LOCUS       c00024_gnlPro..        15986 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DFFFCNPM_29.
ACCESSION   c00024_gnlPro..
VERSION     c00024_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 14:51:03
            Original ID  :: gnl|Prokka|DFFFCNPM_29
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15986
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15986
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2773:5986]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2774..5986
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..15986
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15986
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(149..754)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_1"
                     /sec_met_domain="LysR_substrate (E-value: 9e-19, bitscore:
                     58.2, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKHSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEDAVIKDFILLAKKVY"
     CDS             complement(757..918)
                     /locus_tag="ctg24_2"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLSVVVSGINVVISLLIMFNKYQIRKDKKQISDE
                     GHAPLDEN"
     CDS             complement(934..2100)
                     /locus_tag="ctg24_3"
                     /transl_table=11
                     /translation="MKLKKNQDNLKQIASLIEYAFLKDSDLTTDSNFMPRYDHSDGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEILFDLHDQK
                     IPVANLAPFSEKFYRHYGFSNSIYQKEYRFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHTDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGFMAAHIGSIKEFCMTLPEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKVLACMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             complement(2221..2757)
                     /locus_tag="ctg24_4"
                     /transl_table=11
                     /translation="MNIFQEGNPQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGAIKNNRYLIKLFDYGIKQLEEIWQNNGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             complement(2774..3115)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_5"
                     /sec_met_domain="AA_kinase (E-value: 3.3e-19, bitscore:
                     60.0, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDDSLQGVAGVIDKDFSAAKLAEDIQADELVILTTVDNAYVNYN
                     QPDQAPIGKIKIDQLKKYLEAGQFAAGSMKPKIEAVIDFVEKTGKTAIITSLRNASKLD
                     DGVGTIVYN"
     CDS             complement(3284..3706)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_6"
                     /sec_met_domain="AA_kinase (E-value: 4.4e-13, bitscore:
                     39.9, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVAFGGNAIEAGDNSAAAQEKQVKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNLAMPLDTVVSMTQGSIGYWMQKALDDQFKHTNYPH
                     QAVALITQIIVNANDPTFKNPTKLIGPFYTFNEMQR"
     CDS             complement(3901..4509)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_7"
                     /sec_met_domain="OTCace (E-value: 1.9e-37, bitscore: 119.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 1.3e-24, bitscore:
                     77.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDDIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPTQMLADFMTIKEKFGHLKVLTLAYVGDGRDNVADSLLVAGSMLGV
                     NVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIEQGVKGANIIYTDVWVSMGEND
                     WSERIKLLKPYTVTMNMMYMTGTPDDQLIFMHCLPAFHD"
     CDS             complement(4608..4745)
                     /locus_tag="ctg24_8"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSLLKCKDYTPTELNYLIDFALHLKELKKIFRMNI
                     "
     CDS             complement(4757..5029)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_9"
                     /sec_met_domain="Amidinotransf (E-value: 7.6e-31, bitscore:
                     97.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLKNYLHLSEIDLIPTGGGDAIAAPREQWNDGSNTLAIAPGEVVT
                     YDRNYVSNDLLRKHGILVHEIHSSELSRGRGGPRCMSCPLVREDL"
     CDS             complement(5259..5669)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_10"
                     /sec_met_domain="Amidinotransf (E-value: 2.6e-28, bitscore:
                     89.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLIAMPVNEMVKQIIAGIRKNEMQNATPSLADLAENPDYPFYL
                     DPMPNVYFTRDQQATIGNGMTINRMTFRARRRESLFMETVLKHHPDFKNANIPIWCDRY
                     THGRLEGGDELILNNHVFSNRYFSKNFRCRNH"
     CDS             complement(5801..5986)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg24_11"
                     /sec_met_domain="Amidinotransf (E-value: 1.9e-11, bitscore:
                     34.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDYFAHTLEK"
     CDS             complement(6059..6913)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     72.5; E-value: 6.7e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg24_12"
                     /sec_met_domain="LysR_substrate (E-value: 2.1e-28,
                     bitscore: 89.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.5e-23, bitscore: 72.5,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAKEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTVDPKFKDKTGLRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKYSNWITHLQLVRRKDQKVTPLMKRIIDS
                     LSR"
     CDS             7042..9315
                     /locus_tag="ctg24_13"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKEDGLNEAPEPEYNFFKEFLSKLWNLSA
                     WVLEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSNLSDLPDKDVLALVGSATDKRNAGII
                     DIAIDEYLKENDIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWSLAK
                     LARTAELTMLLTFGYLFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFFSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             complement(9384..9881)
                     /locus_tag="ctg24_14"
                     /transl_table=11
                     /translation="MRKQIISAAGIMLAVIGLGAATTQSVDAVVTNPVRQGKRLNLTRN
                     ATVYNRHGVKVGHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKTTVKVVN
                     RIKKHSFVYDENGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTTVT
                     NY"
     CDS             10143..10709
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_15"
                     /sec_met_domain="PLDc_2 (E-value: 2e-09, bitscore: 28.1,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVLTVLPGIGFILYLFFGRQLSHDEIFAIQEEQKKVQRHYLAEQ
                     RDMLKEHDLLPEKERLPRVRMLSELNLNNDDVILTFDNQVKVFISGPELFDQMITDIKN
                     AKKSVSLELYTFYSNQLGHRVLKALEEAAANGAKVRVIYDTSGSRGTKPSFFDHLRAAK
                     LSHLFPLQKSTGLLPHDSITTYIEN"
     CDS             10856..11503
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_16"
                     /sec_met_domain="PLDc_2 (E-value: 6.9e-28, bitscore: 87.8,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDWNTSIRRTNLPKFELKELKPFTVNRKDINDNKNVAMQLFPQDL
                     IINITASDEAEGIIAGAKKYIYIQTPYLIPEESILEALIIAANSGIDVRIMVPCMPDHP
                     FVYRATEYYAKYLVAHGVKVYKYNDGFIHAKTMVSGSNISSVGSANQDFRSYTLNFEVN
                     SFNYNPALTQELKKIFEKDLDKCTLLTNDYFAQQSSWLKFKQYFSRLLSPIF"
     CDS             11631..12425
                     /locus_tag="ctg24_17"
                     /transl_table=11
                     /translation="LANRVKIGVLNLMHDKLDTQQRFARVLPDADLTFFYPRMHYQNRP
                     VPPEVAKTSQPLDLNQIKEFDGFIITGAPLDHLDFDQVTYIEEVRCLLQLLDKYKLQQL
                     YFCWGAMAALDYFYNIQKRILSKKIFGVFPHLIIEPHPLLNGLSKGFIAPHARYAEMDK
                     TQIMQDPRLTINSVDDNGHLFMVSSLEKPEQNFIFSHIEYGRKGLKKEYEREIAAHPER
                     HYKKPENYSLSNLLFQWKDTQKTFFNNWLTQVKKSKLVLLDK"
     CDS             12441..13370
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg24_18"
                     /sec_met_domain="PALP (E-value: 5.9e-69, bitscore: 223.2,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSIIYNSVTELIGNTPLLKLNRVVPDDAADVYVKLEFENPAGSIK
                     DRIALAMIEKAEREGNLKPGGTIVEPTSGNTGIGLAMVAAAKDYHIIIVMPETMSVERR
                     KLMKGYGAELILTPGADGMKGSIAKAEELVKEKGYFMPMQFENTENPNIHELTTGPEII
                     AAMNGIGKSVDAFVAGVGTGGTLSGIGHALRRENPSTKIFALEPTESPLLKDGKTGKHG
                     IQGIAAGFIPKNLDKDIYDDIITVSTDEAMATAREVAKNEGFLPGISAGANIHGAIEIA
                     KKLGKGHAVVTVVPDGGDRYLSTALFNA"
     CDS             complement(13514..14041)
                     /locus_tag="ctg24_19"
                     /transl_table=11
                     /translation="MAIDFSKYIASVKDFPNKGIVFRDITPILQDGELYRIATHELAEY
                     AKSRKADVIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEYGSNSLE
                     MHKDAIKPGQRVVLCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLKGREKLPD
                     VDIYSLVQYHGA"
ORIGIN
        1 ccattttgac ctcgtttcta aatgttgtgt ggtaactaca ttctatcaaa caggtccgaa
       61 tggacttttt attttttatc aagtgttcaa cttaatttta caatcagcgc atttttattt
      121 ttacagtatt ttgctgttcc aagatagatt aatatacttt tttagctaac aaaataaaat
      181 ctttaattac tgcatcttca ttggtataaa aagctgcaat cttttgccac atttgttgtc
      241 cattagacaa taaaaacaat cgttgtaaag tatcattact aattaaactg gcggttgctt
      301 cattcattaa aaaatatcct gatccagaag ctactaacaa tgctgcctct tctacggaat
      361 ttgaagcaat gaatgggctt ctaatctgat aaatatcttt aaataaatgg agttctgcag
      421 cctcttcttc aggcttagct acaataaaac aggttaaatc agctagatca tctttattga
      481 tcatctgaac accgctagga taactaccct tttgcaaaat agccattact gcttcctgac
      541 ctaagatttc tttcttaaaa tcgagctgat catcgcgcaa atcactaatc gctaaatcaa
      601 cttcattttt ggctaattta tcaaaagctt catcgtgtcc cattccaatt aattcaattt
      661 ctacatcaga atgtttttgc ttaaattggt ctacaattcg atctaattgt cttctaccaa
      721 gttggttaaa gtatgctatt ctcaattttt tcatagttaa ttttcatcca atggggcatg
      781 accttcatct gatatttgtt ttttatcttt tctaatttga tatttgttga acataatcaa
      841 tagcgaaata accacattta ttccactaac taccacgctt aaaaatttta gtaatctaac
      901 tttcttttgc ttactcattt tggatacctt cttctaaaaa taatcataaa atgagacttt
      961 accttttaca aagtccaact ttttaattcg ataatctgtg atcaaaccaa gtttaattgc
     1021 ggattccata gttaaacgtc ctaataagat ttgagtccat gttgtaattg gaccagagaa
     1081 atcaactagt tcatcttctt ttcgttcaca cttaacttgg tgatcataat tagttaattg
     1141 ccaaacgcca atattccatg gacactgatc atcataatta acttcgatgt taaaagtacc
     1201 ctcttgcaat gggcgcatgc atgccaagac tttttggaaa tcaataattc tactcatcat
     1261 atatggatga agttgaatat ccaattcatt ttgctctgga aaaagttcag ccaataaaga
     1321 cttctcaggc aatgtcatac aaaactcttt aattgaccct atatgagctg ccataaagcc
     1381 taatatgctt aataatcctt gaggcgtaat tgaatataat tcatcagcca taaaacagtt
     1441 atcaattatg cgataaatca agtagctcat cggccgacca gcttcatcga agtaaacagc
     1501 aatctctcga tgatgataat aatcatctaa tctattccac caccaagctt ctctgatgat
     1561 cgtatttctt tcatcgtcag tatgcaactg acgttcatat aattgaatca caccattttg
     1621 aacaatcaaa tcattccatt ttccacgaat tatcttacct ttgcgtggta atctgaaaga
     1681 agcaagtgca gcccccgaaa agcgatattc tttttggtaa atactattgc taaaaccata
     1741 atgacgataa aatttttctg aaaatggagc tagatttgca actgggattt tttgatcatg
     1801 caaatcaaaa agaatttctt tcattaattt agatatatgt ccacgtcctc tgtattcagg
     1861 atatgatgcc acataaccaa tacctgccag tggaacatga tgaccaaata tctcagcttt
     1921 aaacttattg accatcatat aactggtcaa tttttcttga tcaaaatatc catatccatc
     1981 actatgatca tatcggggca taaagttact atctgtagtc aaatcagaat cttttaaaaa
     2041 agcatattca atcaatgaag caatttgttt taaattgtct tggtttttct ttaatttcat
     2101 agttttcctt acaatatata ttcataactt tacttatatt ttagaacatt ttatgtattt
     2161 ttcgttagct ttttttaaga tttaaatgaa aaaacgggat gattagcctc ccatcccgtt
     2221 ttaattattt acatacttcg catataaact agaaatgtat ctttgcatct cttctactga
     2281 gtgtcgccgt gatcgagcac actctttagc agggcgattg cataaatagc agcggcgact
     2341 agagtattca agctcttggc gtgaaagtgc agttttccct ttaattaata catcggcatc
     2401 aaataatcgt cctattttat tattttcttc aaataaaatt gtagataatt taactacttt
     2461 gctagattct cgcaaaacat agaaattttc acatccagca tcattattta atgcttttac
     2521 taatttatag tcatatccat tattctgcca tatttcttct aattgtttaa ttccgtaatc
     2581 aaataatttg attaaatatc gattattttt aattgccccc gggatattta agtttatatc
     2641 aaccaaagtc gcatcaggat actttttaaa aatagcttgc tgcaaagcta cacgataatc
     2701 ttttccagct aatacctgag caatattttg cggatttcct tcttgaaaaa tgttcattta
     2761 tatctcaccg cagttaatta taaacaattg tacctactcc atcatcaagt ttacttgcat
     2821 ttcttaaaga agtaataatt gcagtctttc ctgttttctc tacgaaatca atgacagctt
     2881 caatttttgg cttcatgctg cctgcagcaa attggccagc ttctagatac ttctttaatt
     2941 gatcaatctt tatttttcca ataggagctt gatcaggttg attatagttc acgtaggcat
     3001 tgtcaacagt agttagaata actaattcat ctgcttgaat atcttcagct agttttgcgg
     3061 cactgaagtc tttatcaatt actcctgcta cgccttgcaa actatcgtct ttcactacaa
     3121 caggaattcc atcacctccg gcagcaatag gaacaaactt gctctttagt aaagtgtcaa
     3181 tgcctggtgc attaataatt ttaacgggct ttggagaaga aactacttga cgatagcctc
     3241 gacctgtatc ttgcttataa gtatattcag gatgatagat tttttacctc tgcatttcgt
     3301 taaatgtata aaatgggcca attagtttag ttggattctt aaaagttgga tcattcgcat
     3361 taactattat ctgagtaatt aaagcaacag cttgatgtgg ataatttgta tgtttaaatt
     3421 gatcgtctaa ggccttttgc atccaatagc cgatactgcc ttgagtcatt gatactactg
     3481 tatcaagcgg catagcgaga ttatctttac ttgaaccttt gtattgttgc aaaagcaaat
     3541 taccaacctg cgggccatta ccatgaacaa tcgctacctg atcaccattt tcaatcattt
     3601 tagcaacaac cttcattgtc tttttaacct gcttttcttg ggcagctgca ctattatcac
     3661 ctgcttcaat agcattgcca ccgaaagcta caactattct tttcatcttt atttacttcc
     3721 ttcatcaact gacggaataa acaaattgcc caaagtagcg gccattattg ctttgataga
     3781 atgcaatcta ttttccgctt cagtaaattg ccaagcgtat tgagagttaa agacttcatc
     3841 tgtaacttcc acttcactta gaccatattt ttcataaatt tctttgccaa ctttagcagt
     3901 tcaatcatga aacgcaggca aacagtgcat aaagattagt tgatcatccg gggtgcctgt
     3961 catatacatc atattcattg taaccgtgta aggctttaac aatttgattc tctcactcca
     4021 gtcattttca cccattgata cccagacatc agtataaata atatttgcac ctttaacgcc
     4081 ttgttcaatg tcatcagtaa tcaaatttct tgatccagaa tctttggcaa aaccttctgc
     4141 aattttttgt acatcagggt gagtgaataa aggctttggc gtaactatgt gtacattaac
     4201 tccaagcatg ctgccagcca ctaaaagact gtcggcaaca ttatcacgtc catcgcctac
     4261 ataagctaaa gtaagtacct ttaaatgtcc aaacttttct ttaatagtca taaagtcagc
     4321 caacatttgg gtcggatgcc atttatctgt taaaccattc caaacaggga caccagaata
     4381 tttagccaaa tcttctacat ctttttgagc aaaaccgcga tattcaatgt catcaaacat
     4441 actgcccaaa accttggcag tatcttcaat actttccttt ttacctaaat gaatttcacc
     4501 agcacccata tattcaggat ttgcgcctaa atcattgcat gcaactacaa aggctgaacg
     4561 tgttcttgtt gaagattttt caaataaaag agctatattc tttcctttta aatattcatg
     4621 cggaatattt tctttagttc cttcaaatga agtgcaaaat caattagata gttaagctcc
     4681 gttggagtat agtctttgca ttttaataaa cttctgcctt gaaacacatt ttgtaaatat
     4741 ttcattttga cgcctcttac aaatcttcac gaacaagtgg acatgacata catcttggac
     4801 ctccacggcc acgagaaagc tcacttgaat gaatttcatg aactaaaatg ccatgctttc
     4861 ttaacaaatc atttgataca taattacgat catatgtaac gacttcacct ggcgcaatag
     4921 ccaaagtatt cgagccatca ttccactgct ctcttggggc tgcaattgca tccccacctc
     4981 cggttggaat taggtcaatc tccgataagt gcaaataatt ctttaacact ttgatcaaat
     5041 cagtttctgg ggtaatttta atctcaccat gatcatcttg ctctaaaaca taaatatcaa
     5101 tctttcctga tttgtctaaa ataaaaggat gaacagtaca ctaatcataa ttaatcattg
     5161 taaagactgt atccagatgc atcatggcat gattatgtgg tattttaatt gctaaaattg
     5221 tgtcataact agaatgacca aacaggctat gagcaaggtc agtgattgcg gcagcggaag
     5281 ttctttgaga aataccgatt gctaaaaaca tgattgttta aaatcagctc atcgccacct
     5341 tctaaacgtc catgagtgta acgatcacac caaataggaa tattggcatt tttaaagtcg
     5401 ggatgatgct ttaaaacggt ttccataaat aatgactcac gtcttctagc tctaaacgtc
     5461 attctattaa tagtcatgcc attaccaata gttgcttgtt gatcacgagt aaaatacaca
     5521 tttggcattg gatccaaata aaatggataa tctggatttt cagctagatc ggctaatgaa
     5581 ggagttgcat tttgcatttc attttttcta ataccagcaa ttatttgctt aaccatttca
     5641 tttactggca ttgctattaa atagtccatc agtaattgat gtaatggatc ttctttttta
     5701 tattggattc ttctaataat tgatctacaa attttgtacg gacatcttca ttagtcaaag
     5761 agtgagctaa taaatcttct aaataaacga catgaactcc ctatttttcc aaagtgtggg
     5821 caaaatagtc atgctctttt tgagctattt ttaaatatgg aatatcgtca attaacattc
     5881 gatttaagat atccggtgaa agattttcta attctcttcc cggtcgatgc agcataactg
     5941 tttctaattt gccaatttcg gaataaacat gaattaagtc agtcattata gcgcctccta
     6001 attcaaatta tgtatccgct tacaataatt aaggatcaat taggtagaag ttacaatctt
     6061 aacggcttag tgaatctatt attcttttca ttaaaggcgt caccttttga tccttgcgcc
     6121 tcactaattg caaatgcgta atccaattac tatatttaat aggaataaga tcatcaggtg
     6181 catacgtaga agcaatagat tcaggaacaa gagcaatccc catttttctc ttcgcccaag
     6241 taatcgctgt tctagaatca tcacatttaa cagcataaaa cggcttaatc ccatgatgag
     6301 caaaagtctg gttaaaaatt tcttcaaatc ttcgataaat aatgaggggc tgctcattta
     6361 gatctttaat ccttaatccc gtcttatcct taaatttggg atcaacagta actgccatca
     6421 ttctttcagt agttaaagtt tttgcattta agccattacg attataaggc gtacgcacaa
     6481 ttcctaaatc gattgtcttc ttttccaatt tatcgataat gccaaaggta ttatcttcat
     6541 aaatatcaaa gttgatttcc ggataaaact tagttaaatc ttgaaaactt ttcataggaa
     6601 ttagtccagt tgatgatgaa gccatgccta ttgcaatcgt gcctagttca cctgaaacag
     6661 ttttatgaac ctgatttttc acgctttctg ataaagagag aatttcacta gcatagctct
     6721 gcaaaatttg tccagcatct gttaattcaa ttccatgagc agtacgctta aataattgtg
     6781 ctcctagttc tatttctagt tgctttaatt gataactcag cggcggttgt gcaatgtata
     6841 gtcttttagc tgctgaagtg atttgctttt ctttggctac tactaaaaag tagcgtaatt
     6901 gtttaatatt cattaataat ctatcttttt tattttagtt gtatctctta ttaaaaattt
     6961 ctatatctta tattttaatt tagtattttc attcaaacaa catatgtgct actttattaa
     7021 ggtagatttg gagggaataa aatgtctgaa aaatttcatg gcttaactca agccgaagca
     7081 gataagagac ttaaggaaga tgggttaaac gaagcacctg aacccgaata caactttttt
     7141 aaggaatttc tatcaaaatt atggaatctt tctgcctggg ttctagaagg tgccttaatc
     7201 ctcgaatgta tcttaggcaa atggattcaa tctttgttcg tcttgttgat gcttcttttt
     7261 gcggctttta acggtgcatc caagaagaaa cagtcacggc gggtattaaa taccatttca
     7321 cataagctaa cccctaaggt ggctgtagaa cgcgatggta agtggatcaa aattgactct
     7381 aagcaattag ttagaggcga cttaatctca cttcaacgtg gagatgtact tgcagccgat
     7441 gtaaaaatgg ttagcggtaa gatcgcctgt gatgaaagct caattaccgg tgaatctaag
     7501 cccgttaaaa agaacattga tgacacagct tatgctggta ctactgttgt tgaaggcgat
     7561 ggattagcaa ttgttactgc aactggtaaa gattcaagaa gtggtaagac cattaacttg
     7621 atcaacaatt cagctgcacc tggtcacttg caacaacttt taactaagat tatttactac
     7681 ctttgcctac ttgacggtgt acttacctta gttattatca ttgcttcatt ctttaagggt
     7741 ggtaattttg atacgtttat caacatgttg ccattcttag ccatgatgtt catcgcttca
     7801 attccggttg cgatgccgtc aacctttgca ttgtccaatt catttgaagc aacccgttta
     7861 agtaaagaag gcgtcttaac agctgattta actggtatcc aagatgcagc taacttaaac
     7921 ttgcttttac ttgataagac gggaacaatc actgaaaaca aaactgcagt tgctagttgg
     7981 agcaatttaa gcgatttgcc agataaagat gtacttgctt tagtcggtag tgcaactgat
     8041 aagcgcaatg caggtatcat tgatatcgcc attgatgaat acttaaaaga aaacgatatc
     8101 cctgtcatgg acgttgaaca ctttacccca tttacttctg acactggcta ttctatggct
     8161 gaagtagatg gtcacaatgt taagttaggt tcatttaagc aactttcatt aatcgataag
     8221 aatgcaaatg aagcagttga aggcatcaat tttaaagctg gacgctcagt tgccgtgtta
     8281 attgatgaca aacttgcggg agtatttatc ttacaagata aagtaagaaa ggactctaag
     8341 gctgctttag cagaacttaa aaaacggggc gtacgtccaa tcatgttaac tggtgataat
     8401 caaagaactg ccgcagcagt cgctgaacaa gttgatttaa ctggtaacgt tatctctatt
     8461 catgactttg atgaaagcac cgatattgat gaattagcag gaattgccga tgttttacct
     8521 gaagataaac ttaagatggt taaattcttc caagaaaaag gttatatcgt tggtatgact
     8581 ggtgatggtg ttaacgactc tcctgcttta aagcaagctg aagttggtat tgctgtttct
     8641 aacgctgccg atgttgccaa gcgttcaagt aagatggtgc ttctagatga tggcttaagc
     8701 tctattgtta aaattcttga tgctggtcac cgtgtatatc aacgaatgac tacttggtca
     8761 cttgctaagc tcgccagaac cgccgaatta actatgcttt taaccttcgg ctatctcttc
     8821 ttcaactata ttccaatggc attaaatgct atggttattt acacaatcat gaataacatg
     8881 gttaccatga tgattggtac cgaccgtacc catattactt acaaaccaga aaattggaat
     8941 atggcaaggt tagccaaaat cgcattctct cttgctgcag gttggacagt tatcggtatc
     9001 gcttttttca gctacctcaa catgcatggc tggagtcaca attctatctc taccatggtc
     9061 tatgtttact tagttctaag tgcaatgtta attgtattaa ttactagaac tcgtaaatac
     9121 ttctggcaag attatccatc taaacttgta ggtattgttc aaattgccga tgtcgcatta
     9181 acctttattt tagctttatg cggtttagca atggctcaaa ttagttggca aaacttatta
     9241 attaccgttg tggttgcatt aattgcagca attattattg atttgattta tcaaccagta
     9301 atgaaaaaca gataattaac ttaaaacaaa aacactctga aaactaaatt actacaatgt
     9361 agttttcaga gtgttttttt tgattaataa ttagtaactg tagtcaaggc attcaaagcc
     9421 ttaacatatt caccatcagc aattttgata aatggttttt cattaatttc tttatggcct
     9481 aaatagttaa ccttagcacc acgctttaaa aatttgcctg ggattttttc accattctca
     9541 tcataaacaa aggaatgctt tttgattcta ttaactactt ttacagtagt cttcatatat
     9601 ggcaagaagg cttcttcctt aacaaatcta tttttacgaa tctttacata agtattacca
     9661 ttaattactt ttatggcacg tactttgtaa agctttccct ttcttaaatg tccaacttta
     9721 acaccatgtc tattataaac agtagcattt ctagttagat ttaatctctt accttgtcta
     9781 actggattag taacaactgc atcaacgctt tgtgtagttg ctgcgcctaa tccaataact
     9841 gctaacatta tacctgcagc agaaataatt tgttttctca tcataatcca cccccgtagt
     9901 gtttatacca ttctccatcc cttattttat caaaaattat cgaattggaa gcatttttta
     9961 ctcatctgtt ttataactat ttgcttaatt ctgctaaaat tatttataac actacttaat
    10021 tcatgatttt aacttgggat ataatccgta ggactatcga agtcttatgg attatcaata
    10081 ttgcgtttgc tgtatggacg gtctttagaa gtcgccgcag cgttgttgca acttgggcat
    10141 agatgcttgt attaaccgtt ctgcccggta tcggttttat cctatatctt ttctttggtc
    10201 gtcagctttc acatgatgaa atctttgcta ttcaagaaga gcaaaaaaag gtacaaagac
    10261 attatttagc tgagcaacgc gacatgctta aagagcacga tcttctacct gaaaaagagc
    10321 gtcttccacg agtaagaatg ctttcggaac taaatcttaa caacgatgat gtgattttaa
    10381 cttttgataa tcaggtcaaa gtatttattt ctggaccaga actttttgac caaatgatta
    10441 ctgatatcaa aaatgccaaa aaatctgtca gcttagaatt atatactttt tattctaacc
    10501 aattagggca tcgtgtttta aaagccttgg aagaggctgc agctaatggt gctaaggtaa
    10561 gagtaattta tgatacctct ggatcaagag gcactaagcc aagctttttt gaccatttaa
    10621 gggcggcgaa gctcagccat ttatttccac ttcaaaaaag cactggttta ctaccccacg
    10681 actcaattac cacttacata gaaaattagt tattattgac caccatattg gctatattgg
    10741 cggatttaat attggagatc aatatgtcaa taaatcacca aaattcggtc attggcggga
    10801 tacccattta cgtgtaattg ggcaatcacc aattctaatg gaggtccggt ttgcaatgga
    10861 ctggaacacg tcaatcagaa gaacaaattt acctaaattt gaattaaagg aacttaaacc
    10921 atttactgtc aatcgaaaag atatcaatga taataaaaat gtcgctatgc aattgtttcc
    10981 tcaggacctg ataatcaaca ttacggcatc agacgaggct gagggaatta ttgcaggagc
    11041 taaaaaatac atttatattc aaacgcctta tttaattccc gaagaatcaa ttcttgaagc
    11101 cttaattatc gctgctaaca gcggtattga tgttcgaatt atggttcctt gcatgcccga
    11161 tcatccattt gtttatcgtg ctacagaata ctatgctaag tatttagtag cccatggcgt
    11221 taaagtatac aaatataatg atggttttat tcatgcaaaa actatggtta gcggttctaa
    11281 tatttcttca gttggttccg ccaatcaaga tttccgaagc tatacattaa actttgaggt
    11341 aaactcattc aactacaacc ctgctttaac tcaagaatta aagaaaattt ttgagaagga
    11401 cttagataaa tgtacccttt taactaatga ctactttgct caacaatcat catggttaaa
    11461 atttaagcaa tacttctcaa gattattatc acctattttt taatgaaaag ccctctatcg
    11521 gtttatccga tagggatttt actttgtatt ttaaaaatgc agttttattt ctttacttat
    11581 tttttatagg ttatataatg ataactatta aaaagtaagg aggataaaac ttggctaata
    11641 gagtaaaaat aggcgttttg aatttaatgc acgataagtt agatactcaa caaagatttg
    11701 cacgcgtttt gccagatgca gacctgactt tcttttatcc acgtatgcat tatcaaaatc
    11761 gtcctgtccc acctgaagtt gcaaaaactt cccagccatt agatcttaat caaatcaaag
    11821 agtttgatgg ctttatcatt acgggcgcac ctttagatca tcttgatttt gatcaagtta
    11881 cctacatcga ggaagtccga tgtttgctcc aactattaga taaatacaag ttgcagcaat
    11941 tatatttttg ctggggtgca atggccgctt tagattattt ttacaatatt caaaaaagaa
    12001 ttttatcgaa aaaaatcttt ggtgtttttc ctcatttaat tatcgaacca catcctttat
    12061 taaatggact cagcaaagga tttatcgctc cacatgctcg ttacgctgaa atggataaaa
    12121 cacagattat gcaagatcca cgattaacca ttaattcagt tgacgataat gggcatctat
    12181 ttatggtctc ttctttagaa aagcctgagc aaaattttat tttctctcat atcgaatatg
    12241 gccgaaaagg ccttaaaaaa gaatatgaaa gagagattgc tgcacatcca gagcgacatt
    12301 ataagaagcc agaaaattat tcattatcaa atctattgtt tcaatggaaa gatactcaga
    12361 aaacattttt caataactgg ctaactcaag ttaaaaaaag caaattagta ttattagata
    12421 aataaaacga ggtatacatt atgtctataa tttataattc agttacagaa cttatcggca
    12481 acactccatt acttaagttg aatcgcgttg tacctgacga cgcggcagat gtctatgtaa
    12541 agttagaatt tgaaaaccca gctggttcaa ttaaagacag aattgcttta gctatgatcg
    12601 aaaaagctga acgtgaaggc aacctaaagc caggtggcac aattgtagaa cctacttcag
    12661 gcaataccgg tatcggttta gccatggttg ctgcagctaa ggactatcac attattattg
    12721 ttatgccaga aactatgagc gttgagcggc gtaaattaat gaagggctat ggtgctgaac
    12781 ttattttgac accaggtgca gacggtatga agggttcaat tgctaaggcc gaagaattag
    12841 ttaaagagaa aggctacttc atgccaatgc aatttgaaaa tacagaaaat cctaatattc
    12901 atgaattaac tactggtcca gaaattattg ccgcaatgaa tggtatcggc aaatccgttg
    12961 atgcctttgt tgctggtgtt ggtactggtg gtactttatc aggaattgga catgcactta
    13021 ggcgtgaaaa tccatccact aagatatttg cacttgagcc aactgaatct ccactcttaa
    13081 aagatggaaa aacaggtaaa catggtatcc aaggtattgc cgcaggtttc atccctaaga
    13141 atttagataa ggatatctac gatgatataa ttacagtttc tactgatgaa gcaatggcta
    13201 cagctcgtga agtagctaaa aacgaaggct tcttacctgg tatttcagct ggtgcaaaca
    13261 tccatggtgc aatcgaaatt gctaaaaagt taggcaaggg acatgctgtg gttactgtag
    13321 ttccagacgg cggtgatcgt tacctttcaa ctgcattatt taatgcttaa aacttaattt
    13381 ctgtaaacaa atactcctaa gtaaaatttc cttaggagta ttatttttat ttctgttgat
    13441 tgtgcaccag tcaatgttgg tacaacactt ttagtataat gacctttact aattagatca
    13501 atattgaatt tatttaagca ccatgatatt gcactaagct gtaaatatca acatcaggca
    13561 acttttctct accctttaaa tcaggcaatt caatgtaaaa tgcagcacct acaagcttac
    13621 caccaagatt ttcaattaat tccttagaag ctcttaaagt acctgcagta gccattaaat
    13681 cgtcacagag aacaactctt tggccaggct taattgcatc tttatgcatt tcaaggctat
    13741 ttgaaccgta ttccaagtca tatgaagcac gttcaacttc tcttggcaac ttatgtggct
    13801 ttcttgctgg aacaaaacct aagcctaact cagttgcaac aggacagcct acaataaagc
    13861 cacgtgcttc aggacctacg attacatctg cctttctact ctttgcatat tctgccaatt
    13921 catgagtagc aatacgatac aattcaccat cttgcaaaat aggtgtaata tcgcgaaaga
    13981 caattccctt attaggaaag tccttaacac ttgcaatata tttactaaaa tcaatcgcca
    14041 taagaagaaa aacctccata attctgtgcg tttgtattca aacactttta acttgtatat
    14101 tttaccaaag atttgttata aaagtactga aatcttgata tttatctatc tttttaccaa
    14161 attattaaca tatgtaatta atttttgagt aggcatcgtt cttagttgat taataaattt
    14221 aatttgtgaa ctcgttgcca ttaaatattt agaagctgtc aatggttgct tctttggatt
    14281 agactcacca actaattttt gatcgtctaa tttaacaaaa cctaattcaa agaatactcg
    14341 caaaataaac aatacactat cataatccaa acctagatat ggtgctacag tgcgatagtc
    14401 ttcaggcttt aatgctggat gggcataaat atactttaac acttttccga aataactctt
    14461 tgctggaatt tgttcaacag gtaactgatc taataaaaag cataaataaa tttgttgata
    14521 atcttttttt aaagctgcat ttaattccac ttgattgcga ggcacatcaa gcaaagctac
    14581 tgtttcaccc gattgatcat aatctttaac caagctaatt ttatcatcat caatttgaag
    14641 gctattctta acaattggaa tattcttttt gtcaaaaagc aaataacgat ctgcaaggcc
    14701 catgacaaat ttctcttgtc ttaaatcaat tactgatgtt ggcacagcta attttgggga
    14761 tgcaaaggct attccttcca tgatgccttg caaagatact tgtttgcgat aagtattcaa
    14821 agagagagta acaaagattt ttgaaataaa tggtaacaaa ttattattca aataatcctt
    14881 attaaatccc acaattgcta aattgccgtc ttttttatta gctattaatt taacatgatt
    14941 cttatctttt cctattttga aaaagtgtgt aatagttgga tccgaaatac taaaaattgg
    15001 ctgcggatca ccagtaccaa atggtcccac ttgattaatt tgagccaaag tttgaggtga
    15061 taagtcatgc ataggcaatt ccatatcgta ctctttagtc tctaaaccac cgtcaacatg
    15121 aaaatcggct tcaaactttt tccgtaggtc atttactttg tcttcttcca tggataaacc
    15181 acaagcaaaa tcatgacctc caaatttggt caatagactt tcttttaacg gattaagagc
    15241 atcaaataag ttaaaaccac tgaatgaacg acctgatccc ttaatctccc cttcatcgtt
    15301 tttagttaaa acaattgttg gtttatgcag tttttccact atcttgttag caacaagccc
    15361 caaaactcct tcatgaaaat caggatcata taaaactaaa gtattttgct tttgccaact
    15421 attttcacga actaattcca tgcagcgatc gtaaacctca gtagttagct ctttacgctt
    15481 attatttaag tcttcaatct gatctgcgat cttctgtgcc tcaagatcat catcactaag
    15541 caaaagctct actgccagat tagcattagc caaacgtcca acagcattaa gtctaggagc
    15601 aatattaaag cctacatctg tctcattaat cgtttctagc gttaaaccgg catttttgat
    15661 aagcgctctt aagcccggtc gttcggtttg attaagaaca tctaacccac gttttacaat
    15721 aatatggcct tcaccagtaa ctttaaccat gtcaccaata gtaccgatca ttgctaaatc
    15781 tagcaattct ggtacaggat cctgcataag ctcacgacaa attgtataag ctacacctgc
    15841 accacaataa tcatcaaaag gatattcttg accaggataa ttacagtgaa caattgcata
    15901 agcatctggc ttattttctt gaaaagtatg gtgatccgta ataatagtat caacgccatg
    15961 ttctttagcg tattcaactt cttcaa
//
