LOCUS       c00003_gnlPro..        24857 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CLNOEFCN_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 11:23:42
            Original ID  :: gnl|Prokka|CLNOEFCN_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 5712065
            Orig. end    :: 5736922
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..24857
                     /aStool="rule-based-clusters"
                     /contig_edge="False"
                     /core_location="[5722065:5726922]"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      10001..14857
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /neighbourhood="10000"
                     /product="TPP_fatty_acids"
                     /protocluster_number="1"
     cand_cluster    1..24857
                     /candidate_cluster_number="1"
                     /contig_edge="False"
                     /detection_rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /kind="single"
                     /product="TPP_fatty_acids"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..24857
                     /candidate_cluster_numbers="1"
                     /contig_edge="False"
                     /product="TPP_fatty_acids"
                     /region_number="9"
                     /rules="(TPP_enzyme_C and (minimum(2, [ACD1_car,
                     ACP_syn_III_C, AcetylCoA_hyd_C, AcetylCoA_hydro,
                     Acyl-CoA_dh_1, Acyl-CoA_dh_2, Butyrate_kinase,
                     CT_Propionyl_CoA1, CT_Propionyl_CoA2, CT_Propionyl_CoA3,
                     Carboxyl_trans, CoA_trans, CoA_trans_230_acto,
                     CoA_trans_2_CAF, CoA_trans_6_Glutaconate, E1_dh, ECH_1,
                     ECH_2, HBT, HBT_2, HCDH, HpaB, Ketoacyl-synt_C, Thiolase_C,
                     Thiolase_N, adh_short, adh_short_C2]) or FA_synthesis) and
                     not (PFL-like or PFL_6_pcresol or PFL_9_tma or Gly_radical
                     or Gly_430_pcre or PFL_acetate1 or PFL_acetate2 or
                     Gly_radical_scatole or PFL_proline or PFL_toluene) and not
                     (POR or POR_N))"
                     /tool="gutsmash"
     CDS             complement(1038..3008)
                     /locus_tag="ctg3_4832"
                     /transl_table=11
                     /translation="MLKDKLTLDLSFMLSSVKEQNMTSQGLYYNPLVPLYLFPAGDDFS
                     KVQAYQRYDSERNLLTQYWPYSTSLALQNPYWITEHIKIPNHKNRYMATASAKYEFADW
                     INVTARAKMDRNNERRERMYDAGTNTLFASKYGYYSKSNIENQQIYGELLLNINKYFVD
                     NTLNVTANVGGNFENNDYQSDYFGGKLKSVANLFTFGNVDTSEKNLANQYGYHLKKRAI
                     FGSAQIGYKSMAYLDVTARNDWSSTFKGTNTGSFFYPSIGLSGIITDIFRCSTDIMPYM
                     KVRISYSEVGNSPDVFLAIPTYALVDGVPVTQSRRPNPNLKPERTKSWEAGFNFVFFKN
                     RLRLDGSIYQSRTYNQFFERTLSSTTGYKSEVVNGGRVDNKGIELSLRFEDKWGNFGWS
                     SYLTYSLNRNKVVELLRNYEDPYTHELTSLDRIDMGGTSMYKMILTEGGSIGDIYVNTL
                     RTDEHGAIYVHPSDQVVVTQPDEFVKAGNSAPKYNLGWGNTFSYKGLSLGFLFTARVGG
                     VVVSQTQATMDAYGSSKATAIARDNGGAIVNGRPIGAEDYYTKIGGAGAQGGIGSMYTY
                     SATNVRLAELSLGYDIPINKYVDWIKGLNVSFIGKNLFFLYRKAPFDPELTASTGTYFQ
                     GIDMFMSPSLRNLGFSVKVNF"
     CDS             complement(3333..3992)
                     /locus_tag="ctg3_4833"
                     /transl_table=11
                     /translation="MVIGRDRCYDIFRSNGLCQRTSRKRPRTTNSNHNYYIYPDLLNVA
                     PKFVATRLGAMVVADITYVNTGQGWAYLSLLTDASSRAIVGYALYKTLETEGPLKALEM
                     AISFYEKYHIDMSTLIHHSDRGVQYCSNKYVERLKEHQINISMTQCGDPLHNALAERMN
                     NTIKNGWLFDCDDESFEQVSKRIEDAVYVYNHVRPHQGINMRTPMEVVSETGGLTA"
     CDS             complement(4226..4609)
                     /locus_tag="ctg3_4834"
                     /transl_table=11
                     /translation="MKYSKKQYNYYSDDERMSYIREYLSSPESKSEFCKRHGFCAKLLT
                     YWLNKYQIEDKDMGRSSKPVNSDAIDSSISELQKELSLLRAENRKLHRALADESLRHEA
                     CEELINLAESTYHIKVRKNSDAK"
     CDS             complement(4650..5927)
                     /locus_tag="ctg3_4835"
                     /transl_table=11
                     /translation="MRISLALLFAVVLQLSAENGYAQRTHVAISMNNVSVEQVLNKIEE
                     ASDYVFLYNDKTIQKNRIVSVRNKSGKILDILDDIFKGTDITYTVVDKQIILSTNKMQL
                     VQQEGQIQIKGVVKDAGGDPLIGVNVKVKDSTVGTITDINGNFTLQTRKGDILEISYVG
                     YATKTVKVQNAQVLNIVLTEDTEVLNEVVVTALGIKKEAKSLSYNVQQVSNAEITRIAD
                     ANFVNNLNGKVAGVTINSSSAGVGGSSRVVMRGTKSLNGNNNALYVVDGIPMSDMSAAS
                     TQPTDSYEGAGQSGDPISGLNPEDIESISVLSGPSAAALYGSAAANGVVMITTKKGREG
                     RTSVSISNNTTFSAPLVLPEFQNTYGQTEVGSYYSWGSKLNTPSSYDPKDFFQTGVNVT
                     NAASLSTGTDKNQTYLSLGTTNAKGM"
     CDS             complement(6177..7091)
                     /locus_tag="ctg3_4836"
                     /transl_table=11
                     /translation="MNPESLLRKAQALGEDIKEMESIDVMGAYQQAQTQIKTNRRRSMY
                     NQLMRYVAFLTIPLLLSSLILGYLYWGATDTEEKYAEVMAATGSVIRYELPDHSVVWLN
                     SGSTLRYPTVFKKDNRNVELKGEAYFEVEADRKRPFYVNTPAGLSVYVYGTKFNVNAYE
                     DDNSIETVLEKGKVNVISPDGKTTVQLAPGERLLYNKVDQKLLKGKVDVYEKVAWKDGK
                     LIFRNAELGEIFKRLARHFNVDIQFNNISGKEYKYRATFRNETLPQILDYLAKSAALKW
                     RTEEAVQQADDTFTKKKIIVDLY"
     CDS             7326..7895
                     /locus_tag="ctg3_4837"
                     /transl_table=11
                     /translation="MKISFSRQTKERAFKQLYEDYYAPFCLYAKRFVDDKEVREDIVSD
                     VFTSLWDKLDTDSFDLQSETALGYIKMCVKNSCLNFLKHQEYEWSYAENIQKKAPLYET
                     ETDSVYTLDELYRMLYETLNKLPENYRTVFMKSFFEGKTHAEIAEEMNLSVKSINRYKQ
                     KTMELLRNELKDYLPLFLLFLSPEQL"
     CDS             complement(7869..8972)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) AMP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1025:AMP-binding enzyme (Score: 52.9; E-value:
                     7.5e-17)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_4838"
                     /sec_met_domain="AMP-binding (E-value: 6.9e-15, bitscore:
                     52.9, seeds: 145, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIFDRQKQRLLLEGKEYTPGDIHSLVAEGEGNHPSAIWDLYLFLN
                     EWFNDDPVITVHTSGSTGAPKELLVRKDQMIQSARLTCEFLDLKQGETALLCMNLRYIG
                     AMMVVVRSLIAGLNLIVRRASGHPLADVDTPLRFAAMVPLQVYNTFQIPEEKEKLKQTE
                     ILIIGGGAVDKALEEKIRNLSNAVYSTYGMTETLSHIALRRLNGAAASDRYYPFSSVEL
                     FLSSENTLMINAPLVCDDTLQTNDIARIYPDGSFTILGRKDNVINSGGIKVQAEEIERL
                     LQSSIPVPFVITSVPDRRLGQAVTLLIEGQMEISALGTKLESVLASYYRPKYIYTVNHI
                     PQTGNGKINRKECRVLAESLQLLGRQE"
     CDS             complement(8972..9997)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MR_MLE_C"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_4839"
                     /sec_met_domain="MR_MLE_C (E-value: 2.1e-27, bitscore:
                     94.5, seeds: 401, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDCKIDIIPRVLHFKQPAGTSRGTYTTRKVWYLHFTAPEFPNWVG
                     IGECAPLPNLSCDDLPDYEEVLAKICRQVENQGGKLDMEALCKYPSILFGLETAIRHFF
                     EGSWALWDTPFSRGEAGIPINGLIWMGDFNRMLAQIEKKMEAGFRCIKLKIGAINFEEE
                     LALLQHIRSHYSSKEIELRVDANGAFSPTDAMEKLKRLSELDLHSIEQPIRAGQWEEMA
                     RLTSESPLPIALDEELIGYNTWEEKQRLLSAIRPQYIIIKPSLHGGLAGGEEWIAEAEK
                     LNIGWWITSALESNIGLNAIAQWCATFQNPLPQGLGTGLLFTDNVEMPLEIRKDCLWFC
                     K"
     CDS             complement(10001..10825)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: ECH_1"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_4840"
                     /sec_met_domain="ECH_1 (E-value: 9.7e-80, bitscore: 265.8,
                     seeds: 9, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTQREWTTIREYEDILFDYYNGIARITINRERYRNAFTPTTTAE
                     MSDALRICREEADIDVIVITGAGDKAFCSGGDQNVKGRGGYIGKDGVPRLSVLDVQKQI
                     RSIPKPVIAAVNGFAIGGGHVLHVVCDLSIASENAIFGQTGPRVGSFDAGFGASYLARV
                     VGQKKAREIWFLCRKYNAQEALDMGLVNKVVPLEQLEDEYVQWAEEMMLLSPLALRMIK
                     AGLNAELDGQAGIQELAGDATLLYYLTDEAQEGKNAFLEKRKPNFKKYPKFP"
     CDS             complement(10829..12496)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: TPP_enzyme_C"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_4841"
                     /sec_met_domain="TPP_enzyme_C (E-value: 2.7e-06, bitscore:
                     25.6, seeds: 323, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYSDKKNILQLVALLEAHGITKVVLCPGSRNAPIVHTLSTHPGFT
                     CYAMTDERSAGYFAIGLALNGGHPAAVCCTSGTALLNLHPAVAEAYYQNIPLVVISADR
                     PAAWIGQMAGQTLPQPGVFQTLVKKSVNLPEIQTEEDEWYCNRLVNEALLETNHHGKGP
                     VHINIPISEPLFQFTVESLPEVRVITRYQGLNVYDRDYNDLIERLNRYQKRMIIVGQMN
                     LIYLFEKRHTKLLYKHFVWLTEHIGNQTVPGIPVKNFDAALYAMPEEKTGQMTPELLIT
                     YGGHVVSKRLKKYLRQHPPKEHWHVSADGEVVDLYGSLTTVIEMDPFEFLEKIAPLLDN
                     RVPEYPRVWENYCKTIPEPEFGYSEMSAIGALIKALPESCALHLANSSVIRYAQLYQVP
                     STIEVCCNRGTSGIEGSLSTAVGYAAGSDKLNFIVIGDLSFFYDMNALWNINVRPNLRI
                     LLLNNGGGEIFHTLPGLDMSGTSHKYITAVHKTSAKGWAEERGFLYQRVENEEQLAEAM
                     KTFTQPEAMEQPVLMEVFSNKNKDARILKDYYHQLKQK"
     CDS             complement(12516..13628)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Chorismate_bind"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_4842"
                     /sec_met_domain="Chorismate_bind (E-value: 1.5e-55,
                     bitscore: 186.9, seeds: 119, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDEKSNLTTIDALIQRKQPFAVYRVPGEKYPRLLTEDVGAVRLI
                     FDLKELNGQRGFVIAPFRIDKSCPIVLIQSDRTGQPLPMEIVAEEEQDLQSYPEESFHT
                     LCTGKYATCFHTFIEALRDATFDKLVLSRSLTIGKNPEFSPSAVFRAACQRYIHSYIYL
                     CYTPQTGVWLGSTPEIILSGEKNEWNTVALAGTQPLQNGKLPQVWDDKNRQEQDYVASY
                     IRRQLLSLGIRSTESGPYPAYAGALSHLKTDFHFSLKDNKNLGDLLKVLHPTPAVCGLP
                     KEEAYRFILENEGYDRKYYSGFIGWLDPEGRTDLYVNLRCMHIEDEQLTLYAGGGLLAS
                     SELNDEWQETEKKLQTMRRILVSAPIMMNH"
     CDS             complement(13625..14857)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     TPP_fatty_acids: HBT"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_4843"
                     /sec_met_domain="HBT (E-value: 1e-14, bitscore: 53.0,
                     seeds: 132, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKYKLLVLDVDGTLLNDAKEISKRTLAALLKVQQMGVRIVLASGR
                     PTYGLMPLAKSLELGNYGGYILSYNGCQIINAQNGEILFERRINPEMLPYLEKKARKNN
                     FALFTYHDDTIITDTPENEHIQNEARLNNLKVIKEEEFSVAIDFAPCKCMLVSDDEEAL
                     VSLEGHWKRRLNGALDVFRSEPYFLEVVPCAIDKANTLGALLEELDVKREEVIAIGDGV
                     CDVTMIQLAGLGVAMGHSQDSVKVCADHVTASNEEDGVALAVEKAIIAEVRAAEIPLDQ
                     LNAQARHALMGNLGIQYTYADEDRVEATMPVDHRTRQPFGILHGGATLALGETVAGLGS
                     MILCQPDEIVVGMQVSGNHISSAHEGDTVRAVATIVHKGRSSHVWNVDVFTSTNKLVSS
                     IRVVNSVMKKR"
     CDS             complement(14942..15304)
                     /locus_tag="ctg3_4844"
                     /transl_table=11
                     /translation="MVQVRIKRVYEDFSETDGYRVLVDKLWPRGIKKEWLKYDYWAKDI
                     TPSAALRRWFHEDIPGHWNDFVVMYQKELEASQAVADFLTLIKPHPVITLLYASKEPVY
                     NHARILRDYLEMHLKE"
     CDS             complement(15416..17143)
                     /locus_tag="ctg3_4845"
                     /transl_table=11
                     /translation="MKSIRSVICFCLFLFVFNQLLFADKTIENDSLYTSEYISRIYMAE
                     PERALSLLDGAESKKTIPLRIIHELRSRVYRNMYMTKLAFLYAKKSYLLDSVSQKDPKH
                     LLTMTVDLAELAVLMSDHKESMRYALDGIKLAQKEKDKGAESKLLFCIGENKWQLSFKE
                     EAYDYFDKAIKLLQGTSSKLEMAMLSYFYGMKMDYLLNDSRSKEALEVGLKREKLLKDI
                     AKLPEKTKGFLDLQYTYLYAKMSYICYLEGKYDQAEKYYQQYLSTENSQTPDGKTYAIP
                     YLLVSKQYQKVVDQCQDFKKLMQEQDTVNLQYISILQKEVKAYKGLKDFEKVAALRESI
                     ISIIDGINSKDKQNAALELNAIHKADEQEEYIAEQTLQLRIRNISLAFLGCVTCLILFV
                     LWRIWRHTIIVKYKNKMLAKFINEKLAGKVENKQLFIDGDAEDPIAVPLDLEPETGFSE
                     KDDLSPDEVVESREEEDENKKIFKELNRIVVQDQLYLSPELSREDLAQIVHLNNARFAR
                     MIKENTGTNFNGYINELRINYAIQLLKQHPNYTIRAIADEAGFNSTPILYSMFKKRLV"
     CDS             complement(17521..18288)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Acetyltransf_1"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_4846"
                     /sec_met_domain="Acetyltransf_1 (E-value: 1.7e-05,
                     bitscore: 23.4, seeds: 223, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEAKYITLTKENIEKEHICCAFSDKKCKDSYELKKTWLKNEFENG
                     YVFRRLDERAKVFIEYGPAEKAWVPVNAPNYLMINCFWVSGKYKGCGHGKALLQSAVED
                     AKAQGRDGLVTVVGTSKFHFMGDAKWLLRQGFETIEKLPYGFSLLALKINSAAPDPSFN
                     GTVSSGECEEKEGVVVYYTHRCPFAEFHVRNSLVSVTENKGIPLKIVRLETMAQAQNAP
                     TPATIFSLFYKGKFVTTDLSACMEQRFDKALGL"
     CDS             complement(18624..19874)
                     /locus_tag="ctg3_4847"
                     /transl_table=11
                     /translation="MKKNIRYNIVLLLLMVEAVLIPAFTQMPEIKQGQSISFEEYLNRV
                     GKKNLSYLAEKLNVSIADAEVIARKIFPDPELGFEAGNETFSLGVSYSLEMGNKRGARI
                     KLARTQAELEKLVLQQGFQDLRAEAADLFLEAILQRELLEVQKSSYEYMYQLSQSDSLR
                     YVSGEITENDVRQSKLETVTLLNTVYSQEAAYHSALVLLNKHMGMSADTLHIPLGNWEE
                     LSRDFALSDLVKAGLDNRIDLLVAQKSTEVTTREYKLTRAERRPDIGVSVSYERNWNGF
                     LPPSRSATAGVSVPLTFSNINKGAVKAAKFRIGQSEIMERDMELQIQAEITQAWFNYEA
                     EKKKIAQYKAGVLEDSQKVLDGMVYKYKRGETSILDVLVAQRTYNEVQQEYLETMKGYA
                     ASLVALERACGIWDICF"
     CDS             complement(19852..22308)
                     /locus_tag="ctg3_4848"
                     /transl_table=11
                     /translation="LNRGDLGYVVRGIGLIGNLDDLGHIVVSTTSGVPVFLNDIGSLKY
                     GNLERKGVLGYTDRTRNYSESLEGIVLLLKHENPSKVLEDIHVAVDELNNETLPEGVRI
                     HTFLDRTNLVDTTLSTVSHTLLMGMALVVLVLILFLGNWRGALLVSITIPVSLLIAFIL
                     MHLTDIPANLLSLGAIDFGIIVDGAIVMLETILKKREDNPKQYLEEKSMAQRAKEVGRP
                     ILFSTIVIITAYLPLFAFERVERKLFTPMAFTMSYAMIGALLVALLLIPGLAYAIYRKP
                     HKIYKNKWLDRLKDKYIRTITGFLEAPLKAIIPSGLILTAGIVLSVVVGKDFLPELDEG
                     SIWLQVNLPPGISVEKSRELSDTLRARTMKYSEVTYIMVQAGRNDDGTDPFTPSHFEVS
                     IGIKPYDEWPKGKTKKDLIHELEEEYKLLPGFKVGFSQPMIDGVMDKIAGAHSELVVKV
                     YGEDFRETRRIAEEITKALGTVRGAVDLDIDQEPPLPQLQISMNRDAIARYGLNVSDVA
                     DLIEVAVGGKAIAQLYQGDRQYGITCKYKEEARNTPEKIAGLMLTSSTGAKIPLSQVAD
                     VRLSVGESTITREMNRRHLTVKLNLRGRDLTSFLNEAQNTINEKVHYDKNKYTIKWGGA
                     FENQKRAYTRLAVIIPLTLTGMFILLYVTFGKFRQAGLVLAIVPLALFGGMLALNVRGM
                     TLNVSSAVGFIAMFGLSIQNGIIMVSQVNGLRRGGMELRKSVIEGARQRFRPILMTSVT
                     TILGLFPASLATGIGSDVQRPLATVIVYGLMFSTFISMFLLPVFYYLVENNVLNKKKND
                     EKEYTI"
     CDS             complement(22305..22958)
                     /locus_tag="ctg3_4849"
                     /transl_table=11
                     /translation="MKKELMLSIIQKRWVMLCLFVMMCIFGYYSWKQLSIEAYPDIADV
                     TSQVVTQVPGLAAEEVEQQITIPLERAINGLPGMHVMRSKSTFGLSMITIVFKDGTEDY
                     WSRQRVQERLNEVELPYGAVPGLDPLTSPVGEVYRYIIESDQHSLRELTDLQNWVIIPR
                     IKEVSGVADVTNFGGITTQFQVEVDPSKLEQYNLSLSQVVEAIENNNANVGEAC"
     CDS             complement(22965..24074)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Biotin_lipoyl_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_4850"
                     /sec_met_domain="Biotin_lipoyl_2 (E-value: 2.9e-07,
                     bitscore: 28.6, seeds: 52, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMMKRELHTFIIGSVLFFTACGDKQESEQKSGYRIQGDTVYIADP
                     LLLEKIKVSVSELKPYSKKVITSGVVRPIPPRYAYVAPPFAGRVTKSYVRIGQSVRQGT
                     PLFEISSPDFTSAQKEYFQALSSRELAKKDLKRKEDLIRNGVSSQRELEEAQNALLIAD
                     KEFENASAALRVYQVDNPAEMILGQPMIVRSPIPGEVIKDNIVTGQYLKDDTEPIAIVA
                     DLSKVWIAAQVKEKDIRFINEGSSLDIEISALPGTVIKGNVYHVEEEVDEETRSIQVLS
                     VCDNLNGHLKLGMYTTVHFLSVPVGQIQIPEKALLQGEKDSYVFVQIAPLVFVRTSVTV
                     ETTENGIAVISEGLRPGDKIISEGGYYLK"
ORIGIN
        1 ccttgataat tgctcatatt gcttgttgtg ataccaatac gtacgccatg atattcaccg
       61 tcatcggctg ctgtaaaata agagctgatt cgcgaatcat tcagtccgtt caaataggct
      121 acgatggtag cacccggacg acagtcaccc gaattgaagt tataggcaat ctcgtgcaac
      181 ggatgatgat attccaatga attatgcgaa agttcggcac gttccgcttt actttcgata
      241 aagccgaaca tgttttccat cgacttcttt gcctgtgctt ctgccagtgt gggattcgca
      301 tatgaaacac gtatagcaag acgcaaacgc agtgtgttgg cgaacttcac ccacttctct
      361 acgtcccccc catatacaca gtcatagtca ctcatcagct tagcatccac atttccgttc
      421 acataattgc tcaatacttc gatagcatta tccagttctt caaaaaactt attataaacc
      481 aaatccaatg cgtcatataa gctggaagag ccatagttta catatggaat aggaccaaat
      541 gtatcagcaa tacggtgcat gccttctacc tttacgatgg tagccaatgc gtcaacttcc
      601 ggcagttcct gttcagtggc tattttgtga atactttgcc atggtgccat aattccggta
      661 taggcataat caaaagtggc attcacccat tgttcctgaa agttatactg cccgttatga
      721 ttggtagatc ctaaggtagc ggcaatatag cccgaataaa ggtcatgcga taagttctga
      781 gcaatctgat agtcagagtc gagcttgtcg ccatcattta tgattacaac ccgacgcagc
      841 atttgcgaaa agaaagcacc cgtcttcaag ttgtctactt ccatcatttc ctcggtgact
      901 tcattcggat ttacgttatc ctcatagtcg atacacgaaa tgttatttaa tagcatcaaa
      961 gatatcccga gaatggaaag tttgttccat gatagtattt tatttaatat catatcttct
     1021 acaatttata agtttgatta gaaattaact ttcacagaga atcccaaatt acgcagactt
     1081 ggcgacataa acatgtcgat accttgaaag taagtgcctg tacttgctgt cagttccgga
     1141 tcgaacggag cttttctata aaggaaaaag agattcttac cgatgaaaga tacgttcaac
     1201 cccttaatcc agtccacata cttgttgata ggaatatcat agcctaacga taactcagcc
     1261 aaacggacat tagtcgcact gtaggtgtac atagaaccaa taccaccctg agcacctgca
     1321 cctccaattt tcgtatagta atcttccgca ccgattggac gaccgttaac aatggctccg
     1381 ccattatcac gggcaatagc tgtagccttt gaagagccgt atgcgtccat cgtcgcctgt
     1441 gtctgtgata caactacacc accgacacgt gccgtgaaca ggaatcccaa tgaaagccct
     1501 ttgtaactga atgtgtttcc ccaaccgagg ttatacttag gagcactatt accagccttt
     1561 acaaattcat caggctgagt aactacaacc tggtccgaag gatggacata gatagctcca
     1621 tgttcgtccg tgcgaagcgt attcacataa atatcgccga tagatccgcc ttctgtcagt
     1681 atcattttat acatacttgt cccgcccata tcaattctat ccaaagaagt aagttcgtgc
     1741 gtataaggat cttcatagtt gcgcagcaat tccaccactt tatttcggtt caatgaatag
     1801 gtcagatacg aactccagcc aaaatttccc catttgtcct caaaacgcaa agacaattcg
     1861 atacctttat tatctacacg accgccattg actacttccg atttatagcc ggtagtagaa
     1921 gaaagggtac gttcaaagaa ctgattgtag gtacgtgact gatagataga tccatccaat
     1981 ctcaaacggt tcttgaagaa gacaaagtta aatccggctt cccatgattt ggtacgttcc
     2041 ggcttcagat tggggttagg acgtcgggac tgagtaacag gaacgccatc aaccaacgca
     2101 taagtcggaa tagccagaaa tacatccggt gaattaccta cttccgaata agaaatacgt
     2161 actttcatgt atggcataat atccgtactg caacggaata tatctgtgat aatccccgaa
     2221 agaccgatag acggatagaa gaaagaaccg gtattcgtcc ctttgaaggt agatgaccag
     2281 tcgttacgag ccgtcacatc cagataagcc atagacttgt aaccgatctg agcactaccg
     2341 aatatggcgc gttttttcaa atgatagcca tattggttgg ccagattctt ctctgaagta
     2401 tccacgttgc caaaagtaaa gaggttggct accgacttca gtttgcctcc gaaataatca
     2461 gactgataat cattgttttc aaagttccca cccacattag ctgttacatt tagggtatta
     2521 tcgacaaagt acttattaat attcagcaat aattcaccgt atatctgttg attctcgata
     2581 ttactcttgg agtaataacc gtatttagaa gcaaacaaag tatttgttcc ggcatcatac
     2641 atgcgctcac ggcgttcgtt gttgcggtcc attttggcac gggctgttac attaatccag
     2701 tcagcaaatt catattttgc cgatgcagtt gccatataac ggttcttatg attaggtatt
     2761 ttaatatgct cggtaatcca gtatggattc tgtaaagcca gacttgtgct gtaaggccag
     2821 tactgagtca gtaaatttcg ttccgaatca taccgctgat atgcctgtac tttggagaaa
     2881 tcatctcccg caggaaatag ataaagaggt actaacgggt tataataaag tccctgagag
     2941 gtcatatttt gttcttttac agagctaagc ataaaactca ggtcaagagt cagcttatct
     3001 ttcagcatct tggcaacatt acgaacagtg acattgtaac gttcgtagtc attattatgg
     3061 ataatactga tgtgtactgg ttttagttga caacttcgtt tgttataact gaattagttt
     3121 actcaatata ctttaatatc taaataggtt tacttttgtt attcttattc ctatgttagt
     3181 tgtcttttgt tggtgcttgc aaatttatgc atcttccttt atttacgcaa gccttcttca
     3241 ggaaaatgta atgttgccaa caaccaaata ctcttcggtc ggggatcgcc ctagcggcaa
     3301 ggggcgggac cacccgtccc gacgagcggg tattatgctg ttaatcctcc cgtttcgctg
     3361 accacttcca taggtgtcct catgtttatc ccttgatgag gccgcacatg attatataca
     3421 tatacagcat cttcaatgcg cttgcttact tgctcgaagc tctcatcatc acagtcgaat
     3481 agccaaccgt ttttaatggt gttgttcatt ctttcagcca atgcattatg taaaggatca
     3541 ccacactgcg tcatactgat gttgatttga tgctctttaa gcctctctac atatttattt
     3601 gagcaatatt ggacaccccg gtcggaatga tgaataagag tgctcatgtc tatgtgatac
     3661 ttctcataga atgatattgc catctccaaa gctttcaagg gcccctccgt ctcaagagtt
     3721 ttgtaaagcg catatcccac gatggcacga cttgacgcat cggtaagcaa cgagaggtaa
     3781 gcccagccct gaccggtgtt tacgtaggtt atatccgcca ctaccatagc gcccaatctt
     3841 gtagcgacaa atttgggtgc aacattcaac agatcggggt agatatagta attatggttc
     3901 gaattcgttg ttctaggacg cttgcgactt gtacgttgac acaaaccatt ggagcgaaaa
     3961 atgtcataac aacgatcacg accgataacc atctttggtc caaacttact cacgcagcag
     4021 gcgtataact cgcgcatacc agctttgggc atgagttcca acagttcttt gcagtacaac
     4081 acgatgcttg tggtaaggat atcaacctcc aaatgtcggt tcacatgctt gtaataacct
     4141 tgtcgggtta tgccgaagta atcacagagg aactttatac aaccacgttt gcgtcggggt
     4201 gagtgcctct gtgacaaggt gtcgattact tggcatcgga gttttttcgt accttgatat
     4261 gatacgtgga ttcagcaaga ttgatgagtt cttcgcacgc ctcgtgacgt aaactctcat
     4321 cagcaagagc ccgatgaagt ttacggttct cagcacgcaa tagcgatagt tctttctgga
     4381 gctcagaaat actagaatca atagcatcgc tatttactgg tttagaggat ctacccatat
     4441 ctttgtcttc tatttgatac ttgttaagcc aataagtaag aagcttggca caaaagccgt
     4501 gacgcttaca aaactcagat ttgctctcgg gacttgataa atactcacga atataagaca
     4561 ttcgttcatc atcactgtaa tagttgtact gctttttcga atatttcatc tttattttcg
     4621 atttttgaag tgtcaactta ttcagtacac tacatacctt tggcattggt agtacctaaa
     4681 gataagtaag tctgattctt gtcagtacct gtagaaagac tggcagcatt tgttacattc
     4741 acacctgtct gaaagaagtc tttaggatca tagctgctcg gcgtattcaa tttactgccc
     4801 cagctgtagt aactacccac ttctgtctgc ccataagtat tttgaaattc gggcaagaca
     4861 agaggagcgg agaaagtcgt attattggat atgctgactg aagtacgtcc ttccctacct
     4921 tttttagtag taatcatcac aacaccattg gcagcggcac taccgtaaag agctgcagct
     4981 gacggtccac tcaaaacaga gatactctct atatcctcgg gattcagacc ggaaatagga
     5041 tcaccggact gaccggcacc ttcgtatgag tccgtaggct gtgtagaagc ggcactcata
     5101 tcactcatcg ggataccatc aaccacataa agagcattgt tattaccatt caatgatttg
     5161 gttccacgca tcactacacg tgaagagcca ccgacaccag ctgaagatga gttaattgta
     5221 acacccgcaa ctttaccgtt cagattattg acgaagttgg catctgcaat gcgtgtaatc
     5281 tcggcattgc ttacttgctg tacattgtat gacaaagatt tagcttcctt cttgataccc
     5341 aatgcagtaa caacgacttc attcagtact tctgtatctt ctgtcagcac aatattcaga
     5401 acttgggcat tctgtacctt tactgttttc gtggcatatc ccacataaga aatttccaga
     5461 atatctcctt tcctggtctg tagcgtaaag tttccgttta tatcggtgat agtaccgacc
     5521 gtagaatctt tcactttcac attcacaccg atcaagggat ctccgccagc atctttcaca
     5581 actcctttta tttggatttg tccttcctgc tgaacaagtt gcattttatt agtcgataaa
     5641 ataatctgct tgtcaactac ggtatacgta atatcggtcc ccttaaaaat atcatctaga
     5701 atatccagaa tcttacctga tttatttctc acagaaacaa tacgattctt ctgaatcgtt
     5761 ttgtcattgt aaaggaaaac ataatcggaa gcttcttcta ttttattcag tacctgttct
     5821 acagatacat tgttcataga aatggcaaca tgcgtccgtt gagcatagcc attctctgca
     5881 gatagttgta aaacgactgc aaaaagtagt gccagactaa tcctcataac taaaggtagt
     5941 tttagattta aagcatattt aggatataat gcaataaatg aatgattttt tttcatacat
     6001 ttgcggttaa ctaaagttta ttactataat gaactgtggt ttgattccgg ttagcgtttg
     6061 caagactcct taccgcgaat ctgaaaaatt gggggaagac agctgttggt agcagctttc
     6121 ttcctttttt tacgatcttt gtgttatctc ataggctatt ctcattttta tggttactaa
     6181 tataaatcta ctattatctt tttctttgtg aatgtatcat ctgcctgttg taccgcctcc
     6241 tcagttctcc acttcaaggc agcagactta gccagataat ccaatatctg tggcagtgtt
     6301 tcattacgga aggtcgcacg atatttatat tcttttcccg atatattatt aaactgaata
     6361 tctacattaa aatgccgtgc cagccgtttg aatatttcac ccaactcggc attgcggaat
     6421 atcaacttac cgtctttcca tgccaccttt tcataaacat ccacttttcc cttcaacaat
     6481 ttctgatcta ccttattata aagcaatcgt tctcctggag ctaactgaac tgttgttttt
     6541 ccgtccggtg aaataacgtt tactttaccc ttttctaata ccgtttctat actattatca
     6601 tcttcgtaag cattcacatt aaatttggtt ccgtacacat agacacttaa cccggcagga
     6661 gtattgacgt aaaaaggccg tttcctgtcc gcttctactt caaaataggc ttcacctttt
     6721 aattcaacat tacgattatc tttcttaaaa acggtaggat aacgtaaagt actaccggag
     6781 tttaaccaga caaccgaatg gtcaggaagt tcgtaacgaa tgactgaacc tgtagccgcc
     6841 atgacttctg catacttctc ttcagtatcc gttgctcccc aatataaata tcccaaaatc
     6901 aaagaagaaa gtaataaagg tatagtcaag aatgcaacat aacgcatcaa ctgattatac
     6961 atactccttc ttctgtttgt ctttatttgg gtctgtgctt gttgataggc acccattaca
     7021 tcaatagact ccatttcctt aatatcctct cctaatgcct gcgcttttcg gagcaatgat
     7081 tccggattca tattttccat attctctttc aaaatcttat cttttaattg caattacact
     7141 aatagtacaa ctgaggtaat cgaaaaggga caggtataac atactttttt tttattttat
     7201 tttttaagct atcttatttt ccacagcttc ataccaaaaa caaaaaaaga aagaaaattt
     7261 taggaaatgc tgattttctt attatatatt tgcagtaaaa tgaaaaacta cagaatctca
     7321 aaataatgaa aatatctttt tccagacaga ctaaagaaag agctttcaaa caactttacg
     7381 aggattatta tgcccctttc tgcctgtatg caaaaagatt tgtagatgat aaagaagtcc
     7441 gcgaggacat tgtttcggat gtattcacct ccctatggga caagttggat accgactctt
     7501 tcgatttgca atcagagaca gcattgggat atataaaaat gtgtgtaaaa aacagctgtt
     7561 tgaactttct gaaacatcag gagtatgaat ggagttatgc cgaaaatatc caaaagaaag
     7621 ctcctctata tgaaacagaa acagatagtg tatatacact tgatgagtta taccgaatgc
     7681 tatacgaaac attaaataag cttccggaaa actatcgcac cgtatttatg aaaagtttct
     7741 ttgaaggcaa aacacatgcg gaaattgccg aagaaatgaa tctcagcgta aaatccatta
     7801 atcggtataa acaaaaaaca atggaactcc tgcggaacga gttgaaagat tacctcccgc
     7861 tgtttttatt attcctgtct cccgagcaac tgtaagctct ctgctaaaac acggcactct
     7921 ttacgattaa tcttcccatt tcccgtttga ggaatatgat ttaccgtata aatatattta
     7981 ggacgataat aagatgctaa gactgattcc aatttagtcc ctagcgcact tatctccatc
     8041 tgcccttcta tcaataaagt aacagcctgc cccaaacgcc gatccggaac ggaagtgatc
     8101 acaaacggta cagggataga cgactgaagt aacctttcga tctcttctgc ctgcacttta
     8161 attcctccgc tattgattac attatccttt cttcccagaa tcgtaaaact accgtccgga
     8221 taaatgcggg caatatcatt tgtctgcaga gtatcatcgc aaacaagcgg agcattaatc
     8281 atcaaagtat tttctgaaga caaaaacaac tctacggatg aaaaaggata ataacgatcg
     8341 gatgctgctg cgccattcag acggcgaaga gcgatgtgag aaagggtttc cgtcatcccg
     8401 taagttgaat aaacagcatt ggacagattt ctgatttttt cctctaaagc cttgtcaact
     8461 gctccgcctc ctataattaa aatctccgtt tgctttaatt tctctttctc ttcgggtatc
     8521 tgaaatgtat tatacacctg caaaggcacc atagccgcaa accttaaagg agtgtccaca
     8581 tctgccaatg gatgaccgga agcccgacgt actataagat tcaacccggc aatcaaagaa
     8641 cggacgacta ccatcatcgc cccgatatag cgaaggttca tacacaataa tgccgtttca
     8701 ccctgcttta aatccagaaa ctcacaagtc aagcgtgcac tctgtatcat ctgatctttg
     8761 cgaacaagca attctttagg tgcccccgta gaaccggaag tatgtacagt gatcacagga
     8821 tcatcattaa accattcgtt tagaaaaaga tacaagtccc atatagcaga agggtggttt
     8881 ccctcacctt ctgctacaag gctatgtata tcgcccggag tatattcctt tccctccagc
     8941 aacaaacgct gtttttgtcg gtcgaatatc atcatttaca aaaccacaaa caatcttttc
     9001 tgatttcaag aggcatctct acattatctg taaagagtaa cccggtgcct aacccttgcg
     9061 gcaatggatt ctgaaaagta gcacaccatt gagcgatagc attcagaccg atattagact
     9121 ccagagcaga agttatccac caaccgatat tcagtttctc cgcttctgca atccactcct
     9181 cgccaccggc taatccgcca tgaagagaag gtttgataat aatatattgc ggacggatag
     9241 ccgaaagtaa tctttgcttt tcttcccagg tattatagcc tatcagttcc tcatccaaag
     9301 ctatcggcaa aggagattcg gaagtaagac gtgccatttc ttcccattgt ccggcacgaa
     9361 tgggctgttc tatcgaatgt aagtccagtt cggacaagcg tttcaatttc tccatcgcat
     9421 ctgttggtga gaatgctccg ttggcatcta cacgcaattc tatttcttta gaagaatagt
     9481 gagagcggat atgttggagt aaagccagtt cttcttcaaa gttgatggca ccgatcttca
     9541 actttataca gcggaatccc gcctccatct tcttctctat ctgagcaagc attctattga
     9601 agtcacccat ccagataagc ccgtttatcg gaatacctgc ttccccacgt gagaagggtg
     9661 tatcccacaa agcccagctt ccttcaaaaa agtgacgaat ggctgtctcc aagccaaaaa
     9721 ggatggaagg gtacttgcat agagcttcca tgtccagctt acctccctga ttctctacct
     9781 gccggcagat tttagccagc acttcctcgt aatcgggaag atcatcacag ctaagatttg
     9841 gcagaggagc gcactccccg atccctaccc aattgggaaa ttcgggagca gtaaaatgaa
     9901 gataccagac ttttcgcgtt gtgtatgtgc ctcgtgaagt tccggccggc tgcttgaaat
     9961 gaagcacccg cggaataatg tctattttgc aatccattgt ttaagggaac ttcggatatt
    10021 tcttaaagtt aggtttacgt ttctccagaa atgcattctt tccttcctga gcctcatccg
    10081 tcagatagta aagcaaggtc gcatcccctg ccagctcctg aatacctgcc tggccgtcca
    10141 gttcggcatt caatccggct ttaatcatcc gcaaggccaa cggactgagc agcatcattt
    10201 cttccgccca ttgcacatac tcatcctcca gttgctccaa tggaactact ttattcacca
    10261 atcccatatc caacgcttcc tgcgcattgt atttccggca aaggaaccat atctcacgtg
    10321 ccttcttctg accgacgaca cgagccagat aagaggctcc gaaacctgca tcaaagctac
    10381 ctacgcgagg accggtctgt ccgaagatcg cattctccga agcaatcgat aaatcgcaaa
    10441 ctacatgaag cacgtgtccg ccaccaatgg caaatccatt tacggcagca attaccggtt
    10501 tcggaatgct gcggatttgt ttctgtacat ccagaacact cagacgggga acaccgtcct
    10561 tgccgatata gccgccacgc cctttcacat tctggtcacc gcccgaacag aaagccttgt
    10621 caccagctcc cgtaatcacg atcacatcaa tatccgcttc ttcccggcaa atgcgcaatg
    10681 cgtcactcat ttcagccgtt gtagtcggag taaatgcatt tcgatagcgt tcacggttaa
    10741 tggtgatgcg ggcaatccca ttatagtaat caaagaggat atcttcgtat tctctgatgg
    10801 ttgtccattc tctttgtgtt gacataatct atttttgttt tagttgatga taataatctt
    10861 tcagtatacg tgcatcttta tttttattgc tgaatacttc catcagaacc ggttgttcca
    10921 tggcttccgg ttgtgtgaag gttttcatcg cttcggcaag ctgttcttca ttctctaccc
    10981 gttgataaag gaatccgcgt tcttccgccc atcctttggc agatgtcttg tgaacggctg
    11041 taatatactt gtgcgatgta cccgacatat ccagtccggg taatgtatgg aaaatctccc
    11101 ctcctccgtt attcagcaaa agaatgcgta gattgggacg gacattgatg ttccacaaag
    11161 cattcatatc ataaaagaaa ctaaggtcac ctataactat aaaatttagt ttatccgaac
    11221 cggcggcata tcccactgcc gtggacaacg agccttcgat gccgcttgta ccccgattac
    11281 agcatacctc aatcgtagaa ggaacctggt ataactgagc atagcggata acagaactat
    11341 ttgccagatg caatgcacat gattccggca atgcttttat caaagcaccg atagccgaca
    11401 tttccgaata tccgaactcc ggttcgggaa tggtcttgca ataattctcc catacacggg
    11461 gatactccgg cacgcggtta tccagcaatg gagctatttt ctccagaaac tcaaacgggt
    11521 ccatttcgat gacggtagtc agagaaccgt aaaggtcaac cacttctcca tcagcagaca
    11581 catgccaatg ttctttaggc ggatgctgcc gaagatattt tttcaaccgc ttggaaacca
    11641 catgtccgcc ataagtaatc aataactcgg gagtcatctg gccggttttc tcttcgggca
    11701 tcgcataaag cgccgcatca aaattcttca ctggaatacc gggtactgtc tgattaccga
    11761 tatgctcggt cagccacacg aaatgtttat ataacaattt ggtatgccgt ttctcaaaca
    11821 agtaaatcaa gttcatctgt ccgacaataa tcatccgctt ctgatatctg ttcaagcgtt
    11881 cgatcaggtc attgtaatcc cggtcgtata cattcagccc ctgatagcgc gtaatgacac
    11941 gtacttcggg aagcgactcc accgtaaact ggaacaaagg ttcggatata ggaatattaa
    12001 tatgtaccgg accttttcca tgatggttgg tttccagcaa ggcttcattc accaagcggt
    12061 tacagtacca ttcatcctct tctgtctgaa tctccggaag gtttaccgac ttcttcacca
    12121 atgtctgaaa aacaccgggc tgcggcaatg tctgtcccgc catctgtcca atccaggcag
    12181 caggccgatc ggcagagata acaactaaag gtatattctg ataatacgct tctgccacag
    12241 caggatgaag attgagcaac gctgtaccgg aagtacagca aacggcagca ggatgcccgc
    12301 cattcagcgc aagaccaatc gcaaaataac cggcactccg ttcatccgtc atagcataac
    12361 aagtaaaacc cggatgagta gacagcgtat gcacaatagg tgcattacgg ctaccgggac
    12421 ataacactac tttcgtaatt ccatgcgcct caagcagcgc gaccaactgg agtatatttt
    12481 tcttgtccga atacatattg atagtgatta gcttgttagt gattcatcat tattggagca
    12541 gacacaagaa tacgcctcat ggtctgcaat ttcttttccg tttcctgcca ttcatcattc
    12601 aactctgaag aggctaacaa tccgccaccg gcatacagtg tcaattgctc gtcttcaatg
    12661 tgcatgcaac gcagattcac atacaaatct gtgcgtccct ccggatcgag ccaaccgata
    12721 aaaccggaat aatacttacg atcgtaccct tcattttcca aaatgaaccg gtaggcttct
    12781 tctttaggca gtccgcacac ggcaggagtc ggatgcagga ctttcagaag gtctcccaga
    12841 tttttattat ctttcaaaga gaaatggaaa tcagttttca gatgtgacaa ggcaccggca
    12901 taagccggat aaggtccgct ctctgtggag cgaatgccca gcgaaagaag ctgccgacgg
    12961 atataggacg ccacataatc ctgctcctga cggtttttgt catcccatac ttgcggaagt
    13021 ttaccattct gcaaaggttg agttcctgcc agggcaactg tgttccattc atttttttcg
    13081 cccgacaata taatttcggg ggtacttccc agccacacgc ccgtctgagg agtataacac
    13141 agatagatat aggaatgaat ataacgttga caagctgcac gaaaaacagc tgaaggggaa
    13201 aactccggat tctttccaat agtgagacta cgggaaagca ccagtttatc aaaggtagca
    13261 tcacgcaagg cttcaataaa tgtatgaaaa caggtcgcat acttcccagt acaaagggta
    13321 tgaaaagatt cctccggata actttgcaag tcctgctctt cctctgccac gatttccata
    13381 ggcaacggtt gtccagtcct gtcggactgt atcaacacaa tcggacatga cttatctata
    13441 cggaacggag caatcacaaa tcctctttgt ccattcagtt ctttcaaatc gaaaatcaag
    13501 cggacagctc cgacatcttc tgtcaacaga cgaggatact tctccccggg aacacgataa
    13561 acagcaaagg gctgtttccg ctgaataagt gcatcaatag ttgtcaagtt acttttttcg
    13621 tcaatcatct ttttttcatc acactgttga ccacccgtat agaggacacc agtttattgg
    13681 ttgaagtaaa aacgtccaca ttccatacat gggaggaacg tcctttgtgt acaatcgtcg
    13741 ctactgcacg tactgtatca ccttcgtgcg cagaagatat atgatttccg ctgacctgca
    13801 ttcctaccac aatttcatcc ggctgacaga gaatcatcga gccgagtccg gcaactgttt
    13861 ctcccaatgc aagcgtagct ccaccgtgca aaataccgaa cggctgacgg gtacggtgat
    13921 ctaccggcat cgtcgcctct acacggtctt cgtcggcata tgtatattgg atacccagat
    13981 tacccatcaa tgcgtgacgc gcctgtgcat tcaactggtc caaaggaatc tctgcagcgc
    14041 gaacttccgc tattatcgcc ttttcgacag ccagagccac tccgtcttcc tcattggaag
    14101 ctgtcacatg atccgcacag acctttaccg aatcctgcga atgccccatc gccactccca
    14161 gtcctgccag ctgaatcatc gttacatcgc acacaccgtc tcctatagcg atgacttctt
    14221 cacgcttcac atccagttct tccaataaag ctcccaatgt gttggcttta tcaatcgcac
    14281 acggcactac ttccagaaaa taaggttcgg aacggaaaac atccaaagct ccgttcaacc
    14341 gtctcttcca gtgtccttcc agactaacca acgcttcctc gtcatcgctg acaagcatac
    14401 acttacacgg agcaaagtca attgctacag aaaattcctc ttccttgatc actttcaaat
    14461 tattcaagcg agcttcattc tggatatgtt cattctccgg agtgtcagta atgatcgtat
    14521 catcatggta agtgaacagt gcgaaattat tttttcttgc cttcttttcc agataaggca
    14581 acatttccgg attaatcctc cgctcaaaca gtatttctcc gttttgagca ttaattatct
    14641 ggcaaccatt ataagaaagg atataacctc cataatttcc gagttctagg gatttggcta
    14701 aaggcatcag accgtaagtc ggtcggccgg atgccaacac gatacgtact cccatctgct
    14761 gaactttcag caaagcagcc aatgtacgtt tactaatttc ttttgcatca ttgagaagcg
    14821 ttccgtctac atcaagaact aataatttat acttcatgga cacacgattt tgatttagat
    14881 tacaaaggta ggaaattgag tgaacgactg aaagcggaaa gagataaaaa ttactttaat
    14941 ttcactcttt cagatgcatt tccaaataat cacgaaggat tcgggcatga ttataaaccg
    15001 gttctttgga tgcataaagc aaagtgatca ccggatgagg tttgataaga gtcagaaaat
    15061 cggcaacagc ttgagaagct tccagttcct tctgatacat tacgacaaaa tcattccagt
    15121 gacccggaat atcttcatga aaccatctgc gcagtgctgc ggaaggcgtt atatcttttg
    15181 cccagtaatc atatttcaac cattcttttt tgattccacg tggccagagt ttatctacca
    15241 gcacccgata tccgtcggtc tctgaaaagt cttcgtacac tcgctttatc ctaacttgca
    15301 ccatttccgt ttatatttag ttatcataag aataaaccga taaaacggaa aattgtttat
    15361 cgaaaaagcc aaaatcaacc taaggattcc tgcgtttttt taaattcgta aggagtcata
    15421 ccagtctttt cttgaacata ctgtacagaa taggcgtact attaaatccg gcttcatcag
    15481 ctatcgcacg aatggtataa ttgggatgtt gcttcaataa ctgaatcgca tagttaatac
    15541 gaagttcatt aatatacccg ttgaaattag ttccggtgtt ttccttgatc atccgggcga
    15601 aacgcgcatt attcaaatgt acaatctgag ccagatcctc tctcgacaat tccggagaca
    15661 gatataactg atcctgaaca acaatacgat tcagttcttt gaaaattttc ttattctcat
    15721 cctcttcctc cctactctcc actacttcat ccggagataa atcgtctttt tcggaaaagc
    15781 cagtttccgg ttccaagtct aatggaacag ctatcggatc ttccgcatct ccatctatga
    15841 ataattgttt gttctctact tttccagcca gtttctcatt gataaacttt gccagcattt
    15901 tgtttttata tttaacaata atcgtatgac gccaaatccg ccatagcaca aataaaatga
    15961 gacaagtgac acatcccaaa aaagcaagtg atatgtttct gattcttaac tgtaaagtct
    16021 gttcggcaat atattcttcc tgctcgtcag ctttatgaat agcatttaat tccaaagccg
    16081 cattctgttt atccttgctg ttaataccat caataataga aataatagac tcacgtaatg
    16141 ctgctacttt ttcaaaatcc ttcaagcctt tataagcttt cacctctttc tgaagaatac
    16201 taatatactg caagttgaca gtatcctgct cttgcatcaa tttcttaaaa tcctgacatt
    16261 gatcaacgac tttctgatat tgtttagaca ctagcagata aggtatcgca taggtttttc
    16321 catccggtgt ctgtgaattc tctgttgaca aatattgttg ataatatttt tccgcctgat
    16381 catactttcc ttccagatag cagatatacg acatttttgc atacaagtaa gtatattgca
    16441 gatcaagaaa gccttttgtt ttttccggta atttagctat atctttaagt agcttttcgc
    16501 gcttcaaccc aacctccaat gcttctttac tacgggaatc attgagcaga taatccattt
    16561 tcatcccata aaagtatgaa agcatagcca tttccaattt ggaacttgtg ccttgaagca
    16621 atttgatagc tttgtcaaaa tagtcatatg cctcctcttt gaaagacaat tgccatttat
    16681 tttcaccaat gcaaaacaac agcttacttt cagccccttt atccttttct ttttgtgcta
    16741 gcttgatacc atcaagagca tacctcatac tctctttatg gtcactcata agcactgcta
    16801 attctgccag gtcgacagtc atggtcaaca agtgcttagg atctttctga gaaacggaat
    16861 ccagcaaata agactttttg gcatacaaaa aagctagttt agtcatatac atattacgat
    16921 aaaccctgct gcgtaattca tgtataatac gcagagggat agtcttctta ctttcagctc
    16981 catccaacaa acttaaagcc cgttcaggtt ctgccatata aattcgactt atatactcac
    17041 tggtatatag cgaatcattc tctatagttt tgtcggcgaa aaggagctgg ttaaacacaa
    17101 acaaaaacaa acaaaaacaa ataaccgagc gaatactttt cattataatc ccaatgattt
    17161 tactccccaa aagtaaaaca tagtttcata aaatgcaaga attgaacata tttgaatgaa
    17221 ctaaaataag aaaagttagt gattataaaa gtcaggagcc atcaagtttt cccaccaacc
    17281 acatacaata aaatactaaa aatcaagcat atgtcacata cataaaacaa aacatctcaa
    17341 catataaata aactgccgat tctattaatg aatctgcata agatcagagc agcacatgaa
    17401 aaatcgaacc gaccagtcta aataaacacc agacaattat taacccgcca cactcatcag
    17461 agcaaaacag cacaaaaaca gaaaatcaaa aaagagaaac acatactgta ataagaaaga
    17521 ttataatccc aacgctttat caaaccgttg ctccatacat gcactcaaat ccgtcgttac
    17581 aaactttcct ttatagaaaa gagaaaagat agtagcaggt gtaggtgcat tttgtgcttg
    17641 tgccatcgtt tccaatctga ctatcttcaa tggaatacct ttgttctcag tcacactcac
    17701 taaagaatta cggacatgaa actctgcaaa cggacaacga tgtgtataat aaacgactac
    17761 accttctttt tcctcacatt ctccacttga tactgttcca ttgaatgacg gatcaggagc
    17821 tgccgaattt atcttcaaag ccaaaagact gaaaccatag ggtagttttt ctatcgtctc
    17881 aaacccctga cgtaataacc atttcgcatc acccataaaa tgaaatttag aggtaccgac
    17941 cacagtcacc aagccatccc taccctgtgc tttggcatcc tcgacagcag actgcaatag
    18001 tgctttgcca tgcccgcatc ctttatattt tcctgaaacc caaaaacagt ttatcattaa
    18061 atagttaggt gcattaaccg gaacccaagc tttttcggca ggcccatatt ctataaatac
    18121 ttttgcacgt tcgtcaagcc gtctgaaaac atagccattc tcaaactcat ttttcagcca
    18181 tgtctttttc aactcatagc tatccttgca tttcttatcg gagaaagcac agcaaatatg
    18241 ttctttttcg atattctctt tagtcagagt gatatacttc gcttccataa tattctgttt
    18301 attagtatat aaattccggt tgtccatttt aactacagca aagatacaca atcgaaagta
    18361 ataaaacatt gtccagtctc gtcaaaatga cacagtagta cggattaaag ttcggaaaac
    18421 agataagtaa ataaacctga gtgacaaact tatcaaagaa cttattgacc actctgtgga
    18481 agaagtgatc aaaaaactcc ctaagaaaaa acaggaggaa tatcgcacaa tgatttaaca
    18541 taaagcgtga aaccgctgac tggtaaccat acaaatatcc ggctttgctg caattcacaa
    18601 tagtaaagcc ggatatttaa ctgtcaaaag catatatccc atataccaca agctctttcc
    18661 aatgctacta gtgaagcggc atatcctttc attgtttcca gatactcctg ttgcacttca
    18721 ttataagtac gctgggcaac cagtacatca agaatactcg tttctccccg tttgtattta
    18781 tataccattc cgtcgagcac cttctgcgag tcttcaagta caccggcttt atattgagct
    18841 atctttttct tttcagcctc atagttgaac caggcctggg ttatctctgc ctgtatctgc
    18901 aattccatat ctctttccat tatctccgat tggccaatcc gaaactttgc agcttttaca
    18961 gctcctttat ttatattcga gaatgtcaga ggaacagata caccggcagt agcagaacgg
    19021 gacggaggaa gaaagccgtt ccagtttctt tcataagaaa cagatactcc gatatcgggt
    19081 ctgcgttccg ctctcgtcag tttatattcc cgggtagtaa cttcagtact tttttgagca
    19141 acaagcaggt cgatgcgatt atccagtccc gctttgacca aatcagacag agcaaagtcc
    19201 ctgcttagct cttcccaatt tcccaaaggg atatgaagcg tatcagcact catccccatg
    19261 tgtttattca acaaaaccaa agcggaatga taagccgcct cctgactgta aacagtatta
    19321 agcaaggtga cagtttccag ttttgactgc cggacatcat tctccgtaat ctctcccgaa
    19381 acatagcgta aactatcaga ctgactcagc tgatacatat actcataaga acttttctgt
    19441 acttcaagta attcgcgctg aagaattgct tctagaaaaa ggtcggcagc ctccgccctc
    19501 aaatcctgaa agccctgttg caggaccagt ttctccaatt ctgcctgagt ccgcgccaac
    19561 ttaatacgtg ctcccctttt atttcccatt tctaatgaat aggaaactcc caacgagaaa
    19621 gtctcattac ctgcttcaaa tcccaactcc gggtccggaa agattttccg ggcaattact
    19681 tccgcatcag caatactcac attgagtttt tcggctaaat aactcagatt ctttttccct
    19741 acccgattca gatattcttc gaaagaaata gactgcccct gctttatttc aggcatttgc
    19801 gtaaaagccg gaatgagtac ggcttccacc attaacagca agagcactat attatatcgt
    19861 atattctttt tcatcgttct tctttttatt taaaacattg ttctcaacca gataatagaa
    19921 aaccggaagc agaaacatag agataaaggt tgaaaacatc aatccataca caatcactgt
    19981 tgccagcgga cgctgtacgt cactaccgat tccggttgcc aacgaagccg ggaaaagtcc
    20041 gagtatcgta gtgaccgaag tcatcagaat aggtcggaaa cgctggcgtg ccccttctat
    20101 gaccgatttc cggagttcca ttcctcccct gcgcagccca ttgacctgcg ataccatgat
    20161 aattccattt tgtatggaaa gcccgaacat cgctataaat cctacggcag aagatacatt
    20221 cagcgtcata ccacgcacat taagagcaag catacctccg aaaagtgcca gaggaacaat
    20281 agccaatacc agtcctgcct gccggaactt cccgaacgtg acataaagca gtataaacat
    20341 ccccgtcagt gtcagcggta taatgacagc aagacgtgta taagcccgtt tttgattttc
    20401 gaaggcccct ccccatttga tggtatattt attcttgtca taatgtactt tctcattgat
    20461 cgtattctgg gcttcattca gaaaagatgt caggtcacga ccgcgcaaat tcagctttac
    20521 cgtcaaatgg cgtctgttca tttccctggt aatcgtactt tcgccgacac tcaatctgac
    20581 atcggcaacc tgagaaagag gtatctttgc accggtggaa gaagtcaaca taagtccggc
    20641 tattttctcc ggagtattcc gcgcttcctc tttatactta caggtgatgc catactggcg
    20701 gtcaccctga taaagttgtg cgatagcttt acctccgaca gccacttcaa tcagatccgc
    20761 tacatcggat acatttaatc cgtaacgagc tatggcatca cgattcatac tgatctgtaa
    20821 ctgtggcaag ggtggttcct gatcaatatc cagatcaaca gcccctcgca cagttcctaa
    20881 tgccttggtt atttcttcgg caatacgacg tgtttcacga aaatcttcgc catatacttt
    20941 caccaccagt tcactatggg ccccggctat cttatccatc accccgtcta tcataggttg
    21001 gctaaatcct actttaaaac cgggaagtaa cttatattct tcttccagtt catgaatcaa
    21061 atccttttta gtttttcctt tcggccattc atcataaggc ttaataccga tggacacttc
    21121 aaaatgtgaa ggggtgaacg gatcagttcc gtcgtcattc cttcccgcct gtaccataat
    21181 ataagttact tcggaatact tcatcgtacg ggcacgcaaa gtatcggata actcccgtga
    21241 cttttctacg gaaattccgg gtggcagatt aacctgtaac catatcgaac cttcatccag
    21301 ctccggaagg aagtcttttc ctacgacaac actcaacacg atccccgctg tcagaatcag
    21361 tcctgatgga atgatggctt ttaagggagc ttccagaaat cctgtaatgg tacgaatgta
    21421 tttatccttt agtctgtcca gccatttatt cttatatatt ttatgtggtt tacgatagat
    21481 tgcataggca agtcccggaa tcaataagag cgcaaccaac agtgctccaa tcattgcata
    21541 gctcatcgta aatgccattg gagtaaaaag tttgcgttca acacgttcaa aggcaaacag
    21601 cggaaggtat gccgtaataa tgacaatggt tgagaaaaga ataggccgcc ccacttcttt
    21661 ggcgcgttgc gccatgcttt tttcttcgag atattgtttg ggattatcct cacgtttctt
    21721 aaggatcgtt tccagcataa cgatagcgcc gtccacaata ataccaaaat caatagcacc
    21781 aagcgacaga aggttagccg gaatatccgt cagatgcata agaataaaag cgataagcaa
    21841 tgacacagga atcgttatag ataccaataa tgcaccacgc cagttgccta gaaacagaat
    21901 aagcacaaga accaccaaag ccatacccat cagcaaggta tgggatacgg tactcaaagt
    21961 agtatccacc aagttggtac gatccagaaa agtatgtatc ctcactcctt ccggcaatgt
    22021 ctcattattt aactcatcaa ctgccacatg aatatcttcc agtactttag acggattctc
    22081 atgtttcaga aggagtacga ttccttccag actctcagag tagttgcggg tacggtccgt
    22141 atatcccagc actccctttc tttcaagatt tccatacttc aaagaaccta tatcattcag
    22201 aaagacagga actccggaag tagtactcac tacaatatgt cccaaatcgt ccaaatttcc
    22261 gattaatcca attccccgta ccacataacc caagtcacca cgattcaaca cgcttccccc
    22321 acattggcat tgttattctc aatggcttca acaacctggc tgagagataa attatattgt
    22381 tccagtttgg acggatctac ttcaacctgg aactgagtag tgatcccacc gaaattggtt
    22441 acatcagcca ctcccgacac ttccttgata cggggaataa ttacccagtt ctgaaggtcg
    22501 gttaattcgc gtaatgagtg ctggtcactt tctatgatat aacggtacac ttctcctacg
    22561 ggagatgtca gcggatcaag tcccggaaca gctccataag gcagttctac ttcattcaat
    22621 ctttcctgta cgcgctggcg gctccagtag tcctctgtcc cgtccttaaa gacaatggta
    22681 atcattgaca gcccgaatgt actcttactc cgcatgacgt gcataccggg cagcccatta
    22741 atagcgcgtt ccaaaggaat ggttatctgc tgttccactt cctccgcagc cagtccggga
    22801 acttgagtga ccacctggga agtgacatct gcaatatccg gatatgcttc tatcgaaagc
    22861 tgtttccatg agtaatatcc aaagatacac atcatcacaa acaggcaaag cattacccat
    22921 cttttttgta taattgaaag cattaattcc ttcttcataa tttcttactt taaataatat
    22981 cctccttcac tgattatctt atctccggga cgcaatcctt cgctgatcac cgctattccg
    23041 ttttctgttg tctccactgt caccgacgtc cgtacgaaaa ccaacggagc aatctgcaca
    23101 aatacatagc tatccttttc gccctgcagt aacgctttct ccgggatttg aatttgtccg
    23161 accggaacac tcagaaagtg gacagtagtg tacatcccca gcttcagatg tccgttcaaa
    23221 ttatcacaga ccgaaagtac ctgaatggac cgggtttcct cgtctacctc ctcctctaca
    23281 tgatacacat tgcctttaat aaccgtaccg ggcaatgccg aaatttcaat atccagacta
    23341 ctgccttcat ttataaaccg gatatctttc tcctttacct gagccgcaat ccatacctta
    23401 gacaggtcgg caacaatagc tatcggttcg gtatcgtctt tcagatattg ccctgttacg
    23461 atgttatcct ttatcacttc cccgggaata ggagaacgaa caatcatcgg ttgccccaat
    23521 atcatttccg ccggattgtc cacctgatat acccgcaatg cggcagaggc gttttcaaac
    23581 tccttatctg ctatcaataa agcattctgg gcttcttcca gttctctttg cgaactgaca
    23641 ccattcctta tcagatcttc tttgcgtttc aaatcttttt tagcaagttc cctggacgaa
    23701 agtgcctgaa agtattcctt ttgtgcagaa gtaaagtcgg gggaactgat ttcaaataaa
    23761 ggtgttccct gacgtaccga ctgtccgata cgcacataag attttgtgac tctccctgca
    23821 aatggaggag caacataagc ataacgggga ggaatgggac gcaccacacc ggacgttatc
    23881 accttcttgg aatagggttt cagttcagac actgatactt tgatcttttc aagtaaaaga
    23941 ggatctgcaa tatagaccgt gtcaccttgt atacgatagc cacttttttg ctctgattcc
    24001 tgtttatccc cgcatgcggt aaaaaacaac acactgccaa taataaatgt gtgtaactct
    24061 ctcttcatca tcataattaa acataagtta agttagtaac cggatttccg ggtacaaaga
    24121 tagacggctc ccttcggaga gcctgttaga gaatagttag aatcctatta gaatcttatt
    24181 agagtaaata aagatttctt cttaaaacag cagctttgtt gttagagagt acgcacaaat
    24241 aaggggttga ctaaaaagcc aacccttcaa cggatgatat tccggtattt ttatcgtaag
    24301 ccgaaaagtt cttattcttt cacacaacgt atactttgag caaaaccttg atatgacaat
    24361 ctgaaattat gagaattata tgcagactca agcgaccagg ctccataacg tattctcctg
    24421 tcataaggtg gattctgcaa ttccgatctc atataaggag gacctacact tgccgaccaa
    24481 tagtatccgg tactacccct actttccaaa gcaccacttg tgttattcag acgaccggct
    24541 gacggaaaaa agacagatgc attcgttccg gaatcgggat taaaatacaa tactccctga
    24601 taagcaacat tactatttcc taatgatacg ccatagtttc cattcgaagc ctcttttatc
    24661 ggacgtctgt cgaaaaatcc gtccgaataa aatgtataag ttgttccttt tagttgtttc
    24721 cgggcaagca tatctttgtt tgctccgtaa ggatatgtcc caggacctgt attaccagtt
    24781 ccaccaaaag gagtagtaaa agctgtagcg tagtctgcac ttgaagccgc atttcctgca
    24841 aaaggtacat taaataa
//
