LOCUS       gnlProkkaPFEKKOIM_45   14712 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|PFEKKOIM_45.
ACCESSION   gnlProkkaPFEKKOIM_45
VERSION     gnlProkkaPFEKKOIM_45
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:34:30
            Original ID  :: gnl|Prokka|PFEKKOIM_45
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 49891
            Orig. end    :: 64603
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14712
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[5000:13345]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      5001..13345
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..14712
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14712
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             14..712
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1156:Chloramphenicol acetyltransferase (Score: 59.8;
                     E-value: 4.6e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_57"
                     /transl_table=11
                     /translation="MTAQKMSAQEIIAFIGNAEKKTNVKVTFEGELATAVPSSVTKLGN
                     VLFGDWKDIEPLLANLTENKDYVVEQDGRNSAVPLLDKRHLNARIEPGAIIRDQVTIED
                     NAVVMMGAVINIGAEIGAGTMIDMGAILGGRATVGKNSHIGAGAVLAGVIEPASAEPVR
                     IGDNVLVGANAVVIEGVQVGNGSVVAAGAIVTQDVPENVVVAGVPARIIKEIDEKTQQK
                     TALEDALRNL"
     CDS             791..1924
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1244:amidohydrolase (Score: 326.9; E-value: 2.3e-99)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_58"
                     /transl_table=11
                     /translation="MTLDLIKIRRDLHQIPEIGLEEFKTQAYLLERISEMTEGKDFVEQ
                     RTWRTGILVFLHGSAPEKTIGWRTDIDGLPIVEETGLDFKSIHEGRMHACGHDIHMTTA
                     LGLLDQMLQVQPKNNMLFLFQPAEENEAGGMLMYEDGAFGDWLPDEFYGLHVRPDFKVG
                     DIATNTNTLFAGTCEVLVTFKGKGGHAAFPHEANDALVAASYFITQVQTIVSRNVDPIQ
                     GGVVTFGSFHAGTTNNVIAETAEVYGTIRTLTQEMSLLIQKRVRQIAEGVAASFGMEVD
                     IMLKQGGYLPVENNPALAKELMAFFDASPMVNLIDCLPAMTGEDFGYLLSKVPGVMFWL
                     GIDTPYALHHPKMSPNEEALAFAVSEIGKFLKYKAED"
     CDS             1993..2520
                     /locus_tag="ctg19_59"
                     /transl_table=11
                     /translation="MKNKLRKTVLSQLTSQEPETKAEIDKNLLEKLIALPAYKDAQVIA
                     TYLAFPHEYDTSLLIKQALKDGKRLLIPKTYKQGQMIFVDYDPDNLVATSFGLMEPASD
                     LAVEKSEIDLIHVPGVVFNAEGYRIGYGAGYYDRYLSDFEGETVSTVYPCQEMDFIPYS
                     HDIAVREIITCK"
     CDS             2511..3185
                     /locus_tag="ctg19_60"
                     /transl_table=11
                     /translation="MQVNEWKKYPATYLLLGLTTLTFICQYLLNSFQATSPLSLFKMGA
                     MFGTFVQYNPLELWRLITPIFVHIGVEHFLFNMLTLYFMGRMAEQIFGTLRFLGLYLLA
                     GVMGNAFTLFFTPNVIAAGASTSLFGLFSAIVILGYYSHSPLLNQLGRNYLALIVINLI
                     FNLFTPSVGITGHLGGLVGGALAAIFLANKVESRLFSKGWRFTSFLTYVTLLLIVLGFT
                     YL"
     CDS             3285..3971
                     /gene_functions="other (smcogs) SMCOG1164:transposase
                     IS3/IS911 family protein (Score: 25.1; E-value: 2.3e-07)"
                     /gene_kind="other"
                     /locus_tag="ctg19_61"
                     /transl_table=11
                     /translation="MSKRSPKSVSEKLEIVLLHLEEGKSLSWLTRNQGISKDTLSNWVR
                     KYKEAGVDGLEESRQWKKYSKELKEQAVSDYLNGLGSLKDLTKKYGISDPYVLRSWIKS
                     YTSGKELKATSKGMRRMKQGRKTTFEERIEIVNFTLAHEKDYQGAVEKYGVSYQQIYSW
                     VRKFEKDGSNGLLDRRGKGLTSKPNLTPEEELRLKIKQQEERIKYLEMENGLLKKLEEI
                     KRRNRR"
     CDS             3986..4855
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 247.8; E-value: 1.9e-75)"
                     /gene_kind="other"
                     /locus_tag="ctg19_62"
                     /transl_table=11
                     /translation="METFQAIKEYADEYEEVSISHLCHILKVSRSGYYKWLQHQETTSE
                     QENLGLMDIIKKLHSQHNGILGYRRMTLFVNRKLETNYNKKRIRRLMHILGLRSIIRRA
                     KGYCTKTSFVNVEDNILNRNFTATAPNQKWCTDVTFLKYGFSCKAYLSAIKDLYDGSIV
                     AYVVGQFNDNELVLETLRKAQKANPNATPLIHSDRGSQYTSKDYYRLTTQYQMTRSMSR
                     VGKCIDNAPIESFFGHFKTECYDLKKYKTFEELVSDIDAYIYFYNHQRFQERNNGLAPL
                     EMRNKAVA"
     CDS             complement(5001..5255)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_63"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.5e-14,
                     bitscore: 46.4, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENLNTLDLETLASVEGGGCSWGGAGGATVQGAIGGAIGG
                     AFGGNVVLPVVGSVPGYLAGGVLGGAGGTVAYGATCWWS"
     CDS             complement(5506..5907)
                     /locus_tag="ctg19_64"
                     /transl_table=11
                     /translation="MKLKNISSSVLRSFRTITAALAVFLISISLSLYKSKISPGTWLTV
                     GALAFVVIFVNGLLYRMLKKRPDSVNLLTIRQSFIVFPVITFLVLSVEFYTLLTFSDTT
                     DRIVLAVLMLLLILCDFLSYLQVKKYFKQ"
     CDS             complement(6237..6404)
                     /locus_tag="ctg19_65"
                     /transl_table=11
                     /translation="MFKNSKPYLLATILIVMGLANLFRSLDAVHHTINLLGLTVLLYSL
                     LFKKWVQFQK"
     CDS             complement(6762..6905)
                     /locus_tag="ctg19_66"
                     /transl_table=11
                     /translation="MFDLKSYILGMVSMAVMSFLDKPIMSFLEKHKATNSVKKKSSVKK
                     KS"
     CDS             complement(6912..7142)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_67"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.1e-19,
                     bitscore: 60.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGVCSWGGFAKQGVATGVGNGLRL
                     GIKTRTWQGAVAGAAGGAIVGGVGYGATCWW"
     CDS             complement(7498..7698)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_68"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.6e-09,
                     bitscore: 28.2, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNNKQLERFKKLDTNALSNVSGQGYGAQCVIGTTGMTIVGAAFFG
                     IAGAGAGFAGGSTAFCYDTAK"
     CDS             complement(7717..7893)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_69"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.1e-11,
                     bitscore: 37.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MATQTIENFNTLDLETLASVEGGLSCDEGMLAVGGLGAVGGPWGA
                     VGGVLVGAALYCF"
     CDS             8144..8881
                     /locus_tag="ctg19_70"
                     /transl_table=11
                     /translation="MKIYLLEDNSIQMGRLEDAVAHELMTFGKDLSCVQSFDKPDQLLS
                     AITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNNPYAIIAFVTTHIEFMPQAFGVTAY
                     KYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLSTSDI
                     KHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNLTNYEATLINGQ
                     VLPVSRMKIGKIAQIVEERGRGC"
     CDS             8875..10215
                     /locus_tag="ctg19_71"
                     /transl_table=11
                     /translation="MLTTLWLLFLTLLSAGLEIILFLYLMGQKIRLRYFFLLLIFNLAF
                     NFIYNHSSWFIIKFWGEDIYYLLLSFLLSTKTKKPLKIKIFNGLFPDILNNLSLRLITF
                     FIFPFFNISITDYQSSLLISIPSSIAPLCLSFLFIKLFKGSFTILQKQKSNSPIQHIII
                     VANFFMFGYTLLLQILMYLENTTHSSTLELRKLCVVISLVLFFIMIVFLDRNIREMIQG
                     QLDFQKNLQLENLYTYNKHIEGLYNSVRSFRHDYSNLLVTLRLGIDKDDMDIVKEAYDS
                     VLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGME
                     TLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHCSQLLSISNTISEEKTETKTIFER
                     GVSNKGRERGIGLANVTEILDNYINVNLETQSNNFSFTQQLTITKKA"
     CDS             complement(10233..10394)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_72"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.2e-08,
                     bitscore: 27.5, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MANNTINNFETLDNHALEQVVGGSGWMDYINGFLKGFGGQRTLPT
                     KDYNIPQA"
     CDS             complement(10409..11776)
                     /locus_tag="ctg19_73"
                     /transl_table=11
                     /translation="MNPQLFKSTEFYHRRYHNMSTVLITPLILLVIFLFLFAFFAKKEV
                     TVTSRGSIEPTKVIAVIQSTSDNTIIDNQLVANKVVKKGDTLVQYSETMEASQKEGLQK
                     QLELLKRQESGLKTLQSSLTQGTNLFQEQEDEFGYQSTFNTYLSQAQDIDLGVAKTNTE
                     VNNQAAIASNTGSAIDNQISQLQTQVSEYEALSQAITNHETTLPEGNPHQATLNAYNSQ
                     YATTPDASVTDQYLSQVNTNISSLNASIGNLEIQKAGTGTVVTYDNSDSTKKEALKNQF
                     LQNAGQQLSSVETQINDTESKINQADVLLTNTLIQSPEDGILHLSQADKKATMAATGTE
                     LAQLYPDMTQTQEVAITYYVNSDYVPKLQKGQSVRLTLDKVGNHGTTIIGKLESIDNSA
                     TETERGNVFRVTARASISEKEAQNLRYGLEGRVTSVIDQKTYFNYFKDKLLNLQDQ"
     CDS             complement(11792..13345)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 295.4; E-value:
                     1.5e-89)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg19_74"
                     /sec_met_domain="TIGR01193 (E-value: 1.6e-245, bitscore:
                     809.1, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKSTLGIISIGLVVTYVLQQMMTFARDYLLTILSQRLTIDVILSY
                     IRHIFELPMSFFATRRTGEVISRFSDANSIIDALASTILSLFLDFSIVIIVGGVLLIQN
                     SNLFKLVLCSVPIYTLIVFAFMKPFERMNHDVMQSNAMVNSAIIEDINGIETIKSLTSE
                     KVCYQKIDGEFIDYLDNSFRLSKLSILQTSLKQGAQLILNVLILWTGAQLVMGNTISIG
                     QLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYLIESEFGQSDDTYQEGIAD
                     GDITVTDLSYKYGFGRDTLTDVCLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGH
                     IDFNGQNISRIDKKTLRQHINYLPQQSYIFSGSVLENLTLGAARGITQADILKACEIAE
                     IRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKQ
                     VIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDHGRVVETGSHQDLMSYPGFYYQLFRK
                     "
     CDS             complement(13342..13959)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg19_75"
                     /sec_met_domain="Peptidase_C39 (E-value: 2.9e-46, bitscore:
                     148.9, seeds: 36, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKGFGMFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRE
                     LAKTNKEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDVPYPFIAHVNKDGKLQHYYV
                     IYKSTKDYLIIGDPDPSVKVTKMTKERFEKEWTGVTLFMGPEPSYKPHKDKKNGLWDFL
                     PLIFKQRSLIANIVFASLLVTLINILGSYYLQGILDEYVLIK"
     CDS             complement(14541..14711)
                     /locus_tag="ctg19_76"
                     /transl_table=11
                     /translation="MRNKSVIVELQNITRKRFIPMTQFTTELLNFGSIISVVGKTTVEI
                     IELFEMVPPQG"
ORIGIN
        1 aatggagaat ctcatgactg cacaaaaaat gtctgcacaa gaaattattg cttttatcgg
       61 taatgcagaa aagaaaacaa atgttaaagt aacttttgaa ggggaattgg caactgctgt
      121 tccaagttct gtcactaagc ttggtaatgt tcttttcggt gactggaaag atatcgagcc
      181 acttcttgca aatttgacgg aaaataagga ttatgttgtg gaacaagatg gccgcaactc
      241 agctgttcca ttgcttgata agcgtcacct taatgcccgt atcgagccag gtgccattat
      301 acgtgaccaa gtaacgattg aagacaatgc cgtcgttatg atgggggctg taatcaatat
      361 cggagcggaa atcggtgcag gtactatgat tgatatgggt gctatccttg gtggtcgtgc
      421 tactgttggt aaaaacagcc acattggtgc gggtgcagtc cttgctggcg tgattgaacc
      481 agcttcagca gagccagtac gtatcggtga taacgtgctt gttggtgcta atgctgttgt
      541 gattgaaggt gttcaagtag gtaacggttc agtcgttgcc gctggcgcta tcgttactca
      601 agatgtccct gaaaatgtgg ttgtagcagg tgttccagct cgcatcatca aggaaatcga
      661 tgaaaaaaca caacaaaaaa cagcactcga agacgctttg cgtaacttgt aatatattga
      721 tagtagaggc ccgtaaggcc tctatttcta gattctctat aaaataaata taaataaaaa
      781 ggacaaaaac atgacacttg atttaatcaa aatcagacga gaccttcacc aaattcccga
      841 aattggtttg gaagaattta aaacgcaagc ttatctctta gagcgtattt ctgaaatgac
      901 tgaaggtaag gactttgtgg agcaacgtac ttggcgtaca ggaatccttg tttttcttca
      961 tggttctgcg cctgagaaaa ctattggttg gcgtacagat attgatggtc taccaattgt
     1021 agaggaaaca ggtcttgact ttaaatctat tcatgaaggt cgtatgcatg cttgtggtca
     1081 cgatattcat atgacaacag cgcttggtct cttggaccag atgcttcaag tacagcctaa
     1141 aaataacatg ctcttccttt tccagccagc tgaagaaaat gaagctggtg gtatgcttat
     1201 gtatgaggat ggtgcctttg gagattggtt gccagatgag ttctatgggc tccacgtccg
     1261 tccagatttt aaggtaggag atattgctac aaatacgaat accctttttg caggaacttg
     1321 tgaagtactc gttactttca aaggtaaggg aggtcatgcc gcctttccac acgaggccaa
     1381 tgacgctctt gtagcagctt cttactttat tacacaggta caaactattg ttagtcgtaa
     1441 tgttgatcct atccaaggcg gcgtagttac ctttggttct ttccatgcag gaacgaccaa
     1501 caatgttatc gctgaaacag cagaggtcta tggtactatt cgtactctta ctcaggaaat
     1561 gagtctcctc atccagaagc gcgtgcgcca gattgcagaa ggcgtagcag ctagcttcgg
     1621 tatggaagtg gatatcatgt tgaaacaagg tggttatctc cctgtggaaa ataatccagc
     1681 cttggctaaa gagttgatgg ccttctttga tgctagtcca atggtgaact tgattgattg
     1741 tttgccagct atgacgggcg aggattttgg ttatttgctt agtaaggttc ctggtgtcat
     1801 gttctggttg gggattgata cgccatatgc acttcaccat cctaagatga gtccaaacga
     1861 agaagctctg gcttttgcag tgagtgaaat tggtaagttc cttaaataca aggcagagga
     1921 ctaatgatag ttgataaagc taaaaaaact accaaatctg atttttggta gcttttttga
     1981 tatgataaac ctatgaaaaa taaacttaga aaaacggtct tgtctcagtt gacttcacaa
     2041 gaacctgaga ctaaggctga gatagataaa aatcttttgg agaaattgat tgccttacct
     2101 gcttataaag atgcccaggt gattgcgacc tatctggctt ttccgcatga atatgatacc
     2161 agtctcttaa tcaagcaggc cttaaaggat ggtaagcgtc ttttgattcc caaaacctat
     2221 aaacaaggtc aaatgatttt tgtggattac gatccagata atcttgttgc aacctctttc
     2281 ggcttgatgg aacctgcctc tgatttggca gtggaaaaat cagagattga tttgattcat
     2341 gtgccgggag tagttttcaa tgctgaaggt tatcgtattg gttacggagc aggttactat
     2401 gatcgctatt tgtctgattt tgagggggag acagttagca cggtttatcc ctgtcaggaa
     2461 atggatttta tcccatatag ccatgacatc gccgttaggg agattattac atgcaagtaa
     2521 atgaatggaa gaaataccct gcaacctatc tattgttggg gctcacgacg ctgactttta
     2581 tctgtcaata tcttttaaat agctttcaag cgacgtcacc tcttagtctc tttaagatgg
     2641 gagctatgtt tgggaccttc gttcaataca atcccttaga actttggcgt cttataacac
     2701 ctatttttgt ccatataggt gtcgagcatt ttcttttcaa tatgcttacc ctttatttta
     2761 tggggaggat ggctgaacag atttttggta ctctacgttt tctagggctt tatttactag
     2821 ctggtgttat gggaaacgcc tttaccttgt tttttacacc taatgttatt gcagctggtg
     2881 cttcgacctc cttgtttggc ctattttcgg ctattgtgat tcttggttat tatagtcaca
     2941 gtcccttact caatcagttg ggccgtaatt atttggcttt gattgttatt aacttaatct
     3001 tcaacctatt tacacctagt gttgggatta caggtcatct cggtggttta gttggaggtg
     3061 ctctggcagc tatctttttg gccaataagg ttgaaagtcg cctatttagt aaggggtggc
     3121 gcttcacttc ctttttaacc tacgttacac tcttgctaat tgttctaggc tttacttatc
     3181 tttaaattaa atgaaaaatc catcgaatat tatgatatac tccccttata gtggacagtg
     3241 aaaaaataaa aattttcact agaaactata aggggagttt tattatgtcc aaaagaagtc
     3301 caaaatctgt atctgagaaa ctagaaattg ttctgcttca cttggaagaa ggtaaatcac
     3361 ttagttggtt aactagaaac caaggtatct ctaaagacac cctatcgaac tgggttcgga
     3421 agtacaaaga agctggtgtt gatgggctag aggaaagccg tcaatggaag aagtatagta
     3481 aggaactaaa ggaacaagct gtttccgact atcttaatgg cttgggaagt ctcaaagatc
     3541 tgaccaaaaa atatggaatt tctgaccctt atgttctcag atcatggata aaaagttata
     3601 ctagtggtaa agaactgaaa gctactagta aaggaatgag acgcatgaag caaggacgca
     3661 agacaacatt tgaagaacga attgagattg tcaattttac ccttgcccac gagaaagatt
     3721 accaaggggc tgttgagaag tatggtgttt cctaccagca gatctattct tgggtcagaa
     3781 agttcgagaa ggacggttct aacggtctcc tagatcgtcg tggaaaaggt cttacaagta
     3841 aaccaaacct tactccagaa gaagagttac gcctcaaaat caagcaacag gaagagcgga
     3901 ttaagtatct tgaaatggag aacggcctgc taaaaaagtt agaagaaatc aaacgacgaa
     3961 accgacggta agacttggtc ggcacttgga aaccttccaa gcgattaaag aatatgcgga
     4021 tgagtatgaa gaggtttcta tcagccactt gtgccatatt ctaaaggtat ctcgctcagg
     4081 ctattacaag tggttacaac atcaagaaac aacttctgaa caggaaaatt taggcttgat
     4141 ggatatcatc aagaaacttc atagccagca taatggtatt cttggttatc gtcgtatgac
     4201 gctatttgtc aatcgcaagc ttgaaacaaa ctacaacaag aagcggattc gacgcttgat
     4261 gcacattcta ggtctacgtt ccattatcag aagagccaag ggctattgta ctaaaactag
     4321 ctttgtcaat gtagaggaca acattctcaa tcgtaatttt acagccactg ctccaaatca
     4381 gaaatggtgt acagatgtga ctttcttgaa gtacggtttc agctgtaaag cctatttgag
     4441 tgctattaag gatctttacg acggctcaat tgtcgcctat gtagttggtc aatttaatga
     4501 taacgaattg gtattggaaa cacttcgtaa agcacaaaaa gctaatccta atgcgacacc
     4561 attaattcac agcgaccgag gttcgcagta tacttcgaaa gattattacc gtttaactac
     4621 ccagtatcag atgacccgct ccatgtctcg tgttggtaag tgtattgaca atgcaccaat
     4681 tgagagtttc tttgggcact ttaagacgga gtgctatgat ttgaagaagt ataagacttt
     4741 tgaggagcta gtttcagata ttgatgccta catctatttt tacaatcatc aacgttttca
     4801 agagcgcaat aacggccttg cccctcttga aatgaggaac aaggccgtcg cctaatattt
     4861 tattatttca ttgtccactt gacagggagc tattcaatat atgttcaaga ttatttttta
     4921 tgtttatttt tattgacctt tttgaaaaag atattaccta acaaagcaac aacaaaacct
     4981 ataataaaat ataccataga ttagctccac cagcaggttg ctccataggc aacagtacca
     5041 cctgcaccac ctagaacacc accagctaga taaccaggaa ctgagcctac aactggtaaa
     5101 actacattac ctccaaacgc tcctccgata gctcctccga tagctccttg aacagtcgct
     5161 ccacctgcgc ctccccagct acatccacca ccttcaacac tagcaagtgt ttcgaggtca
     5221 agggtgttaa ggttttcaat tgtttgagtt gccatggcaa ctacccccta aaatttttat
     5281 cgtgtgatct ctcaatcaca tctttagtat agcattcaag tgtctctatc agagctagcg
     5341 tcccaaaaag tggctatatg tcccgaatgg taattcctaa agaacatcct tcaatcattg
     5401 gaaatcttcc tctaattttc acatatttac ttaatcactt tcttattata acacttttat
     5461 gcaaatatct tatagattgc ttacagaata atcaagcaaa tgcgtttatt gtttaaaata
     5521 ttttttgact tgaaggtaag atagaaaatc acagaggatt aacaaaagca ttaatacggc
     5581 tagtactata cggtctgtgg tatcactgaa tgttagtaat gtgtaaaact ctacactaag
     5641 cactagaaat gtgatgacag gaaagacaat gaaggactgc cgtattgtta acagatttac
     5701 tgaatctgga cgcttcttaa gcatacggta gagcagtcca ttaacaaaaa tgactacgaa
     5761 agctagtgct ccgactgtta gccaagttcc tggcgagatc ttgcttttgt agagagaaag
     5821 gctgatactt ataaggaaaa ctgccaacgc agcagtgatg gttctaaaag atcgcaatac
     5881 actcgaacta atattcttta acttcatgat aaaacaccta aactatgaat aacctcagtc
     5941 agtcttgcaa acctaataag ctattacatt taactctatt cctctctgta ttttattata
     6001 cagctgtaag atttcaagta agcccttagc gattaaattc tactggagat gtaatacagt
     6061 agtgtcatta gtactgatac tttaaatagg cgaatataca tatctttgtt ttctctatta
     6121 caaagatatg caatcaaata taatataatc tccgctatca ttagcaagaa taattttact
     6181 tcgggaacat caaaaataag catttgcaag catcttacgt tcaaagtgac caaaggttac
     6241 ttttgaaact gtacccactt tttaaaaagt aagctataaa gaagcaccgt tagccctagc
     6301 aagttaatgg tatggtgaac tgcatccaag cttctaaata gattagcgag gcccattacg
     6361 atgagaatgg tagccagtaa atacggtttt gagtttttaa acatactttt ctccttaaag
     6421 tgtttttagc tagtctgtgc ataatctatg aattttatta tagattggaa gccgataaaa
     6481 aagtagtgac ataaatgtca ctacttgtct gaccttatat ccttgataac cgtacacata
     6541 agaaagagaa ataaacataa cccgataaga tttaggcatt gaagtccaaa attcagtttt
     6601 tctccaaagt tatgtaaggc aacaaggacg aagcccatag acatcattag agacactagg
     6661 cgttttttgg tcatgattac aaataactct tctcttatat cgaaattttc aatcataatt
     6721 cacatgctat tcacagacca gcaattgaca agacatttca gttaggattt cttcttaacg
     6781 gaagatttct tcttaacgga attggtagcc ttgtgttttt caagaaatga cataattggc
     6841 ttatctaaaa aactcataac agccatggaa accatcccta aaatataact tttcaaatca
     6901 aacataatcc atcaccacca gcatgttgct ccataaccaa caccacctac gatagcacct
     6961 ccagctgctc ctgcgacagc accttgccaa gtacgtgttt tgatacctag tcgtaaacca
     7021 ttaccaactc ctgtagctac tccttgttta gcaaaacctc cccagctaca tacaccacct
     7081 tcaacactag caagtgtttc gaggtcaagg gtgttaaagt tttcaattgt ttgagttgcc
     7141 atggcaacta cctcctaaaa tttttatcgt gtgatctctc aatcacatct ttagtatagc
     7201 atacaagtgt ctctatcaga gctagcgtcc caaaaagtgg ctatatgtcc cgagtagtaa
     7261 aaaaaagact gaatatcatt tttgattcag tccatgtctt attgaaaaag ctttaactaa
     7321 ttctttctat actgcctata gactccaaat aaaaagaaaa agaatcctat tgatgctaac
     7381 aaaagttgat agatatttcc tgatgacaat agtactttgc tatataaata tatcatcgca
     7441 atagtcgaaa aaatgattag gtatttcttc atttgtatca cctatctcaa atgaagatta
     7501 tttagctgta tcataacaaa atgctgtgct accgcctgca aatccagctc ctgcacctgc
     7561 gatgccaaag aaagctgcac cgacaatcgt cattccggta gtaccaataa cacattgagc
     7621 accatagcct tgaccactta cattagacaa tgcatttgta tccagttttt taaatctttc
     7681 aagttgttta ttattcataa attcctccca tacaaattag aaacagtata aggctgcacc
     7741 tactaacacc ccaccgacag ctccccacgg gccacctact gcaccaagtc ctcctactgc
     7801 cagcatcccc tcatcacagg acaacccacc ctcaacacta gcaagtgttt cgaggtcgag
     7861 ggtgttaaag ttttcaattg tttgagttgc catggcaact acctcctaaa atttttatcg
     7921 tgtgatctct caatcacatc tttagtatag cattcaagtg tctctatcag agctagcgtc
     7981 ccaaaaagtg gctatacgtc ccgaatggta atttctaatg tatccagtct ctaaaattca
     8041 gaaaaaaatt ctcattttac actcataaaa aattgaaaaa ccgttttctt tatgttacaa
     8101 tttttcaata aacagtattc gtcataaaag agaggactag accttgaaga tttacctatt
     8161 agaagataat tctattcaga tgggtcgctt ggaagatgct gtagcacatg aacttatgac
     8221 cttcggaaaa gatctatcct gtgtccagtc ttttgacaaa cctgaccagt tgttatcagc
     8281 tatcacttct aatacaagcg atcagatttt ctttcttgat attgaaatta aaggtgaaga
     8341 taagaaggga cttgatatcg ctaaaatcat acgtcaaaat aacccttatg ctatcattgc
     8401 ctttgtcact acacatatag agttcatgcc tcaagctttt ggcgttacag cctataaata
     8461 catcaataaa accttagatg aagctagctt tagaaaagaa ataggggaaa ccattgctca
     8521 agtcttccct attaacgcaa ctaccacgga tgagtttttt ctctacaaaa cagagtctca
     8581 attaataaac cttcctatgg atcaaattct atacctatcc acatcagata tcaaacacca
     8641 tgttcacctc cagactatcc ataccctcat ggatatccga gcaaatctgg cagactttaa
     8701 aaagatacac aaaaagctct acccatgcca tcggtcctat atcgtcaata cagatatgat
     8761 tatctctgtc aacttgacca attatgaagc taccttaatt aatggtcaag tcctaccagt
     8821 atcccgtatg aagataggaa agattgcaca gattgttgag gaaagaggca gaggatgtta
     8881 acaacgttat ggctactttt tctcaccctt ttaagtgcag gcctagaaat tattcttttc
     8941 ctttatttaa tgggacagaa gattcgtctg aggtattttt tcctactcct tatttttaat
     9001 ttagccttta attttattta taaccactct tcttggttta tcattaaatt ctggggtgag
     9061 gatatctatt atcttcttct ctccttcctt ttatccacta agactaaaaa accattaaaa
     9121 ataaagattt tcaatggtct cttccctgat atcctcaaca accttagttt aagattgatt
     9181 actttcttta tcttcccttt ttttaatatt agtatcaccg attatcaaag ctctctatta
     9241 atatccatcc cttcatctat tgcacctctt tgtctatcat ttctctttat taaattattc
     9301 aaggggagtt ttaccatact tcaaaagcag aaatcaaatt ctccgattca acatattatt
     9361 atagttgcta acttttttat gtttgggtac accctactgt tacagatcct catgtatctt
     9421 gaaaacacta ctcattcttc aactttggag cttcgaaaac tctgtgttgt tatttcactt
     9481 gtcctcttct tcattatgat tgtcttttta gacagaaaca ttcgtgaaat gattcaagga
     9541 caattggact tccaaaaaaa tctccagcta gaaaatctct acacctacaa taaacatatt
     9601 gaaggtctct acaattctgt tcgtagtttt agacacgatt atagtaatct cttagtcaca
     9661 ttacgattgg ggatagataa agacgatatg gatattgtca aagaagccta tgatagtgtg
     9721 cttcaagaat ccgataaacg attaaataca agaaactttg acttagctag actcgttaat
     9781 attcaggata acactttgaa aagccttctg tccgcaaaag ttttacaagc agaagaagaa
     9841 ggtattgaag ctcagattag catcccagaa cccatccact tgattgggat ggagactctg
     9901 gacttcatta tcgtcacttc tattttttta gataacgcta ttgaaggtgc cattcaaact
     9961 caaaacccta aaattactat tagcttttgg gaagatcatt gttcacagct attatctatt
    10021 agcaatacca taagtgaaga aaaaacagaa accaaaacca tatttgaaag aggtgtctcc
    10081 aacaagggac gagagcgagg cattggcctt gctaatgtca cagaaatctt agataactat
    10141 atcaatgtaa acttagaaac acagagtaac aatttctcat tcacacaaca attaacaata
    10201 actaaaaagg cctaacagcc ttttttctat acctaagctt gaggaatgtt atagtctttt
    10261 gttggaagcg ttctttgccc tccgaatcct tttaggaaac catttatata atccatccac
    10321 ccacttccac ctacgacttg ttcaagagcg tggttatcaa gtgtttcaaa gttattaatc
    10381 gtattgttag ccatcagtaa ttctcctcct attggtcttg caagtttagt aacttgtctt
    10441 taaagtaatt gaagtaggtc ttttggtcaa taacgcttgt cacacgacct tctagaccgt
    10501 aacgtagatt ttgggcttct ttttctgaaa tacttgccct agcagttact ctaaacacat
    10561 tccccctttc tgtttccgtg gcagaattat caatactctc aagttttcca ataattgtgg
    10621 taccgtgatt accaacctta tccaaggtca gtcgaactga ctggcctttt tgcagttttg
    10681 gcacataatc cgaattcaca taataagtaa tggcaacttc ctgggtttga gtcatatcgg
    10741 gataaagctg ggccaactca gttcctgtcg cagccatggt tgctttttta tcagcttgac
    10801 tcaagtgtaa gattccatct tctggtgact ggatgagggt attagtcaga aggacatctg
    10861 cctgattgat tttactctcg gtatcgttaa tttgtgtttc cactgagctc aattgctgtc
    10921 ctgcattttg caagaattga ttttttagag cttctttttt agtgctatca ctattgtcat
    10981 aagttacaac tgtgcctgtc ccagcctttt ggatttctag attacctatg gaagcattca
    11041 agctcgaaat attggtatta acttgagata ggtattggtc tgttacactg gcatccggtg
    11101 tcgtagcata ctgactgtta taggcattta aggttgcctg atgaggattg ccttcaggta
    11161 aagtcgtttc atgattggta atagcttgag agagcgcctc atactctgag acctgagtct
    11221 gcaattgact aatctggtta tcaatagcag aaccggtatt actcgcaatt gctgcttggt
    11281 tattaacctc tgtatttgtt ttagccacac ccaagtcaat atcctgtgcc tgacttaggt
    11341 aggtgttaaa agtactctga taaccaaact cgtcttcctg ttcttggaaa agattggttc
    11401 cctgcgttag gctagattgc aaggtcttca aacctgattc ctgtcttttt aaaagttcta
    11461 gttgcttttg aagcccctct ttttgcgatg cctccatggt ctctgaatac tgaactaagg
    11521 tgtccccttt tttaacaacc ttattagcaa ccagttgatt atctatgatg gtattgtcac
    11581 tggttgattg gattactgcg ataaccttgg ttggctctat acttcctcta gacgtgactg
    11641 taacttcctt cttagcaaaa aaagcgaaaa gaaaaaggaa aataactaac aaaatcaagg
    11701 gagtaatcaa aacagtagac atattgtggt agcgacgatg gtaaaactct gtgcttttaa
    11761 acaactgtgg attcatcgtg tttccttttc ctcactttct aaataattga taatagaaac
    11821 ctggataaga cattaggtct tgatgagaac ctgtctccac tacgcgtccg tgatcaatga
    11881 ctacgatacg gtcggtccgc tcagcgatac taagcctgtg tgctacaaag atgatcgttt
    11941 tatcttttag tgctaggagg ttatcaataa cctgcttttc tgtcaaaaca tccaatccgc
    12001 tagttgcttc atctaagatt agtacaggag atttcgttag tagtgcacgc gccaaagcga
    12061 tacgttgctt ttgccctcca gacagacctg ctccatcaga cagctctgtc tgaaacccca
    12121 taggcatgtt ttcaatatct tgacgaattt ctgctatttc acaagctttc aaaatatcag
    12181 cttgcgtaat accccgtgct gcacctaaag taagattttc taaaacacta ccactaaata
    12241 tataggattg ctgagggaga tagttaatat gttgacgaag agttttcttg tctatgcgac
    12301 taatattttg accattaaaa tctatgtgcc ccttatatgg ttgataaaaa ttgaccaaca
    12361 ttttagctag agtagtctta ccagatccac tgacaccaac aaaactgatt ttttctcctt
    12421 gtctaatcgt caaacagaca tcagtcaaag tatcacgacc aaaaccatat ttataagata
    12481 aatccgtaac agtgatatct ccatccgcaa tgccttcttg ataggtatca tcactttgtc
    12541 caaactctga ttcaatcaga tagacctcat tgagcctagt attagctacc ttagcagact
    12601 gtaacttggt ttgcaggtta atgatatttt ccaaaggatt cgtgaagtaa gaaagcaaca
    12661 tattaaaagt aatcaattgt cctatcgaaa tggtatttcc catcaccaac tgagcacctg
    12721 tccagaggat aagtacattt aaaataagtt gagcaccttg tttcaatgat gtttgtagta
    12781 tagataactt agaaaggcga aaagaattgt ctagatagtc aataaactca ccatcaatct
    12841 tttgatagca tactttttcg ctggttagtg actttatggt ttcaatccca ttaatgtcct
    12901 caatgatggc tgaattaacc atagcattac tctgcatgac gtcatgattc attcgctcaa
    12961 aaggtttcat aaaggcaaag acgataaggg tataaattgg aaccgaacaa agaactagct
    13021 tgaagagatt gctattttgt atcaataaca cgcctcctac gataatcaca atagagaaat
    13081 caaggaaaag tgataatatc gtcgaagcca gagcatcgat aatagagtta gcatcactaa
    13141 aacgtgagat aacctcccct gtacgtcttg tggcaaaaaa agacattggg agttcaaaga
    13201 tatgtcgtat gtaggacaag ataacgtcaa tggtcaatcg ctgactcagt atggttaaga
    13261 gataatctct tgcaaaagtc atcatttgtt gtaaaacata ggtcacaact aatccaattg
    13321 agataattcc taaggtagac ttcatttgat taggacatat tcgtctagaa taccttgtaa
    13381 ataataggaa cctaaaatat ttattaaagt aaccaagaga ctggcaaaga caatattagc
    13441 tatcaaggac ctttgtttaa agatcaaagg gagaaagtcc cagagtccat ttttcttatc
    13501 cttatgtggt ttataactgg gttccggtcc cataaaaaga gtaacacctg tccactcttt
    13561 ctcaaaacgc tctttagtca ttttagttac ttttacactt ggatcagggt ctccaattat
    13621 cagataatcc ttggtgcttt tataaataac ataataatgt tgaagcttcc catctttatt
    13681 aacatgagca ataaaaggat aaggaacatc ttccatctca aagagcgaca tttcagcctt
    13741 tatagctctc gtttcaaagc caattttttt agcagcctct acaagaccta aggcagttgt
    13801 cccttcttta ttggtcttcg ccaactcacg cagatgtgct aatgaataat ctgaaccata
    13861 gtacttggcc actgatgcca aggcagcaac tccacaatcc ctcatatcta tttgagggac
    13921 aaaagtccta cgaaaacgaa acataccaaa ccctttcatc acaaattatc atatgattag
    13981 tatgtcatat tttcaggata aaaagagcca gcgtcccaaa aagttgccat acgtcccaaa
    14041 cggtaagaaa aatcttaaag tcatctccac tattaccatt taagccgtat ttggggtcat
    14101 ttaggacaag ttcattgaaa tcgatttcaa agttatacaa tagttattag aaggaaacat
    14161 tctaaaatag tcctacaagc atacgtattt gatctaacca ttattactgt gccagccctg
    14221 gtatttccaa aggaaaccat gactgctgat agcctcggag cctatctcta tcgtatgatg
    14281 tcataatttg attattttta ttccgaaaag ggataacatt atgaaaaacg tcaatccata
    14341 tctcaaaaaa tcctatcaaa aaaggctaaa tcagcctctt gagattcgat tactcaatta
    14401 tcggtttaat tttccttagc tttgtaagtg tatttgttat cactgtcaat gctattttta
    14461 gcgtcactag aggggttccc ttccttaatg cccaccttat ttccaccttg agtaattgtg
    14521 ccttctatct tttgatttac tcaaccttga ggtggcacca tctcaaaaag ctctataatc
    14581 tctacagtgg tttttcccac tacagaaatt atagagccga agttaagtag ttctgtggta
    14641 aactgagtca taggaataaa tctctttcta gtaatgtttt gcaactctac tataacggat
    14701 ttattccttt tt
//
