LOCUS       c00004_gnlPro..        24710 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OHHPFMCJ_4.
ACCESSION   c00004_gnlPro..
VERSION     c00004_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 11:38:51
            Original ID  :: gnl|Prokka|OHHPFMCJ_4
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 3877689
            Orig. end    :: 3902399
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24710
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[3887689:3892399]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14710
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..24710
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24710
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_fatty_acids"
                     /region_number="3"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             633..1007
                     /locus_tag="ctg4_4405"
                     /transl_table=11
                     /translation="MEKSILTFNDLPEVVAQLRDEVMSLKSLLAEQRSVNNAKTVDTHV
                     PMSVDEAAEYLGIPKGTLYMKLSEGTIPATKPGKRYCLYRDELDKWLETARKNPIPLSD
                     EELNKSLSSSHRRKPNPRNW"
     CDS             1013..2110
                     /locus_tag="ctg4_4406"
                     /transl_table=11
                     /translation="MEEDKNYINLIRGDLTKASQAHNGMPDSVGMMNIKTANQTILEAS
                     LLPTPRALWDSFWYEGELSCLFADSNVGKSILAVQIADRIARTDNVLYLDFELSEKQFQ
                     LRYTNEHGELYTFPDKIYRVSIDCNQLLDANFEEAIIGGIEQMAVQTDCKIFIIDNLTY
                     LCCAMEKGDAAGRLMIQLNNLKKRYALSILVLAHTPKRSLDCPITSNDLAGSKRLYNFF
                     DSVFTIGKSAQDGGLRYVKQLKVRYGTFSHDADNVIVYEIDKVDAFLQFVFRGYSTEKE
                     HLKKLGDNESSQRDCQILQLSQSGKSVREIASQVNCGKSTVNRIIQRSKESKNAGVPSV
                     PLSQPLECGTMGQDGTADNQPSKTD"
     CDS             2114..3229
                     /locus_tag="ctg4_4407"
                     /transl_table=11
                     /translation="MGNYSLQKYKGTATRHTCPKCGDRHSFVYYVDENNVPLHPSVGRC
                     NHESGCGYHYTPKEYFQEHPEHRTTNDFSFDRQRAEQKKVKQQSKPTAIGYIPPHYVEK
                     SQSERSNFFRFLFTLLTSYYGDKAKEVLKRLLEEYRLGATRDGSVIFWQIDRTGKVRTG
                     KVMQYNPEDGHRIKGGQTSAVNWIHSILKKQRVLAEDWQLSQCLFGEHLLKTHPDKVVV
                     LVESEKSAVIGSAIFPDYVWLATGGKSQMREEKLRVLSGRTVLLFPDADAYAEWKQRAE
                     SMYFCKVVVSDIIERNATPKQKEAHIDIADWIIFQIREGKVMSTANHLVEAERILQRMI
                     EKNPVLQKLIDDLDLVLVGASPIGNDDEKPP"
     CDS             3513..4916
                     /locus_tag="ctg4_4408"
                     /transl_table=11
                     /translation="MATKSSIHIKPCNIASSEAHNRRTAEYMRHIGESRTYVVPELSTD
                     NEQWINPDFGSPDLRMHYDNIRQMVKEKTGRAMQEKERERKGKNGKIVKIAGCSPIREG
                     VLLVRSDTTLADVRKFGEECQRRWGITPLQIFLHKDEGHWLNGQPEAEDRESFKVGDRW
                     FKPNYHAHIVFDWMNHETGKSRKLNDDDMMQMQTLASDILLMERGQSKAVTGKEHLERN
                     DFIIEKQKAELQRMDAAKRHKEEQINLAEQELKQVKSEIRTDKLKKTATTAATAITSGV
                     ASLFGSGKLKELERANEKLQDEVSKRNTNIEKLQSQVQQMQKQHDTQIHNLREMHRQEL
                     DMKEKELSRLARIIDKAFRWFPMFREMLRMEKFCAMLGFSKEMTESLIVKKEALKCSGK
                     IYSEQHRRNFDIKDDILRVENDPDDESRLNLTINRKPIADWFREQWHRLRYGARVPQQE
                     ERKSRGFKL"
     CDS             complement(5009..5512)
                     /gene_functions="resistance (resist) CfxA (Score: 381.4;
                     E-value: 1.8e-116)"
                     /gene_kind="resistance"
                     /locus_tag="ctg4_4409"
                     /transl_table=11
                     /translation="MFKDMVNVAQTDSFIATFIPRSSFQIAYTEEEMSADHNKAYSNYT
                     SPLGAAMLMNRLFTEGLIDDEKQSFIKNTLKECKTGVDRIAAPLLDKEGVVIAHKTGSG
                     YVNENGVLAAHNDVAYICLPNNISYTLAVFVKDFKGNESQASQYVAHISAVVYSLLMQT
                     SVKS"
     CDS             complement(5532..5975)
                     /gene_functions="resistance (resist) CfxA (Score: 291.8;
                     E-value: 3.5e-89)"
                     /gene_kind="resistance"
                     /locus_tag="ctg4_4410"
                     /transl_table=11
                     /translation="MEKNRKKQIVVLSIALVCIFILVFSLFHKSATKDSANPPLTNVLT
                     DSISQIVSACPGEIGVAVIVNNRDTVKVNNKSVYPMMSVFKVHQALALCNDFDNKGISL
                     DTLVNINRDKLDPKTWSPMLKDYSGTSHIIDSERFAALYSYSE"
     CDS             6148..7593
                     /locus_tag="ctg4_4411"
                     /transl_table=11
                     /translation="MEAIIEKISELSKLLSVKTRMSDDLFHLFGKFGIGHLLSRLSLEK
                     QDGVSASELLLSLCLFRIVGESIHSICKHKIYELSNHGKNCFYRMMIRPQMDWRRLMNH
                     FALRYMCLLRKYGEVPQSDTTTCFIIDDTVLEKSGVRMEGISRVFDHMKGRCVLGYKLL
                     LCAFFDGKTTIPFDFSLHQEKGKQGNCGLTRQQLKKAYHTKRNTGNPDYKRFQECKMSK
                     LEVAMDMLRRGWKMGLHAKYVITDSWFTCEQLMTCVRSIGKGAMHFVGLAKMGKTKYTI
                     SGKKKNAAELIATYERERGKNCRKYKCRYIQLNGNLGDIPIRIFLIKYGRNSAWNVLLT
                     TDTTMSFVKAFEVYQIRWNIEVMNKETKQYLGLGGYQGCDFNGQIADATLCYLTYTVMA
                     LEKRFTEYQTMGELFSDMEGDLMALTLWKRVLTCIERILRILGEILGMTPQYLMATISG
                     NDKEMSKILVMAEALEKWDEVCG"
     CDS             7584..7874
                     /locus_tag="ctg4_4412"
                     /transl_table=11
                     /translation="MWIVCITSVRHVLTVNGYGGRQTKENEKSWCFKGWETLVHNFTEK
                     YVSKIYKSGQPHQNVNNLIINTCRFCINRDKWGGYKDEKFQQFTISPLKNA"
     CDS             7914..8018
                     /locus_tag="ctg4_4413"
                     /transl_table=11
                     /translation="MFLKKYYPQGKFELYGAKNQFLWGSSFDLDQWFF"
     CDS             8881..9342
                     /locus_tag="ctg4_4414"
                     /transl_table=11
                     /translation="LEVYEEQEVSSELEPELISPEEQDELLDETDKESGEEEENKKIFQ
                     ELNHTVVQKQLYLSPELSREDLAQIVHLNNARFARMIRECTGTNFNGYINGLRINYAIK
                     LMKKYPNYTIRAIADESGFNSAPILYNLFKKKTGMTPYEFKKAQDTLRN"
     CDS             9496..9768
                     /locus_tag="ctg4_4415"
                     /transl_table=11
                     /translation="MKKEWLKYDYWAKDITPSPTLRKWFHEDIPGHWGDFVTQYQKELD
                     ASPSMADFLTLIKPHPVITLLYASKEPVYNHARILRDYLEMRLRE"
     CDS             10001..11083
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_4416"
                     /sec_met_domain="HBT (E-value: 1e-15, bitscore: 56.8,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPLTKMLELGNYGGFILSYNGCQIINAQNGEILFERRINPEMLPY
                     LEKKARKNGFALFTYHDDTIITDSPENEHIQNEARLNDLQIIKEEEFSAAVDFAPCKCM
                     LVSDDEEALLGLEDHWKRRLNGALDVFRSEPYFLEVVPCAIDKANSLGALLEVLGMKRE
                     EVIAVGDGVCDVTMIQLAGLGIAMGHSQDSVKACADYVTASNEEDGVVVAVEKAIISEV
                     RVAEIPLDQLNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLAL
                     AETVAGLGSMILCQPDEIVVGMQVSGNHISSAHEGDTVRAVGTVVHKGRSSHVWNVDVF
                     TSTNKLVSSIRVVNSVMKKR"
     CDS             11080..12117
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_4417"
                     /sec_met_domain="Chorismate_bind (E-value: 8.4e-48,
                     bitscore: 162.1, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDEEISNLTTIDAFIQRKQPFAVYRIPGEKVPRLLTQAEGAVRL
                     IYDLKELNGQRGFVIAPFQVSETCPVVLIQPDQWGQPLPIDNDTAEEREVALRMQRQES
                     FLTSSTEEYASCFHTFINALRERTFDKLVLSRHLTVDKVADFSPLSIFRAACKRYIHSY
                     IYLCYTPQTGIWLGSTPEIILSGEKDEWHTVALYGTQPLQDGRLPQVWDEKNRKEQDYV
                     ASYIRRQLLSLDIHSTENGLYPAYAGALSHLKTDFRFSLKDNKGLGDLLKVLHPTPAVC
                     GLPKEEAYQFILQNEGYDRRYYSGFIGWLDPEGRTDIYVNLRCMHIEDKQLTLYAGGGL
                     FTLRN"
     CDS             12214..12807
                     /locus_tag="ctg4_4418"
                     /transl_table=11
                     /translation="MYTDKKNILQLVALLEAHGITKVVLCPGSRNTPIVHTLSNHPNFT
                     CYAVTDERSAGYFAIGLALNGGKPAAVCCTSGTALLNLHPAVAEAFYQNVPLVVISADR
                     PAAWIGQMDGQTVPQPGVFQTLVKKSVNLPEIHTEEDEWYCNRLVNEALLETNHHGKEY
                     GAYQCSYFRTTVSVHCRYAPGSACDNPLSGIERL"
     CDS             12767..13882
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_4419"
                     /sec_met_domain="TPP_enzyme_C (E-value: 5.7e-05, bitscore:
                     21.8, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VRVITRYQGLNVYDRDYNDLVDRMNKYQKRMIIIGQMNLIYLFEK
                     RYIKLLYKHFAWLTEHIGNQTVPGIPVKNFDAALYAMPEEKVGQMVPELLITYGGHVVS
                     KRLKKFLRQHPPKEHWHVSPDGEVIDLYGSLTTVIEMDPFEFLEKIASLLDNRTPEYPR
                     VWENYCKIIPEPEFAYSEMSAVGTLLKALPESCALHLANSSVVRYAQLYSIPSTIEVCC
                     NRGTNGIEGSLSTAVGYAAASDKLNFIAIGDLSFFYDMNALWNVNVRSNLRILLLNNGG
                     GEIFHTLPGLDMSGTSHKFIAAVHKTSTKGWAEERGFLYLQAQNDEELAEAMKTFTQPE
                     TMEQPVLLEVFTNKNKDARMLKNYYHQLKQK"
     CDS             13886..14710
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg4_4420"
                     /sec_met_domain="ECH_1 (E-value: 7.5e-80, bitscore: 266.7,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYDDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKQYPKFP"
     CDS             14771..15796
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_4421"
                     /sec_met_domain="MR_MLE_C (E-value: 4.6e-27, bitscore:
                     93.9, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRLLHFKRPAGTSRGTYTTRKVWYLHFASPDFPGRVG
                     IGECAPLPALSCDDLPDYEDILIRTCRQVEEEQGKLDKDGLCKYPSILFGLETAIWHFF
                     AGSWALSDTAFSRGEVGIQINGLIWMGDFDHMLSQIEKKMEAGFRCVKLKIGAIDFEKE
                     LALLRHIRTHFSSKEIELRVDANGAFSPGDAMEKLKRLSEFDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGCNMLEEKKKLLATIRPQYIIIKPSLHGGICGGDEWIMEAEK
                     QHIGWWITSALESNIGLNAIAHWCATFNNPLPQGLGTGMLFTDNIEVPLEIRKDCLWFC
                     K"
     CDS             15828..16610
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 57.9; E-value:
                     2.3e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_4422"
                     /sec_met_domain="AMP-binding (E-value: 3e-16, bitscore:
                     57.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFDRQQQRLLLEGKEYTFEDISQLIAGGAEAHSSAYWDLYLFLN
                     EWFNDSPVITVHTSGSTGIPKELMVRKDQMMQSARLTCEFLNLKKGESALLCMNLRYIG
                     AMMVVVRSLVAGLNLIVRPASGHPLADIKESLRFVAMVPLQVYNTMQVPEEKERLKQTD
                     ILIIGGGAVDEALETEINHLPTAVYSTYGMTETLSHIALRRLNGASASEHYYPFPSVKL
                     SLSAENTLIIDAPLVCDETLQTNDIARIYPDGSFMILE"
     CDS             16621..16944
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg4_4423"
                     /sec_met_domain="AMP-binding_C (E-value: 1.8e-05, bitscore:
                     24.5, seeds: 272, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VINSGGIKIQAEEMEKLLRPFIPVSFVITSVPDQRLGQAVTLLLA
                     DQPDTEEIGNKLHEILEPYYRPKHILTIESIPQTENGKINRAECRILAKQMLMTFYPHT
                     LTP"
     CDS             complement(17317..17880)
                     /locus_tag="ctg4_4424"
                     /transl_table=11
                     /translation="MKISFSKQTKERAFKQLYEEYYAPFCLYAKRFVDDKETREDIVSD
                     VFTSLWDKLDTDSFDLQSNTALAYIKMCVKNSCLNFLKHQEYEWSYAENIQKKAPVYET
                     EPDSIYTLDELYRMLYETLNKLPENYRTVFIKSFFEGKTHTEIAEEMNLSVKSINRYKQ
                     KTMELLRNELKEYMPLLLLLFLRA"
     CDS             18054..20045
                     /locus_tag="ctg4_4425"
                     /transl_table=11
                     /translation="MKNKFFLLAITFCLPIHSQGVSKSFIPMAEIPAGSFYMGSDGLGE
                     DFDEAPIHQVIISRPFRMGITEITNAQYESFRPEHRALRGKNGVSLEDDEAVVNVSYSD
                     AVAFCEWLSRKEGKNYRLPTEAEWEYACRAGTYTLFSTGDGLPAVYHRNQKVVRDFDPV
                     SLKVAQTPPNTFGLYDMHGNVEEWCLDWYAPYSAEKQKDPAGPLTGEFRVTRGGSHHTP
                     EKYLRSANRLAMLPEDKHSQTGFRIVEADTRLNVSGTSAPVPFNQKSVENTSIKWKKVS
                     AITPMFLPPIPFVVRPVCDSNTPFYLHNHQPAVTWCDNGDLLAIWFSANEENGRGMVVL
                     GSRLRAGHTDWDVASLFFKVPDRNMTGSALLNDGKGKLYHINGVEASGDWQNLAMVLRT
                     STDNGASWSTPKLIAPEHTKRHQVIAGTIRTREGWLVQACDAGPGSHDGAAVQISKDGG
                     KTWCDPWDGAPLPDFKEGGTGSTIAGIHAGIVQLGNGSLMAMGRGNSIRNKEGKLRMPM
                     SISDDMGKTWKYVASELPPIDGGQRLVLMRLNEGPLLLVSFTDHPQRTPLEERGLEFKD
                     KNGNVKKGYGMYAALSYDEGKTCTVRKLLTDGEYRFLNGGAWTGYFEMDENHAEPRGYL
                     AGTQTPDNVVHILSSRLHYRFNLAWLEK"
     CDS             20149..21060
                     /locus_tag="ctg4_4426"
                     /transl_table=11
                     /translation="MSPESLLRKAQALGDDIKEMESIDVLGAYYQAQTKIKTNRRKNMY
                     NQLMRYAAFLTIPLFLSSLVLGYLYFSGTETDEKYAEVVTATGSVIRYELPDHSVVWLN
                     AGSTLRYPTTFKKDNRLVELKGEAYFEVQADKDRPFYVNTPNGLSVYVYGTKFNVAAYE
                     DDNYIETVLEKGKVNVITPDQETIVLAPGEQLLYDKQSQKSKKNKVDVYGKIAWKDGKL
                     IFRNASLEEILKRLERHFNVEIQFNNRSGKEYKYRATFRTETLSQILDYLTRSADLKWK
                     IEEPQQQADDTLSKTKIRVDLY"
     CDS             complement(21072..21212)
                     /locus_tag="ctg4_4427"
                     /transl_table=11
                     /translation="MNYGLIPASVCETLYRESGKFGGRQLLVAAFFLSFILLCYSMVFL
                     F"
     CDS             21313..22329
                     /locus_tag="ctg4_4428"
                     /transl_table=11
                     /translation="MRISLALLFAVVLQLSAEDGYAQRTRVAISMNNVSVEQVLNKIEE
                     TSDYVFLYNDKTIQKNRIVSVRNNSGKILDILDEVFKGTNITYTVVDKQIILSTNKLNV
                     TEQDPTIQVKGTVKDTKGEPLIGVNVKVKGTTTGAITDFDGNFQIQAKKGAVLEISYIG
                     YASQEVKVTDNKSLSIVMTEDAKVLNEVVVTALGIKRETKSLTYNVQQIGGDEVAKAKD
                     MNVMSSLAGKVAGVNINASSSGIGGGARVVMRGTKSISGNNNALYVVDGVPLANISGEQ
                     PDDQYTGAGQSGDGLANFNADDIESISVLSGSYRRCTIRFGCCQWCGTYHNEERSCR"
     CDS             22337..22981
                     /locus_tag="ctg4_4429"
                     /transl_table=11
                     /translation="LTYSNNSTFYSPFRLPEFQNTYGSETGEWYSWASKLSSPTDYEVK
                     DFFQTGYNVANTVSLTTGTQKNQTYVSVGAVNARGIIQNNDLDRYNFSVRNTTSMLNDK
                     LTMDLSFMYSNVKEQNMLSQGEYANPLVPVYLFPRGDDFSKYQYYERYDVDRNIKTQFW
                     SIERKWIIHAESLLDYEPEYVYQQERPFSGKRFTKIYDNRLVECFRTRETG"
     CDS             22950..23828
                     /locus_tag="ctg4_4430"
                     /transl_table=11
                     /translation="LNVSGRVKLDKETINSEKKMYASTLNVIAENSDKGAYVQSNKNTS
                     QIYADAMLNINKYFYHDTWNLTASLGASLLDLDYKELNFGGGLLTIPNLFTSNNANVSG
                     KLTYKNTNYHDRTNSLFGTFSLGYKGMVYVDGSLRNDWISALAGTNHSSILYPSIGASA
                     ILTNMFTMKSNILSYAKVRLSYSEVGNAPERFRAITTYAVLGGLNTTSYFPIKDLKPER
                     THSWEGGFNLGLFDNKLTLDVTAYKTYTENQLFSPEISTTTGYSKLYVNAGKVTNKGIE
                     LALGFKQNIDL"
     CDS             23906..24607
                     /locus_tag="ctg4_4431"
                     /transl_table=11
                     /translation="LGVTVHLDEMDVYSLGGAKQRLTVGGSMGDVYVNTMRTDEHGHIW
                     MNSMTGTLETDKNNYVYAGNTNPKYTLSWRNEFNWKGISLGFMLNARVGGIGVSATQAV
                     MDYYGVSKTSAEARDNGGVKVNYQMIDAQTWYQTIGANGTGYVGSMYVYSMTNVRLGEL
                     TLGYDIPINKWCKWISGLNVSFVGRNLWMLYCKAPFDPESTASTGTYNQGMDYFMQPSL
                     RSMGFSAKISF"
ORIGIN
        1 caattacgca agcagagagc aacgggaaaa ggaagagcgc atccgcatgg tcatggagta
       61 ttgccattat tacctgcctc gcattgccga ccaagaaacc gtgaaccaca tctgtactga
      121 ggtggacaaa tggatgaatc ttaacactta taccccgaag cccatacaaa gaccgtttac
      181 caaagacatc aacaacattc cactccgtca cttcgtatgg aatatctctg agcgtttcct
      241 gtacaagaga tactacaatg gggataaccg tgccaagttc atcaaagccc ttttcccgaa
      301 atcgtttgct gatacagact tatcaaccat caagaatttc aaggtagagc cgttaaagac
      361 ggaaattccc attgatgaac ccgaaaacgg caaacttgat ttccactatc ccgaggatta
      421 tgtgcggaat taggataatc acgacaccaa cgacaaccat ccggtaactc ataaccgcct
      481 gttttacatc gtttcccgag taattttacc cgtcatttat ggctgggctt aattattcgg
      541 gaattatttt gcaatgacgt gtcgtggaga tattcacgga tatatcattt cagtcctttg
      601 cgccaagtct tacaaaagag acgagtacgc gaatggaaaa atcaattctt accttcaacg
      661 acctccccga ggttgtcgct cagcttcgag acgaagtgat gagcctgaaa agcctgctcg
      721 ccgagcagcg cagtgtgaac aatgccaaaa cggtggacac ccacgtgccc atgtctgtgg
      781 acgaggcagc agagtattta ggtatcccta agggtacgct ctacatgaaa ctgtcagaag
      841 ggacaatccc tgccaccaag cccggcaaac gctattgcct ttaccgtgac gaactggaca
      901 agtggctgga aaccgcccga aagaatccca taccgttgtc agacgaggaa ctgaacaagt
      961 ccttatcctc ttcccaccgt cgcaagccca acccacgtaa ctggtgaatg atatggaaga
     1021 ggataagaac tatatcaacc tgatacgtgg cgacctcaca aaagcatccc aagcgcataa
     1081 cggtatgccc gacagtgtag gcatgatgaa tatcaagacg gcaaaccaaa ccattcttga
     1141 agcatcgtta ttgcctacgc cccgtgcgct gtgggacagc ttttggtacg agggggaact
     1201 ctcctgcttg tttgccgatt ccaacgtggg caagtccatc cttgccgtgc agatagccga
     1261 ccgcatcgcc cgaaccgaca atgtgctgta tctggacttt gaactgtccg aaaagcagtt
     1321 ccagctccgc tataccaacg agcatggaga gctctacacc tttcccgaca aaatctatcg
     1381 ggtgtctatt gactgcaacc agcttttgga tgccaacttt gaggaagcta tcataggcgg
     1441 cattgaacag atggctgtgc agaccgactg caagattttc atcattgaca atcttaccta
     1501 cctgtgttgc gccatggaga aaggcgatgc cgcaggacgg ctgatgattc agctgaacaa
     1561 tctcaaaaag agatatgcgc tctctatcct tgtcctggca catacgccca aacgctcttt
     1621 ggattgtccc atcacatcca acgaccttgc cggaagcaaa cggctctaca atttctttga
     1681 cagcgtgttc accattggaa aaagtgccca agacggaggg cttcgctatg tgaagcagct
     1741 taaagtgcgc tatggcacgt tctctcatga tgcggataat gtaatcgttt acgagattga
     1801 caaggtggat gctttcttgc agttcgtgtt caggggctat tccacggaaa aggaacactt
     1861 gaaaaaattg ggcgacaatg aatcaagcca aagggattgc caaattctgc aactctccca
     1921 atcgggcaag tccgtcaggg agatagcctc acaggtgaat tgtggcaagt ccaccgtaaa
     1981 ccgtatcatc cagcgcagca aagagagtaa aaacgcaggt gtcccaagtg tcccactgtc
     2041 ccaaccctta gagtgtggga caatgggaca ggatgggaca gccgacaatc aaccatcaaa
     2101 aacggactaa gctatgggca attattcatt acagaagtat aaaggaacgg caacacggca
     2161 tacctgcccc aaatgcggag acaggcattc tttcgtctat tacgtggacg aaaataatgt
     2221 gccgttgcat ccatcggtcg gcagatgtaa ccacgaaagc ggttgtgggt atcactacac
     2281 tccgaaagag tattttcaag agcatcctga acacagaact accaatgatt tctcttttga
     2341 caggcaaaga gcagagcaga agaaagtgaa gcagcaaagt aagccgacag ccatcggcta
     2401 tattccccct cactatgtgg agaagtcgca aagcgagcgt agcaatttct tccgtttcct
     2461 cttcacactc cttacttcct actatggcga caaggcgaaa gaggtgttga agcggttgtt
     2521 ggaggaatac cgtttggggg ctacccgtga cggctctgtt atcttttggc agatagacag
     2581 gacgggcaag gtacgcacgg gaaaggtgat gcagtacaat cccgaagacg gacaccgtat
     2641 caagggagga cagacatcgg cagtgaactg gatacacagc atattgaaaa agcagcgtgt
     2701 gttggcagag gattggcaac tatcccaatg ccttttcggg gaacacttgt tgaaaacgca
     2761 tcccgacaag gtggtggtct tggtggaatc cgagaagagt gccgttatcg gttctgctat
     2821 cttccccgat tatgtatggc tggctacggg tggtaagagt cagatgagag aagagaaact
     2881 ccgtgtactg tcagggcgaa ccgtgcttct ctttcccgat gccgatgctt atgccgagtg
     2941 gaaacagcga gccgagagca tgtacttttg taaggtggtg gtttcggaca tcatcgaaag
     3001 gaatgccacc ccgaaacaaa aagaagccca tatcgacata gccgattgga ttatctttca
     3061 gatacgggag ggcaaggtga tgagtacagc caaccacttg gtcgaggctg agagaatcct
     3121 ccagcggatg atagagaaga atcccgtcct gcaaaaactg atagacgatt tagaccttgt
     3181 gctggtcggt gcatctccaa tcggcaacga tgatgaaaaa cctccctgac ggaggagagc
     3241 ggaagccgta ggctggagtt tgcagacaat ggcttgccat tgatatagcc cactataact
     3301 acacgctccg cttacgtagt tgtgggctct cccgagggga ttagggtttt accctaatga
     3361 cccactcagg gcgtttctcc cctgagaacc cagagcaaag agtgaccctc tctttgcaat
     3421 ctccgcttat gggttgcacc cctaagaacc ccatgcgttt acggacagcg gaaaagcaaa
     3481 caataaagta caaacccaaa aaacaagtat ctatggcaac aaaatcaagc atacatatca
     3541 agccctgcaa tatcgcatcg agtgaggctc acaacaggag gactgccgaa tacatgcgcc
     3601 acatcggaga gtccagaacc tatgtggttc cagaactctc caccgataat gagcagtgga
     3661 taaatcccga cttcggcagt ccggatttgc ggatgcatta tgacaatatc agacagatgg
     3721 taaaggaaaa gaccggacgt gccatgcagg aaaaggagcg tgaacgcaaa ggcaagaacg
     3781 gtaaaatagt caagattgcg ggatgctccc ccatacgtga aggagtgctg cttgtcaggt
     3841 cggacaccac actggcagac gtgcgtaaat tcggtgagga gtgtcaaaga cgctggggaa
     3901 tcacaccgct gcaaatcttc ctgcacaagg atgaagggca ttggctgaac ggtcagccgg
     3961 aagcggaaga cagggaaagc ttcaaagtcg gggacagatg gttcaagccg aactatcatg
     4021 cccatatcgt tttcgactgg atgaaccacg aaacaggaaa gagccgaaag ctcaatgacg
     4081 atgacatgat gcagatgcag acccttgcat ccgacatcct gctgatggaa cgcgggcagt
     4141 caaaggctgt cactggtaag gagcatctgg aacggaacga ctttatcatt gagaagcaga
     4201 aagctgaact gcaacgcatg gatgcagcca aacggcacaa agaagaacag ataaatcttg
     4261 ccgagcagga actgaaacag gtgaaatcag aaatacgcac tgacaagtta aagaagacag
     4321 ccaccacggc agcgacagcc ataactagtg gagttgcttc tcttttcggg agtggaaaac
     4381 tgaaagaact ggaacgtgcc aacgaaaaac tgcaagacga ggtttcaaaa cggaacacca
     4441 atattgaaaa attgcagagc caagtacagc agatgcagaa acagcatgat acgcaaatcc
     4501 acaatctcag agaaatgcac aggcaggaac ttgacatgaa agaaaaagaa ctgtcacggc
     4561 tcgccagaat catagacaag gctttcaggt ggtttccgat gttcagggaa atgctgcgca
     4621 tggaaaagtt ttgtgccatg ctgggattct ctaaagaaat gactgaaagt cttatagtca
     4681 aaaaagaagc cctgaaatgt agcggtaaaa tctattccga gcaacacagg cggaactttg
     4741 atataaagga tgatatttta agggtggaaa atgaccctga cgatgaaagc aggctgaacc
     4801 tgacaataaa caggaagccg attgccgact ggttcaggga gcaatggcac aggcttagat
     4861 atggagcaag agtgccgcaa caggaagaaa gaaaaagtag aggattcaaa ttataataga
     4921 agcaatttga ttagtaatct aaaagcactc cgataacgat tagagtgctt ttagattgtt
     4981 tatcattaat tatcaaagca agtgcagttt aagattttac tgaagtttgc attaataaag
     5041 aatatactac agctgatata tgcgcaacat attgtgacgc ttgtgattca tttcccttga
     5101 aatccttaac aaataccgct aaggtataac tgatattatt aggcagacat atataggcaa
     5161 catcattgtg agctgcaaga acaccatttt cattaacata acctgaacct gtcttatgcg
     5221 ctataacaac cccttcttta tcaagaagtg gagctgctat cctatctaca cctgttttgc
     5281 attcttttaa cgtattctta atgaaacttt gtttctcatc atcgataaga ccttcagtaa
     5341 acaaacgatt catcaacatt gcagcaccaa gaggagatgt atagttagag taagccttgt
     5401 tatggtcagc cgacatttcc tcttccgtat aagctatctg aaaacttgaa cgaggaatga
     5461 atgtggctat aaaactatct gtttgagcga cattaaccat atccttaaac ataaggttgc
     5521 ttgcattgtt gtcactctga gtaagagtat aacgcagcaa atctctcact gtcaatgata
     5581 tgactggtac ctgaataatc tttcagcata ggactccaag tctttgggtc aagtttatcc
     5641 ctatttatat ttactaaggt atcaagtgaa attcctttat tgtcaaagtc attacaaaga
     5701 gctaatgcct gatgaacctt aaacacactc atcataggat aaacactctt attattgacc
     5761 ttaaccgtat ctctgttatt aacaataacc gccacaccaa tttcgccagg acaagctgag
     5821 acaatttgag aaatgctatc agtcaaaaca tttgttaaag gaggatttgc gctatctttt
     5881 gtcgctgatt tatggaacaa tgaaaatacc aagatgaaaa tgcaaactaa agctatactc
     5941 aaaactacga tttgtttttt tctgtttttt tccatgttta tattatttat atttgtttga
     6001 cgagaatatc tttatttgcc gacaaaggta cataactaaa gtttcccacc caaataaata
     6061 gatagaaaaa taacagtttg tcgaattttc tttgtaaatt agtaatcgct aaagaactga
     6121 ttttaaagac aagacaacaa aactgttatg gaagcaataa tagagaaaat aagtgagtta
     6181 tccaaacttt tgagtgttaa aacccgaatg agtgatgatt tatttcatct ttttggcaag
     6241 tttggcatcg gtcacctatt atctcgcctt tcattggaga aacaggacgg agtttcggct
     6301 tcggagttgc tcctctctct ttgcctcttc cgcattgtgg gcgagagcat ccatagtata
     6361 tgcaaacata agatatatga gctttcaaat catggtaaga actgtttcta tcgcatgatg
     6421 attcgcccac agatggattg gagacgattg atgaaccact ttgcactgcg ttatatgtgc
     6481 ctattgcgta agtatggcga agttcctcaa tcagatacca ctacatgttt cattatagat
     6541 gacaccgtac ttgagaagag tggtgtgagg atggagggta tcagtcgtgt tttcgaccat
     6601 atgaaaggca gatgcgtatt gggctacaag ctgttacttt gtgccttctt tgacggcaag
     6661 acaactatac cctttgattt ttcactacat caagaaaagg ggaagcaagg caactgcggg
     6721 ctgacaagac agcaactcaa aaaggcatat cacaccaaga ggaacaccgg caatcctgat
     6781 tataagcgct ttcaagagtg taagatgtct aagctggaag ttgccatgga tatgcttcgc
     6841 cgtggatgga agatggggtt acatgcgaag tatgtgatta ccgatagttg gttcacctgc
     6901 gagcaactta tgacatgtgt tagaagcata ggtaaagggg caatgcactt tgttggactt
     6961 gcaaaaatgg gaaagacaaa atacactata tcgggcaaaa agaaaaatgc tgcagaactc
     7021 attgccacct atgaacgtga acgaggaaag aactgtcgta aatacaaatg tcgatatatt
     7081 cagctcaacg gcaacttagg agatatacct atcagaatct tcctcatcaa gtatggtaga
     7141 aactccgcat ggaacgttct gctcaccacg gatacaacga tgtctttcgt aaaagccttt
     7201 gaagtgtatc agattagatg gaacatagag gtgatgaaca aggagactaa gcaatatctc
     7261 ggattaggag gttatcaagg ttgtgacttt aatggtcaga tagccgacgc aacgctgtgt
     7321 taccttacat ataccgtcat ggctttggaa aagagattca cagaatatca aaccatgggc
     7381 gaactctttt cggatatgga gggtgatctc atggcactca cgttatggaa gcgagttctt
     7441 acctgcatcg aacgcattct tcgcatttta ggagaaatac ttggaatgac gccccaatac
     7501 cttatggcta caatcagcgg aaacgacaaa gagatgagca aaatccttgt aatggctgaa
     7561 gcgttggaaa aatgggacga agtatgtgga tagtctgcat aacttcagtt aggcatgtgt
     7621 taacagtcaa tggatatggg ggaagacaga caaaggaaaa tgagaaaagt tggtgtttta
     7681 aggggtggga aactttagta cataacttta cggaaaaata tgtttctaaa atatataaat
     7741 cagggcaacc gcatcaaaat gtcaataacc tgataatcaa tacttgtcga ttttgtatta
     7801 atagggataa gtggggtgga tacaaggatg agaagtttca acaatttaca atatcccccc
     7861 ttaaaaatgc ataattttgt atttgtctga ataatagcct gttgtcaaaa atcatgtttc
     7921 ttaaaaaata ttacccgcaa gggaaatttg aattatatgg ggcaaaaaat caatttttat
     7981 ggggtagtag tttcgatttg gaccaatggt ttttttagga aaatggacaa taagggagag
     8041 gaggaggttg aaaactacgt ttgtttccta agctaacgtt attttgatgc ggttgccctg
     8101 tatataaata gacagctggg gggaaaatgt ggggaaaaat tagataatta aaaaggctaa
     8161 atgactgaaa ataatcactt agccttttaa tccgtaccca gacccgtact tcgtaattgc
     8221 tgcgcccatc attcaagact gtcaaatcgg gtctttcctg tcaagccaat gatgcctatg
     8281 cgtatgccaa acacatggat tacggatttc tcgttccgtg aacaaacact ttatccgcaa
     8341 ctctgctatg tggtgtattg gcttaactcc atttctatgg gcaacacttt tgttgcagat
     8401 ttcaagcagc ttttatcgaa atacccatca gtaagaactc gtttattagg ctttcctcat
     8461 aattgggaac aagagccttt gtggagataa aataattgcc ctgtttctta aaaagcactg
     8521 gggcaaacca gctccgtctt taattgtttc caataaatgg attgtttcaa gcccctatag
     8581 aaagagaaca aaaattcctg tgtgaaaatt aatctacgac aaggagcaag caaggagcaa
     8641 tatcaaacaa aaatcaatac ctttgcagta catatgagat agaccaaaac aaaagtggaa
     8701 tatcggaaac gaatagcaag gaaaagagaa gaaacgaccc aagttgatgt cctttttgag
     8761 ttaataatca ataaaagcgt taaatcttca ccttttagaa tgtgcaatta aaaataacaa
     8821 ccatatttct gacttattat ctataaaata ttgagtaata atcggttgta aatacagtta
     8881 ttggaagtgt acgaggaaca ggaggtttca tcagaattgg aaccggaatt gatttctcct
     8941 gaagaacagg atgaactttt ggacgaaaca gacaaagaaa gtggggaaga agaggagaac
     9001 aagaaaatat tccaggaatt aaatcataca gtcgttcaaa aacagctata tctttctcca
     9061 gagctctcaa gagaagattt ggcgcagatt gtacatctga ataatgcacg ctttgcccgg
     9121 atgataagag aatgcaccgg aactaatttc aatgggtaca tcaacggact gcgcattaat
     9181 tatgcgatca agctaatgaa aaaatatcct aactatacca tacgtgccat cgctgatgaa
     9241 tccggattta atagtgcccc gatattatat aaccttttta agaaaaagac gggaatgact
     9301 ccttatgaat ttaaaaaagc gcaggacaca ttgaggaatt aaatagttct actaaacaat
     9361 tttcgttttt cccggtttat ctattgataa ctaaatatta atggaaatga tacaggtaag
     9421 gataaagagg gtttacgaag atttttcaga aacagatgga taccgggtgt tggtagataa
     9481 attatagtac gcggaatgaa gaaagaatgg ttgaaatacg attattgggc aaaagacata
     9541 acaccatccc ctacattacg taaatggttt catgaagata ttcccggaca ttggggagat
     9601 tttgtcacgc agtatcaaaa agagctggat gcttctccat caatggctga ttttctgact
     9661 cttatcaaac cacatccggt gataacacta ctttatgctt caaaagaacc ggtgtataat
     9721 cacgcccgaa ttcttcgcga ttatctggaa atgcgtttga gagagtgaaa ttaaagtaat
     9781 tttatctgtt tacgctttct gtcgttcact caatttccta cctttgtaat ctaaatcaaa
     9841 atcgtgtaat catgaagtat aaattattgg ttcttgatgt agacggaaca ctcctcaatg
     9901 atgcgaaaga aattagtaaa cgtacattgg ctgccctgtt gaaggttcag caaatgggag
     9961 tacgtattgt gctggcgtcc ggcagaccga cttatactca atgccgctta ccaagatgct
    10021 cgaacttgga aactatggag gttttatcct ttcctataat ggctgtcaga ttatcaatgc
    10081 acaaaacgga gaaattctgt ttgaacgtcg gattaatccc gaaatgttgc cgtatctgga
    10141 aaagaaagcc cgtaaaaacg gttttgcttt attcacttat catgatgata cgatcataac
    10201 ggattctcct gaaaatgaac atatccaaaa tgaagcccgg ttgaatgacc tgcaaataat
    10261 caaagaagaa gaattttctg ctgccgttga ttttgctcct tgtaagtgta tgctggtgag
    10321 cgatgacgaa gaagcattgc ttggtttgga agatcactgg aagagacgac tgaatggggc
    10381 gttggacgta ttccgttcgg agccctattt tctggaggta gttccctgcg ccatcgacaa
    10441 agccaattct ttgggtgctt tgctggaggt gctaggtatg aagcgtgagg aagtgattgc
    10501 tgtgggcgac ggtgtgtgtg acgtaacaat gattcaattg gcggggctgg gcatagctat
    10561 gggacattca caagactcgg tgaaagcctg tgccgattat gtgactgctt cgaatgagga
    10621 agacggagtg gtagttgcag tggagaaggc tatcatatcc gaagtgcgtg tagccgaaat
    10681 tccccttgac caactgaatg cgcaggcacg ccacgcattg atgggaaact tgggaattca
    10741 atatacctat gccgacgaag accgtgtgga agcaacaatg ccggtagacc atcgtacccg
    10801 tcagcctttt ggcattttgc atggcggggc tactcttgca ttggcggaaa cagttgccgg
    10861 actcggttca atgattcttt gccagccgga cgagattgta gtaggaatgc aggtcagtgg
    10921 aaaccacata tcttctgcac atgaaggaga tacagtgcgt gcagtaggaa cagttgtaca
    10981 taagggacgt tcctcccatg tatggaatgt agacgtgttt acttcaacaa acaaactagt
    11041 gtcttccata cgggtagtca acagtgtgat gaaaaagaga tgaccgacga agaaataagt
    11101 aatttgacaa ctattgatgc atttattcag cggaagcagc cgtttgctgt ttaccgtatt
    11161 cccggggaga aagttccccg tctgttgaca caggcggaag gagcggtacg tctgatatac
    11221 gacctgaaag aactgaatgg acagagagga tttgtcatcg ctccgtttca ggtgagtgag
    11281 acgtgtcctg tcgtattgat tcaacccgat cagtgggggc aacctttgcc gattgacaat
    11341 gatacggcag aagaacggga agtcgctttg cggatgcaaa gacaagaatc gttcctgact
    11401 tcttctacgg aggaatatgc ctcctgcttt cataccttta taaatgcatt gcgtgagagg
    11461 acgtttgata aactagtgct ttcccgtcat cttacagttg ataaagtagc ggatttttct
    11521 cctttgtcca tctttcgggc ggcttgtaaa cgttatattc attcgtatat atatttatgt
    11581 tatactccgc agacaggcat ctggctggga agtactcccg aaattatttt atcaggtgag
    11641 aaagacgaat ggcatacggt tgcgctgtac ggaacacagc ctttgcaaga tggcagactg
    11701 ccgcaagtat gggatgaaaa gaaccggaaa gaacaagatt atgttgcttc ttatatccgt
    11761 cggcagcttc tttcactgga tattcattct acggaaaacg ggctatatcc tgcttatgcc
    11821 ggtgctttgt cacatttaaa aactgatttc cgtttttctt tgaaagataa taaaggtttg
    11881 ggagaccttc tgaaagtttt gcatccgaca cctgccgtat gcggcttgcc gaaggaagaa
    11941 gcctatcagt ttattttgca gaacgaaggt tacgaccgcc gctattactc cggctttatc
    12001 ggatggctcg atccggaagg acgaacagac atctatgtaa acttacgctg tatgcatatc
    12061 gaagataaac aacttactct ttatgccggc ggtggattat ttactcttcg gaattgaatg
    12121 acgaatggct ggaaacggag aagaagttgc aaaccatcaa acggctgatt gcagtgcctc
    12181 ctttaaaatc ataaactact aataattatc atcatgtata cagacaagaa gaacatactc
    12241 cagttggttg cgttgctcga ggcgcatggg attactaagg ttgtgttgtg tccgggtagt
    12301 cgtaatacgc ccatagtaca tactttgtct aatcatccga acttcacctg ttatgcagtg
    12361 acggatgaac ggagtgccgg ttattttgcc attggtcttg cgttgaatgg tggtaagcct
    12421 gctgctgtgt gctgcacttc cggtactgca ttattaaatc ttcatccggc tgtagccgaa
    12481 gcattttatc agaatgttcc tttagttgtc atttcagcag accgtcccgc tgcctggatc
    12541 ggacagatgg atggacaaac agtgccgcaa ccaggtgtgt ttcaaacgct ggtaaagaag
    12601 tcggtcaatc ttccggagat tcatacggaa gaagatgaat ggtattgcaa tcgcctggtg
    12661 aatgaagctt tgctggagac gaatcatcat ggaaaagagt acggtgcata tcaatgttcc
    12721 tatttccgaa ccactgtttc agttcactgt agatacgctc ccggaagtgc gtgtgataac
    12781 ccgttatcag ggattgaacg tctatgaccg tgattataat gatctggtcg accggatgaa
    12841 taaatatcag aagcgcatga ttatcatcgg tcagatgaat cttatctatc tgtttgaaaa
    12901 aagatatatc aagttattat ataaacattt tgcctggttg acggaacata tcggcaatca
    12961 gacagttccc ggtattccgg taaagaattt cgatgcggca ctttatgcca tgcccgaaga
    13021 gaaggtcggt cagatggttc ccgaattgct gattacttat ggaggacatg tcgtttccaa
    13081 acgattgaag aagtttcttc gtcagcatcc gcctaaagaa cattggcacg tatcgccgga
    13141 cggtgaggtg atcgatttgt acggctcatt aactacggtg atcgaaatgg acccgttcga
    13201 gtttctggag aagatagcca gtttgctgga caatcggact cctgaatatc cccgtgtgtg
    13261 ggaaaactat tgcaagatca ttcccgaacc ggagtttgct tattcggaaa tgtctgccgt
    13321 cggtacgtta ttgaaagcct tgccggagtc atgtgcgttg catctggcaa acagttcggt
    13381 ggtgcgctat gcgcagttat actccattcc ttctacgatt gaagtttgtt gcaaccgggg
    13441 aacaaacggc attgaaggct cgctgtctac ggctgtcggt tatgcggcag cttccgataa
    13501 actgaacttt atagctatcg gagatttgag ctttttctat gatatgaatg cattgtggaa
    13561 tgtcaacgtt cgctccaatc tgcgtattct tctactaaat aatggaggag gagagatttt
    13621 ccataccttg ccgggattgg atatgtcggg tacctcacat aaatttattg cggcagtcca
    13681 taaaacgtct accaaaggtt gggcagagga acgtggattt ctctatctgc aagcgcaaaa
    13741 tgacgaagaa ctggctgaag cgatgaaaac tttcacccag ccggaaacta tggaacagcc
    13801 tgtgctcttg gaggtgttta ccaacaaaaa caaggacgcg cgtatgttga agaattatta
    13861 tcatcaatta aaacaaaaat agattatgtc aacacaaaga gagtggacaa ccatcagaga
    13921 atacgacgat attctttttg attattataa tggaattgcc cgtatcacga tcaaccgtga
    13981 gcgttatcgg aatgcgttta ctccgacaac tactgctgaa atgagtgacg cattgcgcat
    14041 ctgccgtgaa gaagcggata ttgatgtgat tgtgattacc ggagccggtg ataaggcatt
    14101 ttgttcgggc ggcgaccaga atgtgaaagg acgtggcgga tatatcggaa aagacggtgt
    14161 gcctcgtctt agcgtattgg atgtgcaaaa gcagattcgc agcatcccga aaccggtgat
    14221 tgctgccgtg aacggttttg ccattggtgg cggacacgtg ctccatgtag tatgtgattt
    14281 atccattgct tcggaaaatg ccattttcgg tcagacaggt cctcgcgtgg gtagctttga
    14341 tgccggattc ggtgcatctt atctggcgcg tgtggtagga cagaagaaag cacgtgaaat
    14401 ttggttcctt tgccgcaagt ataatgcaca agaagcattg gatatgggat tggtgaataa
    14461 ggtagtacct ttggaacagc tggaagatga atacgtgcaa tgggcggaag aaatgatgtt
    14521 gcttagcccg ttggctttgc gcatgattaa agcgggattg aatgccgaac tggacggtca
    14581 ggcaggtatt caggagttgg caggtgacgc aacattactt tattacctga cggatgaagc
    14641 acaggaagga aagaatgcgt ttctggagaa acgtaaaccg aacttcaaac aatatccgaa
    14701 atttccttaa aataataggc taatgaaaga ctggttgtgc agtaattagc agattgaaaa
    14761 gatattcatt atggattgta agatagatat tattccccgg ttgctccatt tcaagcgacc
    14821 cgcgggaact tcccggggaa catatactac acgaaaagtc tggtatcttc actttgcttc
    14881 tcctgatttt ccgggtagag tgggaattgg agaatgtgcg cctttgcctg cgttaagttg
    14941 tgatgatctc cctgattacg aagatatatt aataagaact tgccggcaag tagaggaaga
    15001 acagggaaaa ttggataaag atggtctatg caagtatcct tccatcttat ttggcttgga
    15061 aacggctatc tggcatttct ttgcagggag ttgggctttg tccgatacgg ctttttctcg
    15121 tggagaggta gggattcaaa ttaatggttt gatttggatg ggagattttg atcacatgtt
    15181 atcccaaatc gagaaaaaga tggaagccgg attccgttgt gtcaaactaa agattggtgc
    15241 tatcgatttt gaaaaagaat tggcgttgtt acgtcatatt cgtacccatt tctcttctaa
    15301 agaaatagag ttgcgtgtag atgcaaacgg tgctttctct ccgggtgatg caatggaaaa
    15361 actgaaacgt ctgtcggaat ttgatttaca ttctatcgaa cagccgatcc gtgccggaca
    15421 atgggaggaa atggcccggc tcacttctga atctccgttg ccgatagcat tggatgaaga
    15481 gctgatagga tgcaacatgc tggaagaaaa aaagaaactg ctggcaacca tccgtccgca
    15541 atatatcatc attaaaccat ctctccacgg aggaatatgc ggaggggatg aatggattat
    15601 ggaagcggaa aagcaacata tcggctggtg gatcacttcc gctttggagt ccaacattgg
    15661 tttgaacgct atcgcccatt ggtgtgcaac attcaataat ccgttgccac aaggattggg
    15721 aacgggtatg ctctttactg acaatataga agtgcctctt gaaatcagaa aagattgcct
    15781 gtggttttgt aaatgatagt atttagtggt atttaaagga tattctgatg atatttgatc
    15841 gacaacaaca gcgcttgcta ctggaaggaa aagaatacac ttttgaagat ataagccaac
    15901 tgatagcagg aggagcagaa gctcattctt ctgcttattg ggatttatat cttttcctga
    15961 acgaatggtt taatgattct cctgttatta cagttcatac atcgggctcc acgggtatac
    16021 ctaaagaact gatggtacgc aaggatcaaa tgatgcaaag tgcacgtctg acttgtgaat
    16081 ttctgaattt gaagaaaggt gagtcggcat tattatgtat gaatcttcgt tatatcggtg
    16141 caatgatggt ggtcgtacgt tcattggttg caggcttgaa cctgattgtt cgtcctgctt
    16201 ccggtcatcc gttggcggat ataaaagaat ctttgagatt tgtggcaatg gtcccattgc
    16261 aagtttataa cacgatgcag gttcccgaag aaaaagagcg attaaaacaa acggatattc
    16321 tgattatagg aggcggagcc gttgatgagg ctctggaaac ggagataaac catcttccga
    16381 ctgccgttta ctccacttat ggcatgactg aaactttgtc gcatattgcc cttcgtcgtc
    16441 tgaacggagc atcggcttca gaacattatt atccatttcc ttcagtaaaa ttgtctttat
    16501 ccgcagagaa tacattaatc attgatgccc ctttggtatg tgacgaaaca ttgcaaacca
    16561 atgacattgc acgtatctat cccgatggaa gttttatgat tctagagtag gaaagacaat
    16621 gtgattaaca gtggaggaat taagattcaa gcagaggaga tggagaagtt gctccgcccg
    16681 tttattcctg tgtcctttgt cattacttca gttccggatc agcgcttagg gcaggctgtc
    16741 actttattat tggcagatca gcccgacaca gaagaaatcg gaaataaact acatgaaata
    16801 ctggaacctt attatcgtcc caagcatata ttgacaatag aatccattcc gcaaacagag
    16861 aacggaaaaa taaaccgggc agagtgtcgc atcttagcca aacaaatgtt gatgacattt
    16921 taccctcaca ccctcacacc ttgattcaat ccctttattc atcggtgttt caagtgtgag
    16981 ggtagaggtg aggtcagggt gagggtaact ttttaccctc accctggctc gtcttgttcc
    17041 cagctaattt atactatatt tccctatata tcatacattg atacttaggt attcttttgt
    17101 taagctctaa tgttttacaa gggctcaccc atgtaaacaa atctgtttac aaccgtaaac
    17161 ggatttgttc acaactgata gcttatctgt ccacacaagt aagcccctgc taactattaa
    17221 gcagagtgat ataaacaaca ggactaatac atatatagag tacgactgtt tttcaaaaga
    17281 aaggcatata ccaggaagag aacatgagga tgtagattat gcacgaagaa ataacaagag
    17341 taatagtggc atatactcct ttaattcatt acgtaaaagt tccatcgttt tttgtttata
    17401 tcgattgata gacttcacgc taagattcat ctcttctgca atctctgtat gagttttgcc
    17461 ttcaaagaaa cttttaataa agaccgttcg atagttttcg ggaagtttgt ttaatgtctc
    17521 atacaacatt ctgtatagct catcaagagt atatatacta tccggttctg tttcatagac
    17581 aggagctttc ttctgtatat tttccgcata gctccattca tattcctgat gtttcaggaa
    17641 attcaggcag ctatttttta cgcacatttt gatgtaagct aatgcggtgt tcgattgaag
    17701 atcaaaagaa tcagtatcca gtttatccca taatgaggtg aatacatccg aaacgatgtc
    17761 ttcacgtgtt tctttatcat caacaaacct ttttgcatac aaacaaaatg gggcataata
    17821 ctcctcataa agttgtttga aagcccgttc cttagtctgt ttggaaaaag atattttcat
    17881 tatttagagg ttctgtagtt tttcattttg ctgcaaatat ataataagat aattatcaaa
    17941 gcctaatttt cgattctttt ttttgctttc aacactaatg aatagaaaat aatcagatga
    18001 ggctgtcctt ttgtatatag gttgattgta ttatatataa acgggattaa aatatgaaaa
    18061 acaagttttt tttattggct ataacctttt gtttgccaat acattctcaa ggagtttcca
    18121 agtcttttat tccgatggct gaaatacctg ccggaagttt ttatatggga agtgacggat
    18181 taggcgaaga ttttgatgag gctcctatcc atcaggtaat aatctctcgc ccgtttcgta
    18241 tgggaatcac tgaaataacg aatgcgcaat atgaatcatt ccgtccggaa catcgggcat
    18301 tacgaggaaa aaacggtgtt tcgctggaag atgatgaagc agtcgtcaat gtgagttatt
    18361 ccgatgctgt tgccttttgt gaatggctta gccggaaaga aggcaaaaac tatcgtttgc
    18421 caacagaagc ggaatgggaa tatgcttgtc gggcaggcac atacacacta ttttctacag
    18481 gagacgggtt acctgcagtt tatcatcgga atcaaaaagt ggttcgtgac tttgatccgg
    18541 tatctttaaa agtagcccag actcctccta atacattcgg gctttatgat atgcatggaa
    18601 atgtggaaga atggtgcttg gattggtatg ctccttattc cgcagaaaag cagaaagacc
    18661 cggcaggacc gttgaccgga gagtttcggg tcactcgagg agggagtcat cacaccccgg
    18721 agaaatactt gcgaagtgcc aatcgactgg ctatgctccc ggaagataaa cattcccaaa
    18781 ccggatttag aattgtggaa gcagatactc gtttgaatgt atcgggaaca tctgcccctg
    18841 tcccgttcaa tcagaaatct gtagaaaata catctataaa atggaaaaaa gtatctgcta
    18901 tcacaccgat gtttttgcct ccgataccat ttgtggtacg tccggtatgt gattcgaata
    18961 ccccatttta tctgcataat catcagcctg cagttacgtg gtgtgataat ggagatttgc
    19021 tggcaatatg gttttctgca aatgaagaga atgggagagg gatggtagta ctcggttccc
    19081 gcttgcgtgc cgggcacact gattgggatg tggcttcttt attctttaaa gttccggatc
    19141 ggaatatgac aggaagcgct ttgctcaatg acgggaaagg aaaattgtat catatcaatg
    19201 gagtggaagc atcgggagac tggcagaatc tcgcaatggt actacgtacc agcacagata
    19261 acggtgcttc atggagcact cctaaactga tagctcccga acataccaaa cgtcatcagg
    19321 taatagctgg tacgattcgc acacgtgagg gatggctggt tcaagcctgt gatgcgggtc
    19381 ccggcagtca tgacggggca gctgttcaaa tcagtaaaga tggaggaaaa acatggtgcg
    19441 atccttggga tggcgctcct ttgccggatt tcaaagaagg aggaacggga agtacaatcg
    19501 caggtatcca tgcgggaatt gtacaattag ggaacggaag tttgatggct atggggcgtg
    19561 gtaatagcat acggaataaa gaaggaaagc tccgaatgcc aatgagcata tcagatgata
    19621 tgggaaagac ctggaaatat gtagcaagcg aactccctcc tattgacgga ggtcagcgtc
    19681 ttgttttaat gagactgaat gaaggacctt tgctattggt ttctttcaca gaccatccgc
    19741 aacgtacgcc tttggaagaa cgtggtctgg aatttaagga taaaaatgga aatgtgaaga
    19801 aaggatatgg catgtatgcg gctctttcct acgatgaggg aaaaacatgt acggtaagaa
    19861 aactactgac ggacggtgaa tatcgttttt taaacggtgg agcatggacg ggatatttcg
    19921 aaatggatga aaatcatgct gaaccacgtg gctatcttgc aggaacacaa actcctgata
    19981 atgtggttca tatccttagt agccgattgc attaccgctt caatttggca tggctcgaaa
    20041 aataaaataa aaaaagtttg tttttgctgt ccttttccaa ttacttcagt tgtattataa
    20101 gtgtaattac aattaaaaga taagattttg aaagaaaata tggaaaatat gagtccggaa
    20161 tcattgctcc gtaaagcaca agcattggga gatgatatta aagaaatgga atccattgat
    20221 gtattgggtg cctattatca agcacaaacc aaaataaaaa ctaatagaag aaagaacatg
    20281 tataatcaac tgatgcgtta tgcagcattt ctgactatac ctttatttct ctcttctctg
    20341 gttttgggat atttatattt tagtggaaca gaaaccgacg agaaatatgc agaggtggta
    20401 accgctaccg gttctgtcat acgttatgaa cttccggatc attctgtagt atggttgaat
    20461 gcaggtagta cattgcgtta tcctaccact ttcaagaaag acaaccggtt ggtagaactg
    20521 aagggtgagg catatttcga agtgcaggca gacaaagatc gtcctttcta tgtaaatact
    20581 ccgaatggct tgagcgtata tgtttatggt accaaattta atgtagctgc ttatgaggat
    20641 gataattata tagaaacagt attggaaaag ggtaaggtaa atgtgataac ccccgatcag
    20701 gaaacaatcg tattggctcc tggagaacag ttgctttacg acaaacagag tcaaaagtcg
    20761 aaaaaaaata aagtggatgt ctatggaaag atagcttgga aagatggaaa actaattttc
    20821 agaaatgctt cattagaaga aatcctgaag cgtctggaac gacatttcaa tgtagaaatt
    20881 cagtttaaca ataggtctgg aaaagaatat aagtaccggg ctactttccg gactgaaact
    20941 ctgtcgcaga tattggatta tcttaccagg tctgccgatt taaaatggaa aattgaagaa
    21001 ccgcaacaac aggcagatga tacattatca aagactaaaa ttagagtaga tttatattag
    21061 agtagtaacc cttaaaataa aaataccatg gaataacaca agagaataaa agaaaggaag
    21121 aaagctgcta ccaacagctg tcttcctccg aattttccag attcacggta caaggtctcg
    21181 caaacactag ccggaatcaa accatagttc atttagtaat aaactttagt tagccacaaa
    21241 tgtatgaaaa aaaatcattc atttacagca ttatgtccta aatatgcttt aaatctaaaa
    21301 cttcctttag ttatgaggat tagtctagca ctacttttcg cagtagtatt acaactttct
    21361 gccgaagatg gctatgccca gcgaacgcgg gttgccattt caatgaacaa tgtatctgta
    21421 gaacaggtac tgaataaaat agaggagacg tccgactatg ttttccttta taatgataaa
    21481 acaattcaga agaatcgtat tgtttctgtg agaaacaatt caggtaagat cctggatatt
    21541 cttgatgagg tatttaaagg aaccaacatt acttatacag tggttgataa gcagattatc
    21601 ttgtctacca ataaattgaa tgtaacagag caagatccga ctattcaggt aaaaggtaca
    21661 gtgaaagata caaaaggaga acctttgatc ggagtgaatg tgaaagtaaa agggacaact
    21721 accggtgcta ttacagattt cgacggaaac tttcagattc aagctaaaaa gggagcggta
    21781 ttggagatct cttatattgg atatgcttct caagaggtga aggttacaga taataaatcg
    21841 ctttccattg tgatgacgga agatgcaaaa gtcttgaatg aggttgttgt aacggctttg
    21901 ggcattaaac gcgaaaccaa gtctttgaca tacaatgtgc agcagattgg cggcgacgaa
    21961 gtggcaaagg cgaaagatat gaatgtgatg agcagtcttg ccggtaaggt ggcgggtgtg
    22021 aatatcaatg caagttcatc cggtattgga ggcggtgccc gtgtggtaat gcgtggtacg
    22081 aagtctatat caggtaataa caacgctcta tatgtagtag atggagttcc tttggctaat
    22141 atatcaggtg aacaacccga cgatcagtat acgggtgccg gacaatccgg tgacggattg
    22201 gctaacttca acgctgatga tatagaatca atttcagtac ttagcggatc gtaccgccgc
    22261 tgcactatac ggttcggctg ctgccaatgg tgtggtactt atcacaacga agaaaggagc
    22321 tgtagataaa accagattga cttacagtaa taattcaact ttctattcac cattccgatt
    22381 gccggaattc cagaatacgt atggttcgga aactggagag tggtatagtt gggcatctaa
    22441 attgtcatct cctaccgatt atgaagttaa agattttttt cagacaggtt acaatgtagc
    22501 aaacactgta agtctgacta cagggacaca aaaaaatcaa acctatgtat ccgtaggtgc
    22561 tgtgaatgcc cggggtatca ttcagaataa tgacttggac agatataatt tctctgttcg
    22621 taacacgacc tctatgctga atgataaact gacgatggat ttaagtttta tgtattctaa
    22681 tgtaaaggaa cagaatatgt tgtcgcaagg agagtatgcc aatccattgg ttcccgttta
    22741 tttatttccg cgcggtgatg atttctcgaa atatcagtat tatgaacgat atgatgtaga
    22801 ccgtaacata aaaacacagt tctggtccat tgaaagaaaa tggattatcc atgcagaatc
    22861 cttactggat tacgaaccgg aatatgtata ccaacaagaa agaccgtttt ctggcaagcg
    22921 gttcactaaa atatacgata acagattggt tgaatgtttc cggacgcgtg aaactggata
    22981 aggaaactat caactcggaa aagaaaatgt atgcttccac tttgaatgtg attgctgaaa
    23041 actcggataa aggagcatac gtgcaatcga acaagaatac cagtcagata tatgcggatg
    23101 ccatgttgaa tatcaataaa tatttctatc acgacacatg gaatctgaca gcatctttag
    23161 gtgccagttt attggatttg gattataagg aacttaattt tggcggcgga ttgctgacca
    23221 ttcctaatct gtttacttct aacaatgcga acgtttccgg taaattaacc tataaaaata
    23281 cgaactatca cgaccgtacc aattctttat tcggaacatt ctcattagga tataagggca
    23341 tggtttatgt agatggttcg ttacgtaatg actggatatc tgctttggca ggaacaaacc
    23401 attcttccat attatatcct tctatcggtg cttcagcgat tctgactaat atgtttacaa
    23461 tgaaatctaa cattctttct tatgcaaagg tccgcctttc atatagtgag gtgggtaatg
    23521 caccggaaag attcagggct atcactactt acgcagtgtt gggagggttg aataccactt
    23581 cttatttccc gataaaagac cttaaaccgg agagaactca ttcatgggaa ggaggattta
    23641 atttaggtct gtttgataat aaactgacac tggacgtgac agcttataag acatatacgg
    23701 agaatcagct cttcagtccg gaaatttcta caacaaccgg atattctaaa ttatatgtaa
    23761 atgcaggtaa agtaacgaat aaaggtattg agttagctct tggctttaaa cagaatatag
    23821 acctgtagat tggaaaacaa ctttactatg gtcgctcaac agaaaccgca ttgaccaatt
    23881 actccctgaa tatacaaatg aagagttggg agtgacagta catctggacg aaatggatgt
    23941 ctattcgtta ggcggtgcca aacagcggct aacagtaggg ggctctatgg gagatgtata
    24001 tgtgaataca atgagaactg atgagcatgg acatatctgg atgaattcaa tgacgggtac
    24061 attggaaaca gataagaata attatgtcta tgctggtaat accaatccga aatatactct
    24121 tagctggaga aatgaattta attggaaagg aatcagtctc ggatttatgt tgaatgcccg
    24181 tgtaggtggt atcggagttt ctgccactca agctgtaatg gactattatg gagtgtctaa
    24241 gacatcggca gaagcgcggg ataatggtgg cgtgaaagta aactaccaga tgattgatgc
    24301 ccagacatgg tatcagacta tcggagctaa tggtacaggt tatgtaggtt ctatgtatgt
    24361 atatagtatg acgaatgttc gtttgggaga attgacattg ggatatgata ttccgatcaa
    24421 taaatggtgt aaatggattt ctggattgaa tgtgtccttt gtaggacgta atttatggat
    24481 gctatattgt aaggctccat ttgacccgga atctactgca agtacaggta cttataacca
    24541 gggtatggac tatttcatgc aaccgagttt gagatcgatg ggattttctg caaagatttc
    24601 tttctaattg gataaccttt aaaaaaaata atgatgaaca tacgtaagtt ttttaaagta
    24661 aggaactact acttactcct tggagtaatc atgataaatg taggttgtac
//
