LOCUS       c00003_gnlPro..        15217 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NCIMFKEH_3.
ACCESSION   c00003_gnlPro..
VERSION     c00003_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2024-10-04 12:06:04
            Original ID  :: gnl|Prokka|NCIMFKEH_3
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15217
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..915
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FeS"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Fer4"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_7"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_2"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_17"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1016:4Fe-4S dicluster domain (Score: 38.9; E-value:
                     3.3e-12)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_1"
                     /sec_met_domain="Fer4_7 (E-value: 2e-11, bitscore: 38.9,
                     seeds: 208, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4 (E-value: 8.6e-08, bitscore: 26.4,
                     seeds: 528, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_2 (E-value: 1.8e-07, bitscore: 25.6,
                     seeds: 214, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_17 (E-value: 3e-07, bitscore: 25.5,
                     seeds: 82, tool: rule-based-clusters)"
                     /sec_met_domain="FeS (E-value: 7.5e-10, bitscore: 32.9,
                     seeds: 364, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 9.9e-05, bitscore: 17.3,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNLILIAVISLGAIALVLAAILYVASKKFAVYEDPRIAQVGEVLP
                     QANCGGCGYPGCSGFADACVKAGSLDGKFCPVGGQPVMAQIADILGLAAGEAEPMVAVV
                     RCNGTCANRPRTNQYDGAKSCAIAASLYGGETGCSYGCLGCGDCVAACQFDAIHMNPET
                     GLPEVDEAKCTACGACVKACPKAIIEIRPQGKKSRRVYISCVNKDKGAVARKACTVSCI
                     GCGKCVKTCPFEAITLENNLAYIDPNKCKSCRKCVEVCPQNSIIELNFPPRKPKEEAPA
                     APKPATKVETPAAKATEAPKVTE"
     protocluster    1..15217
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[0:5217]"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      1..5217
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="2000"
                     /detection_rule="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /neighbourhood="10000"
                     /product="Rnf_complex"
                     /protocluster_number="1"
     cand_cluster    1..15217
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Complex1_51K and minimum(5, [FMN_bind,
                     FeS, Fer4, Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N,
                     SLBB]))"
                     /kind="single"
                     /product="Rnf_complex"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15217
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Rnf_complex"
                     /region_number="1"
                     /rules="(Complex1_51K and minimum(5, [FMN_bind, FeS, Fer4,
                     Fer4_9, NQR2_RnfD_RnfE, Rnf-Nqr, RnfC_N, SLBB]))"
                     /tool="gutsmash"
     CDS             940..2277
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Complex1_51K"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: RnfC_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: SLBB"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_10"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_2"
                     /sec_met_domain="Fer4_10 (E-value: 3.7e-08, bitscore: 28.0,
                     seeds: 59, tool: rule-based-clusters)"
                     /sec_met_domain="SLBB (E-value: 2.2e-15, bitscore: 50.9,
                     seeds: 67, tool: rule-based-clusters)"
                     /sec_met_domain="Complex1_51K (E-value: 6.5e-50, bitscore:
                     163.5, seeds: 88, tool: rule-based-clusters)"
                     /sec_met_domain="RnfC_N (E-value: 2.5e-28, bitscore: 92.6,
                     seeds: 53, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 7.6e-05, bitscore: 17.7,
                     seeds: 79, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLKTFSIGGVHPHENKLSAHQPIITAEVPAKAVILLGQHIGAPAK
                     PVVAKGDVVKVGTRIAEPAGFVSAAIHSSVSGKVAKIDTIVDASGYAKPAIFIDVEGDE
                     WEETIDRSTTLVKECELSAEEIVKKIADAGIVGLGGACFPTQVKLCPPPSFKAECVIIN
                     AVECEPYLTADHQLMLEHAEEIMVGVSILMKAVKVNKAFIGIENNKPDAIELMTKVASS
                     YAGIEVVPLKVKYPQGGEKQLIDAITKRQVASGALPISTGAVVQNVGTAFAVYEAVQKN
                     KPLFERVITVTGKSVAKPSNFLARIGTPMKQLIDACGGLPEDTGKVIGGGPMMGKALVN
                     IEVPTAKGSSGILIMNQKEAKRGEAQTCIRCAKCVSACPMGLEPYLLGALSENGDFETM
                     EKERIMDCIECGSCQFTCPANRPLLDYCRLGKGKVGAMIRARQAKK"
     CDS             2283..3290
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: NQR2_RnfD_RnfE"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_3"
                     /sec_met_domain="NQR2_RnfD_RnfE (E-value: 1.5e-117,
                     bitscore: 386.6, seeds: 472, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MENKLIVSLSPHVHGGDSVQKNMYGVLIALIPAFLVSLYFFGLGA
                     LIVTATSVAACLFFEWAIGKYLMKKPTTTICDGSAIITGVLLAFNLPSNLPIWIIILGA
                     LFAIGVGKMSFGGLGCNPFNPALAGRVFLLLSFLVQMTSWPVVGQLTAYTDATTGATPL
                     ALMKQAIHAADKSAAMDALNQIPDALSLLIGQNGGCLGEVSALALLIGLVYMLWKKIIT
                     WHIPVSILATVFIFAGIMHLADPEKYVSPILQLLSGGLMLGAVFMATDYVTSPMSKKGM
                     LIYGVCIGLLTVVIRLFGAYPEGMSFAILIMNAFTPLINTYCKPKRFGEVAKKK"
     CDS             3317..3778
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_4"
                     /sec_met_domain="FMN_bind (E-value: 4.7e-10, bitscore:
                     34.5, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVLTGVTAVSVALLAYVNELTKGPIAEANAKTLNEALKKVLPE
                     FTNNPVAESDTIFSEKDGKKNVDFIVYPAKNGEELVGTAVEAKSMGFGGELKVLVGFNA
                     EGKIYNYSLLAHAETPGLGSKADKWFGAYDPPRENRLCLMKRVKSLFWG"
     CDS             3775..4023
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: FMN_bind"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_5"
                     /sec_met_domain="FMN_bind (E-value: 1.1e-09, bitscore:
                     33.4, seeds: 891, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNPGEAPLTVSKDGGAVDAITASTITSRAFLNAVNAAYQAYKAEG
                     GKVNGVSGASQKATGADSDTATGATIKVELTDSVSAK"
     CDS             4056..4622
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_6"
                     /sec_met_domain="Rnf-Nqr (E-value: 1.2e-68, bitscore:
                     225.1, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMNGIIKENPTFVLLLGMCPTLGTTSSAINGMGMGLATMFVLICS
                     NVVISLIKNLIPDMVRIPSFIVVIASFVTLLQMVMQAYVPGLYATLGLFIPLIVVNCIV
                     LGRAEAFAAKNNAVASMFDGIGMGLGFTIALTLLGAVREFLGTGKIFDLTIMPEEYGML
                     VFVLAPGAFIALGYLIALINSFKKA"
     CDS             4645..5217
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Rnf_complex: Rnf-Nqr"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_7"
                     /sec_met_domain="Rnf-Nqr (E-value: 6.2e-62, bitscore:
                     203.2, seeds: 650, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEYILIFISAIFVNNIVLSQFLGICPFLGVSKKVETAMGMSAAVA
                     FVLTIATIVTFLIQKFVLDVFGLGYLQTITFILVIAGLVQMVEIILKKVSPALYQALGV
                     FLPLITTNCCILGVAILVIQKDYDLLTGVVYAFSTAIGFGLALVLFAGLREQMSLVKVP
                     KGMQGTPIALITAGLLAMAFMGFSGVV"
     CDS             5441..6475
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GDP_Man_Dehyd"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_8"
                     /sec_met_domain="GDP_Man_Dehyd (E-value: 6.7e-51, bitscore:
                     168.1, seeds: 258, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKERILVTGGTGYIGSHTVVELQNSGYEVIIIDNLSNSSADVVDN
                     IEKVSGIRPVFEKLDCLDFAGLDAVFAKYKGIKAIIHFAASKAVGESVQKPLLYYRNNL
                     VSLINLLELMPKHGVEGIVFSSSCTVYGQPDELPVTEKAPIKKAESPYGNTKQINEEII
                     RDTVASGAPINAIMLRYFNPIGAHPTALLGELPNGVPQNLIPYLTQTAIGIREKLSVFG
                     DDYDTPDGSCIRDFINVVDLAKAHVIAIRRILEKKQKEKVEVFNIGTGRGVSVLELING
                     FEKATGVKLNYQIVGRRAGDIEKVWANPDFANKELGWKAVETLEDTLRSAWNWQLKLRE
                     RGIQ"
     CDS             complement(6929..7555)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) GHMP_kinases_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_9"
                     /sec_met_domain="GHMP_kinases_N (E-value: 1.7e-09,
                     bitscore: 32.4, seeds: 447, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLAFPNIKINLGLSITEKRPDGYHNLETVFYPVALEDALEIRTSS
                     ETEKKIILHQYGMEIAGNPEDNLVAKAYSLLDKEFHLPPVEIHLYKHIPSGAGLGGGSS
                     DAAFMLKLLNDHFQLELSEEQLEVYAATLGADCAFFIKNKPTYAEGIGNLFSPIELSLS
                     GYQIMIVKPNVFVSTGKLFQIFIPTVRNIRSKRQSCVQLQNGRIS"
     CDS             7755..9317
                     /locus_tag="ctg3_10"
                     /transl_table=11
                     /translation="MAEQKRNTRNSKSTKIQPVNDYGRIQPQAPELEEAVLGALMIEKD
                     AYSLVSEILRPESFYERRHQLIYSAITDLAVNQKPVDILTVKEQLSKRGELEEVGGPFY
                     ITQLSSKVASSAHIEYHARIIAQKSLARELITFTSNIQSKAFDETLDVDDLMQEAEGKL
                     FEISQQNMKKDYTQINPVIDEAYKLIQKAAARTDGLSGLESGFTKLDKMTSGWQNSDLI
                     IIAARPAMGKTAFVLSMAKNIAVDYRNLVALFSLEMSNVQLVNRLISNVCEIESGKIKS
                     GQLAGYEWQQLDYKLKNLMDAPLYVDDTPSLSVFELRTKARRLVREHGVRIIIIDYLQL
                     MNASGMAFGSRQEEVSTISRSLKGLAKELNIPIIALSQLNRGVESREGIDGKRPQLSDL
                     RESGAIEQDADMVCFIHRPEYYKIYQDDRGNDLRGMAEIVIAKHRNGAVGEVLLRFKGE
                     FTRFSNPEDDMVIPMPGEPARAMLGSKMNTGDAGSMPPPPAPDFAPQTANPFGAPGDGP
                     LPF"
     CDS             9430..11892
                     /locus_tag="ctg3_11"
                     /transl_table=11
                     /translation="MNISYNWLKEYVNFDLTPDETAAALTSIGLETGGVEEVQTIKGGL
                     EGLVIGEVLTCTEHPNSDHLHITTVNLGDGEPVQIVCGAPNVAAGQKVVVATLGTKLYD
                     GDECFTIKKSKIRGVESTGMICAEDEIGIGTDHAGIIVLPETAVPGTLAKDYYNIKSDY
                     VLEVDITPNRADACSHYGVARDLYAYLIQNGRQATLQRPSVDGFKVENHDLNIEVKVEN
                     SEACPHYAGVIVKGVTVKESPEWLQNKLRLIGVRPINNVVDITNYIVHAFGQPLHCFDA
                     GKIKGNEVIVKTMPEGTPFVTLDEVERKLNERDLMICNKEEAMCIAGVFGGLDSGSTEA
                     TTDVFIESAYFHPTWVRKTARRHGLNTDASFRFERGIDPNGVIYCLKLAALMVKELAGG
                     TISSEIKDVFTTPAQDFIVDLAYEKVHSLVGKVIPVETIKSIVTSLEMKITNETAEGLT
                     LAVPPYRVDVQRDCDVIEDILRIYGYNNVEIPTTLNSSLTTKGEHDKSNKLQNLIAEQL
                     VGCGFNEILNNSLTRAAYYDGLEAYPSNHLVMLLNPLSADLNAMRQTLLFGGLESIAHN
                     ANRKNADLKFFEFGNCYYFNADKKNEEKVLAPYSEDYHLGLWVTGKKVSNSWAHADENS
                     SVYELKAYVENILKRLGLDLHNLVVGNLTDDVFAAALSVNTKGGKRLASFGIVTKKLLK
                     AFDIDNEVYYADLNWKELMKAIRSVKISYKEISKFPAVKRDLALLLDKNIQFAEIEKIA
                     YETEKKLLKEVELFDVYEGKNLEAGKKSYAVSFLLQDENQTLNDKMIDKIMSKLVKNLE
                     DKLGAKLR"
     CDS             11926..12666
                     /locus_tag="ctg3_12"
                     /transl_table=11
                     /translation="MGRAFEYRKAAKLKRWGHMAKTFTRLGKQIAIAVKAGGPEPENNP
                     TLRSVIATCKRENMPKDNIERAIKNAMGKDQSDYKSMTYEGYGPHGIAVFVDTLTDNTT
                     RTVADVRSVFNKFGGNLGTMGSLAFLFDHKCVFTFKKKDGLDMEELILDLIDYDVEDEY
                     EEDDEEGTITIYGNPKSYAAIQKHLEECGFEDVGGDFTYIPNDLKEVTPEQRETLDKMI
                     ERLEEFDDVQTVYTNMQPEEGEEE"
     CDS             12682..12921
                     /locus_tag="ctg3_13"
                     /transl_table=11
                     /translation="MFIRPRGTCSTNIELNVEDGVVKEVAFWGGCNGNLQGLSRLVRGM
                     KVADVITKLEGVRCGGRPTSCPDQLCRALHEMGY"
     CDS             13182..14435
                     /locus_tag="ctg3_14"
                     /transl_table=11
                     /translation="MKNIFQDLRRKDHKRYLGGLDVFKYIGPGLLVTVGFIDPGNWASN
                     FAAGSEFGYSLLWVVTLSTIMLIVLQHNVAHLGIVTGLCLSEAATKYTPKWVSRPILGT
                     AVLASISTSLAEILGGAIALEMLLDIPIIWGAVLTTLFVSIMLFTNSYKKIERSIIAFV
                     SVIGLSFIYELFLVEIDWPAATAGWVTPSFPKGSMLIIMSVLGAVVMPHNLFLHSEVIQ
                     SHEYNKKDDASIKKVLKYELFDTLFSMIVGWAINSAMILLAAATFFKSGIQVEELQQAK
                     SLLEPLLGSNAAIVFALALLMAGISSTITSGMAAGSIFAGIFGESYHIKDSHSQVGVLL
                     SLGIALLLIFFIGDPFKGLIISQMVLSIQLPFTVFLQVGLTSSRKVMGDYVNSRWSTFV
                     LYSIAIIVSVLNIMLLFS"
ORIGIN
        1 atgaatttga ttctgattgc agtgatttca ttgggagcta tagcgctcgt gctggccgct
       61 attctttatg tggcttccaa gaaatttgcc gtgtatgaag acccgcggat tgctcaggtg
      121 ggagaagtgc ttccccaggc taattgtggt ggatgtggct atcccggttg tagcggattt
      181 gccgacgctt gcgtcaaagc cggttcgctg gatggtaaat tctgccccgt aggtggacaa
      241 cctgtcatgg cacaaattgc tgatatcctc ggacttgcag ccggtgaagc tgaaccgatg
      301 gtagcagtgg taagatgtaa cggaacgtgt gccaatcgtc cgcgtaccaa ccaatatgat
      361 ggtgcgaaga gttgtgctat tgccgcttcg ctgtatggtg gggaaacggg atgtagttac
      421 ggatgtctgg ggtgtggcga ctgtgtggct gcttgtcagt tcgatgccat ccacatgaat
      481 cctgaaacgg ggcttccgga agtggatgaa gcgaaatgta ccgcttgtgg cgcctgtgtg
      541 aaggcttgcc cgaaagcgat catcgaaatc cgtccgcaag gaaagaagtc acgccgcgtg
      601 tatatctctt gtgtgaataa agacaaggga gctgtggcac gtaaggcttg tacagtgagc
      661 tgtatcggct gtggcaagtg tgtgaagact tgtccgttcg aggctattac gctggaaaac
      721 aatttggctt acatcgatcc gaacaagtgt aaatcttgcc ggaaatgtgt ggaagtttgt
      781 ccgcagaata gcattatcga gttgaatttc ccgccgcgga aaccgaaaga agaagctccg
      841 gctgctccga aaccggctac aaaagtggaa actcctgctg caaaggctac agaagctccg
      901 aaagtaacag aataataaca gaaaaaaata cagaactgta tgttaaagac attttcaatt
      961 ggtggagttc atccacacga aaataaattg tcggcacatc aacctattat cacagcggaa
     1021 gttcctgcaa aggctgttat tttgctgggg cagcatatcg gtgcgcctgc aaaaccggtt
     1081 gtagcgaaag gggatgtggt aaaggtaggc acacggattg ccgaacctgc cggctttgtt
     1141 tcggcagcaa ttcactcttc ggtcagtggt aaagtggcga agattgatac catagtcgat
     1201 gccagcggtt atgcgaaacc tgccatcttc attgatgtgg aaggcgacga atgggaagaa
     1261 acaatcgacc gtagcaccac actggtgaaa gagtgtgaac tttccgcaga agagatcgtg
     1321 aagaagattg ccgatgctgg aatcgtaggt ctgggcggtg cttgtttccc tacgcaggtg
     1381 aaactttgtc ctcctccttc tttcaaggct gaatgtgtga ttatcaatgc cgtagagtgt
     1441 gaaccttacc tgactgccga ccatcagctg atgctggaac acgcggaaga aatcatggtg
     1501 ggtgtttcta tcctgatgaa agcggtgaaa gtgaacaagg catttatcgg aatcgaaaat
     1561 aataagccgg atgctatcga actgatgacc aaagtggctt ccagctatgc aggtatcgaa
     1621 gtagtgccct tgaaggtgaa atatccgcaa ggaggtgaaa agcagctgat cgacgcgatt
     1681 accaaacgtc aggtggcgag cggtgcattg cctatctcta cgggagcagt cgtgcagaac
     1741 gtgggaacag catttgccgt ttatgaagct gtacagaaaa ataagccgtt gttcgaacgt
     1801 gtgattaccg tgacaggaaa gtcggttgcg aaaccttcca acttcctggc tcgtatcggt
     1861 acaccgatga aacagttgat tgacgcttgc ggtggtctgc ccgaagatac gggtaaggtg
     1921 atcggtggcg gtccgatgat gggtaaggcg ctcgtaaata tcgaggttcc tactgcgaag
     1981 ggcagttccg gtatcctgat tatgaatcag aaggaagcca aacgtggtga ggcgcagact
     2041 tgtatccgtt gcgcgaagtg cgtgagtgcc tgtccgatgg gactggaacc gtacttgctc
     2101 ggagccttgt ccgaaaacgg agattttgaa acaatggaaa aagaaagaat catggattgt
     2161 atcgagtgcg gctcttgcca gttcacttgt cctgccaacc gtccgttgct cgactactgt
     2221 cgtctgggca aaggcaaagt aggtgctatg attcgtgcac gtcaagctaa aaaataacga
     2281 atatggaaaa taaattaatc gtatcactat caccccacgt tcatggcgga gacagcgtac
     2341 agaaaaatat gtatggcgtg ctgatcgcac tgattccggc ttttctggtg tctctctatt
     2401 tcttcggact gggtgccctg attgtcacgg ctacttccgt tgcagcttgt ttgttcttcg
     2461 aatgggcgat cgggaaatat ttaatgaaga aacctaccac caccatctgc gacggctctg
     2521 ccatcatcac aggtgtgttg ctggcattca acttaccgtc taatctccct atctggatta
     2581 tcattctggg tgcactgttt gctatcggtg taggcaaaat gtctttcggc ggattaggtt
     2641 gcaatccttt taatccggca ctggcaggac gtgtgttcct gttgctttct ttcctggtac
     2701 agatgaccag ctggccggta gtcggacagt tgaccgccta tacggatgct accaccggtg
     2761 ccactccgct ggcattgatg aaacaagcga ttcatgctgc agataaaagt gcggctatgg
     2821 atgctttaaa ccagattccg gatgcattga gtttgctgat cggacagaat ggcggatgct
     2881 tgggtgaagt gagtgcattg gctctattga tcggactggt ttatatgctc tggaagaaga
     2941 tcattacctg gcatattcct gtgtctatcc tggctaccgt gtttatcttt gcaggtatca
     3001 tgcacttggc agatccggaa aaatatgttt ctccgatatt gcagttgctc tccggtggtc
     3061 tgatgctggg tgctgtcttt atggcaaccg actatgtgac ttctccgatg agtaagaaag
     3121 gaatgttgat ttatggtgta tgtatcggtc tgctgacggt tgtcattcgt ctgttcggtg
     3181 cttatcccga aggtatgtcg ttcgccatcc tgattatgaa tgcgttcact ccgctgatta
     3241 acacctattg taaaccaaaa cgctttgggg aggtagcgaa gaagaaatga aaaagttaga
     3301 atcatcttta aagaatatgt tgctggtact tacgggcgtg actgctgtct ccgtagcgtt
     3361 gctggcttat gtaaatgaac tgacaaaagg ccccattgcc gaagcgaatg cgaagacact
     3421 gaacgaggct ttgaaaaagg ttcttcccga atttaccaat aatccggtag cggaaagcga
     3481 tacgatcttc agcgagaaag acggaaagaa gaacgttgac tttatcgttt atccggccaa
     3541 aaatggcgaa gaacttgtag gaacggccgt cgaagctaaa tcaatgggat ttggcggcga
     3601 actgaaagta ctggtaggct ttaacgccga aggtaaaatc tataattact cgttactcgc
     3661 tcacgcggaa actccaggac tgggctctaa agccgacaaa tggtttggag catacgaccc
     3721 gccaagggag aacaggctgt gtctcatgaa gagagtaaaa agtctatttt ggggatgaat
     3781 ccgggtgaag ctccgttgac tgtcagcaaa gatgggggag cggtggatgc cattacagct
     3841 tctaccatta cttcacgtgc gtttctgaat gctgtaaatg ctgcttatca ggcttataag
     3901 gcagaaggtg gtaaagtgaa tggtgtcagc ggtgcttctc aaaaggctac aggcgcagac
     3961 tctgacactg ctacaggagc tacgataaag gttgaactta ctgattcggt cagtgctaaa
     4021 taagaaagga gacagatatg aataacttta aagtaatgat gaacgggatt atcaaagaga
     4081 atcctacgtt tgtactcctg ctcggtatgt gtcctacatt gggtacgact tcgtcggcca
     4141 tcaatggtat gggtatggga ctggctacca tgttcgtttt gatctgctcg aatgtggtga
     4201 tctctttaat caagaacctg attccggata tggtgcgtat cccgtcgttt atcgtggtga
     4261 tcgcgtcttt cgtaaccttg cttcaaatgg tgatgcaggc atacgtgccg ggactgtacg
     4321 ctacgctcgg acttttcatc ccgttgattg tagtgaactg tattgtgttg ggacgtgccg
     4381 aagcattcgc cgccaagaat aacgcagttg cttctatgtt cgacggtatc ggcatgggac
     4441 ttggtttcac cattgccctg acattgctgg gtgctgtccg tgaatttctg ggaaccggta
     4501 agattttcga tctgaccatc atgccggaag aatatggaat gttggtattt gtattggctc
     4561 cgggtgcttt catcgctttg ggatacctca ttgcgctgat taacagtttc aagaaagcct
     4621 aattcaatta aataagaaaa gaatatggaa tatatattaa tatttatttc ggcaatcttt
     4681 gtaaacaaca tcgtgttgtc gcagttcttg ggtatctgtc cgttcctggg cgtatctaag
     4741 aaagtagaga ctgcgatggg tatgagcgct gcggttgctt tcgtgttgac catcgctacc
     4801 atcgttacct tcctgattca gaagtttgtg ttggatgttt tcgggctggg atatttgcag
     4861 acgattacgt tcattctggt cattgccgga ttggtgcaga tggtggaaat cattctgaaa
     4921 aaagtatcgc ctgctctgta tcaggctttg ggcgtgttct tgcctttgat tacaaccaac
     4981 tgttgtattc ttggtgtggc tatcctggtg attcagaaag actacgacct gctgacaggt
     5041 gttgtgtacg cgttttctac ggccatcggt ttcggtctgg cactggtgct ttttgccgga
     5101 ttgcgcgaac agatgagcct cgtgaaagta cctaaaggaa tgcaaggcac tccgattgcc
     5161 ttgattaccg ccggtttgct tgctatggca ttcatgggat tctccggcgt ggtgtaagga
     5221 tttacagttg ataattaaat aggggattgg aagctctgct gtatggcgtc atacagcttt
     5281 gagtttccaa ttctttttta tacctgattg ccacccaatc gtacctaaat tacttttcag
     5341 caaataaaat tgtggcaaat tattgctatt ccattttatt tccatacatt tgtaactcaa
     5401 acaatgataa gccgagaaac taaccatttt tataaagtat atgaaagaaa gaattttagt
     5461 aacaggcggg acaggataca tagggtctca tactgttgta gaactacaaa acagtggata
     5521 tgaagtaatc atcatcgata atttatcaaa ttcaagtgcc gacgttgttg acaatataga
     5581 gaaagtttcc ggtattcgcc cagtttttga aaagctggac tgtttggact ttgccggtct
     5641 ggatgcagta tttgcaaaat ataaaggaat taaggcaatc attcactttg cagctagcaa
     5701 agcagtagga gagtcggtac aaaaaccgtt gctttactac cgtaataacc tggtttcttt
     5761 gattaacctt ctcgaactga tgccaaaaca tggagtagaa ggtattgtgt tctcttcttc
     5821 ttgtacagta tacggtcagc cggacgagct gccggtaacg gaaaaagctc cgatcaagaa
     5881 agcggaatca ccttatggaa ataccaaaca gatcaatgaa gagattattc gtgatacggt
     5941 agcttcaggt gctccgatca atgcgatcat gttgcgctat ttcaacccga ttggcgcgca
     6001 tcctactgca ttgctgggtg aactgcctaa cggggttcct caaaacctga ttccatatct
     6061 gacccagaca gccatcggta tccgtgagaa acttagcgtg tttggtgacg attatgatac
     6121 accggacggt tcttgtatcc gtgactttat caatgtcgtt gacttggcta aagcacacgt
     6181 gattgctatc cgtcgtatct tggaaaagaa acaaaaagaa aaagtagaag tatttaatat
     6241 tggtacagga cgtggtgttt ctgtattgga attaataaat ggctttgaaa aagccactgg
     6301 cgtaaaattg aattatcaga ttgtcggacg tcgtgcaggt gacattgaaa aagtttgggc
     6361 taacccggat tttgctaata aagagctggg ttggaaagcc gtagaaactt tagaagatac
     6421 tttacgctct gcatggaact ggcagctgaa actccgtgaa agagggattc aataaaagag
     6481 aaacttgttt taaataacat aaaagtttaa acaaatcgtg catgcgattt gtttatttga
     6541 tgctaatcga cctgaagctg tttatgagta tgcgaatata cgtaaatagt acttatgcct
     6601 cccaagcata gacaggaaag attgcatagt agttttgtcg tgttttattt tgtgtttgtg
     6661 ttgtgacggt actacgacgt gagtcgtggt accgtttttt gttcgcccat actgggcgaa
     6721 caaaactatg tttatagctt tcctttgaaa cagaaaacgt cgctttctcc cattgttttc
     6781 ggtaaagaag ttccgggggc gaacagtccg aacactgaag agccagagcc gctcatggag
     6841 gcgtagatcg ctccttgatg atagagttct cttttaattt ccccaataac gggatgttgc
     6901 gggaatacac ttgcttcaaa atcattgatt aggatatcct tccattctgc aactggacgc
     6961 aggattgcct ctttgaccgg atattccgga cggtggggat gaatatttga aaaagcttcc
     7021 cggtagaaac gaaaacgttc ggtttgacaa tcatgatttg gtaaccgctt aatgaaagct
     7081 cgattggtga gaacaggttt ccgattcctt cggcataggt cggcttgttt ttaataaaga
     7141 aagcacagtc cgctcccaaa gtggcggcat atacctccag ctgttcttcg gataattcca
     7201 gctgaaaatg atcgttgagc aactttagca taaaagcggc atcggatgaa ccgcccccca
     7261 gtccggctcc cgagggaata tgcttatata aatgaatttc gacaggggga agatgaaact
     7321 ccttatccag caatgaatag gcctttgcca ccaggttgtc ttccggattg ccggctatct
     7381 ccatgccata ctggtggagg ataatcttct tttctgtttc agaagaagta cggatttcga
     7441 gagcgtcttc gagggctacc ggatagaaaa cggtttccag attgtgatat ccgtccgggc
     7501 gtttttccgt gatggaaagt cccaggttta ttttgatatt aggaaaagcg agcatttgat
     7561 ttatgattta tgaattatga tttatgggtt gctaaattgc gatgttgtgg caaagatact
     7621 aaaatcttca tttttcttta ttcattcttc attattatat tctatctttg tcgttccgat
     7681 tggaaaaagc ctgccaatgg aagccatcca atcataaatc ataaatcaaa attcataaat
     7741 cataaaagtt tttcatggcc gaacagaaaa gaaatacccg caattcaaag tctactaaaa
     7801 tacaaccggt aaatgattat ggacgtattc agccgcaggc gcctgaactg gaagaagcag
     7861 ttttgggagc tttgatgatt gaaaaagacg cttactcatt ggtgagtgag attcttcgtc
     7921 ccgaatcttt ttacgaacgc cggcatcagt tgatttattc tgctatcacc gatcttgcgg
     7981 tgaatcagaa gccggtggat attctgactg taaaggaaca acttagcaaa cgtggagaat
     8041 tggaagaggt gggaggcccg ttctatatta ctcaattgag tagtaaggtg gcttcatcag
     8101 cgcatattga gtatcacgcc cgtattattg cacagaaatc tctggcgcgt gagctgatta
     8161 catttacaag caatatccag agtaaggcgt tcgatgaaac gctggatgtg gacgacttga
     8221 tgcaggaagc ggaaggtaaa ctttttgaga tttcgcagca gaacatgaaa aaggattata
     8281 cgcagatcaa tccggtgatt gacgaagcct ataagctgat tcagaaggct gcggcgcgaa
     8341 ccgacggttt gagtggtctt gagagtggtt ttacaaagct cgataagatg acttccggtt
     8401 ggcagaattc cgaccttatc attatcgctg cacgtcctgc gatgggtaag accgcctttg
     8461 ttctttctat ggctaagaat attgctgtcg attatcggaa cctggtggcg ttgttctctc
     8521 ttgaaatgag taacgttcag ttggtgaacc gtttgatttc caatgtctgc gaaattgaaa
     8581 gtggaaagat caagagcgga cagttggctg gttatgagtg gcaacagttg gactataaac
     8641 tgaagaatct gatggatgca ccgctttacg tggatgatac tccgtctctg tctgtatttg
     8701 aacttcgaac gaaagcgcgt cgtctggtac gtgaacatgg ggtgagaatc attattattg
     8761 actacctcca gttgatgaat gcgagcggta tggcgtttgg tagccgtcag gaagaggtta
     8821 gtaccatttc ccgttcgttg aaaggactgg cgaaagagtt gaatattccg attatcgcac
     8881 tgtcgcagtt gaatcgtggt gtggaaagtc gtgaaggtat tgatggtaaa cgtccgcagt
     8941 tgagtgacct tcgtgaatcg ggagccatcg agcaggatgc cgatatggtg tgctttatcc
     9001 accgtccgga atactataag atttatcagg atgatcgtgg taatgacctg cgtggtatgg
     9061 cggagattgt catcgccaag catcgtaatg gtgcggtagg cgaggtgctg ctccggttta
     9121 agggagaatt tacccgtttc tccaatccgg aggacgatat ggttatcccg atgccgggtg
     9181 agcctgccag ggctatgtta ggatcgaaga tgaatacagg tgatgccggc tcgatgcctc
     9241 ctcctcccgc gcctgatttt gcaccgcaga cagcgaatcc gttcggagca ccaggggatg
     9301 gacctttgcc gttctagttg cgtcctctgt ggtgaaataa cgcgcaattt tttatcaaac
     9361 cttctcggtc aaccgaaaaa tcttattaac tttgcgaatc tttttgagaa acaataaaaa
     9421 attaagtata tgaatatctc ttataactgg ctgaaagagt atgtcaactt cgacctgacg
     9481 cccgatgaaa cggctgctgc gttgacttct atcggcttgg aaacaggtgg tgtagaagaa
     9541 gtgcaaacca ttaaaggtgg tttggaagga cttgtgatcg gtgaagtgct gacctgcacg
     9601 gaacatccta attctgacca tttgcatatt actactgtta atctgggaga cggtgaaccg
     9661 gtacagattg tttgtggtgc cccgaatgtg gctgccggac agaaggtggt ggtagctact
     9721 ttaggtacga aactttatga cggtgacgaa tgttttacca tcaagaaatc aaaaatccgt
     9781 ggggtagaat ctacaggtat gatttgtgct gaagacgaaa tcgggatcgg tacggatcat
     9841 gcaggtatca tcgtattgcc ggaaactgct gttccgggta cgcttgccaa ggattattat
     9901 aatatcaaga gcgattatgt actggaagtg gatatcacgc ctaaccgtgc ggatgcctgc
     9961 tctcactatg gggtagctcg cgacctgtac gcttatctga ttcagaacgg tcgtcaggca
    10021 actttacaac gcccgtcagt ggatggcttt aaagtggaaa accatgactt gaatatcgaa
    10081 gtgaaggttg aaaacagcga agcttgtccg cattatgccg gtgttatcgt gaaaggtgta
    10141 acggtgaagg agagtccgga atggctgcaa aacaaattgc gcctgatcgg tgtgcgccct
    10201 attaataatg tagtggatat tacgaactat atcgttcatg ctttcggtca gccgttgcat
    10261 tgcttcgatg ccggaaagat taaaggcaat gaagtgattg tgaaaacaat gcccgaaggt
    10321 actccgttcg ttacgttgga tgaagtggag cgtaagttga acgaacgcga cctgatgatt
    10381 tgcaacaagg aagaggccat gtgtattgcc ggcgtattcg gcggactgga ctccggttct
    10441 acggaagcta cgacagacgt attcatcgaa agtgcttatt tccatcctac atgggtgcgt
    10501 aagacggctc gtcgtcatgg tttgaatacg gatgcttctt tccgtttcga acgtggtatc
    10561 gatccgaacg gcgtgattta ttgcctgaaa ctggctgctt tgatggtgaa agaactggct
    10621 ggcggtacga tttcttctga aataaaagat gtattcacta ctcctgcaca ggattttatc
    10681 gttgatcttg cttacgaaaa agtacattct ttggtaggta aagtgatccc ggtagagaca
    10741 atcaagagca ttgtgactag cttggaaatg aagattacca atgaaacggc agaaggactg
    10801 acattggctg ttcctcctta tcgtgtagac gtgcagcgtg attgcgatgt gattgaagat
    10861 attcttcgta tctatggata taataatgtg gaaattccga ctacgctgaa ctccagtctg
    10921 actacaaagg gtgagcacga caagtcgaat aaattgcaga atctgattgc agaacaactg
    10981 gtgggctgtg gattcaatga aattctgaac aactcactga ctcgtgctgc ttattatgat
    11041 gggttggagg cttatccgtc caatcacctg gtgatgttgc tcaatccgtt gagtgctgat
    11101 ttgaacgcta tgcgtcagac tttgctgttc ggcggactgg aaagcattgc tcataacgcc
    11161 aatcgtaaga acgctgattt gaaattcttc gaattcggta actgttatta tttcaatgct
    11221 gacaagaaga acgaagagaa ggtactggct ccttattcgg aagattatca cctgggcttg
    11281 tgggtaaccg gtaagaaggt ttccaattca tgggcgcatg cggatgaaaa tagttcggtg
    11341 tatgaattga aagcgtacgt agaaaatata ttaaagcgtc tgggactgga tttgcacaat
    11401 ctggttgtag gtaatctgac agacgatgtt tttgctgccg cactctctgt caacacaaag
    11461 ggcggaaaac gtcttgcttc tttcggtatt gtaactaaga agctgttgaa agcatttgat
    11521 atcgacaatg aagtatatta cgccgacttg aactggaagg aattgatgaa agccatccgt
    11581 tctgtgaaga tcagctacaa ggaaatttcc aaattccctg ctgtgaaacg cgacttggca
    11641 ttgttgcttg ataagaatat acaatttgcc gaaatcgaaa agattgcata cgaaacagag
    11701 aagaagctgt tgaaagaagt ggaactcttc gatgtatatg aaggtaagaa cctcgaagcg
    11761 ggtaagaagt cgtatgcggt gagcttcctg cttcaggatg aaaaccagac tttgaatgat
    11821 aagatgattg ataagatcat gtcgaaactg gtgaagaacc tggaagataa actgggtgcc
    11881 aaacttagat aaacttaaaa ttgtcattat taaaaatata aaccaatggg aagagcattt
    11941 gaatatagaa aggccgctaa actgaaaaga tggggccaca tggctaaaac ttttacaaga
    12001 ctgggtaaac aaatcgctat cgctgtaaag gcaggcggtc cggaacctga aaacaacccg
    12061 acgctgcgtt cggtgatcgc tacttgtaag cgtgaaaaca tgccgaagga taacattgaa
    12121 cgtgctatca aaaacgcaat gggtaaagac cagagcgact acaagagcat gacttatgaa
    12181 ggatacggcc ctcacggtat tgctgtgttt gtagacacat tgacagacaa cacaactcgt
    12241 acggtggctg acgttcgttc ggtattcaat aagttcggtg gcaatctggg tacaatgggt
    12301 tctcttgcgt tccttttcga ccacaaatgt gtgttcactt tcaagaagaa agacggattg
    12361 gatatggaag aactgattct cgatctgatc gactatgacg tggaagatga atatgaagaa
    12421 gatgatgaag agggaacaat tactatctat ggtaatccta agagctacgc cgctattcag
    12481 aagcatttgg aagaatgtgg ctttgaagat gtcggtggag acttcactta tatcccgaac
    12541 gacctgaaag aggttactcc ggaacaacgc gaaacattgg ataagatgat cgaacgtctg
    12601 gaagaatttg atgacgtgca gactgtctat accaacatgc aaccggaaga aggggaagag
    12661 gagtaagaca ggttatggaa tatgtttata agacccaggg ggacttgcag cacgaatatc
    12721 gaactgaatg tggaagatgg agtggtgaag gaagttgctt tctggggagg atgtaatggt
    12781 aaccttcaag gtctttcacg ccttgtgaga gggatgaagg tagcggatgt gattacaaaa
    12841 ctcgaaggag tgcgttgtgg tggcagaccg acttcatgtc ccgatcaatt atgtcgtgca
    12901 ttgcatgaga tgggatattg attgattttt catttatgta aattatatat tgatttgtgg
    12961 cctctggcaa ttggtttgtc ggaggtcatt ttttttagca gaaagtcctt atttcctttt
    13021 ctcgagtagt ccttactcaa cccttttata ataatgtcct cataattagt gtatcatctg
    13081 tgtccatagg tcatctactt attggtcggt attttgaact aaaattgatt ctcactcgtt
    13141 atttataagt atatttgtac tggataaact attatgcaaa aatgaagaat atttttcaag
    13201 acttaagacg caaagatcat aaacgctatc tgggtggact ggatgttttt aaatatattg
    13261 gtccggggct actggttact gtaggattta ttgatccggg aaactgggct tctaatttcg
    13321 ccgccggttc cgaattcggc tattccttgc tttgggtggt taccttgtct accatcatgc
    13381 tgattgtcct tcagcacaat gttgctcact tgggaatcgt taccggactt tgcctttcgg
    13441 aggcggccac taagtacacc cctaaatggg tgtcacgacc tattcttggc acagcagtac
    13501 tggcgtcgat ctctacttcc ctggcggaaa ttctgggagg tgccatcgcg ttggaaatgt
    13561 tattggatat tcctattata tggggagctg tattgactac gctttttgtc tccatcatgc
    13621 ttttcactaa ttcgtataaa aagatagaac gttccatcat tgcgttcgtt tctgttatcg
    13681 ggctttcatt tatttatgag ttgtttctgg tggaaataga ctggccggct gcaacggcgg
    13741 ggtgggtgac tccttctttc ccgaaaggta gtatgctgat tatcatgagt gtgttgggag
    13801 cggtagtgat gcctcataat ctgttccttc attcggaggt gatacagagt cacgagtaca
    13861 ataagaaaga tgatgcttct attaagaagg tattgaaata tgagttgttt gacactcttt
    13921 tctcaatgat tgtaggttgg gcgattaaca gtgccatgat tctgctggcg gccgccactt
    13981 tctttaaaag cggtattcag gtagaggaac tgcaacaggc taagtctttg ctcgaacctt
    14041 tattgggaag taatgcggca attgtatttg cattggcatt gctgatggcg ggcatttcgt
    14101 caactattac gagcggaatg gcggcaggtt ctatttttgc aggtattttc ggcgagtctt
    14161 atcatatcaa ggacagtcac tcgcaggtgg gagttctctt gtctttggga attgccttat
    14221 tgctgatttt ctttattgga gatcctttta aaggattgat tatttcgcag atggtactta
    14281 gtattcaatt gcctttcacc gtgttcttac aggtgggact gacgtcttcc cgaaaggtga
    14341 tgggcgatta tgtcaatagt cgttggagta cgttcgtgtt gtactcgatt gctattatcg
    14401 tttcggtact gaacattatg cttttgtttt cataaaatga acatgaactt ataaatatag
    14461 aatgatgaaa attattactt ataacgtgaa cggactacgt gcagccgtat ctaaagggtt
    14521 accggaatgg ctggcacagg agaatcctga tattctttgt ttgcaagaga cgaaactgca
    14581 accggaccaa tatccgggag aagtgtttga agcattgggt tacaagtctt atttgtactc
    14641 ggcgcagaag aagggataca gtggagtggc catacttacc aagcgggaac cggaccatgt
    14701 ggaatatggg atgggaatgg aagcatacga taatgaagga cgttttatcc gtgcggactt
    14761 cggagacttg tcggtagtca gtgtttacca tccttcggga acaagcgggg atgaacgcca
    14821 ggcctttaaa atggggtggt tggaagactt ccagaaatat gtgatggagt tgcagaagtc
    14881 tcgtcccaat ttgattcttt gcggtgatta taatatctgt cacgagccga ttgatattca
    14941 tgaccctgtc cggaatgcga ccaacagcgg tttccttcct gaagaacggg aatggatgac
    15001 gcgtttcctg tctgcgggat atgtagactc tttccgtacg ctttgtccgg agaaacagga
    15061 atatacctgg tggagctatc gttttaattc gcgtgccaag aataaaggct ggagaattga
    15121 ttattgtatg gtcagcgaac cggtacgccc gctgttgaaa cgggcgtata ttttgaatga
    15181 ggccgtacat tccgaccatt gtccgatggc tctggaa
//
