LOCUS       c00003_gnlPro..        24552 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|APBMDKCP_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 11:18:01
            Original ID  :: gnl|Prokka|APBMDKCP_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 222971
            Orig. end    :: 247523
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24552
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[232971:237523]"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14552
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /neighbourhood="10000"
                     /product="succinate2propionate"
                     /protocluster_number="1"
     cand_cluster    1..24552
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(minimum(4, [AcetylCoA_hyd_C,
                     AcetylCoA_hydro, B12-binding, Biotin_lipoyl, Glyoxalase_4,
                     HMGL-like, MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma,
                     PYC_OADA]) and minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /kind="single"
                     /product="succinate2propionate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24552
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="succinate2propionate"
                     /region_number="1"
                     /rules="(minimum(4, [AcetylCoA_hyd_C, AcetylCoA_hydro,
                     B12-binding, Biotin_lipoyl, Glyoxalase_4, HMGL-like,
                     MM_CoA_mutase, MeaB, OAD_beta, OAD_gamma, PYC_OADA]) and
                     minimum(1, [CT_Btheta, CT_Propionyl_CoA1,
                     CT_Propionyl_CoA2, CT_Propionyl_CoA3, CT_Vparvula]) and not
                     Cytidylate_kin)"
                     /tool="gutsmash"
     CDS             complement(39..317)
                     /locus_tag="ctg3_213"
                     /transl_table=11
                     /translation="MGSAVKIHDYRAFRDKYGLTDDEILYMGDDVPDIEVMCECGLPCC
                     PKDAVPEVKSVAKYISYADGGRGCGRDVVEQVLKAHGLWMVEDAFGW"
     CDS             complement(389..559)
                     /locus_tag="ctg3_214"
                     /transl_table=11
                     /translation="MSTINYDLSRIKALAFDVDGVLSSTTVPLHPSGEPMRTVNIKDGY
                     AIQLAVKKDFT"
     CDS             complement(540..1334)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) F420_oxidored"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_215"
                     /sec_met_domain="F420_oxidored (E-value: 1.4e-11, bitscore:
                     43.4, seeds: 48, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRSIEDTPIVFIGAGNLATNLAKALYRKGFRIVQVYSRTMESAR
                     TLAEKVEAEYTTDLQAVSKDAKLYIVSLKDDALVDLLPQITEGKQASLLVHTAGSIPMS
                     VWEGHAERYGVFYPMQTFSKQREVKFQEVPFFVEAKRPEDVELLKAVAATLSEKVYEAS
                     SEQRKSLHLAAVFICNFTNHMYALAADLLEKYNLPFDVMLPLIDETARKVHELAPRDAQ
                     TRPAVRYDENVMSNHLAMLVDSPALQEIYKLMSKSIHEHHQL"
     CDS             complement(1342..1677)
                     /locus_tag="ctg3_216"
                     /transl_table=11
                     /translation="MGAAKANNSKDTYLATAVTFIVIGALYLIDKLIHFSSIGLPWVMN
                     KDNMLLYASICFLIFKRDKSIGFVLLGLWLVMNIGLVMSLLGSLSGYLLPLTLLIIGIV
                     LFWFAKR"
     CDS             complement(1680..2216)
                     /locus_tag="ctg3_217"
                     /transl_table=11
                     /translation="MENFSELIKNRRSMRKFTDEELTQDQVVALMKAALMSPSSKRSNS
                     WQFVVVDDKEVLKELSHCKEQASSFIADAALAIVVMADPLASDVWIEDASIASIMIQLQ
                     AEDLGLGSCWVQVRERFTATGMPSDEFVHGILDIPLQLQILSVIAIGHKGMERKPFNEE
                     HLQWEKIHINKFGGK"
     CDS             2339..2563
                     /locus_tag="ctg3_218"
                     /transl_table=11
                     /translation="MKKRITQDDYVKANRKASREAEIEMYGHPICHKRVHQSKKVYNRR
                     KIKAADKKLPYFFVFKIASLSSRHSDTIQ"
     CDS             complement(2652..3194)
                     /locus_tag="ctg3_219"
                     /transl_table=11
                     /translation="MLEEILAYNKQFVENKGYESYITNKYPDKKIAILSCMDTRLTALL
                     PAALGIKNGDVKMIKNAGGVISHPFGSVIRSLLVAIFELGVEEIMVIAHSDCGACHMHS
                     EVMLEKMKARGINPDYIDMMRFCGVDFHSWLDGFEDTEKSVRGTVDFIVRHPLIPSDVT
                     VYGFIIDSTTGELTRIV"
     CDS             complement(3301..5325)
                     /locus_tag="ctg3_220"
                     /transl_table=11
                     /translation="MKSTIYKIAALTFAVASMSACSLDEYNPSQKTGDEILATFDGLKG
                     LQSYCYSSLYGQLFSVYDFLSVAEGGTDCWITPAGNPDYAKQVIYYDGLATNTNATNKL
                     FGQAYSMIGNCNAVVNRAELLTDGNEKDITTLVAEARCLRAFYYSILVNTYGNVTLTLE
                     ESSQDPILTPQRNSIEELYTQIIDDLKFAANNLEDTPYDSNRARVTKKTALGLLARVYA
                     QGGGEYGLTEDGVSYWQRAKEVAEDMILAYGDCLYDDVEDVWAPANNRNNKEALFIAAG
                     PDATNLENWNAGTQCNNNFTYMYPKPNTLTIYPTPDNQNYWYGRTNNNTLAPSKYLLDC
                     FDADYDKRWEVTFTTAFVQFSAVQSGGSYLFTNKKQTLDDGTKPKIGTKHGVNDNISSF
                     TILTQNIIDTYGLDAKFHNEYIYPYGDLNYTYYDGTWAPKMIAKVWPKGENSGDPSKLQ
                     EVKNPYVIPYPVAEDDDRICFYLSKERLSDAEKAKRRYYVINIDDLFDNGQYRKTDIKV
                     TNDKNMYPGFNKYNWLSEDSYSSNLQRKTGDVFIMRMAEVYLIAAEANQQLGNGGKAAE
                     YLNVLKKRAARNDASYNAMKLSNATQNDVMDEYARELCGEYQRWVLMKRHKDSFKQRLA
                     VGNPRAAENFDENKHYLRPISFNFLSQIDNAEEYGNNGY"
     CDS             complement(5350..8223)
                     /locus_tag="ctg3_221"
                     /transl_table=11
                     /translation="MVSDTQALDEVVVVGYGTMKKRDLTGAITSVKSEDVVMNPSSNPM
                     QALQGKVAGLDITRESGQAGSGVKMQLRGNRSFQKDSGNPLFIIDGMPGDYSTLNPNDI
                     ESIEVLKDASSTAIYGSSGANGVILITTKGGKEGKAIVNFNAYVGVNGWSRTPEMRSGE
                     SYIQTLRDASVGAGDGRWSSVADDKNLFTTDAEWNAHQNGQYIDWVDALLKTSVTQNYS
                     VSVAGGTENTKAYFSLNFSNEDGQFAQDSYKLYSSKIRVDHKIKKWMKVGIDAQLSYVH
                     QNKADSDLQTLMASNPLGSLYNEDGSINPQPVADPSSTVYNYLLNEDKSLYRNQAQNLK
                     VYYNPYLEITPLKGLTFITRAGANLGYSRSNTFTGEGSVQWYKANQTADGIKAQVKDNR
                     SYNYKWENILTYNFQIKKVHDITLTAVTSWNHNRSDVTTLYQKGVSDNKFLWHNILDGN
                     SATSGSTSYSMSKGMGYVGRLNYSYMGRYLFAASVRHDGSSRLAEGNKWDTFPAFSLGW
                     RISDEKFMESTTNWLSNLKIRFGYGVTGSTAGIDPYSSAASLDATAVNMILGGVLTPIY
                     KFSQNIPNYLLTWEKSYNTNIGIDAAFLNNRIDVSMEYYNTKTKDVIWNKALPVINGAF
                     SPDGGSKANYTTNLNMCETSNKGFELALNTRNIITKNFTWSSSVTFNHNKEKITKLSGG
                     DSDVLNNGDTGYALALGEAINSYYHYKLDGVWQKGEETDAAVFGAAPGDLKINIPNLVK
                     ESDGRFYKIDEETGSAAVDENGNVIYYTSDNKYTPSDADYQILGHNSPDWSLGFQNNFT
                     WKDFDLSVFVYARYGQMFAYDMLTSYDPKGIRNFPTYFNYWTENNPSNDFPAANANKGL
                     EQYTGYYALRYVDGSFIKIKNITLGYSLPKSILKSAGIEKCRFYATITNPFVFAKSHLL
                     KDYDPEMNGSLKYPLTKQFVFGVNVTF"
     CDS             complement(8195..8587)
                     /locus_tag="ctg3_222"
                     /transl_table=11
                     /translation="MRCNAFVEAWKNHHRRASMILGLSLLSAPLSYSVYAEDGVSNTMV
                     QVVTQTKTVKGTIIDESGEPLIGVSIVVKGTSTGTITDFNGNFSINLPAGRKELVISYI
                     GYKEQTVTVTGNTGQCENGFGHTGIG"
     CDS             8827..9825
                     /locus_tag="ctg3_223"
                     /transl_table=11
                     /translation="MPLKLTTYYHGKDIPELPGKNTFHSKELFLIYEATPGYTPLLIVA
                     TEDGRPVARLLAAIRKAKKWLPSSLVKHCVVYSEGEFLDESLSTNKEKAEEVFGDMLEH
                     LTQEASRSCVLIEFRNLNNSMFGYRVFRANDYFPVNWLRVRNSLHSMKKTEDRFSPSRM
                     RQIKKGLKNGARVEEAHTVEEIHDFSRMLHKVYSSRIRRYFPANDFFRHMNDMLIKGQQ
                     AKIFVVKYKEKIIGGSVCIYSGDDAYLWFSGGMRKTYALQYPGVLAVWKALEDAHQRGF
                     RHMEFMDVGLPFRKHGYRDFVLRFGGKQSSTRRWFRVNWSWLNKLLVKFYV"
     CDS             10001..10405
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Glyoxalase_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_224"
                     /sec_met_domain="Glyoxalase_4 (E-value: 1.7e-21, bitscore:
                     75.1, seeds: 51, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKISHIEHLGIAVKSIEEALPYYENVLGLKCYNIETVEDQKVRTA
                     FLKVGETKIELLEPTCPESTIAKFIENKGAGVHHVAFAVEDGVANALAEAEGKEIRLID
                     KAPRKGAEGLNIAFLHPKSTLGVLTELCEH"
     CDS             10434..10970
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_225"
                     /sec_met_domain="CT_Btheta (E-value: 4e-80, bitscore:
                     268.3, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSNQLEKIKELIERRAVARIGGGEKAIAKQHEKGKYTARERLAML
                     LDEGSFEEMDMFVEHRCTNFGMEKKHYPGDGVVTGCGTIEGRLVYVFAQDFTVSAGSLS
                     ETMSLKICKIMDQAMKMGAPCIGINDSGGARIQEGINALAGYAEIFQRNILASGVIPQI
                     SGIFLVPAVLFILRL"
     CDS             10985..11983
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: CT_Btheta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_226"
                     /sec_met_domain="CT_Btheta (E-value: 3.4e-186, bitscore:
                     618.2, seeds: 72, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMEGTSYMFLTGPKVVKTVTGEDVSQENLGGASVHSTKSGVTHFT
                     AKTEEEGFELIRKLLSYIPQNNLEEAPYVDCTDPIDRLEDSLNDIIPDSPTKPYDMYEV
                     IGAIVDNGEFLEIQKDYAKNIIIGFARFNGQSVGIVANQPKYLAGVLDSNASRKGARFV
                     RFCDAFNIPIVSLVDVPGFLPGTGQEYNGVILHGAKLLYAYGEATVPKVTITLRKSYGG
                     SHIVMSCKQLRGDMNYAWPTAEIAVMGGAGAVEVLYAREAKDQENPAQFLAEKEAEYTK
                     LFANPYNAAKYGYIDDVIEPRNTRFRVIRALQQLQTKKLSNPAKKHGNIPL"
     CDS             12015..12509
                     /locus_tag="ctg3_227"
                     /transl_table=11
                     /translation="MNKTKIGIFLSLLLLIGLTSCGEQKSNNKLVLNEILIDNQNNFQD
                     DYGLHSAWIEIFNKSFGSADLAACLLKVSSQPGDTVTYFIPKGDILTLVKPRQHALFWA
                     DGEPNRGTFHTSFKLNPETANWIGLFDSGRKLLDQIVVPAGVLDPTSHTLVSATEQRSG
                     R"
     CDS             12578..12934
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_gamma"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_228"
                     /sec_met_domain="OAD_gamma (E-value: 4.4e-14, bitscore:
                     51.4, seeds: 234, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEKFEEHDADGVGMSISAMSVVFCGLILLFIAFKIVGKVAVNLSK
                     RNAMKSKGIDKHEAKELSQAPGEVYAAISMALHEMQDEVHDVEETVLTITRVKRSYSPW
                     SSKIYTLRETPPRK"
     CDS             12959..13390
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: Biotin_lipoyl"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1024:Biotin-requiring enzyme (Score: 67.7; E-value:
                     2e-21)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_229"
                     /sec_met_domain="Biotin_lipoyl (E-value: 2.2e-19, bitscore:
                     67.7, seeds: 40, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKEYKYKINGNSYKVTIGDIEDNIAHVEVNGTHYKVEMEKQPKPA
                     AKPVTVRPMPNAPTAPTQVVKPTAPSTGKSGVKSPLPGVILDIKVNVGDTVKKGQTIII
                     LEAMKMENNINADKDGKITAINVNKGDSVLEGNDLVIIE"
     CDS             13392..14552
                     /gene_functions="biosynthetic (rule-based-clusters)
                     succinate2propionate: OAD_beta"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_230"
                     /sec_met_domain="OAD_beta (E-value: 1.3e-149, bitscore:
                     496.5, seeds: 229, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGDFINFLGNNLADFWTYTGFANATVGHVVMILVGLGFIYLAVAK
                     EFEPMLLIPIGFGMLIGNIPFNMDAGLKVGIYEEGSVLNILYQGVTSGWYPPLIFLGIG
                     AMTDFSALISNPKLMLIGAAAQFGIFGAYMIALEMGFDPMQAGAIGIIGGADGPTAIFL
                     SSKLAPNLMGAIAVSAYSYMALVPVIQPPIMRLLTTKNERVIRMKPPRAVSHTEKVIFP
                     IIGLLLTCFLVPSGLPLLGMLFFGNLLKESGVTRRLANTASGPLIDTITILLGLTVGAS
                     TQASEFLTLDSIKIFALGALSFIIATASGVIFVKIFNIFLKKGNKINPLIGNAGVSAVP
                     DSARISQVIGLEYDSTNYLLMHAMDPNVAGVIGSAVAAGILLGFLM"
     CDS             14847..16187
                     /locus_tag="ctg3_231"
                     /transl_table=11
                     /translation="MKRIIILFFLCCTIPLIAQHTDPIQEAMANYDYETTLSLIAQKKT
                     TPPLLLQKGKALRGLGLTTEALATYQEIICNDTTNTRAFIEAAECCRALAKYNQALKYY
                     EHALDLNPENKYVRIQYISLLLSQQKFSEALGESSLMTEKDSSAIVLHLQAQSFEGMGE
                     LLPAAGCYYNIQAKYPDDYLAASKLGALNISGSYFDEAIEATEKYRQIDSTNISVNRQN
                     ALAYCLKQDYPTAIQRYEYLVSQGDSSFHTCYYLGISYYAAEKYYEAHDFLEVARKYDP
                     NNINLLYYLGRACSKTSWKKEGVDYLEKAIDLSIPKDSSMTRLYIGMTDCYKMAQMYKE
                     QIASIKERYQRYDKQNHKLLYDMAYIYFYDLKDKKNAERYLEAFLKTRPKDTKEEAEMN
                     ERGELVLGKSNYYNAAANWLKDIQSKQKIEDFFQNSSPQLPLPKKDK"
     CDS             complement(16342..17277)
                     /locus_tag="ctg3_232"
                     /transl_table=11
                     /translation="MVNYKDLGLVNTREMFAKAIKGGYAIPAFNFNNMEQMQAIIKAAV
                     ETKSPVILQVSKGARQYANATLLRYMAQGAVEYAKELGCAHPEIVLHLDHGDTFETCKS
                     CIDSGFSSVMIDGSHLPYEENVALTKKVVEYAHQFDVTVEGELGVLAGVEDEVSSDHHT
                     YTDPEEVIDFATRTGCDSLAISIGTSHGAYKFTPEQCHIDPKTGRMVPPPLAFEVLDAV
                     MEKLPGFPIVLHGSSSVPEEEVETINKYGGALKAAIGIPEEELRKAAKSAVCKINIDSD
                     SRLAMTAAIRKVFAEKPAEFDPRKYLGFGS"
     CDS             17700..17954
                     /locus_tag="ctg3_233"
                     /transl_table=11
                     /translation="MKKGLHPESYRPVVFKDMSNGDMFLSRSTVATKETIEFEGETYPL
                     LKIEISNTSHPFYTGKSTLVDTAGRVDKFMSRYGDRKKK"
     CDS             complement(18035..19249)
                     /locus_tag="ctg3_234"
                     /transl_table=11
                     /translation="MINREQYMEQIVPFIDKPFVKVITGIRRSGKSVVLRLIRDELLRR
                     GVREERIIYLNFESFQWIDLKEAKALYAYIRGQAGDAGKYYILLDEIQEVDGWEKVVNS
                     LLVDLDTDIYVTGSNSRMLSSELATYLTGRYVAFHVMTLSFREYLTFHDLQANDPTLNR
                     KEEFQKYLRMGGFPAIHTADYGYEAIYKIVYDIYSSVILRDTVQRHNIRNVELLERVVK
                     FVFDNIGNKLNAKNIADYFKSQQRKVDMNTIYNYLNALESAFIIQRISRYDIKGKEILQ
                     TNEKYFVSDLSLIYSVMGYRDRLIAGMLENLVCLELKRRGYEVYVGKQDDKEVDFVAIR
                     REEKIYVQVTYQLASQATVEREFAPLLAINDHYPKYVVSMDSLWQDNVEGVRHRHIADF
                     LLDDA"
     CDS             19443..19850
                     /locus_tag="ctg3_235"
                     /transl_table=11
                     /translation="MEITDLKQMTKEEVFNFIRQRLSFSKELQEQFRHVNKDDLAKEHR
                     RFEMSGNESKTGQCTIFNTAILNEFADLGIYDYTSYLFLDFHNGTPTVYLKYFSENENL
                     EYTFTGYTTTEIIFAILELTIFSGKPKRNRS"
     CDS             20586..21017
                     /locus_tag="ctg3_236"
                     /transl_table=11
                     /translation="MPKWISVEKAVIKYHIEKEAILLWVEMGQFPMLYIDNVPNVDEEC
                     ILELFRRSKAGITAEYIDTLEQLCIDKTMVCEKYAHIIQLKEKEIQLQKEINTLINEIQ
                     AAMKRQNERIRDLKKAIGENNNVIRSDSWIKRLRKRFQW"
     CDS             22104..23159
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_237"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 1.6e-10,
                     bitscore: 39.2, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKNFGFVLAAAILLAGCGQKKETTTTTARPVKTTIVESRSIIRK
                     DFSGIVEAVEYVKLAFRVNGQIIQLPVIEGQKVKKGQLIAAIDPRDIALQYAATKSAYE
                     TASAQVERNKRLLSRQAISVQEYEISLANFQKAKSEYELSANNMRDTKLTAPFDGSIEK
                     RLVENYQRVNSGEGIVQLVNTHNLRIKFTIPDAYLYLLRAKDPRFLVEFDTFKGHVFQA
                     KLEEYLDISTDGTGIPVSITIDDPSFDRDLYAVKPGFTCSIRFTADVGPLVQDSWTIVP
                     LSAVFGESEGNKMYVWVVEDNKVHKREVTVNAPTGEAQALISEGLKPGEKIVIAGVYQL
                     VEGESITTVDR"
     CDS             complement(23570..24046)
                     /locus_tag="ctg3_238"
                     /transl_table=11
                     /translation="MILDGGIHVPFFDDGDIAQFHLSGFGGNHLVADIVYGGIHTVGGH
                     PELLLAGTDFSGIDNLVLRLQQTGKLFRVDAHTYELIGGNKNIDHLRLRPEQGDFHHPV
                     CRHYLRLDPFRPVAHLFVCVTVVRRQTVIDTEHVAEIIGNRRCGSTARQLWLYI"
ORIGIN
        1 ttttattcgt tattaaacaa cgattattta tgattaagtt accaaccgaa ggcgtcttcc
       61 accatccata gaccgtgagc tttcagcacc tgctccacta catcacgtcc gcatccacga
      121 ccaccgtctg cataagaaat atactttgca acggatttca cttccggcac ggcatctttc
      181 gggcagcatg gcagtccgca ctcacacatc acttcaatat ccggcacgtc atcacccata
      241 tatagaattt catcatcggt caatccgtac ttatcacgaa aagcacgata atcatgtatc
      301 ttcacagcag aacccatgta taaatccttc actcccagtc cctcaaaacg gatacgtacc
      361 gcttctgtcc ggccaccggt gatgatagct atgtgaagtc ctttttcaca gccaactgga
      421 tggcgtaccc atctttgata ttcaccgtgc gcatcggttc tccggaagga tgcaaaggta
      481 cggttgtcga actcaatact ccgtccacat caaaagctaa agctttgata cgggataaat
      541 cataattgat ggtgctcatg gatacttttg ctcattagtt tatatatttc ctgcaatgcc
      601 ggagaatcta ccaacatggc aagatgatta ctcatcacat tctcatcgta acgaacagcg
      661 ggtctggtct gtgcatcacg tggcgccaat tcgtggactt tacgtgctgt ttcatctatc
      721 agcggaagca tgacatcgaa aggcaagttg tatttttcaa gcaaatcagc tgctaatgca
      781 tacatgtgat tggtgaagtt acagataaaa acagcagcca aatgaaggct cttacgttgc
      841 tcggaagaag cctcgtagac cttttccgaa agtgtggcgg caacagcctt caacaattcc
      901 acgtcttccg gccttttcgc ttcaacaaag aaaggcactt cctgaaattt aacttcacgt
      961 tgtttgctga atgtctgcat cggataaaat actccgtaac gttctgcatg cccttcccaa
     1021 acgctcatcg gaatgcttcc tgccgtatgc accaacaaag acgcttgctt tccttctgtt
     1081 atctgcggta acaaatctac taaagcatca tctttcaacg atacgatata caattttgca
     1141 tctttggaga ctgcctgtaa atctgttgta tattcagctt ctactttctc ggctaaggta
     1201 cgggcagatt ccatagtccg gctatatacc tgtacaatgc ggaaaccttt acgataaaga
     1261 gctttcgcca gattagtagc caagttacct gcaccgataa acacgatcgg tgtatcttct
     1321 atacttcttt tcattattct cttatcgttt tgcaaaccag aataaaacga ttccgatgat
     1381 gagcagtgtc aatggcaaca gatatccgga taacgaaccc aataaggaca tgaccaaacc
     1441 gatattcatc actagccaaa gcccaagcaa cacaaaacca attgatttat cgcgtttgaa
     1501 aataaggaaa cagatcgagg cgtacaatag catattgtcc ttattcatca cccaaggcag
     1561 tccaatggaa gagaaatgaa tcagtttatc aatcagataa agtgctccga taacgataaa
     1621 ggtaacagca gtagccagat aggtatcttt actattattc gctttagcag ctcccatact
     1681 tattttcctc cgaacttgtt aatatgaatt ttctcccatt gaagatgttc ttcattgaaa
     1741 ggtttacgtt ccatcccttt atgtccgata gcaatgacag aaagaatctg aagttgcaag
     1801 ggaatatcca aaattccatg gacaaattca tcggaaggca ttccggtggc agtgaaacgt
     1861 tcgcgaacct gcacccaaca acttcccaag ccaagatctt cagcctgcaa ctgtatcatg
     1921 atggaagcaa tggaagcgtc ttcaatccaa acatcgctgg ccaacggatc ggccattaca
     1981 acaatcgcca aagctgcatc ggcaatgaac gaagaagcct gttctttgca atgagacaat
     2041 tctttcaata cctctttatc atcaaccact acaaactgcc aactattact acgtttggaa
     2101 gaaggggaca tcaaagctgc tttcatcaac gcaactacct gatcttgtgt caattcttca
     2161 tcggtgaact tccgcatact acgacggttc tttattaatt cactgaaatt ttccatatta
     2221 tttccggttt catttgatta atgtatgcaa agataatgca aaccgagcgt aataggaaat
     2281 aaaagtttat actaaatgaa gaatatattg tatctttgca cagagaaata atttcattat
     2341 gaaaaagcga attacacagg acgattacgt taaagcgaat cgtaaagcta gccgtgaggc
     2401 agaaattgag atgtacgggc accctatttg tcacaaacga gtgcaccagt caaagaaagt
     2461 atataaccgc agaaagataa aggcagccga taaaaagctg ccttattttt ttgtcttcaa
     2521 aatagcgtca ctatcctcca gacatagcga cactatacaa tagaaatggc gtcactatca
     2581 tgataggata gcgtcactat atttagggga ttaaaaaaga agtttatcta tttacctatc
     2641 tatctaataa tctatacaat ccgagttaat tctccggtcg tagaatcaat aataaacccg
     2701 tagactgtca catctgaagg gatcaaagga tgacgcacaa taaaatctac cgttcctctc
     2761 accgactttt ctgtatcttc gaaaccatcc agccacgaat gaaagtcaac tccgcagaaa
     2821 cgcatcatat caatataatc cggattgatt ccgcgtgctt tcattttttc gagcattact
     2881 tcactgtgca tgtggcaagc tccacagtca gaatgagcaa tcaccattat ttcctctacc
     2941 cccaactcaa aaatagctac aagtaaacta cgtatcacgc taccgaaagg atgggaaata
     3001 acgccacctg cattttttat cattttcaca tcgccattct taattcctaa tgctgctggc
     3061 agcaaagcag tcagtcgggt atccatacag gaaagaatag ctattttctt atcgggatat
     3121 ttattggtaa tatacgattc gtatcccttg ttctcaacaa attgcttgtt gtaagctaaa
     3181 atttcttcta acatagttcc gctttttaaa agttctgttc gattacacaa agatatagaa
     3241 aaaagggaca tatcatcacg acatatcccc tctttaatct aaatttaatc tgtaagagta
     3301 ctaataccca ttgtttccat attcttctgc attatcaatc tgactcaaga agttaaaaga
     3361 aatcggacgc aaataatgct tgttttcatc aaaattttca gctgcacgag gattaccaac
     3421 agcaagacgt tgtttgaaag aatctttgtg acgcttcatc aatacccaac gttgatattc
     3481 tccacataat tcacgagcat attcgtccat aacatcattc tgtgtagcat tactcaattt
     3541 catagcattg taagatgcat cattgcgagc ggcacgcttt ttcagtacat ttaaatattc
     3601 agcagctttt ccgccatttc ctaattgttg gttagcttca gctgcaatca gatatacttc
     3661 agccatacgc ataatgaaca catcacctgt cttacgttgc aaattgctac tatatgaatc
     3721 ttccgacaac caattgtatt tgttgaaacc agggtacata tttttgtcat tagtgacttt
     3781 tatatctgtt ttacgatatt gtccgttatc aaacaaatca tcaatattga ttacataata
     3841 tctacgtttc gctttctccg catccgaaag tctttccttt gataagtaga aacagattct
     3901 atcatcatct tcagctacag ggtaaggtat cacatagggg ttcttcactt cctgcaattt
     3961 ggaaggatca ccgctatttt cacctttcgg ccaaaccttg gctatcattt tgggcgccca
     4021 agttccatca taatatgtat aattcaaatc accataagga taaatatact cattatggaa
     4081 ttttgcatcc aatccataag tatcgattat attttgagta agaattgtaa atgaactaat
     4141 attatcattt acgccatgtt ttgttccaat ttttggtttt gtaccatcat ccaatgtctg
     4201 cttcttatta gtaaataaat aactacctcc tgactgtacg gcagaaaact gtacaaaagc
     4261 cgtagtaaag gttacttccc accgcttatc ataatcagca tcaaaacaat ccagcaaata
     4321 tttggaaggt gccaacgtat tattattggt acgtccatac caataattct gattatccgg
     4381 agtaggataa atagtgagag tatttggctt tggatacata taagtaaagt tattattaca
     4441 ttgtgttcca gcattccaat tctccaaatt cgtagcatcc ggaccggcag caataaataa
     4501 agcttcttta ttatttcgat tatttgccgg agcccaaaca tcttccacat catcatacaa
     4561 acagtcacca tacgctaaaa tcatgtcctc tgccacttct ttagcacgtt gccaataaga
     4621 tactccatct tctgtcagcc catattcgcc accaccttga gcataaacgc gagccaaaag
     4681 tcctaacgcg gttttcttag tcacacgcgc acgattacta tcataaggag tatcttcaag
     4741 attattggcc gcaaatttca aatcatcaat tatctgcgta tatagttctt caatagagtt
     4801 acgctgcgga gtcaaaatag gatcttgaga cgattcttcc aatgttaacg ttacatttcc
     4861 atacgtattc accaatatgg aataataaaa cgcacgaaga cagcgggctt cagccactaa
     4921 agtcgttata tctttttcat tgccatccgt tagtaattca gccctgttta ctactgcatt
     4981 acaattaccg atcatagaat aagcctgacc gaataattta tttgtagcat tcgtattcgt
     5041 agctaaacca tcataataaa tcacctgctt ggcataatcc ggattaccgg caggagttat
     5101 ccagcagtcc gtaccacctt cagccacaga caagaaatca tagacactga ataactgccc
     5161 gtaaagtgat gaataacaat aagactgtaa tcctttaagc ccatcgaacg ttgcaagaat
     5221 ttcatctcct gttttttggc ttggattata ctcatcaagc gagcaggcag acattgaagc
     5281 cacagcgaat gtaagcgctg ctattttata gattgtactt ttcatttcaa tacttttttt
     5341 agtgaaaaac tagaatgtaa catttacacc aaatacaaat tgtttggtca atgggtactt
     5401 cagagaacca ttcatttccg gatcatagtc tttcagcaaa tggcttttcg caaatacaaa
     5461 cggatttgta atggtagcat agaaacgaca cttctctata ccggctgatt ttaagataga
     5521 tttcggcaga ctatatccca atgtaatgtt cttaatcttt ataaacgaac cgtctacata
     5581 gcgtaatgcg taatatcccg tatattgttc gagaccttta ttagcattgg cggcaggaaa
     5641 atcatttgaa gggttgtttt cagtccaata attgaaatag gtcgggaagt tacgtatacc
     5701 cttcgggtca taagacgtca acatatcata agcaaacatc tgtccgtaac gtgcataaac
     5761 aaacacactt aaatcaaaat ccttccaggt aaaattattc tggaatccta aagaccaatc
     5821 cggagagttg tgacccagaa tttgataatc tgcatcactt ggagtatatt tattatcaga
     5881 agtgtaataa ataacattac cattttcatc cacagcagca ctacccgttt cttcatctat
     5941 tttatagaat ctaccatcag attcttttac taaattaggt atattgattt tcaaatcacc
     6001 aggtgcagca ccaaataccg ccgcatcagt ttcctcacct ttttgccata caccatccaa
     6061 cttataatga taataagagt taatagcttc tcccaatgcc aatgcataac cggtgtcacc
     6121 attattaagc acatctgaat ctccaccgga caatttggtt attttctctt tattatgatt
     6181 gaaagttaca cttgaactcc aggtaaagtt ctttgttata atattacgtg tattaagagc
     6241 caactcaaaa cctttattgc tagtctcaca catatttaaa ttagtagtat aattcgcttt
     6301 agatccgcca tccggggaga atgctccatt aataacagga agtgccttgt tccatataac
     6361 atcttttgtt tttgtattat aatattccat actgacatca atgcgattat ttaagaatgc
     6421 agcgtcaata ccaatattcg tgttatacga cttttcccat gtaagcaaat agttcggaat
     6481 attctgtgag aatttataaa tcggtgtcag aacacctcct aatatcatat ttacagcagt
     6541 agcatccaat gatgcagcag acgaatacgg atcaatcccc gctgtactac ccgtaacacc
     6601 atatccgaag cggattttca gattactcaa ccagttagtc gtactctcca taaatttttc
     6661 atcagaaatt ctccatccca aagaaaaagc cgggaaagta tcccatttat taccttctgc
     6721 cagtctggaa gagccgtcat ggcggacaga tgcagcaaat aaatacctac ccatatatga
     6781 atagttcaaa cggccgacat atcccatccc cttagacata ctataagaag tacttcccga
     6841 agttgcggaa ttaccatcaa gaatattatg ccataagaat ttattatcag aaacaccttt
     6901 ttgatacaaa gtagtgacat cgctacgatt gtgattccac gatgtaactg cagtaagagt
     6961 tatatcatgc actttcttaa tctggaaatt gtaagtaagt atattttccc acttataatt
     7021 atacgaacgg ttgtccttaa cttgcgcctt aatgccgtct gccgtttgat ttgccttata
     7081 ccattgaaca gacccctctc ctgtgaaagt gttactacgt gaatatccca aattagcacc
     7141 agcacgagta ataaaagtca gtcctttaag aggagtgatt tccaagtaag gattataata
     7201 gaccttaagg ttttgagcct gattgcggta caaactttta tcctcattta aaagataatt
     7261 atatactgta gatgaaggat cggcaacagg ttgcggattg atgcttccat cttcattata
     7321 caacgatcca agaggatttg acgccatcaa agtctgtaaa tcagaatcag ctttattttg
     7381 atgtacataa gacagttgag catcaatgcc caccttcatc cactttttaa tcttatgatc
     7441 tacccggatt ttagatgaat aaagtttata actatcttgt gcaaactgcc catcctcatt
     7501 agagaagttc agagaaaaat atgcctttgt attttccgtt ccaccagcca cagaaacaga
     7561 ataattctgt gttacactgg ttttcaacaa agcatccacc caatctatat attggccatt
     7621 ttgatgtgca ttccattcag catcagtagt aaacagattt ttatcatcag caaccgagct
     7681 ccaacgtcca tcgccagcac caacagatgc atctctcaag gtttgtatat aactttctcc
     7741 actacgcatc tccggagtcc ttgaccagcc gtttacacct acgtatgcat taaaattaac
     7801 aattgctttg ccttccttac cacctttagt agtaattaaa ataacaccgt tcgcaccact
     7861 tgaaccataa atagctgtcg aagaagcatc ttttaaaact tcaatgcttt caatatcatt
     7921 cggattcaat gtagaataat cccccggcat accatcaatt ataaataaag gatttccgga
     7981 atccttctgg aatgaccggt taccacgcaa ctgcatcttt actcccgaac cggcctgtcc
     8041 cgattcacgc gtaatatcca atcctgccac cttaccttgt aaagcctgca tcggatttga
     8101 acttggattc atcactacat cttcactttt tacagaagtg atagctcctg tcaaatcgcg
     8161 ttttttcatc gtaccgtaac ccacaacaac cacttcatcc aatgcctgtg tgtccgaaac
     8221 cattttcaca ttgaccggtg ttgcccgtca cagtcaccgt ttgttctttg taaccgatat
     8281 aagaaatgac cagttctttt cttcccgccg gaagattgat agagaagtta ccgttaaaat
     8341 cggtaatcgt acctgtactt gttcctttca caacgataga aaccccaatc aacggctccc
     8401 cgctttcatc aatgatagtt cctttcacag ttttcgtttg tgtgacaact tgcaccatag
     8461 tattagaaac tccatcttct gcatacacag aatatgacag aggggcagac aataaagaca
     8521 gccctaaaat catggaagcg cgtctatgat gattcttcca tgcttcaaca aatgcattac
     8581 atctcattcg ttctaattta aagttaatat taattctcgt tgttttgcaa aaactattcg
     8641 attataatct taattaaaga cgaatctaat tttaatacgt actcactttt cataccatat
     8701 ttctcctata aaatatattt tctccattaa atacgcaact atatattata ctttacttca
     8761 agcagctcca acaaattctt tattttgttg ttgaataaag aataaaaagt gtaaatttgt
     8821 acctagatgc cactgaaact aacaacatat tatcatggga aggatattcc tgaattgccg
     8881 ggaaaaaata ccttccattc caaagagtta tttctgattt atgaagcaac tcctgggtat
     8941 actcctttat taatagtggc aacagaagac ggcagaccgg tggcacgcct gcttgctgcc
     9001 atccgcaaag caaagaagtg gctcccttct tctttagtga aacattgtgt agtatatagt
     9061 gaaggcgaat ttctggacga gtctctttcg accaacaaag aaaaggcaga agaagtcttc
     9121 ggcgatatgc tcgaacatct cacacaagaa gcatcgcgca gctgtgtcct gatcgaattc
     9181 cggaacctga acaattcgat gttcggctat cgggttttcc gtgccaatga ttatttccct
     9241 gtcaattggt tgcgggtacg caattcgctg cacagtatga aaaagacgga agaccggttc
     9301 agtccgtcgc gtatgcgtca gataaaaaaa ggactcaaga atggagccag agtagaggaa
     9361 gcacataccg tggaagagat acacgatttc tcacggatgc tgcacaaggt ttattcctcc
     9421 cgcatacgca gatatttccc tgccaacgac tttttccgcc acatgaacga tatgttaatc
     9481 aaaggacaac aggcaaaaat attcgttgtg aaatacaaag agaaaatcat tggcggttct
     9541 gtctgtatct attcgggaga cgacgcatac ctttggtttt cgggaggaat gagaaagaca
     9601 tacgcacttc aatatccggg tgtgctagct gtttggaaag cattggaaga cgcacaccaa
     9661 cggggattcc gccacatgga atttatggat gtaggacttc cgttccgtaa acacggttat
     9721 cgtgatttcg ttcttcgctt cggaggaaaa caaagcagta cccgccgttg gttccgcgtc
     9781 aattggagtt ggctgaataa actcttagtc aagttttatg tctaaatgta atctcaagat
     9841 tacaaaacaa tgttttatgc tcctttccca ccattttttc tgtttaataa tccaataatt
     9901 aaatgcagaa atatttcttt attagataag aaatgtcttt ctttgtgctg ttttatgcct
     9961 tataagcaca gatttaaaac caaataaaaa aagtatagtt atgaagattt cacacattga
    10021 acatctgggc attgctgtaa aaagcatcga agaagccctt ccttactacg aaaatgtatt
    10081 aggtctgaag tgttacaaca ttgaaacagt ggaagatcag aaagtaagaa ctgctttttt
    10141 aaaagtgggc gaaacaaaaa ttgaactgtt ggagcctact tgcccggaga gtactattgc
    10201 caaattcatt gaaaacaaag gtgcaggcgt tcaccacgtc gcatttgctg tagaagatgg
    10261 cgtagccaat gcgctggcag aggcagaagg caaagaaatc cgccttatcg acaaagctcc
    10321 ccgcaaaggt gctgaaggtt tgaatatcgc tttccttcac ccgaaatcaa ctttgggtgt
    10381 gttaacagaa ctctgcgaac attaatcata aactctaaaa ccaacaagaa ctcatgagta
    10441 atcaacttga aaaaattaaa gagcttattg aacgccgtgc cgtagcacgt atcggaggcg
    10501 gtgaaaaagc aattgcgaag caacacgaaa aagggaaata cacagcacgc gagcgtctgg
    10561 ctatgctgct tgacgagggt agcttcgaag aaatggacat gttcgttgag cacagatgca
    10621 cgaacttcgg catggagaaa aaacattacc cgggagacgg tgtagtaacc ggctgcggta
    10681 cgatcgaagg acgtctggta tatgtgttcg cacaagactt cactgtttct gccggttcac
    10741 tgtcagaaac gatgtcattg aaaatttgta aaatcatgga tcaagccatg aagatgggcg
    10801 ctccctgtat cggtatcaac gactcgggtg gtgcacgtat tcaggaaggt atcaacgctt
    10861 tggcaggtta tgcagaaatc ttccaacgca atatccttgc ttccggtgtt atcccacaga
    10921 tttcaggtat cttccttgtg ccggcggtgc tgtttattct ccggctctga ccgacttcac
    10981 gctaatgatg gaaggtactt cttatatgtt ccttaccgga ccaaaagttg tgaagaccgt
    11041 aacaggtgaa gacgttagcc aggaaaacct cggtggcgca agcgttcact ccactaaatc
    11101 aggtgtgact catttcaccg ctaaaacaga agaagaaggt ttcgaactga ttcgtaaact
    11161 gttgagttat attcctcaaa acaaccttga agaagctcct tatgtagatt gtacagaccc
    11221 aatcgaccgt ctggaagatt ctttgaatga tattatcccc gacagcccta ctaaaccgta
    11281 tgacatgtac gaagttatcg gcgctattgt ggacaacggt gagttccttg aaatccagaa
    11341 agattatgca aagaatatca tcattggttt cgcccgtttc aacggacaat cggtaggtat
    11401 tgttgccaat cagcctaagt atctggctgg tgtgctcgac agcaacgcat ctcgcaaggg
    11461 tgcacgtttc gtgcgtttct gcgatgcatt caatattcct atcgtatcgt tagtagacgt
    11521 accgggattc cttccgggaa caggtcagga atacaacggc gttatccttc atggtgctaa
    11581 gctattgtat gcttacggtg aagctactgt gcctaaggtt actatcacat tgcgtaaatc
    11641 ttacggtggt tctcacatcg taatgagctg taagcaactt cgcggtgaca tgaactacgc
    11701 atggccgact gctgaaatcg cagtaatggg tggagcagga gcagtagaag tattgtacgc
    11761 acgcgaagcc aaagatcagg aaaatcccgc tcaattcctt gctgaaaaag aagcagaata
    11821 cacgaaactg tttgccaatc cttacaatgc agccaaatac ggctacatcg atgatgtgat
    11881 tgaaccacgc aacacacgtt tccgcgtaat ccgtgctttg cagcagttgc agactaagaa
    11941 attgagtaat ccggctaaga agcatggtaa tattccgttg taatcctact tttcacatta
    12001 aaacaagaac gattatgaac aaaaccaaaa tcggaatatt cctttctttg ctgttgctga
    12061 ttgggctgac ttcttgtgga gagcaaaagt cgaacaacaa gctggtactg aacgaaatcc
    12121 tgatagacaa tcagaataat tttcaagatg actacggatt gcacagcgca tggattgaaa
    12181 tattcaataa atcattcggt agcgccgacc tggcagcttg cttgttgaaa gtaagcagcc
    12241 aaccgggcga tacagttact tactttatcc cgaaaggtga tatacttaca ttagtgaagc
    12301 cacgtcaaca tgcactattc tgggcagatg gcgaacctaa ccgcggtact ttccacacca
    12361 gcttcaagct gaatccggaa acggccaact ggatcggtct gtttgactcc ggtagaaagc
    12421 tgctcgacca gattgtagtg cccgcaggtg ttcttgaccc aaccagtcat acgctcgtgt
    12481 cagcgacgga gcagcggagt gggaggtaaa aggtggaagt ggtgacaaat acgtgacccc
    12541 gagtacgaac aacaaaactc ttgacagcaa tgccaagatg gaaaaattcg aagagcatga
    12601 tgctgacggt gtcggcatgt ccatctctgc catgagtgta gtattctgcg gattgattct
    12661 tctctttatt gccttcaaga ttgtaggaaa agtagctgta aatttgagca agcgcaatgc
    12721 tatgaaatct aaaggcattg acaagcatga agctaaggaa ctgtcacagg ctccgggcga
    12781 agtttacgct gcgatttcta tggcattgca cgaaatgcag gatgaagtgc acgacgtaga
    12841 agaaacggta ctgaccatca ctcgcgtaaa acgcagttac tcaccatgga gttcgaagat
    12901 ttacactttg cgtgaaactc ctcccagaaa gtaagtcacc ttttaaaaag ttaaaacgat
    12961 gaaagaatat aaatataaaa tcaacggtaa ctcatataaa gtaaccatcg gagatattga
    13021 agataatatc gctcatgtag aagtgaacgg tacacactat aaagtggaaa tggagaaaca
    13081 gccgaagcct gctgccaaac ctgtaacagt acgtcctatg cctaatgctc ctactgctcc
    13141 tactcaggta gtgaaaccga ctgctccgtc taccggaaaa tcaggagtga aatctccgct
    13201 gccgggtgtt atcctcgaca tcaaagtgaa tgtaggcgat actgtaaaga aaggacagac
    13261 cattatcata ttggaagcca tgaagatgga aaacaatatc aatgcggata aggacggtaa
    13321 gattactgcc atcaacgtca acaagggaga ctctgttctt gaaggtaatg acctcgtaat
    13381 tattgaataa tatgggagat tttataaact ttttaggaaa taacctcgcc gacttctgga
    13441 catacacggg ctttgcaaat gctactgtag ggcatgtcgt tatgattctt gtgggtttgg
    13501 ggttcatcta tctggcggta gccaaagagt tcgaaccgat gctgctgatt cctatcggct
    13561 tcggtatgct gatcggtaat atacctttta atatggatgc cggactgaaa gtcggtattt
    13621 atgaagaagg ttccgtattg aatatattgt atcagggagt aacttccggc tggtatccgc
    13681 cgctcatctt tttgggcatc ggcgccatga cggacttctc ggcacttatc tctaatccga
    13741 aattgatgtt gatcggtgct gctgcacaat tcggtatctt cggtgcttac atgatcgcat
    13801 tggaaatggg cttcgacccg atgcaagccg gcgctatcgg tatcattggt ggagcagatg
    13861 gcccgacggc catcttcctt tcttccaagc tagcacctaa cctgatggga gccattgcgg
    13921 tgtccgccta ctcctatatg gcgttggttc cggtgataca gccgcctatc atgcgtctgc
    13981 tcaccaccaa gaacgaacgt gtcatccgca tgaaaccgcc gcgtgccgtt tctcacacgg
    14041 agaaggttat tttcccgatt atcggcttgt tgctgacctg cttcctggtt ccttccggtc
    14101 tacctttgtt gggtatgctg ttcttcggta acctgttgaa agaaagtggt gtaacccgtc
    14161 gtcttgccaa tacagctagc ggtccgttga ttgatactat cactatcctg ttgggtctga
    14221 cagtaggtgc ttctacgcaa gcttccgaat tcctgacgct cgattctatc aagattttcg
    14281 ccctcggtgc attgtcattc atcattgcaa ctgcatccgg tgtaatcttc gttaagatat
    14341 tcaatatctt cttgaagaag ggcaacaaga tcaatccatt gatcggtaat gcaggggttt
    14401 ctgctgtccc cgactctgca cgtatctcac aagtgattgg tttggaatac gattcgacca
    14461 actatttgtt gatgcacgct atggatccga acgttgccgg agtgatcggt tcagctgttg
    14521 ctgccggtat cctgctcgga ttcttgatgt aagatataag gaggctgttt gaacagttct
    14581 taaaataaaa aataagacta tcctaaaagc cttgaattta taaaaatcac ctttgctaca
    14641 ttatagtagt aaaggtgatt tttcattata aggacttgct gtaaaaaaga ctgtagctac
    14701 catgccccat gtattgtatt gcgcactgtt gtgttacctt ctcttatcat tccgttaatc
    14761 tatccaaaat aatctacgaa taattcgtaa atataatatt tttagtaact tgcagcagat
    14821 aagtcaaaca actaaaataa aatattatga aacggattat cattctgttc tttctttgtt
    14881 gtaccattcc tctaatagcg caacacacag accctattca agaagctatg gcaaactacg
    14941 attatgagac tactctttct cttatagctc aaaaaaagac tacccctccc ctgctattac
    15001 agaaaggcaa agcgttgcgt ggactaggac tcaccacaga ggcacttgct acctatcaag
    15061 aaattatctg taatgatact acaaatactc gtgctttcat tgaagcggcc gaatgttgcc
    15121 gagcactagc taaatacaat caagcactaa aatattatga acatgcactt gatctgaatc
    15181 cggaaaacaa atatgtacgt attcaatata tcagcttgct tctctcccaa cagaagttta
    15241 gcgaggcgct tggtgaaagt agtctgatga cagaaaaaga cagttccgcc attgtcctgc
    15301 atctacaagc tcaaagcttt gaaggaatgg gcgaacttct tcccgctgca ggttgctatt
    15361 acaatatcca ggctaaatat cccgacgatt atctggctgc cagcaaacta ggcgctctaa
    15421 atatatccgg ttcctatttc gacgaagcca tcgaagctac agaaaaatac cggcaaattg
    15481 acagtaccaa catttccgtc aaccggcaga acgctttagc atactgcttg aaacaagact
    15541 accccactgc catccaacgt tatgaatatc ttgtcagcca aggagacagt tcttttcata
    15601 cttgttatta tttaggcatc agttactatg cagcagagaa gtactacgaa gctcatgatt
    15661 ttttggaagt cgcccgtaaa tatgatccca acaatatcaa tctcctttat tacctcggtc
    15721 gcgcctgttc caaaacttcc tggaaaaaag agggcgtaga ctatctggaa aaagccattg
    15781 atctatccat tcccaaagat agcagtatga ctcgacttta catcgggatg accgactgtt
    15841 acaagatggc acaaatgtac aaagaacaga ttgcatccat caaagaacgc taccagcggt
    15901 atgacaaaca aaaccacaaa ctattgtatg acatggccta tatatacttc tatgacttga
    15961 aagataagaa aaatgcggaa cgctatttgg aagcattcct aaaaacacgt cctaaagaca
    16021 ctaaagaaga agcggaaatg aacgagagag gcgaacttgt tttaggaaaa tccaattatt
    16081 ataatgccgc cgccaactgg ctgaaagata ttcaaagtaa acaaaaaata gaagacttct
    16141 ttcaaaattc ctctccacaa cttcctctcc caaagaaaga taaatagata agaactataa
    16201 agcaactaaa aggctgctac cggtttatcg gtagcagcct ttcttttatt tatggaataa
    16261 tccggagatt attactgtgc caatttgttg tcagaaccga gcacattcag aattttgtgc
    16321 ttgtacagtt tttccatatt gtcacgagcc gaagccaaga tacttacgtg ggtcgaattc
    16381 agccggtttt tcagcgaata ccttacgtat agcagcagtc atagccagac gagagtcaga
    16441 gtcgatgttg attttgcaaa cagcagactt agcagcttta cgcaattctt cttccggaat
    16501 gccgatagca gctttcagtg caccaccata tttgttgata gtttccactt cttcttccgg
    16561 aactgaagat gatccgtgaa gaacgatagg gaatcccgga agtttttcca ttacagcgtc
    16621 caatacttcg aaagccaatg gaggaggaac catacggcca gtcttcgggt cgatgtggca
    16681 ttgttccgga gtaaatttgt aagcaccgtg agaagtaccg attgagatag ccaaagagtc
    16741 gcaaccagtg cgagtagcga agtcgattac ttcttcaggg tcagtatatg tgtgatggtc
    16801 ggaagaaact tcatcttcta caccagccaa tacgccaagt tcaccttcta cagttacgtc
    16861 aaactggtga gcgtattcaa caactttctt agtcaatgct acgttttctt cgtaaggaag
    16921 atgagaaccg tcaatcatca ctgaagagaa acctgaatcg atacaagatt tgcaagtttc
    16981 gaatgtatct ccgtggtcaa gatgaagaac gatttccgga tgtgcgcagc ctaattcttt
    17041 agcatattct acagcaccct gtgccatgta acgcaacaaa gtagcgttag catactgacg
    17101 agcaccttta gaaacctgaa gaatcacagg agatttagtt tcaacagcag ccttgatgat
    17161 agcctgcatt tgttccatat tgttgaagtt gaatgctggg atagcatatc cacctttgat
    17221 agccttagca aacatttctc ttgtgtttac caatcctaaa tctttgtaat ttaccatttt
    17281 gtttaaagtt tattgttagt gaataaaaat tctacgcaaa agtaagcatt atccatcgaa
    17341 taacgaacat cggaaagaaa aatatagtag aaaaaggttt aaatcagact gcaaaattta
    17401 gcaggaatac gagtgtgaca ttagattgta atgtccacct tgcaaacttt gggatttatg
    17461 atttctgaat tctgattgat gccttcggat ttatatctcc ttatttatac cttatttttc
    17521 attcatttga tcaccaaaat ctgcatagcc aatcagaaat cagaaattat aaatcagaaa
    17581 ttttagaaaa cctttttcta tttcacagaa aagcattatc tttgcgctct gaaaatgacc
    17641 attacactat ttcttaccaa aatagtaaca gaatataaat taaaaaaaca gatactgaaa
    17701 tgaaaaaagg ccttcatcca gaatcatacc gtccggtagt atttaaagat atgtcaaatg
    17761 gtgacatgtt tttgtctaga tcaactgtag caactaaaga aaccatcgaa ttcgaaggtg
    17821 aaacttatcc gttgctgaag attgaaatct caaacacttc tcacccgttc tatacaggta
    17881 aatctacatt ggtagatact gcaggtcgtg ttgacaagtt catgagccgt tacggtgacc
    17941 gtaagaagaa ataattcgat ctttcgtgaa agatgaaaaa agaggagatt ctcgcagaga
    18001 atttcctctt tttcgttttc tatattcctt aacgtcaagc atcatccaac aagaaatcgg
    18061 ctatatgacg atgcctgaca ccctccacat tatcctgcca caagctgtcc atgctaacta
    18121 catatttagg ataatggtcg ttaatggcga gcaaaggagc aaactccctc tcaacagttg
    18181 cctgtgaagc taactgatac gttacttgca cataaatctt ttcttcccga cggatggcta
    18241 caaaatccac ttctttatca tcctgtttgc ctacatacac ttcataaccc cttcttttca
    18301 actccagaca gaccagattc tccaacatac ctgcaatcaa ccggtcacga tagcccatca
    18361 cggaataaat caaagaaagg tcgcttacaa aatacttctc attcgtctgc agaatttcct
    18421 ttcctttaat atcataccgg gaaatacgtt gaatgataaa agcactttcc aatgcattca
    18481 gataattata gatggtattc atatccacct tccgttgctg acttttgaag taatcggcta
    18541 tatttttagc gttcagctta ttgcctatat tatcgaaaac aaacttcact acccgttcga
    18601 gcagttccac attccggata ttgtgacgct gcaccgtgtc acgaagaatg acagaagaat
    18661 agatgtcgta gacaatttta tagatagcct catatccata atcggcagta tgtatggccg
    18721 gaaatcctcc catacggaga tatttctgaa attcctcctt ccggttgagc gtcggatcat
    18781 tggcctgcaa gtcatggaaa gtcagatatt ctctaaaaga caaggtcatg acatggaaag
    18841 cgacataccg tcccgttaaa taagttgcca gttcggacga taacatacgt gagttggagc
    18901 cggtcacata aatatccgta tccaaatcta ccagaagtga gttgaccact ttttcccaac
    18961 cgtccacttc ctgaatttca tccaagagaa tataatattt acccgcatct cctgcctgcc
    19021 cccgaatata agcatacaaa gccttcgcct ctttcagatc tatccactga aaactttcaa
    19081 aattcagata gatgatacgt tcttcacgaa ctcctctcct caacagttcg tcacgaatca
    19141 gacgcagcac taccgacttt ccactgcgac gaatacccgt tatcactttt acaaacggct
    19201 tatctataaa aggaacaatt tgttccatat actgttcacg attaatcata ttcaaaagtt
    19261 tttagggtta taagcacaaa gatatactat tttcggaaag tttttagggt tataagcata
    19321 aataaatcca taaattcaga ttcttttagg gttataagcc gaaaaataaa taaaagaaat
    19381 atgactgaat ccgatttatt accaaataaa gaaagtacct ttaccccaat aattaataaa
    19441 aaatggaaat aaccgattta aaacaaatga caaaggaaga agtttttaat ttcatcagac
    19501 aacgcctttc tttcagtaaa gaactgcaag aacaattcag acatgtgaat aaagacgatc
    19561 tcgcaaaaga acatcgcaga ttcgaaatgt ccggaaatga atcaaagaca ggccaatgca
    19621 cgattttcaa cacagcgatt ctgaacgagt ttgccgatct tggcatctat gattatactt
    19681 cttacctttt tctcgacttc cacaatggca ctccaaccgt ttatctcaaa tatttctccg
    19741 aaaatgaaaa tttggaatat acatttaccg gatataccac aacggaaatc atctttgcaa
    19801 ttcttgaact gactatcttc tccggaaagc ccaaaagaaa tcgcagctaa aaaaaagaat
    19861 tgcacggaaa gacaatgcga ggtcaaaaga cttttatggc tttcatttag gcacggatta
    19921 cacggatttc acggttccat tagactaaaa gccgcgaaat ccgtgtaatc cgtacctaaa
    19981 taatatcaat ctaatagatg gtttcacttt tggctccctc ctttttatca tcacattata
    20041 tttgccaccc gtatagcata tttaccatct ttataccata ctctctattc tcataccata
    20101 tttcctgcat ttatttcctc ttttccatcc tattccgaaa aaaacatata tctttgtcac
    20161 acgctttctg cccatcagcg tgatgaaaca ggcaaaagcg gtttttattc cttaatggag
    20221 taaataacgt attgtctctc aaacttaaaa attagcagtt ttttcacacc gagagatgat
    20281 acaacagata ctccacgtag atagtcgtat atcaacatat cgattagaga tttgttatat
    20341 ataaacgttt ggcgtgggtg tctgttgttt atcattatct ggtgaagggt attgctaagc
    20401 cttaagttta gataatggta caacagcact cacgctttta ttgtatccgg tcggtttcaa
    20461 caatccttat accccaacca attccccacc cgaccgaaat cataaaaatc gtgggtgttc
    20521 gttgcacctc tccggacaat acattattta ctcctttttt tataacacat taaaacaaaa
    20581 gcaatatgcc aaaatggatt agtgtagaaa aagcagtgat taagtatcac atcgaaaaag
    20641 aagcgatcct gctttgggtg gaaatgggac aatttcctat gttatacata gacaatgttc
    20701 cgaacgttga cgaagaatgt attctggaac tctttcgccg aagtaaagcc ggcattacag
    20761 cagaatatat tgatacactg gaacaactgt gcatagataa aacaatggtc tgcgagaaat
    20821 acgcccacat tattcaattg aaagaaaagg aaattcagct gcagaaggaa ataaatacgt
    20881 tgataaacga aatacaggca gcaatgaaga gacaaaatga acggatccgg gatttgaaaa
    20941 aagcgattgg agagaataac aacgttatac gtagtgacag ttggataaaa aggctgcgca
    21001 aaaggtttca atggtgaata attatcagcg taccaattac catgtgggac acaacgtaaa
    21061 caattagcat attggcacat tattgcacgg tttttaccac agaggacaca gaggtgaatt
    21121 tggtttatga cttacgcttg tgaccctaat tttgatgcgt aatcctcctc tataaagttg
    21181 aaaaaacatg aaaacatctg ccacctgcaa ccaaacgcgt gtaatgcact agttgataaa
    21241 tagttagagc gttgcagata cctgcggcag ataggttgca gataaagtat ctgcaacaca
    21301 gtataaacct tacataagct aattctccag gagggcaaaa gtttattgta tacataaact
    21361 tcccgtttcc aggcgaggga actgtcgttt ccggcattag aaattacaat ttccacggca
    21421 ggaaacgaaa gtttctaaga cgggacacta cagtttccac gtaaggatac tgtcgtttcc
    21481 ccgtagagac accaccattt ctccatagag tcaccccaat tatcccatag ctttgcacaa
    21541 aggaatcaag gctttttctt tgattatata acgtgttgca gatactttat ctgcaaccta
    21601 tctgccacag gtatctgcaa cgttccaact atttattaac tagtgtatta cacgcttttc
    21661 gttgcaggtg gcagatgttt ttatgttttt caactttata gtaggaaaaa atttcattca
    21721 tttctgcacc gtttcattca tttttgcact gaaatgagca aaatagtgcg attttagttt
    21781 atttctgcac acttctttgc taaatgggaa tttatatttc actacagagg acacggagga
    21841 cacagaggtt aactattttt tattcactat agagtaatac agagtaatcg tatttatcgc
    21901 tctgttttgc ttacggaaag agagagaaga actctgtgtc ctctgtggtg aactcgtaaa
    21961 gttcccgttt tttttgtgtt ccatataaag gttaagaggc aggatatgaa aagacaggaa
    22021 tgttgaacat aaataaacag gagttgtttt agtatattat tcgctattta tcaacgcaaa
    22081 acctctaaac atcaacgtgg tatatgaaaa agaattttgg attcgtcctg gcggctgcaa
    22141 tcttgcttgc tggctgcgga cagaaaaaag aaacgacaac gacaactgca cgtcccgtaa
    22201 agactacgat tgtcgagtca agatcgatta tcagaaaaga tttctcggga atcgtggaag
    22261 cggtggaata tgtgaagctg gctttccgag tcaacggaca aatcatccag cttcctgtca
    22321 tcgaaggaca gaaagtgaaa aaaggacaac tcatcgcggc tatcgacccc agagacattg
    22381 cgttgcaata tgccgctacg aaatcggcat acgaaacggc ttcggcacaa gtggaacgta
    22441 acaaacggct cctctcccgg caagcgatct ccgtgcagga atatgaaatc agcctcgcca
    22501 acttccagaa ggcgaaatct gaatacgaac tgtctgccaa caatatgcgc gacaccaagc
    22561 tgacagctcc tttcgacggt tctatcgaaa aacgactggt ggaaaactat cagcgtgtca
    22621 actccggtga ggggatcgtg cagcttgtca atacacacaa tctgcgtatc aaattcacca
    22681 ttccggatgc gtatctttat ttgttgcgtg ccaaagaccc gcgtttcctt gtagagttcg
    22741 acacatttaa aggacacgtg tttcaagcga aactggaaga atatcttgat atttctacgg
    22801 atggcacagg aattccggtc agcatcacga ttgacgatcc gtcattcgac cgcgatctgt
    22861 atgctgtgaa acccggtttc acgtgcagca tccgtttcac ggcagatgta ggtccgttgg
    22921 tgcaggatag ctggacgatc gtaccgctta gtgccgtatt cggtgaaagc gaagggaata
    22981 aaatgtatgt ctgggtggta gaagacaaca aagtccacaa acgggaagtg accgtcaacg
    23041 ccccgaccgg agaagcacag gcgctcatct cggaaggttt gaaacccggt gaaaaaatcg
    23101 tcatagcagg cgtataccaa ctagtagaag gagaatctat cacaactgtt gacaggtgat
    23161 agttggtaaa tgattaagta tcatttatcc gctgtcattc atcaattatc aacgatcatt
    23221 tattatgagt ttagccaaat attcattaga taatacgaaa atcatctatt tctttcttgc
    23281 tgtattgctg attgggggaa tcacttcctt cggcaagctg ggtaagaaag aggatgctcc
    23341 tttcgtcata aagtcggcgg ttattatgac ccgctatccg ggtgccgaac cggcagaagt
    23401 ggagcggttg attaccgagc ctatctctcg tgaaattcaa agtatgagcg gtgtgtacaa
    23461 gataaaatca gaatcgatgt acgggctctc aaaaatcaca ttcgagttgc aaccttcctt
    23521 gtcggcaagc tccattccgc agaagtggga tgagttgcga cggaaggtgc taaatataca
    23581 gccacaattg ccgagcggtg cttccgcacc gacggtttcc gatgatttcg gcgacgtgtt
    23641 cggtatctat tacggtttga cggcggacga cggttacaca tacgaagaga tgcgcaactg
    23701 ggcggaacgg atcaagacgc aggtagtgac ggcagacggg gtgatgaaag tcgccctgtt
    23761 cgggacgcag acggaggtgg tcaatatttt tatttccacc aataagctcg taggtatggg
    23821 catcgacccg aaacagcttg ccagtctgtt gcaatcgcag aaccagatta tcaataccgg
    23881 agaaatccgt gccggcgagc aacagctccg ggtgaccgcc aacggtatgt ataccaccgt
    23941 agacgatatc cgcaaccaag tgattaccac caaagccgga caggtgaaac tgggcgatat
    24001 cgccgtcatc gaaaaagggt acatggatcc ctccatccaa tatcatgcac gtgaacggca
    24061 aacgtgccat cggcatcggc gtctccaccg acccgcaacg ggacgtggtg caaacgggca
    24121 agaacgtgaa agccaaactg gacgaattgt tgccactgat gcctgtggga ctggaactgc
    24181 aaagcctgta tctggagaac gaaattgcca acgaagccaa caacggattt atcatcaatc
    24241 tgatcgaatc gattctgatt gtaattgtga ttatcatgtt ggtgatgggt ttgcgcgcag
    24301 gtgtgctgat cggctcgtca ctgattttct ctattggcgg cacattactt atcatgtctt
    24361 tcttcggtgt cggactgaac cgtacatcat tggcgggatt tatcatcgcc atggggatgc
    24421 tggtggataa cgccatcgtg gtaacggaca atgcacagat tgccatcgcc cgcggagtag
    24481 accggcggaa agcgctgata gacggcgcaa cctatccgca atggggattg cttggggcta
    24541 cgttcatcgc ta
//
