LOCUS       gnlProkkaEILOEECH_1    22756 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EILOEECH_1.
ACCESSION   gnlProkkaEILOEECH_1
VERSION     gnlProkkaEILOEECH_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 09:23:59
            Original ID  :: gnl|Prokka|EILOEECH_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 3156843
            Orig. end    :: 3179599
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..22756
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[10000:12756]"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12756
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="10000"
                     /detection_rule="(HMGL-like and AMP-binding)"
                     /neighbourhood="10000"
                     /product="betalactone"
                     /protocluster_number="1"
     cand_cluster    1..22756
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(HMGL-like and AMP-binding)"
                     /kind="single"
                     /product="betalactone"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..22756
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="betalactone"
                     /region_number="2"
                     /rules="(HMGL-like and AMP-binding)"
                     /tool="antismash"
     CDS             414..1250
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     136.6; E-value: 1.6e-41)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2979"
                     /transl_table=11
                     /translation="MNTAIVKRAFRYIFRGIPRPHISIAVKNFTTRRLEGRKILITGGG
                     KGIGYWIAKKCVSEGAKVLICGRQEETLRRACRELGESCQYIKFDVSSIIDIPSFLNEA
                     FLRMNGIDSLVSNAGISLHEGSFKNVTESGFDAQFKVNFKAPYFLAKYFVEKIENEKIG
                     SANILFVTSERGSFCTSIPYGLTKSSLKSYVGALCRYYCFNERIRVNAIAPGVTSSEMT
                     GYSENGDFQTDDSPNGRIFHPAEMANVACFLLSDEASCISGETIHCDFGRHQSVID"
     CDS             1285..1686
                     /locus_tag="ctg1_2980"
                     /transl_table=11
                     /translation="MIDSIISCLNAKGVVRFVNTTTQIKEKISYPSNIEWYYIEDVRSA
                     VFNAYGMSKISHSPVAIIVEEAYLPNTYTALTEAWLQRVQVIVLALNSMNLDSSFYLNR
                     CVDASILIDNVETIEGVVCNAIQHHNLLL"
     CDS             2120..3853
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TPP_enzyme_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 61.1;
                     E-value: 1.4e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2981"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1e-21, bitscore:
                     75.4, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKTKIKQVQQIVSLLKQNNIRHFVLSPGTRHVAFVHIVEMDPFFR
                     CYSIVDERSAAFFALGLSEALDEPVGFACTSATASCNYMPAMKEAYERNIQLVALTSDK
                     QRYQRFHGVSQVINQVDMFAPYCRYAVDLPEVNDSMDEWFCNRCINEALLEMDHHGRGP
                     IQINFLEPSSIDELSIFYDGNMPVCRKINRIEDWSQINEWKNVLAAKKRILVVCGQYQE
                     FTGCLRSSIRKFYEKYNCAVSFDAFSNVADKDFIQTMLLSITLNQKELLSLKPDLIITF
                     GTKYFSDIVSRFAGMGIEHWEINFEGRIFDTSRSLTKIFEFTPEEFFDKVSYNITTNDK
                     QYDKLWRALNESRDNSIDEFTNYYVAKKVLESLPEGSNVHASVLNSMKFTNMSKLPQNT
                     IATGNNCADGIDGALSTFIGQAEVLDSLSLLVIGDLSYLYDLNAAIHDFKNNTRVLLIN
                     NFAGGEFHFNIGKKKISTLEQHIAAGHHTKIQDAIGLSNFQYIAVHNKGELEEKLSLFL
                     RESENPILMEVFTNPELDGSSLKKLIRNNIKMTPERLIAGFVNKFLDCRTKYAIKKFLH
                     R"
     CDS             3886..4989
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Glycos_transf_1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1045:glycosyl transferase group 1 (Score: 95.5;
                     E-value: 6.7e-29)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2982"
                     /sec_met_domain="Glycos_transf_1 (E-value: 1.3e-24,
                     bitscore: 84.8, seeds: 63, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRVLIYGFTGNVLGGIEVYTLNMSEYMSDDCVFDYIVDGDECAYR
                     ERITKRGGKIFFVPWVRRHPLGYINKLWRIFGEEKKSGTNILYHQLFTMSNLIPDVIAK
                     LRGYKVILHAHNNGLQKGGRMYLMAHNLGKILSRFCGFVMFTNSQLSSDYMFGKGVNSK
                     LIYNAIDVGKFAFKQEHRDCIRKELDCQSKTVIGFVGRLVDQKNPLFMLKVFAEIHKLR
                     PNSELWIIGEGILRGKMEVEINEQGICSSVKWLGRREDVNRLMQGMDLLLQPSVFEGLG
                     IVLVEAQATGLAVVSSEVVIPKEAVISDRIKLLPLSEKSAYWAAESVNLLDSCCESYDR
                     TNAIVPDCYNIQHEAKRLESMLKELIS"
     CDS             4994..6163
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Wzy_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2983"
                     /sec_met_domain="Wzy_C (E-value: 4.3e-06, bitscore: 24.9,
                     seeds: 81, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIPVKTSKWFTYYLLFLPLVMMYSVPGTGIRIPTLLTAIAMLYS
                     LLQLANRHMRVPIYMLLPLFMYLTYVMFKSSLQLAFLCGSVIIIISAICTGIVNVFLLR
                     KVLEKVAIVAAFCVIFQQIVHILTGIHFHFYLLPFFANDLLEQYNNAITTGAVEGMYRP
                     CAFFLEPAQYSQYCTIGLGSCLFTHRPKTKNALFISLGIFASTSGMGFVSVFAIWGAWA
                     LSRQKTKKNFIRSLPVILIALFLVFFLLDNISFTHNIINRFTSTSGDDYNAINGRLFWW
                     DTYFGDFNVSDFLTGFGLDNLPDGVYFTGFMKLLYCYGLIGTTLLLLFLGMLIIKADIF
                     VKVCTSLYTGLLFFADLTYYHNLIFYIGVYLALYIFNKERVNIAGTLKA"
     CDS             6649..7257
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Bac_transf"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1146:sugar transferase (Score: 240; E-value: 8.8e-73)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2984"
                     /sec_met_domain="Bac_transf (E-value: 6.6e-62, bitscore:
                     206.2, seeds: 461, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYKHFFKRPFDFIISLVALICLSPILLAVTIWLHFANKGAGAFFI
                     QARPGKDAEIFKVIKFKTMKDEFDEKGEPLPDEVRLTKVGKIVRSTSLDELPQLLNVLK
                     GDMALIGPRPLMPEYLELYTPEQMRRHEVRPGITGWAQIHGRNELPFTERFEYDVYYVD
                     HLTFGLDLKIFFMTIVKIFKREGISQKGQATVETFDGTN"
     CDS             7272..7559
                     /locus_tag="ctg1_2985"
                     /transl_table=11
                     /translation="MKHLVIIGGGGMGKDIYHSAKHSIGYGTEYDIKGFIDDNLNSLDG
                     CEGYPPVLDTIKNYQPSEDDVFTCSIGNVKTKRTLCEMIKDRGEVHYLAT"
     CDS             7933..8172
                     /NRPS_PKS="Domain: PP-binding (9-73). E-value: 1.9e-08.
                     Score: 26.7. Matches aSDomain:
                     nrpspksdomains_ctg1_2986_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2986"
                     /sec_met_domain="PP-binding (E-value: 1.5e-06, bitscore:
                     26.7, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIMELNEFIENFAEQFDDTDASEIKADTVFKELDEWSSLVALSV
                     IAMVDEEYDITIKGDEIWNSNTVEDLFNAIKAKA"
     aSDomain        7960..8151
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2986_PP-binding.1"
                     /evalue="1.90E-08"
                     /label="ctg1_2986_PP-binding.1"
                     /locus_tag="ctg1_2986"
                     /protein_end="73"
                     /protein_start="9"
                     /score="26.7"
                     /tool="antismash"
                     /translation="IENFAEQFDDTDASEIKADTVFKELDEWSSLVALSVIAMVDEEYD
                     ITIKGDEIWNSNTVEDLFN"
     CDS             8178..8924
                     /NRPS_PKS="Domain: PKS_KR (10-168). E-value: 1.3e-10.
                     Score: 33.3. Matches aSDomain:
                     nrpspksdomains_ctg1_2987_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     177.9; E-value: 4.1e-54)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2987"
                     /transl_table=11
                     /translation="MYNPYSLTGKTILVTGASSGIGRATAIECAKLGAKVVITARNEDR
                     LKETLDTLEGEGHQMICFDLSETEKLNDFVASLPPVQGFVSNAGTTIIAPIKFIKEDSL
                     EGLLQVNTVSPILLLQRLLKKRILGKGSSVVFTSSMAALGKGTPGNTMYSASKGAISAF
                     IQNAALELSAQRIRVNAVCPGTVDTPLIHSGGITDEQLSEDAKKYPLGYGQPEDIALGI
                     AYLLSDAAKWVTGTNVIIDGGLSVSC"
     CDS_motif       8208..8300
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_2987_0001"
                     /evalue="9.80E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg1_2987"
                     /protein_end="41"
                     /protein_start="10"
                     /score="15.0"
                     /tool="antismash"
                     /translation="TILVTGASSGIGRATAIECAKLGAKVVITAR"
     aSDomain        8208..8681
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2987_PKS_KR.1"
                     /evalue="1.30E-10"
                     /label="ctg1_2987_PKS_KR.1"
                     /locus_tag="ctg1_2987"
                     /protein_end="168"
                     /protein_start="10"
                     /score="33.3"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="TILVTGASSGIGRATAIECAKLGAKVVITARNEDRLKETLDTLEG
                     EGHQMICFDLSETEKLNDFVASLPPVQGFVSNAGTTIIAPIKFIKEDSLEGLLQVNTVS
                     PILLLQRLLKKRILGKGSSVVFTSSMAALGKGTPGNTMYSASKGAISAFIQNAA"
     CDS             8941..9999
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) fabH"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1084:3-oxoacyl-(acyl carrier protein) synthase III
                     (Score: 204.7; E-value: 3.1e-62)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2988"
                     /sec_met_domain="fabH (E-value: 9.8e-49, bitscore: 164.3,
                     seeds: 7, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MAKIKINNVRIKGIAACAPSKVEENSEYPYFDENEFENIIPSIGV
                     ERRHVAKEGQTCADFAQRAAEKLMEELGWEKESIDLLIFGSPSKDYIQPDTACVLQGKL
                     DLPESCMAFDMTLGCTGWTYGMTNACSLMQTGCIKRVLLLNGIQGSAESCYYDKTGYPL
                     FSDVATATALEYDPTAAPIYCELGTIGKQFDAILVPDGGRRNPVTEGSLKLVEYEKNVK
                     RNRLHTFMKGMDVFSFALKTAPKSTNAVLEFAGKEKDEIDYFFFHQANFYMVKKIIKKL
                     KIDPEKAPIVMKDFGNTGACSIPFTMVIGCAEKLRNGKHTNVGCSFGVGLSWGSLCFET
                     ENLVIPELQIYD"
     CDS             10001..11530
                     /NRPS_PKS="Domain: AMP-binding (9-408). E-value: 5.9e-79.
                     Score: 257.4. Matches aSDomain:
                     nrpspksdomains_ctg1_2989_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     311.6; E-value: 1.3e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2989"
                     /sec_met_domain="AMP-binding (E-value: 3.3e-79, bitscore:
                     264.5, seeds: 400, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRSQLADLFYKNAAEMPDKQAIWCDGKTATYQEMANRVSRYSNYL
                     VAKGVQYGDHVAIPMNNSIESVALFFSAADLGVCLVPLNPTLPLESIKVAMKSGDMKHL
                     IARKSFLNECEKKGGVDVPGITVCLDGEFEGAFPFSEVATMPTTRPACENIKGDESLIL
                     TMTSGSTGTPKPIDISQQNKIDRSLAHIRVYGLVKEDRILAATPLYHSLAERLVIMPLL
                     LGATSILLPRFTPALWLKCAAEQKPTFTIAVSAQLAQILELLKQENTESIDSFHTIVSS
                     SALLEEKVKLELIDRLQCEFHEMYGTSETSTATDICFQKARNKQKSVGLPDEAEVKILR
                     DDEDTECAVGEVGEIAVKSKLTCKGYYKLKNMMDMATTEGFFRTGDLGYMDEDGYLYFA
                     GRKKELIITGAINVYPNDVDAVVNQLTAVEECAAFSYPDERLGEVVALAVVVKEDCELT
                     ERTIKTYCAKNLADFQQPHKIFFVDMLPKNTMGKLQRNRILDHIRNVGIDK"
     aSDomain        10028..11224
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2989_AMP-binding.1"
                     /evalue="5.90E-79"
                     /label="ctg1_2989_AMP-binding.1"
                     /locus_tag="ctg1_2989"
                     /protein_end="408"
                     /protein_start="9"
                     /score="257.4"
                     /specificity="substrate consensus: X"
                     /tool="antismash"
                     /translation="YKNAAEMPDKQAIWCDGKTATYQEMANRVSRYSNYLVAKGVQYGD
                     HVAIPMNNSIESVALFFSAADLGVCLVPLNPTLPLESIKVAMKSGDMKHLIARKSFLNE
                     CEKKGGVDVPGITVCLDGEFEGAFPFSEVATMPTTRPACENIKGDESLILTMTSGSTGT
                     PKPIDISQQNKIDRSLAHIRVYGLVKEDRILAATPLYHSLAERLVIMPLLLGATSILLP
                     RFTPALWLKCAAEQKPTFTIAVSAQLAQILELLKQENTESIDSFHTIVSSSALLEEKVK
                     LELIDRLQCEFHEMYGTSETSTATDICFQKARNKQKSVGLPDEAEVKILRDDEDTECAV
                     GEVGEIAVKSKLTCKGYYKLKNMMDMATTEGFFRTGDLGYMDEDGYLYFAGRKKELIIT
                     "
     CDS_motif       10490..10534
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg1_2989_0001"
                     /evalue="8.60E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg1_2989"
                     /protein_end="178"
                     /protein_start="163"
                     /score="12.4"
                     /tool="antismash"
                     /translation="TMTSGSTGTPKPIDI"
     CDS             11546..11797
                     /NRPS_PKS="Domain: PP-binding (29-72). E-value: 7.4e-07.
                     Score: 21.5. Matches aSDomain:
                     nrpspksdomains_ctg1_2990_PP-binding.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PP-binding"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2990"
                     /sec_met_domain="PP-binding (E-value: 6e-05, bitscore:
                     21.5, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDIKEFVTEYIQREYTVPEDVDIMTLNYIEAGYIDSMAFIQFIS
                     TIEDEYDIEFEVEDIENPKLRIVGKLIDFIQAKIDEQH"
     aSDomain        11633..11761
                     /aSDomain="PP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_2990_PP-binding.1"
                     /evalue="7.40E-07"
                     /label="ctg1_2990_PP-binding.1"
                     /locus_tag="ctg1_2990"
                     /protein_end="72"
                     /protein_start="29"
                     /score="21.5"
                     /tool="antismash"
                     /translation="IEAGYIDSMAFIQFISTIEDEYDIEFEVEDIENPKLRIVGKLI"
     CDS             11836..12756
                     /gene_functions="biosynthetic (rule-based-clusters)
                     betalactone: HMGL-like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1271:2-isopropylmalate synthase (Score: 79.9; E-value:
                     3.2e-24)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_2991"
                     /sec_met_domain="HMGL-like (E-value: 3.2e-20, bitscore:
                     70.9, seeds: 15, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLSVTGGLVNDFFFTDEFVKKVYETNVAAGVDYMEFGYRADKKM
                     FDPSKFGKWKFSSDEDIFSIVGDNPTGLKLCVMADVGRCDFKNDIHKKSDSPLSLIRVA
                     TYIETFSEAIEMIEFAAKQGYEVTCNLMAISKCTMMQLSKALDALAQTPVMGVYIVDSY
                     GALYPKEVRKLTRHFQDHLSPYGKLTGIHAHNNQQCAFANTIEAHDLNAKMLDATYYGM
                     GRGAGNCHLEALLGYFNGKKYHVEPVLDLVGSDMLVMKDQEPTWGYNTSYLIAGLANAH
                     PRDAIAATKKKDTNFVEQYKFQIYK"
     CDS             13160..13675
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DHQ_synthase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1183:3-dehydroquinate synthase (Score: 121.2; E-value:
                     7.5e-37)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2992"
                     /sec_met_domain="DHQ_synthase (E-value: 8.5e-51, bitscore:
                     170.7, seeds: 76, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVDASISGKTAVDLQAGKNLIGAFWQPSLVVADTQVVTNLPADIF
                     AEGMAEVIKSDLIANAGIVEMIRQNTIKERIDQMVASCIKMKRDVVEQDEYETKGLRKV
                     LNMGHTVPHAIEKLSNYSISHGVAVATGLVWEAKIACHLELCASGLVDEIRAAVDAYQL
                     YYDVPYTV"
     CDS             13679..13819
                     /locus_tag="ctg1_2993"
                     /transl_table=11
                     /translation="MVEAMKNDKKNDDSRIDFVFPIEYSKWEERRLEQKELMNIIKTLN
                     I"
     CDS             13822..15003
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1079:oxidoreductase (Score: 76.5; E-value: 3.9e-23)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2994"
                     /transl_table=11
                     /translation="MEQVTIGMAGAGRATELHIMALKRFLGVPVRLKTIVARRKEQLEE
                     AQRLYGFEQISYSFDDMINDPEIDVIDICTPPYAHEEMIEKAMMAGKHVICEKPLTGYF
                     GTPGDEEPIGDKVPKRVMYLKMLEQIRYLRTVIKKTGKKFMYAENFVYAPAVRKTAEII
                     KAKKSRILFMKGEESLKGSSSPVAGEWSKTGGGTMIRTGAHPLSAILWLKQQEAQARGV
                     EIKVKSVLGVMDRITPQLNEYEHRHIAARPHDVEDFGTIILDFTDGTKAVVIATDTLLG
                     GSKNYVELYCNDAAINCNLTMSNLMSTYFLDEDNLDDVYISEMLPSKTGWNNPFLEDEI
                     IRGYTDEMRDFMECVYYDREPQSGFTLAYDTIKIIYAAYMSAELGNKVELNAF"
     CDS             15006..16040
                     /locus_tag="ctg1_2995"
                     /transl_table=11
                     /translation="MDFLKKLPTPEELAKIYPLSKGMAKKKLEHDKEIKKIFSGESKRL
                     LLNIIVCSADRMDAVLEYAARLAEIQKEVVENILIVPRVYTSKPRTIGKGYMGMIHQPY
                     IGQGEDLSMGVAAVRNVHRQVVEETGLFPSDELLYPETIHYLADLLGYAVIGARSVENQ
                     QHRLVASGLNIPVGLKNPISGSINVMLNAIETAQHPHHFIFNGWEVMSKGNEYAHGVLR
                     GYLEEGGAATRNCDYEHLSEICDRFAVRNVENPAVVVDCNHSNSDKQYMRQIDNAMEVL
                     GLMKEYPKIKKLVKGLMIESYLEDGNQPIDGGVYGKSVTDPCLGWEKSKQLIYDINEKL
                     EGLK"
     CDS             16037..16252
                     /locus_tag="ctg1_2996"
                     /transl_table=11
                     /translation="MSERPKKIFCFDNYPEAKMALGKVTYPVIIKPYECEDKTFWFEAS
                     DYGKAGQVLYDAFEHTRNGWVMIEEH"
     CDS             16255..16953
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1170:metallo-beta-lactamase family protein (Score: 99;
                     E-value: 4.4e-30)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_2997"
                     /transl_table=11
                     /translation="MNSYKAFIEEREVSIYRFPYELVDSNMFFIPSGDTGIVFDPNENE
                     ELLRVFQELGTRSVEIVLTHEHYDHTTGVKWLQSKIETRLFCHRACAEAIATEKGNDPK
                     TLGYILTLRDAVDGGHRRENFLATAKRYMLRADEAFDGDCGLKVGELVLRCHPAPGHSP
                     GSALYFLGETAFFSGDSLIQHTPTIVHLPGSDRRAYKQETKPYLRSLDKDMMVFPGHGE
                     PFKLGEAEFL"
     CDS             17076..17498
                     /locus_tag="ctg1_2998"
                     /transl_table=11
                     /translation="MALDLYIFYFYFRDLNLKLFQVMNMSEFYSDFLYRYQTEAAPLNV
                     SIDSFCLREGVEYRNFIRWYRDNKKRLRESEMADIRISAIKVTGAPALTAPVNPPIAFC
                     TVSEFHLKLSNGIEIHKPDSHLEDITNLLSSLSRVC"
     CDS             17492..17824
                     /locus_tag="ctg1_2999"
                     /transl_table=11
                     /translation="MLGLSSHMNFYLCEGFVDMRKGIATLSELVRRKLHKDPESGDVFI
                     FLGKDRRNIKILRHEYNGYVLYWQKLNRERFLLPVFNSDLNQYEISWDKLVVLLQGTVR
                     KGLLVG"
     CDS             17988..18884
                     /locus_tag="ctg1_3000"
                     /transl_table=11
                     /translation="MSYAINVPVWRLRLANSEQEKSDLREALKALQQTRADDLFELERQ
                     KRQLYGRSSGKVKSLKKLQERSVKEDKDDFDGFNPPGLPPHEGHALLDTMRSSDALVGQ
                     AAKSKPHRSDYGKNATQIESTVMHYCNRDQVPADARPINVRHWILYKMDWNVCKHVFEI
                     PRLIDSEGAISNYYAPFEGDEALHPFENVLPGHHVGMDMIAQIMVDKYQYSLSSERGVA
                     RFSDAGAKFSSSTVLSWIQKHTDLLGKQETPLRNLLLSKDSFCSVMGLLNWSESKTRKR
                     ERWNTRSSISGAARIRP"
     CDS             18836..19072
                     /locus_tag="ctg1_3001"
                     /transl_table=11
                     /translation="MEYKKQYIWGSKNPALKVAYYLYDRGSRSMAVAENHFKDFFGNIT
                     TDGYNVYKLFDRHRKGVTRYGCMAHVRRKFVDA"
     CDS             19069..19578
                     /locus_tag="ctg1_3002"
                     /transl_table=11
                     /translation="MNTDERSVEVVNLISELYWIESDCKIHFLSEDERRKERQQRALPV
                     LDKLWQIIKPIFDATQDAASNLFIKAIRYAVAEWESICCYVNNGKAEIDNNTAERMMKP
                     ICLGRNNYLFCGAEPGAKNTSLLYSIIETCKMNGLRPVKYIADVLRKLVAGATNYAALL
                     PINIAK"
     CDS             complement(19604..19828)
                     /locus_tag="ctg1_3003"
                     /transl_table=11
                     /translation="MSMSQKQGLYRSALFLNTLLYRSNIPNIYQYMPIFPLNRQYISIG
                     GENRIDNLRMFFVSTHCTASLVFTASSLL"
     CDS             19865..20245
                     /locus_tag="ctg1_3004"
                     /transl_table=11
                     /translation="MYPDCIVYTSSFGKEALGSDKLNFSRYHNDPVIWMGDNVTVLHEN
                     DKVEIFPGIFVEVFETPGHDKSCLTYKVENNVFSGDSYIPGVKVIASFPNSDREDARIS
                     KERIMELTKDCSLYPGHGNIYE"
     CDS             20352..21602
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) DegT_DnrJ_EryC1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Aminotran_1_2"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1056:DegT/DnrJ/EryC1/StrS aminotransferase (Score:
                     256; E-value: 1e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_3005"
                     /sec_met_domain="DegT_DnrJ_EryC1 (E-value: 7.5e-85,
                     bitscore: 283.4, seeds: 38, tool: rule-based-clusters)"
                     /sec_met_domain="Aminotran_1_2 (E-value: 1.3e-05, bitscore:
                     22.6, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDKTIYLCLAHMSEEGIEQKYVKEAFDTNWVVPLDPNVNAFEEDL
                     KRFVGEGKEVVALSAGTAAVHLALLACGVGQGDEVIVQSFTFCASSHPVTYLGAVPVFV
                     DSEKETWNMSPELLEEAIKDRIAKTGKKPKAIVPVALYGMPYDCTRIMEIADRYAIPVV
                     EDAAEGFGSRFKGQVLGTFGKFGVLSFNGNKMITTSGGGALICKDAESKNQIMWYATQA
                     REAYPYYQHEAIGYNYRMSNICAGIGRGQMTVADKHIAHHRHVQALYKELLKDVEGVLL
                     HEAPSADYDSNFWLCTITLDSSLRIKGQENAYKDVVRTAVGGAAGVIHAVDCATTDCQP
                     NENVEALRAFMLGKKIEARPVWKPMHKQPVYKDAPAYINGVSEAIFKIGMCLPAGPWVT
                     DEDVYYIVECIKEAIVK"
     CDS             22077..22577
                     /locus_tag="ctg1_3006"
                     /transl_table=11
                     /translation="MPLFYYARQSSLATKEGAKLWHLSLKKVGRAVDAQQLAEVIAEKS
                     SLTPGDVHNVIRNLMTVMRSQLLNSRTVRLDGLGTFTMKARTRGKGVVKSEDVNPNQVT
                     ALRCQFTPEYTRPAAIGTTRALLQGVEFEKWTGVVTDGKDDAGDGGNSGGGSDGDQGEN
                     PLG"
     CDS             22610..22705
                     /locus_tag="ctg1_3007"
                     /transl_table=11
                     /translation="MKKNVWDKILKVVIAVASAILGALGANAMNV"
ORIGIN
        1 catccttcgg ttttagctat tgactccaca atgcagttgg cacaacagac aggatatcgt
       61 gttgttagtt tcggttacat gcaaaaaaac atagagaatc atatagatgg tgcaccatgg
      121 gagtttcttt ctatgattga tggggcggaa tatgtgatga cggattcctt ccatgccaca
      181 gtgttcgctt tactatttca taaaaatttt tatgtgtttg ataggcaata tgtgcataaa
      241 caatctcagt catcaagaat aacagatttg ttggcattac taaatttatc cgatagatat
      301 aatacaattc atattgataa taataatata aattattcgc ttgtagatga agttttatcg
      361 acttatagac aagagtatga caatttttgc aaacagattt ttagaaatat tatatgaata
      421 cggcaattgt taaaagggcg tttagataca tttttcgggg aataccacgg ccacatatta
      481 gtattgcggt aaaaaatttt acgacacgac gtcttgaagg aagaaaaatt ttaataactg
      541 gtggtggcaa gggaataggt tattggattg ccaaaaaatg cgtatctgaa ggagcaaaag
      601 tgttgatttg cggaaggcaa gaagaaactc tccgcagagc ttgccgggaa ttaggcgaat
      661 cttgtcaata tattaagttt gatgtttcta gtattattga cataccatct tttttaaatg
      721 aagcgttctt aagaatgaat ggtatagata gccttgtgag taatgcgggt atatctttac
      781 atgagggctc ttttaaaaat gtaacggaga gtggttttga tgctcagttc aaagttaatt
      841 ttaaggcacc atattttctt gctaaatatt tcgttgaaaa aatcgaaaat gaaaagatag
      901 gctctgctaa tattctattc gttacatcgg aacgtggaag cttttgtact tctataccat
      961 acggccttac taagtcatct ttaaaaagct atgttggtgc attgtgtcgt tattattgtt
     1021 ttaatgaacg tatacgagta aatgcaattg ccccaggagt aacctcatct gaaatgacag
     1081 gatatagtga aaacggagat tttcaaactg atgacagccc aaacggccgt atatttcatc
     1141 cggcagaaat ggctaatgtt gcttgcttct tactcagtga tgaagcatcg tgtattagtg
     1201 gagagactat tcattgtgat tttgggagac atcagagtgt aatcgattag tataggaaaa
     1261 acatgaacat caaataggtt ttttatgatt gatagcatta tttcgtgttt aaacgctaaa
     1321 ggtgtagtaa gatttgttaa tacaactaca cagataaaag aaaaaatatc atacccttcc
     1381 aatatagaat ggtattatat tgaagatgtt agaagtgctg tttttaacgc atatggaatg
     1441 tcaaagatta gccattctcc agttgctatt atagtggagg aggcctactt acctaataca
     1501 tatactgcac tcacggaagc atggcttcaa agagtgcaag tgattgtatt ggcactgaat
     1561 agtatgaatt tggatagttc gttctatttg aataggtgcg ttgatgcatc tatcctaatc
     1621 gataatgtgg aaacaattga aggtgtagta tgtaatgcta ttcaacatca taatcttctc
     1681 ttataaaaat aaaggaggag gtaaacgaag aaaaaaagat tgattatacc aatctatttt
     1741 caattataga tttgtgcgcg aaggataaaa aagttttatg ttataatcct caatatggta
     1801 ataaagacta tgaatttata ccaccagagt ataaatatgg tgttatttca aaatatgtag
     1861 gacaacttat aggaggaaag caatcggttt tatgtattcc agaatactta ttggcattgg
     1921 atacaaatat atttaatttc agggattttc ctgacggttt caaattaatt gtaaaatact
     1981 ccgacggtgt ttgttggggg cgtcttaata cttggatgca gaggaataac atcaacacat
     2041 atgttgtaga cggtcgttcg tttgaatata cgacaatgaa ttttaagccc aattatgcaa
     2101 tcttagtaaa atagaggtta tgaagacaaa gataaaacag gtacagcaga ttgtatcatt
     2161 attaaaacaa aataatatac gacattttgt cctttcgcca gggacgagac atgtggcctt
     2221 tgtacatatt gttgaaatgg atcccttttt taggtgttat tctatcgtag acgagcgaag
     2281 tgccgcattt tttgctcttg gactctctga ggcattagat gaacccgttg gttttgcttg
     2341 tacatcagct actgcatcat gcaattatat gccggctatg aaggaggctt atgagagaaa
     2401 tattcagttg gtagcattaa cttcagacaa gcaaagatat cagagatttc atggtgttag
     2461 tcaagtaata aaccaagttg atatgttcgc accatattgt cgatatgctg tagatttgcc
     2521 cgaagtgaat gattccatgg atgaatggtt ctgcaatcgt tgtattaatg aagcattgtt
     2581 agaaatggat catcatggaa gaggccctat tcaaataaac tttctagagc ccagtagcat
     2641 tgatgaacta tccatctttt acgatggtaa tatgcctgtg tgtcgaaaaa taaatagaat
     2701 tgaggattgg tcacaaatta atgagtggaa aaatgtactt gcagcaaaaa aaagaattct
     2761 tgttgtttgt ggtcagtatc aggagtttac agggtgttta aggtcaagta taagaaagtt
     2821 ttatgagaaa tataattgtg cggtatcatt tgatgcgttt tcaaatgttg cagacaaaga
     2881 ctttattcaa acaatgttgt tgtcaataac acttaatcag aaggaactgc taagtttgaa
     2941 accagatctt attattacat ttggaacaaa atatttctca gacattgtct cacgttttgc
     3001 gggaatggga attgaacact gggaaatcaa ttttgaaggt cgtatttttg acacaagcag
     3061 gtcgcttact aaaatattcg agtttactcc agaggaattt tttgacaaag tttcctataa
     3121 tatcacgaca aacgataagc agtatgataa attgtggagg gctttgaatg aaagccgaga
     3181 taattctata gatgaattta ctaattatta tgttgcaaaa aaggttttgg aatctttgcc
     3241 cgaaggcagt aatgttcatg caagtgttct gaatagtatg aaattcacaa atatgagtaa
     3301 gctcccacaa aatactattg caacaggtaa caattgtgca gatggaatag atggagctct
     3361 ctctactttt attggccaag ccgaagtgct tgatagtctc tcgctgcttg ttatagggga
     3421 tttgagctat ttatatgatc taaatgcagc tatccatgac tttaaaaata acactagagt
     3481 tttactcatt aataattttg cggggggcga attccatttt aatattggga agaaaaaaat
     3541 atccacactt gaacagcata tagcggctgg acatcataca aaaatacaag atgctattgg
     3601 tttatctaat tttcaataca tagctgttca taataaaggc gaattagaag aaaaactttc
     3661 actttttttg cgggaaagtg aaaatccaat tttaatggag gtctttacca accctgaact
     3721 cgatggttct tccttgaaaa aacttattcg aaataatata aaaatgacac cagaaaggct
     3781 gatagctggg ttcgttaaca agttcctaga ttgtaggact aaatatgcga taaaaaaatt
     3841 cttacataga taaaagtaat ataatctttt agtattattc gattaatgcg tgtattaata
     3901 tacggtttta ccggaaacgt tttagggggg attgaggtat ataccctcaa tatgagcgaa
     3961 tacatgtctg atgattgtgt gtttgattat attgttgacg gggatgaatg tgcatataga
     4021 gaacggataa cgaaaagagg tggaaaaata ttttttgttc cttgggtaag aagacatcct
     4081 cttgggtata taaacaaatt gtggcgtatt tttggtgaag agaagaagtc tggcacaaat
     4141 atattatatc atcaactatt tacaatgtct aacctcatac cagatgttat tgcaaaactt
     4201 aggggatata aggtaatttt acatgctcat aataatggac tacagaaagg cggaagaatg
     4261 tatttgatgg cacacaattt aggaaaaatt ctttcgagat tctgtggttt tgtgatgttc
     4321 acaaattccc agttgtcctc agattatatg tttgggaagg gtgttaattc gaagcttata
     4381 tataatgcta ttgatgttgg gaagttcgct tttaaacaag aacatagaga ttgtataaga
     4441 aaagaattgg actgtcagag caagacggta ataggatttg ttggtagact tgtagaccag
     4501 aagaatcctt tgttcatgct taaagtcttc gctgaaattc ataaacttcg tccgaatagt
     4561 gagctttgga taattggaga aggaattttg agaggaaaaa tggaagtaga aataaacgag
     4621 caagggatat gttcatcagt aaaatggctt ggacgaagag aggatgtcaa tagattgatg
     4681 caaggaatgg atcttttgtt acagccgtca gtatttgaag gcttaggaat agtacttgtt
     4741 gaagctcaag caacaggcct tgccgttgtt tcctcagaag tcgttatacc aaaagaggca
     4801 gtgatttctg atagaataaa gctcttaccg cttagcgaaa aatctgcata ttgggctgct
     4861 gaaagtgtta atcttttaga ttcgtgctgt gaatcttatg atagaaccaa tgcaatagtt
     4921 ccagattgtt acaatataca gcatgaggca aagagacttg aaagcatgtt aaaagaactg
     4981 attagttaat aagatgatta tacctgttaa aaccagtaag tggttcactt attatctatt
     5041 atttctcccg ttagtaatga tgtacagtgt gcctggtact ggaatacgga ttcctacgct
     5101 tttgacagca attgcaatgt tgtattctct cttgcagtta gccaataggc atatgagagt
     5161 gccaatttat atgttattac cattgttcat gtacttgaca tatgtgatgt ttaagagttc
     5221 tttacaactt gcatttcttt gcggcagtgt gataattatt atatcggcaa tctgtacagg
     5281 tatagtaaat gtttttttat taagaaaagt actggaaaag gtcgcaattg tcgctgcatt
     5341 ctgtgtaatc ttccagcaaa tcgttcatat cctgacaggc atacatttcc atttttacct
     5401 ccttcctttt tttgcaaatg atttgttgga acaatacaac aatgcgatta ctaccggagc
     5461 tgttgaggga atgtataggc catgtgcatt tttcttagaa cctgcacagt attcacaata
     5521 ttgtacaatc ggtcttgggt cttgtttgtt tacccataga ccaaagacga agaatgctct
     5581 ttttatttct cttggtatat ttgcaagtac ttcaggaatg ggatttgttt cagtgtttgc
     5641 tatttggggg gcctgggctc tttcaaggca aaaaactaag aaaaacttta tcaggagttt
     5701 acctgtaatc cttatcgcac tttttttggt gtttttttta ttagacaata ttagttttac
     5761 acataatatt ataaaccgtt ttacttcaac ctcaggtgat gattataatg ccattaatgg
     5821 gaggctgttt tggtgggata catattttgg tgattttaat gtatctgatt ttttaacagg
     5881 ttttggcttg gataatttac ctgatggagt ctattttacg ggttttatga aactattata
     5941 ctgttacggt ttgataggaa cgacactatt gctactattc cttggcatgc taataatcaa
     6001 agcggacatc tttgtaaagg tgtgtacatc tctatacacg ggattgctgt tttttgctga
     6061 tttgacttat tatcataatt taatctttta cataggagta tatcttgcat tgtatatttt
     6121 taataaggaa agagtcaata ttgcaggaac attgaaagcc tgaaatggat ataaaaaaat
     6181 ggataaaaat aattctttta atcttcgtgc ttggttatgg ggtaagatga catctttata
     6241 ccccaaatat cttaaatggc attttaagat ggatataggt gagaatgcag taatagcacg
     6301 gaccgcagtt ctggataaaa acattaaccc cccaaggtgt tcatattggt aaaaatacat
     6361 gggtgttgag agatgctatt attctggcac atgatcactg cagaggcaaa aatgggaaag
     6421 gaaggttatt tgacactcgg attggaaaga attgtgtgat tggtattcgc agtatcattc
     6481 tgcccggtgt aaccgttgga gatcattgcg ttgtagccgc aggtgctgtt gtaaccaaaa
     6541 atgccccccc aactccataa tagccggcaa tcctgcggta gttattaaga cgggcgttgt
     6601 gataagtgat ggagggcaaa ttattgaacg cggagaaaaa atataaatat gtataagcac
     6661 ttctttaaac gtccatttga ttttattatc agtttggtcg ctctgatttg tcttagcccc
     6721 atattgttgg ctgtgaccat ttggcttcat tttgccaaca aaggggctgg agcattcttt
     6781 attcaagcca gacccggtaa ggatgctgag atattcaagg tgatcaagtt taaaacaatg
     6841 aaggatgagt ttgacgaaaa aggcgaaccg ttacctgatg aggtcaggct taccaaagtg
     6901 ggaaaaatag tacgctcaac atcattagac gaattgccac agctgcttaa tgtgttgaaa
     6961 ggtgatatgg cattgatagg ccccagacct ctgatgccgg aatatctgga gctttatacg
     7021 cctgagcaaa tgcgccgtca cgaggtaaga ccaggcatta ccggatgggc acagatacac
     7081 gggcgtaatg agttgccttt taccgagcgc ttcgagtatg acgtgtatta tgtggatcat
     7141 ctgacctttg gcttagacct gaaaatattc tttatgacca ttgtcaaaat tttcaaaaga
     7201 gaaggaatat cccagaaagg tcaggctaca gtagagacat ttgatggaac aaactaatat
     7261 ggaataacat aatgaaacat ttggtaataa taggcggcgg aggaatgggt aaggatattt
     7321 accattcagc caagcattcc attggttatg gaacagagta tgacataaaa ggattcatag
     7381 atgacaatct gaattccttg gatggttgtg aggggtatcc gccagtctta gatacaataa
     7441 agaactatca gccttcagaa gatgatgtat ttacctgctc tatcggtaat gtgaaaacaa
     7501 agagaacgct ctgcgaaatg ataaaagaca ggggggaagt tcattacctt gctacatgag
     7561 acagcccaat tgggagaaaa tgtgaaactt ggtgatgggt gtatcatcga tagtcacgcc
     7621 cacataggat cagatacgat tataggcgag aattgtttgg tgcagacgtt tgctggaatt
     7681 ggtcacgact gtagggttgg tgattattgc cgcattgatg tcagggcatt tcttgttgga
     7741 ggcgtacgaa tagaagaaaa tgtaactata cataccaatg ccatattgaa ccaccatgta
     7801 gtagtggaga aagatgcagt ggtagctgca ttaagctttg tggttagaaa ggtcaaggct
     7861 ggaactaccg ttttcggtaa tccagccaaa ctgttgaaat attaaataaa acaagtaata
     7921 ataattgaat tattgaaaat tatggaatta aacgaattta ttgagaattt tgcagagcag
     7981 tttgacgaca ccgatgccag cgagattaag gcagacaccg tttttaagga actggacgag
     8041 tggtcatcgc ttgtggctct gagcgtgata gctatggtgg acgaggaata tgatattacc
     8101 atcaagggtg atgaaatctg gaattccaat accgttgagg acttgttcaa cgctataaaa
     8161 gccaaagcat aaacaatatg tataatccat attctctaac agggaagacc attctggtga
     8221 ccggtgcttc gtccggcata ggccgtgcaa cggctatcga atgtgctaag cttggagcaa
     8281 aggttgtcat tacagcccgt aatgaggata ggctgaaaga aacgcttgat acgctggagg
     8341 gtgaaggaca tcagatgatt tgtttcgact tgtctgaaac ggagaaactg aatgactttg
     8401 ttgcaagcct tcctccagta caaggctttg tgagcaatgc tggaactaca ataatagctc
     8461 ctattaaatt tattaaggaa gatagtctcg aaggattgct acaagtaaat acggtttccc
     8521 ctattctact tttgcaaaga ctacttaaga aaagaatatt aggcaagggc tcttctgttg
     8581 tattcacaag cagcatggct gcacttggaa aaggcacacc cggtaatacg atgtacagtg
     8641 catctaaagg tgccattagt gctttcatcc agaatgctgc actggaattg agtgcccaga
     8701 gaatcagggt aaatgcagtg tgtccgggca ctgttgacac tccccttatt catagtggtg
     8761 gcattactga tgaacagttg agtgaagatg caaaaaaata tcctctcggc tatggacagc
     8821 ctgaagacat tgcattggga atagcatacc tcctttcaga tgcagccaag tgggttacgg
     8881 gaacaaatgt aattattgac ggagggttat ccgtcagttg ttgaaacaag gattactatt
     8941 atggcaaaaa taaaaataaa caacgtaaga atcaagggca tcgcagcctg tgcaccatcg
     9001 aaggtggagg agaacagcga atatccttac tttgacgaga acgagttcga aaacattata
     9061 ccaagtatag gcgtggaacg tcgccatgta gctaaggaag gtcagacgtg tgctgacttt
     9121 gcccagcgag ccgctgagaa actgatggaa gagttgggat gggagaaaga aagcatagac
     9181 ctgctcatct ttggctcccc ttccaaagac tatatccagc cggacacggc ttgtgtgctg
     9241 caaggcaagc ttgacctgcc ggaatcgtgc atggcattcg acatgactct gggctgcaca
     9301 ggctggacat acggcatgac caatgcctgt tcactgatgc agacagggtg catcaagcgt
     9361 gtactgttac tcaatggtat acagggttct gcggagagct gctactacga caagaccggc
     9421 tacccgctgt tcagcgatgt ggccactgct actgctttag aatatgatcc aacagcggca
     9481 cccatctatt gtgaactggg caccataggt aaacagtttg atgccattct tgttcctgac
     9541 ggaggtcgca ggaatcccgt gacagaaggg agtctgaaac tggtggagta tgaaaagaat
     9601 gtgaagcgaa accgtctgca cacctttatg aagggaatgg atgtgttctc ctttgccctg
     9661 aagactgccc ccaagagcac caatgcagtg ctggagtttg caggtaagga aaaggacgag
     9721 attgactact tcttcttcca tcaggccaac ttctatatgg tgaagaaaat catcaaaaag
     9781 ctgaagatag acccggagaa ggcacccata gtgatgaaag acttcggaaa cacaggtgct
     9841 tgcagtatac cctttacgat ggtgataggt tgcgcagaga aactgcgcaa cggaaagcat
     9901 accaatgtgg gctgttcgtt tggcgtgggt ctttcatggg gaagcttgtg ctttgagaca
     9961 gaaaacttag tgatacccga actgcaaata tacgattaat atgagaagtc agttagcaga
    10021 tttgttttat aagaacgcag cagagatgcc tgataagcag gctatctggt gcgacggaaa
    10081 aacagccacc tatcaagaga tggcaaatcg ggtgagccgc tattcgaact accttgttgc
    10141 gaaaggtgtt cagtatggtg accatgtggc catccccatg aacaatagca tagaatcagt
    10201 tgcgctgttt ttcagtgcgg cagacctggg cgtatgtctg gttccgctga accctacact
    10261 ccctttggag tcaattaagg tggccatgaa gtcgggcgac atgaaacacc tgatagcccg
    10321 caagagtttc ctgaacgaat gcgagaagaa aggtggagtg gacgtgcctg gcatcaccgt
    10381 atgcctagac ggagagtttg aaggagcatt ccctttcagt gaggtggcaa cgatgcctac
    10441 tacacgtcct gcctgtgaga atatcaaggg cgatgagagt ctgatactga ccatgacctc
    10501 cggctctacg ggaacaccga agccaattga catttctcag cagaacaaaa tagaccgctc
    10561 gctggctcat atccgagtgt atggactggt gaaggaagac agaatactgg ctgctacacc
    10621 gctgtaccac tccttggcag agcgcctggt gattatgccg ttgcttttgg gtgcgacctc
    10681 tatcctgctg ccacgattca ctccggcctt gtggctgaag tgtgccgcag aacagaaacc
    10741 gacgtttacc attgcggttt ctgcccagtt ggcgcagata cttgaactgc tgaagcagga
    10801 gaataccgaa agtatagaca gcttccacac aatcgtttct tcatcagccc tgctggagga
    10861 gaaggtgaag ctggaactga tagaccgttt gcagtgcgag ttccacgaga tgtatggcac
    10921 ctcagagaca tctacggcta ctgatatttg cttccagaag gcccgtaaca agcaaaagag
    10981 tgttggcctg ccggatgaag cggaagtgaa gatactacgt gacgacgagg ataccgaatg
    11041 cgctgtgggc gaagtgggag agattgccgt gaagtcgaag ctgacctgta agggctacta
    11101 taagctgaaa aacatgatgg atatggctac caccgaaggg ttcttccgta ctggtgactt
    11161 aggctatatg gacgaggatg gctatctcta ctttgccgga cgcaagaagg agttgattat
    11221 cacaggagcc atcaacgtat atccaaatga tgtggatgcc gtagtgaacc agttgaccgc
    11281 tgtggaagaa tgcgcagctt tctcctatcc tgacgaaagg cttggtgaag tagtggcact
    11341 ggctgtggtg gtgaaggaag attgcgaact gacagagcgc accatcaaaa cctattgcgc
    11401 caagaacctg gcagacttcc agcagccaca caagattttc tttgtggata tgctaccgaa
    11461 gaacacaatg ggtaagctgc agcgcaaccg catactagac catataagaa atgtaggaat
    11521 agacaaataa aaagaaatta cgactatgac agatattaaa gaattcgtga cagaatatat
    11581 tcagcgcgaa tacaccgtac ctgaagacgt cgatattatg actctcaact atattgaggc
    11641 aggctatatt gactctatgg ctttcattca gtttatctct accatcgaag acgagtatga
    11701 tattgagttt gaggtggagg acatagagaa tcctaaactg aggatagtag gcaagttgat
    11761 tgattttatc caagccaaga tagacgaaca gcattaagac cgtcatgaga aatatagaag
    11821 gaataaaaat agtagatgcc actatccgtg acggggggac tggtgaacga cttcttcttt
    11881 accgatgagt ttgtaaagaa ggtctatgaa accaatgtgg ctgcaggtgt tgactacatg
    11941 gagtttggct atcgtgcaga caagaagatg tttgatccca gtaagttcgg taagtggaaa
    12001 ttttcctcgg acgaggacat cttcagcatt gtgggtgaca acccgacggg gctgaaactg
    12061 tgtgtcatgg cagacgttgg acgctgtgac ttcaagaacg atatccacaa gaagtcggat
    12121 agtccgctga gccttattcg tgtggctacc tatatagaga ccttttcgga agctatcgag
    12181 atgatagaat ttgccgccaa gcaaggctat gaggtgactt gtaaccttat ggccatctca
    12241 aaatgtacga tgatgcagtt gtcgaaagcc ttggatgcac tggcccagac accagtgatg
    12301 ggcgtgtata tagtggacag ttacggagcg ctctatccca aggaagtccg taaactgacc
    12361 aggcacttcc aagaccattt gtcaccctac ggcaaattga caggcatcca tgcccacaac
    12421 aaccagcagt gtgccttcgc caacaccata gaggcacacg acctgaatgc caagatgctg
    12481 gatgccacct attatggcat gggacgaggt gctggcaact gtcacctgga ggcattgctt
    12541 ggctatttta acggcaagaa gtatcatgtg gagcccgtgt tggacttggt gggaagtgat
    12601 atgttggtca tgaaagacca ggagcccact tggggctaca atacatcgta tctgattgcc
    12661 ggactggcca atgcccatcc gagggatgct attgccgcca caaagaaaaa agatactaat
    12721 tttgtggagc agtataagtt ccagatatac aagtaagcgt ggaaacgata gtggtaaaca
    12781 cctcaaggaa gtaggatgtc ctgttggggc agggagtcat tgctgacttg ccccggctgg
    12841 tagagccatt ctgtaaagga gggaaggtgg gggtcatcac ggatgatacc gtagatgccc
    12901 tgtatgctgc aaaggcggta tgggcaatgg aacaatacgg atatgatgta tgtaaatacg
    12961 tcatcccata cggagagagt tccaagaaca taaatactct gtcaggtatt ttggagtatt
    13021 ttgcttcctg tcattttacg agaaaggaca ttttcctctc cattggtggt ggtgtgatag
    13081 gggggacatt acgggagtgc ccgctgcact gtatatgcga ggcatccatt ttattcaaat
    13141 gcctactacg ctactctcta tggttgatgc ctcaataagt ggcaagacag ctgttgacct
    13201 gcaggcaggg aagaacttga taggcgcttt ctggcaacct tcattagtgg tggcagacac
    13261 acaagtggta accaacctac cagcagacat ctttgcagaa ggcatggcag aggtcatcaa
    13321 gagcgacctg atagctaatg ccggtattgt ggagatgata cgacagaaca caatcaagga
    13381 gcgtatagac cagatggtgg ccagttgcat caagatgaaa cgcgacgtgg tggaacagga
    13441 tgagtacgag accaaaggac tccggaaagt gctgaacatg ggacataccg ttccccatgc
    13501 tattgagaaa ctctccaact atagtatttc acatggtgtt gctgttgcaa cgggactggt
    13561 atgggaggct aagatagctt gtcatctgga actgtgtgct tccgggcttg ttgatgagat
    13621 acgcgctgcg gtggatgcct accaactcta ctacgacgta ccctataccg tatagaatat
    13681 ggtggaagcc atgaaaaacg acaagaagaa tgacgacagc aggatagact tcgtattccc
    13741 tatcgagtac agtaaatggg aggaaagaag actagaacag aaagagttaa tgaatattat
    13801 caaaacacta aatatctgaa tatggagcaa gtaaccattg gaatggcggg tgccggacgc
    13861 gctacggaat tgcacattat ggcattgaag cgctttttag gtgtgcctgt caggttgaag
    13921 accatcgttg caagacgtaa ggaacagctg gaggaagccc agcgtcttta tggctttgag
    13981 cagatttcgt acagctttga cgatatgatc aacgaccctg agatagatgt catagacatc
    14041 tgtacgcctc cctacgctca cgaggagatg atagagaagg ctatgatggc aggcaagcac
    14101 gtgatatgcg aaaagccgct gacgggctat ttcggaactc ccggcgatga agagcctatc
    14161 ggtgacaagg tgccgaaacg cgtgatgtat ctgaagatgt tggagcagat acgctacctg
    14221 cgcactgtta tcaagaaaac cggcaagaag ttcatgtatg cagagaactt cgtgtatgcc
    14281 cctgccgtga gaaagaccgc agagattatc aaggccaaga agagccgtat cctgttcatg
    14341 aaaggagagg agagcctgaa gggatccagt tcgcccgtgg ccggagaatg gagcaagacc
    14401 ggcggtggca ccatgattcg taccggtgca catcctcttt cggccatcct ctggctgaaa
    14461 cagcaggaag cccaagcccg tggagtagag attaaagtaa agagcgtgct gggcgtgatg
    14521 gatcggatca caccccaatt gaatgaatac gagcatcggc atattgccgc cagaccgcat
    14581 gacgtagaag atttcgggac tatcatactg gactttaccg acggcaccaa ggccgtggtg
    14641 atagctaccg acaccctgct tggcggttcg aagaactatg tggaactgta ttgtaacgat
    14701 gctgccatca actgcaacct caccatgtcc aacctgatga gcacttactt cctggatgag
    14761 gacaacttgg atgatgtcta tatttcagag atgcttcctt ccaagacagg atggaacaac
    14821 cccttcctgg aggatgagat aatacgaggc tatactgacg agatgcgtga ttttatggag
    14881 tgcgtgtatt atgaccgtga gcctcagtcg ggtttcactt tggcatatga taccataaag
    14941 attatttatg cagcctatat gtcagcagaa cttggcaaca aagtggaact aaacgcattc
    15001 tgattatgga tttcctgaag aaacttccta caccggaaga attggctaag atatacccgt
    15061 tgagtaaggg aatggccaaa aagaagttgg agcacgataa agagataaaa aagatattct
    15121 ccggggagtc aaaaagactg ctattgaata tcatcgtttg ctctgcagac aggatggatg
    15181 ccgtactgga gtacgctgca cgccttgcag agatacagaa agaggtggtc gagaatattc
    15241 ttattgtgcc tcgtgtctat accagcaagc ccagaaccat tggtaaaggg tatatgggta
    15301 tgattcacca accctatatc gggcagggtg aagacctgtc gatgggtgtg gcggctgtgc
    15361 ggaacgtaca ccggcaagta gtggaagaga ctggattgtt cccatcggat gagctcttgt
    15421 accctgaaac tattcactat ctggcagacc tgttgggcta tgctgttatt ggagcacgtt
    15481 cggtagagaa ccagcagcat aggctggtgg ccagtggact aaatattcct gttggcctaa
    15541 agaatcccat aagtggcagt atcaacgtaa tgctgaatgc cattgagacc gcccagcatc
    15601 cgcaccattt tattttcaat ggatgggaag tgatgtcaaa gggcaatgag tatgcacacg
    15661 gcgtacttcg aggttatctg gaagaaggcg gtgccgcaac cagaaactgc gactatgagc
    15721 acctgtcgga gatttgtgac cgtttcgcag taaggaatgt tgaaaatcct gcggtggtgg
    15781 tggactgcaa ccacagcaat tccgacaagc agtatatgcg tcagatagac aacgcaatgg
    15841 aggtgctggg cctgatgaag gaatacccca agattaaaaa attggtgaag gggctgatga
    15901 tagagagcta tctggaagat ggcaaccagc ccattgatgg aggagtgtat ggaaagtctg
    15961 tgactgaccc atgccttggt tgggagaagt ccaaacaact aatatatgac attaacgaaa
    16021 aattagaggg actgaaatga gcgagcgacc gaagaagata ttctgttttg acaactaccc
    16081 ggaggcgaaa atggcattgg gaaaagtgac gtaccctgtc atcatcaagc catacgagtg
    16141 tgaagacaag acattctggt ttgaagcgtc ggactatggt aaagccggtc aggtgctgta
    16201 tgatgccttt gaacacaccc gaaatggatg ggtgatgata gaggaacact gagtatgaac
    16261 tcttataagg cttttataga ggaacgcgag gtgtcaatct atcggttccc ctatgagttg
    16321 gtggattcca atatgttctt tattccatca ggggacactg ggattgtatt tgacccaaat
    16381 gagaatgaag agttgctccg agtatttcag gaactgggga caaggagcgt ggaaatagtc
    16441 cttacgcatg agcattatga ccatacgacg ggggtaaagt ggttacagtc gaagatagag
    16501 acgagactgt tttgccatcg cgcctgtgca gaagctattg ccactgagaa agggaatgac
    16561 cctaagacac tggggtatat actgacgcta cgtgatgcgg ttgacggtgg acacagaaga
    16621 gagaactttc tggctaccgc taagcggtat atgcttcgtg cagacgaggc atttgacggt
    16681 gattgtgggt tgaaagtagg tgaactggtt ttgagatgtc atccggcacc tgggcacagc
    16741 ccggggagtg ccttgtattt cttgggtgag acagcgtttt tttcaggcga ttcccttata
    16801 cagcatacac cgaccatagt gcatctgcca gggagtgaca gaagagccta taagcaggaa
    16861 accaagccat atttgcggtc actagacaaa gatatgatgg ttttccctgg gcacggggag
    16921 ccgtttaagt tgggggaagc agaattcctt taaatattgg tgctatgagt aagaagatga
    16981 agattacatt gcttgctgcc atggtggcag ttggtgcttt gtacataatt tgtttgcaat
    17041 tgatttaaaa actaagatat gtaagcactc actgtatggc tcttgatttg tatatcttct
    17101 atttttactt tcgtgactta aacttaaaat tattccaagt catgaacatg tctgaattct
    17161 acagcgattt tttatatcgc tatcaaaccg aggcagcacc tttgaacgta tctattgata
    17221 gcttctgctt gcgcgaaggt gttgagtacc gcaattttat ccgttggtat cgtgataaca
    17281 agaaacgttt acgcgaaagt gaaatggctg atattcgtat tagtgctatc aaagtgaccg
    17341 gagctccagc attgactgct ccagtaaatc cccccattgc tttttgcact gttagcgagt
    17401 ttcatttgaa actttccaat ggcattgaga ttcataaacc agattcccac ctggaagata
    17461 ttactaacct tttaagtagt ttgtcacgcg tatgttaggt ttgagctctc acatgaattt
    17521 ctacctttgt gaaggttttg ttgatatgcg taaaggtatc gccacccttt cggagttggt
    17581 acgccgtaaa ttgcataagg atcctgagtc gggtgatgta tttattttcc ttggaaaaga
    17641 ccgtcgtaat ataaagattc tgcgccatga gtataatgga tatgtgcttt actggcagaa
    17701 actgaaccgt gaacgcttcc ttcttcctgt tttcaattcc gatttaaacc aatacgaaat
    17761 cagttgggat aagcttgtag tgcttcttca aggcactgtt cgtaaagggc ttttggttgg
    17821 ttaaaatgaa tacaaaaaac gctcttttga gtgttgatta atatgttggt tgtcagataa
    17881 acagcgcagt tttttatttg cataatttat taaaaatgag tatattcact tcatgcaaga
    17941 caaagatatt atcaacatat taatctctca attactttcc aaggatgatg agttacgcca
    18001 tcaacgttcc cgtctggaga ctccgtttgg ctaactctga acaggaaaag tctgatctga
    18061 gggaagcctt gaaagctttg cagcaaactc gtgcggatga cctgtttgaa cttgaaagac
    18121 aaaaacggca actttacggt aggagttcag gaaaggttaa aagcctgaag aagctacagg
    18181 aaagaagcgt gaaagaagat aaggatgatt ttgatggttt caatccccct gggcttcctc
    18241 ctcatgaggg acatgccctc cttgatacta tgagatcatc tgatgctctt gtgggccagg
    18301 cagcaaagtc caaaccccac cgttcggatt atggcaagaa tgccactcag atagaatcta
    18361 ccgtgatgca ctactgtaac cgtgatcaag tccctgctga tgcccgccca atcaatgttc
    18421 gtcattggat actgtataaa atggattgga atgtgtgtaa gcatgttttc gaaattccca
    18481 gactgattga ctccgaaggc gctatcagta actattatgc cccgtttgaa ggtgatgaag
    18541 ccttgcaccc ctttgagaat gttcttccgg gacatcatgt aggtatggat atgatagcac
    18601 agatcatggt agataaatat cagtatagcc tctcttcgga gcggggtgta gctcgttttt
    18661 cagatgccgg tgcaaagttt tcctcttcca ctgtactgag ttggatacaa aaacacacag
    18721 atctgttggg caaacaggaa accccgttgc ggaatcttct tttgagcaaa gacagttttt
    18781 gttctgtgat gggactactg aactggtcag aatcaaaaac aaggaaacgg gaaagatgga
    18841 atacaagaag cagtatatct ggggcagcaa gaatccggcc ttgaaggttg cttattacct
    18901 gtatgaccgg ggtagccgca gtatggcagt tgccgagaac catttcaaag atttttttgg
    18961 taatattacc acggatggtt acaatgttta taaacttttt gaccggcatc gaaagggagt
    19021 tacccgttat ggatgtatgg cgcatgtgcg gcgaaaattt gtagatgctt gaatacggat
    19081 gaacgctctg tcgaagtagt gaacctgatc tccgaacttt actggataga atctgattgc
    19141 aaaatacact ttttatcaga agatgaacgt agaaaggaac ggcaacaaag agcattacct
    19201 gttcttgata aactttggca aataataaag ccaatttttg atgcgaccca agatgctgca
    19261 tccaatctct ttatcaaggc gatccggtat gctgttgccg aatgggagtc aatatgctgc
    19321 tatgtgaata atggtaaagc agagattgac aacaatacag ctgaacggat gatgaagcct
    19381 atttgcctgg gtcgtaacaa ttatttgttt tgcggggcag aaccgggtgc aaagaatact
    19441 tctttattat actcaattat tgagacttgc aaaatgaatg ggctaaggcc tgttaaatac
    19501 attgcggatg ttttaaggaa gttggtggcc ggcgcaacga attacgccgc acttttacct
    19561 atcaatatag cgaaataaac ataattttta aataaaaaat aactcaaagt aggctagagg
    19621 cggtgaaaac caggctagcc gtacagtgag tgcttacgaa aaacatcctc agattgtcaa
    19681 ttctgttttc acctccaatg cttatatact gtctgttgag gggaaagatt ggcatgtatt
    19741 gatagatatt ggggatattg ctcctataaa gcagtgtgtt caggaaaagt gcggaacggt
    19801 acaagccttg tttctgactc atactcatta cgaccatatt tatggtataa aagatttatt
    19861 acgattgtat cctgattgca tagtttacac ttcctctttc ggtaaggagg ctttaggttc
    19921 ggataaactt aatttttccc gttatcacaa tgatcctgta atatggatgg gagataatgt
    19981 gacggtttta catgagaatg ataaagtgga aatatttccg ggaattttcg tggaagtgtt
    20041 tgaaactccc ggacatgata aaagttgcct tacctataaa gtcgagaaca atgttttctc
    20101 gggtgattca tatatcccgg gtgttaaagt cattgcctca ttccctaata gcgataggga
    20161 agatgcacgg atctcgaaag aacgtatcat ggaattaaca aaggattgca gtctgtatcc
    20221 cggtcatgga aacatttatg agtaaattat tccgatatct ggaaaggatt tataaagccg
    20281 tttcctttct ttttattccc cactatgtga ggaatccgaa gtttgatcat taaataatca
    20341 catatatatt tatggataaa actatttatc tttgccttgc ccatatgagc gaggagggta
    20401 ttgaacagaa atatgtaaaa gaagccttcg atacgaactg ggtggttcct ctcgatccta
    20461 atgtgaatgc ttttgaagag gatttgaaac gttttgtagg cgaaggcaag gaagtggtgg
    20521 cactttcggc cggtacggcg gcagtacatt tggctctgtt ggcttgcgga gtgggacagg
    20581 gtgacgaagt gattgtacaa agcttcacat tctgtgcgtc ttcgcatccg gtcacttatc
    20641 tgggggctgt tccggtattt gtggattctg agaaagaaac ttggaacatg tctccggaac
    20701 tgttggaaga agccatcaag gaccgcattg ccaagactgg aaaaaagcca aaagctattg
    20761 ttcctgtggc attgtacggc atgccctatg actgtacacg tatcatggag atagccgata
    20821 ggtatgctat tccagtggtg gaagatgctg ccgaaggttt tggctcccgt tttaagggac
    20881 aggtactggg gacgttcggc aagttcgggg tgctgagctt taacggtaac aagatgatta
    20941 ctaccagtgg cggtggtgcg ttgatttgta aagatgccga aagcaagaat caaatcatgt
    21001 ggtatgccac gcaggctcgt gaggcttatc cttattacca gcatgaggcg atagggtata
    21061 actatcgcat gagtaatata tgtgcaggta ttggtcgtgg tcaaatgacc gttgccgata
    21121 agcatattgc acatcaccga catgtgcagg ctctctataa ggaactgctt aaggatgtgg
    21181 agggggtatt gctgcatgaa gctccttcgg ctgattatga ctctaatttc tggctttgta
    21241 caatcactct ggattcttca cttcgcatca aagggcagga aaatgcttat aaggatgttg
    21301 tcaggactgc cgtaggtggt gctgcaggtg tgattcatgc cgtagattgt gctacaacag
    21361 attgccagcc caacgagaat gtggaggctt tgcgtgcttt tatgcttggc aaaaaaatag
    21421 aggcacgccc ggtttggaaa ccgatgcaca agcagccggt ctataaggat gctccggctt
    21481 atatcaatgg ggtatccgaa gctattttta aaatcggtat gtgccttcct gccgggccgt
    21541 gggtgactga tgaagatgta tattatatcg tggagtgtat aaaagaggcc atagtaaaat
    21601 aatagatgaa aatacagctt ttttaactac gaccttgaca acgctgtcgg ttgccaatac
    21661 gtttgtcaat gcggatttca tctataccgt tgtctgttcc gttctagtct tctgcttctt
    21721 caatttctgc aagcgtgcca aatattcacc gcctgatgct tcatgagaat atcggactac
    21781 cgcatcgcaa acatcttatc agattatggc gaatgagctg aagattcccc atgtcatagt
    21841 atctttgacc tatatggcag tacaggcaat catcatcgta ggatatcttg attaagttgg
    21901 cttgcctaat ctgtcgactt gtaaatcaat actttataaa cttatctcag aaaacagctt
    21961 cagcgaggct gttttctttg tttgcaggca aatatatcct cacctttgca ttgttgatca
    22021 acaaaacgag attaaaaacc atgttgaatt aaaaatgtaa aaaggagaaa gaaagtatgc
    22081 ctttatttta ttatgcaaga cagtcgtctc tggcgacaaa agagggtgcc aaactttggc
    22141 atctgagttt gaagaaagtg ggaagagccg tggatgcaca acaattggct gaggtgattg
    22201 ccgagaagtc ttccctgact ccgggtgacg tacataatgt aatccgtaac ctgatgacgg
    22261 taatgaggag ccagttgctg aacagccgta cggtgcgtct ggatggcttg ggcacattca
    22321 ccatgaaggc ccgtacgcga ggtaagggag tggtcaaatc tgaagacgtg aatcccaatc
    22381 aggtgactgc tttacgttgc cagtttactc cggaatacac gcgcccggct gccatcggca
    22441 ctacgcgtgc cctgctccaa ggggtggagt ttgagaaatg gacgggagtg gttacggacg
    22501 gtaaggatga tgccggtgat ggtggtaatt ccggtggcgg ttccgacggt gaccagggag
    22561 agaacccgtt aggataagat gtatttacta attttgaaag attaaaacta tgaaaaagaa
    22621 cgtttgggac aaaattttga aggtagtgat agctgttgct tccgccatat tgggagcttt
    22681 aggcgccaat gcaatgaatg tataaattgt agatttatat agaatattag gagaaaggcg
    22741 gtgaagggaa agcact
//
