LOCUS       c00004_gnlPro..        24857 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|IEDLPEAG_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 12:42:12
            Original ID  :: gnl|Prokka|IEDLPEAG_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 2766242
            Orig. end    :: 2791099
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24857
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[2776242:2781099]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14857
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..24857
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24857
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_fatty_acids"
                     /region_number="4"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(25..966)
                     /locus_tag="ctg4_2339"
                     /transl_table=11
                     /translation="MKTKITGLLTFLIGTFFFYSCDTDVEALEIQKLKTYDEQYFENLR
                     AFKKSDHEISYAYYEAWSPIEGVTGYKDPASWGERMVGLPDSIDIVNLWMGIPTAETHP
                     IAYADMQYCQRKLGTRFVMHADASHYRHQFTVDGVDYDLSQNKDDEAMAAYAKWIVNQV
                     LEPGLDGVDVDWEGWSGSDLVRLIKELGKYFGPEGEQPDKLLIVDYFSGTPPTDIIPYC
                     DYIVQQAYSDQVGFLTQPSNFPPEKMIYCESFGVFYADGGQLMNYARWEPSKGRKGGCG
                     VFYLGRNYYSSSGIPYNEFREAIQIMNPAVNE"
     CDS             complement(1009..2604)
                     /locus_tag="ctg4_2340"
                     /transl_table=11
                     /translation="MILNKILSWNKLSILGISLMLLNNISCIDYEDNVNPNEVTEEMME
                     VDNLKTGAFFSQMLRRVVIINDGDKLDSDYQIAQNLSHDLYSGYIAATLGSTNHNGQYN
                     FQEQWVNATFDYAYTGIMAPWQSIHKIATEQELPEVDALATIVKVEGMHRIADTFGPIP
                     YVNYGSSSLYDALDLVYNKFFEELDNAIEVLSNYVNGNVDAKLMSDYDCVYGGDVEKWV
                     KFANTLRLRLAIRVSYANPTLAEAQAKKSMENMFGFIESKAERAELSHNSLEYHHPLHE
                     IAYNFNSGDCRPGATIVAYLNGLNDSRISSYFTAADDGEYHGVRIGITTSNMSNYQGNK
                     ISNLNINRASTPVVWMTAAESFFLRAEGALRGWDMGGTAKSFYEQGVRMSFEENNAAGV
                     DDYLADHTSTPGAFADNVGSDNYTFSSRVTPAWDDNAGFEAQLERIITQKWIANYPDGP
                     EGWSEYRRTGYPEVIPVVRNSSNGTIDTQLQVRRLPYTRDEKINNASGVASGISALGGQ
                     DTGGTKLWWDKKSR"
     CDS             complement(2629..5928)
                     /locus_tag="ctg4_2341"
                     /transl_table=11
                     /translation="MRISLALLFAVVLQLSAENGYAQRTHVAISMNNVSVEQVLNKIEE
                     ASDYVFLYNDKTIQKNRIVSVRNKSGKILDILDDIFKGTDITYTVVDKQIILSTNKMQL
                     VQQEGQIQIKGVVKDAGGDPLIGVNVKVKDSTVGTITDINGNFTLQTRKGDILEISYVG
                     YATKTVKVQNAQVLNIVLTEDTEVLNEVVVTALGIKKEAKSLSYNVQQVSNAEITRIAD
                     ANFVNNLNGKVAGVTINSSSAGVGGSSRVVMRGTKSLNGNNNALYVVDGIPMSDMSAAS
                     TQPTDSYEGAGQSGDPISGLNPEDIESISVLSGPSAAALYGSAAANGVVMITTKKGREG
                     RTSVSISNNTTFSAPLVLPEFQNTYGQTEVGSYYSWGSKLNTPSSYDPKDFFQTGVNVT
                     NAASLSTGTDKNQTYLSLGTTNAKGIIHNNDYERYNVTVRNVAKMLKDKLTLDLSFMLS
                     SVKEQNMTSQGLYYNPLVPLYLFPAGDDFSKVQAYQRYDSERNLLTQYWPYSTSLALQN
                     PYWITEHIKIPNHKNRYMATASAKYEFADWINVTARAKMDRNNERRERMYDAGTNTLFA
                     SKYGYYSKSNIENQQIYGELLLNINKYFVDNTLNVTANVGGNFENNDYQSDYFGGKLKS
                     VANLFTFGNVDTSEKNLANQYGYHLKKRAIFGSAQIGYKSMAYLDVTARNDWSSTFKGT
                     NTGSFFYPSIGLSGIITDIFRCSTDIMPYMKVRISYSEVGNSPDVFLAIPTYALVDGVP
                     VTQSRRPNPNLKPERTKSWEAGFNFVFFKNRLRLDGSIYQSRTYNQFFERTLSSTTGYK
                     SEVVNGGRVDNKGIELSLRFEDKWGNFGWSSYLTYSLNRNKVVELLRNYEDPYTHELTS
                     LDRIDMGGTSMYKMILTEGGSIGDIYVNTLRTDEHGAIYVHPSDQVVVTQPDEFVKAGN
                     SAPKYNLGWGNTFSYKGLSLGFLFTARVGGVVVSQTQATMDAYGSSKATAIARDNGGAI
                     VNGRPIGAEDYYTKIGGAGAQGGIGSMYTYSATNVRLAELSLGYDIPINKYVDWIKGLN
                     VSFIGKNLFFLYRKAPFDPELTASTGTYFQGIDMFMSPSLRNLGFSVKVNF"
     CDS             complement(6178..7092)
                     /locus_tag="ctg4_2342"
                     /transl_table=11
                     /translation="MNPESLLRKAQALGEDIKEMESIDVMGAYQQAQTQIKTNRRRSMY
                     NQLMRYAAFLTIPLLLSSLILGYLYWGATDTEEKYAEVMAATGSVIRYELPDHSVVWLN
                     SGSTLRYPTVFKKDNRNVELKGEAYFEVEADRKRPFYVNTPAGLSVYVYGTKFNVNAYE
                     DDNSIETVLEKGKVNVISPDGKTTVQLAPGERLLYNKVDQKLLKGKVDVYEKVAWKDGK
                     LIFRNAELGEIFKRLARHFNVDIQFNNISGKEYKYRATFRNETLPQILDYLAKSAALKW
                     RTEEAVQQADDTFTKKKIIVDLY"
     CDS             7326..7895
                     /locus_tag="ctg4_2343"
                     /transl_table=11
                     /translation="MKISFSRQTKERAFKQLYEDYYAPFCLYAKRFVDDKEVREDIVSD
                     VFTSLWDKLDTDSFDLQSETALGYIKMCVKNSCLNFLKHQEYEWSYAENIQKKAPLYET
                     ETDSVYTLDELYRMLYETLNKLPENYRTVFMKSFFEGKTHAEIAEEMNLSVKSINRYKQ
                     KTMELLRNELKDYLPLFLLFLSPEQL"
     CDS             complement(7869..8972)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 52.9; E-value:
                     7.5e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_2344"
                     /sec_met_domain="AMP-binding (E-value: 3.7e-15, bitscore:
                     52.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFDRQKQRLLLEGKEYTPGDIHSLVAEGEGNHPSAIWDLYLFLN
                     EWFNDDPVITVHTSGSTGAPKELLVRKDQMIQSARLTCEFLDLKQGETALLCMNLRYIG
                     AMMVVVRSLIAGLNLIVRRASGHPLADVDTPLRFAAMVPLQVYNTFQIPEEKEKLKQTE
                     ILIIGGGAVDKALEEKIRNLSNAVYSTYGMTETLSHIALRRLNGAAASDRYYPFSSVEL
                     FLSSENTLMINAPLVCDDTLQTNDIARIYPDGSFTILGRKDNVINSGGIKVQAEEIEKL
                     LQSFIPVPFVITSVPDQRLGQAVTLLIEGQMEISALETKLESVLAPYYRPKYIYQVNHI
                     PQTGNGKINRKECRVLAESLQLLGRQE"
     CDS             complement(8972..9997)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_2345"
                     /sec_met_domain="MR_MLE_C (E-value: 1.1e-27, bitscore:
                     94.5, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNWVG
                     IGECAPLPNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQIEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSSKEIELRVDANGAFSPTDAMEKLKRLSELDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGYNTWEEKQRLLSAIRPQYIIIKPSLHGGLAGGEEWIAEAEK
                     LNIGWWITSALESNIGLNAIAQWCATFQNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFC
                     K"
     CDS             complement(10001..10825)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_2346"
                     /sec_met_domain="ECH_1 (E-value: 5.3e-80, bitscore: 265.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             complement(10829..12496)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_2347"
                     /sec_met_domain="TPP_enzyme_C (E-value: 1.5e-06, bitscore:
                     25.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPIVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMIIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKTGQMTPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPLLDN
                     RVPEYPRVWENYCKTIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYQVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIVIGDLSFFYDMNALWNINVRPNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFSNKNKDARILKDYYHQLKQK"
     CDS             complement(12516..13628)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_2348"
                     /sec_met_domain="Chorismate_bind (E-value: 8.1e-56,
                     bitscore: 186.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     FDLKELNGQRGFVIAPFRIDKSCPIVLIQSDRTGQPLPMEIVAEEEQDLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDATFDKLVLSRSLTIGKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLSLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             complement(13625..14857)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_2349"
                     /sec_met_domain="HBT (E-value: 5.5e-15, bitscore: 53.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKSLELGNYGGYILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNN
                     FALFTYHDDTIITDTPENEHIQNEARLNNLKVIKEEEFSVAIDFAPCKCMLVSDDEEAL
                     VSLEGHWKRRLNGALDVFRSEPYFLEVVPCAIDKANTLGALLEELDVKREEVIAIGDGV
                     CDVTMIQLAGLGVAMGHSQDSVKVCADYVTASNEEDGVALAVEKAIIAEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALGETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             complement(14942..15304)
                     /locus_tag="ctg4_2350"
                     /transl_table=11
                     /translation="MVQVRIKRVYEDFSETDGYRVLVDKLWPRGIKKEWLKYDYWAKDI
                     TPSAALRRWFHEDIPGHWNDFVVMYQKELEASQAVADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMHLKE"
     CDS             complement(15416..17143)
                     /locus_tag="ctg4_2351"
                     /transl_table=11
                     /translation="MKSIRSVICFCLFLFVFNQLLFADKTIENDSLYTSEYISRIYMAE
                     PERALSLLDGAESKKTIPLRIIHELRSRVYRNMYMTKLAFLYAKKSYLLDSVSQKDPKH
                     LLTMTVDLAELAVLMSDHKESMRYALDGIKLAQKEKDKGAESKLLFCIGENKWQLSFKE
                     EAYDYFDKAIKLLQGTSSKLEMAMLSYFYGMKMDYLLNDSRSKEALEVGLKREKLLKDI
                     AKLPEKTKGFLDLQYTYLYAKMSYICYLEGKYDQAEKYYQQYLSTENSQTPDGKTYAIP
                     YLLVSKQYQKVVDQCQDFKKLMQEQDTVNLQYISILQKEVKAYKGLKDFEKVAALRESI
                     ISIINGINSKDKQNAALELNAIHKADEQEEYIAEQTLQLRIRNISLAFLGCVTCLILFV
                     LWRIWRHTIIVKYKNKMLAKFINEKLAGKVENKQLFIDGDAEDPIAVPLDLEPETGFSE
                     KDDLSPDEVVESREEEDENKKIFKELNRIVVQDQLYLSPELSREDLAQIVHLNNARFAR
                     MIKENTGTNFNGYINELRINYAIQLLKQHPNYTIRAIADEAGFNSTPILYSMFKKRLV"
     CDS             complement(17522..18289)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_2352"
                     /sec_met_domain="Acetyltransf_1 (E-value: 9.1e-06,
                     bitscore: 23.4, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAKYITLTKENIEKEHICCAFSDKKCKDSYELKKTWLKNEFENG
                     YVFRRLDERAKVFIEYGPAEKAWVPVNAPNYLMINCFWVSGKYKGCGHGKALLQSAVED
                     AKAQGRDGLVTVVGTSKFHFMGDAKWLLRQGFETIEKLPYGFSLLALKINPAAPDPSFN
                     GTVSSGECEEKEGVVVYYTHRCPFAEFHVRNSLVGVTENKGIPLKIVRLETMAQAQNAP
                     TPATIFSLFYKGKFVTTDLSACMEQRFDKALGL"
     CDS             complement(18625..19875)
                     /locus_tag="ctg4_2353"
                     /transl_table=11
                     /translation="MKKNIRYNIVLLLLMVEAVLIPAFAQMPEIKLGQSISFEEYLNRV
                     AKKNLSYLAEKLNVSIADAEVIARKIFPDPELEFEAGNETFSLGVSYSLEMGNKRGARI
                     KLARTQAELEKLVLQQGFQDLRAEAADLFLEAILQRELLEVQKSSYEYMYQLSQSDSLR
                     YVSGEITENDVRQSKLEAVTLLNTVYSQEAAYHSALVLLNKHMGMSADTLHIPLGNWEE
                     LSRDFALSDLVKAGLDNRIDLLVAQKSTEVTTREYKLTRAERRPDIGVSVSYERNWNGF
                     LPPSRSATAGVSVPLTFSNINKGAVKAAKFRIAQSEIMERDMELQIQAEITQAWFNYEA
                     EKKKIAQYKAGVLEDSQKVLDGMVYKYKRGETSILDVLVAQRTYNEVQQEYLETMKGYA
                     ASLVALESACGIWDICF"
     CDS             complement(19853..22960)
                     /locus_tag="ctg4_2354"
                     /transl_table=11
                     /translation="MKKELMLSIIQKRWVMLCLFVMMCIFGYYSWKQLSIEAYPDIADV
                     TSQVVTQVPGLAAEEVEQQITIPLERAINGLPGMHVMRSKSTFGLSMITIVFKDGTEDY
                     WSRQRVQERLNEVELPYGAVPGLDPLTSPVGEVYRYIIESDQHSLRELTDLQNWVIIPR
                     IKEVSGVADVTNFGGITTQFQVEVDPSKLEQYNLSLSQVVEAIENNNANVGGSVLNRGD
                     LGYVVRGIGLIGNLDDLGHIVVSTTSGVPVFLNDIGSLKYGNLERKGVLGYTDRTRNYS
                     ESLEGIVLLLKHENPSKVLEDIHVAVDELNNETLPEGVRIHTFLDRTNLVDTTLSTVSH
                     TLLMGMALVVLVLILFLGNWRGALLVSITIPVSLLIAFILMHLTDIPANLLSLGAIDFG
                     IIVDGAIVMLETILKKREDNPKQYLEEKSMAQRAKEVGRPILFSTIVIITAYLPLFAFE
                     RVERKLFTPMAFTMSYAMIGALLVALLLIPGLAYAIYRKPHKIYKNKWLDRLKDKYIRT
                     ITRFLEAPLKAIIPSGLILTAGIVLSVVVGKDFLPELDEGSIWLQVNLPPGISVEKSRE
                     LSDTLRARTMKYSEVTYIMVQAGRNDDGTDPFTPSHFEVSIGIKPYDEWPKGKTKKDLI
                     HELEEEYKLLPGFKVGFSQPMIDGVMDKIAGAHSELVVKVYGEDFRETRRIAEEITRAL
                     GTVRGAVDLDIDQEPPLPQLQISMNRDAIARYGLNVSDVADLIEVAVGGKAIAQLYQGD
                     RQYGITCKYKEEARNTPEKIAGLMLTSSTGAKIPLSQVADVRLSVGESTITREMNRRHL
                     TVKLNLRGRDLTSFLNEAQNTINEKVHYDKNKYTIKWGGAFENQKRAYTRLAVIIPLTL
                     TGMFILLYVTFGKFRQAGLVLAIVPLALFGGMLALNVRGMTLNVSSAVGFIAMFGLSIQ
                     NGIIMVSQVNGLRRGGMELRKSVIEGARQRFRPILMTSITTILGLFPASLATGIGSDVQ
                     RPLATVIVYGLMFSTLISMFLLPAFYYLVENNVLNKKKNDEKEYTI"
     CDS             complement(22967..24076)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_2355"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 1.6e-07,
                     bitscore: 28.6, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMMKRELHTFIIGSVLFFTACGDKQESEQKSGYRIQGDTVYIADP
                     LLLEKIKVSVSELKPYSKKVITSGVVRPIPPRYAYVAPPFAGRVTKSYVRIGQSVRQGT
                     PLFEISSPDFTSAQKEYFQALSSRELAKKDLKRKEDLIRNGVSSQRELEEAQNALLIAD
                     KEFENASAALRVYQVDNLAEMILGQPMIVRSPIPGEVIKDNIVTGQYLKDDTEPIAIVA
                     DLSKVWIAAQVKEKDIRFINEGSNLDIEISALPGTVIKGNVYHVEEEVDEETRSIQVLS
                     ICDNLNGHLKLGMYTTVHFLSVPVRQIQIPEKALLQGEKDSYVFVQIAPLVFVRTSVTV
                     ETTENGIAVISEGLRPGDKIISEGGYYLK"
ORIGIN
        1 tcatgattct tatttattca ttgtttactc atttacagca ggattcatta tctgaatagc
       61 ctcccggaat tcattataag gtatacccga tgaagaataa taatttcttc ctaagtagaa
      121 tactccacaa ccgcctttac ggcctttcga cggttcccaa cgtgcatagt tcataagttg
      181 tcccccatcg gcatagaata ctccgaacga ttcgcagtaa atcatcttct cgggtggaaa
      241 gttactgggt tgagtcaaga accccacttg atcactataa gcctgttgaa cgatataatc
      301 acaataaggt atgatgtctg ttggtggtgt tccactaaag tagtcaacga taagcaactt
      361 atccggctgt tcgccttcag gaccaaaata cttgccaagt tcctttatca atctgaccaa
      421 atcggaacca ctccaacctt cccagtcaac gtctactcca tcaagtcccg gttccaacac
      481 ttgattcaca atccattttg catatgcagc catcgcttca tcgtccttat tctggctaag
      541 atcataatca accccatcaa cggtaaactg gtgtctgtaa tgagaagcat cggcatgcat
      601 gacaaaacgt gtacccaatt tccgctggca gtattgcata tccgcatatg ctatcggatg
      661 tgtctctgct gtcggtattc ccatccaaag atttacaata tctatactgt caggtagtcc
      721 taccatacgt tcaccccacg acgcgggatc tttatagcct gtcacacctt caatcggtga
      781 ccacgcttcg taataagcat aacttatctc atgatcgctt ttcttgaaag cacgcagatt
      841 ctcaaaatac tgctcgtcat atgttttcag cttctgaatt tctaacgctt ccacatcggt
      901 atcacaacta tagaaaaaga atgttccgat aaggaaagtc agtaaacctg ttatttttgt
      961 tttcatcgta attagtgttt ttagaattaa acaatgtcca ttctcctgtt atcgggattt
     1021 tttgtcccac cagagtttag ttccacccgt atcctgacca cccaaagccg atataccact
     1081 ggcaacgccg ctagcattgt tgatcttctc gtcgcgtgta taaggcagac ggcggacttg
     1141 taactgggta tcaatcgtac cattactact gtttcttact acaggaataa cttccggata
     1201 gcctgtacga cgatattcac tccagccttc gggaccgtcg ggataattgg caatccactt
     1261 ctgtgtaatg atgcgttcca actgagcttc aaatccggca ttatcatccc atgcaggagt
     1321 aaccctgctg ctgaaagtat aattatcact acccacattg tctgcaaaag cacccggagt
     1381 cgaagtatga tcagccaaat aatcgtctac accggcggca ttattctcct caaacgacat
     1441 gcgtacacct tgctcataga atgatttggc cgttccaccc atatcccagc cacgtaatgc
     1501 accttcggca cgcaggaaga acgattcggc agccgtcatc catactaccg gagtagaagc
     1561 acggttaata ttcagattag agattttatt gccttgataa ttgctcatat tgcttgttgt
     1621 gataccaata cgtacgccat gatattcacc gtcatcggct gctgtaaaat aagagctgat
     1681 tcgcgaatca ttcagtccgt tcaaataggc tacgatggta gcacccggac gacagtcacc
     1741 cgaattgaag ttataggcaa tctcgtgcaa cggatgatga tattccaatg aattatgcga
     1801 aagttcggca cgttccgctt tactttcgat aaagccgaac atgttttcca tcgacttctt
     1861 tgcctgtgct tctgccagtg tgggattcgc atatgaaaca cgtatagcaa gacgcaaacg
     1921 cagtgtgttg gcgaacttca cccacttctc tacgtccccc ccatatacac agtcatagtc
     1981 actcatcagc ttagcatcca catttccgtt cacataattg ctcaatactt cgatagcatt
     2041 atccagttct tcaaaaaact tattataaac caaatccaat gcgtcatata agctggaaga
     2101 gccatagttt acatatggaa taggaccaaa tgtatcagca atacggtgca tgccttctac
     2161 ctttacgatg gtagccaatg cgtcaacttc cggcagttcc tgttcagtgg ctattttgtg
     2221 aatactttgc catggtgcca taattccggt ataggcataa tcaaaagtgg cattcaccca
     2281 ttgttcctga aagttatact gcccgttatg attggtagat cctaaggtag cggcaatata
     2341 gcccgaataa aggtcatgcg ataagttctg agcaatctga tagtcagagt cgagcttgtc
     2401 gccatcattt atgattacaa cccgacgcag catttgcgaa aagaaagcac ccgtcttcaa
     2461 gttgtctact tccatcattt cctcggtgac ttcattcgga tttacgttat cctcatagtc
     2521 gatacacgaa atgttattta atagcatcaa agatatcccg agaatggaaa gtttgttcca
     2581 tgatagtatt ttatttaata tcatatcttc tacaatttat aagtttgatt agaaattaac
     2641 tttcacagag aatcccaaat tacgcagact tggcgacata aacatgtcga taccttgaaa
     2701 gtaagtgcct gtacttgctg tcagttccgg atcgaacgga gcttttctat aaaggaaaaa
     2761 gagattctta ccgatgaaag atacgttcaa ccccttaatc cagtccacat acttgttgat
     2821 aggaatatca tagcctaacg ataactcagc caaacggaca ttagtcgcac tgtaggtgta
     2881 catagaacca ataccaccct gagcacctgc acctccaatt ttcgtatagt aatcttccgc
     2941 accgattgga cgaccgttaa caatggctcc gccattatca cgggcaatag ctgtagcctt
     3001 tgaagagccg tatgcgtcca tcgtcgcctg tgtctgtgat acaactacac caccgacacg
     3061 tgccgtgaac aggaatccca atgaaagccc tttgtaactg aatgtgtttc cccaaccgag
     3121 gttatactta ggagcactat taccagcctt tacaaattca tcaggctgag taactacaac
     3181 ctggtccgaa ggatggacat agatagctcc atgttcgtcc gtgcgaagcg tattcacata
     3241 aatatcgccg atagatccgc cttctgtcag tatcatttta tacatacttg tcccgcccat
     3301 atcaattcta tccaaagaag taagttcgtg cgtataagga tcttcatagt tgcgcagcaa
     3361 ttccaccact ttatttcggt tcaatgaata ggtcagatac gaactccagc caaaatttcc
     3421 ccatttgtcc tcaaaacgca aagacaattc gataccttta ttatctacac gaccgccatt
     3481 gactacttcc gatttatagc cggtagtaga agaaagggta cgttcaaaga actgattgta
     3541 ggtacgtgac tgatagatag atccatccaa tctcaaacgg ttcttgaaga agacaaagtt
     3601 aaatccggct tcccatgatt tggtacgttc cggcttcaga ttggggttag gacgtcggga
     3661 ctgagtaaca ggaacgccat caaccaacgc ataagtcgga atagccagaa atacatccgg
     3721 tgaattacct acttccgaat aagaaatacg tactttcatg tatggcataa tatccgtact
     3781 gcaacggaat atatctgtga taatccccga aagaccgata gacggataga agaaagaacc
     3841 ggtattcgtc cctttgaagg tagatgacca gtcgttacga gccgtcacat ccagataagc
     3901 catagacttg taaccgatct gagcactacc gaatatggcg cgttttttca aatgatagcc
     3961 atattggttg gccagattct tctctgaagt atccacgttg ccaaaagtaa agaggttggc
     4021 taccgacttc agtttgcctc cgaaataatc agactgataa tcattgtttt caaagttccc
     4081 acccacatta gctgttacat ttagggtatt atcgacaaag tacttattaa tattcagcaa
     4141 taattcaccg tatatctgtt gattctcgat attactcttg gagtaataac cgtatttaga
     4201 agcaaacaaa gtatttgttc cggcatcata catgcgctca cggcgttcgt tgttgcggtc
     4261 cattttggca cgggctgtta cattaatcca gtcagcaaat tcatattttg ccgatgcagt
     4321 tgccatataa cggttcttat gattaggtat tttaatatgc tcggtaatcc agtatggatt
     4381 ctgtaaagcc agacttgtgc tgtaaggcca gtactgagtc agtaaatttc gttccgaatc
     4441 ataccgctga tatgcctgta ctttggagaa atcatctccc gcaggaaata gataaagagg
     4501 tactaacggg ttataataaa gtccctgaga ggtcatattt tgttctttta cagagctaag
     4561 cataaaactc aggtcaagag tcagcttatc tttcagcatc ttggcaacat tacggacagt
     4621 gacattgtaa cgttcgtagt cattattatg gataatacct ttggcattgg tagtacctaa
     4681 agataagtaa gtctgattct tgtcagtacc tgtagaaaga ctggcagcat ttgttacatt
     4741 cacacctgtc tgaaagaagt ctttaggatc atagctgctc ggcgtattca atttactgcc
     4801 ccagctgtag taactaccca cttctgtctg cccataagta ttttgaaatt cgggcaagac
     4861 aagaggagcg gagaaagtcg tattattgga tatgctgact gaagtacgtc cttccctacc
     4921 ttttttagta gtaatcatca caacaccatt ggcagcggca ctaccgtaaa gagctgcagc
     4981 tgacggtcca ctcaaaacag agatactctc tatatcctcg ggattcagac cggaaatagg
     5041 atcaccggac tgaccggcac cttcgtatga gtccgtaggc tgtgtagaag cggcactcat
     5101 atcactcatc gggataccat caaccacata aagagcattg ttattaccat tcaatgattt
     5161 ggttccacgc atcactacac gtgaagagcc accgacacca gctgaagatg agttaattgt
     5221 aacacccgca actttaccgt tcagattatt gacgaagttg gcatctgcaa tgcgtgtaat
     5281 ctcggcattg cttacttgct gtacattgta tgacaaagat ttagcttcct tcttgatacc
     5341 caatgcagta acaacgactt cattcagtac ttctgtatct tctgtcagca caatattcag
     5401 aacttgggca ttctgtacct ttactgtttt cgtggcatat cccacataag aaatttccag
     5461 aatatctcct ttcctggtct gtagcgtaaa gtttccgttt atatcggtga tagtaccgac
     5521 cgtagaatct ttcactttca cattcacacc gatcaaggga tctccgccag catctttcac
     5581 aactcctttt atttggattt gtccttcctg ctgaacaagt tgcattttat tagtcgataa
     5641 aataatctgc ttgtcaacta cggtatacgt aatatcggtc cccttaaaaa tatcatctag
     5701 aatatccaga atcttacctg atttatttct cacagaaaca atacgattct tctgaatcgt
     5761 tttgtcattg taaaggaaaa cataatcgga agcttcttct attttattca gtacctgttc
     5821 tacagataca ttgttcatag aaatggcaac atgcgtccgt tgagcatagc cattctctgc
     5881 agatagttgt aaaacgactg caaaaagtag tgccagacta atcctcataa ctaaaggtag
     5941 ttttagattt aaagcatatt taggatataa tgcaataaat gaatgatttt ttttcataca
     6001 tttgcggtta actaaagttt attactataa tgaactgtgg tttgattccg gttagcgttt
     6061 gcaagactcc ttaccgcgaa tctgaaaaat tgggggaaga cagctgttgg tagcagcttt
     6121 cttccttttt ttacgatctt tgtgttatct cataggctat tctcattttt atggttacta
     6181 atataaatct actattatct ttttctttgt gaatgtatca tctgcctgtt gtaccgcctc
     6241 ctcagttctc cacttcaagg cagcagactt agccagataa tccaatatct gtggcagtgt
     6301 ttcattacgg aaggtcgcac gatatttata ttcttttccc gatatattat taaactgaat
     6361 atctacatta aaatgccgtg ccagccgttt gaatatttca cccaactcgg cattgcggaa
     6421 tatcaactta ccgtctttcc atgccacctt ttcataaaca tccacttttc ccttcaacaa
     6481 tttctgatct accttattat aaagcaatcg ttctcctgga gctaactgaa ctgttgtttt
     6541 tccgtccggt gaaataacgt ttactttacc cttttctaat accgtttcta tactattatc
     6601 atcttcgtaa gcattcacat taaatttggt tccgtacaca tagacactta acccggcagg
     6661 agtattgacg taaaaaggcc gtttcctgtc cgcttctact tcaaaatagg cttcaccttt
     6721 taattcaaca ttacgattat ctttcttaaa aacggtagga taacgtaaag tactaccgga
     6781 gtttaaccag acaaccgaat ggtcaggaag ttcgtaacga atgactgaac ctgtagccgc
     6841 catgacttct gcatacttct cttcagtatc cgttgctccc caatataaat atcccaaaat
     6901 caaagaagaa agtaataaag gtatagtcaa gaatgcagca taacgcatca actgattata
     6961 catactcctt cttctgtttg tctttatttg ggtctgtgct tgttgatagg cacccattac
     7021 atcaatagac tccatttcct taatatcctc tcctaatgcc tgcgcttttc ggagcaatga
     7081 ttccggattc atattttcca tattctcttt caaaatctta tcttttaatt gcaattacac
     7141 taatagtaca actgaggtaa tcgaaaaggg acaggtataa catacttttt tttattttat
     7201 tttttaagct atcttatttt ccacagcttc ataccaaaaa caaaaaaaga aagaaaattt
     7261 taggaaatgc tgattttctt attatatatt tgcagtaaaa tgaaaaacta cagaatctca
     7321 aaataatgaa aatatctttt tccagacaga ctaaagaaag agctttcaaa caactttacg
     7381 aggattatta tgcccctttc tgcctgtatg caaaaagatt tgtagatgat aaagaagtcc
     7441 gcgaggacat tgtttcggat gtattcacct ccctatggga caagttggat accgactctt
     7501 tcgatttgca atcagagaca gcattgggat atataaaaat gtgtgtaaaa aacagctgtt
     7561 tgaactttct gaaacatcag gagtatgaat ggagttatgc cgaaaatatc caaaagaaag
     7621 ctcctctata tgaaacagaa acagatagtg tatatacact tgatgagtta taccgaatgc
     7681 tatacgaaac attaaataag cttccggaaa actatcgcac cgtatttatg aagagtttct
     7741 ttgaaggcaa aacacatgcg gaaattgccg aagaaatgaa tctcagcgta aaatccatta
     7801 atcggtataa acaaaaaaca atggaactcc tgcggaacga gttgaaagat tacctcccgc
     7861 tatttttatt attcctgtct cccgagcaac tgtaagctct ctgctaaaac acggcactct
     7921 ttacgattaa tcttcccatt tcccgtttga ggaatatgat ttacctgata aatatattta
     7981 ggacgataat aaggtgctaa gactgattcc aatttagtct ctagcgcact tatttccatc
     8041 tgcccttcta tcaataaagt aacagcctgc cccaaacgtt gatccggaac ggaagtgatt
     8101 acaaacggga caggaataaa cgactgaagt aacttttcga tctcttctgc ctgcacttta
     8161 attcctccgc tattgattac attatccttt cttcccagaa tcgtaaaact accgtccgga
     8221 taaatgcggg caatatcatt tgtctgcaga gtatcatcgc agacaagcgg agcattaatc
     8281 atcaaagtat tttctgaaga caaaaacaac tctacggatg aaaaaggata ataacgatcg
     8341 gatgctgctg cgccattcag acggcgaaga gcgatgtgag aaagggtttc cgtcatcccg
     8401 taagttgaat aaacagcatt ggacagattt ctgatttttt cctctaaagc cttgtcaact
     8461 gctccgcctc ctataattaa aatctccgtt tgctttaatt tctctttctc ttcgggtatc
     8521 tgaaatgtat tatacacctg caaaggcacc atagccgcaa accttaaagg agtgtccaca
     8581 tctgccaatg gatgaccgga agcccgacgt actataagat tcaacccggc aatcaaagaa
     8641 cggacgacta ccatcatcgc cccgatatag cgaaggttca tacacaataa tgccgtttca
     8701 ccctgcttta aatccagaaa ctcacaagtc aggcgtgcac tctgtatcat ctgatctttg
     8761 cgaacaagca attctttagg tgcccccgta gaaccggaag tatgtacagt gatcacagga
     8821 tcatcattaa accattcgtt tagaaaaaga tacaagtccc atatagcaga agggtggttt
     8881 ccctcacctt ctgctacaag gctatgtata tcgcccggag tatattcctt tccctccagc
     8941 aacaaacgct gtttttgtcg gtcgaatatc atcatttaca aaaccacaaa caatcttttc
     9001 tgatttcaag aggcatctct acattatctg taaagagtaa cccggtgcct aacccttgcg
     9061 gcaatggatt ctgaaaagta gcacaccatt gagcgatagc attcagaccg atattagact
     9121 ccagagcaga agttatccac caaccgatat tcagtttctc cgcttctgca atccactcct
     9181 cgccaccggc taatccgcca tgaagagaag gtttgataat aatatattgc ggacggatag
     9241 ccgaaagtaa tctttgcttt tcttcccagg tattatagcc tatcagttcc tcatccaaag
     9301 ctatcggcaa aggagattcg gaagtaagac gtgccatttc ttcccattgt ccggcacgaa
     9361 tgggctgttc tatcgaatgt aagtccagtt cggacaagcg tttcaatttc tccatcgcat
     9421 ctgttggtga gaatgctccg ttggcatcta cacgcaattc tatttcttta gaagaatagt
     9481 gagagcggat atgttggagt aaagccagtt cttcttcaaa gttgatggca ccgatcttca
     9541 actttataca gcggaatccc gcctccatct tcttctctat ctgagcaagc attctattga
     9601 agtcacccat ccagataagc ccgtttatcg gaatacctgc ttccccacgt gagaagggtg
     9661 tatcccacaa agcccagctt ccttcaaaaa agtgacgaat ggctgtctcc aagccaaaaa
     9721 ggatggaagg gtacttgcat agagcttcca tgtccagctt acctccctga ttctctacct
     9781 gccggcagat tttagccagc acttcctcgt aatcgggaag atcatcacag ctaagatttg
     9841 gcagaggagc gcactccccg atccctaccc aattgggaaa ttcgggagca gtaaaatgaa
     9901 gataccagac ttttcgcgtt gtgtatgtgc ctcgtgaagt tccggccggc tgcttgaaat
     9961 gaagcacccg cggaataatg tctattttgc aatccattgt ttaagggaac ttcggatatt
    10021 tcttaaagtt aggtttacgt ttctccagaa atgcattctt tccttcctga gcctcatccg
    10081 tcagatagta aagcaaggtc gcatcccctg ccagctcctg aatacctgcc tggccgtcca
    10141 gttcggcatt caatccggct ttaatcatcc gcaaggccaa cggactgagc agcatcattt
    10201 cttccgccca ttgcacatac tcatcctcca gttgctccaa tggaactact ttattcacca
    10261 atcccatatc caacgcttcc tgcgcattgt atttccggca aaggaaccat atctcacgtg
    10321 ccttcttctg accgacgaca cgagccagat aagaggctcc gaaacctgca tcaaagctac
    10381 ctacgcgagg accggtctgt ccgaagatcg cattctccga agcaatcgat aaatcgcaaa
    10441 ctacatgaag cacgtgtccg ccaccaatgg caaatccatt tacggcagca attaccggtt
    10501 tcggaatgct gcggatttgt ttctgtacat ccagaacact cagacgggga acaccgtcct
    10561 tgccgatata gccgccacgc cctttcacat tctggtcacc gcccgaacag aaagccttgt
    10621 caccagctcc cgtaatcacg atcacatcaa tatccgcttc ttcccggcaa atgcgcaatg
    10681 cgtcactcat ttcagccgtt gtagtcggag taaatgcatt tcgatagcgt tcacggttaa
    10741 tggtgatgcg ggcaatccca ttatagtaat caaagaggat atcttcgtat tctctgatgg
    10801 ttgtccattc tctttgtgtt gacataatct atttttgttt tagttgatga taataatctt
    10861 tcagtatacg tgcatcttta tttttattgc tgaatacttc catcagaacc ggttgttcca
    10921 tggcttccgg ttgtgtgaag gttttcatcg cttcggcaag ctgttcttca ttctctaccc
    10981 gttgataaag gaatccgcgt tcttccgccc atcctttggc agatgtcttg tgaacggctg
    11041 taatatactt gtgcgatgta cccgacatat ccagtccggg taatgtatgg aaaatctccc
    11101 ctcctccgtt attcagcaaa agaatgcgta gattgggacg gacattgatg ttccacaaag
    11161 cattcatatc ataaaagaaa ctaaggtcac ctataactat aaaatttagt ttatccgaac
    11221 cggcggcata tcccactgcc gtggacaacg agccttcgat gccgcttgta ccccgattac
    11281 agcatacctc aatcgtagaa ggaacctggt ataactgagc atagcggata acagaactat
    11341 ttgccagatg caatgcacat gattccggca atgcttttat caaagcaccg atagccgaca
    11401 tttccgaata tccgaactcc ggttcgggaa tggtcttgca ataattctcc catacacggg
    11461 gatactccgg cacgcggtta tccagcaatg gagctatttt ctccagaaac tcaaacgggt
    11521 ccatttcgat gacggtagtc agagaaccgt aaaggtcaac cacttctcca tcagcagaca
    11581 catgccaatg ttctttaggc ggatgctgcc gaagatattt tttcaaccgc ttggaaacca
    11641 catgtccgcc ataagtaatc aataactcgg gagtcatctg gccggttttc tcttcgggca
    11701 tcgcataaag cgccgcatca aaattcttca ctggaatacc gggtactgtc tgattaccga
    11761 tatgctcggt cagccacacg aaatgtttat ataacaattt ggtatgccgt ttctcaaaca
    11821 agtaaatcaa gttcatctgt ccgacaataa tcatccgctt ctgatatctg ttcaagcgtt
    11881 cgatcaggtc attgtaatcc cggtcgtata cattcagccc ctgatagcgc gtaatgacac
    11941 gtacttcggg aagcgactcc accgtaaact ggaacaaagg ttcggatata ggaatattaa
    12001 tatgtaccgg accttttcca tgatggttgg tttccagcaa ggcttcattc accaagcggt
    12061 tacagtacca ttcatcctct tctgtctgaa tctccggaag gtttaccgac ttcttcacca
    12121 atgtctgaaa aacaccgggc tgcggcaatg tctgtcccgc catctgtcca atccaggcag
    12181 caggccgatc ggcagagata acaactaaag gtatattctg ataatacgct tctgccacag
    12241 caggatgaag attgagcaac gctgtaccgg aagtacagca aacggcagca ggatgcccgc
    12301 cattcagcgc aagaccaatc gcaaaataac cggcactccg ttcatccgtc atagcataac
    12361 aagtaaaacc cggatgagta gacagcgtat gcacaatagg tgcattacgg ctaccgggac
    12421 ataacactac tttcgtaatt ccatgcgcct caagcagcgc gaccaactgg agtatatttt
    12481 tcttgtccga atacatattg atagtgatta gcttgttagt gattcatcat tattggagca
    12541 gacacaagaa tacgcctcat ggtctgcaat ttcttttccg tttcctgcca ttcatcattc
    12601 aactctgaag aggctaacaa tccgccaccg gcatacagtg tcaattgctc gtcttcaatg
    12661 tgcatgcaac gcagattcac atacaaatct gtgcgtccct ccggatcgag ccaaccgata
    12721 aaaccggaat aatacttacg atcgtaccct tcattttcca aaatgaaccg gtaggcttct
    12781 tctttaggca gtccgcacac ggcaggagtc ggatgcagga ctttcagaag gtctcccaga
    12841 tttttattat ctttcaaaga gaaatggaaa tcagttttca gatgtgacaa ggcaccggca
    12901 taagccggat aaggtccgct ctctgtggag cgaatgccca gcgaaagaag ctgccgacgg
    12961 atataggacg ccacataatc ctgctcctga cggtttttgt catcccatac ttgcggaagt
    13021 ttaccattct gcaaaggttg agttcctgcc agggcaactg tgttccattc atttttttcg
    13081 cccgacaata taatttcggg ggtacttccc agccacacgc ccgtctgagg agtataacac
    13141 agatagatat aggaatgaat ataacgttga caagctgcac gaaaaacagc tgaaggggaa
    13201 aactccggat tctttccaat agtgagacta cgggaaagca ccagtttatc aaaggtagca
    13261 tcacgcaagg cttcaataaa tgtatgaaaa caggtcgcat acttcccagt acaaagggta
    13321 tgaaaagatt cctccggata actttgcaag tcctgctctt cctctgccac gatttccata
    13381 ggcaacggtt gtccagtcct gtcggactgt atcaacacaa tcggacatga cttatctata
    13441 cggaacggag caatcacaaa tcctctttgt ccattcagtt ctttcaaatc gaaaatcaag
    13501 cggacagctc cgacatcttc tgtcaacaga cgaggatact tctccccggg aacacgataa
    13561 acagcaaagg gctgtttccg ctgaataagt gcatcaatag ttgtcaagtt acttttttcg
    13621 tcaatcatct ttttttcatc acactgttga ccacccgtat agaggacacc agtttattgg
    13681 ttgaagtaaa aacgtccaca ttccatacat gggaggaacg tcctttgtgt acaatcgtcg
    13741 ctactgcacg tactgtatca ccttcgtgcg cagaagatat atgatttccg ctgacctgca
    13801 ttcctaccac aatttcatcc ggctgacaga gaatcatcga gccgagtccg gcaactgttt
    13861 ctcccaatgc aagcgtagct ccaccgtgca aaataccgaa cggctgacgg gtacggtgat
    13921 ctaccggcat cgtcgcctct acacggtctt cgtcggcata tgtatattgg atacccagat
    13981 tacccatcaa tgcgtgacgc gcctgtgcat tcaactggtc caaaggaatc tctgcagcgc
    14041 gaacttccgc tattatcgcc ttttcgacag ccagagccac tccgtcttcc tcattggaag
    14101 ctgtcacata atccgcacag acctttaccg aatcctgcga atgccccatc gccactccca
    14161 gtcctgccag ctgaatcatc gttacatcgc acacaccgtc tcctatagcg atgacttctt
    14221 cacgcttcac atccagttct tccaataaag ctcccaatgt gttggcttta tcaatcgcac
    14281 acggcactac ttccagaaaa taaggttcgg aacggaaaac atccaaagct ccgttcaacc
    14341 gtctcttcca gtgtccttcc agactaacca acgcttcctc gtcatcgctg acaagcatac
    14401 acttacacgg agcaaagtca attgctacag aaaattcctc ttccttgatc actttcaaat
    14461 tattcaagcg agcttcattc tggatatgtt cattctccgg agtgtcagta atgatcgtat
    14521 catcatggta agtgaacagt gcgaaattat tttttcttgc cttcttttcc agataaggca
    14581 acatttccgg attaatcctc cgctcaaaca gtatttctcc gttttgagca ttaattatct
    14641 ggcaaccatt ataagaaagg atataacctc cataatttcc gagttctagg gatttggcta
    14701 aaggcatcag accgtaagtc ggtcggccgg atgccaacac gatacgtact cccatctgct
    14761 gaactttcag caaagcagcc aatgtacgtt tactaatttc ttttgcatca ttgagaagcg
    14821 ttccgtctac atcaagaact aataatttat acttcatgga cacacgattt tgatttagat
    14881 tacaaaggta ggaaattgag tgaacgactg aaagcggaaa gagataaaaa ttactttaat
    14941 ttcactcttt cagatgcatt tccaaataat cacgaaggat tcgggcatga ttataaaccg
    15001 gttctttgga tgcataaagc aaagtgatca ccggatgagg tttgataaga gtcagaaaat
    15061 cggcaacagc ttgagaagct tccagttcct tctgatacat tacgacaaaa tcattccagt
    15121 gacccggaat atcttcatga aaccatctgc gcagtgctgc ggaaggcgtt atatcttttg
    15181 cccagtaatc atatttcaac cattcttttt tgattccacg tggccagagt ttatctacca
    15241 gcacccgata tccgtcggtc tctgaaaagt cttcgtacac tcgctttatc ctaacttgca
    15301 ccatttccgt ttatatttag ttatcataag aataaaccga taaaacggaa aattgtttat
    15361 cgaaaaagcc aaaatcaacc taaggattcc tgcgtttttt taaattcgta aggagtcata
    15421 ccagtctttt cttgaacata ctgtacagaa taggcgtact attaaatccg gcttcatcag
    15481 ctatcgcacg aatggtataa ttgggatgtt gcttcaataa ctgaatcgca tagttaatac
    15541 gaagttcatt aatatacccg ttgaaattag ttccggtgtt ttccttgatc atccgggcga
    15601 aacgcgcatt attcaaatgt acaatctgag ccagatcctc tctcgacaat tccggagaca
    15661 gatataactg atcctgaaca acaatacgat tcagttcttt gaaaattttc ttattctcat
    15721 cctcttcctc cctactctcc actacttcat ccggagataa atcgtctttt tcggaaaagc
    15781 cagtttccgg ttccaagtcc aatggaacag ctatcggatc ttccgcatct ccatctatga
    15841 ataattgttt gttctctact tttccagcca gtttctcatt gataaacttt gccagcattt
    15901 tgtttttata tttaacaata atcgtatgac gccaaatccg ccatagcaca aataaaatga
    15961 gacaagtgac acatcccaaa aaagcaagtg atatgtttct gattcttaac tgtaaagtct
    16021 gttcggcaat atattcttcc tgctcgtcag ctttatgaat agcatttaat tccaaagccg
    16081 cattctgctt atccttgctg ttaataccat taataataga aataatagac tcacgtaatg
    16141 ctgctacttt ttcaaaatcc ttcaagcctt tataagcttt cacctctttc tgaaggatac
    16201 taatatactg caagttgaca gtatcctgct cttgcatcaa tttcttaaaa tcctgacatt
    16261 gatcaacgac tttctgatat tgtttagaca ctagcagata aggtatcgca taggtttttc
    16321 catccggtgt ctgtgaattc tctgttgaca aatattgttg ataatatttt tccgcctgat
    16381 catactttcc ttccagatag cagatatacg acatttttgc atacaagtaa gtatattgca
    16441 gatcaagaaa gccttttgtt ttttccggta atttagctat atctttaagt agcttttcgc
    16501 gcttcaaccc aacctccaat gcttctttac tacgggaatc attgagcaga taatccattt
    16561 tcatcccata aaagtatgaa agcatagcca tttccaattt ggaacttgta ccttgaagca
    16621 atttgatagc tttgtcaaaa tagtcatatg cctcctcttt gaaagacaat tgccatttat
    16681 tttcaccaat gcaaaacaac agcttacttt cagccccttt atccttttct ttttgtgcta
    16741 gcttgatacc atcaagagca tacctcatac tctctttatg gtcactcata agcactgcta
    16801 attctgccag gtcgacagtc atggtcaaca agtgcttagg atctttctga gaaacggaat
    16861 ccagcaaata agactttttg gcatacaaaa aagccagttt agtcatatac atattacgat
    16921 aaaccctgct gcgtaattca tgtataatac gcagagggat agtcttctta ctttcagctc
    16981 catccaacaa acttaaagcc cgttcaggtt ctgccatata aattcgactt atatactcac
    17041 tggtatatag cgaatcattc tctatagttt tgtcggcgaa aaggagctgg ttaaacacaa
    17101 acaaaaacaa acaaaaacaa ataaccgagc gaatactttt cattataatc ccaatgattt
    17161 tactccccaa aagtaaaaca tagtttcata aaatgcaaga attgaacata tttgaatgaa
    17221 ctaaaataag aaaagttagt gattataaaa gtcaagagcc atcaagtctt ccccaccaac
    17281 cacatacaat aaaatactaa aaatcaagca tatgtcacat acataaaaca aaacatctca
    17341 acatacaaat aaactgccga ttctattaag gaatctgcat aagatcagag cagcacatga
    17401 aaaatcgaac cgaccagtct aaataaacac cagacaatta ttaacccgcc acactcatca
    17461 gagcaaaaca gcacaaaaac agaaaatcaa aaaagagaaa cacatactgt aataagaaag
    17521 attataatcc caacgcttta tcaaaccgtt gctccataca tgcactcaaa tccgtcgtta
    17581 caaactttcc tttatagaaa agagaaaaga tagtagcagg tgtaggtgca ttttgtgctt
    17641 gtgccatcgt ttccaatctg actatcttca atggaatacc tttgttctca gtcacaccca
    17701 ctaaagaatt acggacatga aactctgcaa acggacaacg atgtgtataa taaacgacta
    17761 caccttcttt ttcctcacat tctccacttg atactgttcc attgaatgac ggatcaggag
    17821 ctgccggatt tatcttcaaa gccaaaagac tgaaaccata gggtagtttt tctatcgtct
    17881 caaacccctg acgtaataac catttcgcat cacccataaa atgaaattta gaggtaccga
    17941 ccacagtcac caagccatcc ctaccctgtg ctttggcatc ctcgacagca gactgtaata
    18001 gtgctttgcc atgcccgcat cctttatatt ttcctgaaac ccaaaaacag tttatcatta
    18061 aatagttagg tgcattaacc ggaacccaag ctttttcggc aggcccatat tctataaata
    18121 cttttgcacg ttcgtcaagc cgtctgaaaa catagccatt ctcaaactca tttttcagcc
    18181 atgtcttttt caactcatag ctatccttgc atttcttatc ggagaaagca cagcaaatat
    18241 gttctttttc gatattctct ttagtcagag tgatatactt cgcttccata atattctgtt
    18301 tattagtata taaattccgg ttgtccattt taactacagc aaagatacac aatcgaaagt
    18361 aataaaacat tgtccagtct cgtcaaaatg acacagtagt acggattaaa gttcggaaaa
    18421 cagataagta aataaacctg agtgacaaac ttatcaaaga acttattgac cactctgtgg
    18481 aagaagtgat caaaaaactc cctaagaaaa aacaggagga atatcgcaca atgatttaac
    18541 ataaagcgtg aaaccgctga ctggtaacca tacaaatatc cggctttgct gcaattcaca
    18601 atagtaaagc cggatattta actgttaaaa gcatatatcc catataccac aagcactttc
    18661 caatgctact agtgaagcgg catatccttt cattgtttcc agatactcct gttgcacttc
    18721 attataagta cgctgggcaa ccagtacatc aagaatactc gtttctcccc gtttgtattt
    18781 atataccatt ccgtcgagca ccttctgcga gtcttcaagt acaccggctt tatattgagc
    18841 tatctttttc ttttcagcct catagttgaa ccaggcctgg gttatctctg cctgtatctg
    18901 caattccata tctctttcca ttatctccga ttgggcaatc cgaaactttg cagcttttac
    18961 agctccttta tttatattcg agaatgtcag aggaacagat acaccggcag tagcagaacg
    19021 ggacggagga agaaagccgt tccagtttct ttcataagaa acagatactc cgatatcggg
    19081 tctgcgttcc gctctcgtca gtttatattc ccgggtagta acttcagtac ttttttgagc
    19141 aacaagcagg tcgatgcgat tatccagtcc cgctttgacc aaatcagaca gagcaaagtc
    19201 cctgcttagc tcttcccaat ttcccaaagg gatatgaagc gtatcagcac tcatccccat
    19261 gtgtttattc aacaaaacca aagcggaatg ataagccgcc tcctgactgt aaacagtatt
    19321 aagcaaggtg acagcttcca gttttgactg ccggacatca ttctccgtaa tctctcccga
    19381 aacataacgt aaactatctg actgactcag ctgatacata tactcataag aacttttctg
    19441 tacttcaagt aattcgcgct gaagaattgc ttctagaaaa aggtcggcag cctccgccct
    19501 caaatcctga aagccctgtt gcaggaccag tttctccaat tctgcctgag tccgcgccaa
    19561 cttaatacgt gctccccttt tatttcccat ttctaatgaa taggaaactc ccaacgagaa
    19621 agtctcatta cctgcttcaa attccaactc cggatccgga aagattttcc gggcaattac
    19681 ttccgcatca gcaatactca cattgagttt ttcggctaaa taactcaggt tctttttcgc
    19741 tacccgattc agatattctt cgaaagaaat agactgcccc agctttattt caggcatttg
    19801 cgcaaaagcc ggaatgagta cggcttccac cattaacagc aagagcacta tattatatcg
    19861 tatattcttt ttcatcgttc ttctttttat ttaaaacatt gttctcaacc agataataga
    19921 aagccggaag cagaaacata gagataaggg ttgaaaacat caatccatac acaatcactg
    19981 ttgccagcgg acgctgtacg tcactaccga ttccggttgc caacgaagcc gggaaaagtc
    20041 cgagtatcgt agtgatcgaa gtcatcagaa taggtcggaa acgctggcgt gccccttcta
    20101 tgaccgattt ccggagttcc attcctcccc tgcgcagccc attgacctgc gataccatga
    20161 taattccatt ttgtatggaa agcccgaaca tcgctataaa tcctacggca gaagatacat
    20221 tcagcgtcat accacgcaca ttaagagcaa gcatacctcc gaaaagtgcc agaggaacaa
    20281 tagccaatac cagtcctgcc tgccggaact tcccgaacgt gacataaagc agtataaaca
    20341 tccctgtcag tgtcagcggt ataatgacag caagacgtgt ataagcccgt ttttgatttt
    20401 cgaaggcccc tccccatttg atggtatatt tattcttgtc ataatgtact ttctcattga
    20461 tcgtattctg ggcttcattc agaaaagatg tcaggtcacg accgcgcaaa ttcagcttta
    20521 ccgtcaaatg gcgtctgttc atttccctgg taatcgtact ttcgccgaca ctcaatctga
    20581 catcggcaac ctgagaaaga ggtatctttg caccggtgga agaagtcaac ataagtccgg
    20641 ctattttctc cggagtattc cgcgcttcct ctttatactt acaggtgatg ccatactggc
    20701 ggtcaccctg ataaagttgt gcgatagctt tacctccgac agccacttca atcagatccg
    20761 ctacatcgga tacatttaat ccgtaacggg ctatggcatc acgattcata ctgatctgta
    20821 actgtggcaa gggtggttcc tgatcaatat ccagatcaac agcccctcgc acagttccta
    20881 atgccctggt tatttcttcg gcaatacgac gtgtttcacg aaaatcttcg ccatatactt
    20941 tcaccaccag ttcactatgg gccccggcta tcttatccat caccccgtct atcataggtt
    21001 ggctaaatcc tactttaaaa ccgggaagta acttatattc ttcttccagt tcatgaatca
    21061 aatccttttt agtttttcct ttcggccatt catcataagg cttaataccg atggacactt
    21121 caaaatgtga aggggtgaac ggatcagttc cgtcgtcatt ccttcccgcc tgtaccataa
    21181 tataagttac ttcggaatac ttcatcgtac gggcacgcaa agtatcggat aactcccgtg
    21241 acttttctac ggaaattccg ggtggcagat taacctgtaa ccatatcgaa ccttcatcta
    21301 gctccggaag gaagtctttt cctacgacaa cactcaacac gatccccgct gtcagaatca
    21361 gtcctgatgg aatgatggct tttaagggag cttccagaaa tcttgtaatg gtacgaatgt
    21421 atttatcctt tagtctgtcc agccatttat tcttatatat tttatgtggt ttacgataga
    21481 ttgcataggc aagtcccgga atcaataaga gcgcaaccaa cagtgctcca atcattgcat
    21541 agctcatcgt aaatgccatt ggagtaaaaa gtttgcgttc aacacgttca aaggcaaaca
    21601 gcggaaggta tgccgtaata atgacaatgg ttgagaaaag aataggccga cccacttctt
    21661 tggcgcgttg cgccatgctt ttttcttcga gatattgttt gggattatcc tcacgtttct
    21721 taaggatcgt ttccagcata acgatagcac cgtccacaat aataccgaaa tcaatagcac
    21781 caagcgacag aaggttagcc ggaatatccg tcagatgcat aagaataaaa gcgataagca
    21841 atgacacagg aatcgttata gataccaata atgcaccacg ccagttgcct agaaacagaa
    21901 taagcacaag aaccaccaaa gccataccca tcagcaaggt atgggatacg gtactcaaag
    21961 tagtatccac caagttggta cgatccagaa aagtatgtat cctcactcct tccggcaatg
    22021 tctcattatt taactcatca actgccacat gaatatcttc cagtacttta gacggattct
    22081 catgtttcag aaggagtaca attccttcca gactctcaga gtagttgcgg gtacggtccg
    22141 tatatcccag cactcccttt ctttcaagat ttccatactt caaagaacct atatcattca
    22201 gaaagacagg aactccggaa gtagtactca ctacaatatg tcccaaatcg tccaaatttc
    22261 cgattaatcc aattccccgt accacataac ccaagtcacc acgattcaac acgcttcccc
    22321 ccacattggc attgttattc tcaatggctt caacaacctg gctgagagat aaattatatt
    22381 gttccagttt ggacggatct acttcaacct ggaactgagt agtgatccca ccgaaattgg
    22441 ttacatcagc cactcccgac acttccttga tacggggaat aattacccag ttctgaaggt
    22501 cggttaattc gcgtaatgag tgctggtcac tttctatgat ataacggtac acttctccta
    22561 cgggagatgt cagcggatca agtcccggaa cagctccata aggcagttct acttcattca
    22621 atctttcctg tacgcgctgg cggctccagt agtcctctgt cccgtcctta aagacaatgg
    22681 taatcattga cagcccgaat gtactcttac tccgcatgac gtgcataccg ggcagcccat
    22741 taatagcgcg ttccaaagga atggttatct gctgttccac ttcctccgca gccagtccgg
    22801 gaacttgagt gaccacctgg gaagtgacat ctgcaatatc cggatatgct tctatcgaaa
    22861 gctgtttcca tgagtaatat ccaaagatac acatcatcac aaacaggcaa agcattaccc
    22921 atcttttttg tataattgaa agcattaatt ccttcttcat aatttcttac tttaaataat
    22981 atcctccttc actgattatc ttatctccgg gacgcaatcc ttcgctgatc accgctattc
    23041 cgttttctgt tgtctccact gtcaccgacg tccgtacgaa aaccaacgga gcaatctgca
    23101 caaatacata gctatccttt tcgccctgca gtaacgcttt ctccgggatt tgaatttgtc
    23161 tgaccggaac actcagaaag tggacagtag tgtacatccc cagcttcaga tgtccgttca
    23221 aattatcaca gatcgaaagt acctgaatgg accgggtttc ctcgtctacc tcctcctcta
    23281 catgatacac attgccttta ataaccgtac cgggcaatgc cgaaatttca atatccagat
    23341 tactgccttc atttataaac cggatatctt tctcctttac ctgagccgca atccatacct
    23401 tagacaggtc ggcaacaata gctatcggtt cggtatcgtc tttcagatat tgccctgtta
    23461 cgatattatc ctttatcact tccccgggaa taggagaacg aacaatcatc ggttgcccca
    23521 atatcatttc cgccagattg tccacctgat atacccgcaa tgcggcagag gcgttttcaa
    23581 actccttatc tgctatcaat aaagcattct gggcttcttc cagttctctt tgcgaactga
    23641 caccattcct tatcagatct tctttgcgtt tcaaatcttt tttagcaagt tccctggacg
    23701 aaagtgcctg aaagtattcc ttttgtgcag aagtaaagtc gggggaactg atttcaaata
    23761 aaggtgttcc ctgacgtacc gactgtccga tacgcacata agattttgtg actctccctg
    23821 caaatggagg agcaacataa gcataacggg gaggaatggg acgcaccaca ccggacgtta
    23881 tcaccttctt ggaatagggt ttcagttcag acactgatac tttgattttt tcaagtaaaa
    23941 gaggatctgc aatatagacc gtgtcacctt gtatacgata gccacttttt tgctctgatt
    24001 cctgtttatc cccgcatgcg gtaaaaaaca acacactgcc aataataaat gtgtgtaact
    24061 ctctcttcat catcataatt aaacataagt taagttagta accggatttc cgggcacaaa
    24121 gatagacggc tcccttcgga gagcctgtta gagaatagtt agaatcctat tagaatctta
    24181 ttagagtaaa taaagatttc ttcttaaaac agcagttttg ttgttagaga gtacgcacaa
    24241 ataaggggtt gactaaaaag ccaacccctc aacggatgat attccggtat ttttatcgta
    24301 agccgaaaag ttcttattct ttcacacaac gtatactttg agcaaaacct tgatatgaca
    24361 atctgaaatt atgagaatta tatgcagact caagcgacca ggctccataa cgtattctcc
    24421 tgtcataagg tggattctgc aattccgatc tcatataagg aggacctaca cttgccgacc
    24481 aatagtatcc ggtactaccc ctactttcca aagcaccact tgtgttattc agacgaccgg
    24541 ctgacggaaa aaagacagat gcattcgttc cggaatcggg attaaaatac aatactccct
    24601 gataagcaac attactattt cctaatgata cgccatagtt tccattcgaa gcctctttta
    24661 tcggacgtct gtcgaaaaat ccgtccgaat aaaatgtata agttgttcct tttagttgtt
    24721 tccgggcaag catatctttg tttgctccgt aaggatatgt cccaggacct gtattaccag
    24781 ttccaccaaa aggagtagta aaagctgtag cgtagtctgc acttgaagcc gcatttcctg
    24841 caaaaggtac attaaat
//
