LOCUS       gnlProkkaPEAONDNJ_1    14315 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PEAONDNJ_1.
ACCESSION   gnlProkkaPEAONDNJ_1
VERSION     gnlProkkaPEAONDNJ_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 12:44:50
            Original ID  :: gnl|Prokka|PEAONDNJ_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 5490260
            Orig. end    :: 5504575
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14315
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:9315]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9315
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..14315
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14315
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="2"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(167..1207)
                     /locus_tag="ctg1_4595"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQRELDN
                     ALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAATA
                     AVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKGVE
                     KSKIKLERSIATRKYIPAGSIIQESDIHLLSPGDGYKWIDKKNVIGHFAKQDISANEII
                     YPDFIE"
     CDS             complement(1182..1955)
                     /locus_tag="ctg1_4596"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKILNNEEYLYYW"
     CDS             complement(1964..2266)
                     /locus_tag="ctg1_4597"
                     /transl_table=11
                     /translation="MITDYTSTYFDFLLVNKPVIFNFYDIEEYRRVRGFSFEPIEFFCA
                     GDIVYNYNELIDAVMGLLAGKDIHAEHRRHISLLMNQFQDDNSTKRICDIFLNEI"
     CDS             complement(2263..3222)
                     /locus_tag="ctg1_4598"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFVFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKIYPKVYLFLNKHINMDCMIFCHFQME"
     CDS             complement(3519..4658)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_4599"
                     /sec_met_domain="Polysacc_synt (E-value: 2.7e-29, bitscore:
                     100.7, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENLKQKTVSGIMWSAIERFSLQGVQFIIQIILARLLLPSDYGMI
                     GMLAIFLQVAQVFIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIA
                     DFYNMPTLVLVIRFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWM
                     AYVGCGVWALVWQTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLIN
                     TVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFPSNNLNALVSRVAYPILSSIQDDDKCL
                     TNAYRNYIRLSSYIIFPLMVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQ
                     INLNLLWVKGRSDLSLRLEIIKRRLLYSFFLCQFHLGLR"
     CDS             complement(4861..5004)
                     /locus_tag="ctg1_4600"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             complement(5001..6122)
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg1_4601_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4601"
                     /sec_met_domain="Aminotran_5 (E-value: 6e-29, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        complement(5025..6032)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_4601_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg1_4601_Aminotran_5.1"
                     /locus_tag="ctg1_4601"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             complement(6310..7257)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 48.9;
                     E-value: 7.2e-15)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4602"
                     /sec_met_domain="TPP_enzyme_N (E-value: 2.8e-18, bitscore:
                     64.3, seeds: 75, tool: rule-based-clusters)"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.8e-15, bitscore:
                     54.7, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAVGIASGYYMASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRG
                     EPGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAII
                     IRKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKE
                     QGHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNY
                     YHILFNNGAHESVGGQPTLGFSLDIPAIVRGERI"
     CDS             complement(7274..8575)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4603"
                     /sec_met_domain="CTP_transf_like (E-value: 7.7e-11,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 8e-119, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 9e-61, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             complement(8596..9315)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_4604"
                     /sec_met_domain="NTP_transf_3 (E-value: 6.4e-14, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             complement(9379..10527)
                     /locus_tag="ctg1_4605"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELLEMEVSVSKKDDKMTLGSYLDEESSPWWDYLIGFPGIVIGGVK
                     SLFGEDTVPASGGRQGTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITA
                     VIADSVVHKLQEYIIGYRTSKVKEDCAYLERLFKERQQEYYAAQRKYADYVDAHDNVVL
                     QSVRAEQERLQNDMSLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGL
                     KIYILLFVFLSVSGTLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             complement(10538..12949)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 32.3;
                     E-value: 7e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_4606"
                     /sec_met_domain="Poly_export (E-value: 4.3e-16, bitscore:
                     56.9, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIQRLFSILLFCLMLGSGSLMAQSMSDSQVLEYVKDGIRQGKEQ
                     KQLASELARKGVTKEQAMRVKQLYEQQNNVNTSKSTGTDINESRLREETKKNTSDMLED
                     HPTTQDLARGDQVFGRNIFNTRNLTFEPSVNLATPANYRLGPGDEVIIDIWGASQNTIR
                     QQISPEGTINIQKIGPVNLSGMTVSAANDYLKNALNKIYNGLNNTTDPTSDIRLTLGNI
                     RTIQINVMGEVVQPGTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVY
                     EFIMKGNTQDDIRLQEGDVVIVPAYDVLVKISGKVKRPMRFEMKKEENLATLIKYAGGF
                     EADAYTRSLRVVRQNGEEYEVNTVKDIDYNIYKMRNGDVVTAEAILNRFTNKLEIRGAV
                     YRPGIYQLSGKLNTIRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGT
                     SPNLALMKNDILYIPSIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKEA
                     ASTVRIDISRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILEPYDQVYVRRSPG
                     YQAQQNVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKK
                     RMGDVIRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIP
                     KNTNTVTINGAVMVPNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKG
                     SGKKQIEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             complement(12967..13281)
                     /locus_tag="ctg1_4607"
                     /transl_table=11
                     /translation="MLLPGGGSAGCVYLDDLSALQRSIHEKINDLYSQRGETPEQDATL
                     CLAILQGYNVSMYANPEDEERKQAVLTRSLSLLDVLPPSLLKQQLSAVCHGMQELCEIN
                     "
     CDS             complement(13346..13924)
                     /locus_tag="ctg1_4608"
                     /transl_table=11
                     /translation="MILRKKKSLNAGPINGTGEGVAHSKRWYVALVRMHHEKKVSEHLD
                     KMGIENFVPVQQEFHQWSDRRKLVTSVLLPMMVFVHVDPKERMEVLSFSTVSRYMVMRG
                     ESSPAVIPDEQMARFRFMLDYSEESISMNSSPLARGEKVRVIKGPLTGLVGELVNVDGK
                     SKIAVRLNMLGCACVDMPVGYVEPIMAAV"
ORIGIN
        1 gtttgatcat aaaacattcc gccatcagtc caaacgccat caatatctgt aagtataagc
       61 tttatctctt tcattttttt agtattttac ccttatttat taatcactac ttagcttata
      121 gcaggcagta ctctataccg taatacaagt tgcagtagga atatatctat tcaataaaat
      181 caggatatat tatttcattc gctgatatat cttgtttagc aaaatgacca attacatttt
      241 ttttatctat ccatttataa ccatcaccag gactcagtaa atgaatgtcc gactcttgaa
      301 taatactacc tgctggaata tattttcgag tggcaataga acgttcaagt tttatcttag
      361 acttctccac ccctttttct atataaagat cttcagtacc aagccaacac tctgctatgc
      421 gaatatctcg aatcatacga ttaaccccat ctggacctaa agagccaagc tggtctgttc
      481 ctttcatatg ccgatcaatt gttacatgct tttctataat ttccgctccc atcgctacag
      541 cagctgtagc agcagaaata cctattgtat gatcagaaaa acctatctca aacttattgt
      601 aatgcttctt caaatatgtt attgtacgta gattcaaatt atttggatga gttggatact
      661 gagatacaca atgtagaata gctatattac tatgatatct cgttatcaca tctaatgcat
      721 tgtcaagttc tctttgacca gccattcctg tcgataatat aataggaata tgagtttctg
      781 ctaatgcttc aagcaatggt aagttagtca aatcacgact agcaactttt agcctatccg
      841 gtgtgaacag tttaagcaaa gacagacatc ctttggcaca taacgtctcg ataaaatcta
      901 atcctaatga cttagcatat ttataaatct caaaatgcgc ttgatcatca agctcaagaa
      961 aagcacgatg ttcaccataa gtacgcccaa aagaattagg attgtcatat atttgattca
     1021 tttgagaaac agccaattct tctgataaat ctcttttagt cattttaaca gcattcattg
     1081 gcatgaaatc cataccaaaa acatcctcat gtacaggtcg tgagattaat tcaataatca
     1141 acttagccaa gtcaacagaa ccattatgat tctgccctat ttcaccaata atataagtat
     1201 tcttcattat ttagaatttt ttttatttgt tgtttcatca gttgaatgta ttctgcatgt
     1261 cttcgaacat agtctacaat cacttctatc gatatttcca ctcttttttc ttgtaaatcc
     1321 ctatatattc tctgtgctac agaaaaatct tctaacgtat caatcgtgag tcgaatatta
     1381 tgatgttttg acacgactgg agatcctgaa atccattgaa tattaaaaag ttcaggatga
     1441 ctatatatat aattagtaac atgttcacga tacaataaat catcagtaaa tcctataact
     1501 cgcttcagcg catcaagcgt tacaaattct ccccaaaaac cgaaatgagt tttaattgat
     1561 ggagtaccat caatatcaaa acttatataa tcgttacaag atttcattgc tatttcgacc
     1621 aattgccttg ccgcatgtac atctaaaaat ggattatcag aacatattcg gaatataccc
     1681 tgtatatcaa aatattcagc aacatcaatg aatcgtttta aaacatcatt ctcctcacct
     1741 ctgaagcact ttacccctaa tgcaagtgcc ttcttttcaa taggttcatt gataacagaa
     1801 tttgttgtag caataattac tggaatattc gatatagcag aaagcttatg aaccattaag
     1861 tcaagaatcg attgattacc atagaaaggt ttcaatattt ttccaggcaa acgtgtagaa
     1921 cctaaacgtg cctgcaccac aaatgcataa ttcattttat ttattatatt tcatttaaaa
     1981 atatgtcaca tattctcttt gttgaattat catcttgaaa ttgattcatc aataaagaaa
     2041 tatgacgtcg atgttcagca tgaatatctt tcccagccag aagtcccatc acagcatcta
     2101 tcaattcatt ataattgtaa acaatatcac ctgcacaaaa aaattctatt ggctcaaatg
     2161 agaaacctct tactctacga tattcttcaa tatcgtagaa attaaatatg actggcttat
     2221 ttaccaataa aaaatcaaaa taggtagaag tataatcagt aatcattcca tctgaaaatg
     2281 acaaaagatc atacaatcca tatttatatg tttgttcaaa aacaagtata cctttgggta
     2341 aatctttttt aagactgttt tattctgcaa aggatgtaat ttaagaatta aagccgcatt
     2401 aaacttcaat agtattttcg ataacttcaa caaatcacaa tcaacatatc cgagtattga
     2461 acgcaaatta ccttcagtaa cagtctcata atcacgaaaa gttggagtat aaactatata
     2521 tttagttaca tcatatcccg caaatttcga aatttctctt ttaataacat tgcaattatt
     2581 tttcgatatc aacaaatcat ttctgggaaa tcctaagact ttgaatttat catatgagat
     2641 tccacaatct attgaaatta ttctagcact taaacaagaa gtagcaatag agtaatcaaa
     2701 tgagttacat gttgtattac gaaatttatc ataagaatga tctcccatat gataatcatc
     2761 tttgaatgga gtataatacc ccaaacaaat aatctgttga gagcgttttt taaatgaaaa
     2821 atcataataa aaagtagctg taaaacattt acttgctcta caaaaaacaa aaaaggcata
     2881 caacatatcc ttaaaagata ctttattaaa gaaaaaacgt ccaacacatg cacataaaaa
     2941 agtacaccta atattaggat ttatgccata aatatattct tgatattctg aaatacgaga
     3001 agaatcataa atttcaacat atattttata atattcagca ctatcttttt ttagcaaata
     3061 atttaacaga acgagaacat tatctgacga ataatttata atatcatatt tatctgttct
     3121 acaattagga tgaggaataa aatacaatga tctactatca actggcacac aatggttaat
     3181 tatctttact attacttgaa aaatcttttt taatattttc atctatgttt ttagttttaa
     3241 tgatcaatgt taaaatacaa aaaaaagaat ctagcttaaa aagaaaagaa agtaaaatat
     3301 agaaggacat cccagtaata catccaatca caatttttac tatatcagtt tcaaagaaag
     3361 aaatacatat aaaaacgatc cccccattat gaaagagagt attaaacttg gaaatacatc
     3421 tttaacttgc aactttaagg tcaaatcaat aagagaatta gtataatatg tattcaaata
     3481 tgtcgctatc agagagtaaa taactctacc ccaacacatc acctcaagcc caaatggaat
     3541 tgacacaaaa agaatgaata tagcaatcgt ctttttatta tttcaagacg taacgacaga
     3601 tcagatcttc ctttaaccca taataaattc aaattaattt ggctcaaatg atcaaacatc
     3661 caatccaaac ataatatctg taaaagaata acaaccccag accatttatc tgttaacaat
     3721 agactaataa taggattagc caaaacaagt aaacctacca ttaaaggaaa aattatatat
     3781 gaggataatc tgatataatt tcgatatgcg tttgttaaac atttatcatc atcttgaatg
     3841 gaacttaaaa taggatacgc tactctagaa actaaagcat ttaaattatt ggaaggaaaa
     3901 atagcaaatt gttctgctct tgtatagtaa ccaagctcta caacagaaaa cttttttcct
     3961 attacaatgg tatacagatt acgatatact gtattgataa gacttgagat caataattta
     4021 gatccgaaat tgaataatct ttcaaaagaa cttttggaga aagtatgtaa aggtttccaa
     4081 tgaactaaac agtaaaacaa aattgtcaaa attatactat ttaagagagt ttgccaaact
     4141 aaagcccaaa ccccgcaacc gacataagcc atccatattc caatcacgcc tgatataaaa
     4201 gctgcaccta atgaaatttt agattgagtt ttaaagttta cagaaataat taatttcgtt
     4261 ctgtgaatag ccgataaagc atttattatc aacgacaatg ctataaaacg aattacaaga
     4321 actaaagtcg gcatattata aaagtctgca atcaaagaag ccgaaaaaaa caatatacca
     4381 tagaataata ctgcgacaag aatattaaaa taaaagacag tggcaaaatc ctcttcagtt
     4441 ctatcttttt tctggattaa agcatttgta aaaccgctat ctataaatac ttgagcgact
     4501 tgaagaaaaa tagctaacat cccgatcata ccataatccg atggtagtaa caaacgagct
     4561 aatattattt gaattataaa ctgtactcct tgtaaagaga aacgttctat agcgctccac
     4621 attattcctg atacagtttt ctgctttaga ttttccatta cttaaataca gtataaaaac
     4681 aactacattt accgatatca attatatttt tccaatattc tcactaattg gttattatct
     4741 tcttcgcccc ttaccgcaat tctaatatgg tctctcccac taaaagcaaa ttaccctaca
     4801 caaacattat ctcctataac taccgatgcc tttttataag aataaagaac tcctaatgca
     4861 tcacctcaaa ttaatattgc catatttgcc tactaagcga aagctacgaa taggcactcc
     4921 agaaataaca ctttccggat ggaagtgtat accacgaagg gaaaaataaa aatgacgaat
     4981 cttcaataat atttctgcaa tcatgacatc ggtaatgtga cgttataatg atttaatgca
     5041 gcttttagta ctttaaagaa gttctcaata tcatctactt ctatctctcc taaagcacag
     5101 attctaaaag tatcctcagt tgatatctta cctggataaa tcgtaaatcc acgctcataa
     5161 caataatcat gtattttctc aaaatcccag ttgggatctt ctgggtattg aactgagaca
     5221 accagtcctg actgccattc acgctttatt acacttttaa gaccaatttc atttatacct
     5281 gaatgaatag cctcaaaaac tcttttgtga cgggcaaact tagcttcttc acccacttca
     5341 aaatattcat ttaatgcctg acgagtggcg taaatagttt gtaccggtgg agtaaaatgc
     5401 atttcacctg ttctctcaaa attctcatac tgcaaataaa gattacaata gtaagaacgc
     5461 ttgggatatt tttttgaaaa cttaatctgt tcctcattgc ctataataaa agaaagacct
     5521 gtcatcgctt gaagtccttt ttgagcagat gccatacaaa aatccacatt atctttctct
     5581 atatcaaaag gaatcatgcc caaagaagaa gtagtatcga cgacaaattt agcctgatat
     5641 ttatgagcta tagcgcccat ctcgcgaata gggttcagaa ttcctgtacc cgtctcgtga
     5701 tgagtagtat aaaccatagc tatatcagga ttttcttgca acacattttc caccaccgat
     5761 aaatcaggac gttcgtaaac ggaaaattcc aaattaatat gaggcaaacc ataatattga
     5821 cacacttcta cagcacgggt actatatgcc ccattattca ctataagcac ccttttgtct
     5881 tcaggaagaa gagaatttag acatatatca atattgatgg ttcctgagcc acaaaataat
     5941 acagcggtat gtttttccaa attcccatga gcaactctga ccaaatcgtc ccgaagttgt
     6001 ttcatcatac ctgcgaattc tttctcgcga ggacaaatat ccggaacaac ttgtgccatt
     6061 tttacactgt cagtagtagt ggcaggccca ggatttaata atatttttct ttctattttc
     6121 atcgaatata tttattttaa aaaatccata aaatgctcct tattctctat aggagtagtc
     6181 gtgggacgtc ccaaattctc ccgagaatct attttaacct ttatttccaa caaaacagga
     6241 ccacataact ttggaagctg cttcattgct tcttcaattt caacttttgt acaaacagta
     6301 taagtatgct tatatccgct ccccccggac aatagccgga atatctaaac taaatcctaa
     6361 agtaggctgt cctcctacag actcgtgagc accattgtta aacaaaatat gataatagtt
     6421 tttaggagat aaatcgccaa tgttactaat tgcccctaaa tgcataataa atgctccatc
     6481 accatccaag caataaacag gtctatcttg ctttgctata gcaataccca aagagattga
     6541 tgaactatgt cccatagagc ctaccgtgag aaaatcatgt tcatgacctt gctctttcat
     6601 ttctcgatat tcaaataact cacgagaaag cttgccagta gtagaaacga ccactgaatt
     6661 ttcaggcaga taatccacaa ctatttgcaa agcatcctca cgagataaag gataattaca
     6721 tccgaactct ttttgaagtt tatatttgcc aaaaacatct ttccgaataa ttattgcatg
     6781 aggaatattc ttagtttttg ctgattgtat gatatcatgg agctgaataa atgcatcatt
     6841 ctcatttgaa tcaagaatta tataaggaat ccgcattgct ttcaacaaat ctaaagttac
     6901 ctcaccctgt tttttatgct gaggttcatc ttttgttccc ggttcaccac gccagccaat
     6961 catcaaaagc attggaaaac tgtatacttg ttcatctgca agagacagca gaggattaac
     7021 agtattaccc aagccggaat tttgcatata aaccacagga accttacctg atgccatata
     7081 ataacctgaa gcaattccta cagccgcacc ttcattagca gctatgatat gtttctcacg
     7141 tgaagtatgg tctgtgatat aggcacaaat attttttagt aatgagtctg gaactcctgt
     7201 aaaaaaatca acgtcatgac tcagaaacgt ttcataaact ttttctacgc ttaacataat
     7261 gatattcctc tttttattta gtacctggaa tcagttccaa tatttctttt atgggcatac
     7321 acagttcgcg cacctctaaa gcacgttcat tctctaatat tatctttgcg acattcatca
     7381 tagcaggata agcggcacga agcatatgat tagcataaat aattatattc acaccccaat
     7441 cacacaattc agactcataa atatgatcat atgtagtagg cacaaccacg ataggtacat
     7501 gagcatactg ttttcgaaac gccaaacaaa attcttttat atcttcaccc gacttatttt
     7561 tgctatgtat cataataccg tccgctcccg cttggacata tgcaaaagct ctctctaaag
     7621 catcacttac cggctttccc gctataaggc tctcaatacg agcgataatc ataaaatcat
     7681 cagtaatctg agatgccttt cctgctttga tcttattaca gaaaccttcg attgtatctt
     7741 gagtttgaat aacatctgta ccaaacaatg aattcttttt taatccaact ttatcttcaa
     7801 ttattatagc tgaaattcca tgacgttcta aagtgcgtac tgtaaatacg aaatgttcaa
     7861 ttttaccacc tgtatctcca tcaaaaataa taggtttagt agtacactcc agaatattat
     7921 tcaaatcttg caatcgggta gttaaatcaa ccgcctcaat atcaggttta cctttactgg
     7981 ttgaatccgt aaggctacta gaccacattc cgtcaaatac ttccctctta tcccctttta
     8041 atatttcctg attttcaatt atcaagccac atagtccatc atgagcttcc aaaatacgaa
     8101 ctacgggttt ggcatttatc aaacgacgaa gtgattttaa acgtacatca ggggttgtac
     8161 ctatagcctt aatatcttta tccaaagaag atgaattaat tcccaaagta tatggaattt
     8221 cgataacctt tcctccctgt tcattcatca cttcaaatac gcgcacacgt tcttcacgta
     8281 aaggcccggt tttccagtcg tcaccatgaa ttatatagtc aggtttaatg cgtttgagat
     8341 tctcaacata gctccattct tcttgaggaa caactttaca tacgccttta atattctgaa
     8401 ctacctcttt tcgttgttca taggtcagat aaggaaggcg tttatgctcc gcaatagctt
     8461 tatctgtaag aagaccaatt ataacatcac cgtatttagt agcctcatta ataatgcgga
     8521 taagtcctgg atgcataata tccgcagtca tcccaatata aactgtctta ctcataattt
     8581 gatatattat tttaattaac aatacggaac aatatatttc tctgcatatt ccaaatctga
     8641 tatgtcatcg atttcatacc atttcagccc ttctacttta tgcacataaa caggagattg
     8701 agaacaagat attcgtagta attcatactc atatcccaaa ttgggttgtt catcaacaat
     8761 actcgcataa tcagcacaca ttattttgta aaaggaaccg gatagtttat ggatgccgac
     8821 caattcgcct ttagcgttta gtttattctt attgacagaa catgaagaaa ggcgaaaatt
     8881 atcatcatgt tccacataat actgatcttg aaactttgtc actggagtta ttagcattgc
     8941 atctgccgca ggacactcca ataagctcat tattgcttgt ttctcaaaaa tcaaatctga
     9001 ctctaacaat aaaaaatcat cattgcccag aatctcccgc gtattatata aagtatacat
     9061 actatttgtt tcagcataac gaggactaaa acaggtttca agcataggat agtctgtctt
     9121 caattcttca taaacttctt gtttatatcc tgtaccgatt acaattcgct caatgtcaca
     9181 tgataacaaa gtatcaatag aacgaactat cattggaata cctcccactt tgacgaaccc
     9241 tttaggtatc aattctgtat attggccaaa acgggttccc atgcccgcag ccattatcat
     9301 agctgtacgt atcattcgtt taataatata gtaagtgaat ttaattgatg taagaatgtt
     9361 gtaaacgacg ttttagcatc atttatcctg ttctatctcc ttatttttca gttcttttct
     9421 caagctagcc agcagacttt tgccaaaaaa cacccacacg agagtaccag atacggacag
     9481 gaacacaaat aataaaatat aaattttgag tcccatacct gaaggtttca aaggtacaac
     9541 ggcaggctca actactgcaa agactggctt ttcctcctgt actttggctc tggatacctg
     9601 caactgatta gcaacctgac tatatatctg ataagccaaa ctcatgtcgt tctgtaaacg
     9661 ctcctgctca gcacgtacac tttgaagaac cacattatca tgggcgtcta cataatccgc
     9721 atattttctt tgagcagcat aatattcctg ctgacgttct ttaaacaacc gttccaaata
     9781 cgcacagtct tcttttactt ttgaagttcg atacccaata atatattcct gtaatttatg
     9841 aacgacagaa tctgctataa ccgcagtgat ctgcggattt tgtaaggtga ccgtaatgct
     9901 cgttatggcg gttttcttat caatggatgc actaatcttc tttttaagaa aattaatctt
     9961 ctcatttact tctttcgtca attcgatagt tccttgccgc cctccactgg caggaaccgt
    10021 atcttctccg aataatgatt taactcctcc tattactatg cccggaaaac ctataagata
    10081 atcccaccaa ggagatgact cttcatcgag ataagacccc aaagtcattt tatcatcctt
    10141 tttagaaacg gagacttcca tttctaaaag ttccaataaa aaaggagttg aagaaacaat
    10201 atctgctgaa agagaagcgt tcaaggcatc tgtgctttcc cctattagag ccccatctcc
    10261 caaaaacgag gcagcaagtc cggctaaacc attacttccc ttcgcattac ccatttcagg
    10321 agaaagggta acctttactg tatattgctt gggaatgctc aatgccacca ctatagcaat
    10381 tattactccc actccagcag ctttgcatag tactccacga acagtaataa tcttataaaa
    10441 aatagccatc aagtctattt ccatttcatc atctttcctt ttatccactt cagaaaacgg
    10501 ttcttgataa gattgctttt caatcataat aggtcattta tttctttatc aaattagcaa
    10561 tagaagcaat catcattccc aaagaactga aggaagtagc ataacctaaa atattagcta
    10621 tgttcccttt cttcttagcc ttaccaggca caataatctc acaccccggc tcaatctgtt
    10681 tcttaccact acccttaacc ttcgtcacct gaccattcat gtaaacaatg aacttcttac
    10741 tcttccttgc attatcagaa cagccaccgg cctgattcag gtaataatcc acattctttc
    10801 ccttcatata agaaaccgta ttcggaacca tgacagcacc attgatagtt acagtattag
    10861 tattcttagg tatggagatc acatcacctt cacgtaagac aagatcggca ttacttttag
    10921 gattgctcaa ggctttttcc aaatctattc caaccgtaaa ggtatcttca acacgaatac
    10981 ccaaagagtc aatcatggct tcgcccaatt gcctgctcat aaggcgaatt acatcaccca
    11041 tacgtttctt ttcactagcg ttagccacac gggtcagttt cgcaccacgc agataggcat
    11101 aattggtcgg accaccggct ttattcacta aatcggaaag acgttcctca cggctggtca
    11161 tggcgtaatt tcctccgaaa aggatttcac cttcaatggc tacattctgt tgtgcctgat
    11221 agcccggact gcgacggaca taaacctgat cataaggctc aaggataaaa ccgggctgac
    11281 catctattac aaaaccatcc tttaaagaga aggtatacat ctgaccaatc gtatcattat
    11341 ccgcagtact acgaggattc ttgattcgtc tcgatatatc aatacggaca gtagaggcgg
    11401 cttctttcaa gccaccggcc tgaatgatca gatcctcaag tgtcatgtta tccgcataag
    11461 gataggaatc agggtgggca acctcaccgt gaactgtgac attaccccgg tcttccaggt
    11521 catggatact tggaatgtag aggatgtcat tcttcattag ggcaaggttt ggggaagtgc
    11581 cgtccatgat agacttaatg tctatctgaa caacttcact ggtcaggtct tcacgctggc
    11641 gatagaggac ggcacgattc aggaaagcgt caccggtcag accctgagct tcatggacaa
    11701 gttcgcggat cgtgttcagt ttaccgctga gctggtagat accgggacga tagacagcgc
    11761 cacggatttc cagtttgttt gtgaagcggt taaggatggc ttcggcggtt actacgtcac
    11821 cgttacgcat tttataaatg ttgtaatcta tatctttgac tgtgttgact tcgtattcct
    11881 caccattctg acggacaaca cgtaatgaac gggtgtaggc atcggcttca aagccgccgg
    11941 catatttgat taaagtggca aggttctctt ctttcttcat ttcaaaacgc ataggacgtt
    12001 ttaccttgcc gctgatcttt accaatacat cataagcggg aacaatcacg acgtcacctt
    12061 cctgaaggcg gatgtcatcc tgtgtgttgc ctttcatgat aaattcgtag acgtcgatgg
    12121 tggcaatatt ctttccgttg cgtaccaact gaacgtttcg gaggctaccg atatcactca
    12181 caccgcctgc acgataaagc gcatggaaga cggtagagaa ggaagaaagg gcgtaggtac
    12241 cgggctgtac gacttctccc atcacattaa tctgaatagt acggatatta cctaacgtca
    12301 gacggatgtc ggaagttgga tcggtcgtgt tgttcagacc gttatatatt ttattcaggg
    12361 cgttcttcag atagtcattg gcggcagaga ctgtcatacc gctaaggttg acagggccga
    12421 tcttctgaat gttgatagta ccttcaggag agatttgctg gcggatcgtg ttctggctcg
    12481 caccccagat atcaatgatg acttcatcac cgggaccaag acggtaattg gcaggagtgg
    12541 caaggttgac actaggctcg aacgtcaggt tgcgggtatt gaagatgtta cgtccgaaga
    12601 cctgatcacc acgggcaagg tcctgagtag tcggatgatc ctccagcata tcggaagtat
    12661 tcttcttagt ctcttcacgc aggcgggatt cgttgatgtc cgtgcccgtt gatttcgagg
    12721 tatttacatt gttctgctgc tcgtatagct gcttcacacg cattgcctgt tctttggtta
    12781 cacccttacg ggctagttcg gaagcaagct gcttctgttc cttgccttgg cggatgccgt
    12841 cttttacata ttccagtacc tgtgagtcac tcatggactg agccataagc gagccacttc
    12901 ccagcatcaa acagaagagt agaatgctaa aaagtcgttg tattttcatt gacaaataaa
    12961 aaagtttcag ttgatttcac acagttcctg catcccatga cagacggcag ataactgttg
    13021 cttaagaaga gaagggggaa gaacatcgag aagagacaga gaacgggtca aaacagcctg
    13081 ttttctttct tcgtcttccg gattggcgta catcgacaca ttatatccct gaaggatggc
    13141 caaacacagg gtagcatcct gctccggtgt ctccccccgt tgagaatata aatcgttaat
    13201 cttttcgtgg atggatcgtt gtaatgctga aagatcatcc aaatacacgc agcctgcact
    13261 ccccccacca ggaagcagca tacgtaccaa acttaataaa ccctctatat tttcttgtaa
    13321 aataatagca tccatatccc ttgccttaaa cagccgccat aatcggctct acataaccga
    13381 caggcatatc aacacaggcg catcccagca tattcaagcg aacagcaatc ttacttttac
    13441 catccacatt gaccagttcg ccaacaagac ccgtcaacgg acctttgatc acgcgaacct
    13501 tttcgccacg agccaaagga gaactgttca tgcttatcga ttcttccgaa taatcaagca
    13561 tgaaacggaa acgagccatc tgctcgtcag gaattacagc aggactactc tcgccgcgca
    13621 tcaccatgta acggctgaca gtagaaaaac tcaggacttc catgcgttcc ttagggtcaa
    13681 cgtgtacgaa gaccatcata ggaagcaaga cggaggtgac cagcttgcga cggtcgctcc
    13741 attggtggaa ttcctgttga acgggaacga aattctcgat acccatcttg tccagatgct
    13801 cggaaacctt cttttcatgg tgcatccgaa ccaaagcaac ataccagcgt tttgagtgtg
    13861 ctacgccttc ccctgtccca ttaataggcc cagcatttag tgatttcttt tttcttaaaa
    13921 tcatattttt ttaccccatg tttatccgtt acttcttagg taacgaacaa gcatagggca
    13981 agcagaaaag ggaacttttt tcaacgaaaa catcagaaga ggactggtat tcaggaaata
    14041 aagcagaagt gaaggtgttt ttcatgaatt ggaataaaaa aaagacataa cacggatatt
    14101 gtcattttcc gcctgttatg cctgcatttg attcattttc cgaaattaat ttcatttttg
    14161 tttgcgtatt ttcataaata tgtccatctt tgcgccatga atcattccgt tacctaagaa
    14221 gtaacgcaca ccgataaaca ctgtatatca agcttctaaa tcagatacac tgacctactc
    14281 cgcaccgctt tacgtaagac aaattcatcc ggttc
//
