LOCUS       c00001_gnlPro..        24536 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|JJIKBNNI_1.
ACCESSION   c00001_gnlPro..
VERSION     c00001_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-06 15:47:45
            Original ID  :: gnl|Prokka|JJIKBNNI_1
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2068006
            Orig. end    :: 2092542
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24536
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2078006:2082542]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14536
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24536
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24536
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="4"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             581..1102
                     /locus_tag="ctg1_1726"
                     /transl_table=11
                     /translation="MSFLELARKRCSIRKYAPKNVEQEKIDYILEAARLAPSAVNYQPW
                     YFVWVQSAEGKAKLQECYPREWFKQAPYYLIVCGDHQQSWKRGDHKDHMDIDTAIATEH
                     ICLAAAEQGLGTCWVCNFDTELCRKHFKIPETIEPVVLIPFGYPSDPALFDETPKKRKP
                     IEEIIKRESF"
     CDS             1104..1670
                     /locus_tag="ctg1_1727"
                     /transl_table=11
                     /translation="MLYIEVLLLAIGLSMDSLAVSVTGGAVLKNNCTAGNIIKIASVLG
                     IFQAGMTVIGYTMGLGFEKYICAFDHWIAFTLLLYLGGKMIYDSTKEEEEDGKFDPLCN
                     RTLCGLGIATSIDALAVGISLAILKSPLLLQASTIGVVTFAISAFGVYFGNRFGKRIDL
                     KLDLIGGLILIGIGTKILIEHVFFS"
     CDS             1715..3439
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) ILVD_EDD"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1728"
                     /sec_met_domain="ILVD_EDD (E-value: 1e-180, bitscore:
                     599.7, seeds: 918, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSQQLRKLAPELDSLRLGSGWKIDELSKPQIIVESSYGHSHPGS
                     AHLDKLVDEAGIGIKEKGGRAANYFVTDICDGEAQGHDGMNYSLVSRDIMAAMMEIHVK
                     ATPFDAGVFIASCDKSVPAHLMAIARLDMPAIFMPGGIMKAGPNLLTLEQIGTYSAQYE
                     RKEITEEQFMVYKRDACPDCGACSFMGTASTMQVMAEALGIALPGSALIPAHLPELKET
                     ARKAGEHALGLAREELKPSDIMTIQAFENAIMVHAAIAGSSNSLLHLPAIAHELGIQLS
                     PDLFDKIHRKIPYLLNIRPSGFWPGEYFWYAGGVPAIMEEIKEFLHLDVKTVTGRTLGE
                     NLKDLQLNGFYENCHKYLPALGVKVGDIIKPLHTPIKAQGAIAILKGNLAPEGAVVKHS
                     AISPRLMQVTLKARVFDCEENAIEAVLQKKIHPGEAVFIRYEGPKGSGMPEMFYTTEAI
                     ASDPELVETIALITDGRFSGATRGPAIGHVSPEASEGGPIALVENDDLIRIDIPARRLD
                     IIGTGGIERSAEEIEKILSERRAHWIKPESQYKKGILDIYTHNSVSPMKGAYMEFFM"
     CDS             3465..4493
                     /locus_tag="ctg1_1729"
                     /transl_table=11
                     /translation="MRKNISILVSLLILSLTACSDKGQYFEESGSVFHTSYHIKYKAKQ
                     ILTDKIDSELQRFNLSLNPFNPNSTIAKVNNNEDVEVDEWFTEVFIKAEEISKKSGGAF
                     DITCAPLINLWGFGFSKMDSVTPQMIDSIKAFVGYQKVRLEGKKIIKEDPRILLNCSSI
                     AKGYACDVIARLLEKEGVKNYMVEIGGEVTMKGVNQQGDCWRVGINKPEIGTSGVTNDV
                     EEIVQLCQKGGVATSGDYRNFYIKDGKKYAHTINPATGYPAGQNILSATIVAEDCMTAD
                     AYATTFMVLGVEKAKLLAQSIPKIEYFIIYADNNGQQKVTYSKGMLEYLPNRKTLAILE
                     NP"
     CDS             4502..4879
                     /locus_tag="ctg1_1730"
                     /transl_table=11
                     /translation="MKRYLNQLECKILRAGDSLFNTTTTDNLLIFVFSGKLIIYSQEGT
                     HIAEVAKDHFMLLAQNTNHKVIASAPTRLILIHAGSLSDMIINDPEWNVEKPVVLPIPP
                     ALAHTLNQIEYYMKDKYFTLN"
     CDS             complement(4882..5463)
                     /locus_tag="ctg1_1731"
                     /transl_table=11
                     /translation="MLENLKKYKIVLASNSPRRRNLLSGLDIDFEVRVISDIDESYPDS
                     IDSMEIPLYIARSKAEAYKPTMADDELLITADTIVWTFDGVMGKPANREEAYAMLHALS
                     DHVHQVITGVCIMTKDKNVGFSVESAVCFAKLGDEEINYYLDKYKPYDKAGGYGIQEWI
                     GYIGVEAINGSFYNVMGLPVQKLYQELKHF"
     CDS             complement(5501..6022)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HAD_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1732"
                     /sec_met_domain="HAD_2 (E-value: 1.4e-06, bitscore: 26.4,
                     seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSSINYDLRKIKAFVFDVDGVLSCDVIPLHPNGDPMRTVNIKDGY
                     ALQLAVKKGYEVAIITGGYTEAVQIRFSRLGIQHIYMRSAVKVHDFKDFMEKTGLSPEQ
                     IMYAGDDIPDYEVMTRVGLPVAPADAAPEIKEIAKYISSRRGGEGVARDVIEQTMRAQG
                     HWFGEEAFGW"
     CDS             complement(6015..6782)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1733"
                     /sec_met_domain="F420_oxidored (E-value: 3e-07, bitscore:
                     28.9, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVVFVGAGNLATRLSLEMRKSGMSIGQVYSHTSEHAKILADELG
                     CGWTVVPEDIVEDADLYVFSLKDAVLQDVIARVKPNNGLWVHTAGSMPISVFEGLTARY
                     GVVYPLQTFSKSREVDFKKIPFFLEANSSEDEMVLGEVARALSSDVRFLSSEKRKNLHL
                     AAVFACNFTNHMYALAEKILEEQQIPGEVLLPLIDETAAKVHVMSPVRAQTGPAIRYDE
                     NVINKHMAMLKDPDMRNLYELISRSIHKEARHE"
     CDS             complement(6779..7339)
                     /locus_tag="ctg1_1734"
                     /transl_table=11
                     /translation="MESFATLIQNRRSTRKFTEQLLSPEQVELILKAALMAPASKRSNP
                     WQFVVVEDKEMLKKLAGCKKNGSVFLEGCALAVVVLANVMESDVWIEDASVASIYMQLQ
                     AEDLGLGSCWCQIRNRVTEDEADSNNYVRSLLDIPYQLDVLSIIGIGYKDQVRKPFDES
                     HLQWEKIHIGKFSLPEENKEAEE"
     CDS             7461..9872
                     /locus_tag="ctg1_1735"
                     /transl_table=11
                     /translation="MKIRAIAALLFILISVSAFGEGRIKITGYVRDADGNPLELVNVRV
                     KNTLIGSMTNEKGYYSFSISPGDSISVIYSCLGYNKAERIIPSAQADMRLNVQMNNTSF
                     DLGEVSVTAIRKQTTTMESLNADKIKLLPDPSGGSIESLVVTFAGVSSNNELSSQYSVR
                     GGSYDENIVYVNGIEVFRPLLIRSGQQEGLSFINPDLTEAVNFAAGGFEARYGDKMSSV
                     LDITYKKPKIFEGSASASLLGANAYVGSSIGKFTQVTGFRFKSGRSILGTMDTDAEYDP
                     KFIDLQTYITYQLAPKWEINFLGNLANNNYKFTPYSRETSFGTAEHPKNFKVYFDGRER
                     DRFQTLFGALTLKHNPNENTELGLQASAFKSKEEEGYDIAGEYWLSENGAENPDDDASA
                     AMSVGRYHEHARNRLNATVMNVGHYGMARLLNNTLKWGATVQMEKINDKISEWEKRDSS
                     GYSLPQTGNNVSVYSNLFSDNQIESTRFSAYAQDAFKFRTKQGLFTLVVGVRGSYWTYN
                     KEFLFSPRASLGFIPNFDQDLTLRFATGLYYQSPFYKELRRVDKDKNGNNITVLNKDLK
                     SQRSIHFILGGDYTFRAVDRNFKVTAEMYYKKLDNLNPYTVDNVKIRYYGENCAKGYAM
                     GLDVKFFGEFVPGTDSWISFSLMKAQQTIRETTTVPMANSQGYNISLFFQDYFPGYKRV
                     KLNLKGVLSGGLPQTIPGKGYEAGYFRTPAYKRVDIGLSYQLAGGTDAIMDRGFFRHLK
                     NIWLGLDVFNILDIKNVSSYYWITDVYNVQYAVPNYLTGRQLNVRLIVDF"
     CDS             10001..10411
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1736"
                     /sec_met_domain="Glyoxalase_4 (E-value: 9.3e-25, bitscore:
                     85.0, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MELTHIEHLGIAVKSIEACLPYYEGVLGLKCYNIEVVADQKVKTA
                     FFKVGQTKIELLEPTSEDSTIAKFIEKKGEGIHHIAFAVPDVQAALNEAEEKGVKLIDK
                     APRGGAEGLNIAFLHPKSTCSVLTELCMPGNK"
     CDS             10448..12001
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1737"
                     /sec_met_domain="CT_Btheta (E-value: 3.5e-290, bitscore:
                     960.5, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKVKELIALREQARLGGGEKRIESQHKKGKYTARERIAML
                     LDEGSFEEFDMFVQHRCTNFGIEKTKYLGDGIVTGYGTIDGRLVYIFAQDFTVFGGALS
                     EALAMKICKVMDQAMKMGAPVIGLNDSGGARIQEGVNALAGYAEIFQRNILASGVVPQI
                     SGIFGPCAGGAVYSPALTDFNIMTRGTSYMFLTGPKVVKTVTGEDVTQEQLGGASVHTT
                     KSGVAHFAVDTEEDGLQLIRKLLSFLPQNNLEETPLVECKDPIDRLDDVLNDIIPDNAN
                     QSYDMYEVIGTIVDNNEFLEVHADYAKNIIVGFARFNGQSVGIVANQPKVMAGCLDSNA
                     SRKAGRFVRFCDAFNIPLVTLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKITV
                     TLRKSYGGAYCVMSSKHLRGDMNYAWPTAEIAVMGPSGAVEVIFAKEVAAAEDPKACAA
                     EKEAEYKKAFANPYNAAQYGYIDDVIEPRNTRFRIIRALQQLQTKKLSNPAKKHDNLPL
                     "
     CDS             12023..12916
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1738"
                     /sec_met_domain="OAD_gamma (E-value: 5.6e-11, bitscore:
                     40.9, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MINKKIGVLLLLMVLFSMGAKAQLTTSVKLNEVLVVNEDNFVDDY
                     GKRHPWFELFNNSAGTVDLRGCFLTNDKSNPRKYMIPKGDVLTKVPPRQHLLFWADDQP
                     TKGTFHVNFTFDPNKDNYLALYDSDGTTLIDEVTIPAGQKADVSYGLDLDGVGNWSILD
                     KVTPSTNNLTLDSNAKLENFQRNDPWGIGMTITAMAVVFLGLIILYLVFKQIGNAAIKA
                     SKRNAQKAAGTGAAVSANIGQESGEIFAAIATALYEMSDDNHDIENTVLTIHKVQRSYS
                     PWSSKLYSLRQTPNKK"
     CDS             12940..13371
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 63.7; E-value:
                     3.5e-20)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1739"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.4e-18, bitscore:
                     63.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSFKYTINGNTYKVHINSVVDDVAEVEVNGTPYNVKMEKPAKKQ
                     MVTLKRPAQAPTNASGEPVITRQAAPSVAGAVKSPLPGVILSVDCKVGDTVKRGQKILV
                     LEAMKMENNINADRDGKIVEIKVNKGDSVLEGADLVVIG"
     CDS             13376..14536
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_1740"
                     /sec_met_domain="OAD_beta (E-value: 2.2e-151, bitscore:
                     501.7, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MQESFLQFLGENIQIFLSYTGFANATPGHIVMLLVGLLFIFLAIK
                     YEFEPMLLIPIGFGILIGNIPFKDAGLQLGIYEEGSVLNILYQGVKQGWYPPLIFLGIG
                     AMTDFSALISNPKLMLVGAAAQFGIFGAYIIALQMGFDPSQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPIIQPPFMRLLTTKKERVIRMKPPRAVSQTEKIVFP
                     IVGLLLTAFLVPSGLPLLGMLFFGNLIKESGVTRRLAETARGPLIDVITILLGITVGAS
                     TQATQFLTLNSIKIFGLGALSFVIATCAGVLFVKFFNLFLKEGNKINPLIGNSGVSAVP
                     DAARISQNVGLEYDPSNYLLMHAMGPNVAGVIGSAVAAGILLGFLG"
     CDS             complement(14603..14749)
                     /locus_tag="ctg1_1741"
                     /transl_table=11
                     /translation="MRKKSVNTLLVFGVVVAIILLMIWLFLGTTLVEDTSTEISPVPIE
                     QAN"
     CDS             complement(14818..15534)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_M22"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1742"
                     /sec_met_domain="Peptidase_M22 (E-value: 1.6e-25, bitscore:
                     88.3, seeds: 111, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSLILNIETSTSVCSVALSEGEEVVFEKASFEGPSHAALLGVYME
                     EALEAAKSKGIKLDAVAVSSGPGSYTGLRIGVSVAKGLCFGYGIPLIGIHTLDILASAA
                     IRKNKEEADCLYCAMLDARRMEVYSSIYDSHLNTIRATTADIVDADSYASFLENGKVCF
                     FGDGAAKCETVITSPNACFMAGIYPLAVNMASLSQKAYDDGRFENVAYFEPFYLKEFQA
                     TIAKNKVLNEALGKNK"
     CDS             15736..16596
                     /locus_tag="ctg1_1743"
                     /transl_table=11
                     /translation="MTGFGKVTAELPSKKVTVEIKALNSKQLDLSTRIPSIYKDKEMEL
                     RSLLLQSLERGKVEFNIFIEYIGKDTPTQINLAAVENYYNQIKEIAEKLNISVPNDWFQ
                     TLLRMPDAIKSETVEPDESEWEVVLETVKDAIKHLCDFRIQEGAMLQKLFEQKIANIAT
                     LLKEVEKYEGERIEKIKARIMDNLQKIAEKDYDKNRFEQEMIYYIEKLDVNEEKNRLDN
                     HLKYFISTMESGHGQGKKLGFIAQEMGREINTLGSKSNHAEMQKIVVQMKDELEQIKEQ
                     VLNVL"
     CDS             16611..17177
                     /locus_tag="ctg1_1744"
                     /transl_table=11
                     /translation="MAGKLIIFSAPSGSGKSTIINYLLKQDLHLRFSISATSRAPRGTE
                     KNGVEYYFLTPEEFRSRIANGDFLEYEEVYTDKYYGTLKSEVERILNEGDNVIFDVDVV
                     GGCNIKKFYGDRALSVFIQPPCIDDLRKRLEGRGTDSPEVIESRIAKAEYELGFTGQFD
                     KVVVNDDLETAQKDALKIIREFLNK"
     CDS             17181..17360
                     /locus_tag="ctg1_1745"
                     /transl_table=11
                     /translation="MSNIFKNTRFMMGLSIVCGIASLVLGGISLYYKEYIIGGALIFNI
                     FICFINYKGWQKKG"
     CDS             17372..17938
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) CTP_transf_like"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_1746"
                     /sec_met_domain="CTP_transf_like (E-value: 3.9e-22,
                     bitscore: 76.9, seeds: 65, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGLKTGIYSGSFNPIHIGHLALANWLCEFEGLDEVWFVVTPHNPL
                     KKKDDLLDDSLRLEMAQAAIDGYSKFRVCDIEFYLPKPSYSIDTLRTLSRNYPNRDFYF
                     IMGADNWQLFPRWKEHEKILQDYKLLIYPRLGFDISIPAIYPNVKKVDAPLMEISSTFI
                     RNAYQADKDIRFFLPEGVRPYYYKI"
     CDS             18068..18217
                     /locus_tag="ctg1_1747"
                     /transl_table=11
                     /translation="MSVLTMPKFTSQILLLFSKVLHILENLLLKNFTGLKVSMSCFSKL
                     HVNR"
     CDS             complement(18280..18402)
                     /locus_tag="ctg1_1748"
                     /transl_table=11
                     /translation="MCNALMFTNKIKKNIKNKKNGALCVLFNVFYLFNCIGYKN"
     CDS             18430..18642
                     /locus_tag="ctg1_1749"
                     /transl_table=11
                     /translation="MDKLKKLTKVVLNQQGKVLPKEQMMKILGGGSAYCHCWNSSGSFE
                     ASSCSECDSKCNGLGGVQNCNTIGG"
     CDS             18717..19835
                     /locus_tag="ctg1_1750"
                     /transl_table=11
                     /translation="MIYLLFLVALLLICCNPDQAKDNSKDETIEYFIPLSHRVEKDVDE
                     MFEEYRYVPLETRDDALIDVLYKIRNIALFQEDIYIGSDDILIAYDKSGKIKRVLSKKG
                     EDPQSYFFLGNFTIWPNGDILISSSGDVTTYSNSFKFIRKWSDHENIGLIEAIILFNDS
                     SYIIKCTPTERQLRYRIINHKNGTYISTYDSIEKQNKYISSFTNSFERFEGLIISHGYQ
                     GNEILECTMDSTKVRYRINIDNKIPPAGFWAQDGKDYVQIVMEEAEKGYIGHIPDYVES
                     KETILLSFKGKRDDLEGVALIDKKDGNARVLENIKFDDNFRWLPKQFFSLDEGWCAMLM
                     YPEDVLKKEEFARRFPGLNEESNPVLFIGKLR"
     CDS             19855..21402
                     /locus_tag="ctg1_1751"
                     /transl_table=11
                     /translation="MEHDNLFIQILEILSIKYTKDFTLRFYEKHPHKNSLFGLSEMLRY
                     YKIENVAAEIQKTQECLSSLDVPFVAYVDHEFVLVRHVSTEAIIYSWRGKNITLSIPVF
                     LERWSGIVLLFESTDESIEPDYKEHRKEYLRQRIVIACFVSLLLSLIGCALITNRGMEI
                     GIWGLWGVNVIGASFCGILLSREILGSDKYVNKICSLFLKSSDCNGTLDSQASHFLGIS
                     WSVFGLGYFLSAILFIALLPQYVIYAETLNIIALPYTAWSVWYQKFRVKQWCALCLSVQ
                     ATVWITFLISLFAIGMDFNQWDLFDFTTIGCVYGLVILSLHFTVTLYVKEKQIQRSNNK
                     LSSIKLNASVFKSLLNEQPQYDIDKNTGILLGNRDAKEWITIISNPHCAPCAKLHLQIE
                     KLLKEYKEEICIQIILTSFSKELEPSAMLLTSMYLLNNESDYLRFLSDWYAKGRHKKED
                     CYKRYRLNPNDKDMLANFQAQNEWVRRNTISSTPTVLTNGYLLPEEYELKDMSYLIN"
     CDS             21408..22451
                     /locus_tag="ctg1_1752"
                     /transl_table=11
                     /translation="MNKLASQIDSLNKHLIGSLHTSYPFGLAHGKMGLLIYLYHLYDYT
                     QEAIYKEKAERLLDDLLENDLSKNAELTVEEGLCGVALGLDYIVKKQFVDGDINDLLSG
                     IDDLLFKKLVFGNMESRYSLSQLIHFLYYIYKRLEIQTNDNERFPFEGLAIKLVNQLAD
                     LIDASFFEESYTFSIYQYHVPILMKTLSCLIQYDFYKDRIQKVLEQLSLYMFSHLPHLH
                     LNRLYLLWGMLPLRVCSPDWQRYVDELRKSINLDIIYNREIKGRDIYISNGYASLYFLL
                     EGLKRDFPEYTIPFNPHLIYDRIISSDAWDALMENEYYYNIHRGLLNGFPGTVLALLNI
                     KQRYLCE"
     CDS             22442..23233
                     /locus_tag="ctg1_1753"
                     /transl_table=11
                     /translation="MRIDLTDTTFIIPVRIDSMIRLENLLMSVDSIVRYFRTRILILEA
                     SSYQNEIIPSLIKDDTVKYTFLVDKDPVFYKTKYLNILAKQVDTPLVCIWDADVILDHL
                     QILDAVKQLRTRTSDVAYPYDGNFLDTSDILREHYWLHRDLDFLKKHQAKMNSLYTVEG
                     VIGAVGGAVFAQTEKYLQAGMENEDFYGWGLEDGERHYRWLSFGYRIYRSEGCLFHLSH
                     PRDQNGMFRSRIHSEKAMHDMNEVVNYSKEELREKFSLDSR"
ORIGIN
        1 aaagatatga cccgttgtct aagacgatcc ccacgaaatt attcaacgcg acagctcgta
       61 aattctcggg aataaagaac ttacacgatt tcaattgcgg attgaaagcg tataagaatg
      121 ttgtcattaa aaatatagag gtgtataacg atatgcaccg ttacatacct tatttagcta
      181 agattgccgg atttcacaag attggcgaga aagtagtgaa acatcaagcc cgcaagtacg
      241 gaaccactaa attcgggttg gatcgcttcg tgaacggtta tcttgatttg atcacgcttt
      301 ggtttacttc caaattcgga aagaaaccga tgcacttctt cggtttatgg ggaagcgcta
      361 tgttcttcat tggttttatc gctctagtaa tcgtactcag catgaaattg atctcgatgt
      421 actctggaga tctaagacct ttggttacaa gttcccctta tttctatatt tcattgacag
      481 cgatgattct gggaacccag atgttcctag cgggctttat cggggagttg atttcccgca
      541 attctccgaa tcgcaataac tataaaatag aggatgagat atgagtttcc tagaattagc
      601 gagaaaacgt tgttctatcc gaaagtatgc ccccaaaaat gtggagcaag aaaagattga
      661 ttatatccta gaagcagctc gtttggcccc ttcggcggta aattatcaac cttggtattt
      721 tgtatgggtt caaagcgcgg aaggaaaagc taaattacaa gaatgctatc cccgggaatg
      781 gttcaagcaa gcgccttatt acttgatcgt ttgcggagat catcagcaat cttggaaacg
      841 gggcgatcat aaggatcata tggatatcga tacggctatc gccacggaac acatttgttt
      901 agccgctgcc gaacaaggat tgggtacttg ttgggtttgc aatttcgaca cggagctttg
      961 ccgtaaacat tttaaaattc cggaaacgat cgagcctgtt gtactgatac cgttcggcta
     1021 tccttccgac ccggcattat tcgatgagac tccaaagaaa cgtaagccca tagaagaaat
     1081 tattaaacgg gaatcattct agtatgttat acattgaagt tctgctacta gcgatcggct
     1141 tatccatgga tagcctagca gtatcagtta ccggcggcgc agttcttaag aacaactgca
     1201 ccgccggtaa tattattaag atagcgagcg tgctcggtat attccaagcc ggaatgaccg
     1261 tgattggtta tacgatggga ttaggattcg aaaaatacat ttgcgccttc gatcattgga
     1321 tcgcatttac cctcttgctt tacttaggtg gaaaaatgat atacgatagc acgaaggaag
     1381 aggaggaaga cgggaaattc gatcctctat gtaaccggac attatgcgga ttgggaatag
     1441 cgacaagtat cgatgccctc gccgtaggaa tctctctggc gatcttaaaa tcaccgctct
     1501 tgctgcaagc ctcgactatc ggtgttgtca ccttcgctat ctctgccttc ggtgtctatt
     1561 tcggtaaccg attcggcaag agaatcgact tgaagctgga cctcatcgga ggtttaatct
     1621 taatcggtat cggtacaaag attttgatag agcatgtatt ctttagctag ggatacctta
     1681 ttgaataaat aaccttatac attaattaat agacatgaaa agccagcaat tacgaaaatt
     1741 agcgccggag ctggattcac tccggctagg cagcggttgg aaaatcgacg aattgagtaa
     1801 accgcaaatc attgtagaaa gcagttacgg acatagccat ccgggaagcg cccatctgga
     1861 taaattggtg gacgaggccg gaatcggtat aaaggaaaag gggggacgtg ccgcaaacta
     1921 cttcgtcact gatatttgtg atggagaggc gcagggacac gatggtatga actactcatt
     1981 agtctcccgt gatatcatgg ccgccatgat ggaaattcat gtaaaagcga ctcctttcga
     2041 cgctggtgtc tttatagcca gttgcgacaa atccgtccct gcgcatttga tggcgatagc
     2101 ccggctagat atgcctgcta tattcatgcc cggtggtata atgaaagccg gtcccaacct
     2161 actcacgtta gaacaaatcg gtacctatag cgcccaatac gagcgaaagg aaataacgga
     2221 agaacaattc atggtttata agcgtgacgc atgtccggat tgtggagctt gttctttcat
     2281 gggcactgcc tctacgatgc aagtaatggc agaagcgcta ggcatcgctt taccgggttc
     2341 cgccttgatc cccgcccatt tacccgagtt aaaagaaacc gcccgtaaag ccggagaaca
     2401 tgcgctcgga ctggcgagag aagagttaaa accctccgat atcatgacga tacaagcgtt
     2461 tgaaaatgcg atcatggtac atgccgccat agcgggttcc agcaacagcc tgcttcatct
     2521 tccagctatc gcccatgaac tgggaatcca gttatcaccg gatttgttcg acaagataca
     2581 tcgtaagatc ccctaccttt taaatatacg tcccagcggt ttttggcccg gcgaatactt
     2641 ctggtatgcg ggaggcgtac cggcgatcat ggaagaaatc aaggaattcc tccatctcga
     2701 tgtcaagacc gttaccggca gaacattggg agaaaactta aaagatttac agctcaacgg
     2761 cttctatgag aattgccata aatatcttcc tgccctagga gtaaaggttg gcgatattat
     2821 caaacctctt catacaccga tcaaggcaca aggagccatc gctatattga aaggaaattt
     2881 agcgcccgaa ggggcagtcg taaaacattc ggcgatttca ccccgcttga tgcaagtcac
     2941 cctgaaagcg agggtattcg attgtgagga gaacgctatt gaggcggtat tacaaaagaa
     3001 aatccatccg ggagaagcgg tatttatccg ttatgaagga ccgaaaggaa gtggaatgcc
     3061 agaaatgttt tatacgacag aagcgatcgc ctccgatcct gagttggtag agaccatcgc
     3121 attgatcacc gacggtcgtt tctccggagc gacccgaggc ccggcgatcg gacatgtatc
     3181 cccggaggct tccgaggggg gaccgatcgc cttggtagag aacgatgact tgatccgtat
     3241 cgatattcca gcgagaagat tggatataat cggtaccggc ggtatcgaga gaagcgcgga
     3301 agaaatagaa aagatcctat ccgaaaggcg tgcacattgg ataaaaccag agtcacaata
     3361 taaaaaagga atccttgata tttatacaca caatagcgtc tcccccatga aaggggcata
     3421 tatggaattt tttatgtaag ttcgcgacat aaaatttcat aatgatgcgc aagaatattt
     3481 ccatattagt cagcctgttg atcttatcgc ttacggcttg ctcggacaag ggccaatatt
     3541 tcgaagagag tggttctgtt tttcatacaa gttaccacat caaatacaag gccaagcaaa
     3601 tcctaaccga taagatcgac agcgagctgc aacgttttaa cctctcctta aatcctttca
     3661 accccaactc cacgatcgct aaagtcaata ataacgagga tgtggaggta gatgaatggt
     3721 ttaccgaagt attcattaag gcggaagaaa tctccaaaaa atcaggagga gcttttgata
     3781 ttacttgcgc tccattaatt aatctatggg gattcggatt cagtaagatg gacagcgtaa
     3841 ccccgcagat gatcgatagc atcaaggctt tcgtcggtta tcaaaaagta agattggaag
     3901 gaaagaaaat catcaaagaa gatccccgga ttctattgaa ttgttcgtcc atcgcaaaag
     3961 gttatgcttg cgatgttatc gcccgcctgc tggaaaagga aggcgtaaag aactacatgg
     4021 tagaaatagg tggtgaggtc accatgaaag gcgtaaatca acaaggtgac tgttggcgag
     4081 tcggcatcaa caagccggaa atagggacaa gtggcgtaac aaatgatgtt gaagagatcg
     4141 tacaattatg ccaaaaaggg ggtgtggcta cttctggtga ctaccgaaac ttctacatca
     4201 aggatggtaa gaaatatgcc catacgatca atccggcgac cggttatccc gctggacaaa
     4261 atatccttag tgcgacaatc gtggcggaag attgtatgac agcagacgct tacgctacga
     4321 ctttcatggt tttgggagtc gagaaagcga agctactggc acaatccatc cccaaaatag
     4381 agtatttcat tatttatgcg gacaacaacg gacaacagaa agtcacctac tcaaaaggta
     4441 tgttggaata ccttcctaac agaaaaacat tggctatcct cgaaaatcct taagttccta
     4501 catgaagcgt tatctaaatc aacttgaatg caaaatactg agagccggag attccctgtt
     4561 taataccaca accacggata acctattaat cttcgtattt tcgggaaaac ttattattta
     4621 cagccaagaa gggacacata tagcggaagt ggcaaaagat catttcatgc tacttgcgca
     4681 aaacaccaat cataaggtta tagcctcagc ccctacccgc cttatcttaa tacatgcggg
     4741 cagtctatcc gacatgatca taaatgaccc ggaatggaat gtggagaaac cggtcgtctt
     4801 accgattccc ccagccttag cgcacacatt aaatcagata gaatattata tgaaggataa
     4861 atactttacc ttgaattgag attaaaaatg tttcaattcc tgataaagct tttgcacagg
     4921 taatcccatc acgttataaa aactaccatt gatagcctct accccgatat aaccgatcca
     4981 ctcctgaatg ccataccctc ccgctttatc ataaggttta tatttatcca aataataatt
     5041 aatctcttca tcacccaatt tagcgaaaca aaccgcagat tcgacggaaa agcctacatt
     5101 tttgtccttt gtcatgatac aaacaccggt tattacctga tgtacatgat ccgacaaagc
     5161 atgaagcata gcataagctt cctctcgatt cgcaggcttt cccataaccc cgtcaaacgt
     5221 ccaaacgatc gtatctgccg tgattagcaa ttcatcatcc gccatagtcg gtttataggc
     5281 ctccgctttc gaacgggcaa tatataaagg gatctccatg gagtcaatag aatccgggta
     5341 agactcgtca atatccgaaa ttaccctcac ctcgaagtcg atatccagac cagataacaa
     5401 attccgtcgt ctcggagaat tagaggctaa gacgatcttg tactttttta aattctctaa
     5461 cataacctat tcgattaagc gttacacatt caccaaaatt ttaccaccca aaagcctcct
     5521 cgccgaacca gtgtccttgc gcccgcatcg tttgctcgat cacgtcccta gctacgcctt
     5581 cgccacctcg ccgggaggat atatatttcg ctatctcctt gatttccgga gccgcatccg
     5641 caggtgccac cggcaatccg actcgcgtca ttacctcata atcaggaata tcatcacccg
     5701 catacatgat ttgctcagga gacaagcccg ttttttccat aaaatcctta aagtcatgca
     5761 cctttacagc gctacgcata taaatatgtt gtattcctaa acgagaaaag cgaatctgta
     5821 cggcttccgt atatccgccc gtaattatag cgacctcata acctttcttc acggccaatt
     5881 gcaaggcata gccatccttg atattgacag tacgcatcgg atcgccattc gggtgaagcg
     5941 gaatcacatc gcaggatagc accccgtcta catcaaagac aaaagccttt atttttctca
     6001 aatcatagtt tatactactc atgtcgagcc tccttatgta tacttcggct aatcagctca
     6061 tatagatttc gcatatccgg atctttaagc atagccatat gtttgtttat cacattctcg
     6121 tcatatcgta tagctggtcc cgtttgggct cgcaccggcg acattacatg taccttagcg
     6181 gctgtctcgt ctatcaaagg tagcaagacc tctcccggta tttgctgttc ttccaagatc
     6241 ttttcagcta gcgcatacat atgattcgta aaattacaag cgaaaaccgc cgctaaatgt
     6301 aagttctttc gcttctcgga ggagaggaaa cggacatcac tggagagcgc cctagccacc
     6361 tctcccagca ccatctcatc ttcagacgag ttcgcctcta aaaagaacgg tattttcttg
     6421 aaatccacct ccctactctt actaaacgtt tgtaacggat aaaccacccc atatctagcc
     6481 gtaagacctt caaatacaga gattggcata ctccctgccg tgtgcaccca caaaccgtta
     6541 ttcggtttta cacgggcgat aacatcttgg agcacggcat ctttcaaaga gaaaacatac
     6601 aagtcggcat cttccacaat atcttccggg acaacagtcc acccacatcc caattcatcg
     6661 gctaaaatct tagcatgctc acttgtgtga ctatacactt gcccgatact cattccggac
     6721 ttacgcattt ccaacgaaag ccgggtagct aagtttccgg caccaacaaa tacgactctc
     6781 attcttccgc ctctttattt tcttccggaa gagagaactt tcctatatgt atcttctccc
     6841 attgtaaatg ggattcatca aaaggcttac gaacctgatc cttataaccg ataccaatga
     6901 tagacaagac atccaattga taaggaatat ccagcaacga acgaacataa ttattcgaat
     6961 ccgcctcatc ctctgttacc cggttccgga tctgacacca gcaactgccc aatcccaaat
     7021 cctctgcttg caattgcata taaatagaag cgaccgaagc gtcctcgatc caaacatcgc
     7081 tttccatcac attcgccaag acaaccacgg ccaaggcaca cccctccaga aaaacagaac
     7141 catttttctt acacccggca agtttcttca acatttcctt atcttccacg accacgaact
     7201 gccaaggatt actacgtttt gaggccggag ccatcaacgc cgccttcaag atcagttcta
     7261 cctgctcggg tgaaagtagt tgttcggtaa acttacgtgt acttcttcta ttttgtataa
     7321 gtgttgcaaa actctccatt tttttcgttc tttgtactct tttaatatta agattcgcaa
     7381 atataaatat aattttttgc acccatatat acgtatcgtt cttttttctc gttagtattt
     7441 ttataattga acaatagatt atgaagattc gtgcgatagc cgcgctgcta tttatactta
     7501 tttccgtgag tgcctttggc gagggccgca taaaaatcac tggttatgtc cgtgacgccg
     7561 acggtaaccc cctggaatta gtgaatgtcc gggttaagaa cacgttgatc ggctccatga
     7621 ccaacgagaa gggatattat tccttttcca tatcgccggg ggattctatc tccgttattt
     7681 actcttgtct gggatataat aaggcagagc gtatcattcc ctcggcacaa gcggatatgc
     7741 gcctgaacgt acagatgaac aatacctcat ttgatttagg ggaagtatcc gttactgcca
     7801 tccgcaagca gaccacgacc atggagtccc taaacgcgga caaaatcaag ttattgcccg
     7861 atccctccgg aggtagtata gagagcttgg tcgttacgtt tgccggagta tcgtccaata
     7921 acgagttaag ttcccagtat tccgtacgtg gaggtagtta tgatgaaaat atcgtttatg
     7981 tgaatgggat cgaggtattc cgtccacttc tgattcgctc gggacaacaa gagggcctta
     8041 gctttatcaa tccggaccta acggaggcgg tcaatttcgc cgccggtggc ttcgaggctc
     8101 gttacggaga caagatgagt tccgtgctgg atattaccta taaaaagcct aagatattcg
     8161 aaggctcggc ttccgcgagc ttgttgggcg cgaatgctta tgtaggcagt tctatcggta
     8221 aatttaccca agtaacgggt ttccgcttta aaagcggtcg gtctattttg ggtaccatgg
     8281 atacagacgc agaatacgac cctaaattta tcgatctgca aacttacatc acgtaccaat
     8341 tggcccctaa atgggaaatc aatttcttgg gaaacctcgc taacaataat tataaattca
     8401 ccccttatag ccgggaaacc tctttcggta cagccgagca tcccaagaac ttcaaagtct
     8461 atttcgacgg aagggaaaga gaccgtttcc aaaccttatt cggtgcgctt acattgaaac
     8521 acaaccccaa tgagaacaca gagttgggac ttcaagcctc cgctttcaaa agcaaggaag
     8581 aagagggata cgatatcgcc ggagaatatt ggctaagcga gaacggagcg gaaaatccgg
     8641 atgacgacgc gtcagccgcc atgtccgtag gccgttatca cgagcacgca cgaaaccgtt
     8701 tgaacgccac cgtcatgaat gtcgggcact atgggatggc ccgcctttta aacaatacgt
     8761 tgaaatgggg agccacggta caaatggaga aaatcaatga taagatcagt gaatgggaaa
     8821 aaagggattc ctcaggttat tctttgcccc aaaccggtaa taacgtaagt gtatattcga
     8881 acctcttttc tgataatcag atagaaagca cacgcttttc cgcttatgcg caagacgcgt
     8941 tcaaattcag gaccaagcaa ggtctgttca cgttagtcgt aggggttaga ggtagttatt
     9001 ggacttataa taaggagttc cttttcagtc cccgtgcctc attgggcttt atcccgaact
     9061 tcgaccaaga cttgacgctc cgtttcgcca ccggactgta ttatcaatcg cccttctaca
     9121 aggaattacg tagagtagac aaagataaga acggcaataa tatcacggta ttgaacaaag
     9181 atctaaagtc acaacgctcc atccatttca tcttgggagg agattatacg ttccgtgccg
     9241 tagaccggaa tttcaaggtg accgccgaga tgtactataa aaagctggac aatctgaatc
     9301 cctacaccgt agataacgtc aagatccgct attacggcga gaattgcgcc aaaggttacg
     9361 ccatgggact cgatgtcaaa ttcttcggag aattcgtacc gggtaccgac tcatggatca
     9421 gcttctcctt gatgaaagcc cagcaaacca tccgggaaac aacgaccgtt cctatggcca
     9481 atagccaagg ctacaacatc tcactcttct tccaagatta tttcccgggc tataaacgag
     9541 tcaagctaaa tctgaaagga gttctatccg gaggacttcc ccagacaatc ccgggcaaag
     9601 gatacgaagc cggctatttc cgtacgcccg cctacaaacg tgtagatatc ggcctctcct
     9661 accaattggc aggaggcacg gacgctatca tggacagggg cttcttccgc catttgaaaa
     9721 acatttggct aggtctggat gtatttaaca tattagacat caaaaacgtt agttcctatt
     9781 attggataac agatgtatat aatgtccaat acgcagttcc aaactatctg accggacgtc
     9841 aattgaacgt tcgtctgatt gtcgattttt aataaaatgt atctttaaac acatttactg
     9901 ggagataaaa acaaaaaatt atttcctcat tcataaaaag tagtgtacat ttgcacacaa
     9961 tagaaacaaa catttactaa atctttaaat tattattgac atggaactta cacatatcga
    10021 acatttaggt atcgcagtga agagtatcga ggcttgttta ccctattatg aaggcgttct
    10081 tggattaaaa tgctacaata tcgaagtagt agcagaccaa aaagtaaaaa ccgcattttt
    10141 caaggtagga cagactaaga ttgaattact agagccgacc agcgaagata gcacgattgc
    10201 gaaatttatc gagaaaaaag gtgaaggtat ccaccatatc gcatttgcgg tacctgatgt
    10261 acaggcagct ttgaacgagg ctgaggaaaa aggcgttaaa ttaatcgata aagctccccg
    10321 tggtggcgcg gaaggcttga acatcgcttt ccttcacccg aaatcaactt gcagcgtatt
    10381 gacagaactt tgcatgccgg gcaacaaata attaatccgt tcatttctaa caacaaatca
    10441 aaatacaatg agtaaccagc ttgaaaaagt aaaagagctc atcgcacttc gtgagcaagc
    10501 tcgtttgggt ggaggagaga aaagaatcga atcacagcac aaaaaaggca aatataccgc
    10561 tcgtgagcgt atcgccatgt tgcttgacga aggtagtttc gaggaattcg acatgtttgt
    10621 tcaacaccgt tgtacaaact tcggtatcga gaaaactaaa tatttaggcg atggtatcgt
    10681 aacaggttat ggtacgatcg acggacgttt ggtatatatc ttcgctcaag atttcaccgt
    10741 attcggtgga gccttgtctg aggctttggc tatgaagatc tgtaaagtaa tggatcaagc
    10801 catgaagatg ggcgctcccg ttatcggttt gaacgactcc ggtggagctc gtatccaaga
    10861 aggtgtaaac gccttggcag gatacgcaga gattttccaa cgtaacatct tggcatctgg
    10921 tgttgttccc cagatttccg gtatcttcgg cccttgcgcc ggtggagccg tttattctcc
    10981 ggctttgaca gacttcaaca tcatgacacg tggtaccagc tacatgttct tgacaggtcc
    11041 gaaagtagta aaaaccgtaa caggtgagga tgtaacccaa gagcagttgg gtggagccag
    11101 cgtacacacc acgaaatcgg gtgtagccca tttcgctgtc gatacagaag aggatggttt
    11161 gcaattgatc cgtaaattgc tcagtttctt accacagaac aacttggaag aaactccgtt
    11221 agttgagtgc aaagacccga tcgatcgtct ggatgatgta ttgaatgata tcattcccga
    11281 taacgctaac caatcttacg atatgtacga ggttatcggt acgatcgtcg ataacaacga
    11341 gttcctagag gtccatgcgg actacgctaa gaatatcatc gtaggtttcg ctcgtttcaa
    11401 cggacaatct gtcggtatcg tagccaacca gccgaaggtt atggcaggat gcttggatag
    11461 caacgcatct cgtaaagcag gtcgcttcgt tcgtttctgc gacgctttca atattccttt
    11521 ggtaacattg gttgacgttc cgggattcct tccgggtaca ggtcaggaat acaacggtgt
    11581 aatccttcat ggcgctaaat tgctttacgc ttatggtgag gctaccgttc ctaagattac
    11641 cgttacattg cgtaagtctt acggtggagc ttattgcgtg atgagttcta aacatttacg
    11701 tggtgatatg aattacgcat ggccgacagc cgagatcgcc gttatgggcc cgagcggtgc
    11761 cgtagaggtt atcttcgcca aggaagtagc agccgctgaa gatccgaaag catgcgcagc
    11821 agagaaagaa gctgaatata agaaagcatt cgctaatcct tataacgcag ctcaatacgg
    11881 ttatatcgac gatgttatcg aaccgcgtaa cactcgtttc cgtattattc gtgctttgca
    11941 gcaattgcag actaagaagt taagcaatcc tgctaagaaa catgataacc tgcctctata
    12001 atccgtaaaa caggagatga atatgataaa taagaaaata ggggtattgc tactgttaat
    12061 ggttctcttc agtatgggag ccaaggcaca gttgactacc tccgttaaat taaatgaagt
    12121 gctagttgtc aatgaagata actttgttga tgactatgga aaacgccatc catggtttga
    12181 gttatttaat aactcagcag gtacggtgga tttacgagga tgcttcttaa cgaacgataa
    12241 aagtaatccc agaaaatata tgatcccgaa gggagatgta cttaccaaag ttcctccccg
    12301 ccagcatctt cttttttggg cagatgatca gccaacaaaa ggaacatttc atgtaaactt
    12361 cacattcgat ccaaacaaag ataattatct agccttatat gattcagatg gtacaacttt
    12421 gatcgacgag gtgacaatcc ctgccgggca aaaagcagat gttagttacg gtctggatct
    12481 tgatggagta ggaaattgga gtatccttga caaagtgact cctagcacca ataatctgac
    12541 gttagattcg aatgcgaaac ttgagaactt ccaacggaac gacccatggg gtattggtat
    12601 gaccataaca gccatggcag tcgtattcct tggcttaatc attttgtatc tagtattcaa
    12661 gcagatcggt aacgcagcga tcaaagctag caagcgtaac gctcaaaaag ccgcaggaac
    12721 aggtgctgcc gtatcagcca atatcggtca agaatcaggt gaaatttttg ccgctatcgc
    12781 taccgctctt tatgagatga gcgatgacaa ccacgatatc gagaacacgg tattgactat
    12841 ccacaaggtt caacgcagct attcaccatg gagttctaag ctttattctc tgcgtcagac
    12901 tccaaataaa aagtaatcat cctaaaatcc aattgacgaa tgaaaagttt taaatatacc
    12961 attaacggta acacatataa agtacatatc aactcagttg tagatgatgt ggcagaggta
    13021 gaggtaaacg gaacccctta taacgtaaaa atggagaaac ctgcgaaaaa acaaatggtt
    13081 acattgaaac gtccggctca agctccgacc aatgccagcg gtgaacctgt tatcacccgt
    13141 caagcagctc caagtgtagc cggcgctgtt aaatctccgc tgccaggtgt aattttaagt
    13201 gtagactgta aagtcggcga tacagttaag agaggccaaa agatcttggt attggaagcc
    13261 atgaagatgg aaaacaacat caatgccgat cgtgacggta aaattgtaga aattaaagta
    13321 aacaaaggcg actctgtatt ggaaggtgca gatctcgttg taatcggtta atgatatgca
    13381 agaaagtttc ttacaattcc taggagaaaa tatccaaata tttctctcct atacaggatt
    13441 tgcgaacgcg actccagggc atatcgtgat gctattggta ggtttgctgt tcatattcct
    13501 agcgattaaa tatgaattcg agccaatgct tctgatccct attggtttcg gtatcttgat
    13561 cggaaatatc cctttcaagg atgccggatt acaattaggt atatacgaag agggttctgt
    13621 attgaacatt ttataccaag gagtgaaaca aggttggtat ccccccttga tattcctcgg
    13681 tatcggtgcc atgacagact tctccgcttt gatatccaat cctaagttaa tgctagtcgg
    13741 agctgccgcc caatttggta ttttcggtgc ttatatcatt gcattgcaaa tgggatttga
    13801 cccgagccaa gccggtgcta tcggtattat cggaggagct gatggtccaa ccgcaatctt
    13861 cttgtcatcc aagttagctc ctaacttgat gggtgctatc gctgtatccg catactcata
    13921 tatggcattg gttcctatta tccagccacc gtttatgaga ttgcttacaa cgaagaaaga
    13981 acgtgtgata cgtatgaaac ctccaagagc cgtttcacag acggagaaaa tcgttttccc
    14041 gatcgttggc ttgctattga cagccttctt ggtaccgtct ggtttgccat tgttaggaat
    14101 gttgttcttc ggtaacttga tcaaggaaag tggtgttact cgccgtttgg cagagacagc
    14161 ccgcggcccg ctgatcgatg ttattacgat cttgttaggc atcacggtag gtgcttctac
    14221 acaagctacc cagttcttaa cattgaactc tatcaagatt ttcggtttgg gtgcgttgtc
    14281 attcgttatc gctacttgtg ccggtgtatt gttcgttaag ttctttaacc tgttcttgaa
    14341 agaaggcaac aagatcaatc cgttgatcgg taactccggt gtatccgccg tacctgacgc
    14401 tgcccgtatt tcccagaacg taggtttgga atacgatcca agcaactact tgttgatgca
    14461 cgctatgggt ccgaacgtag caggtgtaat cggttccgct gtagctgccg gtatcttgct
    14521 aggattcctt ggttaataaa acaactatct atattaaaaa aggcgaggtc cgaaaggatc
    14581 ccgccttttt atgttattgt tctcagttag cttgctctat aggaaccgga ctaatctccg
    14641 tactcgtatc ctccaccaac gttgtcccga ggaacaacca gatcatcaaa aggattatag
    14701 cgacaaccac accaaatacc aatagcgtat tcacactttt ctttctcatg tctttaactg
    14761 atttattcat tttagaataa acagccggaa catgaatttg gttgtgtacc cttactctta
    14821 tttgtttttc cctaacgcct cgttcagcac tttgttctta gcgatcgttg cttggaattc
    14881 tttcaaatag aaaggctcaa aataagccac attctcaaaa cggccatcat catatgcttt
    14941 ctgcgacaag gatgccatat ttacagccaa tggatagata ccagccataa aacaggcgtt
    15001 cggagaagtg attaccgtct cacatttagc ggcaccgtct ccaaagaaac aaaccttacc
    15061 gttctctaaa aaagaagcat acgaatcagc atctacgata tcagcagtcg tggcacgtat
    15121 cgtgttgaga tgggaatcat aaatcgaaga gtagacttcc atacgacggg catccaacat
    15181 agcgcaatac aagcaatcgg cctcctcctt atttttccgg atagcggcag acgctaaaat
    15241 atccagcgta tgaataccga tcaaaggaat accataccca aagcataatc ctttagccac
    15301 agacaccccg atgcgtaacc ccgtataaga tccgggtccg ctacttaccg ccacggcatc
    15361 cagttttatc cctttcgact tcgcggcttc taatgcctct tccatataaa cgcccaataa
    15421 cgccgcatga gacggcccct caaaggaagc cttctcaaag accacctcct ccccttccga
    15481 cagggctact gaacatacgg aagtggatgt ctcgatattt aagatcaatg acataataat
    15541 taactattaa caattgataa ttgaacgaac aaacaatctc aatccttcaa tctgattagg
    15601 ctgcgaaggt atacaaaaat tcattatact atcaaggcag ccctatgaga aacatctatt
    15661 tatgagaaaa taaacatcaa atctaaaagg aaaccactat ctttgcgcaa acttttgaga
    15721 aaaatgatac aatcaatgac tgggttcggt aaggttacag ccgagctccc ttcaaaaaaa
    15781 gtaaccgtag agataaaggc tttaaacagt aagcaattgg atttgtccac ccgtatccct
    15841 tccatataca aggataagga aatggagctt cggagcctgt tacttcaatc tttggagcgg
    15901 ggaaaagttg agttcaatat ctttatagaa tatataggca aagatactcc tacacagatc
    15961 aatcttgccg ccgtagagaa ttattacaac caaatcaagg agatcgcaga gaaactgaat
    16021 atcagcgttc cgaacgattg gttccagacc ttgctccgga tgccggacgc aatcaagtct
    16081 gagaccgtag aaccggacga atccgaatgg gaggtggttt tagaaacggt aaaggacgct
    16141 atcaagcacc tgtgtgattt ccgtatccaa gaaggagcca tgcttcaaaa gcttttcgag
    16201 caaaagatag ccaatatcgc cactctgttg aaagaagtgg agaaatacga gggggaacgt
    16261 atcgagaaga tcaaggctcg tatcatggat aacctgcaaa agatagccga gaaggattac
    16321 gacaagaatc gcttcgagca ggagatgatc tattacatcg agaagctgga tgtcaacgag
    16381 gaaaagaacc gtttggacaa ccacttgaaa tattttatct caaccatgga atccggtcac
    16441 ggccaaggca agaagctcgg ttttatcgct caggaaatgg ggcgtgagat caatacgctc
    16501 ggatcaaaga gcaaccacgc cgagatgcag aagatcgtgg tccagatgaa agacgagttg
    16561 gaacaaatca aggaacaggt actaaacgta ttataataag attaacgaga atggctggca
    16621 aattaattat cttctccgca ccctcgggtt ccggaaaatc aaccattatt aattatcttt
    16681 tgaaacaaga tttacacctt cgtttctcca tctcggctac cagccgggct ccgcggggaa
    16741 ccgagaagaa tggtgtggaa tattatttcc ttacgccgga agagttccgc agtcgtatcg
    16801 ctaatggaga cttcttggaa tatgaggagg tgtataccga taaatattac ggtacgttaa
    16861 agagcgaggt agagcgtatc ttgaacgaag gggataacgt gattttcgat gtggatgtgg
    16921 taggcggatg caatatcaag aaattctatg gagaccgtgc cctgtctgtc tttatccaac
    16981 ctccttgcat cgatgaccta cggaagcgat tggaaggacg gggaacagac agcccggaag
    17041 ttatcgaaag ccgtatcgcc aaggctgagt atgaattagg gttcacggga cagtttgata
    17101 aggttgtcgt aaacgatgat ctggagactg cccaaaaaga cgcgttgaag atcattcgtg
    17161 agttcttaaa caaatagtct atgtctaata tattcaagaa tacccgtttt atgatggggc
    17221 tttctatcgt ttgtgggata gcgagcctcg tattaggtgg tattagcctg tattataagg
    17281 agtatatcat cgggggtgcc ctgatattta atatattcat ttgtttcatc aactataagg
    17341 gttggcaaaa gaagggttaa gtaaaaatcg tatgggactc aagaccggga tttacagtgg
    17401 atcattcaat cccattcaca taggccatct cgccttggcg aactggctat gtgagttcga
    17461 gggattggat gaggtgtggt tcgtagtcac gcctcacaat ccgctgaaga aaaaggatga
    17521 cctgctcgat gactcactac ggctggaaat ggcccaagcc gctattgacg gatattctaa
    17581 attcagggtc tgcgatattg agttctacct accgaaacct tcttattcca ttgataccct
    17641 acgaacctta tcccgtaact atccgaatcg ggacttttat tttatcatgg gagccgataa
    17701 ctggcagctt tttccccgat ggaaagaaca cgaaaaaata ctccaagact acaaactgct
    17761 gatttatccc cgcctaggat tcgacatctc gatcccggcc atttatccga acgtgaaaaa
    17821 ggtagacgct cccttgatgg aaatctcctc cacatttatc cgtaacgctt accaagccga
    17881 caaggatatc cgtttcttcc tgccggaagg agtgcggcct tactactata agatctaaac
    17941 aaacctgtct gtcaacttat ataaccgaaa aaaagcagta gtacttactt gcccatagaa
    18001 tatatactgc tagtggcaaa ggatatatac ttacttagga aagttagtac tactcaatct
    18061 taaatgtatg agcgtactga ctatgcctaa atttacttca cagattttac tgttattttc
    18121 taaggtactt cacatcttag agaaccttct cctgaaaaac ttcacagggt tgaaagttag
    18181 tatgagctgt ttttctaagc ttcatgttaa ccgataaaag aacaaggaag ttcaaaataa
    18241 aattaggtta catcatttct catgaccttc ccgtaaaagt taatttttgt accctataca
    18301 attaaataga taaaatacat taaacaaaac acacaaagca ccgtttttct tgtttttaat
    18361 atttttttta attttatttg taaacatcaa agcattacac atctattaac tttttaaatc
    18421 tttcaaatta tggacaaact caaaaaactg acaaaagtcg tactaaacca acaaggtaaa
    18481 gttcttccaa aagagcaaat gatgaaaatc ttagggggag gaagtgcgta ttgtcattgc
    18541 tggaacagtt ccggttcctt tgaagcctcc agctgctctg agtgtgattc taaatgcaat
    18601 ggtcttggag gagtacaaaa ctgcaatacc ataggaggtt agtaacaaaa gaaagaacag
    18661 gttttagcag gcgccatctg ctaaaacccg ctttttttct taaaacaaaa acgatcatga
    18721 tctatcttct atttttagtc gctcttttgc ttatctgttg taatccggat caagccaagg
    18781 ataatagcaa ggacgaaaca atcgagtatt ttattccact ctcacatcgg gtagaaaaag
    18841 acgtggatga aatgtttgag gaatatcggt atgtcccctt ggaaacaaga gacgatgcat
    18901 tgatagacgt actttacaaa atcagaaaca tcgccctctt ccaagaggac atatacatcg
    18961 gctctgatga cattttaata gcatatgata aatcaggaaa aatcaaacgt gtcttatcta
    19021 aaaaagggga ggatccacaa tcatacttct tcttagggaa tttcacgata tggcctaatg
    19081 gggatatctt aatttcctca tcaggagatg tcactactta ttccaattcg ttcaaattta
    19141 ttcgcaaatg gagtgatcat gagaatattg gacttataga ggctatcatc ctattcaatg
    19201 acagctcata cattataaaa tgtacgccta ccgagaggca attgcgttac agaataatca
    19261 atcataagaa cggaacctat atcagcacct atgactccat agagaaacaa aataaatata
    19321 tcagctcatt cacaaactca ttcgaacgtt ttgaaggact tataatctct catggctatc
    19381 aaggcaatga gatacttgag tgtacgatgg atagtactaa agttcgatat cgaataaata
    19441 tcgacaataa aattcctcca gcgggatttt gggcacaaga cggaaaggac tatgtgcaaa
    19501 tcgtaatgga ggaagctgaa aaaggataca tcggtcatat cccagattac gtggaatcaa
    19561 aggaaacaat attactctcc ttcaagggaa aaagggatga tcttgaaggg gttgccttaa
    19621 tcgacaaaaa agatggaaac gcaagagttt tagagaacat caagttcgat gacaacttcc
    19681 ggtggttgcc caaacagttc ttctcgttag atgagggctg gtgcgccatg ctaatgtatc
    19741 cggaagacgt tttgaagaag gaagagttcg cacgacgctt ccccggactg aacgaggaga
    19801 gtaatccagt gctgtttatc gggaagctga gataatcact aaaaactcta agctatggaa
    19861 catgacaatc tgttcatcca aattttagaa atcttatcga taaaatacac gaaggatttt
    19921 accctaagat tctacgagaa gcatccacac aaaaacagcc tgtttggatt atccgagatg
    19981 ctacgttatt ataagataga gaatgtagca gccgaaattc aaaaaacaca agaatgctta
    20041 tcctcattgg atgtaccctt tgtggcttac gtagatcatg agtttgtatt ggtacgacat
    20101 gtttctaccg aggcaatcat ctattcatgg cgaggtaaaa acatcacatt atctatcccg
    20161 gtattcttgg aacgatggtc aggaatcgtc cttcttttcg aatccaccga tgaatctatt
    20221 gaaccggatt ataaagagca tagaaaggaa tacttacgac agcggatagt aatcgcatgt
    20281 ttcgtttcat tacttctatc attaataggg tgtgccctta tcaccaacag aggaatggag
    20341 ataggaatct gggggttatg gggtgttaat gtgatcggag catctttctg cggtatcctg
    20401 ctttctcgag agatcttagg ctcggataaa tatgtcaaca aaatttgttc cttgtttttg
    20461 aaatccagtg attgcaacgg gacattggat tcccaagcat ctcatttctt ggggatcagt
    20521 tggagtgtct tcggcttagg atattttctt tccgcaatat tgtttatcgc cttgttgccc
    20581 caatatgtta tatatgcaga gactctgaat ataatcgcat taccttatac agcgtggagc
    20641 gtatggtacc aaaaatttag ggtaaaacaa tggtgcgctt tatgtttatc tgtacaagct
    20701 accgtatgga tcacctttct tatctctcta tttgcgatag gcatggattt caatcaatgg
    20761 gatttatttg atttcactac cattggatgc gtgtatgggc tcgtcattct atcgctccat
    20821 tttactgtta cattatacgt aaaagaaaag caaatccaac gaagcaacaa taaacttagc
    20881 agcataaaac tgaatgcctc tgtatttaag agcttattaa acgaacagcc tcaatatgac
    20941 attgacaaaa atacaggaat attattgggc aatagggatg ccaaagagtg gattaccatt
    21001 atctctaatc cacactgtgc tccttgcgca aaattacatc tccaaataga aaagttactc
    21061 aaagaatata aagaagagat ttgcatacaa atcatcttga cctcttttag caaggaatta
    21121 gaacctagcg ccatgctact gacctccatg tatctactaa ataatgaatc ggattattta
    21181 cgattcctat ctgactggta tgcaaaaggg cgtcataaaa aagaggattg ctataaaaga
    21241 tacagattaa atcctaatga caaagatatg ttagccaatt ttcaagcaca aaacgaatgg
    21301 gttaggcgca atacaataag ttccactcca acagttttga caaatggtta tttattgccg
    21361 gaagaatatg agttaaagga tatgtcgtat ttaataaatt aagtactatg aataaattag
    21421 catcacaaat agattcgcta aataagcatt tgataggctc attacataca agttaccctt
    21481 tcgggttggc tcatggcaaa atgggattac tcatctattt ataccatttg tatgattata
    21541 cgcaagaagc tatttataaa gagaaggctg agcgattgct ggacgatctc ttggaaaacg
    21601 atctctctaa aaacgcagaa ctcaccgtgg aggaaggttt atgcggagtt gcgttaggat
    21661 tggattatat tgtaaaaaag caatttgtag acggtgatat taatgatttg ctaagtggta
    21721 tcgatgattt gctattcaag aagctggttt tcggaaatat ggaatctagg tattccctgt
    21781 ctcaactcat ccatttctta tattacattt ataaaaggct ggaaatccag acaaacgata
    21841 atgagcgttt ccctttcgag ggcttagcaa tcaagttagt taatcaattg gccgatttga
    21901 tagacgcctc ctttttcgag gaatcctata cgttttccat ttaccaatat cacgtaccga
    21961 tattaatgaa aaccctgtcc tgtcttatac aatatgattt ttacaaggat cggatacaaa
    22021 aggttctgga acaactatct ctgtatatgt tctcccattt gcctcatctg catttgaacc
    22081 gactatatct gttatggggc atgttacctt tacgggtttg ttcgccggat tggcaaagat
    22141 atgtggatga actaagaaaa tcaatcaacc tagacataat atataataga gagatcaaag
    22201 gcagggatat ctatatcagt aatggatacg cttctctata tttcttgttg gagggattaa
    22261 aaagggactt ccccgaatac accatccctt tcaatccgca cctaatttac gatcggatca
    22321 tctcgtctga cgcttgggat gccctaatgg agaacgaata ctactataat atacacagag
    22381 gattgctgaa tggtttcccc ggtacggtgt tggcattgtt aaacattaag caaagatatt
    22441 tatgcgaata gacttgacag atacaacatt tattattcct gtacggatcg attccatgat
    22501 ccgtttggag aacctgttga tgtccgtgga ctcaatagta cgttatttcc ggacacgcat
    22561 cttaattctg gaggcctcat cataccaaaa tgagattatc ccctcgttaa taaaagatga
    22621 tacggtgaag tacactttcc tcgtggataa agatcctgta ttctacaaga ccaaatactt
    22681 gaatatcctc gcaaagcagg ttgatactcc acttgtttgt atttgggacg cagatgtgat
    22741 actggaccac cttcaaatat tggatgcggt gaaacagctt agaactagga cttctgatgt
    22801 cgcttatcca tatgatggta attttttaga tacgtcagat atattgaggg aacattattg
    22861 gctccatcgt gacttagatt tcctaaaaaa acatcaagca aagatgaact ctttgtacac
    22921 agtagaggga gtgataggcg cagtcggggg agcggtcttc gcccaaacgg aaaaatacct
    22981 gcaagcgggt atggagaatg aggatttcta tggctggggc ttggaggacg gagaaagaca
    23041 ttaccgttgg ttgagttttg gctaccggat ttatcggagt gagggctgtt tattccattt
    23101 gtctcatccc cgggatcaaa atgggatgtt ccgttcaagg atacatagcg aaaaagcgat
    23161 gcatgatatg aatgaagtag taaactattc caaagaggaa cttcgagaaa agttctcctt
    23221 ggattcaaga tagagaattg tatttagtga tgaaagataa aattattggg tcttaagttc
    23281 attggcctac aaacctaaga tacttcacca aggatcctaa gagactttat ccatgaacaa
    23341 acaagatcgg tgacctcaac cttttaccac ataagtcagc ataaatcaga aatattttgt
    23401 acttttgcgc cgtattatac aaaataatag cataatgaat ctattagaac tgagtgaaca
    23461 ggaaataata agacgtaata gcatggagca gttgcgtcag atggggatag agccttatcc
    23521 cgcagctgag tatgtaacga acgcattttc caaagaaata aaagagacat tcaaagacga
    23581 cgctgagcca cgcccggtaa gtatcgccgg ccgtatcatg agccgtcgta tcatgggtaa
    23641 ggcttccttc atggaattac aggattccga gggtagaata caggtctata tctcccgtga
    23701 cgatatttgc ccggatgaga ataaggacac ctacaatgtc gttttcaaga aattactgga
    23761 tatcggtgat ttcgtcggga tcaagggatt cgttttccgt actcagatgg gagagatttc
    23821 cgttcatgcg caagaattga cagttttgtc taaatcactt cgtccgctac cggtcgttaa
    23881 atataaggac ggtgtcgctt acgacggttt taatgacccg gagcttcgtt atcgccagcg
    23941 ttacgtggat ttggtagtaa acgagggtgt aaaagatatt ttcatgaaac gtgcggctat
    24001 catcaagacc atgcgtaccg ccttggatga ggccggatac acggaggtag agactccgat
    24061 cctgcaatct atcgcaggag gagccagcgc acgtccattc atcacgcatc acaactcttt
    24121 ggatatcgat ctgtatttgc gtatcgctac cgagttgtat ttgaaacgat tgatcgtcgg
    24181 tggattcgag ggtgtatatg agatcggtaa gaatttccgt aacgagggta tggaccgtac
    24241 gcacaacccg gagttcactt gtatggaact ttatgtccaa tacaaggact ataactggat
    24301 gatgagcttc actgagaagc tgttggagcg tatctgtatc gccgtgaacg gtacgagcga
    24361 gagcacgatc gacggtaaga caatcagctt caaggctcct ttccgccgct tgccgatctt
    24421 ggaggcgatc aaggaaaaga cgggttacga cttggaaggt aagacagagg acgagattcg
    24481 tgcgatctgc aaggaattga agatggagat cgacgatacg atgggtaaag gtaaat
//
