GCA_024653455.1 - 22 region(s)

Identified secondary metabolite regions using strictness 'relaxed'

gnlProkkaKGDADLMN_3 (original name was: gnl|Prokka|KGDADLMN_3)

Region	Type	From	To	Most similar known cluster		Similarity
Region 3.1	terpene	56,862	77,602

gnlProkkaKGDADLMN_5 (original name was: gnl|Prokka|KGDADLMN_5)

Region	Type	From	To	Most similar known cluster		Similarity
Region 5.1	NRPS	1	25,844	surfactin	NRP:Lipopeptide	47%

gnlProkkaKGDADLMN_8 (original name was: gnl|Prokka|KGDADLMN_8)

Region	Type	From	To	Most similar known cluster		Similarity
Region 8.1	other	90,226	118,476	bacilysin	Other	100%

gnlProkkaKGDADLMN_13 (original name was: gnl|Prokka|KGDADLMN_13)

Region	Type	From	To	Most similar known cluster		Similarity
Region 13.1	transAT-PKS,NRPS,T3PKS	1	76,241	bacillaene	Polyketide+NRP	92%

gnlProkkaKGDADLMN_15 (original name was: gnl|Prokka|KGDADLMN_15)

Region	Type	From	To	Most similar known cluster		Similarity
Region 15.1	transAT-PKS	1	68,671	macrolactin H	Polyketide	100%

gnlProkkaKGDADLMN_16 (original name was: gnl|Prokka|KGDADLMN_16)

Region	Type	From	To	Most similar known cluster		Similarity
Region 16.1	LAP,thiopeptide	1	15,291
Region 16.2	NRPS	26,013	64,394	surfactin	NRP:Lipopeptide	52%

gnlProkkaKGDADLMN_19 (original name was: gnl|Prokka|KGDADLMN_19)

Region	Type	From	To	Most similar known cluster		Similarity
Region 19.1	NRP-metallophore,NRPS	13,612	60,674	bacillibactin	NRP	100%

gnlProkkaKGDADLMN_21 (original name was: gnl|Prokka|KGDADLMN_21)

Region	Type	From	To	Most similar known cluster		Similarity
Region 21.1	PKS-like	6,361	47,605	butirosin A/butirosin B	Saccharide	7%

gnlProkkaKGDADLMN_28 (original name was: gnl|Prokka|KGDADLMN_28)

Region	Type	From	To	Most similar known cluster		Similarity
Region 28.1	transAT-PKS,NRPS,betalactone	1	50,855	fengycin	NRP	73%

gnlProkkaKGDADLMN_35 (original name was: gnl|Prokka|KGDADLMN_35)

Region	Type	From	To	Most similar known cluster		Similarity
Region 35.1	T3PKS	1	26,057

gnlProkkaKGDADLMN_45 (original name was: gnl|Prokka|KGDADLMN_45)

Region	Type	From	To	Most similar known cluster		Similarity
Region 45.1	NRPS-like	13,584	35,157	bacillomycin D	Polyketide+NRP:Lipopeptide	50%

gnlProkkaKGDADLMN_46 (original name was: gnl|Prokka|KGDADLMN_46)

Region	Type	From	To	Most similar known cluster		Similarity
Region 46.1	terpene	11,609	33,492

gnlProkkaKGDADLMN_50 (original name was: gnl|Prokka|KGDADLMN_50)

Region	Type	From	To	Most similar known cluster		Similarity
Region 50.1	transAT-PKS-like	1,119	30,051	difficidin	Polyketide	33%

gnlProkkaKGDADLMN_69 (original name was: gnl|Prokka|KGDADLMN_69)

Region	Type	From	To	Most similar known cluster		Similarity
Region 69.1	transAT-PKS-like	1	17,450	elansolid A1	Polyketide:Trans-AT type I polyketide	30%

gnlProkkaKGDADLMN_72 (original name was: gnl|Prokka|KGDADLMN_72)

Region	Type	From	To	Most similar known cluster		Similarity
Region 72.1	NRPS	1	14,823	brevicidine	NRP	18%

gnlProkkaKGDADLMN_78 (original name was: gnl|Prokka|KGDADLMN_78)

Region	Type	From	To	Most similar known cluster		Similarity
Region 78.1	NRPS	1	12,911	fengycin	NRP	20%

gnlProkkaKGDADLMN_79 (original name was: gnl|Prokka|KGDADLMN_79)

Region	Type	From	To	Most similar known cluster		Similarity
Region 79.1	transAT-PKS-like	1	12,644	difficidin	Polyketide	13%

gnlProkkaKGDADLMN_85 (original name was: gnl|Prokka|KGDADLMN_85)

Region	Type	From	To	Most similar known cluster		Similarity
Region 85.1	NRPS	1	10,738	plipastatin	NRP	15%

gnlProkkaKGDADLMN_88 (original name was: gnl|Prokka|KGDADLMN_88)

Region	Type	From	To	Most similar known cluster		Similarity
Region 88.1	lanthipeptide-class-ii	1	9,429

gnlProkkaKGDADLMN_92 (original name was: gnl|Prokka|KGDADLMN_92)

Region	Type	From	To	Most similar known cluster		Similarity
Region 92.1	transAT-PKS-like	1	8,882	difficidin	Polyketide	20%

gnlProkkaKGDADLMN_97 (original name was: gnl|Prokka|KGDADLMN_97)

Region	Type	From	To	Most similar known cluster		Similarity
Region 97.1	transAT-PKS-like	1	6,686

Region	Type	From	To	Most similar known cluster	Similarity
Region 3.1	terpene	56,862	77,602
Region 5.1	NRPS	1	25,844	surfactin	NRP:Lipopeptide	47%
Region 8.1	other	90,226	118,476	bacilysin	Other	100%
Region 13.1	transAT-PKS,NRPS,T3PKS	1	76,241	bacillaene	Polyketide+NRP	92%
Region 15.1	transAT-PKS	1	68,671	macrolactin H	Polyketide	100%
Region 16.1	LAP,thiopeptide	1	15,291
Region 16.2	NRPS	26,013	64,394	surfactin	NRP:Lipopeptide	52%
Region 19.1	NRP-metallophore,NRPS	13,612	60,674	bacillibactin	NRP	100%
Region 21.1	PKS-like	6,361	47,605	butirosin A/butirosin B	Saccharide	7%
Region 28.1	transAT-PKS,NRPS,betalactone	1	50,855	fengycin	NRP	73%
Region 35.1	T3PKS	1	26,057
Region 45.1	NRPS-like	13,584	35,157	bacillomycin D	Polyketide+NRP:Lipopeptide	50%
Region 46.1	terpene	11,609	33,492
Region 50.1	transAT-PKS-like	1,119	30,051	difficidin	Polyketide	33%
Region 69.1	transAT-PKS-like	1	17,450	elansolid A1	Polyketide:Trans-AT type I polyketide	30%
Region 72.1	NRPS	1	14,823	brevicidine	NRP	18%
Region 78.1	NRPS	1	12,911	fengycin	NRP	20%
Region 79.1	transAT-PKS-like	1	12,644	difficidin	Polyketide	13%
Region 85.1	NRPS	1	10,738	plipastatin	NRP	15%
Region 88.1	lanthipeptide-class-ii	1	9,429
Region 92.1	transAT-PKS-like	1	8,882	difficidin	Polyketide	20%
Region 97.1	transAT-PKS-like	1	6,686

Compact view

gnlProkkaKGDADLMN_3 - Region 1 - terpene

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Location: 56,862 - 77,602 nt. (total: 20,741 nt) Show pHMM detection rules used

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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No matches found.

gnlProkkaKGDADLMN_5 - Region 1 - NRPS

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Location: 1 - 25,844 nt. (total: 25,844 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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core biosynthetic genes

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NRPS/PKS domains

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NRPS/PKS modules

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 25844:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Leu)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg5_2

Search NORINE for peptide: strict or relaxed

AMP-binding (469..867): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFLGCVFK
Nearest Stachelhaus code(s):: Leu DAFFLGCVFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaKGDADLMN_8 - Region 1 - other

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Location: 90,226 - 118,476 nt. (total: 28,251 nt) Show pHMM detection rules used

Region on contig edge.

other: (LmbU or Neocarzinostat or bcpB or frbD or mitE or vlmB or prnB or CaiA or bacilysin or orf2_PTase)

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gnlProkkaKGDADLMN_13 - Region 1 - NRPS,T3PKS,transAT-PKS

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Location: 1 - 76,241 nt. (total: 76,241 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
NRPS: cds(Condensation and (AMP-binding or A-OX))
T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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NRPS/PKS domains

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NRPS/PKS modules

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 76241:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gly - ccmal - ohmal - mal) + (ccmal - mal - ohmal - mal) + (Me-ccmal - ohmal) + (Ala - ccmal - ccmal - Me-ccmal) + (mal - mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg13_5

PKS_AT (8..289): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 87.5%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 100.0
inactive: 46.8
Methoxymalonyl-CoA: 38.9
Methylmalonyl-CoA: 25.3
Propionyl-CoA: 23.1
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg13_6

PKS_AT (7..293): mal

ATSignature: (unknown)

No matches above 50%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 35.4
inactive: 26.4
Methoxymalonyl-CoA: 14.9
Benzoyl-CoA: 14.0
Methylmalonyl-CoA: 9.2
Isobutyryl-CoA: 8.8
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg13_7

PKS_AT (4..282): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 91.7%; inactive: 66.7%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 93.6
inactive: 28.2
Methoxymalonyl-CoA: 25.3
Methylmalonyl-CoA: 11.5
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Propionyl-CoA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg13_12

Search NORINE for peptide: strict or relaxed

CAL_domain (74..476): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 26.7
NH2: 9.4
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (1145..1540): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: gly (Gly)

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGMIWK
Nearest Stachelhaus code(s):: Gly DILQLGMIWK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg13_15

Search NORINE for peptide: strict or relaxed

AMP-binding (492..896): Ala

nrpys: Ala

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: DVSNMAIIYK
Nearest Stachelhaus code(s):: Ala DVSNMAIIYK (88% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaKGDADLMN_15 - Region 1 - transAT-PKS

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Location: 1 - 68,671 nt. (total: 68,671 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))

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NRPS/PKS domains

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 68671:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ohmal - ccmal) + (ccmal) + (ccmal) + (ccmal - mal) + (ccmal - mal) + (ohmal) + (ohmal - mal)
Non-colinear ordering:: ctg15_11 + ctg15_12 + ctg15_13 + ctg15_14 + ctg15_15 + ctg15_16 + ctg15_17 + ctg15_18

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg15_10

PKS_AT (37..315): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 75.0%; inactive: 62.5%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 91.9
inactive: 31.2
Methoxymalonyl-CoA: 26.1
Methylmalonyl-CoA: 19.6
Propionyl-CoA: 16.9
fatty_acid: 13.9
trans-1,2-CPDA: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

gnlProkkaKGDADLMN_16 - Region 1 - LAP,thiopeptide

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Location: 1 - 15,291 nt. (total: 15,291 nt) Show pHMM detection rules used

Region on contig edge.

LAP: ((((goadsporin_like or PF00881 or TIGR03605) and (YcaO or TIGR03604)) or TIGR03882 or TIGR03603 or TIGR03602) and not cyanobactin_synth)
thiopeptide: ((YcaO or TIGR03604) and ((thio_amide and (PF06968 or PF04055 or PF07366)) or Lant_dehydr_C or Lant_dehydr_N or PF07366 or PF06968 or PF04055) or thiostrepton)

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No matches found.

Thiopeptide predictions

No core peptides found.

Thiopeptides

Core peptide predictions

No core peptides found.

gnlProkkaKGDADLMN_16 - Region 2 - NRPS

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Location: 26,013 - 64,394 nt. (total: 38,382 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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		NT	AA		NT	AA

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 2, location 26012 - 64394:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Glu - Leu - D-Leu) + (Val - Asp)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg16_43

Search NORINE for peptide: strict or relaxed

AMP-binding (465..867): Glu

nrpys: Glu

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: gln (Gln)

Stachelhaus prediction details:

Stachelhaus sequence:: DAKDLGVVDK
Nearest Stachelhaus code(s):: Glu DAKDLGVVDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1511..1908): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFMMGMVFK
Nearest Stachelhaus code(s):: Leu DAFMMGMVFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (2550..2939): Leu

nrpys: Leu

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: leu (Leu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWFLGNVVK
Nearest Stachelhaus code(s):: Leu DAWFLGNVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg16_44

Search NORINE for peptide: strict or relaxed

AMP-binding (470..864): Val

nrpys: Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFWIGGTFK
Nearest Stachelhaus code(s):: Val DAFWIGGTFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1502..1904): Asp

nrpys: Asp

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: asp,asn (Asp, Asn)
Single AA prediction:: asp (Asp)

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKVGHIGK
Nearest Stachelhaus code(s):: Asp DLTKVGHIGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaKGDADLMN_19 - Region 1 - NRP-metallophore,NRPS

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Location: 13,612 - 60,674 nt. (total: 47,063 nt) Show pHMM detection rules used

Region on contig edge.

NRP-metallophore: (VibH_like or Cy_tandem or (cds(Condensation and AMP-binding) and ((IBH_Asp and not SBH_Asp) or IBH_His or TBH_Asp or CyanoBH_Asp1 or CyanoBH_Asp2 or IPL or SalSyn or (EntA and EntC) or (GrbD and GrbE) or (FbnL and FbnM) or PvdO or PvdP or (Orn_monoox and not (KtzT or MetRS-like)) or Lys_monoox or VbsL)))
NRPS: cds(Condensation and (AMP-binding or A-OX))

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 13611 - 60674:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gly - Thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg19_40

Search NORINE for peptide: strict or relaxed

AMP-binding (31..435): diOH-Bz

nrpys: diOH-Bz

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Small clusters prediction:: Hydroxy-benzoic acid derivates (diOH-Bz, Sal)
Single AA prediction:: dhb (diOH-Bz)

Stachelhaus prediction details:

Stachelhaus sequence:: PLPAQGVVNK
Nearest Stachelhaus code(s):: diOH-Bz PLPAQGVVNK (100% 8Å match); diOH-Bz or Sal PLPAQGVVNK (94% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg19_42

Search NORINE for peptide: strict or relaxed

AMP-binding (456..855): Gly

nrpys: Gly

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Tiny, hydrophilic, transition to aliphatic (Gly, Ala)
Single AA prediction:: gly (Gly)

Stachelhaus prediction details:

Stachelhaus sequence:: DILQLGLIWK
Nearest Stachelhaus code(s):: Gly DILQLGLIWK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1513..1929): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code(s):: Thr DFWNIGMVHK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaKGDADLMN_21 - Region 1 - PKS-like

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Location: 6,361 - 47,605 nt. (total: 41,245 nt) Show pHMM detection rules used

PKS-like: (t2pks2 or ksIII)

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gnlProkkaKGDADLMN_28 - Region 1 - NRPS,betalactone,transAT-PKS

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Location: 1 - 50,855 nt. (total: 50,855 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS: (cds(PKS_AT and not (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) and (cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS)) or cds(tra_KS and PP-binding)))
NRPS: cds(Condensation and (AMP-binding or A-OX))
betalactone: (HMGL-like and AMP-binding)

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NRPS/PKS products

NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 50855:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Tyr) + (Ile) + (mal - Asn) + (D-Tyr - Asn)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 2, location 0 - 40445:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal - Asn) + (D-Tyr - Asn)

Direct lookup in NORINE database: strict or relaxed

For candidate cluster 3, location 23339 - 50855:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Tyr) + (Ile)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg28_1

Search NORINE for peptide: strict or relaxed

AMP-binding (268..662): Tyr

nrpys: Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: Polar aromatic ring (Tyr, bOH-Tyr)
Single AA prediction:: tyr (Tyr)

Stachelhaus prediction details:

Stachelhaus sequence:: DALSVGEVVK
Nearest Stachelhaus code(s):: Tyr DALSVGEVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1779..2174): Asn

nrpys: Asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: asp,asn (Asp, Asn)
Single AA prediction:: asn (Asn)

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code(s):: Asn DLTKIGEVGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg28_2

Search NORINE for peptide: strict or relaxed

CAL_domain (36..478): pk

minowa: fatty_acid

Prediction, score:

fatty_acid: 621.7
NH2: 18.0
shikimic_acid: 0.0
Acetyl-CoA: 0.0
AHBA: 0.0

AMP-binding (2956..3351): Asn

nrpys: Asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: asp,asn (Asp, Asn)
Single AA prediction:: asn (Asn)

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code(s):: Asn DLTKIGEVGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg28_3

PKS_AT (6..290): mal

ATSignature: Malonyl-CoA

Top 3 matches:: Malonyl-CoA: 62.5%; inactive: 54.2%

minowa: Malonyl-CoA

Prediction, score:

Malonyl-CoA: 71.6
inactive: 31.1
Methoxymalonyl-CoA: 20.5
Propionyl-CoA: 12.6
Methylmalonyl-CoA: 10.8
trans-1,2-CPDA: 0.0
fatty_acid: 0.0
Isobutyryl-CoA: 0.0
Ethylmalonyl-CoA: 0.0
CHC-CoA: 0.0
Benzoyl-CoA: 0.0
Acetyl-CoA: 0.0
3-Methylbutyryl-CoA: 0.0
2-Methylbutyryl-CoA: 0.0

ctg28_22

AMP-binding (12..445): X

nrpys: Asp, Asn, Glu, Gln, Aad

SVM prediction details:

Predicted physicochemical class:: N/A
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: N/A
Single AA prediction:: N/A

Stachelhaus prediction details:

Stachelhaus sequence:: -GLHIAAPVK
Nearest Stachelhaus code(s):: Z-ahmohOrn FGLHIASTCK (56% 8Å match); Ile DGLFIGIPVK (32% 8Å match)
Stachelhaus code match:: 60% (weak)

ctg28_26

Search NORINE for peptide: strict or relaxed

AMP-binding (473..866): Ile

nrpys: Ile

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: ile (Ile)

Stachelhaus prediction details:

Stachelhaus sequence:: DAFFYGITFK
Nearest Stachelhaus code(s):: Ile DAFFYGITFK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg28_27

Search NORINE for peptide: strict or relaxed

AMP-binding (171..563): Tyr

nrpys: Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: Polar aromatic ring (Tyr, bOH-Tyr)
Single AA prediction:: tyr (Tyr)

Stachelhaus prediction details:

Stachelhaus sequence:: DGTITAEVAK
Nearest Stachelhaus code(s):: Tyr DGTITAEVAK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaKGDADLMN_35 - Region 1 - T3PKS

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Location: 1 - 26,057 nt. (total: 26,057 nt) Show pHMM detection rules used

Region on contig edge.

T3PKS: (Chal_sti_synt_C or Chal_sti_synt_N)

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No matches found.

gnlProkkaKGDADLMN_45 - Region 1 - NRPS-like

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Location: 13,584 - 35,157 nt. (total: 21,574 nt) Show pHMM detection rules used

Region on contig edge.

NRPS-like: cds((PP-binding or NAD_binding_4) and (AMP-binding or A-OX))

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gnlProkkaKGDADLMN_46 - Region 1 - terpene

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Location: 11,609 - 33,492 nt. (total: 21,884 nt) Show pHMM detection rules used

Region on contig edge.

terpene: (Terpene_synth or Terpene_synth_C or phytoene_synt or Lycopene_cycl or terpene_cyclase or NapT7 or fung_ggpps or fung_ggpps2 or trichodiene_synth or TRI5)

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gnlProkkaKGDADLMN_50 - Region 1 - transAT-PKS-like

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Location: 1,119 - 30,051 nt. (total: 28,933 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)

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NRPS/PKS products

Predicted core structure(s)

For candidate cluster 1, location 1118 - 30051:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (mal)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

gnlProkkaKGDADLMN_69 - Region 1 - transAT-PKS-like

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Location: 1 - 17,450 nt. (total: 17,450 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)

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NRPS/PKS products

Predicted core structure(s)

For candidate cluster 1, location 0 - 17450:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (ohmal - ccmal) + (ohmal) + (mal)
Non-colinear ordering:: ctg69_1 + ctg69_2 + ctg69_3 + ctg69_4

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

gnlProkkaKGDADLMN_72 - Region 1 - NRPS

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Location: 1 - 14,823 nt. (total: 14,823 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 14823:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (Gln - Pro) + (D-Asn)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg72_1

Search NORINE for peptide: strict or relaxed

AMP-binding (760..1165): Gln

nrpys: Gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: gln (Gln)

Stachelhaus prediction details:

Stachelhaus sequence:: DAQDLGVVDK
Nearest Stachelhaus code(s):: Gln DAQDLGVVDK (100% 8Å match); Ile DAQDLGVVDK (74% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1809..2205): Pro

nrpys: Pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
Small clusters prediction:: pro (Pro)
Single AA prediction:: pro (Pro)

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code(s):: Pro DVQFIAHVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg72_2

Search NORINE for peptide: strict or relaxed

AMP-binding (268..663): Asn

nrpys: Asn

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: asp,asn (Asp, Asn)
Single AA prediction:: asn (Asn)

Stachelhaus prediction details:

Stachelhaus sequence:: DLTKIGEVGK
Nearest Stachelhaus code(s):: Asn DLTKIGEVGK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1778..2076): Ser

nrpys: Ser

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: N/A
Small clusters prediction:: ser (Ser)
Single AA prediction:: ser (Ser)

Stachelhaus prediction details:

Stachelhaus sequence:: DVWHFSL--K
Nearest Stachelhaus code(s):: Ser DVWHFSLVDK (82% 8Å match)
Stachelhaus code match:: 80% (moderate)

gnlProkkaKGDADLMN_78 - Region 1 - NRPS

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Location: 1 - 12,911 nt. (total: 12,911 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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NRPS/PKS substrates

Predicted core structure(s)

For candidate cluster 1, location 0 - 12911:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-Orn) + (Tyr - D-Thr)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg78_1

Search NORINE for peptide: strict or relaxed

AMP-binding (165..570): Orn

nrpys: Orn

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Long positively charged side chain (Orn, Lys, Arg)
Small clusters prediction:: Orn and hydroxy-Orn specific (Orn, OH-Orn)
Single AA prediction:: orn (Orn)

Stachelhaus prediction details:

Stachelhaus sequence:: DVGEVGSIDK
Nearest Stachelhaus code(s):: Orn DVGEVGSIDK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg78_2

Search NORINE for peptide: strict or relaxed

AMP-binding (474..867): Tyr

nrpys: Tyr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aromatic (Phe, Tyr, diOH-Bz, Ph-Gly, bOH-Tyr)
Large clusters prediction:: Aromatic side chain (Phe, Trp, Ph-Gly, Tyr, bOH-Tyr)
Small clusters prediction:: Polar aromatic ring (Tyr, bOH-Tyr)
Single AA prediction:: tyr (Tyr)

Stachelhaus prediction details:

Stachelhaus sequence:: DGTLTAEVAK
Nearest Stachelhaus code(s):: Tyr DGTLTAEVAK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1509..1905): Thr

nrpys: Thr

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Aliphatic chain or phenyl group with -OH (Ser, Thr, Dhpg, Hpg)
Small clusters prediction:: thr (Thr)
Single AA prediction:: thr (Thr)

Stachelhaus prediction details:

Stachelhaus sequence:: DFWNIGMVHK
Nearest Stachelhaus code(s):: Thr DFWNIGMVHK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaKGDADLMN_79 - Region 1 - transAT-PKS-like

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Location: 1 - 12,644 nt. (total: 12,644 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)

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Predicted core structure(s)

For candidate cluster 1, location 0 - 12644:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (mal) + (ccmal)
Non-colinear ordering:: ctg79_1 + ctg79_2

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

gnlProkkaKGDADLMN_85 - Region 1 - NRPS

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Location: 1 - 10,738 nt. (total: 10,738 nt) Show pHMM detection rules used

Region on contig edge.

NRPS: cds(Condensation and (AMP-binding or A-OX))

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Predicted core structure(s)

For candidate cluster 1, location 0 - 10738:

Rough prediction of core scaffold based on assumed PKS/NRPS colinearity; tailoring reactions not taken into account

Polymer prediction:: (D-X) + (Pro - Gln)

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

NRPS/PKS substrate predictions

ctg85_1

Search NORINE for peptide: strict or relaxed

AMP-binding (469..866): Pro

nrpys: Pro

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Cyclic aliphatic chain (polar NH2 group) (Pro, Hpr)
Small clusters prediction:: pro (Pro)
Single AA prediction:: pro (Pro)

Stachelhaus prediction details:

Stachelhaus sequence:: DVQFIAHVVK
Nearest Stachelhaus code(s):: Pro DVQFIAHVVK (100% 8Å match)
Stachelhaus code match:: 100% (strong)

AMP-binding (1500..1901): Gln

nrpys: Gln

SVM prediction details:

Predicted physicochemical class:: hydrophilic (Arg, Asp, Glu, Asn, Lys, Gln, Orn, Aad)
Large clusters prediction:: Aliphatic chain with H-bond donor (Asp, Asn, Glu, Gln, Aad)
Small clusters prediction:: glu,gln (Glu, Gln)
Single AA prediction:: glu (Glu)

Stachelhaus prediction details:

Stachelhaus sequence:: DAWHFGSVEK
Nearest Stachelhaus code(s):: Gln DAWHFGSVEK (100% 8Å match); Glu DAWHFGSVEK (94% 8Å match)
Stachelhaus code match:: 100% (strong)

ctg85_2

AMP-binding (165..558): X

nrpys: Ala, Val

SVM prediction details:

Predicted physicochemical class:: hydrophobic-aliphatic (Ala, Gly, Val, Leu, Ile, Abu, Ival, Ser, Thr, Hpg, Dhpg, Cys, Pro, Hpr)
Large clusters prediction:: Apolar, aliphatic (Gly, Ala, Val, Leu, Ile, Abu, Ival)
Small clusters prediction:: Aliphatic, branched hydrophobic (Val, Leu, Ile, Abu, Ival)
Single AA prediction:: val (Val)

Stachelhaus prediction details:

Stachelhaus sequence:: DVFWIGGTFK
Nearest Stachelhaus code(s):: Ala or Val DVFWIGGTFK (100% 8Å match); Val DVFWIGGTFK (91% 8Å match)
Stachelhaus code match:: 100% (strong)

gnlProkkaKGDADLMN_88 - Region 1 - lanthipeptide-class-ii

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Location: 1 - 9,429 nt. (total: 9,429 nt) Show pHMM detection rules used

Region on contig edge.

lanthipeptide-class-ii: cds(LANC_like and DUF4135)

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core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

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Gene overview

KnownClusterBlast

Lanthipeptides

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Similar known gene clusters from MIBiG 3.1

No matches found.

Lanthipeptide predictions

Lanthipeptide(s) for ctg88_6

ctg88_5

Leader:

MSEKQIERTIRAWKDPEFRKTLSDVADHPSGSIEARQLSMLGS

Core:

EENVNPMTTPVSPAPTVVIRVSLKVCPTFKIKCKV

Core with dehydrations:

EENVNPMDhbDhbPVDhaPAPDhbVVIRVDhaLKVCysPDhbFKIKCysKV

MIBiG 3.1 matches for ctg88_5

14.3% BGC0000553 (SSGG_RS09925): Lanthipeptide: SRO15-2212

20

RVSLKVC

26

+VSL VC

4

QVSLLVC

10

antiSMASH-DB 4.0 matches for ctg88_5

100.0% NZ_CP039297.1and 2 others:

NZ_CP040378.1 Lanthipeptides: D1120_RS00435_lanthipeptideNZ_CP059318.1 Lanthipeptides: HZT45_RS00565_lanthipeptide

Lanthipeptides: E4T61_RS00570_lanthipeptide

1

EENVNPMTTPVSPAPTVVIRVSLKVCPTFKIKCKV

35

EENVNPMTTPVSPAPTVVIRVSLKVCPTFKIKCKV

1

EENVNPMTTPVSPAPTVVIRVSLKVCPTFKIKCKV

35

97.1% NZ_CP040672.1and 1 other:

NZ_CP087137.1 Lanthipeptides: LOK79_RS00585_lanthipeptide

Lanthipeptides: FGE23_RS05605_lanthipeptide

1

EENVNPMTTPVSPAPTVVIRVSLKVCPTFKIKCKV

35

E+NVNPMTTPVSPAPTVVIRVSLKVCPTFKIKCKV

1

EDNVNPMTTPVSPAPTVVIRVSLKVCPTFKIKCKV

35

42.9% NC_018499.1and 5 others:

NC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27845_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27840_lanthipeptideNC_018499.1 Lanthipeptides: BCK_RS27835_lanthipeptide

Lanthipeptides: BCK_RS27845_lanthipeptide

3

NVNPMTTPVSPAPTVVIRVSLKVCPTFKIKCK

34

+VNP TTP +P ++ VSL +CPT K K

2

DVNPETTPATP---TIVAVSLGICPTTKCTSK

30

with 43 more sequence matches

42.9% NZ_CP023481.1and 2 others:

NZ_JALARN010000006.1 Lanthipeptides: MOE03_RS17410_lanthipeptideNZ_JAQCPU010000013.1 Lanthipeptides: PG077_RS20425_lanthipeptide

Lanthipeptides: COP00_RS24795_lanthipeptide

5

NPMTTPVSPAPTVVIRV---SLKVCPTFKIKC

33

N TP S V +RV S+K CP+FK KC

1

NDEITPQSTVVCVSLRVCKWSIKYCPSFKRKC

32

42.9% NZ_PIJH01000018.1: Lanthipeptides: CV632_RS18055_lanthipeptide

9

TPVSPAPTVV---IRV---SLKVCPTFKIKC

33

T VSP T+V +R+ SL+ CP+FK+KC

2

TEVSPQSTIVCVSLRICNWSLRFCPSFKVKC

32

40.0% NC_009328.1: Lanthipeptides: GTNG_RS18990_lanthipeptide

9

TPVSPAPTVV---IRV---SLKVCPTFKIKC

33

T VSP T+V +R+ SL+ CP+FK++C

2

TEVSPQSTIVCVSLRICNWSLRFCPSFKVRC

32

40.0% NZ_CP013862.1and 1 other:

NZ_CP013862.1 Lanthipeptides: AOX59_RS09365_lanthipeptide

Lanthipeptides: AOX59_RS09365_lanthipeptide

3

NVNPMTTPVSPAPTVVIRVSLKVCPTFK

30

+V+P TTP S A I VS CPT K

2

DVDPQTTPSSVA--CGIAVSALFCPTTK

27

40.0% NZ_CP015591.1and 15 others:

NZ_CP078085.1 Lanthipeptides: KU891_RS29355_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29350_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29345_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29340_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29335_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29930_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29925_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29920_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29910_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23050_lanthipeptide

Lanthipeptides: A7A70_RS27550_lanthipeptide

3

NVNPMTTPVSPAPTVV---IRVSLKVCPTFK

30

+VNP TTP + PT+V I ++ +CPT K

2

DVNPETTPAT--PTIVEATIAATVSICPTTK

30

40.0% NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27205_lanthipeptide

Lanthipeptides: EXW52_RS27205_lanthipeptide

3

NVNPMTTPVSPAPTVVIRVSLKVCPTFKIKCK

34

+V+P TTP +P T+V+ +S+ +CPT K K

2

DVSPETTPATP--TIVVAISVGLCPTTKCTSK

31

40.0% NZ_JALAJI010000006.1and 3 others:

NZ_JALAOO010000008.1 Lanthipeptides: MOC69_RS16910_lanthipeptideNZ_JALAXE010000008.1 Lanthipeptides: MOF11_RS14910_lanthipeptideNZ_JALAXI010000013.1 Lanthipeptides: MOE73_RS14185_lanthipeptide

Lanthipeptides: MOB90_RS08905_lanthipeptide

5

NPMTTPVSPAPTVVIRV---SLKVCPTFKIKC

33

N TP S V +R+ S+K CP+FK KC

1

NDEITPQSTVVCVSLRLCKWSIKYCPSFKKKC

32

40.0% NZ_JALANL010000003.1and 3 others:

NZ_MUEI01000003.1 Lanthipeptides: BV582_RS23575_lanthipeptideNZ_NIJN01000002.1 Lanthipeptides: CHCC5027_RS22460_lanthipeptideNZ_NIMF01000037.1 Lanthipeptides: CHCC14814_RS22115_lanthipeptide

Lanthipeptides: MOC63_RS03255_lanthipeptide

5

NPMTTPVSPAPTVVIRV---SLKVCPTFKIKC

33

N TP S V +R+ S+K CP+FK KC

1

NDEITPQSTVVCVSLRICKWSIKYCPSFKRKC

32

40.0% NZ_NUML01000015.1: Lanthipeptides: COD66_RS20140_lanthipeptide

3

NVNPMTTPVSPAPTVVIRVSLKVCPTFKIKCK

34

+V+P TTP +P T+V+ +S+ +CPT K K

2

DVSPETTPATP--TIVVGISVGLCPTTKCTSK

31

38.5% NZ_CP009280.1and 1 other:

NZ_CP009280.1 Lanthipeptides: P40081_RS37160_lanthipeptide

Lanthipeptides: P40081_RS37160_lanthipeptide

3

NVNPMTTPV--SPAPTVV--IRVSLKVCPTFKIKCK

34

+VNP TTP+ S P V+ + +S +CPT K K

3

DVNPETTPLTTSSWPCVIGAVDISANLCPTTKCTSK

38

37.1% NZ_CM000721.1and 9 others:

NZ_CP015591.1 Lanthipeptides: A7A70_RS27555_lanthipeptideNZ_CP078085.1 Lanthipeptides: KU891_RS29360_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29940_lanthipeptideNZ_CP085411.1 Lanthipeptides: LIT28_RS29935_lanthipeptideNZ_NUBO01000052.1 Lanthipeptides: CN575_RS29785_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptideNZ_QNUC01000031.1 Lanthipeptides: DN396_RS23040_lanthipeptide

Lanthipeptides: BCERE0010_RS29355_lanthipeptide

3

NVNPMTTPVSPA-PTVVIRVSLKVCPTFK

30

+VNP TTP +P I V+ +CPT K

2

DVNPETTPATPTIIGATIAVTASLCPTTK

30

37.1% NZ_CP036019.1and 7 others:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27190_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27180_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27175_lanthipeptideNZ_CP036019.1 Lanthipeptides: EXW52_RS27170_lanthipeptide

Lanthipeptides: EXW52_RS27190_lanthipeptide

3

NVNPMTTPVSPAPTVVIRVSLKVCPTFKIKCK

34

+V+P TTP +P T+V+ +S+ +CPT + K

2

DVSPETTPATP--TIVVAISVGLCPTNRCTSK

31

37.1% NZ_FOHE01000009.1: Lanthipeptides: BMX40_RS20255_lanthipeptide

2

ENVNPMTTPVSPAPTVVIRVSLKVCPTFKIKC

33

E V P +T V + + + S+K CP+FK KC

2

EEVTPQSTVVCVSLRLC-KWSIKYCPSFKRKC

32

37.1% NZ_MLKL01000042.1: Lanthipeptides: BKK45_RS27405_lanthipeptide

3

NVNPMTTPVSPAPTVVIRVSLKVCPT

28

+VNP TTP +P ++ VS+K+CPT

2

DVNPETTPATP---TIVAVSVKLCPT

24

34.3% NZ_CACZYW010000004.1and 3 others:

NZ_CACZYW010000004.1 Lanthipeptides: HUF10_RS02820_lanthipeptideNZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptideNZ_FNHR01000005.1 Lanthipeptides: BLQ37_RS05585_lanthipeptide

Lanthipeptides: HUF10_RS02820_lanthipeptide

8

TTPVSPAPTVVIRVSL----KVCPT

28

TTP +PA V++ VS K CPT

1

TTPATPATPVIVAVSAYVSDKTCPT

25

34.3% NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27195_lanthipeptide

Lanthipeptides: EXW52_RS27195_lanthipeptide

3

NVNPMTTPVSPAPTVVIRVSLKVCPT

28

+V+P TTP +P T+V+ +S+ +CPT

2

DVSPETTPATP--TIVVAISVGLCPT

25

34.3% NZ_JAMDLZ010000027.1: Lanthipeptides: M5W82_RS15520_lanthipeptide

2

ENVNPMTTPVSPAPTVVIRVSLKVCPTFK

30

+ P TP+ TV I +SL CPT K

1

SEIQPKWTPL----TVTIPISLAGCPTTK

25

34.3% NZ_JAQQWR010000009.1: Lanthipeptides: PQ473_RS20190_lanthipeptide

2

ENVNPMTTPVSPAPTV--VIRVSLKVC

26

+VNP TTP+ A +V I S+K C

1

SDVNPETTPLCVAYSVGATIVFSVKHC

27

34.2% NC_006322.1and 7 others:

NC_006322.1 Lanthipeptides: BLI_RS20290_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_CP033218.1 Lanthipeptides: D9Y32_RS07810_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_LQYL01000021.1 Lanthipeptides: B4090_RS08830_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptideNZ_NIMP01000036.1 Lanthipeptides: CHCC14566_RS11870_lanthipeptide

Lanthipeptides: BLI_RS20290_lanthipeptide

2

ENVNPMTTPVSPAP----TVVIRVSLKVCPTFK

30

+VNP TTP + + T + VS +CPT K

1

NDVNPETTPATTSSWTCITAGVTVSASLCPTTK

33

31.4% NZ_JAHHYI010000012.1: Lanthipeptides: KM925_RS25405_lanthipeptide

3

NVNPMTTP--VSPAPTVVIRVSLKVC

26

+V P TTP V TV I +S +C

2

DVQPETTPACVGAGITVGIAISKLLC

27

30.8% NZ_CP009288.1and 3 others:

NZ_CP009288.1 Lanthipeptides: PDUR_RS29295_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptideNZ_CP076607.1 Lanthipeptides: KP014_RS01575_lanthipeptide

Lanthipeptides: PDUR_RS29295_lanthipeptide

3

NVNPMTTPVSPAP----TVVIRVSLKVCPTFK

30

+VNP TT ++ + T + VS +CPT K

3

DVNPETTILTTSSWTCITAGVTVSASLCPTTK

34

28.6% NZ_WIXN01000006.1and 1 other:

NZ_WIXN01000006.1 Lanthipeptides: GHD25_RS06900_lanthipeptide

Lanthipeptides: GHD25_RS06900_lanthipeptide

15

PTVVIRVSLKVCPT

28

PT +I VSL VCPT

9

PTTIIPVSLAVCPT

22

25.7% NZ_BOSN01000007.1and 5 others:

NZ_BOSN01000007.1 Lanthipeptides: KJS43_RS18000_lanthipeptideNZ_JAHHXV010000040.1 Lanthipeptides: KM914_RS20955_lanthipeptideNZ_JAHHXV010000040.1 Lanthipeptides: KM914_RS20955_lanthipeptideNZ_LT745762.1 Lanthipeptides: B2C77_RS21505_lanthipeptideNZ_LT745762.1 Lanthipeptides: B2C77_RS21505_lanthipeptide

Lanthipeptides: KJS43_RS18000_lanthipeptide

15

PTVVIRVSLKVCPTFK

30

P +I VSL +CPT K

8

PATIIPVSLAICPTTK

23

25.7% NZ_CP028922.1: Lanthipeptides: allorf_4058819_4059013_lanthipeptide

7

MTTPVSPAPTVVIRVSLKVCPTFKIKCKV

35

+ TP S + K CPT+ KC +

7

ICTPGSCDGDRCWLTTFKGCPTYGPKCDI

35

25.7% NZ_CP067069.1and 13 others:

NZ_CP085413.1 Lanthipeptides: LIS80_RS25350_lanthipeptideNZ_JH792105.1 Lanthipeptides: II5_RS26960_lanthipeptideNZ_JH792240.1 Lanthipeptides: IIK_RS26240_lanthipeptideNZ_MOOT01000061.1 Lanthipeptides: BK765_RS23985_lanthipeptideNZ_NTUF01000024.1 Lanthipeptides: CN379_RS26680_lanthipeptideNZ_NVCZ01000001.1 Lanthipeptides: COK75_RS01180_lanthipeptideNZ_NVDK01000008.1 Lanthipeptides: COK95_RS05665_lanthipeptideNZ_NVEA01000001.1 Lanthipeptides: COL15_RS00010_lanthipeptideNZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08190_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20675_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19560_lanthipeptideNZ_WBPE01000025.1 Lanthipeptides: F8161_RS14435_lanthipeptideNZ_WBPK01000016.1 Lanthipeptides: F8167_RS15685_lanthipeptide

Lanthipeptides: JCR32_RS24620_lanthipeptide

2

ENVNPMTTPVSPAPTVVIRVSLKVC

26

+V P TTP+ + I S+K+C

1

SDVQPETTPLCVGVIIGITASIKIC

25

25.7% NZ_JACSMH010000008.1and 2 others:

NZ_JACSMX010000006.1 Lanthipeptides: KNQ03_RS15615_lanthipeptideNZ_JACSMZ010000005.1 Lanthipeptides: KNQ06_RS16025_lanthipeptide

Lanthipeptides: KNP89_RS14470_lanthipeptide

3

NVNPMTTPVSPAPTVVIRVSLKVC

26

+V P TTP V + +SL C

2

DVQPETTPFCVGVIVGVTISLSKC

25

25.7% NZ_JACYTN010000030.1: Lanthipeptides: allorf_08178_08354_lanthipeptide

7

MTTPVSPAPTVVIRVSLKVCPTFKIKCKV

35

+ TP S + + K CPT+ KC +

7

ICTPGSCSGDSCWLTTFKGCPTYGPKCDI

35

25.7% NZ_LDKE01000067.1: Lanthipeptides: ABB04_RS19960_lanthipeptide

2

ENVNPMTTPVSPAPTVVIRVSLKVC

26

+V P TTP+ + I S+K+C

1

SDVKPETTPLCVGVIIGITASIKIC

25

25.7% NZ_NIST01000001.1: Lanthipeptides: CD001_RS09870_lanthipeptide

5

NPMTTPVSPAPTVVIRVSLKVCPT

28

+ TP T+ RVSL C T

2

GGICTPSCLTGTLNCRVSLTFCRT

25

23.8% NZ_CP010976.1: Lanthipeptides: UB51_RS20985_lanthipeptide

3

NVNPMTTPVSPAPTVVI

19

+VNP TTP + PT+VI

2

DVNPETTPAT--PTIVI

16

22.9% NZ_CP016020.1and 34 others:

NZ_CP067069.1 Lanthipeptides: JCR32_RS24625_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25380_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25375_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25370_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25365_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25360_lanthipeptideNZ_CP085413.1 Lanthipeptides: LIS80_RS25355_lanthipeptideNZ_JH792105.1 Lanthipeptides: II5_RS26955_lanthipeptideNZ_LDKE01000067.1 Lanthipeptides: ABB04_RS19955_lanthipeptideNZ_LDKE01000067.1 Lanthipeptides: ABB04_RS19940_lanthipeptideNZ_LDKE01000067.1 Lanthipeptides: ABB04_RS19935_lanthipeptideNZ_MOOT01000061.1 Lanthipeptides: BK765_RS23995_lanthipeptideNZ_MOOT01000061.1 Lanthipeptides: BK765_RS23990_lanthipeptideNZ_NVEA01000001.1 Lanthipeptides: COL15_RS00005_lanthipeptideNZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08185_lanthipeptideNZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08180_lanthipeptideNZ_PIYQ01000022.1 Lanthipeptides: CW365_RS08175_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20670_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20665_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20660_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20655_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20650_lanthipeptideNZ_WBOZ01000055.1 Lanthipeptides: F8156_RS20645_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19555_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19550_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19545_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19540_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19535_lanthipeptideNZ_WBPC01000027.1 Lanthipeptides: F8159_RS19530_lanthipeptideNZ_WBPE01000025.1 Lanthipeptides: F8161_RS14445_lanthipeptideNZ_WBPE01000025.1 Lanthipeptides: F8161_RS14440_lanthipeptideNZ_WBPK01000016.1 Lanthipeptides: F8167_RS15680_lanthipeptideNZ_WBPK01000016.1 Lanthipeptides: F8167_RS15675_lanthipeptideNZ_WBPK01000016.1 Lanthipeptides: F8167_RS15670_lanthipeptide

Lanthipeptides: A9C19_RS17970_lanthipeptide

2

ENVNPMTTPVSPAPTVVIRVSLKVC

26

+V P TTP+ + + S+K+C

1

SDVQPETTPLCVGVIIGLTTSIKIC

25

22.9% NZ_CP036019.1and 1 other:

NZ_CP036019.1 Lanthipeptides: EXW52_RS27165_lanthipeptide

Lanthipeptides: EXW52_RS27165_lanthipeptide

3

NVNPMTTPVSPAPTVVIRVSLKVCPTF

29

+VNP T P + P ++ ++ ++CP+

2

DVNPETIPATATP-ILANLTKELCPSI

27

22.9% NZ_CP063142.1and 1 other:

NZ_CP063142.1 Lanthipeptides: HPB58_RS21460_lanthipeptide

Lanthipeptides: HPB58_RS21460_lanthipeptide

16

TVVIRVSLKVCPT

28

TV I +SL CPT

8

TVTIPISLAACPT

20

22.9% NZ_CP063142.1and 5 others:

NZ_CP063142.1 Lanthipeptides: HPB58_RS21455_lanthipeptideNZ_JALAMS010000001.1 Lanthipeptides: MOC86_RS01475_lanthipeptideNZ_JALAMS010000001.1 Lanthipeptides: MOC86_RS01475_lanthipeptideNZ_LWAI01000057.1 Lanthipeptides: A4U60_RS22255_lanthipeptideNZ_LWAI01000057.1 Lanthipeptides: A4U60_RS22255_lanthipeptide

Lanthipeptides: HPB58_RS21455_lanthipeptide

16

TVVIRVSLKVCPTFK

30

TV I +SL CPT +

8

TVTIPISLAACPTTQ

22

22.9% NZ_CP101913.1and 1 other:

NZ_CP101913.1 Lanthipeptides: NP440_RS09140_lanthipeptide

Lanthipeptides: NP440_RS09140_lanthipeptide

15

PTVVIRVSLKVCPTFK

30

PTV I +S +CPT +

8

PTVTIPISAAICPTTQ

23

22.9% NZ_KE384107.1: Lanthipeptides: G586_RS26715_lanthipeptide

11

VSPAPTVVIRVSLKVCPTFK

30

V+P ++I S CPT K

6

VAPVVPIIIAASTAFCPTIK

25

22.9% NZ_KQ040792.1and 1 other:

NZ_KQ040792.1 Lanthipeptides: WH45_RS23705_lanthipeptide

Lanthipeptides: WH45_RS23705_lanthipeptide

15

PTVVIRVSLKVCPTFK

30

P +I VSL +CPT +

9

PATIIPVSLAICPTTR

24

22.9% NZ_LDFC01000091.1: Lanthipeptides: ABE61_RS23570_lanthipeptide

13

PAPTVVIRVSLKVC

26

P PTVV VS+ +C

6

PPPTVVSSVSIWIC

19

22.9% NZ_LT985747.1: Lanthipeptides: C8268_RS22865_lanthipeptide

7

MTTPVSPAPTVVIRVSLKVCPTFKIKCKV

35

+ TP S + + + + CPT+ KC +

7

ICTPGSCSGNNCVLTTWRGCPTYGPKCDI

35

22.9% NZ_NUML01000015.1: Lanthipeptides: COD66_RS20280_lanthipeptide

3

NVNPMTTPVSPAPTVVIRVSLKVCPTF

29

++NP T P +P P +++ ++ ++CP+

2

DMNPETIPATPTP-ILVNLTKELCPSI

27

20.0% NZ_BQME02000001.1and 5 others:

NZ_BQME02000001.1 Lanthipeptides: MFF31_RS04080_lanthipeptideNZ_BQME02000001.1 Lanthipeptides: MFF31_RS04090_lanthipeptideNZ_BQME02000001.1 Lanthipeptides: MFF31_RS04090_lanthipeptideNZ_BQME02000001.1 Lanthipeptides: MFF31_RS04085_lanthipeptideNZ_BQME02000001.1 Lanthipeptides: MFF31_RS04085_lanthipeptide

Lanthipeptides: MFF31_RS04080_lanthipeptide

16

TVVIRVSLKVCPTFK

30

T++I +SL CPT +

6

TIIIPISLAACPTTR

20

18.9% NZ_CM001792.1and 1 other:

NZ_CM001792.1 Lanthipeptides: C794_RS17975_lanthipeptide

Lanthipeptides: C794_RS17975_lanthipeptide

9

TPVSPAPTVVIRVSLKVCPT

28

+P++P+ + +SL CPT

8

SPLTPSSGSCVAISLAFCPT

27

17.1% NZ_MJEJ02000054.1and 3 others:

NZ_MJEJ02000054.1 Lanthipeptides: BH683_RS28810_lanthipeptideNZ_QJSP01000005.1 Lanthipeptides: DFR67_RS30760_lanthipeptideNZ_QJSP01000005.1 Lanthipeptides: DFR67_RS30760_lanthipeptide

Lanthipeptides: BH683_RS28810_lanthipeptide

21

VSLKVCPTFK

30

+S+ +CPTFK

12

LSVALCPTFK

21

Legend:

Dha: Didehydroalanine
Dhb: Didehydrobutyrine

Lanthipeptides

Core peptide predictions

ctg88_5 - Class II

Cleavage pHMM score: -3.30

RODEO score: 0

Monoisotopic mass: 3716.1 Da

Molecular weight: 3718.5 Da

Number of bridges: 2

Alternative weights: (assuming N unmodified Ser/Thr residues); 3736.5 Da N = 1; 3754.5 Da N = 2; 3772.5 Da N = 3; 3790.6 Da N = 4

gnlProkkaKGDADLMN_92 - Region 1 - transAT-PKS-like

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Location: 1 - 8,882 nt. (total: 8,882 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

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Gene details

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Gene overview

NRPS/PKS domains

KnownClusterBlast

NRPS/PKS modules

Gene/CDS overview

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Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

Module view

Legend

NRPS/PKS products

Predicted core structure(s)

For candidate cluster 1, location 0 - 8882:

Rough prediction of core scaffold based on assumed PKS linker matching; tailoring reactions not taken into account

Polymer prediction:: (mal) + (ohmal)
Non-colinear ordering:: ctg92_2 + ctg92_1

Direct lookup in NORINE database: strict or relaxed

Link to NORINE database query form

gnlProkkaKGDADLMN_97 - Region 1 - transAT-PKS-like

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Location: 1 - 6,686 nt. (total: 6,686 nt) Show pHMM detection rules used

Region on contig edge.

transAT-PKS-like: cds(ATd and (PKS_KS or ene_KS or mod_KS or hyb_KS or itr_KS or tra_KS) and not PKS_AT)

Legend:

core biosynthetic genes

additional biosynthetic genes

transport-related genes

regulatory genes

other genes

resistance

reset view

zoom to selection

Gene details

Select a gene to view the details available for it

Gene overview

NRPS/PKS domains

KnownClusterBlast

Gene/CDS overview

Filter:

Automatically zoom to filtered/selected features

Identifier	Product	Length		Function	Sequence		NCBI Blast	Filter details
		NT	AA		NT	AA

Detailed domain annotation

Selected features only

Show module domains

Similar known gene clusters from MIBiG 3.1

No matches found.