LOCUS       gnlProkkaPDEGELGB_69   16898 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PDEGELGB_69.
ACCESSION   gnlProkkaPDEGELGB_69
VERSION     gnlProkkaPDEGELGB_69
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 13:41:58
            Original ID  :: gnl|Prokka|PDEGELGB_69
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 4421
            Orig. end    :: 21319
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16898
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12284]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12284
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..16898
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16898
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             2420..3646
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Metallophos_2"
                     /gene_functions="other (smcogs) SMCOG1230:Nuclease SbcCD, D
                     subunit (Score: 253.4; E-value: 8.6e-77)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_4"
                     /sec_met_domain="Metallophos_2 (E-value: 1.4e-10, bitscore:
                     31.8, seeds: 57, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNEEVVMKFLHTSDWHVGRTLNGWSLLEEQEWAFQQIVDLAISEK
                     VDGVIISGDLYDRAVPPVDAIKLFNKTLARLVLEEQIPVYAISGNHDGAERLHFGRDFF
                     QHQGLHLSTRLEEAFEPIELENCQIFLLPFIDPIDARIYYKDDEGKEIQGIGDALTYIL
                     EDMEKAFDPDKAHVLVTHFAVSKKDDSDGQGLRELMLSETSNTVGGLTNVTSDLFKSFD
                     YVALGHIHTRFASPTKRVQYSGSPVAFNVKEAKRKEEKGVYILELDASGDMSQTFHTLE
                     VKRPIVALQESFETLMSPEFYKNQPCQKAWFAFDIQLSSRKELEGINVRARLEEIYGTD
                     IVEITFSRLGDVREENLTVDQHLKDLEMQSPQEIVFDFYQTVTGGDVLSERQTALVESV
                     FEEIERSRQ"
     CDS             3643..6822
                     /gene_functions="other (smcogs) SMCOG1218:Exonuclease
                     (Score: 497.2; E-value: 1.7e-150)"
                     /gene_kind="other"
                     /locus_tag="ctg38_5"
                     /transl_table=11
                     /translation="MRPVQLELTNFGPYRKEVINFTQFDHAPLFLIGGDTGAGKSTLFD
                     AMTVALFATTSGDRNVEEMRSTFAGPEDDLTKVTFYFQQGNHLYRIDRVLQQERAKQGG
                     GTTMQKATASLVIVDKIGGQEIEKLGDKIKEVSDQIEQILGLNAEQFKQIILLPQNDFS
                     RFLKEDSKTKTQILKKIFGTGIFDHFQKSLEERLRQSNKDMEKRQAQLDGHFASQVWSE
                     EELSVLEQTPASEKLTRLEEFLSQRQENVTKQKSILKAAHEDLAQLQKSLQTAQDLAKI
                     FQELEQAKERYRLEIEEGAQGQAEAKVHLEELQFAQGLQETIRTLKQYRKQLMQLEQDL
                     EIAQEALSEKQQAFEDVKAKKEELTVQSKDFLQKEEELETWKENIIYAQSLAQEQEKIK
                     RSTTNYKQLEETYQQARKEVEMLNKSLSDLEANRLSLDSLHEAEKLFQIVGYSVENQLA
                     QDLKEIENLNQELTKTEKRHQTLSFDIDQAQEILKELEEELRRTLVSRRQLIIVQLQAE
                     LEEGHPCMVCGALEHPNVGGAQADEVALKNLMDQVEKLQAQKEKQVATLSNRQATLSEV
                     ASKRQDLLDQVAKVKATLEKHYQELEEHVKGRFDFDFSIDYETDRGQALLLKVEQYYQE
                     LQKRYDKEETDYIRYQDELGKAQKKATDLAKTYQEAKAVLDQAQERLEDLQEAHPELES
                     VEVYQERISLAHQELNLYNKQVKENSEAYNQLHADIKGIKGQIESITKSKDKVNQDVKR
                     LSAELEQSLKAEGALANDLEQVELWLIEVNNQAIPMLQAKLTTYATLKQELQAQIHKGQ
                     ELLQNQEQPDLDSLAQAVQNCQEIYDRQLAQFSVMEKGLKDATATYQAAKTLQDSNQEA
                     FKAHQELSDLVKVVKGENTALTGRLNLEVYVIRQYFQQILDYANANYIGLLTDNRYSFV
                     LSEEGRRARDHFGLDINVYDQLTGSERSVKSLSGGETFIAALAIALSLSEVVQNTSKGA
                     VVEALFIDEGFGSLDKEALTKAISVLEQIGENRMVGVISHVDDMKEGIAQQLVIIKSHD
                     GSSRIKIVDKG"
     CDS             7222..7734
                     /locus_tag="ctg38_6"
                     /transl_table=11
                     /translation="MAAAKLVEDKQAEDKASILSSDTVKEFLTQYYTKEKLGENNTRIQ
                     PYMTESAYSQELTSQNDAMNQVYKDYILDYHFEKADIFVNQTTNQAIAMVSYNVTYVSD
                     LKNANQSKTNQTETRTVNLNYSKLPGKLLVNQVQVWKSGLDDLDKATPKTLEESSSVPS
                     LPNTTTK"
     CDS             7887..8045
                     /locus_tag="ctg38_7"
                     /transl_table=11
                     /translation="MTKHSYVAKFKRKDETVFTKRFLASDLFEAVEHALEYATKRDILY
                     LDLGHAG"
     CDS             8224..8790
                     /locus_tag="ctg38_8"
                     /transl_table=11
                     /translation="MNCTPKVRQKKSNFRGVFIMKLTYEDKVQIYELRNQGYSLDQLSN
                     KFGINISNLSYMIKLIDRYGIEIAKKGKNRYYSPELKQEMIDKVLYKGYSQDRVSLEYA
                     LPNRGTLPNWLAHYKKNGYTIVEKTRGRLSKMGRKPKKKLEEMERLQAENEYLRAENAV
                     LKKLRELRLREEKEQEEKRKLSEDW"
     CDS             8784..9620
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 266.7; E-value: 3.2e-81)"
                     /gene_kind="other"
                     /locus_tag="ctg38_9"
                     /transl_table=11
                     /translation="MVTEFSLDMLLKIIKLARSTYYYHLKQLDQNDKDYDIKAEIQAIF
                     TEHKGNYGYRRMTLELRNRGIVINHKRVQRLMKVLGLTARIRRKRKYSSYQGEVGMKAE
                     NLIQRQFEASKPLEKCYTDVTEFAIPASSQKLYLSPILDGFNSEIIAYNLSKSPNLIQV
                     KAMLEQAFTEKHYKNTILHSDQGWQYQHDFYHHFLEEKGIQPSMSRKGNSPDNGMMESF
                     FGILKSEMFYGYEKTFKSIEHLEQAIADYINYYNNKRIKVKLKGLSPVQYRTKSFT"
     CDS             10001..10720
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_10"
                     /sec_met_domain="TIGR01716 (E-value: 8e-52, bitscore:
                     166.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MFILDEINMPIDEFMYAVHDFHRDELNELLSKVRHFVSTRDVEGM
                     KKLLYSQMELEDRREKFHQINIILLKIRLQDLSGETYYTKDDLTYLTDYLFSVEYWGYY
                     ELLIFSNTLDVLNHDVFMVLAREMFRRSDFYKEIPNNRRLISTMLLNGYITCVEREKFM
                     DALYFEKQLNQCFFIETEVYERLVFKYAQNLYQYKEDGNVKAIIEMKKCVGAMKLAGSH
                     HLAKTYEGHLEKILASS"
     CDS             10803..10895
                     /locus_tag="ctg38_11"
                     /transl_table=11
                     /translation="MSKELEKVLESSSMAKGDGWKVMAKGDGWE"
     CDS             10965..12284
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg38_12"
                     /sec_met_domain="Streptide_RRE (E-value: 3.1e-25, bitscore:
                     79.0, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 1.5e-20, bitscore: 64.6,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 1.5e-07, bitscore: 22.2,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 4.4e-14, bitscore:
                     43.1, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 2.2e-07, bitscore: 21.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MMTISEDFLFRLEKFGGILINKVTFDRIELDESEAYFLYLVQNHG
                     FEIATSFFKKEIKAGKLERVLLLNIYSDNNIEGSSKNPDETLQNARKHVAKLKKHNILS
                     FPLELVIYPSMYCDLKCGFCFLANREDRNAKPAKDWERILRQAKDNGVLSVSILGGEPT
                     RYFDIDNLLIACEELKIKTTITTNAQLIKKSTVEILAKSKYITPVLSLQTLDPKLNFEL
                     MGVRPDRQIKLAKYFKEVGKKCRINAVYTKQSYEQIIELVDFCIENKIDRFSVANYSEV
                     TGYTKIKKKYDLADLRRLNEYVTDYITQREANLNFATEGCHLFTAYPELINNSIEFSEF
                     GEMYYGCRAKYTKMEIMSNGDILPCIAFLGVNQTKQNVFEKDLLDVWYDDPLYGGIRSF
                     RTKNSKCLSCGLLKICEGGCYVNLIKEKSPKYFRDPVCNL"
     CDS             12281..13372
                     /locus_tag="ctg38_13"
                     /transl_table=11
                     /translation="MSKKIFNLYGMNMFLSGLPYYFVGILLLKHLGFSFTEIATLSVIT
                     ELCGSVFDIPLSYISSKIGYKKILAISNLLLILALWGLLFGKSNIIYISAIFFGLSESL
                     SSGVLISYNFEIIDDEVVYKSFLKNLNTLKYIFIAIITIISPPLLHRNYIYPIIISIVF
                     VIFSLLYLIGLPEIKKEQNNKQKFFSLDNIQNIPWLLIILGVAFSTLIMISNSYAGIFL
                     NEQGLSLDMLGIILFMFNISMALGSYLKIKFEVSLMLPVLAILMFFQTNLIIQIIILLL
                     MRVLNSNYNNHFYYKFNMSIEKNRAVSWSVYNLFISISFMLADFLAGIFADNFSIRSNY
                     LIFGIVALCCLVSYSFSNREKRT"
     CDS             13457..14068
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg38_14"
                     /sec_met_domain="TIGR04085 (E-value: 3.6e-16, bitscore:
                     49.8, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.1e-13, bitscore: 41.9,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNDMLGIEYMSVMVICPTGRANDGSILADKKQWYPVFLDLTERIS
                     KGEFKVKFKIVPPNESDVFLTHYFPLAFYNRSDLLENVWHQKVDINFDKPREISCQAGV
                     RACSINHKGDVYGCDLMNGIDELVAGNVKEQKFSEIWHHSAVFNKLRSITFDDISGKCS
                     ECPLPWCGGGCRCSALELDGTLLGSDLACFYEQKGGGVVV"
     CDS             14065..14154
                     /locus_tag="ctg38_15"
                     /transl_table=11
                     /translation="MKEHFVIRGKRDFIVNKVADEYIGYDLLD"
     CDS             14384..15295
                     /gene_functions="transport (smcogs) SMCOG1086:MATE efflux
                     family protein (Score: 99; E-value: 4.5e-30)"
                     /gene_kind="transport"
                     /locus_tag="ctg38_16"
                     /transl_table=11
                     /translation="MIDSKEINKFAFPLVLTNIGQVIIGQIALHFAVNNSSIALSGISI
                     IQNLLFAFGGLLGAFSLSFNIKSSKAYSNRQTNRFDDLLKSNLTLDLIIGVAFAVFVII
                     FGNVILKQLYGFKGQLLSLSTIYLVFMSPYIGLTLLNFSLTNLLRVQKKTKPIMWVGLI
                     SSLIDVVLNYVLVPQIGIKGAAISTIVSLAFISLSYLFMVYPMILKALSITSTTKFELI
                     TFGIPLVGQEILESVLFIMVFDALMSRLGVELLAIYAVISQLLSIVSVPSFVYSTTVSI
                     YLPEAEKIGEVNVFLKNIFKNS"
     CDS             complement(15395..15694)
                     /locus_tag="ctg38_17"
                     /transl_table=11
                     /translation="MCTASFGIAKEAYKFRKNLITKEEFLLNSQILCVEVSVSALSSIL
                     GHAVIPIPILGSVIGNNIGTFLYEIAKDNLTMKEKLLIADYFKEIQEYNYFLDN"
     CDS             complement(15854..16123)
                     /locus_tag="ctg38_18"
                     /transl_table=11
                     /translation="MQWKEVNQFFETESIKLSDIEPSKVSYREVQRNQINTTIYNEKGN
                     IKDIDTSIIRDMYDKSKPTLKQGAYISAIAASLEGGYCIYNSNN"
     CDS             complement(16293..16394)
                     /locus_tag="ctg38_19"
                     /transl_table=11
                     /translation="MEEVRKLRQEKAELEKENDFLKKAAAFFAKEID"
ORIGIN
        1 gtcgtatgta tgcgaaacca gctgatatcg aagaatacct cacaactggt aaactagttg
       61 atctttcaag cgttagtgat aaacactttg cttcaggtaa cctaactaac aaacctcaaa
      121 aaccttatat ttcatgtgaa tacatgcaca taatgggtaa ctctggtggt ggattgcaac
      181 tctacactga cttagagaaa tatccagaat accaaggtgg atttatttgg gacttcattg
      241 accaagctat ttacaaaaca cttccaaatg gtagcgaatt cctatcatat ggtggtgact
      301 ggcatgatag accttctgac tacgaatttt gtggaaatgg tatcgtcttt gcagatcgta
      361 ccctaactcc aaaacttcaa acagttaaac atctttactc taatattaag attgctgttg
      421 atgaaaaatc agtaactatc aagaatgata atctcttcga agatctttct gcttatactt
      481 tcctagctag agtttacgaa gatggtagaa aagttagtga aagtgaatat cactttgatg
      541 ttaaaccagg cgaagaagca acattcccag ttaactttgt agtcgaggct tcaaattctg
      601 aacaaattta cgaagttgct tgtgttctga gggaagcaac tgaatgggct cctaaaggtc
      661 atgaaattgt tcgtggtcaa tatgttgttg aaaagattag cactgaaaca ccagttaaag
      721 cacctttgaa tgttgttgaa ggcgacttca acatcggtat tcaaggacaa aacttctcaa
      781 tcttgctttc acgtgcacaa aatactttag tatctgctaa gtataatggt gttgaattca
      841 ttgagaaagg tcctaaactt agcttcactc gtgcttacac tgacaacgat cgtggtgctg
      901 gatatccatt cgaaatggca ggctggaagg ttgctggaaa ctatagtaaa gttacagata
      961 ctcaaattca aatcgaagac gactctgtta aagtgactta tgttcatgaa ttgccaggct
     1021 tgtctgatgt cgaagttaag gtaacttatc aagttgatta caagggtcga atctttgtta
     1081 ctgcaaacta tgatggtaaa gcaggtttgc caaacttccc tgaatttggt ctagaatttg
     1141 ctatcggttc acaatttaca aaccttagct attatggata cggtgcagaa gaaagctacc
     1201 gtgataaact tcctggtgcc tatcttggtc gatatgaaac atctgttgaa aagacatttg
     1261 ctccatatct aatgccacaa gaatctggta atcactatgg tactcgtgaa ttcacagtat
     1321 ctgatgataa ccataatggt cttaaattca ccgcacttaa taaagcattc gaattcagtg
     1381 ctttgcgtaa cagtactgaa caaattgaaa atgctcgtca ccaatatgag ttgcaagaat
     1441 ctgatgctac atggattaaa gttcttgctg ctcaaatggg tgtaggtggt gacgacacat
     1501 ggggtgctcc agttcatgac gaattcttgc ttagctcagc agatagctat caattaagct
     1561 tcatgattga accactaaat taggtagtta ttaagaatct agttgtacat tatttgataa
     1621 ttataaaaga gaagctttgg aggcttctct tttcatgttt taaaggagat taaatcatta
     1681 gtgtgttagt atcttccaaa aatctacaag cggtactgat tagcactcca acacattata
     1741 aatatatttc aagtgattta agataggaat tagctattac cggtgtttct ctaaaagaaa
     1801 taaaaatcat accattcgtt cagatggaat aatgcatgtg acttataaaa aatctcaagt
     1861 agggaaatag taaatactac atgcctagtt ccaagtcagc taacaagcta cggataaaaa
     1921 aagcctagaa taaagtaaaa agtcaggagc ccttagggtt cggattattt ttaggttttc
     1981 atagtgaaaa atttaaaaag gatcggtact gacaataacg aaaagtgagt aaatattatt
     2041 gcctaaaata caagatgtgc actagtacca acctatatga taatgcttag aatctataaa
     2101 agtcaattaa aagaatagat aatattgatt ttcttggtta gaggtattta aattacttaa
     2161 ccaattgagg cagggtaatc tagactatat tgattactac aacaacaaat gcattaaggt
     2221 aaaactaaaa ggactcaatc ctgtgcaata cagagctaaa tcctttgctt acataaattg
     2281 tctaactttt tggggtcagt acaggatagc ttgggagaga ttttttgatc tttacagcta
     2341 aaaaacggga aaactatcaa agcctgtgaa acttttaagc agtatttagc ttgataaggt
     2401 acaatagaag taagacaaaa tgaatgagga ggttgtcatg aagtttttac atacgtcaga
     2461 ttggcatgta ggacgaaccc tcaatggctg gtctttgttg gaggagcagg agtgggcttt
     2521 tcaacaaatt gtggatttgg ctattagcga aaaagtggat ggggttatca tttctgggga
     2581 cctctatgac cgtgcggtgc cccctgtgga tgcgattaag ctttttaata agaccttggc
     2641 ccgcttggta ctggaggagc agattcctgt ctatgcgatt agtggtaatc acgatggggc
     2701 tgaacgttta cattttgggc gtgacttctt tcaacatcag ggccttcatt taagtacacg
     2761 tttggaggag gcttttgagc ccattgagtt ggagaattgc cagatttttc tgctgccttt
     2821 tatcgatcct attgatgctc gtatttacta taaggatgat gagggaaagg aaattcaggg
     2881 gattggtgat gccttgacct acattcttga ggatatggaa aaagcttttg atcctgacaa
     2941 agctcatgtc ttggtgacgc attttgcggt ttctaagaag gatgatagcg atggtcaggg
     3001 tcttcgagaa ttgatgttgt ctgaaaccag taatacggta ggtggtctta ccaatgtgac
     3061 cagtgacctt ttcaagtctt tcgattatgt tgccttaggg catatccata cgcgttttgc
     3121 tagtcctacc aagcgcgtgc aatattcagg cagtccagtc gcctttaatg tcaaagaagc
     3181 caagcgtaag gaagaaaagg gtgtctatat tcttgaattg gatgcgtctg gtgatatgtc
     3241 tcagaccttc catactctag aggttaaacg gccgattgtg gctttacagg aatcttttga
     3301 aaccttgatg tcacctgaat tttataagaa tcaaccttgt caaaaagcct ggttcgcctt
     3361 tgatattcaa ctgtctagtc gtaaggaatt agagggtatc aatgtgcgtg cccgactgga
     3421 agagatttat gggacagaca ttgtagaaat tactttcagt cgtctgggtg atgttaggga
     3481 agaaaacttg accgttgatc agcacttaaa agatttggaa atgcagtcgc cccaggaaat
     3541 cgtatttgat ttttaccaga cagtaactgg gggcgatgtc ttatctgaga gacagactgc
     3601 ccttgtggaa agtgtttttg aggagattga gaggagtcga caatgagacc agtccagtta
     3661 gaattgacca attttggacc atatcgtaag gaagttatta atttcactca gtttgaccat
     3721 gctcccctct ttttgattgg aggggataca ggggctggta agagtactct ctttgatgcc
     3781 atgacggtag ccttgtttgc tacgaccagt ggtgatcgta atgttgagga gatgcggtca
     3841 actttcgctg gtccagagga tgatttgacc aaggtgactt tctatttcca acaaggcaat
     3901 cacctttatc gcattgaccg agttctccag caagagaggg ccaagcaggg tgggggcact
     3961 accatgcaaa aggcgacggc ttctctagtc attgtggata agattggtgg tcaggaaatt
     4021 gaaaagcttg gggataagat caaggaagtg agtgaccaga ttgagcagat tttggggctc
     4081 aatgctgagc agttcaaaca gattattctc cttccacaaa atgatttcag ccgtttcttg
     4141 aaagaagatt ctaagaccaa gactcaaatt ttaaagaaaa tctttggaac gggtattttt
     4201 gaccattttc aaaagagctt ggaagagcgt cttcgtcaga gtaataagga tatggaaaag
     4261 cgtcaggctc agctagatgg tcattttgcc agtcaggttt ggtctgagga agaattatcc
     4321 gtcttggagc aaacgccagc ctctgaaaaa ttgacacgtc ttgaagagtt tttgtctcag
     4381 cgtcaagaaa atgttacgaa gcaaaaaagt atcttgaagg ctgcccacga ggatttggca
     4441 caactgcaga agagcttgca aactgcccaa gatttggcaa agatttttca agaattggag
     4501 caagccaagg aacgttaccg tctggaaatt gaggaggggg ctcaaggaca ggcagaggca
     4561 aaagtgcatc tggaggaatt acagtttgct caaggtctgc aggaaaccat tcggaccttg
     4621 aagcagtatc ggaaacagtt gatgcaatta gagcaggacc ttgaaattgc tcaagaagcc
     4681 ttaagtgaaa agcaacaggc gtttgaggat gttaaggcta aaaaagagga actcacagtt
     4741 caatctaagg attttcttca aaaagaagag gagcttgaaa cttggaaaga gaatattatc
     4801 tatgcccaga gtcttgccca agaacaggag aaaatcaaac gttcaacgac taactacaag
     4861 cagttggaag agacctatca gcaggctaga aaagaggttg agatgcttaa caagtccttg
     4921 tctgacttgg aggctaatcg tcttagttta gatagtttac atgaggccga aaaactcttc
     4981 cagattgtgg gctacagtgt ggagaatcaa cttgctcagg acctgaaaga aatagagaac
     5041 ttgaatcagg agttgacaaa gaccgaaaaa cgtcatcaaa cgttatcttt tgatattgat
     5101 caagctcaag aaattctcaa agaattggaa gaggagttaa gaaggacttt ggtttcacgc
     5161 cgtcaactca ttattgtcca actgcaggca gagttagagg aggggcatcc ttgtatggtt
     5221 tgtggtgctc tggaacaccc taatgttggt ggagcacagg ctgatgaagt ggccttgaaa
     5281 aatctcatgg atcaggtgga gaagcttcaa gctcaaaaag aaaagcaagt cgctacttta
     5341 tcaaatcgtc aggctacctt gagtgaagtt gcatctaaac gtcaggattt gcttgaccaa
     5401 gtggctaaag tcaaggcaac tcttgaaaag cactatcaag aattagaaga gcacgttaag
     5461 ggacggtttg attttgattt ttcgatagac tatgaaactg accgtgggca agccctactc
     5521 ctgaaggttg agcagtatta tcaagagtta caaaaacgtt atgataagga agagacagat
     5581 tatatccgat atcaagatga gctaggtaag gctcaaaaaa aagcgacaga tttggctaaa
     5641 acctatcaag aggccaaggc agtgcttgac caagctcaag aacgcctaga ggacctgcag
     5701 gaagctcatc cagaacttga gtctgttgag gtatatcaag aacggatttc ccttgctcat
     5761 caggagctga acctctacaa taagcaagtc aaggaaaata gcgaagccta caaccaactt
     5821 catgccgaca ttaaaggaat aaaggggcag attgagagta taactaagtc taaagataag
     5881 gtaaatcaag atgttaagcg attatctgct gaattagagc aaagtctcaa ggctgaagga
     5941 gccctcgcta atgacttaga gcaggtcgaa ctctggctta ttgaggtaaa taatcaagct
     6001 attcctatgc ttcaggccaa attaacgacc tatgcaacgc tcaaacaaga attacaggcg
     6061 cagattcata aggggcaaga gcttctccaa aatcaagaac aaccagatct cgatagtcta
     6121 gcgcaagcag tacagaattg tcaggaaatc tatgataggc agctcgctca gttttctgtc
     6181 atggaaaagg gacttaagga tgcgacggct acctaccaag cggctaaaac ccttcaagac
     6241 agtaaccaag aggcctttaa ggcccaccaa gaactcagtg atttggttaa ggtggttaag
     6301 ggagaaaata ctgctctaac tggtcgtctt aatcttgagg tctacgttat ccgtcagtat
     6361 ttccaacaaa tcttggacta tgccaatgct aactacatcg gactattaac ggataaccgc
     6421 tattcctttg ttctaagtga ggaaggacgc agggcgcgtg atcacttcgg tttggatatc
     6481 aacgtctatg accagctgac aggtagtgaa cgctccgtta aatccttgtc tggtggtgaa
     6541 acctttatcg ctgcactggc cattgcccta tccctctcag aagttgtcca aaataccagc
     6601 aagggtgccg ttgttgaagc tctcttcatc gatgaagggt ttggctcact ggataaggaa
     6661 gccctgacca aggccatttc tgttctggaa caaatcggtg aaaaccgcat ggtcggtgtc
     6721 atcagccacg tagacgatat gaaagaaggt attgctcagc aactagttat catcaagtcg
     6781 cacgatggca gtagccgtat taaaattgtg gataaggggt aggaggaatc agtttatata
     6841 atactctata tcagataatc gcagttgtag ccatgtcaaa tttgttctaa tcagcataga
     6901 aaaaaggtag ttgcatcaac aactacctta tgtagaattg ttaaaaagct gatggtttgt
     6961 ataacatatt taattcgtcc tactcgtaaa aaagtgcgga cggatttttt tgtcatcata
     7021 tttgacaatg ttatagcaaa aactaatcaa agtaatatga ggctacctaa tgtctcccta
     7081 attcgttgaa cttttagcta ggtgaagtaa ttatcaattt cctcctcatt ttttagtata
     7141 tccacctcat caacaccaca acttactgct aattctattg gtcaacattc tactgccaaa
     7201 caaagtcgaa aagaaatcga attggctgca gctaaacttg tagaggacaa acaagcagaa
     7261 gataaagcaa gtattttatc atcagatact gtaaaagaat ttttgacaca gtactatacg
     7321 aaagaaaaac taggggaaaa taatacacgt attcaacctt atatgactga atcggcctat
     7381 tctcaagaat tgacaagtca aaatgatgcc atgaaccaag tgtataagga ctatattttg
     7441 gattatcatt ttgaaaaagc agatatcttt gtcaatcaga ctacgaatca agccattgcc
     7501 atggtctctt ataatgtaac ttatgtatct gatttaaaga atgccaacca atcaaagaca
     7561 aaccaaacag aaaccagaac ggttaatttg aactattcga aactacctgg taagttattg
     7621 gtcaaccaag tacaggtttg gaaatctggg ttagatgatc tagataaggc aactcctaaa
     7681 actttagaag aatcctcatc tgttccatca ttgccgaata ctacgacaaa atgatgatat
     7741 tttatgaata tagaggaatg taagcaaatt tcaattcttg atgtagccaa tcgattaggt
     7801 atctccttta aacaagttta tgataaagca gtttactgga tctatagtgg tgttaaagga
     7861 caatatgaat attagaagga gaaaaaatga ctaaacatag ttatgttgcg aaatttaagc
     7921 gtaaagacga aaccgtcttt acgaaaaggt ttctagcttc agatttattt gaggctgttg
     7981 aacatgcgct agagtatgcc actaagcgag atattctcta tctcgactta gggcatgcag
     8041 gatagtagtc agtagaaagt agaggctggg acaaaaagtt ctcagtcaca aaaaagctag
     8101 agatttccaa ttgtggaact ctagcttttt aaattcgagt cactctcttg ttatatttca
     8161 gaagattttt ggtcaattct atttcaccaa gtctatcaca atcatgcaaa aagcaacggt
     8221 tttatgaact gcaccccaaa agttagacag aaaaaatcta actttcgggg tgtttttatt
     8281 atgaaattga cttatgaaga taaggttcaa atctatgaac ttagaaacca aggatatagc
     8341 ttagatcagc tttcaaataa atttgggata aacatttcta atcttagcta catgattaaa
     8401 ttgattgatc gatacggaat agaaatcgct aaaaaaggaa agaatcgtta ctactctcct
     8461 gaattaaaac aagaaatgat tgataaagtc ctatataaag gctattctca agatagagtt
     8521 tctcttgaat atgctctccc aaatcgtggg acgcttccta actggctcgc acactataag
     8581 aaaaacgggt atactattgt tgagaaaaca agaggaaggt tatctaaaat gggacgtaag
     8641 ccaaagaaaa aactggaaga aatggaacgt cttcaagcag aaaatgagta ccttagagcg
     8701 gagaatgcag ttcttaaaaa gttgagagaa ctccgattga gggaagaaaa agagcaagaa
     8761 gaaaaacgga aattgtccga ggattggtaa ctgagttttc tttagatatg cttctaaaga
     8821 ttattaagct tgctcgttca acctattatt accacttaaa acagctggat caaaatgata
     8881 aggattatga cattaaagct gaaattcaag ccatttttac tgagcataaa ggaaattacg
     8941 gctatcgtcg aatgactctt gaattgagaa atcgaggaat tgtgattaat cataagagag
     9001 ttcaacgtct tatgaaagta cttggtttaa ccgctagaat tcgccgtaaa cgtaagtatt
     9061 cttcatatca aggagaggtt ggtatgaaag cagagaatct catccaacgc cagttcgaag
     9121 catccaaacc attggaaaaa tgctacacag atgtaacaga atttgccatt ccagcaagca
     9181 gccaaaaact ctatttgtcg ccaattttag atggcttcaa tagtgaaatt atcgcctaca
     9241 atctttctaa gtcaccgaac ttgatacaag tgaaagctat gttagaacaa gcctttacag
     9301 agaaacatta caaaaataca attctccata gtgaccaggg atggcaatat caacatgatt
     9361 tctatcatca ttttttagag gagaaaggaa tccaaccatc catgtcacgt aaaggcaata
     9421 gtccagacaa cggcatgatg gaatccttct ttggcattct taagtctgag atgttttatg
     9481 gttatgagaa gacgtttaag tcaattgagc atttggaaca agcaattgca gactatatta
     9541 attattacaa caacaaacgc attaaggtaa aactaaaagg actcagtcct gtacaataca
     9601 gaactaaatc ctttacttaa attatttgtc taactttttg gggtcagtac attatgccgt
     9661 tgctttttgg agctaaagga cttttgtccc agactcttta tcccacgacg ataacgataa
     9721 tgccttcaaa tacgacaaga agaagtgtta gtaaaatttg ctttttcatg tgataatcct
     9781 cacttttgtt tttctttatt gtatgatatg atgaaagcaa atgaaaatta ttcccatata
     9841 tgcgtgatgg aggtgtagta tgaaaaaatt tggagaaatt tttaaaaagt ttcgagaatc
     9901 gagaggatta cgattaaaag acgtcgcaaa ggctggtata tcaacgtctc agctctctcg
     9961 atttgagaaa ggagaaacag atttaacgat ttcaaagttc atgtttattt tagatgaaat
    10021 caatatgcca atagatgaat ttatgtatgc ggtccatgat tttcatagag atgagttaaa
    10081 cgaactgtta tcgaaagtac gtcattttgt gtcaacacgt gacgtagaag gtatgaaaaa
    10141 attactttat tctcagatgg aactggaaga taggcgagaa aaatttcatc aaatcaatat
    10201 tattttattg aaaattcgtc tacaggattt atcaggagaa acttactata caaaggatga
    10261 tttgacatat ttaacagatt atctctttag tgtagaatac tgggggtact atgagttatt
    10321 gattttctcg aatactttag atgtattaaa tcatgatgtt ttcatggtct tagcaagaga
    10381 aatgtttagg cgttctgatt tttacaaaga aattccaaat aacagacgat taatttcaac
    10441 gatgctttta aatggatata ttacatgtgt tgaaagagaa aaatttatgg atgctttata
    10501 ttttgaaaag cagctaaatc aatgcttttt tattgagaca gaagtatatg aacgtttagt
    10561 ctttaagtat gcacaaaatc tttatcaata taaagaggat ggaaatgtga aagcaattat
    10621 tgaaatgaag aagtgtgttg gagcgatgaa attagcagga agtcatcact tagcaaagac
    10681 ttatgaagga catttagaaa aaattttagc tagtagttag aaaatgcaaa tatgggaata
    10741 ttttattgta agtgttgaaa agaaatataa tcacagtatc atattcgaaa ggagtaccaa
    10801 atatgtctaa agagcttgaa aaagtccttg agtctagttc aatggcaaaa ggtgacggct
    10861 ggaaggtgat ggcaaaaggt gacggctggg agtgataaag taatttatcc cataagttaa
    10921 gcagaggcta tattttcctc tgctttttta gaaaggtatt caatatgatg acaatttcag
    10981 aagatttttt atttagacta gaaaagtttg gtggaatttt gataaataaa gtaacttttg
    11041 accgaattga gttagatgag agtgaagctt attttcttta tttggttcaa aatcatggtt
    11101 ttgaaattgc tacgtccttt tttaagaaag aaataaaagc agggaaacta gagcgagtac
    11161 tcttattaaa tatctattct gataataata ttgagggatc atcgaaaaat cctgacgaga
    11221 ctcttcaaaa tgcgagaaag catgtagcaa aattaaaaaa acataacata ttgagttttc
    11281 cgcttgaact agtaatatac cccagtatgt actgtgattt aaaatgtggt ttttgttttt
    11341 tagcaaatcg tgaagataga aatgccaaac ctgctaaaga ttgggaaaga attttgcgcc
    11401 aagcaaaaga taatggagtg ttaagtgttt caattttagg aggggaaccg actagatatt
    11461 ttgatattga taatttgttg atagcttgtg aagaactgaa gataaagact actataacaa
    11521 ctaatgccca attaataaag aaaagtacag tggaaattct agctaaatct aaatatatta
    11581 caccggtttt atctttgcag actttagatc ctaaattaaa ttttgaatta atgggggtga
    11641 gacctgatag acaaattaaa ttagcgaagt actttaaaga ggttggaaaa aaatgtagaa
    11701 ttaatgcagt gtatacaaag caaagctatg agcagattat agaattggtt gatttttgta
    11761 tagagaataa aatagataga ttttcagtag ctaattattc tgaggtaaca ggatatacga
    11821 aaataaagaa aaaatacgat ttagctgatt tgagaaggtt gaatgagtat gttacagatt
    11881 atataactca acgggaagct aatttaaatt ttgctactga gggatgtcat cttttcaccg
    11941 cttatccgga gttgataaat aattcaattg aattttcaga gtttggcgaa atgtattatg
    12001 gatgtcgtgc aaaatatact aagatggaaa taatgtctaa tggggatatc ttgccttgca
    12061 ttgctttttt aggagttaat caaactaagc agaatgtctt tgaaaaagat ttgttagatg
    12121 tttggtatga tgatccgttg tatggaggga ttcgttcttt tagaacgaag aattctaagt
    12181 gtttatcttg tggattgtta aaaatttgcg agggtggctg ctatgttaac ttgattaagg
    12241 agaagagtcc aaaatatttt agagacccag tttgtaactt atgagtaaga agatttttaa
    12301 tttatacgga atgaatatgt ttctatctgg attaccgtac tactttgtag gaattttact
    12361 attaaagcac ttaggttttt cgttcacaga aatagctact ttatcagtta ttactgagct
    12421 atgtggctca gtttttgata ttcctttaag ttatatttca agtaagattg gttacaagaa
    12481 aattttggct atttcaaatt tattattaat tttagcatta tggggcctat tgtttggaaa
    12541 atcaaatata atatatattt cagcgatatt ttttggattg tcagaatcat tatcttcagg
    12601 agttcttatt tcttataatt ttgaaataat tgatgacgaa gttgtatata aatcattttt
    12661 gaaaaatctc aacacattaa aatatatttt tattgctatt attacgatta tatctccacc
    12721 tttattgcat aggaattata tttatcctat tattatatcc attgtatttg taattttcag
    12781 tttattatat ttaataggat tacccgagat taaaaaggaa caaaataata aacaaaaatt
    12841 ttttagcctc gataatattc aaaatattcc atggttatta ataatattag gagtagcatt
    12901 ctcaactcta attatgatta gcaattctta tgcagggata ttcttaaatg aacagggact
    12961 ttcactagat atgctgggaa ttatactatt tatgtttaat atatctatgg ctttggggag
    13021 ttatctaaaa attaagtttg aagtaagctt gatgttacca gtattagcta tactcatgtt
    13081 ttttcaaact aatctaatca tccaaattat aatcctttta ttaatgcgtg ttcttaattc
    13141 caactacaat aatcattttt attataaatt taatatgtca atagaaaaaa atagagcagt
    13201 atcatggtca gtatataatt tgtttatttc gattagtttt atgttagctg atttcctagc
    13261 tggtattttt gctgataact ttagtattag gagcaattat ttaatatttg gtatagtagc
    13321 tctttgttgc ttagtatctt attcattttc taacagagag aaaagaactt aaaagttgta
    13381 tttctaattc atttgccaaa ttattgatag cacaattgtt tgcaaattta gcagatattt
    13441 tctttagagt ataagattga atgatatgct tggtattgag tatatgtcag ttatggttat
    13501 ttgtcctact ggtagggcta atgacggtag tattttagca gataaaaaac aatggtatcc
    13561 tgtttttctt gatttaacag agcggatttc taaaggagag ttcaaagtta aatttaaaat
    13621 tgttcctcct aatgaaagtg atgttttttt gacacattat tttccgcttg cattttataa
    13681 tagatcagat ttattagaaa atgtttggca tcaaaaagta gatataaatt ttgataagcc
    13741 aagggaaata tcttgtcaag ctggagttag agcatgttca attaatcata aaggagatgt
    13801 atacgggtgt gacttgatga atggtataga tgaattagtt gctggaaatg ttaaagaaca
    13861 aaagtttagc gaaatttggc accattctgc tgtatttaat aaactaagat caattacatt
    13921 tgatgatatt tctgggaaat gttcagaatg tcccctacca tggtgtggtg ggggatgtcg
    13981 atgcagtgcc ttggaattag atggaacgtt actgggctct gatttagcct gcttttatga
    14041 acaaaaagga ggtggagtag tcgtatgaaa gaacattttg tgataagagg taagagagat
    14101 ttcattgtaa ataaagtagc agatgaatac ataggatacg atctacttga ttagagtact
    14161 attcatttga tgaaatagga gcagaaatac tttattgcat ttctaaaaat ttttctttag
    14221 acaagattgt agaactatta cagcaagatt atgaggtatc tgctaatgat tgtaagcagg
    14281 caattatttc atttttagaa gaaactccta ttttgcatat tatttatgca aatttagtta
    14341 aatctgatct ttacttacat ttgaagcctt ttagagagga aaaatgatag attcaaaaga
    14401 aattaacaaa tttgcctttc ccttagtttt aacaaatatt ggtcaagtaa ttattgggca
    14461 gatagcattg cattttgctg tgaacaattc ctcaattgct ctgtcaggaa tttccattat
    14521 tcagaatctc ttatttgctt ttggtggact tttaggagca ttcagtttgt catttaatat
    14581 taaaagctct aaggcgtact ctaatcggca aactaacagg tttgatgatt tattgaaatc
    14641 aaatctaacc ttagatttaa ttatcggagt tgcctttgcg gtttttgtca ttatttttgg
    14701 aaatgtaatc ttgaagcagc tctatggatt taaagggcaa ctattgtcct tatccaccat
    14761 ttatttagtc ttcatgtctc catatatcgg attgacatta ttaaactttt cgctgacaaa
    14821 tttattaaga gttcaaaaga aaacaaaacc aattatgtgg gttggactta tcagttcatt
    14881 aatagatgtt gtgttaaatt atgtactggt accacaaatc ggaattaagg gagcagccat
    14941 atcaacgatt gtatccttag ctttcatatc gcttagttac ttgtttatgg tttatccaat
    15001 gattttgaag gctttatcca ttacatctac aactaaattt gaattaataa catttggtat
    15061 tcctttggtt ggtcaagaaa ttctggagag tgttttgttt attatggtgt ttgatgcctt
    15121 gatgtcgaga ttaggagtag aattgttggc tatttatgca gttattagtc aattgctttc
    15181 aattgtgagt gtaccttctt ttgtttattc gacaaccgtt tctatctatt tacctgaagc
    15241 agagaaaata ggagaggtta acgtattttt aaaaaacata tttaaaaatt cataagatcc
    15301 ctgaaaagcg atattatagt caggagaaaa tgccttccct aaaagtttat agtaattctt
    15361 aatctctctg aagttgatga ttatataatt caaattaatt atctaaaaaa tagttatatt
    15421 cttgtatctc tttgaaataa tctgctatca gtaatttctc tttcattgtg agattatctt
    15481 tagcgatttc atataggaaa gttcctatat tatttccaat aacggatcct aaaataggta
    15541 ttggaattac agcatgtcct aatattgagg ataatgcact aactgatact tcaacacata
    15601 atatttgcga atttagtaaa aattcttctt ttgtgattaa gtttttacgg aatttgtatg
    15661 cttctttagc gataccaaat gaagcagtgc acaatgaact tgctactgct gcaggagtag
    15721 ctgtgtaatt cgttagggcg tatatcgtaa tgcctcgagt acttcctttt atagctccaa
    15781 ttccactatc tttagaaatt tcaagacaat cgtcttttgt aaactcacta atagttttcc
    15841 ctaagcgctt tttttaatta ttgctgttat aaatgcagta ccccccttct agagaagctg
    15901 ctatagcgga tatataggct ccctgtttta aagtaggttt gcttttatcg tacatatctc
    15961 ttataatgct agtatcaata tcctttatat tacctttttc attataaata gtggtattga
    16021 tttgattcct ttgtacctcc ctataactaa ctttcgaagg ctctatatca gaaagtttga
    16081 tgctttctgt ttcgaagaat tgatttactt ctttccattg cactcatggt agatatctcg
    16141 aatagtatta agaatagctt tcttttgacg atgatagtta gtccttgtct ttttaagata
    16201 attataataa gcattgggat gaatattcat atgcaagaac aaccaacgca aaccaaaatc
    16261 ttctttatag ttatcaataa aacgatatgc ctctaatcga tttcctttgc aaagaatgcc
    16321 gctgcttttt ttaagaaatc attttccttt tcaagctctg ccttttcttg acgtaattta
    16381 cgaacctcct ccatgagttc aagctgtgat ttttctttat tattagtttg gcattctttg
    16441 cgataatgtc ttacccaatt agagattgag gcttgggata cgccatattc agcagctaag
    16501 ctttttaatg ttcatccgtc ttgaatgtgc agtcgaacaa ttttttatcg tgtttcgtct
    16561 ggatagtgtt tcatgttatg tctcctattc taatgaatag tttaacttat taggtaggag
    16621 tgttacaaat ttactatacc agaacagtct agtttactat ataagtctct aaatcgttct
    16681 aaatgtttaa tatacaaatc taattgttct ggttttaacc atattttcgt tggcataatt
    16741 ttttctcttt tcctaataaa taaaaaagat agcacaaata tttccttgtg ctatctcaac
    16801 atttagttaa taaaatattc cttagtcata attatatttt tgctgatttt tagtcataaa
    16861 ttaaattact tctccaggat tgtcatttta ccgtcaat
//
