRHNGWRALAAGLIGSLCLSLFGWAAVTFFL"
ORIGIN
        1 aaaaaagata ggagcgcaaa gaaaatggtg caaaaaagat cagcttttct tccctattca
       61 ttgcccatga tcgggaagga cgaaattcag gaggttattg atacgcttga atcgggctgg
      121 ctttcaaagg gaccgaaagt agaggcgttt gaaaaagcct ttgccgcctg gacgggggca
      181 aagcacgcga tcgcgctgaa ctcatgtacc gccgctttgt ttttggccct gaaggcgaaa
      241 gggatcggtc ccggcgacga ggtcatcact tctgccgtga cgttcagttc aacagccaat
      301 acaatcgtgc acacaggcgc cgttccggtg tttgttgaca tcgatccgct tacgctgaat
      361 gcagaccctg aaaaaattga ggcggccgtc accccgcgga caaaggcgat tgtacccgtt
      421 catttcgccg gccagtcgtg tgatatggat cagattctgg ccattgccga aaagcatcag
      481 ttatttgtct tagaggatgc cgcacatgcc gtgtacacca cttataaaca gaaaatgatc
      541 ggatcaatcg gggatgcgac ggcattcagc ttctacgcga caaaaaacct ggcaaccggt
      601 gaaggcggca tgctgacgac ggacgatgac gagcttgccg atcagatcag ggtgctcagc
      661 cttcacggca tgagcaaagg cgcgtggaac cgctattctt caaacggaag ctggtactac
      721 gaggtcgaaa cgcccggcta taaaatgaat atgtttgatc ttcaggcagc gcttgggctt
      781 catcagctga aacggattga cagcatgcag caaagaagag ccgacattgc gagccgctac
      841 caggacgcct tcagacacat gaaagggctg accatcccgc atgtcagtga tgacgggcgg
      901 catgcatggc atctgtatgt tcttcaaata gaggagcagg aggccggggt cagccggaac
      961 gatctgattt ccgctttaaa agaccaatat aatatcggca caagtgttca ttttattccg
     1021 gttccgttcc atccgtatta tcaaaaaacg tacgggtata aggaaactga ctttccggcc
     1081 gcggccgcgt attatcaccg caccgtgtca ctccctcttt atccgtcaat gacagatgac
     1141 gacgttgaat acgtcattgc agccgttacg gatatcgtca aaggggctga ttaggtgtac
     1201 agactgaggg aaaatcttgc gcaggacatg attcatacct tcctgcatca gaagggcatc
     1261 cagccggaag cctatgaatc gtcgctctgt ttattggaag aaaacagcct tcaaggcgtg
     1321 attttatatg aaaactcttc gtgggaaagt caattgttcc gaaaaaatat catcaatgtg
     1381 aagcttgcag ccgcaaacag cgccggacag ctcaaaaggc tgtttcagga attttacgtg
     1441 gcaaggcggg cggcaggcac tgattttata tttattaaaa taccggctga agatatcggc
     1501 gcgatgcagg tcgttcagca gcttccgaac gcttattttg tagggagtct gctcaagctc
     1561 gtcagtccgg tgcgtgtata taacagcacg ccgccgtttg agattacaga agccggaccc
     1621 ggcgacacgg aagcgatcag ccggctggcc cgcgacgcct ttacaaaaag caggtattac
     1681 caagaccccc atctcagcta tgaaagtgca aaccgcctgt ttgaagagtg ggcgcggaat
     1741 aatgcggaag gcagagcttc gttacaattc gccgccacat ataagggaga gactgtgggc
     1801 tttgttcagg ggctgtctaa aggcgatgaa ttcgtccttg atctgatggc ggtaaagccg
     1861 ggatttgaag gaaagggagc gggattccat ttagcggcgc acgtgattga acaatcattg
     1921 cgctttcagc ataagactgt atcagcggga acgcagctcc acaatgtaag agccatccgc
     1981 ctgtatgaaa gaatgggatt taaagcggat gcgtcctatt actactatca tgtgtggccc
     2041 gggaaggagg cggactgatg gcatcatgcc aaatcggaac gaagtcaatc ggcgaaggtt
     2101 cgcccgtatt catcatcgcc gaagccggaa ttaatcatga cggaaaactg agccaggcgt
     2161 ttgaattgat agatgcggcc agtgaggccg gcgcggacgc ggtcaagttc caaatgtttc
     2221 aggctgacaa aatgtatcag aaagaccccg gcttgtacaa aaccgctgcg ggaaaaaacg
     2281 tctctatttt ttctttggtg caatcaatgg aaatgcccgc cgagtggatc gaaccgctgc
     2341 ttgaatattg taagaaaaaa ggcgtgctgt ttttaagcac tgtctgtgat gaaggctctg
     2401 ccgacttact gtatgcgact tcgccttcag cctttaaaat cgcctcctac gagctgaacc
     2461 atctgccgtt attgaaatat gtcgcggggc tgaagacacc gattattttt tccaccgcgg
     2521 gcgctgatat ttcagatatt caggaggctt atcgaaccat taccggcgag gggaacacag
     2581 aaattgcgat catgcattgt gtggcgaaat atcccgcgcc gcctgaatac agcaatctga
     2641 gcgtcattcc catgcttgcc gccgcattcc cggatgctgt gatcggtttc tccgatcaca
     2701 gcgcccatcc gtatgatgtg ccgtgcgcgg ctgtcaggct cggagcgaaa ctgattgaaa
     2761 agcattttac gatcgataaa aacctgcccg gtgctgatca ctccttcgcc ctcaatccgg
     2821 atgaattaaa agaaatggtt gcggcgatcc gctcagttga agcggagctg cggcaggggc
     2881 atcacgctcc ggtgccggaa gtgctgtcgg gaagttccca taaaacgacg acaccgattg
     2941 aaggggatat cagaaggttc gcttacagag gcattttttc aacagcgccg attcaaaaag
     3001 gcgaatgttt tacggcggaa aaccttgccg tccttcgtcc cggccaaaaa ccgcaggggc
     3061 tccacccgag atattttgag cttttaactg acggcgcgcg tgcggtcagg gatatccccg
     3121 ccgacacggg catcacttgg gatgaccttt tgacgaaagg cagcccatat gatgactgac
     3181 attttgttta tcattcaggc gcggatggga agcgggcgtc ttcccggtaa agtgctgaaa
     3241 ccgatcggcg ggtatacgat cctcgatatg attgtcaaaa gggttcggca aagcgcgtat
     3301 tatgatcaat cgcgggataa tctgatcgtc gcctcgtctg acagcaagac cgacgacatt
     3361 ctgtctgcgc actgcatcag caagaactac cgtgtgcacc gcggcagcga gcagcgcgtg
     3421 cttgaccggt ttgcacaagt catcgaacaa gttaaaccgg acatcgcagt cagactgacg
     3481 ggggataacc cgtttgtcga cccttcgctg cttgattttc tgattcaatc gcatttagat
     3541 cagcacgcag actacacgta tatttgcggt acaccgctcg gcatcggcgg cgaggcggta
     3601 aacgcgcgcc ttttaacgga gatcaatgcc gacaaaacgc tggcggacaa ataccaggag
     3661 catgtcacgc ttttaataag agaatctcct gggaagtacc ggcttctctt tcctgagcct
     3721 ccgcaggaac tccgggctcc tcacttgcgg atgaccgtcg atacagaaga ggactacagg
     3781 ctggcccgcg agctgtacgt aaaagcgggc tcgcgtcctg atattccggc aaaagaattg
     3841 atccatctgc tgaatagtga tccggagctc agggccatta atcaaatgat ccggcaaaaa
     3901 gaggctgatt agcatgcgga ttttgatttt cgcggacggg ggccgtgaca tcggcatggg
     3961 gcacgcggtc cggatgaagc tgcttgccgg tgccattaag aacaattgct caataacgtt
     4021 ctgcacaaat aaagaggctt cttcttatct gtcttctgat caatgggaag tgatcatcaa
     4081 gcctgacaag ggacagaagg aatttattgt ccgggaaata aacaggcagg ctcctgacct
     4141 tctcatattc gatctgctcg atatgccgtg tgactggtta gaggaagtca aaaagcattc
     4201 atcggcacgc atcgtcttat ttgaagaaaa acgggaacat gtcattcatt tatgcgatgc
     4261 cgttataaac ggcatttacg gcgggctgaa aagccggacg gtccaaatgg gcagcgccgc
     4321 tgtatatgaa ggcccggaat atatgattct tcatccgggt tttgaaaaag ccaaacagct
     4381 ctatcagctg agaaaagaat gccggaccat attggtctca ttaggaggaa gcgacccgaa
     4441 gaagcttgtc tttaaagtga tggaagcatg ccgccgcatc cccgacattc atcgaaaacg
     4501 agtgatcatc gtcatgggcg gcgccgcgcc tcatgctgac gacgtgcgcg cgcatcttac
     4561 acaaatgcct tatgccgaaa tggtaaggca gacaaatgac atggccgcgc ttctttcgag
     4621 ggctgatatg gccgtcgtgt ccggcgggat cactttatat gaaaccattt gtacaggtgt
     4681 gccctgcatc gtactttctc aagtggagca tcaaactgag acggcggaaa aattcgccgc
     4741 acggggggcc gccgttcatc tcggccttgg tgaatgcata tcaccggacg ttctcgcacg
     4801 gcatatgtct gacatggccg ctgattatcc gctgcggacc ggacttcatc aaaacggaaa
     4861 gccgctggtt gacggcaggg gcatcaaacg ggcggcggcg attctttatg atttgtgata
     4921 aaaccacacg taaggaagtg ttcatgtgaa aggtgttatc ttagccggag gcaccggctc
     4981 acgccttatg ccgctgacaa aagcggtcaa taagcattta ctccctgtcg gtccatatcc
     5041 gatgatttac tggtcgatca tgaagctgga agaagcgggg attacagata tcctgctgat
     5101 tacgcaaaaa gaatatattc cgcaatttca taaacttctc gaaaccggag aagagctcgg
     5161 cgtctcaatc acatatcagg ttcagccagc cgcatccggt atttccgacg gtttatcata
     5221 cgcaaagcga tttacaggtc gcgatccgtt cgttctgctt ttgggagata atatttttga
     5281 agattcatta aaaccttata cggagcgttt cgcaaagcag ggaaaaggag cgaaagtgct
     5341 gctgaaagaa gtggacgatc cggagcgctt cggcatcgcc gagattgatg aggaaaacaa
     5401 acggatcaag tcgatcattg aaaagccgga gcagccgccg accagactat gcgtcacagg
     5461 gatctacatg tacgacgcag aagtgttttc ctatattgaa caaatttccc cttcaaaacg
     5521 cggcgaactg gaaattacgg atgtcaataa tttatacatt gaacacagtg agctgacgta
     5581 tgatgtgtta acgggctggt gggtggatgc gggtacgcat gaatcgctct acctcgccgg
     5641 aagcctggcg catcaggcat tacagaaagg acaggagcat taatcatgcc aaaatcatat
     5701 ttaattacag ggggcgccgg atttatcggc cttaccttta caaagatgat gctgaaagaa
     5761 acggacgcgc agattaccgt cctggataat ctcacgtatg caagcaggcc gcttgaaata
     5821 gaagccttga aaaagaacgg ccgtttccgt tttatcaaag gtgacatttc ggaaaaagag
     5881 gacattgaca aagttttttc ccaaatgtat gacgctgtca ttcattttgc ggctgaatcc
     5941 catgtggaca gaagcataaa tcaggcagag ccgttcatca caacaaatgt aatgggcaca
     6001 taccgactgg cggacgcggt gttacaggga aaagccggca ggctgattca catttccaca
     6061 gatgaggtgt acggagattt ggcgccggat gatcccgctt ttacggagac gacgccgctt
     6121 tctccgaaca atccgtattc ggccagcaag gcaagctcag acctgctcgt catgtcttac
     6181 gtgagaaccc ataagcttcc tgccatcatt acaagatgca gcaacaatta cgggccgtac
     6241 cagcatcacg agaaaatgat tccgaccatt atcaggcatg ccgtaaacgg cacgccggtt
     6301 ccgctgtacg gcgacgggat gcagatcaga gactggctgt ttgccgaaga tcattgccgc
     6361 gccattaagc tcgtgctgga aaaaggaaca ctcggtgcca tttacaatat cggcggagga
     6421 aatgaacgga cgaataaaga gcttgcgtca tttatcatga aggagctcgg tgtcgaggaa
     6481 cggtttgctc atgtcgaaga cagaaaaggg catgaccgcc gttacgccat caatgcttca
     6541 aagctgaaaa atgagctggg atggcggcag gacgtcacat ttgaagaagg aatgagaaga
     6601 accattcgct ggtatacaga cagccaagac taatcggaaa gaaggggatc cgattgacga
     6661 aggtattagt aaccggagcg gccggccagc tggggcggga gttatgccgt cagctgaagc
     6721 gggaagggta tgaagtgatc gccttgacaa aagcgatgat gaacatatcc gaccagcgtt
     6781 cggtgcggca ctcgttcagc cattacaagc cggatatcgt cgtcaatacg gcggcataca
     6841 cctctgttga caaatgtgaa acggagctcg acaaagcgta tttaataaac ggaatcggcg
     6901 cttattatgc cgcgcttgag gctgaaaaca ccggcgcgaa attcattcac atcagcaccg
     6961 attacgtctt cagcggcaaa ggaacacggc cataccagac cgatgatccc gcagatccgg
     7021 gcacgattta tggaaaaagc aaaaaactcg gcgaagaact gatccggtta acggggaaaa
     7081 accacaccat tatcagaaca tcgtgggtgt acggcagcgg cgggcacaac tttgtcaata
     7141 cgatgctgaa acttgcggat acacataatc aggtgcgtgt cgttaacgat caagtcgggg
     7201 cgccgacgta cacaaaagat ttagccgaaa cggtgatcgg tctgtttgac aggccgccgg
     7261 gcttatacca cgccgcaaac agcggagtgt gcagctggta tgaatttgcc aaggctattt
     7321 ttgaagaaag cggcagaacc gccgccgtgc tgcccgtcac gacggaggaa tacggaaatg
     7381 agacgccgcg ccccgcttac tcggtgttga gtcttgagtc gattgaacgg caggggctcg
     7441 ggatgaggca ttggcgggaa gcgctgcatg attatttaca aagggaggga cagtgcaagt
     7501 gatcgaaggc gtaaaaatca aaaagctgat caaacacagc gatgaccggg gttttttctc
     7561 agaactcgtc cgtgacgatg aacatctctt agagcgtttc gggcaggctt cctggtccaa
     7621 aagctatccc ggcgtcatta aagcgtttca ctatcatgag aaacaggatg acctatggtt
     7681 ttttccgacg ggccacgccc aggtcgtgct gcatgacctt cgcgaagagt cggcaaccaa
     7741 gggagaaacg gatgtctact acatgggaga agacaatccg atgctccttc tcattcccaa
     7801 aggcgtcgca cacgggtaca gagtgctggg cgaaaccccg ctgaccatta tttatttcac
     7861 gacaatgtcc tacaatccgg atcagcctga cgaaaaaaga attccgtgga atgatgacac
     7921 catcggattt gactggcaga cggctcaccg atagcgcaaa agacgaagac agcggatgtc
     7981 ttcgtttttt gtgctgattc atctcgtgaa aaaaatgatt gaatattcca aaaaataatt
     8041 tacttccatg gataaaggtg gtagattatt ctcaggaaaa gagaaaccca attcgcgaat
     8101 ggaaccatca gacacgcttt tccggcagag gacgctctga atcccatatg atctggagga
     8161 attcatgatg ttaaaaagaa aatcattttc ggcctttctc atcagtgctg cggtattttc
     8221 atctgtgttc ttgccatctt ttcatgcgaa cgcccaatct gccgttattg aagcgaaaac
     8281 cgtcaatagt acgaaagaat acgcgacgtc tgatattgaa gtcacataca agccgaatgc
     8341 gctgcttgcc gtcggcgccg ttgaatttca atttcctgcc gggttcaacg ccactgtgag
     8401 ggactctgta aacggaagaa cactgaaaga aacgcaaatt ctcaactacg gaaaaacggt
     8461 cagacttccg cttacccttg acttattggg cgcgtctgaa tacaatctcg tcctagtgcg
     8521 taaaaacctt ccgcgcgcgg gcgcgtatac aattaaaggc gattacgtaa acggtttggg
     8581 ggccggcagt ctttatgccg aaacaaagct ggttattgac ccgcgttaat cggggatgaa
     8641 agaggctgac aacagcctct tttttttata agcaaaaacc tggcatgaat cttgcatata
     8701 aaaaggggcg taacgacaat gtgaaaggga ttgatgggtt ttggtgtaaa agcgcttaca
     8761 ttttgttctg ccggtaattg aagcttacac gtaaaatacg atgaggtgat aaaacatgtc
     8821 agccaacccg atttctaaaa gcaatcagaa agatgaagaa aaagaagttc ttaatttgtt
     8881 cttgtcaaca caatcgatca taaaagaggc cctgcgaaaa ctggggtacc ctgacaatat
     8941 gtatgaactg atgaaagagc cgatgcggct tttgaccgtc cgcatccctg tcaaaatgga
     9001 caatggctca gtacaggttt tcacgggcta ccgctcacag cataatgacg cagtcggccc
     9061 gacaaaaggg ggcgtgcggt ttcatccgga agtcagtgaa gaagaggtta aggcgctttc
     9121 catctggatg actttaaaat gcggcatcac aaatcttcct tacgggggcg gaaaaggcgg
     9181 catcatctgt gatcctcgga cgatgtcatt cggagagctg gaacggctga gccgcggata
     9241 tgtgcgtgcg atcagccaga tcgtcggtcc gacaaaggat attccggctc ccgacgtata
     9301 taccaactcg cagattatgg catggatgat ggacgaatac agccgcctga gagaatttga
     9361 ttcaccggga ttcattacgg gcaaaccgat tgttctcggc ggttcacagg ggcgggaaac
     9421 ggcgaccgcg caaggcgtca cgatttgtat tgaggaagcc gttaagaaaa aagggattcc
     9481 attggaaaat gcgcggatca tcattcaggg gttcggaaat gcggggagct ttctcgctaa
     9541 atttatgcat gacgccggcg ccaaggtgat cggcatctca gacgcccacg gcgctttgta
     9601 tgaccctgac ggccttgaca ttgattacct gctggataag cgggacagct tcggcacggt
     9661 gacgaatctc ttctcggatg tcataacgaa cagggagctg ctggaaaagg actgtgatat
     9721 tctcgtgccc gccgcaatct ccaatcagat tacggctgaa aacgcccatc acattaaagc
     9781 ctcaatcatt gtggaggcgg caaacggccc gacaacgata gatgccacga aaattctgaa
     9841 tgaaagaggc gtgcttctcg tgccggatat tttggcaagc gccggcggcg tgacggtgtc
     9901 ttattttgaa tgggtgcaaa ataatcaagg cttttactgg tctgaggagg aagttgccgg
     9961 aaaactgcgc agcgtcatgg tgaattcgtt tgaatccatt tatcagacag cgcataccca
    10021 caaagtcgat atgcgtttgg ccgcctatat gacgggcatc agaaagtcgg ctgaagcggc
    10081 ccgtttccgc ggctgggtat aagtgttatc cgcaaagaga ttttgcatca gttatatagc
    10141 agatcgcaaa atttctttgc gttttcagat tgcagctgac agattcggac aagcttcgtc
    10201 cgctttcggc aaagattttc ttatttttat cacaaattgc tatgctggta tgcttcttgc
    10261 atcttcataa tgcgtgagca cacattacaa aatacgggga ggaattctaa tgacagtttc
    10321 atacgcacac gaaccattta caaattttca ggaagagaca aataaacaat cgtttcagga
    10381 agcgctggct tatgtaaatt cacagctcgg caagcattat ccgcttatca tcaacggtga
    10441 agcgattgaa acggataaaa agatcatttc cgtcaatccg gcagataaaa aagaagtgat
    10501 cggttctgta tcggcagccg gaaaagaact tgcggaaaag gccatgcagg ctgcactgca
    10561 ggcatttcaa acatggaaaa aagcacggcc ggaacaccgc gcgaatgtgc tgtttaaagc
    10621 ggcggcgatc atccgcagaa gaaagcacga attctccgca tatctagtga aagaagcggg
    10681 aaaaccgtgg aaggaagcgg atgcggatac ggcggaagcg atcgactttt tagagtatta
    10741 cgcccgtcag atgctgaaac tgaaagacgg ttcccctgta aagagccgtg acggagaata
    10801 taatcagtat cactatgagc cgcttggggt gggaatcgtc atttctccat tcaacttccc
    10861 gcttgcgatc atggcgggaa cggcggcggc agccatcgta acaggcaaca cgatactgct
    10921 gaaaccggcg gatgcggcgc ctgtcgtggc ggcgaaattc gttgacgtga tgaaagaagc
    10981 gggcctgccg gacggcgtgc ttcaattcat accgggcgac ggaggagaaa tcggcgacta
    11041 tctggttgag catccgaaga cgagatttgt gtcgtttaca ggttcccgcg cggtcggatg
    11101 ccgcatttat gaacgcgccg caaaagtaca gccgggccaa aagtggctga aacgggtcat
    11161 tgccgaaatg ggagggaaag atacggtgct tgtagacaga gatgctgatc ttgatcttgc
    11221 cgcttcctca atcgtgtatt ccgccttcgg attctcaggc caaaaatgtt cagccggttc
    11281 ccgtgcggtc atccatcagg acgtctatga tgaagttgtt gaaaaagccg tcgctttaac
    11341 aaaatcactc accgtcggaa gtccggaaga ttttgataca tacatggggc cagttatcca
    11401 cgaagcatct tataataaag tcatgaatta tatcgaaatc ggcaaaacag aaggaaaact
    11461 cctgacggga ggcgaaggtg atgattcaaa aggatacttt attcagccga ccatttttgc
    11521 ggatgttgat gaaaacgccc gcctgatgca ggaggaaatt ttcgggccgg tcgtcgcgat
    11581 ctcaaaagcc cgtgatttcg accatatgct tgagattgcc aataataccg attacggact
    11641 gacgggcgct ctgttatcga aaacccgtgc gcacattgaa cgcgcccgcg aagattttca
    11701 cgtcgggaat ctatacttca accgcggatg tacgggagcg attgtcggat accagccgtt
    11761 cggcggcttc aatatgtcag gaaccgattc aaaagccgga ggacctgact atctgattct
    11821 tcatatgcag gcaaaaacaa cgtctgaagc ctattaatct ttcggaaata gcgcgatgaa
    11881 aaagagagtc gcgctatttt ctctatatga aggtaaggag gatggaacat gtatcagcag
    11941 ctcagcaaaa tgcttccgga ggagaaaata gaagccatta cgaaatcact ggtggcgtta
    12001 aacagcatca acggcacatt gggagaagga aaaaaagccg actatatcaa agatatgatc
    12061 aagagctttc cctactttca ggagaatccg tcacatgtgt gggagcaggc gattcctgag
    12121 gacccttacg gccgcaaaaa tattttcgca tttattgagg gaaacggcga aagcctgaat
    12181 acggtcattt atcacgctca tcttgatacg gtcggcatcg aggatttcgg ccctttaaaa
    12241 gatatcgctt ttgattccga ccgtctcgcg gaatatttct caaactatga atttgatcgg
    12301 gatgtgcagc gggacgcccg ctcaggcgag tggatgttcg gaaggggttc ggttgatatg
    12361 cagagcggta ttgccgttca tctcgccaat ctgcttcact tttctgaacg gcgcgatcag
    12421 ctgccgggcc atattctgtt catggcaaat ccggatgaag aaagccagca ttccggcatt
    12481 ttaaccagca tttctgaatt aaaacggctg aaacaagaaa agcagcttcg ttatttagca
    12541 gcgattaata acgattttat cacgccgctg tatgagggtg acacgacaag gtacatctac
    12601 acgggcgcgg cagggaagct tttgccttgc tttgcgattt acgggcggga ggtgcatgtc
    12661 ggtgatacgc tgtccggcat cgatccgaat ttgatcgcat cagaaatcac cagaagaatt
    12721 cacaacaata ttcatatggc ggaaaacatt gaaggggagc ttgtgcttcc gccgacctgc
    12781 ctgtaccagc gtgacaataa ggaagcgtat aacgtgcaga ccgccgtcag cagctatgtc
    12841 tattttaatt attttattta cgagaaaacc gccaaagtag tcatggatca gctgactgcc
    12901 gtggctgacg aagcctgcaa agagacagaa cgaaaattat ctgattatta cgacgaatac
    12961 tgtgagagaa cgagcctgcc gaaaaaagag atgtcatgga acgttcaagt gtacagtctg
    13021 gaagattacc tgaaaaggct tagaagccgc gggatagacc ctgcacagtg tatcgagcag
    13081 gcatttaaaa catatgaaca tcttgaactg cggatgagat gctttaaagc cgtcgaggaa
    13141 ctgcaaaaac tcgatcctga gcagggagcc aaggtcatta ttttctatgc gccgccttac
    13201 cttccgcaca attatctgaa agaagagagc tcacgggacc ggcttttgca gcatgtcatt
    13261 caagaagcgg tcgataaaac agcggcatca accggagaaa cattcgtctt taaaaagttt
    13321 ttcccttatt tagcggacgg aagcttttta tcgctgcatg aaacagacga ggaggtctcc
    13381 gcctttaccg ataattttcc gggctgggat gtcatcggga cgattccttt taaagaaatc
    13441 agggaattga atattccgtc ggtcaatata ggggtatacg gaaaggacgg ccataaatgg
    13501 acggaacgcg tgtacaagcc gtacacattc catgtgctgc cggagctcat tcagcagacg
    13561 acaatgcacc ttttgcacag ctaccgatta gacatacgca caaatggctg acataacgga
    13621 ataaggagga tgtatatgca gggagatacc aatcaaactg aattgcagcg cacgatgaag
    13681 ggccggcatt tgtttatgat cgccctcggc ggcgtgatcg ggacggggct ttttctgggc
    13741 tccggtttta cgatcagtga agcgggaccg atcggcgcga tattggctta tgtgatcggc
    13801 ggatttttaa tgtatctggt gatgctttgt ttgggggagc tcgcggtcgc catgccggtc
    13861 gcaggatcat ttcaagcgta tgccgcaaag tttctcgggc cgtcgacggg ttttacgatc
    13921 ggatggatgt acgcattcag ctgggccaat acagtggggc ttgaactgac gtcggcgggg
    13981 attttaatgc agcggtggtt tccggccgtt ccgatttggg tgtggtgcct tgtattcggc
    14041 gtcgtcattt tttccattaa cgcgctgtct gcgcggagtt ttgcggaaat ggaattttgg
    14101 ttttccagca ttaaggtcat ggccattgta ttgtttatta ttctcggctg cgctgcggta
    14161 ttcggctttg tcggttttaa cggcgggcag acggctccgt atctgtcaaa ctttacgacg
    14221 gacaaagggc ttttcccgaa cggtgcccaa gccgtgctat ttacccttgt catggtgaat
    14281 ttttcattcc agggcaccga gctggtcgga atcgcctcgg gagaaagcga aaatccggaa
    14341 aagacgcttc cccgctcaat tcgaaacgtc atatggcgga cgctgttttt cttcgtgctg
    14401 gcgatgtttg ttctcgtgtc cattttgccg taccaaacgg caggcgtcat cgaaagcccg
    14461 tttgtggctg tgctggataa aatcggcgtt ccctatgcgg ctgatatcat gaactttgtc
    14521 attctgaccg ccatgctgtc ggtggcgaat tccgggctgt acgcttcgtc cagaatgatg
    14581 tggtccctat caaaaactaa gatgggcccc gcttccttaa cgaaactgac gaaaaaaggc
    14641 gtgcctctga aagctctttc catcaccatc gccatctccg gtttatccct gctgacaagt
    14701 gtattcgcgg ctgaaacggt gtatgtgtgg ctcatttcca tctccggtat gattaccgtc
    14761 gtcgcgtgga tgtcaatctg cgcttcacaa ttcgttttcc gaagacgctt tctcgctgaa
    14821 ggaggaaatc tgaaagacct ggcatttaaa acgcctcttt atccgatcgt gccgattctc
    14881 ggattttcgg tttacggtct tatcttaatc agtctcatct ttatccccga ccagcgtatc
    14941 ggtctgtact gcggcgtccc gctgatgatc atttgttacg cgtattatca cttcggtatc
    15001 aaaaaacgcc tgaagcgtga gccggcttct tcggaaaaag gcgctgccgg ataagaaaaa
    15061 aagccctccg caaaaagcgg cgggctttac tttgttttcc gttttgccga cagcacatag
    15121 gatagaacgg cacagaactg aaaaccgaaa atgctgacgg ccatcggcca ggcattttct
    15181 tctccggcaa taccgaccag gggagcggca gccgcaccgc cgataaaggg caggagtccg
    15241 agaagagctg cagcgcttcc cgcgcctttc tcctgtttct gcatagccag agaaaatccc
    15301 gtcgtcgtga cgatcccgac agaagaaaca atgatgaata atgaaatgca gaccgccgtc
    15361 aggcctgaac caaacgcaag tgataaaagc aaagcgatgc ttccgatgac ggcgatcaac
    15421 agcccggaga caaacagctt ccgttcatca tgtgttttgg ccatccgtcc ggtgatttga
    15481 gtggcgcata tgattcccgc accgtttacg gcgaacagca ggctgaacat ttgcgccgat
    15541 acgccgtaga tgttttgcag tacaaacggc gatccggcaa tatatgcgaa catgccggtc
    15601 atcacaaatg cctggctgag cgcaaatccc ataaacatcc ggtcgccaag caggccgcga
    15661 aacgtcatca gcgtctcccg gagtccgccg cttgtccgct tttccggcgg gagtgattca
    15721 ggcaacgccg taagcacggc ggcggaaatg atacagccga tcaccgccag cacgacaaat
    15781 acgattttcc agccggcgaa ctgaaggata aatccccctg taatcggcgc taaaatcggt
    15841 gccgccccat tgacgagcat cagtaatgag aaaaaagccg tcaattcttt tccggaatac
    15901 atatcgcgtg cggacgcccg tgcgatgacg attccggccg ccccggtgaa tccttgaata
    15961 aacctcatga caattaaaaa cgaaacagaa gggctgaagg cgcataataa agaagacagc
    16021 gtataaagca gcaatgacag aatgagcggc ttccggcgcc cgatcatatc actgagcggc
    16081 ccgacaacga tctgcccgac cgccagcccc aaaagacaaa acgtcaggct cagctgcgca
    16141 agtgacgctg tcgtatgaag atcggccgcc acctcaggca aagcgggcag atacatatcg
    16201 agcgaaagcg gcccgaatga agcgagcgtc ccgagaatca gtaccatgcc gaggcctgcg
    16261 cgggcggcct ttgaatcagc gttattcatt ccatgacccc caccttaaca aatgattcta
    16321 tcactatagc ataaccggac ggcgtatttt atatcattta ttgaatacaa actaaatatt
    16381 ttatttaaaa tctgaatgta aataaaaaat tggaattagt tttcatgtga aatgtaaaat
    16441 gaaacataag gatgctaaac tataaaacaa caaaaggtag aaaagtttta cggaagaggt
    16501 gttcaaagag catgaacagc aaacaaaccg atcacatcga aacgaaacgc cgatttccga
    16561 tctgtctcgc gcttgctttg acattaggcg tatttgccgc cggttctgaa gagctggtga
    16621 tttctccgct gcttccggat ttagcgcagg ctttcagctc ggatgtcagt gtgctggcgc
    16681 tttccatcag tatttacgga gtgatgattt ttatcggcgc gccgcttctc gttccgctgg
    16741 gagataaata ttcccgggag ctcagcctgc tggcggggct gcttatattt acggccggca
    16801 cggtgatctg cgcgctggcg cacaatctct ttttcttctt tctgggcagg gcgctttcag
    16861 ggctcgcggc gggtgcgttt gtgccgacag catatgcggt ggtcggcgac cgtgtgcctt
    16921 atgcgtaccg cggcaaggtg atgggtctga tcgtgtcaag ctggtcgctc gctttgattt
    16981 tcggtgttcc gatcggctct tttatcggcg gcgttttaaa ttggcggtgg acgttttgga
    17041 ttttcgccct catgtctgtc ctcgttgctt cgctcatttt cattgaggcg cgccgcagca
    17101 cggcggatgg ggataaaaca gaagaggaaa acggacggca ggcaggcact ttccgggatg
    17161 cgctgaaggt gccccgtgtc cctgtatacc tcacgatcac tttttgcaac atgatcggtt
    17221 tttacggcat gtattccttt ctcggcacat atcttcaccg cgtgctgccg gggggaaata
    17281 cagcttcagg gctgctgatc atggtgtacg gaatcggttt ttccatgagc gtgttcaccg
    17341 gaaaaatcgc agataaggcg gggaaaatgc gctctttgat cgcggcattg gccgtgatca
    17401 gcatatggct ttcctgtctc gcctatgcgc cgtcatcaat gccgtttttg gtcatcgggt
    17461 tattcgtctg gggattgatg caaagcctga cggtgacctt gctcagcacc attttaagtg
    17521 attgctcaca gagccgccgg ggcaaaatca tggcatttta cagcctggcg tccaatttgg
    17581 ccgtcacctt gggttctgct gtcatgggtc cggtctatgt cggatacgga tatgcagctg
    17641 tcggatttat ttgtgcggcc gtcaccctca tcggctttgt cctcagcgtt ttcgcataca
    17701 gaagatatgg gaaatatgag catcaggccg accaaacatt gtatcggtaa aataaagttt
    17761 ctataatttt ataaatgtta attttaacac cctatgtcat agggtgtttt ctaatatata
    17821 gggataatta tcaatatttt caaataatat tgacagcttg aacatctatg gataatattt
    17881 acttaaaatt taacagattg gttggtgctc atgattatat tggataatag cattcaaacg
    17941 aaaagcaagg cttattcaat atctaaactg attacgatca acacgctcgg tcctgaaggg
    18001 acaagcagtg agtacgcagc aaaaaacttc attaccaatt tcacccttct ccaaggggtg
    18061 aacagcaaat tatcactgca tgatacattt gaatcgtgca ttgaaaaaac gcttcaaagt
    18121 ccgctggaat acacaattgt gcctcacgcg tatgacggca ttaagcactt ctacatgaga
    18181 ccggatctgc agcttctgca aattttcagg tgcgacaccc cgatgtacgg cctggctgtc
    18241 cggcccggtt ttgaatatac ggatgacatg cttgatcaga ctgtcatcgt atcccacccg
    18301 tctcctatca atttgattaa gtattttacc cgtaaagatg tcacgtttga tctggtgaac
    18361 tcaacgagcg cagccgcgaa aagagtgaag gacggtttgt ccgacatcgc gctgacaaat
    18421 gagctggcca gacaaaagta cggtcttcac tttgtcaaaa catttaaaag cattcccatg
    18481 agctggtcat tattcggaaa aggagagatt catgatgaaa actgaacaag atttgcagga
    18541 actttatttc ccgacgccta aattaataga atgggataac ggagtaagac aatattcgtc
    18601 cgtcagagga gatacggaag ttctgctttc ttacgttccg ccgcatacaa acgtggaacc
    18661 gcatcagcat aaggaagtcc aaatcggcct tgtcgtttcc ggggagctgt ccatgactgt
    18721 cggagatgtc acaagaaaga tgacagcgct ggaatcagcc tatatcgcgc ctcctaatgt
    18781 gcctcacggc gcaagaaatg agacggatca agaagtgatc gccattgata ttaaacgcct
    18841 gaaagccggt gaaacctaca caagccctga agattatttt ttgaatattt ttaaaacgag
    18901 agacttattg cccggtatgg aagtcacgtt cttcgtggaa gactgggtgg aaatcatgct
    18961 tgccaacatt ccgggcaacg ggggagaaat gccgttccat aaacaccgca atgaacagat
    19021 cggcatctgc atcggcggcg gctatgatat gaccattgaa ggctgcaaag tggatatgac
    19081 attcggcaca gcttatttct gcgatccgag agaagatcac ggcgccatca acagatttga
    19141 aaaagattca aaatcagtca atatcttttt ccctccgcgc tataacagag caaaagcgaa
    19201 aaaattagag gcgaaagagt catgaacctg acggataaaa ccgtcctcat cacagggggc
    19261 gcatcaggca tcggttatgc cgcggttcag gcgtttctga atcaagaggc gaatgtggtc
    19321 gtcgcggata ttgatgaggc gcagggagaa gcgatgatca ggaaagaaaa caatgacagg
    19381 ctgcattttg tgcagacgga tattacagat gagccggcat gtcaaaacgc catccggtca
    19441 gcggcggaca agttcggcgg attggacgtg ttaatcaata acgccggcat cgaaattgtc
    19501 gccccgattc atgagatgga gctgagcgat tggaacaagg tgctcaacgt caatctgacg
    19561 ggcatgtttc ttatgagcaa gcacgcgctc aagtatatgc tcaaaagcgg caagggcaat
    19621 atcattaaca cgtgctccgt cggaggagtc gttgcatggc ccgacattcc cgcatataac
    19681 gcctctaaag gcggcgtatt gcagctgacg cgttcgatgg ctgttgatta cgccaaacac
    19741 aacatccgcg tcaattgcgt gtgcccggga atcattgaca cacctttgaa tgaaaagtcg
    19801 ttccttgaaa acaacgaagg cacgcttgaa gaaatcaaaa aagaaaaagc gaaagtcaat
    19861 ccgctgctga gactcggcaa gcctgaagaa atagcgaacg tcatgctgtt tctcgcgtcg
    19921 gatttatcaa gctatatgac cggaagcgcg atcaccgcag acggtggata caccgcacaa
    19981 tagagaagga gtgtttacat atggagagaa aaacagtatt ggttatcgct gaccttgggg
    20041 gatgcccgcc gcatatgttt tacaaaagcg cagccgaaaa atacaacctc gtcagcttta
    20101 ttccgagacc ttttgcaatt acagcctctc atgcggcatt aattgaaaaa tactcggtcg
    20161 cggtcataaa agataaagac tattttaaga gtctggctga ttttgagcat cccgattcga
    20221 tttactgggc tcatgaagat catgacaaac ctgaggaaga agtagtcgaa gaaatcgtca
    20281 aggtggccgg catgttcgcg gttgacgcca ttacgaccaa caatgaactg tttatcgctc
    20341 cgatggcaaa agcgtgtgaa cgtctcggcc tgcggggagc gggcgtacag gccgctgaaa
    20401 atgccagaga taaaaacaaa atgagagccg ctttcaaccg ggccggcgtc aagtctatca
    20461 aaaacaaacg ggtgacgacg ctggaagatt tccgcgccgc gcttcaggaa atcggaacgc
    20521 cgctcattct gaagcctaca tatctggcga gctccatcgg cgtgacgctt atcaaagaga
    20581 gggaaacggc cgaagccgaa tttaacagag tcaatgaata cctgaagtcg atcaacgtac
    20641 cgaaagcggt cacgtttgaa gcgccgttta tcgcggaaga atttttgcag ggcgagtatg
    20701 acgactggta cgaaacaagc ggttattccg actatatcag catagagggc atcatggccg
    20761 acggagaata cttccctgtc gcaattcatg ataaaacacc gcaaatcgga ttcacggaga
    20821 catcgcatat tacgccgtcc atcctggatg atgacgcgaa gcggaaaatc gtcgaagcag
    20881 ccaaaaaggc gaatgaagga ctcggcctcg aaaactgcgc aacccataca gagattaaat
    20941 taatgaaaaa ccgggaagcc ggactgattg aatcagcggc acgatttgcg ggctggaaca
    21001 tgattccgaa tattaaaaag gtcttcggcg tcgatatggc gcagctgtta ttggatgttc
    21061 tctgtttcgg aaaagaagcc gatctgccga aaggattatt ggagcaggag ccatgctatg
    21121 tcgccgactg ccacttgtat cctcagcatt tcaaagaaaa cggccagctg cctgagacgg
    21181 ctgtcgattt cgtcattgaa agcattgaca ttcccgacgg cgtcttaaag ggagacaccg
    21241 aaatcgtttc tttctcggcg gccgaggcgg gtacatccgt ggatctgcgg ctgttcgaag
    21301 cgttcaacag cattgcggcg ttcgagctga aaggaagcaa ttcgggtgac gtggccgaat
    21361 caatcaaaca aattcagcag caggcgaagc tgactgcaaa gtatgcgtta ccggtatgaa
    21421 acagctgaaa ccgaactcta agtatttgct tttcgggcag gcgctttcgt ttatgggaga
    21481 ctattgcgtt ctcccggctc tgctcatttt gtctacatac tatcacgact actgggtgac
    21541 gtccggcgtc atcgcggtcc gcagtattcc gatggtgttt cagccgtttt taggcgtgct
    21601 cgtggaccgg ctcgacaggg tgaaaatcat gctgtggacg gatgtgatca gaggcgtcat
    21661 ctttttgggg ctgacatttc tcccgaaagg cgaatatccg ctgctttttc tggcgctgct
    21721 gtttgtttct tacggaagcg gcgtgttttt taacccggca cgtctcgcgg tcatgtcgtc
    21781 tttagaagcg gatattaaaa atatcaacac tttgtttgca aaagccacga cgatttcgat
    21841 tattgtcggc gctgcagccg gcggactttt tctgttaggc ggttctgtgg agcttgccgt
    21901 cgcctttaac ggggtgacct atcttgtctc cgcgtttttc atcagccgca ttaagcttca
    21961 atacgtgccg attcagtcag aaaacgtgag agaagctttt cagtcgttta aagaaggcct
    22021 gaaggaaatc aaaacaaatg cttttgtgtt aaatgccatg ttcacgatga ttacgatggc
    22081 gcttttgtgg ggtgtcgtct acagctattt cccgattgtc agccgctttt taggcgacgg
    22141 ggaaatcggc aatttcatcc tgacgttctg tatcggcttc ggcggcttta tcggtgccgc
    22201 tcttgtcagc aaatggggct ttaacaacaa taaagggctg atgtatttta cagtgttatc
    22261 gatcgtctcg cttgcgctgt ttttgtttac cccgattttc gccgtgtcag tcattgccgc
    22321 cattcttttc tttatcgcaa tggaatacgg tgaggtgctg gcgaaggtca aagttcagga
    22381 gaacgcggcg aaccagattc agggccggat tttttcggtg gcggaggcct ccatcggatt
    22441 gtgcatcgcc gtcggttcca tgctgatcaa cattgtagac gcggcagtca tcatggcgtt
    22501 tatcgtcctt ttggtcagcg ggctgtttct gcatacaaaa ctggtcaata aatccttttc
    22561 agaacggaat aacgaatcag agcaaattca tttataagga gcctttcaga tggaaatcat
    22621 accgtccgac gtcatcaaga cacttccgaa acaggaattt tcgctcgttt ttcaaaaggt
    22681 aaaagagatg gagaaaacgg gagcccagat cattaatctc gggcagggga atcccgatct
    22741 ccccacaccg ccgcatatcg ttgaaacatt gcgggaggct gcgctgaatc cttcgtatca
    22801 cggatacggc ccgttcagag gctatccgtt tctgaaagaa gccatcgcgg aattttatga
    22861 gagagagtac ggggtatcgg tcaatccgga gacagaagtc gcgctgttcg gcggagggaa
    22921 agctggtttg tacgttttga cgcaatgcct gctgaatccc ggcgatatcg ccttagtccc
    22981 gaaccccggc taccctgagt atttatcggg cattacaatg gccagagcgg agctgcatga
    23041 gatgccgctt catccggaaa acggctattt gccggatttt gagcggattg atcccgccgt
    23101 cctgaaaaaa gccaagctga tgtttttgaa ttacccgaat aacccgacgg gcgcgactgc
    23161 ggatcaggcg ttttatgaaa aagcggcagc gtttgcaaaa aaacatgaca tccaccttat
    23221 tcacgatttt gcatacggcg cgttcgaatt tgatcagaac ccggccagct ttcttcaggc
    23281 gaaagaagcg aaaacggtcg gcgcggagct ttattcattt tcgaaaacct tcaatatggc
    23341 aggctggaga atggcatttg ccgtggggaa tgagaaaatc attcaggcgg tcaatgagtt
    23401 tcaggatcac gtcttcgtcg gcatgttcgg cggtcttcag caggcggcag cggcggcgct
    23461 gtcaggaaat cctgagcata cggagcgtct gaagcgcaca tataaagaac ggattgactt
    23521 tttcacggcg ttatgtgaaa aggaattagg ctggagcatt gaaaaaccga aagggacttt
    23581 ttatgtatgg gctgaaattc cgaatgaatt cgagtcttca caccagtttt cggactattt
    23641 gctggagcat gcccatgttg tcgtgacgcc cggcgagatt ttcggcagcg gcggaaagcg
    23701 ttatgtcaga atatcaatgg tggccaagca gggcgattta agggaattcg tgctgcggat
    23761 tcaaaagctc ggtttgtcct ttccttcatt acaagaaaca tcccgctgag agcgggatgt
    23821 ttttattata tgcttttcat gctgccgccg tcggctgata cttgctgtcc ggtaatatag
    23881 gaggcttctt cagaggcaag aaaggcagcc agcgccgcgg tttcttccgc agttccgaca
    23941 cgcttcatcg ggacgcctga ggcaatccgt tcttccgctt ccgctttaga aatgccgttt
    24001 tgcttcatga cattcttcac gaattggtga taacggtctg tggcgataaa cccgggattc
    24061 agacagttga cagtaatgtg aaaaggcgca agctgaatgg cgatgttttt gctggcatta
    24121 attaaagcgg cgttcatcat gctgttggta aacatattgg cgccgggttc tttccatagg
    24181 tttccgacga tattaatgat tctgccgaat tcgtgctgtt tcatgattgc tgcggccgtt
    24241 ttcatagagt cgatataggc gatcgtttta ttcgtaaagg tatttgtcat atcctctata
    24301 tcgcagtttt caaaggtatc cggcgagccg cccggaatgt tgttgatcaa tacatcaagc
    24361 cgtccgcatt gtgatctgat ctcttcaaaa atgccggctc ttgtcttctg atccgacata
    24421 tccccggcca gaacggtgac gcccgcatcc ggatgtttgg cgaggatctc ttcttttacc
    24481 gattcgatat tttcgggaac tcgtgaatta atgacggtat gaaagccatt gtccgccagt
    24541 ttcagagcga tcgctttgcc gatcccctga ctggctccca taataaacgc ggttcgtttt
    24601 gacaactgtc tgcacccctt taccaaaatg gaatctcctt tacatcgtaa aaaaaaatga
    24661 taaaaatagc aaattttatt taaattctga caaaggaaaa acccgccgga caggcgggtg
    24721 ggtgttacat acgatcaata cttttttgtt tcataatgag caattgaata tcaatttaat
    24781 aggaaagatt ttaatgcttg gtctcgaggt ggaatgataa tgaaggtttc taattaataa
    24841 aagctgattg tcagtatttc ttatttagaa tgaggatcga tataaatgct gtacttataa
    24901 ctaacgagga aaataagagt aaaatctgtt ctttgtctag gttgattaaa ttaaaataaa
    24961 atattgtcaa gaaaatgaaa agataaatta aggtcagcat aaaagtatag gctaagctct
    25021 tctgtattat aaactttcct cgttcatctc tttttaatgg taatgatggg aaggtagccc
    25081 atagaacaaa gcttattatt gaaagagtta agatgggaaa agttattgaa ggtaattttg
    25141 tttgcgtaaa tattgatagt gctataaaag ctcccgagac gataatgaaa aaaacaaaag
    25201 atattaaaaa aaagttcttc ttcatttcta ttcctcctct aacaaaaata tattctctac
    25261 actttccttg aaaatctttg ctattttcaa agctaagggc agggagggat tatatttccc
    25321 attctcaatt gaaatgatgg tttgtctgga tacttttaat ttcaaggcta acgtttcctg
    25381 tgaataagaa tgcctctgtc taatttcttt taaccggttt ttcactcata tgtcacctca
    25441 tttcgaaaca acaattgcaa aagatgtaaa gtaaacttca cgtaaagtat actttacatc
    25501 actcccaaat gtttatcaat gtttttcgat ttgttgctga atagtattga aaaaagcctg
    25561 atttttaaaa tcaggcttta acaacttatt acacgtgcaa aaacttcgga agcgtgtcga
    25621 gagacaagcg gtttccgaca aaaaatgaac cgaattcgcc gtagcgcgcg ctgacttcat
    25681 caaagcgcat ttcgtaaaca agttttttga actgaagcac atcatcgctg aagagcgtga
    25741 cgccccattc gtaatcgtca aaaccgacag atcccgtgat aatctgtttg actttgccgg
    25801 catagctccg tccgatcaag ccgtggcttc tcatcaggtt tctgcgttca tccatagaaa
    25861 gcatgtacca gttgtcattg ccgcttcttc ttttatccat cggatagaag cagacgtatt
    25921 tcgcttcagg cagctcagga tacaggcggg cgcggacatg cggattttca tacggatcgc
    25981 cttctccgct tgcgaggtag ttgctcagtt caaccacgga cacgtaagaa taagccggga
    26041 ttgtaaattc agcaagcttt gatttgttaa attcaagctc gatttcgttc agctcttcca
    26101 ttgtcgggcg aagaatcatc agcataaaat cagctttctg tccgacgata ctgtagatgg
    26161 tttgcgagcc tttgccttct ttttgggcga cgccccattt ttcaagcagt cccgtaaatt
    26221 cgtgaataat cgacaggcgc tcatcgctgg ataacatctt ccatgacgtc cagtccattg
    26281 tgcggaaatc gtgaagcgcg taccagccgt caagcgtttg ggcggcttcg ttcgtttttt
    26341 gctgctcact catgtatctt cactcctata tcttttcatt acattgatgc cttcactata
    26401 tcacagttta accgtttcgg ctgtggagaa accttgaata atccgaagcc ttgtgtcaga
    26461 aactatgccg tgaacaaacg gtcaattaaa ttaattagaa aaataagatt tctttttgaa
    26521 agcgctataa tagaagttgg ttatttgaat ttagctggaa gaagagtatg ctgtaaaagt
    26581 aagcgttttt tgtcaacata gaggagggta tatcgtggca gatttattta caaaagtaca
    26641 agaaaaagtc gcaggaaaag atgtgaaaat cgtatttcct gaagggttgg acgaacgtat
    26701 cctggttgcg gtcaacaact tggcgggcaa caaggtatta aagccgatcg tagtcggcaa
    26761 taaagaagac attcaagcaa aagcgaaaga attaaatctt acgcttgacg gcgtggacat
    26821 ttttgacccg catacatatg aaggcatgga agaactcgtt caggctttcg tagaacgccg
    26881 caaaggcaaa gcgacggaag aacaggcccg caaagctttg ctggacgaaa actatttcgg
    26941 cacgatgctt gtgtacaaag gtctcgcaga cggacttgtc agcggagctg cacattctac
    27001 tgctgatacg gtgcgccctg cactgcaaat catcaaaaca aaagaaggcg tgaaaaaaac
    27061 atcaggcgtc ttcatcatgg cccgcggtga cgagcagtat gtgttcgctg attgcgcgat
    27121 caacattgct cctgacagcc aggaccttgc cgaaatcgcc attgaaagcg ccaatacggc
    27181 tcaaatgttt gacattgacc cgcgcgttgc catgctcagc ttctctacaa aaggatcggc
    27241 gaaatcagac gagacggaca aagtggctga agccgtgaaa attgcgaagg aaaaagcgcc
    27301 tgagcttacg cttgacggcg aattccaatt cgacgctgca tttgtgccgt ctgtcgcgga
    27361 gaaaaaagcg ccggactccg acattaaagg agacgcgaat gtatttgtat tcccaagcct
    27421 tgaagcagga aacatcggct acaaaatcgc tcagcgctta ggcggctttg aagcggtcgg
    27481 accgattctg caaggattaa atatgcctgt aaacgatctt tccagaggat gtaatgcgga
    27541 agacgtctac aatcttgcgt taattacggc tgctcaagcg ctgtaatccg caaaagccgg
    27601 cctttacgag ggccggcttt ttttatagaa aaaacgtcac tgcggcccag ccgaacaggg
    27661 acaaacagag agaaccgatc aagcctgctg cgagcgcccg ccagccgtta tgacgaaacg
    27721 ccgatatatg gactttcaaa ccgagacccg ccatcgccat gccgatgaaa acataagaca
    27781 cttgaacaag aaacgcggaa aacgaggctg aaataacgcc tgatgtatgg atggcgctca
    27841 ttccgagaaa tccgaagata aaccagggga tggggagcga agcggcagaa gccgtctttg
    27901 actttccgct gcggcgagcc cgcattccga gcatgaatgc ggccgggacg agcagcgcga
    27961 cccgggtcag tttgacgatc accgccatct cgacggctgc ttttcctccg gcgctgccgg
    28021 ccgccgccgc atgcgccacc tcgtgaagcg ttgccccgca aaaggctccg taagccgcag
    28081 gagaaaagcc caatccatga taagcaagag aatatacaac agtaaaaacg gttcctaata
    28141 acgaaacggc ggccgcgctg atggcggctg cattttcatt tgatctgatc tgcggcgcga
    28201 tcgcggcaat ggcagccgcc ccgcagatcg ctgtgccgca ggctgtcagc g
//
