LOCUS       gnlProkkaLMPPAHAM_1    13372 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|LMPPAHAM_1.
ACCESSION   gnlProkkaLMPPAHAM_1
VERSION     gnlProkkaLMPPAHAM_1
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2024-12-01 09:02:45
            Original ID  :: gnl|Prokka|LMPPAHAM_1
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 676243
            Orig. end    :: 689615
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..13372
                     /aStool="rule-based-clusters"
                     /category="other"
                     /contig_edge="False"
                     /core_location="[5000:8372]"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..8372
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /neighbourhood="5000"
                     /product="phosphonate"
                     /protocluster_number="1"
     cand_cluster    1..13372
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(phosphonates and minimum(1,
                     [2-Hacid_dh_C, Aldedh, Aminotran_1_2, Aminotran_5, AurF,
                     CTP_transf_like, DUF4992, Fe-ADH, HMGL-like, Metallophos_2,
                     NTP_transf_3, NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C,
                     TPP_enzyme_N, phosphonates]) and not (phosphonatesHydrolase
                     or phosphonatesMeIsocitrateLyase))"
                     /kind="single"
                     /product="phosphonate"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..13372
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="phosphonate"
                     /region_number="1"
                     /rules="(phosphonates and minimum(1, [2-Hacid_dh_C, Aldedh,
                     Aminotran_1_2, Aminotran_5, AurF, CTP_transf_like, DUF4992,
                     Fe-ADH, HMGL-like, Metallophos_2, NTP_transf_3,
                     NTP_transf_5, PALP, PEP_mutase, TPP_enzyme_C, TPP_enzyme_N,
                     phosphonates]) and not (phosphonatesHydrolase or
                     phosphonatesMeIsocitrateLyase))"
                     /tool="antismash"
     CDS             complement(222..521)
                     /locus_tag="ctg1_805"
                     /transl_table=11
                     /translation="MNQIYDNPNSFGRTYGEHRAFLELDDQAHFEIYKYAKSLGLDFIE
                     TLCAKGCLSLLKLFTPDRLKVASRDLTNLPLLEALAETHIPIILSTRNGWSKRT"
     CDS             complement(505..708)
                     /locus_tag="ctg1_806"
                     /transl_table=11
                     /translation="MKNTYIIGEIGQNHNGSVDLAKLIIELISRPVHEDVFGMDFMPMN
                     AVKMTKKRFIRRIGCFSNESNI"
     CDS             complement(708..1457)
                     /locus_tag="ctg1_807"
                     /transl_table=11
                     /translation="MNYAFVVQARLGSTRLPGKILKPFYGNQSILDLMVHKLSAISNIP
                     VIIATTNSVINEPIEKKALALGVKCFRGEENDVLKRFIDVAEYFDIQGIFRICSDNPFL
                     DVHAARQLVEIAMKSCNDYISFDIDGTPSIKTHFGFWGEFVTLDALKRVIGFTDDLLYR
                     EHVTNYIYSHPELFNIQWISGSPVVSKHHNIRLTIDTLEDFSVAQRIYRDLQEKRVEIS
                     IEVIVDYVRRHAEYIQLMKQQIKKNSK"
     CDS             complement(1817..2725)
                     /locus_tag="ctg1_808"
                     /transl_table=11
                     /translation="MKILKKIFQVIVKIINHCVPVDSRSLYFIPHPNCRTDKYDIINYS
                     SDNVLVLLNYLLKKDSAEYYKIYVEIYDSSRISEYQEYIYGINPNIRCTFLCACVGRFF
                     FNKVSFKDMLYAFFVFVEQVNVLQLLFIMIFHLKNALNRLFVWGYYTPFKDDYHMGDHS
                     YDKFRNTTCNSFDYSIATSCLSARIISIDCGISYDKFKVLGFPRNDLLISKNNCNVIKR
                     EISKFAGYDVTKYIVYTPTFRDYETVTEGNLRSILGYVDCDLLKLSKILLKFNAALILK
                     LHPLQNKTVLKKRFTQRYTCF"
     CDS             complement(2843..3265)
                     /locus_tag="ctg1_809"
                     /transl_table=11
                     /translation="MVGLLVLANPIISLLLTDKWSGVVILLQILCLDWMFDHLSQINLN
                     LLWVKGRSDLSLRLEIIKKTIAIFILFVSIPFGLEVMCWGRVIYSLIATYLNTYYTNSL
                     IDLTLKLQVKDVFPSLILSFIMGGSFLYVFLSLKLI"
     CDS             complement(3333..3887)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_810"
                     /sec_met_domain="Polysacc_synt (E-value: 2.1e-12, bitscore:
                     45.8, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVYCFFSASLIADFYNMPTLVLVIRFIALSLIINALSAIHRTKLI
                     ISVNFKTQSKISLGAAFISGVIGIWMAYVGCGVWALVWQTLLNSIILTILFYCLVHWKP
                     LHTFSKSSFERLFNFGSKLLISSLINTVYRNLYTIVIGKKFSVVELGYYTRAEQFAIFP
                     SNNLNALVSRSSVSYFKFHSR"
     CDS             complement(3841..4128)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Polysacc_synt"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg1_811"
                     /sec_met_domain="Polysacc_synt (E-value: 2.5e-11, bitscore:
                     42.3, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MWSAIERFSLQGVQFIIQIILARLLLPSDYGMIGMLAIFLQVAQV
                     FIDSGFTNALIQKKDRTEEDFATVFYFNILVAVLFYGILFFFGFFDCRLL"
     CDS             complement(4368..4511)
                     /locus_tag="ctg1_812"
                     /transl_table=11
                     /translation="MIAEILLKIRHFYFSLRGIHFHPESVISGVPIRSFRLVGKYGNIN
                     LR"
     CDS             complement(4508..4909)
                     /locus_tag="ctg1_813"
                     /transl_table=11
                     /translation="MHFTPPVQTIYATRQALNEYFEVGEEAKFARHKRVFEAIHSGINE
                     IGLKSVIKREWQSGLVVSVQYPEDPNWDFEKIHDYCYERGFTIYPGKISTEDTFRICAL
                     GEIEVDDIENFFKVLKAALNHYNVTLPMS"
     CDS             complement(5001..5630)
                     /NRPS_PKS="Domain: Aminotran_5 (29-207). E-value: 8.8e-27.
                     Score: 85.8. Matches aSDomain:
                     nrpspksdomains_ctg1_814_Aminotran_5.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: Aminotran_5"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1139:aminotransferase class V (Score: 61.7; E-value:
                     9.6e-19)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_814"
                     /sec_met_domain="Aminotran_5 (E-value: 2e-22, bitscore:
                     78.3, seeds: 34, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKIERKILLNPGPATTTDSVKMAQVVPDICPREKEFAGMMKQLRD
                     DLVRVAHGNLEKHTAVLFCGSGTINIDICLNSLLPEDKRVLIVNNGAYSTRAVEVCQYY
                     GLPHINLEFSVYERPDLSVVENVLQENPDIAMVYTTHHETGTGILNPIREMGAIAHKYQ
                     AKFVVDTTSSLGMIPFDIEKDNVDFCMASAQKGLQAMTGLSFYYRQ"
     aSDomain        complement(5010..5543)
                     /aSDomain="Aminotran_5"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg1_814_Aminotran_5.1"
                     /evalue="8.80E-27"
                     /label="ctg1_814_Aminotran_5.1"
                     /locus_tag="ctg1_814"
                     /protein_end="207"
                     /protein_start="29"
                     /score="85.8"
                     /tool="antismash"
                     /translation="CPREKEFAGMMKQLRDDLVRVAHGNLEKHTAVLFCGSGTINIDIC
                     LNSLLPEDKRVLIVNNGAYSTRAVEVCQYYGLPHINLEFSVYERPDLSVVENVLQENPD
                     IAMVYTTHHETGTGILNPIREMGAIAHKYQAKFVVDTTSSLGMIPFDIEKDNVDFCMAS
                     AQKGLQAMTGLSFYY"
     CDS             complement(5578..6093)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_815"
                     /sec_met_domain="TPP_enzyme_C (E-value: 8e-17, bitscore:
                     60.1, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNMIFLTVGSMGHSSSISLGIAIAKQDRPVYCLDGDGAFIMHLGA
                     ISNIGDLSPKNYYHILFNNGAHESVGGQPTLGFSLDIPAIVRGSGYKHTYTVCTKVEIE
                     EAMKQLPKLCGPVLLEIKVKIDSRENLGRPTTTPIENKEHFMDFFKINIFDENRKKNII
                     KSWACHYY"
     CDS             complement(6053..6586)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: TPP_enzyme_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_816"
                     /sec_met_domain="TPP_enzyme_N (E-value: 1.9e-06, bitscore:
                     26.3, seeds: 75, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MASGKVPVVYMQNSGLGNTVNPLLSLADEQVYSFPMLLMIGWRGE
                     PGTKDEPQHKKQGEVTLDLLKAMRIPYIILDSNENDAFIQLHDIIQSAKTKNIPHAIII
                     RKDVFGKYKLQKEFGCNYPLSREDALQIVVDYLPENSVVVSTTGKLSRELFEYREMKEQ
                     GHEHDFSHGRLYGT"
     CDS             complement(6573..6767)
                     /locus_tag="ctg1_817"
                     /transl_table=11
                     /translation="MLSVEKVYETFLSHDVDFFTGVPDSLLKNICAYITDHTSREKHII
                     AANEGAAIGIASRLLYGIR"
     CDS             complement(6784..7758)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: phosphonates"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: PEP_mutase"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1231:carboxyvinyl-carboxyphosphonate (Score: 210.3;
                     E-value: 5.7e-64)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_818"
                     /sec_met_domain="phosphonates (E-value: 4.2e-119, bitscore:
                     395.6, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PEP_mutase (E-value: 5.2e-61, bitscore:
                     204.9, seeds: 69, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEQGGKVIEIPYTLGINSSSLDKDIKAIGTTPDVRLKSLRRLIN
                     AKPVVRILEAHDGLCGLIIENQEILKGDKREVFDGMWSSSLTDSTSKGKPDIEAVDLTT
                     RLQDLNNILECTTKPIIFDGDTGGKIEHFVFTVRTLERHGISAIIIEDKVGLKKNSLFG
                     TDVIQTQDTIEGFCNKIKAGKASQITDDFMIIARIESLIAGKPVSDALERAFAYVQAGA
                     DGIMIHSKNKSGEDIKEFCLAFRKQYAHVPIVVVPTTYDHIYESELCDWGVNIIIYANH
                     MLRAAYPAMMNVAKIILENERALEVRELCMPIKEILELIPGTK"
     CDS             complement(7758..8372)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     phosphonate: NTP_transf_3"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1064:glucose-1-phosphate
                     adenylyl/thymidylyltransferase (Score: 55.1; E-value:
                     1e-16)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg1_819"
                     /sec_met_domain="NTP_transf_3 (E-value: 5.5e-14, bitscore:
                     51.5, seeds: 297, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIRTAMIMAAGMGTRFGQYTELIPKGFVKVGGIPMIVRSIDTLLS
                     CDIERIVIGTGYKQEVYEELKTDYPMLETCFSPRYAETNSMYTLYNTREILGNDDFLLL
                     ESDLIFEKQAIMSLLECPAADAMLITPVTKFQDQYYVEHDDNFRLSSCSVNKNKLNAKG
                     ELVGIHKLSGSFYKIMCADYASMVTTGKPGLYVKNVCAYLK"
     CDS             complement(8436..8834)
                     /locus_tag="ctg1_820"
                     /transl_table=11
                     /translation="MERLFKERQQEYYAAQRKYADYVDAHDNVVLQSVRAEQERLQNDM
                     SLAYQIYSQVANQLQVSRAKVQEEKPVFAVVEPAVVPLKPSGMGLKIYILLFVFLSVSG
                     TLVWVFFGKSLLASLRKELKNKEIEQDK"
     CDS             complement(8818..9186)
                     /locus_tag="ctg1_821"
                     /transl_table=11
                     /translation="MTLGSYLDEESSPWWDYLIGFPGIVIGGVKSLFGEDTVPASGGRQ
                     GTIELTKEVNEKINFLKKKISASIDKKTAITSITVTLQNPQITAVIADSVVHKLQEYII
                     GYRTSKVKRRLCVFGTVV"
     CDS             complement(9200..9586)
                     /locus_tag="ctg1_822"
                     /transl_table=11
                     /translation="MIEKQSYQEPFSEVDKRKDDEMEIDLMAIFYKIITVRGVLCKAAG
                     VGVIIAIVVALSIPKQYTVKVTLSPEMGNAKGSNGLAGLAASFLGDGALIGESTDALNA
                     SLSADIVSSTPFLLELFRNGSLRF"
     CDS             complement(9597..10754)
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 41.7;
                     E-value: 1e-12)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_823"
                     /transl_table=11
                     /translation="MKLRGLTGDAFLNRAVLYRQREDLTSEVVQIDIRSIMDGTSPNLA
                     LMKNDILYIPSIHDLEDRGNVTVHGEVAQPDSYPYADNMTLEDLIIQAGGLKEAASTVR
                     IDVSRRIKNPRSTADNDTIGQMYTFSLKDGFVIDGQPGFILQPYDEVYVRRSPGYQAQQ
                     NVAIEGEILFGGNYAMTSREERLSDLVNKAGGPTNYAYLRGAKLTRVANASEKKRMGDV
                     IRLMSRQLGEAMIDSLGIRVEDTFTVGIDLEKALSNPKSNADLVLREGDVISIPNNNNT
                     VTINGAVMVPNTVSYMQGKDVDYYLNQAGGYSDNAKKSKKFIVYMNGQVTKVKGSGKKQ
                     IEPGCEIIVPGKAKKKGNIANILGYATSFSSLGMMIASIANLIKK"
     CDS             complement(10729..11967)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Poly_export"
                     /gene_functions="transport (smcogs)
                     SMCOG1186:polysaccharide export protein (Score: 127.3;
                     E-value: 9.6e-39)"
                     /gene_kind="transport"
                     /locus_tag="ctg1_824"
                     /sec_met_domain="Poly_export (E-value: 1.7e-16, bitscore:
                     58.7, seeds: 183, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLGSGSLMAQSMSDSQVLEYVKDGIRQGKEQKQLASELARKGVTK
                     EQAMRVKQLYEQQNNVNTSKSTGTDINESRLREETKENTSDMLEDHPTTQDLARGDQVF
                     GRNIFNTRNLTFEPSVNLATPTNYRLGPGDEVIIDIWGASQNTIRQQISPEGTINIQKI
                     GPVNLSGMTVSAANDYLKNALNKIYNGLNNTTDPTSDIRLTLGNIRTIQINVMGEVVQP
                     GTYALSSFSTVFHALYRAGGVSDIGSLRNVQLVRNGKNIATIDVYEFIMKGNTQDDIRL
                     QEGDVVIVPAYDVLVKISGKVKRPMRFEMKKEENLATLIKYAGGFEADAYTRSLRVVRQ
                     NGEEYEVNTVKDIDYSIYKMRNGDVVTAEAILNRFTNKLEIRGAVYRPGIYQLSGKLNT
                     IRELVNEAQGADR"
     CDS             complement(12027..12395)
                     /locus_tag="ctg1_825"
                     /transl_table=11
                     /translation="MDAIILQENIEGLLSLVRMLLPGGGSAGCVYLDDLSALQRSIHEK
                     INDLYSQRGETPEQDATLCLAILQGYNVSMYANPEDEERKQAVLTRSLSLLDVLPPSLL
                     KQQLSAVCHGMQELCEIN"
     CDS             complement(12406..12591)
                     /locus_tag="ctg1_826"
                     /transl_table=11
                     /translation="MNSSPLARGEKVRVIKGPLTGLVGELVNVDGKSKIAVRLNMLGCA
                     CVDMPVGYVEPIMAAV"
     CDS             complement(12594..12986)
                     /locus_tag="ctg1_827"
                     /transl_table=11
                     /translation="MILRKKKSLNAGPINGTGEGVAHSKRWYVALVRMHHEKKVSEHLD
                     KMGIENFVPVQQEFHQWSDRRKLVTSVLLPMMVFVHVDPKERMEVLSFSTVSRYMVMRG
                     ESSPAVIPDEQMARFRFMLDYSGKNR"
ORIGIN
        1 ttacatgctt ttctataatt tccgctccca tcgctacagc agctgtagca gcagaaatac
       61 ctattgtatg atcagaaaaa cctatctcaa acttattgta atgcttcttc aaatatgtta
      121 ttgtacgtag attcaaatta tttggatgag ttggatactg agatacacaa tgtagaatag
      181 ctatattact atgatatctc gttatcacat ctaatgcatt gtcaagttct ctttgaccag
      241 ccattccttg tcgataatat aataggaata tgagtttctg ctaatgcttc aagcaatggt
      301 aagttagtca aatcacgact agcaactttt agcctatccg gtgtgaacag tttaagcaaa
      361 gacagacatc ctttggcaca taacgtctcg ataaaatcta atcctaatga cttagcatat
      421 ttataaatct caaaatgcgc ttgatcatca agctcaagaa aagcacgatg ttcaccataa
      481 gtacgcccaa aagaattagg attgtcatat atttgattca tttgagaaac agccaattct
      541 tctgataaat ctctttttag tcattttaac agcattcatt ggcatgaaat ccataccaaa
      601 aacatcctca tgtacaggtc gtgagattaa ttcaataatc aacttagcca agtcaacaga
      661 accattatga ttctgcccta tttcaccaat aatataagta ttcttcatta tttagaattt
      721 ttttttattt gttgtttcat cagttgaatg tattctgcat gtcttcgaac atagtctaca
      781 atcacttcta tcgatatttc cactcttttt tcttgtaaat ccctatatat tctctgtgct
      841 acagaaaaat cttctaacgt atcaatcgtg agtcgaatat tatgatgttt tgacacgact
      901 ggagatcctg aaatccattg aatattaaaa agttcaggat gactatatat ataattagta
      961 acatgttcac gatacaataa atcatcagta aatcctataa ctcgcttcag cgcatcaagc
     1021 gttacaaatt ctccccaaaa accgaaatga gttttaattg atggagtacc atcaatatca
     1081 aaacttatat aatcgttaca agatttcatt gctatttcga ccaattgcct tgccgcatgt
     1141 acatctaaaa atggattatc agaacatatt cggaatatac cctgtatatc aaaatattca
     1201 gcaacatcaa tgaatcgttt taaaacatca ttctcctcac ctctgaagca ctttacccct
     1261 aatgcaagtg ccttcttttc aataggttca ttgataacag aatttgttgt agcaataatt
     1321 actggaatat tcgatatagc agaaagctta tgaaccatta agtcaagaat cgattgatta
     1381 ccatagaaag gtttcaatat ttttccaggc aaacgtgtag aacctaaacg tgcctgcacc
     1441 acaaatgcat aattcatttt atttattata tttcatttaa aaatatgtca catattctct
     1501 ttgttgaatt atcatcttga aattgattca tcaataaaga aatatgacgt cgatgttcag
     1561 catgaatatc tttcccagcc agaagtccca tcacagcatc tatcaattca ttataattgt
     1621 aaacaatatc acctgcacaa aaaattctat tggctcaaat gagaaacctc ttactctacg
     1681 atattcttca atatcgtaga aattaaatat gactggctta tttaccaata aaaaatcaaa
     1741 ataggtagaa gtataatcag taatcattcc atctgaaaat gacaaaagat catacaatcc
     1801 atatttatat gtttgttcaa aaacaagtat acctttgggt aaatcttttt tttaagactg
     1861 ttttattctg caaaggatgt aatttaagaa ttaaagccgc attaaacttc aatagtattt
     1921 tcgataactt caacaaatca caatcaacat atccgagtat tgaacgcaaa ttaccttcag
     1981 taacagtctc ataatcacga aaagttggag tataaactat atatttagtt acatcatatc
     2041 ccgcaaattt cgaaatttct cttttaataa cattgcaatt atttttcgat atcaacaaat
     2101 catttctggg aaatcctaag actttgaatt tatcatatga gattccacaa tctattgaaa
     2161 ttattctagc acttaaacaa gaagtagcaa tagagtaatc aaatgagtta catgttgtat
     2221 tacgaaattt atcataagaa tgatctccca tatgataatc atctttgaat ggagtataat
     2281 acccccaaac aaataatctg ttgagagcgt tttttaaatg aaaaatcata ataaaaagta
     2341 gctgtaaaac atttacttgc tctacaaaaa caaaaaaggc atacaacata tccttaaaag
     2401 atactttatt aaagaaaaaa cgtccaacac atgcacataa aaaagtacac ctaatattag
     2461 gatttatgcc ataaatatat tcttgatatt ctgaaatacg agaagaatca taaatttcaa
     2521 catatatttt ataatattca gcactatctt tttttagcaa ataatttaac agaacgagaa
     2581 cattatctga cgaataattt ataatatcat atttatctgt tctacaatta ggatgaggaa
     2641 taaaatacaa tgatctacta tcaactggca cacaatggtt aattatcttt actattactt
     2701 gaaaaatctt ttttaatatt ttcatctatg tttttagttt taatgatcaa tgttaaaata
     2761 caaaaaaaaa gaatctagct taaaagaaaa gaaagtaaaa tatagaagga catcccagta
     2821 atacatccaa tcacaatttt tactatatca gtttcaaaga aagaaataca tataaaaacg
     2881 atccccccat tatgaaagag agtattaaac ttggaaatac atctttaact tgcaacttta
     2941 aggtcaaatc aataagagaa ttagtataat atgtattcaa atatgtcgct atcagagagt
     3001 aaataactct accccaacac atcacctcaa gcccaaatgg aattgacaca aaaagaatga
     3061 atatagcaat cgtctttttt attatttcaa gacgtaacga cagatcagat cttcctttaa
     3121 cccataataa attcaaatta atttggctca aatgatcaaa catccaatcc aaacataata
     3181 tctgtaaaag aataacaacc ccagaccatt tatctgttaa caatagacta ataataggat
     3241 tagccaaaac aagtaaacct accattaaag gaaaaattat atatgaggat aatctgatat
     3301 aatttcgata tgcgtttgtt aaacatttat catcatcttg aatggaactt aaaataggat
     3361 acgctacttc tagaaactaa agcatttaaa ttattggaag gaaaaatagc aaattgttct
     3421 gctcttgtat agtaaccaag ctctacaaca gaaaactttt ttcctattac aatggtatac
     3481 agattacgat atactgtatt gataagactt gagatcaata atttagatcc gaaattgaat
     3541 aatctttcaa aagaactttt ggagaaagta tgtaaaggtt tccaatgaac taaacagtaa
     3601 aacaaaattg tcaaaattat actatttaag agagtttgcc aaactaaagc ccaaaccccg
     3661 caaccgacat aagccatcca tattccaatc acgcctgata taaaagctgc acctaatgaa
     3721 attttagatt gagttttaaa gtttacagaa ataattaatt tcgttctgtg aatagccgat
     3781 aaagcattta ttatcaacga caatgctata aaacgaatta caagaactaa agtcggcata
     3841 ttataaaagt ctgcaatcaa agaagccgaa aaaaaacaat ataccataga ataatactgc
     3901 gacaagaata ttaaaataaa agacagtggc aaaatcctct tcagttctat cttttttctg
     3961 gattaaagca tttgtaaaac cgctatctat aaatacttga gcgacttgaa gaaaaatagc
     4021 taacatcccg atcataccat aatccgatgg tagtaacaaa cgagctaata ttatttgaat
     4081 tataaactgt actccttgta aagagaaacg ttctatagcg ctccacatta ttcctgatac
     4141 agttttctgc tttagatttt ccattactta aatacagtat aaaaacaact acatttaccg
     4201 atatcaatta tatttttcca atattctcac taattggtta ttatcttctt cgccccttac
     4261 cgcaattcta atatggtctc tcccactaaa agcaaattac cctacacaaa cattatctcc
     4321 tataactacc gatgcctttt ttataagaat aaagaactcc taatgcatca cctcaaatta
     4381 atattgccat atttgcctac taagcgaaag ctacgaatag gcactccaga aataacactt
     4441 tccggatgga agtgtatacc acgaagggaa aaataaaaat gacgaatctt caataatatt
     4501 tctgcaatca tgacatcggt aatgtgacgt tataatgatt taatgcagct tttagtactt
     4561 taaagaagtt ctcaatatca tctacttcta tctctcctaa agcacagatt ctaaaagtat
     4621 cctcagttga tatcttacct ggataaatcg taaatccacg ctcataacaa taatcatgta
     4681 ttttctcaaa atcccagttg ggatcttctg ggtattgaac tgagacaacc agtcctgact
     4741 gccattcacg ctttattaca cttttaagac caatttcatt tatacctgaa tgaatagcct
     4801 caaaaactct tttgtgacgg gcaaacttag cttcttcacc cacttcaaaa tattcattta
     4861 atgcctgacg agtggcgtaa atagtttgta ccggtggagt aaaatgcatt tcacctgttc
     4921 tctcaaaatt ctcatactgc aaataaagat tacaatagta agaacgcttg ggatattttt
     4981 ttgaaaactt aatctgttcc tcattgccta taataaaaag aaagacctgt catcgcttga
     5041 agtccttttt gagcagatgc catacaaaaa tccacattat ctttctctat atcaaaagga
     5101 atcatgccca aagaagaagt agtatcgacg acaaatttag cctgatattt atgagctata
     5161 gcgcccatct cgcgaatagg gttcagaatt cctgtacccg tctcgtgatg agtagtataa
     5221 accatagcta tatcaggatt ttcttgcaac acattttcca ccaccgataa atcaggacgt
     5281 tcgtaaacgg aaaattccaa attaatatga ggcaaaccat aatattgaca cacttctaca
     5341 gcacgggtac tatatgcccc attattcact ataagcaccc ttttgtcttc aggaagaaga
     5401 gaatttagac atatatcaat attgatggtt cctgagccac aaaataatac agcggtatgt
     5461 ttttccaaat tcccatgagc aactctgacc aaatcgtccc gaagttgttt catcatacct
     5521 gcgaattctt tctcgcgagg acaaatatcc ggaacaactt gtgccatttt tacactgtca
     5581 gtagtagtgg caggcccagg atttaataat atttttcttt ctattttcat cgaatatatt
     5641 tattttaaaa aaatccataa aatgctcctt attctctata ggagtagtcg tgggacgtcc
     5701 caaattctcc cgagaatcta ttttaacctt tatttccaac aaaacaggac cacataactt
     5761 tggaagctgc ttcattgctt cttcaatttc aacttttgta caaacagtat aagtatgctt
     5821 atatccgctc ccccggacaa tagccggaat atctaaacta aatcctaaag taggctgtcc
     5881 tcctacagac tcgtgagcac cattgttaaa caaaatatga taatagtttt taggagataa
     5941 atcgccaatg ttactaattg cccctaaatg cataataaat gctccatcac catccaagca
     6001 ataaacaggt ctatcttgct ttgctatagc aatacccaaa gagattgatg aactatgtcc
     6061 catagagcct accgtgagaa aaatcatgtt catgaccttg ctctttcatt tctcgatatt
     6121 caaataactc acgagaaagc ttgccagtag tagaaacgac cactgaattt tcaggcagat
     6181 aatccacaac tatttgcaaa gcatcctcac gagataaagg ataattacat ccgaactctt
     6241 tttgaagttt atatttgcca aaaacatctt tccgaataat tattgcatga ggaatattct
     6301 tagtttttgc tgattgtatg atatcatgga gctgaataaa tgcatcattc tcatttgaat
     6361 caagaattat ataaggaatc cgcattgctt tcaacaaatc taaagttacc tcaccctgtt
     6421 ttttatgctg aggttcatct tttgttcccg gttcaccacg ccagccaatc atcaaaagca
     6481 ttggaaaact gtatacttgt tcatctgcaa gagacagcag aggattaaca gtattaccca
     6541 agccggaatt ttgcatataa accacaggaa ccttacctga tgccatataa taacctggaa
     6601 gcaattccta tagccgcacc ttcattagca gctatgatat gtttctcacg tgaagtatgg
     6661 tctgtgatat aggcacaaat attttttagt aatgagtctg gaactcctgt aaaaaaatca
     6721 acgtcatgac tcagaaacgt ttcataaact ttttctacgc ttaacataat gatattcctc
     6781 tttttattta gtacctggaa tcagttccaa tatttctttt atgggcatac acagttcgcg
     6841 cacctctaaa gcacgttcat tctctaatat tatctttgcg acattcatca tagcaggata
     6901 agcggcacga agcatatgat tagcataaat aattatattc acaccccaat cacacaattc
     6961 agactcataa atatgatcat atgtagtagg cacaaccacg ataggtacat gagcatactg
     7021 ttttcgaaac gccaaacaaa attcttttat atcttcaccc gacttatttt tgctatgtat
     7081 cataataccg tccgctcccg cttggacata tgcaaaagct ctctctaaag catcacttac
     7141 cggctttccc gctataaggc tctcaatacg agcgataatc ataaaatcat cagtaatctg
     7201 agatgccttt cctgctttga tcttattaca gaaaccttcg attgtatctt gagtttgaat
     7261 aacatctgta ccaaacaatg aattcttttt taatccaact ttatcttcaa ttattatagc
     7321 tgaaattcca tgacgttcta aagtgcgtac tgtaaatacg aaatgttcaa ttttaccacc
     7381 tgtatctcca tcaaaaataa taggtttagt agtacactcc agaatattat tcaaatcttg
     7441 caatcgggta gttaaatcaa ccgcctcaat atcaggttta cctttactgg ttgaatccgt
     7501 aaggctacta gaccacattc cgtcaaatac ttccctctta tcccctttta atatttcctg
     7561 attttcaatt atcaagccac atagtccatc atgagcttcc aaaatacgaa ctacgggttt
     7621 ggcatttatc aaacgacgaa gtgattttaa acgtacatca ggggttgtac ctatagcctt
     7681 aatatcttta tccaaagaag atgaattaat tcccaaagta tatggaattt cgataacctt
     7741 tcctccctgt tcattcatca cttcaaatac gcgcacacgt tcttcacgta aaggcccggt
     7801 tttccagtcg tcaccatact cgcataatca gcacacatta ttttgtaaaa ggaaccggat
     7861 agtttatgga tgccgaccaa ttcgccttta gcgtttagtt tattcttatt gacagaacat
     7921 gaagaaaggc gaaaattatc atcatgttcc acataatact gatcttgaaa ctttgtcact
     7981 ggagttatta gcattgcatc tgccgcagga cactccaata agctcattat tgcttgtttc
     8041 tcaaaaatca aatctgactc taacaataaa aaatcatcat tgcccagaat ctcccgcgta
     8101 ttatataaag tatacatact atttgtttca gcataacgag gactaaaaca ggtttcaagc
     8161 ataggatagt ctgtcttcaa ttcttcataa acttcttgtt tatatcctgt accgattaca
     8221 attcgctcaa tgtcacatga taacaaagta tcaatagaac gaactatcat tggaatacct
     8281 cccactttga cgaacccttt aggtatcaat tctgtatatt ggccaaaacg ggttcccatg
     8341 cccgcagcca ttatcatagc tgtacgtatc attcgtttaa taatatagta agtgaattta
     8401 attgatgtaa gaatgttgta aacgacgttt tagcatcatt tatcctgttc tatctcctta
     8461 tttttcagtt cttttctcaa gctagccagc agacttttgc caaaaaacac ccacacgaga
     8521 gtaccagata cggacaggaa cacaaataat aaaatataaa ttttgagtcc catacctgaa
     8581 ggtttcaaag gtacaacggc aggctcaact actgcaaaga ctggcttttc ctcctgtact
     8641 ttggctctgg atacctgcaa ctgattagca acctgactat atatctgata agccaaactc
     8701 atgtcgttct gtaaacgctc ctgctcagca cgtacacttt gaagaaccac attatcatgg
     8761 gcgtctacat aatccgcata ttttctttga gcagcataat attcctgctg acgttcttta
     8821 aacaaccgtt ccaaatacgc acagtcttct ttttactttt gaagttcgat acccaataat
     8881 atattcctgt aatttatgaa cgacagaatc tgctataacc gcagtgatct gcggattttg
     8941 taaggtgacc gtaatgctcg ttatggcggt tttcttatca atggatgcac taatcttctt
     9001 tttaagaaaa ttaatcttct catttacttc tttcgtcaat tcgatagttc cttgccgccc
     9061 tccactggca ggaaccgtat cttctccgaa taatgattta actcctccta ttactatgcc
     9121 cggaaaacct ataagataat cccaccaagg agatgactct tcatcgagat aagaccccaa
     9181 agtcatttta tcatcctttt tagaaacgga gacttccatt tctaaaaagt tccaataaaa
     9241 aaggagttga agaaacaata tctgctgaaa gagaagcgtt caaggcatct gtgctttccc
     9301 ctattagagc cccatctccc aaaaacgagg cagcaagtcc ggctaaacca ttacttccct
     9361 tcgcattacc catttcagga gaaagggtaa cctttactgt atattgcttg ggaatgctca
     9421 atgccaccac tatagcaatt attactccca ctccagcagc tttgcatagt actccacgaa
     9481 cagtaataat cttataaaaa atagccatca agtctatttc catttcatca tctttccttt
     9541 tatccacttc agaaaacggt tcttgataag attgcttttc aatcataata ggtcatttat
     9601 ttctttatca aattagcaat agaagcaatc atcattccca aagaactgaa ggaagtagca
     9661 taacctaaaa tattagctat gttccctttc ttcttagcct taccaggcac aataatctca
     9721 cagcccggtt caatctgttt cttgccgcta cccttaacct tcgttacctg accattcata
     9781 tatactatga acttcttact cttcttcgca ttatcagaat aaccaccggc ttgattcaaa
     9841 tagtagtcta catccttgcc ctgcatataa gaaaccgtat tcggaaccat gacagcacca
     9901 ttgatagtta cggtattatt attattaggt atggagatca catctccttc acgtaagaca
     9961 agatcggcat tacttttagg attgctcaag gctttttcca aatcaattcc aaccgtaaag
    10021 gtatcttcga cacgaatacc caaagagtca atcatggcct cgcccaattg cctgctcata
    10081 aggcgaatta catcacccat acgtttcttc tcactagcgt tagccacacg ggtcagtttt
    10141 gcaccacgca gataggcata attggtcgga ccaccggctt tattcaccaa atcggaaaga
    10201 cgttcctcac ggctggtcat ggcgtaattt cctccgaaaa ggatttcacc ttcaatggct
    10261 acattctgtt gtgcctgata gccaggacta cgacggacat aaacttcatc ataaggctga
    10321 aggataaaac cgggctgacc gtcaatgaca aaaccatcct ttaaagagaa ggtatacatc
    10381 tgaccgatcg tatcattatc cgcagtacta cgaggattct tgattcgtct tgatacatca
    10441 atgcgaacag tagaggcggc ttctttcaag ccaccggcct ggatgatcag atcctcaagt
    10501 gtcatgttat cagcataagg ataggaatcc ggttgggcaa cctcaccgtg aactgtgaca
    10561 ttgccacgat cttccaggtc gtggatactt gggatgtaga ggatgtcatt cttcattagg
    10621 gcaaggttcg gcgaagtgcc gtccatgata gacctgatgt ctatttgaac aacttcactg
    10681 gtcaggtcct cacgctggcg atagaggaca gcacgattca gaaaagcgtc accggtcagc
    10741 cccctgagct tcattgacca gttcgcggat cgtattcaat ttaccgctga gctggtagat
    10801 gccggggcgg taaactgcac cacggatttc cagtttgttt gtgaagcggt taaggatggc
    10861 ttcggctgtt acaacatcgc cgttacgcat tttataaatg ctgtaatcta tatctttgac
    10921 tgtgttgact tcgtattcct caccattctg acggacgaca cgtaatgaac gggtgtaggc
    10981 atcggcttca aagccgccgg catatttgat taaagtggca aggttctctt ctttcttcat
    11041 ttcaaaacgc ataggacgtt ttaccttgcc gctgatcttt accaatacat cataagcggg
    11101 aacaatcacg acgtcacctt cctgaaggcg gatgtcatcc tgtgtgttgc ctttcatgat
    11161 aaattcgtag acgtcgatgg tggcgatatt ctttccgttg cgtactaatt gaacgtttcg
    11221 gaggctgccg atatcactca caccgcctgc acggtaaagc gcatggaaga cggtagagaa
    11281 ggaagaaagg gcgtaggtac ccggctgcac gacttctccc atcacattga tctggatagt
    11341 acggatatta cctaaagtca gacggatgtc ggaagttgga tcggtcgtgt tgttcagacc
    11401 gttatatatt ttattcaggg cgttcttcag atagtcattg gcggcagaga ctgtcatacc
    11461 gctaaggttg acagggccga tcttctgaat gttgatagta ccttcaggag agatttgctg
    11521 gcggatcgtg ttctggctcg caccccagat atcaatgatg acttcatcac cgggaccaag
    11581 acggtaattg gtaggagtgg ccagattaac actgggttca aatgtcaggt tacgggtatt
    11641 gaagatgttg cgcccgaaga cctgatcgcc acgggcaagg tcctgagtag tcggatgatc
    11701 ctccagcata tcagaagtat tctccttagt ctcttcacga aggcgggatt cgttgatgtc
    11761 cgtgcccgtt gatttcgagg tgtttacatt gttctgctgc tcgtatagct gcttcacacg
    11821 cattgcctgt tctttggtta cacccttacg ggctagttcg gaagcaagct gcttctgttc
    11881 cttgccttgg cggatgccgt cttttacata ttccagtacc tgtgagtcac tcatggactg
    11941 agccataagc gagccacttc ccagcatcaa acaaaatagt agaatgctaa aaagtcgttg
    12001 tattttcatt gacaaataaa aaagtttcag ttgatttcac acagttcctg catcccatga
    12061 cagacggcag ataactgttg cttaagaaga gaagggggaa gaacatcgag aagagacaga
    12121 gaacgggtca aaacagcctg ttttctttct tcgtcttccg gattggcgta catcgacaca
    12181 ttatatccct gaaggatggc caaacacagg gtagcatcct gctccggtgt ctccccccgt
    12241 tgagaatata aatcgttaat cttttcgtgg atggatcgtt gtaatgctga aagatcatcc
    12301 aaatacacgc agcctgcact ccccccacca ggaagcagca tacgtaccaa acttaataaa
    12361 ccctctatat tttcttgtaa aataatagca tccatatccc ttgccttaaa cagccgccat
    12421 aatcggctct acataaccga caggcatatc aacacaggcg catcccagca tattcaagcg
    12481 aacagcaatc ttacttttac catccacatt gaccagttcg ccaacaagac ccgtcaacgg
    12541 acctttgatc acgcgaacct tttcgccacg agccaaagga gaactgttca tgcttatcga
    12601 ttcttccccg aataatcaag catgaaacgg aaacgagcca tctgctcgtc aggaattaca
    12661 gcaggactac tctcgccgcg catcaccatg taacggctga cagtagaaaa actcaggact
    12721 tccatgcgtt ccttagggtc aacgtgtacg aagaccatca taggaagcaa gacggaggtg
    12781 accagcttgc gacggtcgct ccattggtgg aattcctgtt gaacgggaac gaaattctcg
    12841 atacccatct tgtccagatg ctcggaaacc ttcttttcat ggtgcatccg aaccaaagca
    12901 acataccagc gttttgagtg tgctacgcct tcccctgtcc cattaatagg cccagcattt
    12961 agtgatttct tttttcttaa aatcatattt ttttacccca tgtttatccg ttacttctta
    13021 ggtaacgaac aagcataggg caagcagaaa agggaacttt tttcaacgaa aacatcagaa
    13081 gaggactggt attcaggaaa taaagcagaa gtgaaggtgt ttttcatgaa ttggaataaa
    13141 aaaaagacat aacacggata ttgtcatttt ccgcctgtta tgcctgcatt tgattcattt
    13201 tccgaaatta atttcatttt tgtttgcgta ttttcataaa tatgtccatc tttgcgccat
    13261 gaatcattcc gttacctaag aagtaacgca caccgataaa cactgtatat caagcttcta
    13321 aatcagatac actgacctac tccgcaccgc tttacgtaag acaaattcat cc
//
