LOCUS       gnlProkkaBGDFKAMC_52   17550 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|BGDFKAMC_52.
ACCESSION   gnlProkkaBGDFKAMC_52
VERSION     gnlProkkaBGDFKAMC_52
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:13:27
            Original ID  :: gnl|Prokka|BGDFKAMC_52
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 23819
            Orig. end    :: 41369
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17550
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:11513]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..11513
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..17550
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="neighbouring"
                     /product="RaS-RiPP"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /protoclusters="2"
                     /tool="antismash"
     region          1..17550
                     /candidate_cluster_numbers="1"
                     /candidate_cluster_numbers="2"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /product="lanthipeptide-class-iv"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             complement(1835..2140)
                     /locus_tag="ctg37_35"
                     /transl_table=11
                     /translation="MSHNHDYNHDHEVITLVDEQGNETLFEILLTIDGREEFGKNYVLL
                     VPAGAEEDADGEIEIQAYSFTENEDGTEGDLQPIPEDSDAEWDMIEEVFNSFIDEN"
     CDS             complement(2249..2668)
                     /locus_tag="ctg37_36"
                     /transl_table=11
                     /translation="MRVMGLDVGSKTVGVAISDPLGFTAQGVEIIKINEEAKEFGFDRL
                     GELVKEYQVDKFVVGLPKNMNNTEGPRVEASKAYGDKIKEIFNLPVDYQDERLTTVQAE
                     RMLVEQADVSRGKRKKVIDKLAAQLILQNYLDRMF"
     CDS             complement(2668..2934)
                     /locus_tag="ctg37_37"
                     /transl_table=11
                     /translation="MGFTDETVRFNLNDGDKDEISNTLTNVYRSLAEKGYNPINQIVGY
                     VLSGDPAYVPRYNDARNQIRKYERDEIVEELVRYYLKGNGTDL"
     CDS             complement(3061..3249)
                     /locus_tag="ctg37_38"
                     /transl_table=11
                     /translation="MAKVCYFTGRKTVSGNNRSHAMNKTKRVVKPNLQKVTVLIDGKPK
                     KVWASARALKSGKVERV"
     CDS             3419..4687
                     /locus_tag="ctg37_39"
                     /transl_table=11
                     /translation="MPDNLALRMRPRSISEVIGQKHLVGEGKIIRRMVEANMLSSMILY
                     GPPGIGKTSIASAIAGTTKFAFRTFNATVDSKKRLQEIAEEAKFSGGLVLLLDEIHRLD
                     KAKQDFLLPLLENGNIIMIGATTENPFFSVTPAIRSRVQIFELEPLSNEDIKEAILNVL
                     GDKERGFAFEVHLDDDALDFIATATNGDLRSAYNSLDLAVMSTPASGNGQHHITLDIVE
                     NSLQRSYITMDKDGDGHYDVLSALQKSIRGSDVNASLHYAARLVEAGDLPSLARRLTVI
                     AYEDIGLANPDAQVHTVTALEAAQKIGFPEARILIANVVIDLALSPKSNSAYKAMDAAL
                     ADLRKSGNLPIPRHLRDGHYAGSKALGNAQDYKYPHAYPEKWVKQQYLPDKLRGVNYFQ
                     PNETGKYERALGANKERIDKLSR"
     protocluster    4003..17550
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[14002:16162]"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="2"
                     /tool="antismash"
     proto_core      14003..16162
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="2"
     cand_cluster    4003..17550
                     /candidate_cluster_number="2"
                     /contig_edge="True"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="2"
                     /tool="antismash"
     CDS             complement(5129..6268)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 86.6; E-value: 4.4e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg37_40"
                     /transl_table=11
                     /translation="MASVRYRKRGDSNLWTYEIRNEGKTVAHNSGFKTKKLAESEAEPI
                     LQELRLGKRISRDISLADLYQEWLELKILPSSRSEETKKKYLLRKNTIERLFGNKKVTQ
                     IRASEYQRIMNKYGQTVGRNFLGRLNTGIHQSIQMAIADKVLIDDFTQHVELFSSKEQQ
                     MTEEKYLHTEKDYLDLLLAVKRKFNYQRSIVPYIVYFLLKTGMRFGELVALTWNEVDFD
                     RGLLKTYRRYNTLSHKFVPPKNKTSIRMVPIDEECIKILRLLQTEQERANMELGIKNRY
                     RMIFQHFGYIHSVPDIASVNKALSVLLNELDIYPIITTKGARHTYGSYLWHKGFDLGVI
                     AKILGHRDISMLVEVYGHTLEEKIFEEFNQIRDIWKDCS"
     CDS             complement(6270..6458)
                     /locus_tag="ctg37_41"
                     /transl_table=11
                     /translation="MDNNLISNKELIEMGYRPHTANDIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVNEILGTEVA"
     CDS             complement(6470..7444)
                     /locus_tag="ctg37_42"
                     /transl_table=11
                     /translation="MVSIQDLRSIQERCEIGELVQRLDVSIDRLTVIWDTDTGSLRRIF
                     KNLKQAISTRVDSFEIHDNVRDDVFTLAKDFNKYDSINIIFFQLSTYGGEQLIRIDFNP
                     NTLKEFDGMKVWRQLMYFARLNSLTVRLSRFDLAFDIFNRPEIVNLQHIKGGVPHKVFY
                     GRGGELETKYWGSSGSNVQVRLYDKNKEIIAHKREEKLDLGVNPFWWRLEFQLRTKAIG
                     EDMVQDIMNRLDNFGFYKLEHIRVDQRAFTIIFLSNPELLSLAFPNLKSDSIKKKKTRV
                     RKLLREETNQFAEELKEVLIQNLPKLNTELQLLVGEFLTLENQ"
     CDS             complement(7842..8414)
                     /gene_functions="transport (smcogs) SMCOG1000:ABC
                     transporter ATP-binding protein (Score: 143.6; E-value:
                     1.3e-43)"
                     /gene_kind="transport"
                     /locus_tag="ctg37_43"
                     /transl_table=11
                     /translation="MEKDGETILAPCDLTIHAGEKIAIIGESGAGKTTLLNILYGEIHP
                     SQGQIRYQGRELTSCQLYQAGAYILQSSHVFDDLSVEENIALGQEIDQQRMDNILQETG
                     LLSLKGKVPSNQTLSGGEKQRLEIARALYHKRQFILADEVKANLDAKNQEKINQLLFSL
                     PQAVVEVIHHYTKEDLKRYDKVIHLKK"
     CDS             8448..8693
                     /locus_tag="ctg37_44"
                     /transl_table=11
                     /translation="MVKYAVSSQLISKQVLILIAEGLGRLAGIDKVGQFLKLVADVVGD
                     QINADKTSRRKVVLVGHESANHNGRHRAKCIYTVDK"
     CDS             complement(9376..9930)
                     /locus_tag="ctg37_45"
                     /transl_table=11
                     /translation="MDVHFNINDVFTKNKVLIVKEMEKSLAERKQFIDKSIQHVINNNE
                     KAFISPILYDVLISMIYKSTNRTFCDDIDPSNTLTYDADGSKKLCFRFWGTHNSPKAES
                     FNNKDNFEKCKNCWCRGMCLECVANVIDGYSSVISEDGEFLECSKPELMEYCIKQIIYL
                     SKDREKLSRLVNNFRGFIHYA"
     CDS             complement(10001..10573)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_46"
                     /sec_met_domain="PF04055 (E-value: 4e-16, bitscore: 51.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 7.8e-15, bitscore: 47.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKTIETDIGTYYFDSVNFTLSLSPISKQSSPTLDSVEDGVLKKV
                     VINISNSCNLSCSYCYADGGNYGMDNRIMDLTTADNIIQEIASKGVTQINRLILFGGEP
                     FLNIELFIYFIEKLSTLLNVVKIETVTNGTVLNKRVKEMLVKFHPYLTISLDGPEIVHD
                     RLRGRGSHRKTLRFINYLKNIDYENFE"
     CDS             complement(10630..10737)
                     /locus_tag="ctg37_47"
                     /transl_table=11
                     /translation="MEKLQVIDLEELLEFDQGYVINASCGPSHSCGGGR"
     CDS             complement(10815..11513)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_48"
                     /sec_met_domain="TIGR01716 (E-value: 2.9e-49, bitscore:
                     159.4, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIEEFVYAVRDFRRDDFNELLEKIRYLVSNRDIDGMKKLLISQM
                     EKKDKKEPFASFNTILIKIRLQDLSGETYVTDQEIVTISDYLFSAEYWGYYELLLFMNT
                     IDAFNHNTMMILAKEMCHRSDFYRDIPNNRRLLATMLLNAYITCIERNEWMDALYFEKQ
                     LKYCNFSETEMYEKLVLHYANNLYDLKKNNNRHAVLEMRKCIAATKLVDSNQIAIKFEN
                     YLQKVLDDMR"
     CDS             complement(12430..13998)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 125; E-value: 6e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg37_49"
                     /transl_table=11
                     /translation="MKKYILKYKLLNLIHIILIGFSSAFLVGASVTLSIMLNKLVESDF
                     KGFLIWLGIEFGVYLLFLADTYLIRVNQTKLIQKMTLSLRDDYINSLTRKSFSEFKNKT
                     VGEHLSILNNDIKIIEESGFESFYSLVSTVFTTFFSIIALFSYDYRIVLLSILLTLILT
                     YLPRSFAHKMEKAMKRFSIGNETFISSLTDQLLGYDTLYYSNKKEMLSIKCGEVIKKFI
                     FEKIVFIKTSSLIEIIMSLFSIISQMLVLLLTGYLIILKQVSIGSISSVGQISGNIFNS
                     LTTFNQLQVSISSVNIIFEKFGAFEKSSHYRYIDKDIEEIKLTNVGYSFKDKEIFKNIN
                     CSFEKGKNYAIVGESGSGKSTLINIILGNNKQYSGSVKYNDVEISDIEESQLFKSVSYI
                     GNITHIYHDSLRNNLTLWDNKINESEIINILKQVNLIDLIPRLDDEVSMSFLSEGQKQR
                     LGIARAYLTKTNVIIMDESMANLDRDNAFLIENQLLNDPTRMYITVSHHLQEKLLDRFH
                     SIITL"
     CDS             complement(14003..16162)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg37_50"
                     /sec_met_domain="Pkinase (E-value: 2e-14, bitscore: 45.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 2.8e-08, bitscore:
                     24.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEELITPSEKRIINRKKGEIYDYISYSNAFVPYQGWKIHISANLI
                     DYQSILDNVYHVCSIFQTPFKYINKISELFRILSKHVSQLEIGKFITIYPKNKETFLLL
                     LEELYDKIPKYTGVQILTDRSYKDSEIIFYRYGVMNARLINNERPKLKFNGTFYEDITE
                     PYYTCPPFVEDIIFNKVVDDYNIESLFHDRYQMESIIHKSGAGNVYIAIDTINEEKVII
                     KEARKKVYITEKILAIDLLLNEKCILKKLKGKVDIPNYIECFTIEGNLYLVEEFIDGQR
                     LDILKPEYNLLIKRNSSELGRYNKKVKKIISNLFLSLYKIHQEGIILEDISSSNILLTN
                     DDRVFFIDLETAYNKNDGIIVETTNECYPKNISQKNEQRDIVKMWYCIIDLLTNSTSLL
                     KYDNTGVSTLNLFYKMSLENNLPKSLRKKFINDFSIVDFKNTFIIKFIEMGLNIEKIVR
                     MQQDLTETILSHNTFEIHGKTILESIDNYKHISNMDLKFSSDPSFSSLYDNCNKSIDDL
                     IGIAILDNNFELFLNYNLDELLHDMSYYQKYYLLRLFNDTKICDRVYFIKVLNSIIKND
                     IKCIDGVKYIKSNEYFSPYLITGNSGLIIELIKFSKNNNTMKFDEWIRSLSEGISYTYA
                     KGTSLYYGLAGLGLANAWLYYYFKETSFLKTSIKICEHIFDFSIKQNTKTILIDPMSEE
                     IDYTYSKGMLGQLYFINELLNIIKE"
     CDS             complement(16247..17119)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg37_51"
                     /sec_met_domain="TIGR01716 (E-value: 2.2e-31, bitscore:
                     100.9, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDTIDIGSLTKKIRLSKKLSLKDVAGDYLSVSFLSKFERGESEI
                     SLSRFLCILENLDVSIEEIYGILSKDNPTRTEELLARVSKAFQQNNIPALKKYYYEEIE
                     KFNSTHKKIFLYNSILIDSFLISITGKKMNKKHIEVISDYLFDIDQWGKRELVILGNSM
                     SAVPTNTLNLLIKEIIYKTTLFGNNEENKKIKIDLILNGISIFLERKELNYAKFYIDLF
                     DTLTIPEVYLYERVEYNILIGTYWILIGKIEVGKKKIELALESLKNLGAENLLLMRENE
                     YEELLNSII"
     CDS             complement(17280..17369)
                     /locus_tag="ctg37_52"
                     /transl_table=11
                     /translation="MTTQNLNKLPGTIAVPMDKIRITIYCPSF"
     CDS             complement(17420..17548)
                     /locus_tag="ctg37_53"
                     /transl_table=11
                     /translation="MIGINLFLVMFCNSTITDLFLFVFTQLILHYRAIPIYENINT"
ORIGIN
        1 cgttcaacgc cttttacagg tactttttta tagttttttg aaagtgtcga tttaaactca
       61 gaaggcaatt gcgtatcttg ttggacaaca agatattgtg cagaatcttg aacaagagtg
      121 tctaaaagag ccttttgatg acttgattta gctgtgttaa gatcaggaag aacaaatggt
      181 gaagctgatt tacgattact tttcaaataa atttttgcgg atgaatcata aacgtaaata
      241 gtttcatctt tcttggtatt tttagcgagg taatttgcga cactgctacg ttcagcatta
      301 tttcctaaat caaataggaa catgatgatt ggtatagcaa aggcaaatgc aaaaacgact
      361 ataggtaaga aataattacg gctaaggaag ataccaaaaa cttttagcgt gcggatttgg
      421 ttatcattac gacgtcggtg agaggttcgc tccgctctct ttttaatagc atcatccaga
      481 gaaagtgcag tcaagactaa accatatggg acgatggtaa gaatgctgta aagtccaaaa
      541 ctttgagaga atagactgta aactagtgta aagataaagc taaggattaa tacccattta
      601 atgattttat ctttagcatc accaaggaga tggttaccta tagtaactac accaataagg
      661 agtccagaac ctataacagc aaaactttgg taagccaatg tcagtaggaa gttatttttt
      721 tctacagtga gttgtgtaaa gttgtaaact agaacttgat taatatagtc cgaagtgatt
      781 tgcaagttta ggatgaaata aaggcatagg tacagtacta aaatattacc aaaaataata
      841 caaaggactt gataaaaacc acgagcaaag tgcttgttga caatattgta aacgaatatt
      901 gtcacaattg acaataccca gaaaataaga gttcgagctt caaagaatgc tccagcagca
      961 ccagcaaaac cgtaaagaat aaaggcttca tcacgactgt gaccagcaaa gtaccgggtt
     1021 aagaagaaaa tagcaccgag gacaaaaggc atggcaaatt ggataggata gagtccacca
     1081 aaaccaagtg ttccattaat taaaaagaaa ataatactaa ttagagttgc aatttccttc
     1141 ttatttgtca tatgcatgac aaccttgtaa aggtagctgc cagaaagata gtaggttaga
     1201 aactgtattg gaattaacca aagagtagac cccagacgaa aagccagaga aattaggaaa
     1261 taatagaaga acccacctgt cgcaaaaaag tcagaatagg gtaaactacc gttggcaaac
     1321 atttttgcaa tgtaaaggtt ttgggattgt atattattgg aaaagtctgt aaagcaaggg
     1381 actgatatac tacatgcact caaaatcaga ctgaggataa ggatatgtgt tttatgctta
     1441 caaggaagtg aaatcttagt ttttttctct atctgataag aagttgattc ttttgtacgc
     1501 ccttgaattg ttacttcacc cttttcagat tgcttatcat gtgtatgaga ttgatggggg
     1561 cttcgatgat aaccttgata gctacctgat cctaggatat tgtctttgtt atatggactc
     1621 aaattaaact cctttgctgt cattttgaaa gttacaaata agggaaaaac ccaaaatctc
     1681 ttatttaaag tatatcagat aataccattt agtcaatttc tctcttattt cttacattta
     1741 agaaaaaacc gtctaaaaaa gagactgaaa taaactattt cagtctcttt tttagaagta
     1801 aatgattagg cttagttacg cccaatatta ttttttagtt ttcatcgata aagctattga
     1861 aaacttcttc aatcatatcc cattcagcat ctgaatcttc aggaattggt tgaaggtcgc
     1921 cttcagtgcc gtcctcattt tcagtgaatg agtatgcctg gatttcgatt tctccatctg
     1981 catcttcttc agcaccagct ggaaccaaaa gaacgtagtt cttaccgaat tcttcacgtc
     2041 catcaatcgt taataagatt tcaaaaagtg tttcattccc ttgttcgtct actaaagtga
     2101 tgacttcatg gtcatggttg taatcgtgat tgtgtgacat attgttctcc tttttggtga
     2161 gagtattcaa tagtgaggtg aatctagaag ttctgactgg gagttcacta gattgtcgct
     2221 cgactaatcg gtctctattt acagtttatt aaaacattcg atcgaggtag ttttgcagaa
     2281 taagttgagc agccaattta tcaataactt ttttacgctt accacggctg acatctgctt
     2341 gttcaactaa catacgttct gcctgaacag ttgtcaatcg ctcgtcttgg taatctacag
     2401 gaaggttaaa gatttcctta attttatcac cataagcttt gctagcctca acacgtggtc
     2461 cttcagtgtt attcatattt ttagggagac caacgacaaa tttatctacc tgatattctt
     2521 taacgagttc acctagacgg tcgaagccaa actctttagc ttcctcgtta attttgataa
     2581 tttcaacgcc ttgggccgta aaaccaagtg ggtcactaat agcaacaccc actgtttttg
     2641 agccaacatc aagtcccatt actcgcatta gaggtcagtt ccatttcctt taagataata
     2701 gcgaacgagt tcttcaacga tttcatcacg ttcgtatttg cgaatttggt tacgggcatc
     2761 attgtaacgc ggaacataag cagggtcacc gctcagaaca taaccaacga tttggttgat
     2821 aggattataa cctttctcag ccaacgaacg gtagacattt gtcaaagtat tactgatttc
     2881 atctttatca ccgtcgttta ggttgaaacg aacagtttca tctgtaaatc ccatactgac
     2941 accttctttc tataaggatt atctattagt ttcttattat aacataagta tacccaaaag
     3001 tgaaagacga tgaatattaa aagagatgac tgatgtcatc tcttttaata tctaataaga
     3061 ttaaacgcgt tcaactttac cagatttaag tgcacgagct gaagcccaaa cttttttagg
     3121 tttaccatcg ataagaacag taactttttg aaggttaggc ttaacgacac gtttagtttt
     3181 gttcatagcg tgtgaacggt tgtttccaga aacagtttta cgtcctgtaa agtaacatac
     3241 tttagccatt tcgtgttttc ctcctaggta gaatttatta cggatgtgct agcaccacat
     3301 accaaaatat tctatcataa gaatttaggt ttgacaagaa ctatttataa tttcttttta
     3361 cagaaaaata gtatattctt attataagaa gaataaatag ttaaaaaaag gagagaagat
     3421 gccagataat cttgctttac gcatgcgtcc acgttcaatt tcagaggtga ttggtcagaa
     3481 gcatttagtt ggtgaaggta aaattattcg ccgtatggta gaggcgaata tgctgtcgtc
     3541 aatgattctc tacggacctc caggaatcgg gaaaacctcg atagccagtg ctattgcagg
     3601 aacaacaaaa tttgctttta gaacttttaa tgccactgtc gatagcaaaa aacgtctaca
     3661 ggaaattgca gaagaggcta aattttcagg tggtttagtt ctacttctag atgagatcca
     3721 tcgtttggat aaagcgaaac aagatttttt gttaccatta ttagagaacg gaaatattat
     3781 catgattggt gccacaaccg agaatccgtt tttttctgta acaccagcca tccgtagccg
     3841 tgtacaaata tttgagttgg aaccactctc taatgaagat atcaaggaag ctattttgaa
     3901 tgttctaggg gacaaggagc gtggcttcgc ctttgaggtt cacttagatg atgatgctct
     3961 agattttatt gcgacagcta ctaatggtga tttacgatcg gcatataatt ctttggatct
     4021 ggctgtcatg tcgacaccag cttcaggaaa tgggcagcat catattacct tagacatagt
     4081 ggaaaatagc ttacaacgca gttatattac tatggataaa gacggtgatg ggcactatga
     4141 tgtcctttct gccttgcaaa aatctattcg aggatctgat gttaatgcca gtcttcacta
     4201 tgcagcacgt ttggttgagg caggggattt gcctagtcta gcacgtcgct tgactgtgat
     4261 tgcctatgag gatattggtt tagctaatcc agatgcacaa gttcacacgg tcacagcctt
     4321 ggaagctgca cagaaaatag gttttccgga ggcacgtatt ttgattgcca acgtagttat
     4381 tgacttagca ttatcaccta agtcgaattc ggcttataag gcaatggatg ctgccctggc
     4441 ggatcttaga aagtctggga atttacctat tccacgtcat ctgagagatg gacactatgc
     4501 tggaagtaag gcactgggta atgcacaaga ttataagtat ccacatgcct atcctgaaaa
     4561 gtgggttaag caacaatacc ttccagataa attaagagga gtcaattatt tccaacctaa
     4621 tgaaactggg aaatacgaaa gagctcttgg agctaataaa gaacgaatcg ataagttatc
     4681 tagataatac gagaagaatc aacgaaaacg attgcaaaaa aaatgatttt tcctcttgca
     4741 ataattttca aaagtggtat tataaaaaca tagaaattgc tgtggtatac gaatccacat
     4801 ataagtgttg accgactaat ttttgtatta tcgggagata gaggtctatt aacagtgtgc
     4861 aggctggctc acccagaagc aactgaagtt agtagcgagt cgcccacctg cttttttatg
     4921 tcgcgggttc aatacaaact gtggatcatc ggtaccaata cagcatccag cctccttagc
     4981 tcagttggta gagcagtgga ctcttaatcc atgggtcaca ggttcgagcc ctgtaggggg
     5041 catcaaactt caacagtaaa agccttgata accaaggctt ttttgcttgt cttaagagca
     5101 tttgccccat cgtttgcccc acattttttt atgagcaatc tttccagata tctctgattt
     5161 gattaaattc ctcaaaaatt ttctcttcta aagtgtgtcc atatacttct accaacattg
     5221 aaatatctct atgccctaga atttttgcaa taactccaag gtcaaaccct ttgtgccaga
     5281 ggtagcttcc ataggtgtga cgtgctcctt ttgtcgtgat aattggataa atgtccaact
     5341 catttaagag aacactcaaa gctttattga cgcttgcaat atctggaact gaatgaatat
     5401 atccaaaatg ttgaaagatc attcgatatc gatttttgat tcctaactcc atgtttgctc
     5461 tttcttgctc cgtttgtaaa aggcgcaaaa ttttgataca ctcttcgtct attggaacca
     5521 tccgaataga cgttttattt tttggtggaa caaacttatg agagagagta ttatacctcc
     5581 tgtatgtttt taacaatcct ctgtcaaaat caacctcatt ccaagttaac gctactaact
     5641 ctccaaacct catgcctgtt tttaatagaa aatagacgat ataaggaaca attgaacgtt
     5701 ggtaattgaa ttttctcttt actgctaaaa gtaaatccag atagtccttt tctgtatgta
     5761 aatatttctc ttctgtcatc tgttgttctt tggatgaaaa caactcgaca tgttgtgtaa
     5821 aatcatctat tagaactttg tcagcaattg ccatttggat gctctgatga atccccgtat
     5881 tcaatctacc aagaaaattt ctaccaactg tttgcccata cttattcata attctttggt
     5941 attcactcgc acgaatttga gtgacttttt tatttccaaa taatctttca attgtgtttt
     6001 tacggagaag atattttttc tttgtttctt ccgacctact acttggtaaa atttttagtt
     6061 caagccattc ttgatataga tcggcaagag aaatatctct agaaattctt tttcctaaac
     6121 gaagttcttg cagaatcggt tcagcttctg actctgcaag tttttttgtt ttaaaaccgc
     6181 tattatgagc aacagttttt ccttcgttac gaatttcata ggtccataaa ttactatctc
     6241 ctcgctttcg gtaacgaaca cttgccatat tacgccacct ctgttcctag aatctcattt
     6301 acaacacttt ttggaacaac catcaaacgt ttgcgattat aaaatgtata gcctcgtgat
     6361 acaagtaatt ctcttgcctg atggatgata tcatttgcag tgtgagggcg atagcccatt
     6421 tcaattaatt ctttgttgct aattaaatta ttatccatag ttatcctcct tattgatttt
     6481 ctaaagtcag aaactcacct acaagtagtt gtaattctgt atttaattta gggagattct
     6541 gtattaatac ttcttttaat tcttccgcaa attgattcgt ttcttctctc aatagtttgc
     6601 ggactcttgt ttttttcttt ttgatgctgt ctgattttaa atttggaaaa gctaatgata
     6661 acagttcagg attgcttaga aagataattg taaaggctct ttgatccact cgaatatgtt
     6721 ctagcttata aaatccgaaa ttatcaagtc gattcataat atcttgcacc atatcctccc
     6781 caatcgcttt agttctgagt tggaactcta gtctccacca aaacggattt acacccaaat
     6841 ctagcttctc ttcgcgctta tgagcaatga tttctttatt cttatcatat aacctaactt
     6901 gtacattact accgctagaa ccccaatatt tcgtctctaa ttcgccccct ctaccataga
     6961 agaccttatg ggggacacca cctttaatat gttgcaaatt aacgatttca ggcctgttga
     7021 aaatgtcaaa tgccaaatca aaacgagaca aacgtaccgt caatgaattc aatctggcaa
     7081 agtacattaa ttgcctccat actttcattc catcaaattc ttttaaagtg ttaggattga
     7141 aatcaatccg aatcaattgt tcacctccat aagtggataa ttggaaaaat ataatattga
     7201 ttgaatcata cttattaaaa tccttagcta aagtaaagac atcatctcgc acgttatcat
     7261 gtatttcaaa tgagtcaact cttgtactta ttgcctgttt cagatttttg aaaattcgtc
     7321 ttagggaacc agtgtctgta tcccagataa ccgttaatct atcaatactg acatctaacc
     7381 tctgtactaa ttctcctatt tcacatcgtt cttgaatgct tcttaaatct tgtatagaaa
     7441 ccaacaaaat tgtcccccct tcttttagat tttttaggcc tcagaaacac cgtcaaatca
     7501 acgtttgctc gttccgtcgt tctttggacg ttgtcctaag tgtacctttt tgctggctgt
     7561 tagaatagcc agcttttgct tggctagaaa ttgtctggac ggcagcctgc aggacttcgc
     7621 ctgacttcac gtcaggcgaa gtcccttgcc cttgtccaca caatttctaa atgagatttt
     7681 aggaactttg aaaactttaa aaaacgcatt cttatcactt tgaagataag aaaagagaga
     7741 acgaattgtg tcctctctcg atgttagctt ttcatcaact caagacagtt gacaaagagc
     7801 ctttcagata tacaatttgt ctatagacac tattggcata actacttttt caaatgaatc
     7861 actttatcat agcgcttcaa gtcttccttg gtgtagtggt gaatgacctc caccacagct
     7921 tgaggaagtg aaaagagcag ctggttgatt ttttcttgat ttttggcgtc caggttagcc
     7981 ttgacctcat ctgctaggat aaactgtcgc ttgtgataga gagcacgggc gatttcaagg
     8041 cgctgttttt caccgcctga taaagtttgg ttgctgggta ccttgccttt taggctgagg
     8101 agccctgttt cttgcaagat gttatccatt ctttgctggt caatttcctg tcccagagcg
     8161 atgttttcct ccacagataa atcgtcaaaa acatgactag attgcaagat ataggcacca
     8221 gcctgataga gttgacagct ggttagttcc cgtccttgat aacgaatttg cccctgacta
     8281 ggatggattt ccccgtatag gatgttgagc agggtggttt tgcccgctcc gctttctccg
     8341 atgatagcaa tcttttcccc agcgtggata gtcagatcac aaggagctag aatggtctcc
     8401 ccatccttct ccacactgac ctgctccaac tggataggaa agacagattg gtcaaatatg
     8461 ctgtcagtag ccaacttatt tccaaacaag tcttgatact tatcgcagag ggacttggca
     8521 gacttgcggg tattgataaa gtaggacagt tcttgaaact ggtagccgat gttgtgggag
     8581 accagataaa tgccgacaaa actagccgca gaaaggtagt tctggtaggt catgaatccg
     8641 ccaatcacaa tgggcgccac agagcaaaat gcatctatac tgttgataaa taaactgttc
     8701 agtgaccgtt gcttttcgta ggacacttct tcttgcaacg cctgttctag gtctttagaa
     8761 aatctcttga aaaacaaatt ctggccctga taatgacgaa taggagcaac acctgcaatc
     8821 atattgttga cacgggcgat ataattctga tttgccaggg atttttgctc cgcaatccta
     8881 tccaaacgct tcgaacccag tccgctacac aaaactggta ccgagtaaaa gatgataaac
     8941 aataacccca gatagaaatt ggtccagagg gcatatgcga tggaaacgac tgtaaaacct
     9001 agcgaggata cgataatgac ggtcggctct atatagctat tttccaactg ttggacatca
     9061 ttttccagat cagacagcac ctcctcatca ggaatctgac ggctgtataa aaaagtccga
     9121 aaaatagcgc gttttatccc aaccttaaag tcagtcatca aacgagcata gtaatagcgc
     9181 ttcccagcca agcccaggac aagcaccaga ttgcccccaa tcccccagag caaaatctgc
     9241 cagaggagat gcaactggcg gttggtaaaa ctagcgacga tatactggat aagggcaggg
     9301 gtgataatgg cctctaacca agtgatgacg atggctagaa aatagaaggt gagatgtttt
     9361 ttcgttacat aactcctaag catagtgtat aaacccccta aaattattta ccaacctaga
     9421 taatttttct ctgtccttgg ataaatatat aatctgttta atacagtatt ccatcagttc
     9481 tggtttagag cattcaagaa attccccatc ttcactaatt acagaagaat atccatcaat
     9541 aacattggca acgcattcca agcacatacc tctacaccag cagtttttac acttttcaaa
     9601 gttatctttg ttgttaaatg attccgcttt aggactgttg tgagttcccc aaaatctgaa
     9661 acatagtttc ttactaccat ctgcatcata agttaatgta ttcgaagggt caatatcatc
     9721 acaaaatgta cgattcgtac tcttgtatat cattgatatt aatacatcat ataaaatagg
     9781 actgataaat gccttctcat tgttgttgat tacatgttga atggatttat ctatgaactg
     9841 ttttctttca gccaaacttt tttccatttc tttcacaatt agcactttat ttttagtaaa
     9901 aacatcattt atattaaaat gcacatccat atcagtaaaa tattgaaaga tatcttctct
     9961 acttagacca ttttttgatg aagtctagta tatgtcgagg ctattcaaaa ttttcataat
    10021 caatattctt taaataatta ataaaacgta atgtttttcg atggctccct cttcctctga
    10081 gtctatcatg aacaatttct ggtccatcta aacttatggt taaataagga tgaaatttaa
    10141 caagcatttc tttaacacgc ttatttaaaa cagtaccatt agtaactgtt tcaattttca
    10201 ctacatttaa taatgtagat aatttttcta taaaatatat aaataattct atatttaaaa
    10261 aaggttctcc cccgaaaagt atgagacggt tgatttgtgt aactccttta cttgctatct
    10321 cttggataat attatcagca gtagttaaat ccataatacg attatccata ccatagttac
    10381 caccatctgc ataacaatac gaacaagata aattacaact attagaaata tttataacta
    10441 ctttttttaa tacaccatct tcaacagaat ctagagttgg tgaactttgt tttgaaatag
    10501 gtgacaaaga taaagtaaaa ttaacagaat caaaataata tgttcctata tctgtttcta
    10561 ttgtctttat cataattatc ctccagacta aaaactgaga tgaggaatca ctcctcatct
    10621 cggaagaagc tatcgaccac cgccacaaga atgacttgga ccacagctag cattaattac
    10681 atacccttga tcaaactcta aaagttcttc aaggtcaatc acctgaagtt tttccatggt
    10741 ttttacctcc tttatttgat agtttcatta tataacctta tcagaagagg ataatatttt
    10801 cccttatacg caattcacct catgtcatct aatacttttt gtaaataatt ttcaaatttt
    10861 atagctattt gattgctatc taccaatttc gtggcagcaa tacattttct catttccaaa
    10921 acagcatgtc gattattatt tttctttaga tcatataaat tattagcata atggagcact
    10981 agtttttcat acatttcagt ctctgaaaag ttacaatatt ttagctgttt ttcaaaataa
    11041 agagcgtcca tccattcatt gcgttcaata caggtgatat aagcattgag caacatagtt
    11101 gccaataaac gtctattatt tggaatatct ctataaaaat ccgaacgatg acacatttct
    11161 ttggctaaaa tcatcattgt gttatgatta aaagcgtcta ttgtattcat aaacagtagc
    11221 aattcataat aaccccagta ttccgcagaa aacaagtaat cactgatagt aacaatctct
    11281 tggtctgtta cataagtttc tcctgataaa tcctgtaatc ttattttaat caaaattgtg
    11341 ttaaatgaag caaaaggttc ctttttatcc ttcttttcca tttggctaat taatagcttt
    11401 ttcattccgt ctatatcacg atttgatact aaataccgaa tcttttctaa aagttcatta
    11461 aagtcatctc tgcggaaatc acgtacagcg taaacaaatt cttcgatagg catatgtatt
    11521 gcatctaacg ctaaaaaaat ttgctgatgg ttaaatcagc ctcatcattt tcaaatcttg
    11581 agagatggga acttgaaaga cctgattttg caacattttt taaagataaa cctcgagatt
    11641 ctctaaattt tttaaaaatt tttccatatt tcattctagt cacctcctaa attacttata
    11701 agggaaattt cttcacaaat attaaaaata ttatatcata taagaaaacg aaaagaggta
    11761 tttaccatga ataaaaaagc attgtttagt ttgttgtttg taatacttga aggtattatc
    11821 gttatcggag taggttagcc aaatgataaa gagattaggc aagaaacctt aaaaataaaa
    11881 aatagcttag aattgcgtca ttataaacgt tgattccaag ctatttttgg ttattaaaat
    11941 tttaatcaga agggtaaact tgtagttttt gcccaacctc tcttgatttt atggaaaaag
    12001 aatcccgtat tttggatacg aaatgctttc aataagtgta aatcagtttt aacgtttact
    12061 aaatttcgat gctttacgag cctttttcaa gcctggtttt caaagcaagt tggaaacctt
    12121 tatgagtcat tcgtttttgc cccacttttg ccccattttg aaataattat atttaaaaat
    12181 gctccaagta tcttctaaaa ataacttata tttcaacatt tttgattatt ttcaatatga
    12241 aaaattcata caaattcatg tagggggcat catactatac ataaaaaaag cctttaaata
    12301 aaggcttttt tacttgtctc aagaggaaat gtcccatcat ttgtccacga aataatttcc
    12361 aaacttttga taaatattat ttttgtataa attaattttt gttgtgtata gtaacattga
    12421 attctcaatt taaagtgtaa taatactatg aaatctatct agtagttttt cctgtaagtg
    12481 atgagagaca gtaatgtaca tccttgtagg atcgtttaat agctggttct caattagaaa
    12541 agcgttatct ctatctaaat ttgccataga ttcatccatt attattacgt tagttttagt
    12601 aagataggca cgtgcaatac ctaatctttg cttttgccct tctgataaaa aagacatact
    12661 tacttcatca tctaatcgtg gaattaaatc tattaaatta acttgtttaa ggatattgat
    12721 aatttctgat tcatttattt tattatccca aagtgttaaa ttatttctaa gagagtcatg
    12781 ataaatatga gtaatatttc ctatatatga aacgctttta aacaattgag attcttcaat
    12841 atcagatatc tctacatcat tgtattttac acttccacta tattgcttat tatttcctaa
    12901 aattatattt attaaagttg attttccact acctgactct ccaactatgg cataattttt
    12961 tcctttttca aaactacaat ttatattttt gaaaatttcc ttatctttga aggaataccc
    13021 gacattagtt aacttgattt cttcaatatc tttatcaata tatctataat gggaactctt
    13081 ctcaaaagct ccaaattttt caaatataat atttactgat gatattgata cctgtaattg
    13141 attaaacgta gttaatgagt taaatatatt tccggaaatt tgtccgactg atgatattga
    13201 accaattgaa acttgtttta aaatgataag ataacctgtt aaaagtagta ctaacatttg
    13261 agaaataatt gaaaataaac tcattattat ttcaattaag ctactagttt taataaatac
    13321 tattttttca aaaataaatt tttttattac ctctccacat ttaattgata acatctcttt
    13381 tttatttgaa taatatagcg tatcatatcc cagtaattga tctgttagtg atgaaataaa
    13441 tgtttcatta cctatagaaa atcttttcat agctttttcc atcttatggg caaaacttcg
    13501 tggaaggtaa gttaggatca aagtaagtag tatagataaa agcactattc tataatcata
    13561 actaaacaga gcaataattg aaaaaaaagt tgtgaaaact gttgaaacta atgaataaaa
    13621 gctttcaaat ccgctttctt cgataatttt tatatcgtta tttaaaattg acaagtgttc
    13681 tccaacagtc ttatttttaa attcactaaa cgattttcta gttagactgt taatataatc
    13741 atctctgaga gaaagagtca ttttttgaat taatttagtc tgatttactc taattaagta
    13801 tgtatctgcc aaaaataaca aataaactcc aaattcaatg cctaaccata tgaggaagcc
    13861 tttaaaatca ctttcaacca atttatttaa catgattgag agtgtgactg atgctccaac
    13921 taaaaatgca gaactaaatc ctattaatat tatatgtata agatttagca gtttatattt
    13981 tagtatatat tttttcatta tgttattcct taattatatt tagcaactca ttaataaagt
    14041 acaactgccc caacattcct tttgaatatg tataatcaat ttcttcggac atcgggtcta
    14101 tcaatatagt ttttgtattt tgtttaatag aaaaatcaaa aatatgttcg caaatcttaa
    14161 tactcgtttt aagaaatgaa gtttctttaa aataataata aagccaagca tttgccaaac
    14221 ccaatcctgc taatccataa tacaatgagg ttcccttagc atatgtataa ctaattcctt
    14281 ctgataaact tctaatccat tcatcgaact tcattgtatt gttattttta ctgaacttaa
    14341 taagttcaat gattaaccca gagttaccag ttattaaata tgggctaaaa tactcattgg
    14401 attttatata tttcactcca tcaatacact taatatcatt tttgatgatt gaatttagga
    14461 cctttataaa gtagactcta tcacatattt tagtgtcatt gaaaagtctg agtagataat
    14521 atttttgata gtagctcata tcatgtagta gttcatctaa attataattt aaaaaaagtt
    14581 caaaattatt atcaagtata gcgattccga ttaagtcatc tatactttta ttacaattat
    14641 cataaagaga agagaaactg ggatcgctag aaaattttaa atccatatta ctaatatgtt
    14701 tataattatc aattgactct aatattgttt ttccatgaat ttcaaaagta ttatgggaaa
    14761 gtatagtttc tgttaaatct tgttgcattc taactatttt ttctatattt aaacccattt
    14821 caataaattt tattataaat gtattcttaa agtccactat actaaaatca ttaataaatt
    14881 tttttcttaa agatttaggt aaattattct ctaaactcat tttataaaat aaatttaagg
    14941 tactcactcc tgtattatca tattttaaaa gactagtaga attagttaat aaatcaatta
    15001 tacaatacca cattttaaca atatctcgct gttcattttt ttgagaaatg tttttgggat
    15061 agcattcatt tgtcgtctca acaataattc catcattctt attatatgcg gtttcgagat
    15121 caataaaaaa tactctatca tcatttgtta aaagaatatt acttgaagat atatcctcta
    15181 atattattcc ctcctgatgg attttatata aacttaaaaa tagattagaa attatttttt
    15241 ttactttttt attatatctt cctaactcgc tagaatttcg ttttatcaac aaattatatt
    15301 caggctttaa aatatccaat ctttgtccat caatgaattc ctcaacaaga tataaatttc
    15361 cctcaattgt aaagcactca atgtaatttg gaatatcaac tttacctttc aattttttta
    15421 gaatacattt ctcatttaaa aggagatcta ttgctaaaat cttttctgta atatatactt
    15481 tttttctagc ttcttttata ataacctttt cttcattaat agtatcaatc gcaatatata
    15541 cattacctgc tcctgattta tgaataatag attccatttg atatctatca tggaataaag
    15601 attcaatatt atagtcatct acaactttat taaatatgat atcttcaaca aatgggggac
    15661 atgtatagta tggttccgtt atatcttcat aaaaggttcc attaaattta agttttggtc
    15721 gctcattatt aattaaacgt gcattcatta ctccatatct ataaaaaatt atttctgagt
    15781 ctttataact tctatctgtc aaaatttgaa ctccagtata tttgggtatc ttatcatata
    15841 gttcttccaa taataataaa aaagtttctt tgtttttagg atatatagtt ataaattttc
    15901 caatctctaa ttgcgaaacg tgttttgata aaatacggaa taactcagat attttattga
    15961 tatacttaaa tggcgtttga aaaatagaac aaacatggta aacattatct aaaatagact
    16021 gataatctat taaattagca gatatatgaa ttttccaacc ttgataagga acaaaagcat
    16081 ttgaatatga aatataatca tatatttccc ctttttttct attaatgatt ctcttttcac
    16141 ttggtgtaat tagttcttcc atgataaatc tcctattaaa aataaaatac tgctgtataa
    16201 ctatataact agtgtaacag cagtatttta tttttagtaa aaagtgtcat ataatagaat
    16261 tcaataattc ttcatattca ttttctctca ttagcagtaa attctcagca cctaaatttt
    16321 tgagggattc caaagctagt tcaattttct tcttgccgac ttctatttta cctataagta
    16381 tccaatatgt acctattaat atattatatt ccactcgctc atagagataa acttcaggaa
    16441 tggtaagtgt atcaaaaaga tcaatataga acttggcata atttagttct ttcctctcta
    16501 aaaatattga gattccgttt aaaataagat caatttttat ttttttattt tcctcattat
    16561 taccaaataa agtagtctta taaataattt cttttattaa taaatttaat gtatttgtag
    16621 gcaccgctga catactatta cctaatatta ctaactctct tttcccccat tgatctatat
    16681 cgaaaagata atcagaaata acttcaatat gttttttatt cattttttta cctgttatcg
    16741 atattaaaaa tgaatcaatc aaaatagaat tatataaaaa tatttttttg tgtgttgaat
    16801 taaacttttc tatttcttca taataatatt tttttagagc aggtatgtta ttttgttgaa
    16861 atgccttact gacccttgct agtaattcct cagttcttgt aggattatct ttcgataaaa
    16921 ttccgtaaat ttcttcgata cttacatcca aattttccaa tatacaaaga aaacgagaaa
    16981 gtgaaatctc agactcgcca cgttcaaact tagataaaaa cgaaaccgaa agataatcac
    17041 cagcaacatc ttttaatgaa agtttttttg ataatctaat ttttttcgtt aaagaaccta
    17101 tgtcaatagt atcaatcata aaataactcc ttttatacaa ttataacaaa aaacgcaaac
    17161 ataatgcagt ctgcgttaac cttttgaata ttaggagtat attgtaatac gaagtctatc
    17221 tttaaattca aaagaatcac ttggtaaact gttcaaaatt tgaataatca tttttctcct
    17281 taaaaacttg gacagtaaat cgtaatacga attttatcca ttggaactgc aattgttcct
    17341 ggtaacttat ttaggttttg agtagtcatt tttttctcct ttctaaatct tatagacata
    17401 ttatatattt ttgcaataat taagtattaa tattttcata tataggaatt gcccggtagt
    17461 gtaaaataag ttgtgtaaac acaaaaagga ataaatccgt tatagtagag ttgcaaaaca
    17521 ttactagaaa gagatttatt cctatgactc
//
