LOCUS       gnlProkkaANPCGLLL_7    14314 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|ANPCGLLL_7.
ACCESSION   gnlProkkaANPCGLLL_7
VERSION     gnlProkkaANPCGLLL_7
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-11-17 13:18:48
            Original ID  :: gnl|Prokka|ANPCGLLL_7
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 6000187
            Orig. end    :: 6014501
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14314
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:9314]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..9314
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..14314
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14314
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="2"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(208..852)
                     /locus_tag="ctg6_6306"
                     /transl_table=11
                     /translation="MLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTGMAGQREL
                     DNALDVITRYHSNIAILHCVSQYPTHPNNLNLRTITYLKKHYNKFEIGFSDHTIGISAA
                     TAAVAMGAEIIEKHVTIDRHMKGTDQLGSLGPDGVNRMIRDIRIAECWLGTEDLYIEKG
                     VEKSKIKLERSIATRKYIPAGSIIQESDIHLLSLGDGYKWIDKKKCNWSFC"
     CDS             complement(845..1201)
                     /locus_tag="ctg6_6307"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKRDLSEELAVSQMNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLD
                     FIETLCAQRMSVFA"
     CDS             complement(1418..1603)
                     /locus_tag="ctg6_6308"
                     /transl_table=11
                     /translation="MKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLL
                     YREHVTNYIYSHPELF"
     CDS             complement(1731..1952)
                     /locus_tag="ctg6_6309"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKVLQR"
     CDS             complement(2124..2879)
                     /locus_tag="ctg6_6310"
                     /transl_table=11
                     /translation="MPFFCFCRASKCFTATFYYDFSFKKRSQQIICLGYYTPFKDDYHM
                     GDHSYDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCN
                     VIKREISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAA
                     LILKLHPLQNKTVLKKDLPKGILVFEQTYKYGLYDLLSFSDGMITDYTSTYFDFLLVNK
                     PVIFNFYDIEEYRRVRGFSFEPIEFFLCR"
     CDS             complement(2961..3221)
                     /locus_tag="ctg6_6311"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKIVLNIIKYMLKFMILLVFQNIKNIFMA"
     CDS             complement(3938..4621)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg6_6312"
                     /sec_met_domain="Polysacc_synt (E-value: 1e-21, bitscore:
                     76.4, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWSAIERFSLQGVQFIIQIILARLLLPSDYGMIGMLAIFLQVAQV
                     FIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFSASLIADFYNMPTLVLVI
                     RFIALSLIINALSAIHRTKLIISVNFKTQSKISLGAAFISGVIGIWMAYVGCGVWALVW
                     QTLLNSIILTILFYCLVHWKPLHTFSKSSFERLFNFGSKLLISSLINTVYRNLYTIVIG
                     KSFLL"
     CDS             complement(4861..5004)
                     /locus_tag="ctg6_6313"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             complement(5001..6122)
                     /NRPS_PKS="Domain: Aminotran_5 (30-366). E-value: 2.9e-34.
                     Score: 110.4. Matches aSDomain:
                     nrpspksdomains_ctg6_6314_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 76.3; E-value:
                     3.6e-23)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_6314"
                     /sec_met_domain="Aminotran_5 (E-value: 8.4e-29, bitscore:
                     99.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFIIGNEEQIKFSKKYPKR
                     SYYCNLYLQYENFERTGEMHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHS
                     GINEIGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFR
                     ICALGEIEVDDIENFFKVLKAALNHYNVTLPMS"
     aSDomain        complement(5025..6032)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg6_6314_Aminotran_5.1"
                     /evalue="2.90E-34"
                     /label="ctg6_6314_Aminotran_5.1"
                     /locus_tag="ctg6_6314"
                     /protein_end="366"
                     /protein_start="30"
                     /score="110.4"
                     /tool="antismash"
                     /translation="PREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDICL
                     NSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPDI
                     AMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMASA
                     QKGLQAMTGLSFIIGNEEQIKFSKKYPKRSYYCNLYLQYENFERTGEMHFTPPVQTIYA
                     TRQALNEYFEVGEEAKFARHKRVFEAIHSGINEIGLKSVIKREWQSGLVVSVQYPEDPN
                     WDFEKIHDYCYERGFTIYPGKISTEDTFRICALGEIEVDDIENFFKVLKAALNHY"
     CDS             complement(6132..7076)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1055:pyruvate oxidase/decarboxylase (Score: 59;
                     E-value: 6.1e-18)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_6315"
                     /sec_met_domain="TPP_enzyme_C (E-value: 3.4e-18, bitscore:
                     64.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRGE
                     PGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAIII
                     RKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKEQ
                     GHEHDFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGAISNIGDLSPKNYY
                     HILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIEEAMKQLPKLCGPV
                     LLEIKVKIDSRENLGRPTTTPIENKEHFMDFLK"
     CDS             complement(7273..8574)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: CTP_transf_like"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 208.9;
                     E-value: 1.5e-63)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_6316"
                     /sec_met_domain="CTP_transf_like (E-value: 1.1e-10,
                     bitscore: 40.6, seeds: 65, tool: rule-based-clusters)"
                     /sec_met_domain="phosphonates (E-value: 1.1e-118, bitscore:
                     394.2, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 1.3e-60, bitscore:
                     203.6, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSKTVYIGMTADIMHPGLIRIINEATKYGDVIIGLLTDKAIAEHK
                     RLPYLTYEQRKEVVQNIKGVCKVVPQEEWSYVENLKRIKPDYIIHGDDWKTGPLREERV
                     RVFEVMNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLINAKPVVRILE
                     AHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTTRLQDLNNIL
                     ECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFGTDVIQTQDT
                     IEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGADGIMIHSKN
                     KSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANHMLRAAYPAM
                     MNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             complement(8595..9314)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 54.5; E-value:
                     1.6e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_6317"
                     /sec_met_domain="NTP_transf_3 (E-value: 8.9e-14, bitscore:
                     50.8, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASIVDEQPNLGYEYELLRISCSQSPVYVHKVEGLKWYEI
                     DDISDLEYAEKYIVPYC"
     CDS             complement(9548..9778)
                     /locus_tag="ctg6_6318"
                     /transl_table=11
                     /translation="MERLFKERQQEYYAAQRKYADYVDAHDNVVLQSVRAEQERLQNDM
                     SLAYQIYSQVANQLQVSRAKVQEEKASLCSS"
     CDS             complement(9837..10130)
                     /locus_tag="ctg6_6319"
                     /transl_table=11
                     /translation="MTLGSYLDEESSPWWDYLIGFPGIVIGGVKSLFGEDTVPASGGRQ
                     GTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQKSADHCGYSRFCRS"
     CDS             complement(10135..10317)
                     /locus_tag="ctg6_6320"
                     /transl_table=11
                     /translation="MGNAKGSNGLAGLAASFLGDGALIGESTDALNASLSADIVSSTPF
                     LLELLEMEVSVSKKG"
     CDS             complement(10319..10531)
                     /locus_tag="ctg6_6321"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKGYPFS"
     CDS             complement(10542..12911)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 32.3;
                     E-value: 6.8e-10)"
                     /gene_kind="transport"
                     /locus_tag="ctg6_6322"
                     /sec_met_domain="Poly_export (E-value: 1.4e-15, bitscore:
                     55.7, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGSGSLMAQSMSDSQVLEYVKDGIRQGKEQKQLASELARKGVTK
                     EQAMRVKQLYEQQNNVNTSKSTGTDINESRLREETKKNTSDMLEDHPTTQDLARGDQVF
                     GRNIFNTRNLTFEPSVNLATPANYRLGPGDEVIIDIWGASQNTIRQQISPEGTINIQKI
                     GPVNLSGMTVSAANDYLKGALNKIYNGLNNTTDPTSDIRLTLGNIRTIQINVMGEVVQP
                     GTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVYEFIMKGNTQDDIRL
                     QEGDVVIVPAYDVLVKISGKVKRPMRFEMKKDENLATLIKYAGGFEADAYTRSLRVVRQ
                     NGEEYEVNTVKDMDYSIYTMRNGDVVTAEAILNRFTNKLEIRGAVYRPGIYQLSGKLNT
                     IRELVHEAQGLTGDAFLNRAVLYRQREDLTSEVVQIDIKSIMDGTSPNLALMKNDILYI
                     PSIHDLEDRGNVTVHGEVAHPDSYPYADNMTLEDLIIQAGGLKEAASTVRIDVSRRIKN
                     PRSIADNDTIGQMYTFSLKDGFVIDGQPGFILQPYDEVYVRRSPGYQAQQNVAIEGEIL
                     FGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKKRMGDVIRLMSRQLG
                     EAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIPKNTNTVTINGAVMV
                     PNTVSYMKGKNVDYYLNQAGGCSDNARKSKKFIVYMNGQVTKVKGSGKKQIEPGCEIIV
                     PGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             complement(13349..13927)
                     /locus_tag="ctg6_6323"
                     /transl_table=11
                     /translation="MILRKKKSLNAGPINGTGEGVAHSKRWYVALVRMHHEKKVSEHLD
                     KMGIENFVPVQQEFHQWSDRRKLVTSVLLPMMVFVHVDPKERMEVLSFSTVSRYMVMRG
                     ESSPAVIPDEQMARFRFMLDYSEESISMNSSPLARGEKVRVIKGPLTGLVGELVNVDGK
                     SKIAVRLNMLGCACVDMPVGYVEPIMAAV"
ORIGIN
        1 ataaaacatt ccgccatcag tccaaacgcc atcaatatct gtaagtataa gctttatctc
       61 tttcattttt ttagtatttt acccttattt attaatcact acttagctta tagcaggcag
      121 tactctatac cgtaatacaa gttgcagtag gaatatatct attcaataaa atcaggatat
      181 attatttcat tcgctgatat atcttgttta gcaaaatgac caattacatt tttttttatc
      241 tatccattta taaccatcac caagactcag taaatgaatg tccgactctt gaataatact
      301 acctgctgga atatattttc gagtggcaat agaacgttca agttttatct tagacttctc
      361 cacccctttt tctatataaa gatcttcagt accaagccaa cactctgcta tgcgaatatc
      421 tcgaatcata cgattaaccc catctggacc taaagagcca agctggtctg ttcctttcat
      481 atgccgatca attgttacat gcttttctat aatttccgct cccatcgcta cagcagctgt
      541 agcagcagaa atacctattg tatgatcaga aaaacctatc tcaaacttat tgtaatgctt
      601 cttcaaatat gttattgtac gtagattcaa attatttgga tgagttggat actgagatac
      661 acaatgtaga atagctatat tactatgata tctcgttatc acatctaatg cattgtcaag
      721 ttctctttga ccagccattc ctgtcgataa tataatagga atatgagttt ctgctaatgc
      781 ttcaagcaat ggtaagttag tcaaatcacg actagcaact tttagcctat ccggtgtgaa
      841 cagtttaagc aaagacagac atcctttgtg cacataacgt ctcgataaaa tctaatccta
      901 atgacttagc atatttataa atctcaaaat gcgcttgatc atcaagctca agaaaagcac
      961 gatgttcacc ataagtacgc ccaaaagaat taggattgtc atatatttga ttcatttgag
     1021 aaacagccaa ttcttctgat aaatctcttt tagtcatttt aacagcattc attggcatga
     1081 aatccatacc aaaaacatcc tcatgtacag gtcgtgagat taattcaata atcaacttag
     1141 ccaagtcaac agaaccatta tgattctgcc ctatttcacc aataatataa gtattcttca
     1201 ttatttagaa ttttttttta tttgttgttt catcagttga atgtattctg catgtcttcg
     1261 aacatagtct acaatcactt ctatcgatat ttccactctt ttttcttgta aatccctata
     1321 tattctctgt gctacagaaa aatcttctaa cgtatcaatc gtgagtcgaa tattatgatg
     1381 ttttgacacg actggagatc ctgaaatcca ttgaatatta aaaaagttca ggatgactat
     1441 atatataatt agtaacatgt tcacgataca ataaatcatc agtaaatcct ataactcgct
     1501 tcagcgcatc aagcgttaca aattctcccc aaaaaccgaa atgagtttta attgatggag
     1561 taccatcaat atcaaaactt atataatcgt tacaagattt cattgctatt tcgaccaatt
     1621 gccttgccgc atgtacatct aaaaatggat tatcagaaca tattcggaat ataccctgta
     1681 tatcaaaata ttcagcaaca tcaatgaatc gttttaaaac atcattctcc tcacctctga
     1741 agcactttta cccctaatgc aagtgccttc ttttcaatag gttcattgat aacagaattt
     1801 gttgtagcaa taattactgg aatattcgat atagcagaaa gcttatgaac cattaagtca
     1861 agaatcgatt gattaccata gaaaggtttc aatatttttc caggcaaacg tgtagaacct
     1921 aaacgtgcct gcaccacaaa tgcataattc attttattta ttatatttca tttaaaaata
     1981 tgtcacatat tctctttgtt gaattatcat cttgaaattg attcatcaat aaagaaatat
     2041 gacgtcgatg ttcagcatga atatctttcc cagccagaag tcccatcaca gcatctatca
     2101 attcattata attgtaaaca atatcacctg cacaaaaaaa attctattgg ctcaaatgag
     2161 aaacctctta ctctacgata ttcttcaata tcgtagaaat taaatatgac tggcttattt
     2221 accaataaaa aatcaaaata ggtagaagta taatcagtaa tcattccatc tgaaaatgac
     2281 aaaagatcat acaatccata tttatatgtt tgttcaaaaa caagtatacc tttgggtaaa
     2341 tcttttttta agactgtttt attctgcaaa ggatgtaatt taagaattaa agccgcatta
     2401 aacttcaata gtattttcga taacttcaac aaatcacaat caacatatcc gagtattgaa
     2461 cgcaaattac cttcagtaac agtctcataa tcacgaaaag ttggagtata aactatatat
     2521 ttagttacat catatcccgc aaatttcgaa atttctcttt taataacatt gcaattattt
     2581 ttcgatatca acaaatcatt tctgggaaat cctaagactt tgaatttatc atatgagatt
     2641 ccacaatcta ttgaaattat tctagcactt aaacaagaag tagcaataga gtaatcaaat
     2701 gagttacatg ttgtattacg aaatttatca taagaatgat ctcccatatg ataatcatct
     2761 ttgaatggag tataataccc caaacaaata atctgttgag agcgtttttt aaatgaaaaa
     2821 tcataataaa aagtagctgt aaaacattta cttgctctac aaaaacaaaa aaaaggcata
     2881 caacatatcc ttaaaagata ctttattaaa gaaaaaacgt ccaacacatg cacataaaaa
     2941 agtacaccta atattaggat ttatgccata aatatattct tgatattctg aaatacgaga
     3001 agaatcataa atttcaacat atattttata atattcagca ctatcttttt tagcaaataa
     3061 tttaacagaa cgagaacatt atctgacgaa taatttataa tatcatattt atctgttcta
     3121 caattaggat gaggaataaa atacaatgat ctactatcaa ctggcacaca atggttaatt
     3181 atctttacta ttacttgaaa aatctttttt aatattttca tctatgtttt tagttttaat
     3241 gatcaatgtt aaaatacaaa aaaaagaatc tagcttaaaa agaaaagaaa gtaaaatata
     3301 gaaggacatc ccagtaatac atccaatcac aatttttact atatcagttt caaagaaaga
     3361 aatacatata aaaacgatcc ccccattatg aaagagagta ttaaacttgg aaatacatct
     3421 ttaacttgca actttaaggt caaatcaata agagaattag tataatatgt attcaaatat
     3481 gtcgctatca gagagtaaat aactctaccc caacacatca cctcaagccc aaatggaatt
     3541 gacacaaaaa gaatgaatat agcaatcgtc tttttattat ttcaagacgt aacgacagat
     3601 cagatcttcc tttaacccat aataaattca aattaatttg gctcaaatga tcaaacatcc
     3661 aatccaaaca taatatctgt aaaaagaata acaaccccag accatttatc tgttaacaat
     3721 agactaataa taggattagc caaaacaagt aaacctacca ttaaaggaaa aattatatat
     3781 gaggataatc tgatataatt tcgatatgcg tttgttaaac atttatcatc atcttgaatg
     3841 gaacttaaaa taggatacgc tactctagaa actaaagcat ttaaattatt ggaaggaaaa
     3901 atagcaaatt gttctgctct tgtatagtaa ccaagctcta caacagaaaa ctttttccta
     3961 ttacaatggt atacagatta cgatatactg tattgataag acttgagatc aataatttag
     4021 atccgaaatt gaataatctt tcaaaagaac ttttggagaa agtatgtaaa ggtttccaat
     4081 gaactaaaca gtaaaacaaa attgtcaaaa ttatactatt taagagagtt tgccaaacta
     4141 aagcccaaac cccgcaaccg acataagcca tccatattcc aatcacgcct gatataaaag
     4201 ctgcacctaa tgaaatttta gattgagttt taaagtttac agaaataatt aatttcgttc
     4261 tgtgaatagc cgataaagca tttattatca acgacaatgc tataaaacga attacaagaa
     4321 ctaaagtcgg catattataa aagtctgcaa tcaaagaagc cgaaaaaaac aatataccat
     4381 agaataatac tgcgacaaga atattaaaat aaaagacagt ggcaaaatcc tcttcagttc
     4441 tatctttttt ctggattaaa gcatttgtaa aaccgctatc tataaatact tgagcgactt
     4501 gaagaaaaat agctaacatc ccgatcatac cataatccga tggtagtaac aaacgagcta
     4561 atattatttg aattataaac tgtactcctt gtaaagagaa acgttctata gcgctccaca
     4621 ttattcctga tacagttttc tgctttagat tttccattac ttaaatacag tataaaaaca
     4681 actacattta ccgatatcaa ttatattttt ccaatattct cactaattgg ttattatctt
     4741 cttcgcccct taccgcaatt ctaatatggt ctctcccact aaaaagcaaa ttaccctaca
     4801 caaacattat ctcctataac taccgatgcc tttttataag aataaagaac tcctaatgca
     4861 tcacctcaaa ttaatattgc catatttgcc tactaagcga aagctacgaa taggcactcc
     4921 agaaataaca ctttccggat ggaagtgtat accacgaagg gaaaaataaa aatgacgaat
     4981 cttcaataat atttctgcaa tcatgacatc ggtaatgtga cgttataatg atttaatgca
     5041 gcttttagta ctttaaagaa gttctcaata tcatctactt ctatctctcc taaagcacag
     5101 attctaaaag tatcctcagt tgatatctta cctggataaa tcgtaaatcc acgctcataa
     5161 caataatcat gtattttctc aaaatcccag ttgggatctt ctgggtattg aactgagaca
     5221 accagtcctg actgccattc acgctttatt acacttttaa gaccaatttc atttatacct
     5281 gaatgaatag cctcaaaaac tcttttgtga cgggcaaact tagcttcttc acccacttca
     5341 aaatattcat ttaatgcctg acgagtggcg taaatagttt gtaccggtgg agtaaaatgc
     5401 atttcacctg ttctctcaaa attctcatac tgcaaataaa gattacaata gtaagaacgc
     5461 ttgggatatt tttttgaaaa cttaatctgt tcctcattgc ctataataaa agaaagacct
     5521 gtcatcgctt gaagtccttt ttgagcagat gccatacaaa aatccacatt atctttctct
     5581 atatcaaaag gaatcatgcc caaagaagaa gtagtatcga cgacaaattt agcctgatat
     5641 ttatgagcta tagcgcccat ctcgcgaata gggttcagaa ttcctgtacc cgtctcgtga
     5701 tgagtagtat aaaccatagc tatatcagga ttttcttgca acacattttc caccaccgat
     5761 aaatcaggac gttcgtaaac ggaaaattcc aaattaatat gaggcaaacc ataatattga
     5821 cacacttcta cagcacgggt actatatgcc ccattattca ctataagcac ccttttgtct
     5881 tcaggaagaa gagaatttag acatatatca atattgatgg ttcctgagcc acaaaataat
     5941 acagcggtat gtttttccaa attcccatga gcaactctga ccaaatcgtc ccgaagttgt
     6001 ttcatcatac ctgcgaattc tttctcgcga ggacaaatat ccggaacaac ttgtgccatt
     6061 tttacactgt cagtagtagt ggcaggccca ggatttaata atatttttct ttctattttc
     6121 atcgaatata tttattttaa aaaatccata aaatgctcct tattctctat aggagtagtc
     6181 gtgggacgtc ccaaattctc ccgagaatct attttaacct ttatttccaa caaaacagga
     6241 ccacataact ttggaagctg cttcattgct tcttcaattt caacttttgt acaaacagta
     6301 taagtatgct tatatccgct cccccggaca atagccggaa tatctaaact aaatcctaaa
     6361 gtaggctgtc ctcctacaga ctcgtgagca ccattgttaa acaaaatatg ataatagttt
     6421 ttaggagata aatcgccaat gttactaatt gcccctaaat gcataataaa tgctccatca
     6481 ccatccaagc aataaacagg tctatcttgc tttgctatag caatacccaa agagattgat
     6541 gaactatgtc ccatagagcc taccgtgaga aaatcatgtt catgaccttg ctctttcatt
     6601 tctcgatatt caaataactc acgagaaagc ttgccagtag tagaaacgac cactgaattt
     6661 tcaggcagat aatccacaac tatttgcaaa gcatcctcac gagataaagg ataattacat
     6721 ccgaactctt tttgaagttt atatttgcca aaaacatctt tccgaataat tattgcatga
     6781 ggaatattct tagtttttgc tgattgtatg atatcatgga gctgaataaa tgcatcattc
     6841 tcatttgaat caagaattat ataaggaatc cgcattgctt tcaacaaatc taaagttacc
     6901 tcaccctgtt ttttatgctg aggttcatct tttgttcccg gttcaccacg ccagccaatc
     6961 atcaaaagca ttggaaaact gtatacttgt tcatctgcaa gagacagcag aggattaaca
     7021 gtattaccca agccggaatt ttgcatataa accacaggaa ccttacctga tgccatataa
     7081 taacctgaag caattcctac agccgcacct tcattagcag ctatgatatg tttctcacgt
     7141 gaagtatggt ctgtgatata ggcacaaata ttttttagta atgagtctgg aactcctgta
     7201 aaaaatcaac gtcatgactc agaaacgttt cataaacttt ttctacgctt aacataatga
     7261 tattcctctt ttttatttag tacctggaat cagttccaat atttctttta tgggcataca
     7321 cagttcgcgc acctctaaag cacgttcatt ctctaatatt atctttgcga cattcatcat
     7381 agcaggataa gcggcacgaa gcatatgatt agcataaata attatattca caccccaatc
     7441 acacaattca gactcataaa tatgatcata tgtagtaggc acaaccacga taggtacatg
     7501 agcatactgt tttcgaaacg ccaaacaaaa ttcttttata tcttcacccg acttattttt
     7561 gctatgtatc ataataccgt ccgctcccgc ttggacatat gcaaaagctc tctctaaagc
     7621 atcacttacc ggctttcccg ctataaggct ctcaatacga gcgataatca taaaatcatc
     7681 agtaatctga gatgcctttc ctgctttgat cttattacag aaaccttcga ttgtatcttg
     7741 agtttgaata acatctgtac caaacaatga attctttttt aatccaactt tatcttcaat
     7801 tattatagct gaaattccat gacgttctaa agtgcgtact gtaaatacga aatgttcaat
     7861 tttaccacct gtatctccat caaaaataat aggtttagta gtacactcca gaatattatt
     7921 caaatcttgc aatcgggtag ttaaatcaac cgcctcaata tcaggtttac ctttactggt
     7981 tgaatccgta aggctactag accacattcc gtcaaatact tccctcttat ccccttttaa
     8041 tatttcctga ttttcaatta tcaagccaca tagtccatca tgagcttcca aaatacgaac
     8101 tacgggtttg gcatttatca aacgacgaag tgattttaaa cgtacatcag gggttgtacc
     8161 tatagcctta atatctttat ccaaagaaga tgaattaatt cccaaagtat atggaatttc
     8221 gataaccttt cctccctgtt cattcatcac ttcaaatacg cgcacacgtt cttcacgtaa
     8281 aggcccggtt ttccagtcgt caccatgaat tatatagtca ggtttaatgc gtttgagatt
     8341 ctcaacatag ctccattctt cttgaggaac aactttacat acgcctttaa tattctgaac
     8401 tacctctttt cgttgttcat aggtcagata aggaaggcgt ttatgctccg caatagcttt
     8461 atctgtaaga agaccaatta taacatcacc gtatttagta gcctcattaa taatgcggat
     8521 aagtcctgga tgcataatat ccgcagtcat cccaatataa actgtcttac tcataatttg
     8581 atatattatt ttaattaaca atacggaaca atatatttct ctgcatattc caaatctgat
     8641 atgtcatcga tttcatacca tttcagccct tctactttat gcacataaac aggagattga
     8701 gaacaagata ttcgtagtaa ttcatactca tatcccaaat tgggttgttc atcaacaata
     8761 ctcgcataat cagcacacat tattttgtaa aaggaaccgg atagtttatg gatgccgacc
     8821 aattcgcctt tagcgtttag tttattctta ttgacagaac atgaagaaag gcgaaaatta
     8881 tcatcatgtt ccacataata ctgatcttga aactttgtca ctggagttat tagcattgca
     8941 tctgccgcag gacactccaa taagctcatt attgcttgtt tctcaaaaat caaatctgac
     9001 tctaacaata aaaaatcatc attgcccaga atctcccgcg tattatataa agtatacata
     9061 ctatttgttt cagcataacg aggactaaaa caggtttcaa gcataggata gtctgtcttc
     9121 aattcttcat aaacttcttg tttatatcct gtaccgatta caattcgctc aatgtcacat
     9181 gataacaaag tatcaataga acgaactatc attggaatac ctcccacttt gacgaaccct
     9241 ttaggtatca attctgtata ttggccaaaa cgggttccca tgcccgcagc cattatcata
     9301 gctgtacgta tcattcgttt aataatatag taagtgaatt taattgatgt aagaatgttg
     9361 taaacgacgt tttagcatca tttatcctgt tctatctcct tatttttcag ttcttttctc
     9421 aagctagcca gcagactttt gccaaaaaaa cacccacacg agagtaccag atacggacag
     9481 gaacacaaat aataaaatat aaattttgag tcccatacct gaaggtttca aaggtacaac
     9541 ggcaggctca actactgcaa agactggctt tttcctcctg tactttggct ctggatacct
     9601 gcaactgatt agcaacctga ctatatatct gataagccaa actcatgtcg ttctgtaaac
     9661 gctcctgctc agcacgtaca ctttgaagaa ccacattatc atgggcgtct acataatccg
     9721 catattttct ttgagcagca taatattcct gctgacgttc tttaaacaac cgttccaaat
     9781 acgcacagtc ttcttttact tttgaagttc gatacccaat aatatattcc tgtaatttat
     9841 gaacgacaga atctgctata accgcagtga tctgcggatt tttgtaaggt gaccgtaatg
     9901 ctcgttatgg cggttttctt atcaatggat gcactaatct tctttttaag aaaattaatc
     9961 ttctcattta cttctttcgt caattcgata gttccttgcc gccctccact ggcaggaacc
    10021 gtatcttctc cgaataatga tttaactcct cctattacta tgcccggaaa acctataaga
    10081 taatcccacc aaggagatga ctcttcatcg agataagacc ccaaagtcat tttatcatcc
    10141 ttttttagaa acggagactt ccatttctaa aagttccaat aaaaaaggag ttgaagaaac
    10201 aatatctgct gaaagagaag cgttcaaggc atctgtgctt tcccctatta gagccccatc
    10261 tcccaaaaac gaggcagcaa gtccggctaa accattactt cccttcgcat tacccatttc
    10321 aggagaaagg gtaacctttt actgtatatt gcttgggaat gctcaatgcc accactatag
    10381 caattattac tcccactcca gcagctttgc atagtactcc acgaacagta ataatcttat
    10441 aaaaaatagc catcaagtct atttccattt catcatcttt ccttttatcc acttcagaaa
    10501 acggttcttg ataagattgc ttttcaatca taataggtca tttatttctt tatcaaatta
    10561 gcaatagaag caatcatcat tcccaaagaa ctgaaggaag tagcataacc taaaatatta
    10621 gctatgttcc ctttcttctt agccttacca ggcacaataa tctcacaccc cggctcaatc
    10681 tgtttcttac cactaccctt aaccttcgtc acctgaccat tcatgtaaac aatgaacttc
    10741 ttactcttcc ttgcattatc agaacagcca ccggcctgat tcaggtaata atccacattc
    10801 tttcccttca tataagaaac cgtattcgga accatgacag caccattgat agttacagta
    10861 ttagtattct taggtatgga gatcacatca ccttcacgta agacaagatc ggcattactt
    10921 ttaggattgc tcaaggcttt ttccaaatct attccaaccg taaaagtatc ttcaacacga
    10981 atacccaaag agtcaatcat ggcttcgccc aattgcctgc tcataaggcg aattacatca
    11041 cccatacgtt tcttttcact agcgttagcc acacgggtca gtttcgcacc acgcagatag
    11101 gcataattgg tcggaccgcc ggctttattc actaaatcgg aaagacgttc ctcacggctg
    11161 gtcatggcgt aatttcctcc gaaaaggatt tcaccttcaa tggctacatt ctgttgtgcc
    11221 tgatagcccg gactgcgacg gacataaact tcgtcataag gctgaaggat aaaaccgggc
    11281 tgaccgtcga tgacaaaacc atcctttaaa gagaaggtat acatctgacc gatagtatca
    11341 ttatccgcga tactacgggg attcttgatt cgtctcgaca catcaatgcg gacagtagaa
    11401 gcagcttctt tcaagccacc ggcctggatg atcaggtcct caagtgtcat gttatcagca
    11461 tagggatagg aatcagggtg cgcgacttca ccgtgaactg tgacattgcc acgatcttcc
    11521 agatcgtgaa tgctcggaat gtaaaggatg tcattcttca tcagggcaag gttcggggaa
    11581 gtaccgtcca tgatagactt gatgtctatc tgaacaactt cactggtcaa atcctcacgc
    11641 tggcgataaa ggacggcacg attcaggaaa gcgtcaccgg tcagaccctg agcttcatgg
    11701 acaagttcgc ggatcgtgtt cagtttaccg ctgagctggt agataccggg acgatagaca
    11761 gcgccacgga tttccagttt gtttgtgaag cggttaagga tggcttcggc tgttacaacg
    11821 tcaccgttac gcattgtgta gatgctgtag tccatatcct tgaccgtgtt gacctcatat
    11881 tcctcaccat tctgacggac aacacgcaat gaacgggtgt aggcatcggc ttcaaagccg
    11941 ccggcatatt tgattaaagt ggcaaggttc tcgtctttct tcatttcgaa acgcataggg
    12001 cgttttacct tgccgctgat ctttaccaag acatcgtagg cggggacgat aaccacgtca
    12061 ccttcctgaa ggcggatgtc atcctgtgtg ttgcctttca tgataaattc gtagacgtcg
    12121 atggtggcga tattctttcc gttgcgtacc aactgaacgt ttcggaggct gccgatatca
    12181 ctcacgccgc ctgcacggta aagcgcgtgg aagacggtag agaaggaaga aagggcgtag
    12241 gtacccggct gcacgacctc tcccatcaca ttgatctgaa tagtacggat attacctaac
    12301 gtcagacgaa tgtcggaagt agggtcggta gtattgttca gaccgttata gatcttattc
    12361 agggcgccct tcagatagtc gttggcggcg gagactgtca taccgctaag gttgacagga
    12421 ccgatcttct gaatattgat ggtgccttca ggagagatct gctggcggat cgtgttctgg
    12481 ctagcacccc agatatcgat gatgacttca tcaccgggac ccagacggta attggcagga
    12541 gtggcaaggt tgacactagg ctcgaacgtc aggttgcggg tattgaagat gttacgtccg
    12601 aagacctgat caccacgggc aaggtcctga gtagtcggat gatcctccag catatcggaa
    12661 gtattcttct tagtctcttc acgcaggcgg gattcgttga tgtccgtgcc cgttgatttc
    12721 gaggtattta cattgttctg ctgctcgtat agctgcttca cacgcattgc ctgttctttg
    12781 gttacaccct tacgggctag ttcggaagca agctgcttct gttccttgcc ttggcggatg
    12841 ccgtctttta catattccag tacctgtgag tcactcatgg actgagccat aagcgagcca
    12901 cttcccagca tcaaacaaaa tagtagaatg ctaaaaagtc gttgtatttt cattgacaaa
    12961 taaaaaagtt tcagttgatt tcacacagtt cctgcatccc atgacagacg gcagataact
    13021 gttgcttaag aagagaaggg ggaagaacat cgagaagaga cagagaacgg gtcaaaacag
    13081 cctgttttct ttcttcgtct tccggattgg cgtacatcga cacattatat ccctgaagga
    13141 tggccaaaca cagggtagca tcctgctccg gtgtctcccc cgttgagaat ataaatcgtt
    13201 aatcttttcg tggatggatc gttgtaatgc tgaaagatca tccaaataca cgcagcctgc
    13261 actcccccca ccaggaagca gcatacgtac caaacttaat aaaccctcta tattttcttg
    13321 taaaataata gcatccatat cccttgcctt aaacagccgc cataatcggc tctacataac
    13381 cgacaggcat atcaacacag gcgcatccca gcatattcaa gcgaacagca atcttacttt
    13441 taccatccac attgaccagt tcgccaacaa gacccgtcaa cggacctttg atcacgcgaa
    13501 ccttttcgcc acgagccaaa ggagaactgt tcatgcttat cgattcttcc gaataatcaa
    13561 gcatgaaacg gaaacgagcc atctgctcgt caggaattac agcaggacta ctctcgccgc
    13621 gcatcaccat gtaacggctg acagtagaaa aactcaggac ttccatgcgt tccttagggt
    13681 caacgtgtac gaagaccatc ataggaagca agacggaggt gaccagcttg cgacggtcgc
    13741 tccattggtg gaattcctgt tgaacgggaa cgaaattctc gatacccatc ttgtccagat
    13801 gctcggaaac cttcttttca tggtgcatcc gaaccaaagc aacataccag cgttttgagt
    13861 gtgctacgcc ttcccctgtc ccattaatag gcccagcatt tagtgatttc ttttttctta
    13921 aaatcatatt tttttacccc atgtttatcc gttacttctt aggtaacgaa caagcatagg
    13981 gcaagcagaa aagggaactt ttttcaacga aaacatcaga agaggactgg tattcaggaa
    14041 ataaagcaga agtgaaggtg tttttcatga attggaataa aaaaaagaca taacacggat
    14101 attgtcattt tccgcctgtt atgcctgcat ttgattcatt ttccgaaatt aatttcattt
    14161 ttgtttgcgt attttcataa atatgtccat ctttgcgcca tgaatcattc cgttacctaa
    14221 gaagtaacgc acaccgataa acactgtata tcaagcttct aaatcagata cactgaccta
    14281 ctccgcaccg ctttacgtaa gacaaattca tccg
//
