LOCUS       c00004_gnlPro..        24557 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|AJOIIJFL_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 12:46:35
            Original ID  :: gnl|Prokka|AJOIIJFL_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 1068302
            Orig. end    :: 1092859
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24557
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[1078302:1082859]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14557
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24557
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24557
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="3"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             435..629
                     /locus_tag="ctg4_1025"
                     /transl_table=11
                     /translation="MKKTELALLYMPYASADVARRHLNKCIRRNRELLEALEATGWAFW
                     IHWLTPLQVELIEKYLGEP"
     CDS             complement(920..2719)
                     /locus_tag="ctg4_1026"
                     /transl_table=11
                     /translation="MDRFKELGIDTHGRTSGKMKTKCPWCHAQRTDKRDKSLSVNLDTK
                     LYLCHYCGAHGSAAIYAGKGRKLGDPLVKFPTATGSNSSCPPTEKPHGDPEQGALTQKQ
                     IEWCRDVRHIPPEVLVEAGVAFASISMPISGKEKGWEKRDCLCFNFFENGELVNTKFRD
                     SQKHFKLLQGARTIPYNIDAIRDTPECILVEGEFDALSYMAVGRTDVISVPNGANSQLD
                     WLDELSESHFEQKQVIYLSVDTDRKGRELCRELSRRLGVDRCRIVTYGEAYKDANELLV
                     AEGPDALLKALEDAPIPRLEGTFTAEDLRERLHQLFEEGYTSGVELGIPNLDEIMRLET
                     GRVLTVTGIPGHGKSDFVDEIVLRLCTRQDWRAGYFSPENTPIEYHHAKLAEKLLGHRF
                     RKDFSTEEEFARVVDYLSQRVWHILPDGDFTLGNVLSKARELVHRHGIRVFVIDPYNYI
                     NHQIPAGMTETGYIGSFMNSLARFARLNSCLVILVAHPRKMNKQYGTQKTEVPTMYDIN
                     GSANFFNMTDYGIVVDRQDEMGIVYIHVEKTRFRNFGTKGNAAFCYDVTNGRYSPCTPP
                     PEPGMQVQPWKGAKDLFSSEGWI"
     CDS             complement(2748..3401)
                     /locus_tag="ctg4_1027"
                     /transl_table=11
                     /translation="MKKKRNTKPHVNNSLKANGNAEDFNTREIKKTSNIQKNPSPIINK
                     EINKKIPSSEESGKEKEEENGLKVTDLNAVTPDMRPNAWEENLQEAMNDTSWYEVVAIQ
                     SGIPRLMMEEKEWFFNYLREQIILRGNESSMNSLHEIKNYFANLTRQGSHVSSTTQVAL
                     KKFLKNRQEQQQCSPYETITNGIRTYDGHPIPAYAKPRPSAAHIWNPVTNEWTR"
     CDS             complement(3364..4053)
                     /locus_tag="ctg4_1028"
                     /transl_table=11
                     /translation="MTTSNSANTKQSNNASQKRKPIHNGYFNHPTSSSSNIPMSILIRE
                     QGLEIYGLYWVMLEEAHAQLKCCVNIQTMGIIANIFHAQPEHLELLYHHYFRRPGKGYN
                     SHILYADFCEESAIRSYFPHPLLAYTDNELLRMIMQDGLKAYGLYWLVMEKLYQQPQHF
                     LAPQTASFIQNLYDVSDELMESVLYNYGLFYLDEKMNLHSKAIDDYREALDNMEDEKKA
                     QHETARQ"
     CDS             complement(4392..4745)
                     /locus_tag="ctg4_1029"
                     /transl_table=11
                     /translation="MKNDSCLTVSRRAAIIRQDAEENYGTLLTLGESMRRAYQVEELID
                     RMRWDNADFCLQRTDGTCLSITGTLTEHEHYFGRPYYENPSNRFLPYYDVHCRKWLTCR
                     VAGIVFGSSVKKN"
     CDS             complement(5065..5496)
                     /locus_tag="ctg4_1030"
                     /transl_table=11
                     /translation="MPKWISVEKAVIKYHIEKEAILLWVEMGQFPMLYIDNVPNVDEEC
                     ILELFRRSKAGITAEYIDTLEQLCIDKTMVCEKYAHIIQLKEKEIQLQKEINTLINEIQ
                     AAMKRQNERIRDLKKAIGENNNVIRSDSWIKRLRKRFQW"
     CDS             complement(6228..6635)
                     /locus_tag="ctg4_1031"
                     /transl_table=11
                     /translation="MEITDLKQMTKEEVFNFIRQRLSFSKELQEQFRHVNKDALAKEHR
                     RFEMSGNESKTGQCTIFNTAILNEFADLGIYDYTSYLFLDFHNGTPTVYLKYFSENENL
                     EYTFTGYTTTEIIFAILELTIFSGKPKRNRS"
     CDS             6829..8043
                     /locus_tag="ctg4_1032"
                     /transl_table=11
                     /translation="MINREQYMEQIVPFIDKPFVKVITGIRRSGKSVVLRLIRDELLRR
                     GVREERIIYLNFESFQWIDLKEAKALYAYIRGQAGDAGKYYILLDEIQEVDGWEKVVNS
                     LLVDLDTDIYVAGSNSRMLSSELATYLTGRYVAFHVMTLSFREYLTFHDLQANDPTLNR
                     KEEFQKYLRMGGFPAIHTADYGYEAIYKIVYDIYSSVILRDTVQRHNIRNVELLERVVK
                     FVFDNIGNKLNAKNIADYFKSQQRKVDMNTIYNYLNALESAFIIQRIPRYDIKGKEILQ
                     TNEKYFVSDLSLIYSVMGYRDRLIAGMLENLVCLELKRRGYEVYVGKQDDKEVDFVAIR
                     REEKIYVQVTYQLASQATVEREFAPLLAINDHYPKYVVSMDNLWQDNVEGVRHRHIADF
                     LLDDA"
     CDS             complement(8124..8378)
                     /locus_tag="ctg4_1033"
                     /transl_table=11
                     /translation="MKKGLHPKSYRPVVFKDMSNGDMFLSRSTVATKETIEFEGETYPL
                     LKIEISNTSHPFYTGKSTLVDTAGRVDKFMSRYGDRKKK"
     CDS             8812..9816
                     /locus_tag="ctg4_1034"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAVRKVFAEKPAEFDPRKYLGPARDNMEKLYKHKIINVLGSDNKLAQ"
     CDS             complement(10001..11161)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1035"
                     /sec_met_domain="OAD_beta (E-value: 8.1e-152, bitscore:
                     501.6, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATVGHVVMILVGLVFIYLAIAK
                     EFEPMLLIPIGFGILIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKNERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFVIATASGVIFVKIFNIFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDSTNYLLMHAMGPNVAGVIGSAVAAGILLGFLM"
     CDS             complement(11163..11594)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.7; E-value:
                     2e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1036"
                     /sec_met_domain="Biotin_lipoyl (E-value: 4.6e-20, bitscore:
                     67.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKPV
                     AKPVTVRPMPNAPAAPTQVVKPTAPSTGKSGVKSPLPGVILDIKVNVGDTVKKGQTIII
                     LEAMKMENNINADKDGKITAINVNKGDSVLEGNDLVIIE"
     CDS             complement(11619..12539)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1037"
                     /sec_met_domain="OAD_gamma (E-value: 7.9e-14, bitscore:
                     48.5, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLVLNEILIDNQSNFQD
                     DYGLHSAWIEIFNKSFGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWVGLFDSGKKLLDQIVVPAGALGPNQSYARVSDGAAEW
                     EVKSGSGDKYVTPSTNNKTLDSNSKMEKFEEHDADGVGMSISAMSVVFCGLILLFIAFK
                     IVGKVAVNLSKRNAMKSKGIDKHEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLT
                     ITRVKRSYSPWSSKIYTLRETPPRK"
     CDS             complement(12571..14124)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1038"
                     /sec_met_domain="CT_Btheta (E-value: 2.3e-288, bitscore:
                     953.0, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERLAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYVFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFGPCAGGAVYSPALTDFTLMMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHST
                     KSGVTHFTAQTEEEGFELIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPT
                     KPYDMYEVIGAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNA
                     SRKGARFVRFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTI
                     TLRKSYGGSHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLA
                     EKEAEYTKLFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL
                     "
     CDS             complement(14153..14557)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_1039"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.5e-22, bitscore:
                     76.4, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAESKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             complement(14733..15731)
                     /locus_tag="ctg4_1040"
                     /transl_table=11
                     /translation="MPLKLTTYYHGKDIPELPGKNAFHSKELFQIYEATPGYTPLLIVA
                     TEDGRPVARLLAAIRKAKKWLPSSLVKHCVVYSEGEFLDESLSTNKEKAEEVFGDMLEH
                     LTQEASRSCVLIEFRNLNNSMFGYRVFRANDYFPVNWLRVRNSLHSMKKTEDRFSPSRI
                     RQIKKGLKNGAKVEEAHTVEEIHDFSRMLHKVYSSRIRRYFPANDFFRHMNDMLIKGQQ
                     AKIFVVKYKEKIIGGSVCIYSGDDAYLWFSGGMKKTYALQYPGVLAVWKALEDARQRGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRVNWNWLNKLLVKFYV"
     CDS             15971..17062
                     /locus_tag="ctg4_1041"
                     /transl_table=11
                     /translation="MRCNAFVEAWKNYHRRASMILGLSLLAAPLSYAVYAEDGVSNTMV
                     QVVTQTKTVKGTIIDESGEPLIGVSIVVKGTSTGTITDFNGNFSIDLPAGRKELVISYI
                     GYKEQTVTVTGNGPVNVKMVSDTQALDEVVVVGYGTMKKRDLTGAITSVKSEDVVMNPS
                     SNPMQALQGKVAGLDITRESGQAGSGVKMQLRGNRSFQKDSGNPLFIIDGMPGDYSTLN
                     PNDIESIEVLKDASSTAIYGSSGANGVILITTKGGKEGKAIVNFNAYVGVNGWSRTPEM
                     RSGESYIQTLRDASVGAGDGRWSSVADDKNLFTTDAEWSAHQNGQYIDWVDALLKTSVT
                     QNYSVSVAGGTEKTKAYFFSELL"
     CDS             17142..19211
                     /locus_tag="ctg4_1042"
                     /transl_table=11
                     /translation="MKVGIDAQLSYVHQNKADSDLQTLMASNPLGSLYNEDGSINPQPV
                     ADPSSTVYNYLLNEDKSLYRNQAQNLKVYFNPYLEITPLKGLTFITRAGASLGYSRSNT
                     FTGEGSVQWYKANQTADGIKAQVKDNRSYNYKWENILTYNFQIKKVHDITLTAVTSWNH
                     NRSDVTTLYQKGVSDNKFLWHNILDGNSATSGSTSYSMSKGMGYVGRLNYSYMGRYLFA
                     ASVRHDGSSRLAEGNKWDTFPAFSLGWRISDEKFMESTTNWLSNLKIRFGYGVTGSTAG
                     IDPYSSAASLDATAVNMILGGVLTPIYKFSQNIPNYLLTWEKSYNTNIGIDAAFLNNRI
                     DVSMEYYNTKTKDVIWNKALPVINGAFSPDGGPKANYTTNLNMCETSNKGFELALNTRN
                     IITKNFIWSSSVTFNHNKEKITKLSGGDSDVLNNGDTGYALALGEAINSYYHYKLDGVW
                     QKGEETDAAVFGAAPGDLKINIPNLVKESDGRFYKIDEETGSAAVDENGNVIYYTSDNK
                     YTPSDADYQILGHNSPDWSLGFQNNFTWKDFDLSVFVYARYGQMFAYDMLTSYDPKGIR
                     NFPTYFNYWTENNPSNDFPAANANKGLEQYTGYYALRYVDGSFIKIKNITLGYSLPKSI
                     LKSAGIEKCRFYATITNPFVFAKSHLLKDYDPEMNGSLKYPLTKQFVFGVNVTF"
     CDS             19235..21259
                     /locus_tag="ctg4_1043"
                     /transl_table=11
                     /translation="MKSTIYKIAALTFAVASMSACSLDEYNPSQKTGDEILATFDGLKG
                     LQSYCYSSLYGQLFSVYDFLSVAEGGTDCWITPAGNPDYAKQVIYYDGLATNTNATNKL
                     FGQAYSMIGNCNAVVNRAELLTDGNEKDITTLVAEARCLRAFYYSILVNTYGNVTLTLE
                     ESSQDPILTPQRNSIEELYTQIIDDLKFAANNLEDTPYDNNRARVTKKTALGLLARVYA
                     QGGGEYGLTEEGVSYWQRAKEVAEDMILAYGDCLYDDVEDVWAPANNRNNKEALFIAAG
                     PDATNLENWNAGTQCNNNFTYMYPKPNTLTIYPTPDNQNYWYGRTNNNTLAPSKYLLDC
                     FDADYDKRWEVTFTTAFVQFSAVQSGGSYLFTNKKQTLDDGTKPKIGTKHGVNDNISSF
                     TILTQNIIDTYGLDAKFHNEYIYPYGDLNYTYYDGTWAPKMIAKVWPKGENSGDPSKLQ
                     EVKNPYVIPYPVAEDDDRICFYLSKERLSDAEKAKRRYYVINIDDLFDNGQYRKTDIKV
                     TNDKNMYPGFNKYNWLSEDSYSSNLQRKTGDVFIMRMAEVYLIAAEANQQLGNGGKAAE
                     YLNVLKKRAARNDASYNAMKLSNATQNDVMDEYARELCGEYQRWVLMKRHKDSFKQRLA
                     VGNPRAAENFDENKHYLRPISFNFLSQIDNAEEYGNNGY"
     CDS             21366..21908
                     /locus_tag="ctg4_1044"
                     /transl_table=11
                     /translation="MLEEILAYNKQFVENKGYESYITNKYPDKKIAILSCMDTRLTALL
                     PAALGIKNGDVKMIKNAGGVISHPFGSVIRSLLVAIFELGVEEIMVIAHSDCGACHMHS
                     EVMLEKMKARGINPDYIDMMRFCGVDFHSWLDGFEDTEKSVRGTVDFIVRHPLIPSDVT
                     VYGFIIDSTTGELTRIV"
     CDS             22162..23619
                     /locus_tag="ctg4_1045"
                     /transl_table=11
                     /translation="MVKIQKISEIEPCLGFTEFDMLKKYRQSFATSELGRLHSLFPFSE
                     LARQMHLKSSPFGRKSYFSPEGKIALMVLKSYTNFSDAQLIEHLNGNIHYQLFCGVQID
                     PLHPLTNPKIVSAIRQELADRLDVESLQLILAEHWTPYLENLHVCMTDATCYESHLRFP
                     TDTKLLWEGIVWLHRHLCKHCQTLHIQRPRNKYLDVRRAYLAYSKLRKRKKSQTRMITR
                     RLLQLLEKLLDQLELLHSSYRNRLTLSSDYQRRFSVIQTVLEQGKNLFAGKKVSNRIVS
                     IDRHYLRPIIRGKETKSVEFGAKVNNIQIDGISFIEHISFKAFNEGVRLKDCIHLQQQL
                     TGVRVKALAADSIYANNANRKFCTKYHISTSFKRKGRAAKDEPLRKILRSELSRERATR
                     LEGSFGTQKQHYSLARIKARNRKTEVLWIFFGIHTANAVCMIEKVEKKKERQHNLTKIT
                     GKTGEVLTSPKKDMYIMHGWEGKNKNM"
     CDS             complement(23729..23941)
                     /locus_tag="ctg4_1046"
                     /transl_table=11
                     /translation="MKKRITQDDYVKANRKASREAEIEMYGHPICHKRVHQSKKVYNRR
                     KIKAADKKLPYFFVFKIASLSWDIQ"
ORIGIN
        1 gagcaactgc tcgcgcatca ctgccatcag gtttcggatc acgttgtgca cgtcaccggc
       61 cgtcagtgat gaccgttcgg caatcgtttc gccaatcatt tgcgtatcca ctacgtttcc
      121 cattttaatc aggcagggat gccatttctt ctttttgtcc ttcgatgcga tattggactg
      181 aaccgctttg taaatcaaca tactgatttc ctccttttta agtgaataaa taagatttta
      241 ttgagtcagt aaacgaacgt tttctgtctc ttttacagta gcaaagatac cccaaccggc
      301 aggggaggaa acatgaaacg gtatctgccg gtaagtgaag gcaaacgctt gaatatctgt
      361 gtatttgctt gcatttctac gcaaaaaaca gtatctttac atgacgtaaa taataaatta
      421 aaagaagaaa atctatgaag aaaacggaat tggcattact ctatatgccg tatgcaagtg
      481 ccgatgtggc aagaagacat ttaaataaat gcatccgccg aaaccgggag ctgctggagg
      541 ctctcgaagc taccggctgg gcgttttgga tacattggct cacaccgttg caggtggagc
      601 tgattgagaa gtatttggga gagccttaat ccctgttttt gatctcccaa aaaccattac
      661 gacgaccgtt tttacgctct atgatgcccc tttcgctcaa gttgacagtc atggttttaa
      721 cggttctttc agactttcct atatgctggg caatttcttt ttgtgttgca ttaggttttt
      781 cttgaaggta tttcagtacg gccatttctt ccaaagtgca atccaaagtg caatttttgc
      841 actttggatt ttctgtctct gtttgttttg cactttgagt agcttgcttt tcaagttatt
      901 cttgtagcag ccttaatccc taaatccatc cctctgacga gaataagtct ttggctcctt
      961 tccacggttg cacctgcatg cccggttcgg gtggcggcgt acaaggggaa tatcttccgt
     1021 tggtcacatc gtagcagaac gctgcgtttc cctttgttcc gaaattacgg aaacgggttt
     1081 tctcgacatg tatatacacg atccccattt catcctgacg gtctaccact attccgtagt
     1141 ccgtcatgtt gaaaaagttg gccgagccgt tgatgtcata catggtggga acttccgttt
     1201 tctgcgtgcc gtattgcttg ttcatctttc tcggatgcgc caccagaatg acgaggcagg
     1261 agttgagccg ggcaaaacgt gccagactat tcatgaatga accgatatac cctgtctccg
     1321 tcatgcctgc cggaatctga tggttgatgt aattgtacgg gtcgatgaca aacacacgga
     1381 tgccgtgacg gtgtaccagt tcgcgtgcct tcgacaagac gttgcccagt gtgaaatccc
     1441 cgtccggaag aatgtgccag acgcgttgcg aaagataatc cactacgcgg gcgaattcct
     1501 cctccgtaga gaaatctttg cggaaacggt gtcccagcag tttctccgcc agtttggcat
     1561 gatgatactc gattggcgtg ttctccggac tgaaatatcc cgctcgccaa tcttggcggg
     1621 tgcagagccg gagcactatc tcatccacaa agtccgattt gccgtgtccg ggaataccgg
     1681 tgacggtgag cacccgcccc gtttccagcc tcatgatttc gtccagattc ggtattccca
     1741 attccacgcc cgaagtatac ccctcttcaa acagttggtg caaccgctcc cgtaagtctt
     1801 ctgccgtaaa cgtaccttcc aggcggggga tgggtgcgtc ctccagtgcc ttcagtagtg
     1861 cgtccgggcc ttccgccacg agcagttcgt tggcgtcctt gtatgcttcg ccgtaggtga
     1921 cgatacggca gcggtctacc cccagccgtc gggagagttc ccggcacagt tcccgtccct
     1981 tgcggtcggt gtccaccgac agataaatca cttgtttctg ctcgaaatga gattccgaca
     2041 attcgtccag ccagtccagt tgactgttgg caccgttcgg cacggaaatg acatccgtcc
     2101 ggccgacagc catgtaggag agggcatcaa attccccttc cacgaggatg cactccggcg
     2161 tgtcgcggat ggcgtcgatg ttgtaaggga tggtgcgcgc tccttgcagt aatttgaaat
     2221 gcttttgtga gtcgcggaac ttcgtgttca ccaattcccc gttttcgaaa aagttgaagc
     2281 agagacagtc cctcttttcc cagcctttct cctttccgga tataggcatc gagatggagg
     2341 cgaaagccac gccagcttcc accaatactt ccggcggaat gtggcggacg tcacgacacc
     2401 attcaatttg cttctgtgtg agtgcccctt gctctgggtc gccgtgcggc ttttcagtgg
     2461 gcggacaact ggagttgcta cctgttgccg ttggaaattt gaccaacgga tcacccagct
     2521 ttctgccttt tccggcatat atggctgccg aaccgtgtgc gccgcagtag tggcacaaat
     2581 acagtttggt atcgaggttg acacttagtg atttatcacg cttatccgtc cgttgggcat
     2641 gacaccaggg acattttgtt ttcattttgc cgcttgtgcg accgtgggta tcaataccca
     2701 gttctttgaa tctatccata tttagtaaat gattgagaga taatatgcta tcgtgtccat
     2761 tcgttcgtca ccggattcca gatatgtgcc gccgaaggtc gcggcttggc ataagcgggg
     2821 atgggatgcc cgtcgtaggt acgtattccg ttggtgatgg tttcgtaggg cgaacattgc
     2881 tgttgctctt gccggttttt gagaaacttc ttcagtgcca cctgcgttgt ggatgacaca
     2941 tggcttccct gccgggtgag attggcgaaa tagtttttta tttcgtgcag gctgttcatc
     3001 gagctttcat tcccccgtaa gatgatttgc tcccgtaaat agttgaagaa ccattctttt
     3061 tcttccatca tcagccgggg gatgcccgac tgaatggcta cgacttcata ccaggacgtg
     3121 tcgttcattg cctcctgtag attttcttcc catgcgttgg ggcgcatatc gggtgtcaca
     3181 gcgttcaagt ccgtcacctt caaaccattt tcttcttctt tttcttttcc gctttcttca
     3241 gaagaaggaa tttttttgtt tatttcttta tttataatgg gggatggatt tttctgtata
     3301 tttgacgttt tttttatttc ccgagtgtta aaatcctctg catttccgtt ggctttcaga
     3361 gagttattga cgtgcggttt cgtgttgcgc ttttttttca tcttccatgt tgtcaagtgc
     3421 ttccctataa tcgtctattg ctttagaatg gaggttcatt ttctcatcca gataaaagag
     3481 tccgtaattg tataatacac tttccatcag ttcgtcgctc acatcataaa ggttctggat
     3541 gaaggaagca gtttgcggtg ccagaaaatg ttgtggctgt tgatagagct tttccatcac
     3601 aagccaatat agtccgtagg ctttcagtcc gtcttgcata atcatccgca gcagttcgtt
     3661 gtcggtgtat gccagtaggg ggtgcggaaa ataacttctg atggcagatt cttcgcaaaa
     3721 gtcggcatag agtatatgcg agttgtatcc tttaccggga cgccggaaat aatggtggta
     3781 gaggagctca agatgttcgg gttgggcatg gaatatattg gcgatgattc ccattgtctg
     3841 gatattgacg cagcatttaa gctgtgcatg agcttcttcg agcatcaccc agtatagtcc
     3901 gtatatttcc agtccttgtt cccgtatcaa aatactcatg ggtatattgc tggaagaaga
     3961 agtgggatga ttgaagtaac cgttatgaat cggttttctc ttttgtgatg cgttgttcga
     4021 ttgtttggta tttgctgaat tagatgttgt cataataaaa tatattagtt tctgttttaa
     4081 attctatttt tctgaaaata cagatacgaa gaatccggcc acttctttgg aaagcagcaa
     4141 atatcgtact cattcttcat gatggaatcg gagtattctc ttcgtgtatg taatctgtaa
     4201 tatagggaat tttcggagca ggggagattt aattccgaag ttctgaaaaa gcaatgcagg
     4261 aaaaacagat aactgcctct gtcaaaaaac aaggaagcag cattgacatg attttttctc
     4321 ttacttgcgg ttgcaaagta actactttat ttcgtatatg tcctacaact ttccttattt
     4381 aatccatgaa attaattttt tttcacagaa gagccgaata caatccctgc cactcgacac
     4441 gtaagccatt ttctacaatg cacgtcatag tatgggagaa acctgttgga ggggttttcg
     4501 tagtaggggc ggccgaaata gtgttcatgt tctgtcagtg tccctgtaat ggaaaggcag
     4561 gttccgtctg ttcgttgcag gcagaaatcg gcgttgtccc atctcatccg gtctatcagt
     4621 tcttctactt ggtatgcacg gcgcatagat tctcccagtg tcaacagtgt gccgtaattc
     4681 tcttccgcat cttggcggat aatagctgcc cgacgggaaa ccgtcaggca actgtcattc
     4741 ttcatcgttt ttttcataca gatttctttg tgctgaaatg ctcacatttc agttcttgtt
     4801 agtggtataa atgtagtgaa tttacttgac tttacaaagg ataaaattac ttatgtaatg
     4861 gatgattagt taaataaatg gaataaaata ttttgtattt ttcattgttt gaatataggc
     4921 tttaaagagc ttatggagga gtttaaagaa agctgtggag ggaatgggaa taggctgcaa
     4981 agggcaaagg acggccctct ttatcctctg tggtgaaaac cgtgcaataa tgtcccacat
     5041 ggtaattggt acactgataa ttattcacca ttgaaacctt ttgcgcagcc tttttatcca
     5101 actgtcacta cgtataacgt tgttattctc tccaatcgct tttttcaaat cccggatccg
     5161 ttcattttgt ctcttcattg ctgcctgtat ttcgtttatc aacgtattta tttccttctg
     5221 cagctgaatt tccttttctt tcaattgaat aatgtgggcg tatttctcgc agaccatcgt
     5281 tttgtctata cacagttgtt ccagcgtatc aatatattct gctgtaatgc cggctttact
     5341 tcggcgaaag agttccagaa tacattcttc gtcaacattc ggaacattgt ctatgtataa
     5401 catagggaat tgtcccattt ccacccaaag caggatcgct tctttttcga tgtgatactt
     5461 aatcactgct ttttctacac taatccattt tggcatatcg cttttgtttt aatgtgttat
     5521 aaaaaaggag taaataacgt attgtccgga gaggtgcaac gaacacccac gatttttatg
     5581 atttcggtcg gctggggaat tggttggggt ataaggattg ttgaaaccga ccggatacaa
     5641 taaaagcgtg agtgctgttg taccattatc taaacttgag gcttagcaac acccttgtag
     5701 aagacaatga taacaacaga cacccacgcc aaacgtttat atataacaca tctctaatcg
     5761 atatgttgat atacgaccat ctacgtggag tatctgctgt atcatctctc tctacaaaga
     5821 actgctaatt ttcaagtttg agagacaata cgttatttac tccattaagg aataaaaacc
     5881 gcttttgcct gtttcatcac gctgatgggc agaaagcgta tgacaaagat atatgttttt
     5941 ttcggaatag gatggaaaag aggaaataaa tgcaggaaat atggtatgag aatagagagt
     6001 atggtataaa gatggtaaat atgctatacg ggtggcaaat ataatgtgat gataaaaagg
     6061 agggagccaa aagtaaaacc atctccaaga ttgatattat ttaggcacgg attacacgag
     6121 tttcacggtt ttagtctaat ggaaccgtga aatccgtgta atccgtgcct aaatgaaagc
     6181 cataaaagtc ttctgacctc gcattgtctt tccgtgcaat tcttttttta gctgcgattt
     6241 cttttgggct ttccggagaa gatagtcagt tcaagaattg caaagatgat ttccgttgtg
     6301 gtatatccgg taaatgtata ttccaaattt tcattttcgg agaagtattt gagataaacg
     6361 gttggagtgc cattgtggaa gtcgagaaaa aggtaagaag tataatcata gatgccaaga
     6421 tcggcaaact cgttcagaat cgctgtgttg aaaatcgtgc attggcctgt ctttgattca
     6481 tttccggaca tttcgaatct gcgatgttct tttgcgagag cgtctttatt cacatgtctg
     6541 aattgttctt gcagttcttt actgaaagaa aggcgttgtc tgatgaaatt aaaaacttct
     6601 tcctttgtca tttgttttaa atcggttatt tccatttttt attaattagt cgggtaaagg
     6661 tactttcttt atttggtaat aaatcggatt tagtcatatt tcttttattt atttttcggc
     6721 ttataaccct aaaagaatct gaatttatgg atttatttag ggttataacc ctaaaaactt
     6781 tccgaaaata gtatatcttt gtgcttataa ccctaaaaac ttttgaatat gattaatcgt
     6841 gaacagtata tggaacaaat tgttcctttt atagataagc cgtttgtgaa agtgataacg
     6901 ggtattcgtc gcagtggaaa gtcggtagtg ctgcgtctga ttcgtgacga actgttgagg
     6961 agaggagttc gtgaagaacg tatcatctat ctgaattttg aaagttttca gtggatagat
     7021 ctgaaagagg cgaaggcttt gtatgcttat attcgggggc aggcaggaga tgcgggtaaa
     7081 tattatattc tcttggatga aattcaggaa gtggacggtt gggaaaaagt ggtcaactca
     7141 cttctggtag atttggatac ggatatttat gtggccggct ccaactcacg tatgttatcg
     7201 tccgaactgg caacttattt aacgggacgg tatgtcgctt tccatgtcat gaccttgtct
     7261 tttagagaat atctgacttt ccatgacttg caggccaatg atccgacact caaccggaag
     7321 gaggaatttc agaaatatct ccgtatggga ggattcccag ccatacatac tgccgattat
     7381 ggatatgagg ctatctataa aattgtctac gacatctatt cttctgtcat tcttcgtgac
     7441 acggtgcagc gtcacaatat ccggaatgtg gagctgctcg aacgggtagt gaagtttgtt
     7501 ttcgataata taggcaataa gctgaacgct aaaaatatag ccgattactt caaaagtcag
     7561 caacggaagg tggatatgaa taccatctat aattatctga atgcattgga aagtgctttt
     7621 atcattcaac gtattccccg gtatgatatt aaaggaaagg aaattctgca gacgaatgaa
     7681 aagtattttg taagtgacct ttctttgatt tattccgtga tgggctatcg tgaccggttg
     7741 attgcaggta tgttggagaa tctggtctgt ctggagttga aaagaagggg ttatgaagtg
     7801 tatgtaggca aacaggatga taaagaagtg gattttgtag ccatccgtcg ggaagaaaag
     7861 atttatgtgc aagtaacgta tcagttagct tcacaggcca ctgttgagag ggagtttgct
     7921 cctttgctcg ccattaacga ccattatcct aaatatgtag ttagcatgga caacttgtgg
     7981 caggataatg tggaaggtgt caggcatcgt catatagccg atttcttgtt ggatgatgct
     8041 tgacgctaag gaatatagaa aacgaaaaag aggaaattct ctgcgagaat ctcctctttt
     8101 ttcatctttc acgaaagatc gaattatttc ttcttacggt caccgtaacg gctcatgaac
     8161 ttgtcaacac gacctgcagt atctaccaat gtagatttac ctgtatagaa cgggtgagaa
     8221 gtgtttgaga tttcaatctt cagcaacgga taagtttcac cttcgaattc gatggtttct
     8281 ttagttgcta cagttgatct agacaaaaac atgtcaccat ttgacatatc tttaaatact
     8341 accggacggt atgattttgg atgaaggcct tttttcattt cagtatctgt ttttttaatt
     8401 tatattctgt tactattttg gtaagaaata gtgtaatggt cattttcaga gcgcaaagat
     8461 aatgcttttc tgtgaaatag aaaaaggttt tctaaaattt ctgatttcta atttatgatt
     8521 tctgatttgc tatgcagatt ttgatgatta aatgaatgaa aaatgaggta taaataaggt
     8581 ataaataagg agatataaat ccgaaggcat caatcagaat tcagaaatca taaatcccaa
     8641 agtttgcaag gtggacatta caatctaatg tcacactcgt attcctgcta aattttgcag
     8701 tctgatttaa acctttttct actatatttt tctttccgat gttcgttatt cgatggataa
     8761 tgcttacttt tgcgtagaat ttttattcac taacaataaa ctttaaacaa aatggtaaat
     8821 tacaaagatt taggattggt aaacacaaga gaaatgtttg ctaaggctat caaaggtgga
     8881 tatgctatcc cagcattcaa cttcaacaat atggaacaaa tgcaggctat catcaaggct
     8941 gctgttgaaa ctaaatctcc tgtgattctt caggtttcta aaggtgctcg tcagtatgct
     9001 aacgctactt tgttgcgtta catggcacag ggtgctgtag aatatgctaa agaattaggc
     9061 tgcgcacatc cggaaatcgt tcttcacctt gaccacggag atacattcga aacttgcaaa
     9121 tcttgtatcg attctggttt ctcttcagta atgatcgatg gttctcacct tccttacgaa
     9181 gaaaacgtag cattgactaa gaaagttgtt gaatacgctc accagtttga cgtaactgta
     9241 gaaggtgaac ttggcgtatt ggctggtgta gaagatgaag tttcttccga ccatcacaca
     9301 tatactgacc ctgaagaagt aatcgacttc gctactcgca ctggttgcga ctctttggct
     9361 atctcaatcg gtacttctca cggtgcttac aaatttactc cggaacaatg ccacatcgac
     9421 ccgaagactg gccgtatggt tcctcctcca ttggctttcg aagtattgga cgctgtaatg
     9481 gaaaaacttc cgggattccc tatcgttctt cacggatcat cttcagttcc ggaagaagaa
     9541 gtggaaacta tcaacaaata tggtggtgca ctgaaagctg ctatcggcat tccggaagaa
     9601 gaattgcgta aagctgctaa gtctgctgtt tgcaaaatca acatcgactc tgactctcgt
     9661 ctggctatga ctgctgctgt acgtaaggta ttcgctgaaa aaccggctga attcgaccca
     9721 cgtaagtatc ttggcccggc tcgtgacaat atggaaaaac tgtacaagca caaaatcatc
     9781 aacgtgctcg gttctgacaa caaattggca cagtaataat ctccggatta ttccataaat
     9841 aaaagaaaga ggctgctccg gtttgaacac tggtagcagc cttttttatg acgtttaatc
     9901 gtttcagaac ggagagaaga taacactatg gctgtaataa agaacacccg tgtcacaact
     9961 gaatgtaaca cgggtgttct tatctattat ataatgtttc ttacatcaag aatccaagca
    10021 gaataccggc agcaacagct gaaccgatca ctccggcaac gttcggaccc atagcgtgca
    10081 tcagcaaata gttggtcgaa tcatattcca aaccaatcac ttgcgagata cgtgcagagt
    10141 cgggaacagc agaaacacct gcattaccga tcaacggatt gatcttatta cccttcttca
    10201 ggaagatatt gaagatctta acgaagatga caccggatgc cgttgcaata acaaatgaca
    10261 atgcaccgag ggcaaagatc ttgatagagt caagcgtcag gaattcggat gcttgtgtag
    10321 aagcacctac tgtcagaccc aacaggatag tgattgtatc aatcaacgga ccactggcag
    10381 tattagccaa acggcgggtt acaccacttt ctttcaacag gttaccgaag aacagcatac
    10441 ccagcaaagg cagaccggaa ggaaccagga aacaagtcag caacaaaccg atgatcggga
    10501 aaatcacctt ctccgtgtga gaaacggcac gcggcggttt catgcggatg acacgttcgt
    10561 tcttggtggt gagcagacgc atgataggcg gctgtatcac cggaaccaac gccatatagg
    10621 agtaggcgga caccgcaatg gctcccatca ggttaggtgc tagcttggaa gaaaggaaga
    10681 tggccgtcgg gccgtctgct ccaccaatga taccgatagc accggcttgc atcgggtcga
    10741 agcccatttc taacgcgatc atataagcac cgaagatacc gaattgtgca gctgcaccga
    10801 tcagcatcaa ttttggatta gagataagtg ccgagaagtc cgtcatggca ccgatgccca
    10861 aaaagatgag cggcggatac cagccggagg tcactccctg atacaatata ttcaatacag
    10921 aaccttcttc ataaataccg actttcagcc cggcatccat attaaaaggt atattaccga
    10981 tcaatatacc gaaaccgata ggaatcagca gcatcggttc gaactctttg gctattgcca
    11041 aatagatgaa taccaagcca acgagaatca tgactacatg ccctaccgta gcattggcaa
    11101 agcctgtgta tgtccagaag tcggccaggt tatttcctaa aaagtttata aagtctccca
    11161 tattattcaa taattacgag gtcattacct tcaagaacag agtctccctt gttgacgttg
    11221 atggcagtaa tcttaccgtc cttatccgca ttgatattgt tttccatctt catggcttcc
    11281 aatatgataa tggtctgtcc tttctttaca gtatcgccta cattcacttt gatgtcgagg
    11341 atcacacccg gcagcggaga ttttactcct gattttccgg tagacggagc ggtcggtttc
    11401 actacttgag taggagcagc aggagcatta ggcatcgggc gtactgtcac gggtttcgca
    11461 acaggcttcg gctgtttctc catttctact ttatagtgtg taccgttcac ttctacatga
    11521 gcgatgttgt cttcaatatc tccgatggtt actttatatg agttaccgtt gattttatat
    11581 ttatattctt tcatcgtttt tactttttaa aaggtgactt actttctggg aggagtttca
    11641 cgcaaagtgt aaatcttcga actccatggt gagtagctgc gttttacgcg ggtgatggtc
    11701 agcaccgttt cttctacgtc gtgcacctca tcctgcattt cgtgtaatgc catagaaata
    11761 gcagcgtata cttcgcccgg agcctgtgac agttccttag cttcatgctt gtcaatgcct
    11821 ttagatttca tagcgttgcg cttgctcaaa ttaacagcta cttttcctac aatcttaaaa
    11881 gcaataaaga gaagaatcaa tccgcagaat actacgctca tggcagaaat ggacattcca
    11941 acgccatcag catcgtgttc ttcaaacttt tccatcttgg aattgctgtc aagagtcttg
    12001 ttgttggtgc tcggagtcac gtatttgtca ccgcttccac tttttacttc ccattcagct
    12061 gccccgtcgc ttacacgagc gtatgattgg ttgggaccga gcgcgcctgc aggcactaca
    12121 atctggtcga gcaacttctt gccggagtcg aacagaccta cccagttagc tgtttccgga
    12181 ttcagcttga agctggtatg gaaagtacca cggttaggtt cgccatctgc ccagaatagt
    12241 gcatgttggc gtggtttcac taaggtaagt atatcacctt tcgggataaa ataagtaact
    12301 gtatcgcccg gttggctgct tactttcagc aagcaagctg ccaggtcggc gctaccgaat
    12361 gatttattga atatttcaat ccatgcgctg tgcaatccgt aatcgtcctg aaaattactc
    12421 tgattgtcta tcaggatttc gtttagcacc agcttattgt tcgacttttg ctctccacaa
    12481 gaagtcagac caatcagcaa cagcaaagaa aggaatattc cgattttggt tttgttcata
    12541 atcgttcttg ttttaatgtg aaaagtagga ttacaacgga atattaccat gcttcttagc
    12601 cggattgctc aatttcttag tctgcaactg ctgcaaagca cggatcacac ggaaacgtgt
    12661 gttgcgcggt tcaatcacat cgtcgatgta gccatattta gctgcattgt aaggattggc
    12721 gaacaatttc gtgtattctg cttctttctc tgcaaggaat tgagcagggt tttcctgatc
    12781 tttggcttcg cgtgcgtaca atacttctac tgctcctgca ccacccatta ctgcaatttc
    12841 ggcagtaggc catgcatagt tcatgtcacc gcgaagttgc ttacagctca ttacgatgtg
    12901 agaaccaccg taagatttac gcaatgtgat agtaacctta ggcacagtag cttcaccgta
    12961 agcatacaac agtttagcac catgaaggat aacgccattg tattcctgac ctgttcccgg
    13021 aaggaatccc ggtacgtcta ccaacgatac gataggaata ttgaatgcat cgcagaaacg
    13081 aacgaaacgt gcacccttac gagatgcgtt gctatcgagc acaccagcca gatacttagg
    13141 ctgattagca acgataccta ccgattgtcc gttgaaacgg gcgaaaccga tgatgatatt
    13201 ctttgcataa tctttctgga tttcaaggaa ttcaccgttg tccacaatag cgccgatcac
    13261 ttcgtacatg tcatacggtt tagtagggct gtcggggata atatcgttca aagaatcttc
    13321 cagacggtcg attgggtctg tgcaatctac ataaggagct tcttcaaggt tgttttgagg
    13381 aatatagctc aacagtttgc gaatcagttc gaaaccttct tcttctgttt gggcggtgaa
    13441 atgagtcaca cccgatttag tggagtgaac gcttgcgcca ccgaggtttt cctggctaac
    13501 gtcttcacct gtaacggtct tcaccacttt cggtccggtg aggaacatat aagaagtgcc
    13561 ttccatcatc agtgtaaagt cggtcagagc cggagaataa acagcaccac cggcacaagg
    13621 accgaagata ccggaaatct gcggaataac acctgaagca aggatgttgc gttggaagat
    13681 ttctgcataa cctgccaaag cgttgatacc ttcctggata cgtgcaccac ccgagtcgtt
    13741 gataccgata caaggagcac ccatcttcat ggcctgatcc ataattttac aaatcttcaa
    13801 tgacatcgtt tctgacagtg aaccggcaga aacagtgaag tcctgtgcga acacatatac
    13861 cagacgtcct tcgattgtac cgcagccggt tactacaccg tctcccggat aatgtttttt
    13921 ctccattccg aagttcgtgc atctgtgctc aacgaacatg tccatttctt cgaagctacc
    13981 ctcgtcaagc agcatagcca aacgctcgcg tgctgtgtat ttcccttttt catgttgctt
    14041 cgcaattgct ttttcgccgc ctccgatacg tgctacggca cggcgttcaa taagctcttt
    14101 aattttttca agttgattac tcatgagttc ttgttggttt tagagtttat gattaatgtt
    14161 cgcagagttc tgtcaacacg cccaaagttg atttcgggtg aaggaaagca atattcaaac
    14221 cttcggcacc tttgcgggga gctttgtcga taaggcggat ttctttgctt tctgcttctg
    14281 ccaaagcatt ggctacgcca tcttctacag caaaggcaac gtgatgaaca cctgcacctt
    14341 tgttttcaat gaatttggca atagtactct ccgggcaagt cggctccaac agttcaattt
    14401 tggtttcgcc tacttttaaa aaagcagttc ttactttctg atcttccact gtttcaatgt
    14461 tgtaacactt cagacctaat acattttcgt agtaaggaag ggcttcttcg atgcttttta
    14521 cagcaatgcc cagatgttca atgtgtgaaa tcttcataac tatacttttt ttatttggtt
    14581 ttaatcatgt gcttatatgg cataaaacag cacaaagaaa gacatttctt acctaataaa
    14641 gaaatatttc tgcatttaat tattggatta ttaaacagaa aaaatggtag ggaaggagca
    14701 tgaagagtcg ttttgcaatc ttgagattac atttagacat aaaatttgac taagagtttg
    14761 ttcagccaat tccaattgac acggaaccag cggcgggtac tgctttgctt tcctccgaat
    14821 cggagaacga aatcacgata accgtgtttg cggaacggaa gtcctacatc cataaattcc
    14881 atgtgacgga atccccgttg gcgggcgtct tccaatgcct tccaaacggc cagcactccc
    14941 ggatactgaa gtgcgtatgt ctttttcatt cccccggaga accaaaggta ggcgtcatct
    15001 cccgagtaga tacagacgga accgccaatg attttctctt tgtattttac tacgaatatt
    15061 tttgcctgct gtcctttgat tagcatatcg ttcatgtgac ggaaaaagtc gttggcaggg
    15121 aaatatctgc gtatgcggga ggaataaacc ttgtgcagca tccgtgagaa atcgtgtatt
    15181 tcttccacgg tatgtgcttc ctctactttg gctccattct tgagtccttt ttttatctga
    15241 cggatgcgtg acgggctgaa ccggtcttcc gtctttttca tactgtgcag cgaattgcgt
    15301 acccgcagcc aattgacagg gaaataatca ttggcacgga aaacccggta accgaacatc
    15361 gaattattga ggttccggaa ttcgatcagg acacagctac gcgatgcttc ttgtgtgaga
    15421 tgttcgagca tatcgccaaa gacttcttct gccttttctt tgttggtcga aagcgactca
    15481 tccagaaatt caccttcgct atatactacg caatgtttca ctaaagagga gggaagccac
    15541 tttttcgctt tgcggatggc agcaagcagg cgtgccacag gtctgccgtc ttctgttgcc
    15601 actattaata aaggagtata ccccggagtc gcttcataaa tttgaaataa ctctttggaa
    15661 tggaaggcgt tttttcccgg caattcagga atgtccttcc catgataata tgtggttagt
    15721 ttaagtggca tctaggtaca aatttacact ttttattctt tattcaacaa caaaacaaag
    15781 attttgttgg aactgcctga agtaaagtac aatatatctt tgcatattta atggaaaaaa
    15841 tgtattttat aggagaaata tggtatgaaa agtgagtacg tattaaaatt atgttcgtct
    15901 taaattaaga ttataatcga atagtttttg caaaacaacg agaattaata ttaactttaa
    15961 attagaacga atgagatgta atgcatttgt tgaagcatgg aagaattatc atagacgcgc
    16021 ttccatgatt ttagggttgt ctttattggc tgcccctctg tcatacgctg tttatgcaga
    16081 agatggagtt tctaatacta tggtgcaagt tgtcacacaa acgaaaactg tgaaaggaac
    16141 tatcattgat gaaagcgggg agccgctgat tggagtttct atcgttgtga aaggaacaag
    16201 tacaggtacg attaccgatt ttaacggtaa cttctctatc gatcttccgg cgggaagaaa
    16261 agaactggtc atttcttata tcggttacaa agaacaaacg gtgacagtga caggcaacgg
    16321 accggtcaat gtgaaaatgg tttcggacac acaggcattg gatgaagtgg ttgttgtggg
    16381 ttacggtacg atgaaaaaac gcgatttgac aggagctatc acttctgtaa aaagtgaaga
    16441 tgtagtgatg aatccaagtt caaatccgat gcaggcttta caaggtaagg tggcaggatt
    16501 ggatattacg cgtgaatcgg gacaggccgg ttcgggagta aagatgcagt tgcgtggtaa
    16561 ccggtcattc cagaaggatt ccggaaatcc tttatttata attgatggta tgccggggga
    16621 ttattctaca ttgaatccga atgatattga aagcattgaa gttttaaaag atgcttcttc
    16681 gacagctatt tatggttcaa gtggtgcgaa cggtgttatt ttaattacta ctaaaggtgg
    16741 taaggaaggc aaagcaattg ttaattttaa tgcatacgta ggtgtaaacg gctggtcaag
    16801 gactccggag atgcgtagtg gagaaagtta tatacaaacc ttgagagatg catctgttgg
    16861 tgctggcgat ggacgttgga gttcggttgc tgatgataaa aatctgttta ctactgatgc
    16921 tgaatggagt gcacatcaaa atggccaata tatagattgg gtggatgctt tgttgaaaac
    16981 cagtgtaaca cagaattatt ctgtttctgt ggctggtgga acggaaaaga caaaggcata
    17041 ttttttctct gaacttctct aatgaggatg ggcagtttgc acaagatagc tataaacttt
    17101 attcatctaa aatccgggta gatcataaga ttaaaaagtg gatgaaggtg ggcattgatg
    17161 ctcaactgtc ttatgtacat caaaataaag ctgattctga tttacagact ttgatggcgt
    17221 caaatcctct tggatcgttg tataatgaag atggaagcat caatccgcaa cctgttgccg
    17281 atccttcatc tacagtatat aattatcttt taaatgagga taaaagtttg taccgcaatc
    17341 aggctcaaaa ccttaaggtc tattttaatc cttacttgga aatcactcct cttaaagggc
    17401 tgacttttat tactcgtgct ggtgctagtt tgggatattc acgtagtaac actttcacag
    17461 gagaggggtc tgttcaatgg tataaggcaa atcaaacggc agacggcatt aaggcgcaag
    17521 ttaaggacaa ccgttcgtat aattataagt gggaaaatat acttacttac aatttccaga
    17581 ttaagaaagt gcatgatata actcttactg cagttacatc ttggaatcac aatcgtagcg
    17641 atgtcactac tttgtatcaa aaaggtgttt ctgataataa attcttatgg cataatattc
    17701 ttgatggtaa ttccgcaact tcgggaagta cttcttatag tatgtctaag gggatgggat
    17761 atgtcggccg tttgaactat tcatatatgg gtaggtattt atttgctgca tctgtccgcc
    17821 atgacggctc ttccagactg gcagaaggta ataaatggga tactttcccg gctttttctt
    17881 tgggatggag aatctctgat gaaaaattta tggagagtac gactaactgg ttgagtaatc
    17941 tgaaaattcg cttcggatat ggtgttacgg gtagtacagc gggtattgat ccgtattcgt
    18001 ctgctgcatc attggatgct actgctgtaa atatgatatt aggaggtgtt ctgacgccga
    18061 tttataaatt ctcacagaat attccgaact atttgcttac atgggaaaag tcgtataaca
    18121 cgaatattgg tattgacgct gcattcttaa ataatcgcat tgatgtcagt atggaatatt
    18181 ataatacaaa aacaaaagat gttatatgga acaaggcact tcctgttatt aatggagcat
    18241 tctccccgga tggcggacct aaagcgaatt atactactaa tttaaatatg tgtgagacta
    18301 gcaataaagg ttttgagttg gctcttaata cacgtaatat tataacaaag aactttatct
    18361 ggagttcaag tgtaactttc aatcataata aagagaaaat aaccaaattg tccggtggag
    18421 attcagatgt gcttaataat ggtgacaccg gttatgcatt ggcattggga gaagctatta
    18481 actcttatta tcattataag ttggatggtg tatggcaaaa aggtgaggaa actgatgcgg
    18541 cggtatttgg tgctgcacct ggtgatttga aaatcaatat acctaattta gtaaaagaat
    18601 ctgatggtag attctataaa atagatgaag aaacgggtag tgctgctgta gatgaaaatg
    18661 gtaatgttat ttattacact tctgataata aatatactcc aagtgatgca gattatcaaa
    18721 ttctgggtca caactctccg gattggtctt taggattcca gaataatttt acctggaagg
    18781 attttgattt aagtgtgttt gtttatgcac gttacggaca gatgtttgct tatgatatgt
    18841 tgacgtctta tgacccgaag ggtatacgta acttcccgac ctattttaat tattggactg
    18901 aaaacaaccc ttcaaatgat tttcctgccg ccaatgctaa taaaggtctc gaacaatata
    18961 cgggatatta cgcattacgc tatgtagacg gttcgtttat aaagattaag aacattacat
    19021 tgggatatag tctgccgaaa tctatcttaa aatcagccgg tatagagaag tgtcgtttct
    19081 atgctaccat tacaaatccg tttgtatttg cgaaaagcca tttgctgaaa gactatgatc
    19141 ccgaaatgaa tggttctctg aagtacccat tgaccaaaca atttgtattt ggtgtaaatg
    19201 ttacattcta gtttttcact aaaaaagtat tgaaatgaaa agtacaatct ataaaatagc
    19261 agcgcttaca ttcgctgtgg cttcaatgtc tgcctgctcg cttgatgagt ataatccaag
    19321 ccaaaaaaca ggagatgaaa ttcttgcaac gttcgatggg cttaaaggat tacagtctta
    19381 ttgttattca tcactttacg ggcagttatt cagtgtctat gatttcttgt ctgtggctga
    19441 aggtggtacg gactgctgga ttactcctgc cggtaatccg gattatgcca agcaggtgat
    19501 ttattatgat ggtttagcta cgaatacgaa tgctacaaat aaattattcg gtcaggctta
    19561 ttctatgatc ggtaattgta atgcagtagt aaacagggct gaattactaa cggatggcaa
    19621 tgaaaaagat ataacgactt tagtggctga agcccgctgt cttcgtgcgt tttattattc
    19681 catattggtg aatacgtatg gaaatgtaac gttaacattg gaagaatcgt ctcaagatcc
    19741 tattttgact ccgcagcgta actctattga agaactatat acgcagataa ttgatgattt
    19801 gaaatttgcg gccaataatc ttgaagatac tccttatgat aataatcgtg cgcgtgtgac
    19861 taagaaaacc gcgttaggac ttttggctcg cgtttatgct caaggtggtg gcgaatatgg
    19921 gctgacagaa gagggagtat cttattggca acgtgctaaa gaagtggcag aggacatgat
    19981 tttagcgtat ggtgactgtc tgtatgatga tgtggaagat gtttgggctc cggcaaataa
    20041 tcgaaataat aaagaagctt tatttattgc tgccggtccg gatgctacga atttggagaa
    20101 ctggaatgct ggaacacaat gtaataacaa ctttacttat atgtatccaa agccaaatac
    20161 tctcactatt tatcctactc cggataatca aaattattgg tatggacgta ctaataataa
    20221 tacgttggca ccttccaaat atttgctgga ttgttttgat gctgattatg ataagcggtg
    20281 ggaagtaacc tttactacgg cttttgtaca gttttctgcc gtacagtcag gaggtagtta
    20341 tttatttact aataagaagc agacattgga tgatggtaca aaaccaaaaa ttggaacaaa
    20401 acatggcgta aatgataata ttagttcatt tacaattctt actcaaaata taatcgatac
    20461 ttatggattg gatgcaaaat tccataatga gtatatttat ccttatggtg atttgaatta
    20521 tacatattat gatggaactt gggcgcccaa aatgatagcc aaggtttggc cgaaaggtga
    20581 aaatagcggt gatccttcca aattgcagga agtgaagaac ccctatgtga taccttaccc
    20641 tgtagctgaa gatgatgata gaatctgttt ctacttatca aaggaaagac tttcggatgc
    20701 ggagaaagcg aaacgtagat attatgtaat caatattgat gatttgtttg ataacggaca
    20761 atatcgtaaa acagatataa aagttactaa tgacaaaaat atgtaccctg gtttcaacaa
    20821 atacaattgg ttgtcggaag attcatatag tagcaatttg caacgtaaga caggtgatgt
    20881 gttcattatg cgtatggctg aagtatatct gattgcagct gaagctaacc aacaattagg
    20941 aaatggcgga aaagctgctg aatatttaaa tgtactgaaa aagcgtgccg ctcgcaatga
    21001 tgcatcttac aatgctatga aattgagtaa tgctacacag aatgatgtta tggacgaata
    21061 tgctcgtgaa ttatgtggag aatatcaacg ttgggtattg atgaagcgtc acaaagattc
    21121 ttttaaacaa cgtcttgctg ttggtaatcc tcgtgcagct gaaaattttg atgaaaacaa
    21181 gcattatttg cgtccgattt cttttaactt cttgagtcag attgataatg cagaagaata
    21241 tggaaacaat gggtattagt actcttacag attaaattta gattaaagag gggatatgtc
    21301 gtgatgatat gtcccttttt tctatatctt tgcgtaatcg aacagaactt ttaaaaagcg
    21361 gaactatgtt agaagaaatt ttagcttaca acaagcaatt tgttgagaac aagggatacg
    21421 aatcgtatat taccaataaa tatcccgata agaaaatagc tattctttcc tgtatggaca
    21481 cccgactgac tgctttgctt ccagccgcat taggaattaa gaatggcgat gtgaaaatga
    21541 taaaaaatgc aggtggtgtt atttcccatc ctttcggtag cgtgatacgt agtttacttg
    21601 tagctatttt tgagttgggg gtagaggaaa taatggtgat tgctcattct gactgtggag
    21661 cttgccacat gcacagtgaa gtaatgctcg aaaaaatgaa agcacgcggg atcaatccgg
    21721 attatattga catgatgcgt ttctgcggag ttgactttca ttcgtggctg gatggtttcg
    21781 aagatacaga aaagtcggtg agaggaacag tagattttat cgtgcgtcat cctttgatcc
    21841 cttcagatgt gacagtctac gggtttatta ttgattctac aaccggggaa ttaactcgga
    21901 ttgtatagat aattagatag attaggtaaa tagataaact tcttttttaa tcccctaaat
    21961 atagtgacgc tatcctatca tgatagtgac gccattccta ttgtatagtg tcgctatgtc
    22021 tggaggatag ggatattcct aaaataataa aatttaaggc aactaattca ttgcgagtta
    22081 gttgcctttt ttgtatcttt aagcattccc cccaaaaaac ggtttgacgg ccaaaacggg
    22141 ggtaattaaa aataaaaaca catggtaaag atacaaaaaa tctcagaaat cgaaccttgt
    22201 ttaggtttta ccgagttcga tatgcttaaa aaatatcgtc aaagttttgc aacgagtgaa
    22261 ttaggtcgcc tccattctct gttccctttc tcggaactgg cccgacaaat gcatttgaag
    22321 tcctctcctt ttgggcgtaa aagttatttt tctcccgaag gtaaaatagc cttgatggtc
    22381 ttgaagtcct ataccaactt ttccgatgca caactgattg agcatttaaa cggtaatatt
    22441 cattaccagt tattttgtgg tgttcagatt gatccgcttc atccactaac caatcctaaa
    22501 atcgttagtg caattcgtca ggaactagcg gatcgccttg acgttgagtc cctccagctc
    22561 attcttgccg agcattggac accttatctt gagaaccttc atgtctgtat gaccgatgcc
    22621 acctgttatg aaagtcatct gcgtttccct actgatacca aactcttatg ggaaggtatt
    22681 gtatggcttc atcgtcatct gtgcaaacat tgccagacct tgcacataca acgtccccgt
    22741 aacaagtatc ttgatgtacg ccgtgcctat cttgcttata gcaaactgcg taaacgcaag
    22801 aaatcacaga ctcgtatgat tacacgaagg ttacttcagt tattggaaaa gttacttgac
    22861 cagctggagc tgcttcattc atcctacagg aacaggctta cactatcctc tgattaccaa
    22921 agacgtttct cggtcataca gacagtcctt gagcaaggga agaatttatt tgcaggcaaa
    22981 aaagtgtcca accgtatcgt gagtatcgac cggcattacc ttcgccccat tatcagaggc
    23041 aaggaaacca aatccgttga attcggagcc aaagtcaaca atatacagat agacggaatc
    23101 tcctttatag aacatatctc ctttaaggct tttaacgaag gagtacgttt gaaagactgt
    23161 attcatctgc aacaacaact gaccggggtt agggttaagg cgcttgcggc ggattcaatc
    23221 tatgccaata atgccaaccg gaaattttgt acaaaatatc atataagtac ttcctttaag
    23281 cgtaagggca gagctgccaa agatgagccg cttcggaaaa tcttacggtc ggaactcagc
    23341 cgtgaaagag ctacccgcct ggaaggaagt tttggaacgc agaaacaaca ttactcactg
    23401 gccaggataa aagctagaaa caggaaaacg gaagtacttt ggattttctt tgggatacat
    23461 acagccaatg cggtatgtat gatagaaaag gtcgaaaaaa aaaaagaaag gcagcataat
    23521 ctaactaaaa taacaggaaa aacaggagag gttttaactt cccctaaaaa agacatgtac
    23581 ataatgcatg ggtgggaagg aaaaaataag aatatgtaaa caatattcta caaaaaagat
    23641 agaagactgg gagagttgaa cgaaaaaatc aagagaaaag ctcacgtaaa gcaaagcttt
    23701 tctcttgatt ttttagaaag aggaacattt actgaatatc ccaggatagt gacgctattt
    23761 tgaagacaaa aaaataaggc agctttttgt cggctgcctt tatctttctg cggttatata
    23821 ctttctttga ctggtgcact cgtttgtgac aaatagggtg tccgtacatc tcaatttctg
    23881 cctcacggct agctttacga ttcgctttaa cgtaatcgtc ctgtgtaatt cgctttttca
    23941 taatgaaatt atttctctgt gcaaagatac aatatattct tcatttagta taaactttta
    24001 tttcctatta cgctcggttt gcattatctt tgcatacatt aatcaaatga aaccggaaat
    24061 aatatggaaa atttcagtga attgataaag aaccgtcgta gtatgcggaa gttcaccgat
    24121 gaagaattga cacaaaatca ggtagttgcg ttgatgaaag cagctttgat atccccttct
    24181 tccaaacgta gtaatagttg gcagtttgta gtggttgatg ataaagaggt attgaaagaa
    24241 ttgtctcatt gcaaagaaca ggcttcttcg ttcattgccg atgcagcttt ggcgattgtt
    24301 gtaatggccg atccgttggc cagcgatgtt tggattgaag acgcttccat tgcttccatc
    24361 atgatacagt tgcaggctga agatcttggc ttgggaagtt gttgggtgca ggttcgcgaa
    24421 cgtttcactg ccaccggaat gccttccgat gaatttgtcc atggaatttt ggatattccc
    24481 ttgcaacttc agattctttc tgtcattgct atcggacata aagggatgga acgtaaacct
    24541 ttcaatgaag aacatct
//
