LOCUS       gnlProkkaNKIHKOBL_3    15305 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|NKIHKOBL_3.
ACCESSION   gnlProkkaNKIHKOBL_3
VERSION     gnlProkkaNKIHKOBL_3
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:59:47
            Original ID  :: gnl|Prokka|NKIHKOBL_3
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15305
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15305
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1251:5305]"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1252..5305
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-i"
                     /protocluster_number="1"
     cand_cluster    1..15305
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="((LANC_like and (Lant_dehydr_N or
                     Lant_dehydr_C)) and not (YcaO or TIGR03604))"
                     /kind="single"
                     /product="lanthipeptide-class-i"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..15305
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-i"
                     /region_number="1"
                     /rules="((LANC_like and (Lant_dehydr_N or Lant_dehydr_C))
                     and not (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             2..103
                     /locus_tag="ctg3_1"
                     /transl_table=11
                     /translation="MIIGHMGLFFYNQKGSIISIEDLPTTEIIEPFF"
     CDS             complement(139..312)
                     /locus_tag="ctg3_2"
                     /transl_table=11
                     /translation="MNSVRRRHPELSPASPHKLRHTGATLARKSGVPLEIISEALTHSD
                     KQITKTYVNTKI"
     CDS             456..719
                     /locus_tag="ctg3_3"
                     /transl_table=11
                     /translation="MAHDFASWVSGDSMEPKYHNGSVALIRETGFDYDGAVYAVVCNSQ
                     TYIKRVYLEAEGLRLKYKDIFISYDEDPRVVRIIIGNFIPLK"
     CDS             969..1073
                     /locus_tag="ctg3_4"
                     /transl_table=11
                     /translation="MENTEFSLELDVTEVSTEQGYVSGGVTSTGCCKD"
     CDS             1252..1530
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_5"
                     /sec_met_domain="Lant_dehydr_N (E-value: 5.8e-15, bitscore:
                     45.2, seeds: 73, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLLVANPQFFHNLTKEKIYKNSTFRNYVKRSITRATPFGLFSSIG
                     VGTFSDISYHQKIGENYTKKISVSGEWLSSICMMLENKDSVLLQLHI"
     CDS             1681..4044
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: Lant_dehydr_C"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1155:Lantibiotic dehydratase domain protein (Score:
                     577; E-value: 1.1e-174)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_6"
                     /sec_met_domain="Lant_dehydr_N (E-value: 6.3e-65, bitscore:
                     210.3, seeds: 73, tool: rule-based-clusters)"
                     /sec_met_domain="Lant_dehydr_C (E-value: 8.3e-19, bitscore:
                     59.0, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLELVLQSKSPDLEKQKILDYIRNLITNEFLFTNLRKVAISHKDL
                     DDLTNILKDINNQRKLTEDLLQIKNSIEQYAKLELGEGISQYTEICKKMSYIFNDKKQH
                     YLKVDLVNCCDSVLPKNLKKKMEDFVNFISKINLAKGYRNRELESFTEKFVEKYGEYVE
                     VPIKELLDGNLGLGLPKQTLGTHVKSSSSVEEQNFLSYLSKEVFKAVKNCKKEIDISNI
                     PLGLLYPNSDRFVANQLELYCEIKNFESQPVISVVPNTGSDMIGKSIGRFASYFPNSYI
                     SLDSQLDNVELIEFPRDSKNLNVMSAQNAHSKKLLLSYDDNDNTSIELDSVVVGVIKTE
                     YRYKLYFRDLRTGSIVNFVTTSMLNHKSNGVFSDLARFLLAVSLEWQDNPFSVFRIIEN
                     FDYLPYIPKIKYGNIILSEEKWVLSDIDKNDLSSIKQWKKDFDVPRLLYFHKADERLLV
                     DLENDLDTQWLLKQNVDKLYFTRFEKYDGKNCEFIFGFENYQSSINHYSMQEKSVRRLT
                     NNFYKNYVKTFSSDWIYFRLYGINSSILLELRERLLLFTDELLVEKLISDFHFVNYSDK
                     DNGSLRLRFKINNDDNFEDLRFRIAHWIDFLLESGFCNDVSFNLYEREIERYGGDNFIT
                     VCERMFSIDSFLTLKLFSKKLLNDKDLFSVLHSTFLYIRLLGIPLKRLLELLKGNLTQN
                     RYRKSFKKLFPNNTIVVKEFKEYFDYKNQFEIFNEVFREFPPIDGYFEGKNDIVYSLLH
                     MHMNRVGMFPYREKEYLYFIMYIAEPLNNYKEFT"
     CDS             4082..5305
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-i: LANC_like"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1140:Lanthionine synthetase C family protein (Score:
                     308.8; E-value: 9.3e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_7"
                     /sec_met_domain="LANC_like (E-value: 2.9e-52, bitscore:
                     168.4, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLDSDIIDRLQRAYYTENRSYLSEYPSIIIYLSYRLINCDNKEYS
                     KLLYNRVNYYLQELLKSIKLNSTNNISLCYGFTGYVYALEFLSKNCKGYDKLLDTLETI
                     LLALTKDRLREIKSSNIVKEEYFDVIQGVSSVARYLLSKEESTSEQELLVKEILNYFAD
                     LIINEPTIYVEYMPNEKLRKRFPSGYINLGVAHGILGPLYVLALGFEKFNITKHIPSIE
                     KGLSYYENAFFTNTIGKIIGWNGRVSDYEENEEFRFNISWCYGSLGMARVLYNIAKIID
                     SQKLREMAMDVFTSSIDYLNSSEILNNGICHGRSGIMLLFNLMYLDTGKTQFKAISDNL
                     FKEIINDASNSEYIFVERDIYFRGVTFDEVIDYIDFGLLNGVSGIVITLMAQRTGNAYP
                     LDRMLFMQ"
     CDS             5329..6594
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 93.6; E-value: 2e-28)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_8"
                     /transl_table=11
                     /translation="MRKILKNKLYLKVLVSDLISNFGDTLYFIALMTYVTEIKESNLAI
                     SIVNISETLPILFTIFFGIIADKTLNKVKMIIKTLWLRVILYLLVAVAMNFKPSIIVVI
                     IASLVNLVADTLGQFENGLFYPISNRIVKKSDREETMAFRQTVVSTMNIVNQSLGAFLI
                     TFFSFSHLAFINSLTFAISLLIMLAIRNQINSYYDETISTSKISQFDFKASFSEIISNL
                     KLSINHLFSIGNMKEALLVIPILNGSLAILIPLVVVNLSKDSNLTIVNSAITISLLGIS
                     TVSGGILGGTLILISKKFKSLSIGTLLKMNLTIVLLSFVAFYFQNIYLIILSSFLSSVL
                     VSALNPKMGTIIFNNIDETKLATIFGGMVTYFQIGDIVSRLLFSTLVIYLPYGYIALIY
                     IAVVFVAILYTLKSSNHIEREF"
     CDS             6822..7334
                     /locus_tag="ctg3_9"
                     /transl_table=11
                     /translation="MMFDDRLEIYSPGKLPNIVTVENIKHERFSRNPRIARTLTEFGWV
                     REMNEGVKRIYSEMESYFLHEPKYTEPGNKVVLTLENNILSRHLRVNDKMMKKYDEFND
                     LNDDEKAILHIMYNTGEKMTTALAARITNRGRNFASKLLKSLVNKEILEWHGTSKQDRN
                     QYYTLAE"
     CDS             complement(7671..8888)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 110.6; E-value: 2.2e-33)"
                     /gene_kind="other"
                     /locus_tag="ctg3_10"
                     /transl_table=11
                     /translation="MSIKKTKNGTYQLRLYIPEDVQAKLGLGKLFERKYKTRREAKEVE
                     LKLSIDIKNAKSGKSHINIKNKGEIIFKKFYEDIWLEPYKAGQTTTTIKPPTKATVFQT
                     ENIFRLHILPILGKYSIEYPNNNKQLILSLLTPKANSYANFKVIRSYVNSVFDWAEELE
                     YIPSNKLRKTITRIKANKKILLKESKREEDLSLDKEELKLWLQAFDIDLEKGLIDLKDY
                     TLFYTTFFLSDRKSESYALQWKHINFSTGETLIEQALDRFGNIKPTKGRKKTLFKTPIE
                     LIELLANWKARQQEELKLFGLRQTQKQFVFTYNDRSNNINLPLHVDYLNYRMKSVRRRH
                     PELAPASPHKLRHAGVTLAKQAGYSLEAISEALTHSDKQITKTYVNTKDIVNRTVGDIA
                     FRSLKK"
     CDS             complement(8899..9171)
                     /locus_tag="ctg3_11"
                     /transl_table=11
                     /translation="MLVQLPEEQTQEIQQMIATLIKNEIHHFKEDIGADSTFLNKKQTY
                     NYLGISNNTLDIGIAMGLPYIRIGKSISFNKKSINQWMTRLEISA"
     CDS             complement(9233..10423)
                     /locus_tag="ctg3_12"
                     /transl_table=11
                     /translation="MIKESFPFDILNLFDTKGTPPFNFSNQYLNPNTKILDFNNATLYE
                     VDFDSLSPDTKAKLQEGAYKIGESRKVEGNLRAVIVDTTDQKNRVEDLTLRKMTNNNEN
                     QVPSDLIAQAQLKQIYNLLLDIKESQDYQIRWERNNSILAPFYSARTKVIEANNSKDFR
                     EKVKSLKDANTLFEESVSAIKSDIISNRDEIIKKISQPTYRQASLQTHADFLLQDIEIM
                     TKIVGMQIYIDLTLNNEGIAHDRLLSFQGSMELVSKQNIPYKTNYLKELAKKLLYVKEL
                     KWIKNNSIPKVSLLELIHNHYSYSKNNRDLFININTKLIEFHQDSNVNLSNTETAKIET
                     EKKMTLKTKKCKTCKKTISSPKTIPICDACRNKGKQLTVVGVALLVFFNKIINKKN"
     CDS             complement(10670..10927)
                     /locus_tag="ctg3_13"
                     /transl_table=11
                     /translation="MGNGGQWMNAPGYQTTHTPTEHSALSFSPGQAGADPTYGHIAFVE
                     QVKSDGSILISESNIKGLGVVSYRTFDAETAKQITYVIGH"
     CDS             complement(10903..11244)
                     /locus_tag="ctg3_14"
                     /transl_table=11
                     /translation="MVLSTRQQMVASTSPIPLALGKGVLKPCKNSIPISMSMEVHQKPL
                     NRRKEKPETEAVSQQGMSHKAIASPKKSIPQATQDCLILGDNVPGLSITEEKKSVLASE
                     SIWEMVANG"
     CDS             complement(11435..11623)
                     /locus_tag="ctg3_15"
                     /transl_table=11
                     /translation="MIEQDHRPVKRHNKFYRSLRTASTTIKGMEAIRGLYKKTRKEGTL
                     FGFSVCTEIKVLLGIPA"
     CDS             complement(11629..12123)
                     /locus_tag="ctg3_16"
                     /transl_table=11
                     /translation="MTINHFKGKQFQQDVIIVTVGYYLRYNLSYREVQEILYDRGINVS
                     HTTIYRWVQEYGKLLYQIWKKKNKKSFYSWKMDEIYIKIKGKWHYLYRAIDADGLTLDI
                     WLRKKRDTQTAYAFLERLVKQFDEPKVVVTDKAPSITSAFKKLREYGAFIKGQNIVPLN
                     T"
     CDS             12273..13490
                     /locus_tag="ctg3_17"
                     /transl_table=11
                     /translation="MKQSQAKKHDNTMTNKILMRLIALVLGLLFLEILIIHSKNEQQKS
                     VSNQVQTARIMANGDLLYHDGLYMSALQADGSYDFTENFTYVKPWLKQADLVLGDFEGT
                     INPDYPLSGYPLFNAPQSVTAAISDAGYDVMDLAHNHILDSGLEGAFTTADAFKEVGID
                     PVGVYENPVRDKAPLFIKNVNGIKVAILSYAYGFNGLESNLTEKEIANHLSNLDEKRMK
                     VEIERAEKEADVTVIMPQMGVEYRLEPTDEQVKLYHKMIDWGADIIFGGHPHVVEPSEV
                     VKKDGQQKLIIYSMGNFISNQRIETMDGVDSAAWTERGVLMDVTLEKKNCQTTIKTAQA
                     HPTWVNRTPKGTISPEGYPLYTYQTYILEDFIKGGKYRNKLDEETKERIDTAYKEMNAH
                     VNLKWK"
     CDS             13811..14077
                     /locus_tag="ctg3_18"
                     /transl_table=11
                     /translation="MKAIITVVGKDKAGIVAGVATKIAELGLNIDDITQTILDEFFTMM
                     AVVSSEDKKDFTHLRAELEAFGESLNVKINIQSSAIFDAMHNL"
ORIGIN
        1 tttcattata ggtcatatgg gacttttttt ctacaatcaa aaaggctcca taatctccat
       61 agaggattta cccactacag aaattataga gccatttttt taagcttcta tatgcaatat
      121 ctccagcagt ttgatttact atatttttgt gttaacatag gtctttgtaa tttgtttatc
      181 actatgagtt aatgcctcgg aaataatttc taggggaacg ccagattttc ttgcaagagt
      241 ggcacctgtg tgtcttaact tatgtggtga agcaggggat agttctggat gcctacgtct
      301 gacagaattc attctatagt tgaggtaatc tgtatgaagt ggaaggttga tattattgga
      361 tcggtcatta taggtaaaca caaactgctt ttgagtctgg tgtaaaccaa atagttttaa
      421 ttccttatta tgaaacggtt tactttacgg aggagttggc gcatgacttt gcctcatggg
      481 tgtctggaga ttctatggag ccaaagtatc acaatggttc agttgctctc attcgtgaaa
      541 caggttttga ctatgatggt gccgtatatg ctgtggtatg taatagtcaa acatacatta
      601 agcgagtata tcttgaagca gagggtctac gtctaaagta taaggatatc tttatttctt
      661 atgacgagga tccacgagta gtgagaatta ttattggaaa ttttatacct ctcaaataat
      721 acgtttttct agtcctgaat tgtcaacttg tttgcttttt tgataatgat tctagttttc
      781 aaaaatgtaa tgacatctgt taaggatttc ttatgaaata tcttctgata acagagcttg
      841 tttgatagta cagacggatt ttattttata atactccgaa acaaaaagaa tgaattttct
      901 aaaaattatt gacaaataaa tttgctttta gtattataaa cacaacttaa agaagaggca
      961 gagttatcat ggaaaatact gaattttcat tggaacttga tgtaactgaa gtttcaacag
     1021 aacaaggtta tgtttctggt ggtgtaacat ctacaggttg ttgtaaagat tagttttata
     1081 attgattgaa taaggcaggt atacgaggta cttacctttt tttacaagag aattatgttt
     1141 aagataaaag ataattacat ttataggtaa tgcgttaatg attcaagact tatagaaaaa
     1201 cttagtgaaa ataatcttga aatatttttt gataacaaag tttttaaaga aatgttgcta
     1261 gtggcgaacc ctcaattttt ccataattta actaaagaaa aaatatataa aaattccacc
     1321 tttagaaact atgtaaaaag atcaattaca agagcaacgc cgtttggatt gtttagttca
     1381 attggtgtag gaactttttc tgatatctca tatcatcaaa agattggaga aaattatacg
     1441 aaaaaaatct cggttagtgg agagtggcta agttcgattt gtatgatgtt agaaaataaa
     1501 gattctgtct tattacaact acatatatag tggaaccaaa aagtacttga attatcagat
     1561 aagtatcaat taagtaatgt caattactgg ggaatctctg agataagtaa ggatttattt
     1621 atcaagaaaa ctggactttt agaattcata caaaaattaa cgtataaatc ggaagtcagt
     1681 gtgttagaac tggtacttca aagtaaatct cctgatttag agaagcagaa aattttagat
     1741 tatatacgta atttgattac taatgaattt ttgtttacaa acttgcgaaa agttgcaata
     1801 agccataaag atttagatga tttaaccaac attttaaagg atattaataa ccaaagaaaa
     1861 ttaaccgagg atttattaca aataaaaaat agtattgagc agtatgcaaa attagagttg
     1921 ggagaaggca tttctcaata tactgaaatt tgtaaaaaaa tgtcgtatat ttttaatgat
     1981 aaaaaacagc attacctgaa ggtggattta gtaaattgtt gtgattcggt gctgcccaaa
     2041 aatttaaaaa agaaaatgga ggattttgtt aattttattt caaaaattaa tctggctaaa
     2101 ggttatcgaa acagagaatt agaatcattt acagaaaaat ttgttgaaaa atatggagaa
     2161 tacgtagaag ttccaattaa agaattatta gatggtaatt taggactggg tttaccaaaa
     2221 caaactttgg gaactcatgt aaagtcatca agtagtgtag aagagcaaaa ttttttgtct
     2281 tatctgagta aagaagtctt caaagctgtt aaaaattgta aaaaagagat agatatatca
     2341 aatatacctt taggattgtt atacccaaat tcggatagat ttgttgcaaa tcagttagag
     2401 ttatattgtg aaattaagaa ttttgaatct caacctgtta tatcagttgt cccaaataca
     2461 gggagtgaca tgatagggaa gtctattgga aggtttgcct cctattttcc taattcttat
     2521 atctcgttag attcacagtt ggataatgta gaattaatag aatttccaag agatagtaag
     2581 aatttaaatg ttatgtcggc acagaatgct cattctaaaa agttattatt atcttatgat
     2641 gacaatgata acacatcgat tgaattagat tctgtggtgg tgggggttat aaaaacagaa
     2701 tatcgatata aattatattt tagggattta cgaaccggct caattgttaa ttttgtaaca
     2761 acatcaatgc taaatcataa atcaaatgga gtatttagcg atttagcaag atttttgcta
     2821 gcggtttctt tagaatggca agataatccg ttttcagtgt ttaggataat tgaaaatttt
     2881 gattatcttc cctatattcc caaaattaaa tatggaaata taattttaag tgaagagaag
     2941 tgggttttgt cagatataga taaaaatgat ttatcttcta ttaaacagtg gaaaaaagat
     3001 tttgatgtac ctagactact gtattttcat aaagctgatg agcgtctatt ggtcgattta
     3061 gagaatgatt tagatacaca gtggctttta aaacaaaatg tggataaact gtattttaca
     3121 cgttttgaaa aatatgatgg taaaaattgt gagtttatct ttggatttga aaattatcaa
     3181 agtagtataa atcattattc tatgcaggaa aaatctgtta gaagattgac aaataacttt
     3241 tataagaact atgttaaaac attttcgagt gattggatct attttagatt atatggaatt
     3301 aattcatcaa ttctacttga actaagagag cggcttcttt tgtttacaga cgagctattg
     3361 gttgaaaagc taattagtga ttttcatttt gtaaattata gcgataagga taatggatcg
     3421 cttcgattac gatttaaaat aaataacgat gataattttg aagatttaag atttcgaatt
     3481 gcacattgga tagacttcct actagaaagt ggtttttgta atgatgttag ttttaattta
     3541 tatgagaggg aaattgagag atatggtgga gataacttta taacagtttg tgagaggatg
     3601 ttttctattg acagttttct taccctaaag ttattttcga agaaattatt aaatgataaa
     3661 gatttatttt ctgttttgca ttcgacattt ttatatattc gattattagg gatcccatta
     3721 aagcgattac ttgagttgct gaaggggaat ttgactcaaa atagatatcg taaaagtttt
     3781 aaaaagttat tcccaaataa cacaatagta gtaaaggaat tcaaagaata ttttgattac
     3841 aaaaatcagt ttgaaatttt taatgaagta tttagagagt tcccgcctat tgatggatat
     3901 tttgaaggta aaaatgatat agtctatagt ttacttcata tgcatatgaa tagagtaggc
     3961 atgtttccat atagagaaaa ggaatatctt tattttatca tgtatattgc agagccgttg
     4021 aataattata aggaatttac ttaaaaagta tgaagaaatt atctgtaaag tagataaact
     4081 cgtgttggat agtgatatta ttgacagatt gcagagagca tattatacag aaaatagaag
     4141 ttacttatca gaatatccaa gtataattat atatttatcc tataggttga taaattgtga
     4201 taataaggag tattctaagc ttctctataa tagagtaaat tattatctac aagaattgct
     4261 aaagtctatt aaattgaata gcactaataa tatttcactt tgctatggat ttacgggcta
     4321 tgtatatgcc ttggaatttt tatctaaaaa ttgtaaagga tatgataaat tactagatac
     4381 acttgagaca attttattag ctttaacaaa agataggcta cgtgaaataa aaagctctaa
     4441 tattgttaaa gaagaatact ttgatgtaat tcaaggtgtc tctagtgtag ctagatattt
     4501 gcttagcaaa gaggaatcaa cttctgaaca agagttatta gtaaaagaaa tattaaatta
     4561 ctttgcagac ctaataatta acgagccaac tatttatgtg gaatatatgc caaatgaaaa
     4621 attaaggaaa agatttccta gtggctatat taatctaggt gtagctcacg gtatattggg
     4681 accactatac gtgttggcgt taggatttga aaaatttaat ataacaaaac acataccttc
     4741 aatagaaaag ggcttgagtt actatgagaa cgcctttttt accaatacaa ttggaaaaat
     4801 aattggttgg aatggtagag tcagtgatta tgaggagaat gaggaattta gatttaatat
     4861 aagttggtgc tatggcagtc ttggaatggc aagagtacta tataatatag cgaaaatcat
     4921 tgatagtcag aaattacgag aaatggcgat ggatgtattt acttcatcta ttgattacct
     4981 taatagcagt gagattttaa ataatggaat ttgtcatgga cggtctggaa taatgctttt
     5041 gttcaatttg atgtatttag atacaggaaa gacacaattt aaagcaattt ctgataattt
     5101 atttaaagaa attataaatg atgcttctaa ttctgagtat atatttgtgg agcgtgacat
     5161 atattttaga ggcgtaacct ttgatgaagt tattgattat attgactttg gattgctaaa
     5221 tggtgtttca gggatagtta taactctaat ggcacaaagg actggaaatg cctacccatt
     5281 ggatagaatg ctgtttatgc agtgaagttt ttaagttaaa ggagaagtat gagaaaaatc
     5341 ttaaaaaaca aactatatct aaaagttctg gtttcggatt tgatatcaaa ttttggagat
     5401 acattatatt ttatagctct catgacctat gttacggaga ttaaggagag taatttagct
     5461 atttcaatcg taaatatatc ggaaactcta cctattttat ttacaatatt ttttggtatc
     5521 attgcagata aaacgcttaa taaagtgaaa atgattatta aaacgttatg gctacgggtg
     5581 attctatatt tattggttgc tgtggctatg aattttaaac cttctattat agtagtcata
     5641 attgctagtc tcgttaatct tgttgcagat acattgggac aatttgaaaa tggtcttttt
     5701 tatccaattt ctaatcgaat agtgaaaaag tcagatagag aagaaactat ggcgtttagg
     5761 cagactgttg tttctacgat gaatattgta aatcaatcat tgggggcgtt tttaattact
     5821 ttttttagtt tttctcactt agcttttata aattctctaa cttttgctat tagtctgtta
     5881 attatgttag caatcagaaa tcaaattaat agctattatg acgagacgat ttcgactagt
     5941 aagatatctc aatttgactt taaagcttca ttttctgaga ttatttcaaa tttaaagctc
     6001 tcgattaacc atctatttag tatcggaaac atgaaggaag ctttacttgt tatacctatt
     6061 ctcaatggga gtttggcaat tctcattcca ttagttgttg ttaatctttc taaagattct
     6121 aatttgacaa ttgttaattc tgcgattacg atctcgcttt taggaattag cactgtttca
     6181 ggaggaatac ttgggggcac tttaattcta attagtaaaa aatttaaaag cctttccata
     6241 ggcactttgc taaaaatgaa tttaacgatt gttttactat cattcgttgc tttttacttc
     6301 caaaatattt atttaattat attatcatca tttctttcga gtgtattagt tagtgcatta
     6361 aatcctaaaa tggggactat catatttaat aatattgatg agacgaagtt ggctacaata
     6421 tttggaggaa tggtgacata tttccaaata ggggatattg tgtcaaggtt attgttttct
     6481 acattagtga tttacttacc gtatggttat atcgcattaa tatatatagc agttgttttt
     6541 gtggcaattt tatatacatt aaaaagttca aatcacatag aaagggaatt ttaaattagt
     6601 taaatgatta tagttttcca aattttctac tatgaaaacc tattttcaag attgagtact
     6661 aaagttcgag attttgttcg tactcagctt agagaatttc aatatttgga tgatgggcaa
     6721 tttaaaacat taccagagta tccagaattt gcttggtttg aagggatgta aatgcggtaa
     6781 ctcatagaaa ttgctccatt tttggcgatt atatccgaat tatgatgttt gatgatcgat
     6841 tagaaattta tagtccaggt aagcttccta atatcgtaac ggttgaaaat attaagcacg
     6901 aacgtttttc tcgtaatcct cgtattgcta gaactttaac agaatttgga tgggtacgag
     6961 aaatgaatga gggagtgaag cgaatctatt ctgagatgga atcttatttc ttgcatgaac
     7021 ctaaatacac agagccagga aataaagttg ttttaactct tgaaaataat attttgagcc
     7081 gacatttgag agttaatgat aagatgatga aaaaatatga cgaattcaat gatttaaatg
     7141 acgatgagaa agcaatttta catatcatgt ataataccgg agagaaaatg actactgctt
     7201 tggccgctag aataacaaat aggggtagaa attttgcaag taaattatta aagagtcttg
     7261 taaataaaga gatcctggaa tggcatggca caagtaagca agatagaaat cagtactata
     7321 ctttggcaga atagcggatc tatttataac tggagtgcag aagagtgcag tagttcggag
     7381 taaaacgcag taagtgaatt tcccctgttt tcctcaaaaa atctcaaact ttttgaaatt
     7441 ctggacaaaa gaaaaggcct agttgcctgt agtttctacc tattaagtta tattgaaatt
     7501 cattggttta aaaccagatc ttaagaaagc tcgtaaagct tcacaattct caaaacgtta
     7561 atcaatacga ttatatcaat gtttcaagac attcaagagt tatctcttgg gtgtcttttt
     7621 ttattcaaaa ttcgatagtt tccaccaaag tttccaccaa ttttccacca ttattttttc
     7681 aagctacgaa atgcaatatc gcctactgtc cgattaacta tatcttttgt atttacataa
     7741 gtctttgtaa tttgcttatc actatgagtt agagcttctg aaatagcttc aagagaataa
     7801 cctgcttgtt tggcaagagt aacacctgca tgtcttagtt tgtgtggtga tgctggtgca
     7861 agttctggat gtctccgtct gactgacttc attctataat ttagataatc cacgtgaaga
     7921 ggtaaattaa tgttgtttga acgatcatta taggtgaata caaactgctt ttgagtttga
     7981 cgcaatccaa ataattttaa ctcctcttgt tgtcttgctt tccaattagc taatagctca
     8041 attaattcaa taggtgtttt aaaaagggtc ttcttacgac ctttggtggg ttttatattt
     8101 ccgaaacgat ctaaagcttg ttctatcagt gtttctccag tagagaaatt gatgtgtttc
     8161 cattgaagag cataactttc tgattttcta tcggataaaa agaatgtcgt ataaaagaga
     8221 gtgtagtctt ttaaatcaat aagtcctttc tctaagtcta tgtcaaaagc ttgtaaccat
     8281 aatttcagct cttctttatc gagagataaa tcttcctctc gtttgctttc tttaaggaga
     8341 atctttttat tagctttaat tctagtaatt gttttgcgga gtttatttga tggaatatat
     8401 tctagttcct cagcccaatc gaaaacagaa ttaacatagc tcctaattac tttgaaatta
     8461 gcatagctat ttgctttggg agtaagtaat gaaagaataa gttgtttatt attatttggg
     8521 tattcgatag aatatttacc cagaatgggt aaaatgtgta gcctgaatat attttctgtt
     8581 tggaaaactg ttgcttttgt gggtggtttt attgttgttg tggtttgacc tgctttgtat
     8641 ggttcgagcc aaatatcttc ataaaatttt ttgaatatga tttctccttt attttttatg
     8701 tttatatggc tttttccaga cttagcattt ttaatgtcga tagaaagttt taattctact
     8761 tctttggctt ctcgtctggt tttatatttt ctttcaaaaa gtttacctaa acccaatttt
     8821 gcttgaacat cttctggaat gtaaagtcgt aattgatatg ttccattttt tgttttctta
     8881 atagacatat ttacctcctt atgcgctgat ttctaatctt gtcatccatt gattgatact
     8941 tttcttgttg aaactaatag attttccgat tcggatatag ggtaatccca ttgcaatccc
     9001 aatatcaagt gtattattag agatacctag gtagttgtaa gtctgttttt tgtttagaaa
     9061 agtgctgtca gccccaatat cctctttaaa atgatgaatt tcattcttta ttagtgttgc
     9121 aatcatttgc tgaatttctt gagtttgttc ttctggcaat tgtactagca tatattattc
     9181 tcctcttaaa aataaaaaag aagagtaaaa tactctcctg ctgttaaaaa gattaattct
     9241 tcttatttat tattttgttg aaaaaaacta gcaaagcgac cccgaccact gtcaattgtt
     9301 tgcccttatt acgacatgca tcacaaattg gtattgtttt aggtgatgag attgtttttt
     9361 tacaagtttt acacttcttc gtttttagtg tcattttttt ctccgtttcg atttttgctg
     9421 tttcggtatt gcttaagtta acgttactat cttggtggaa ttcaattaat ttagtattaa
     9481 tattaataaa taagtcccta ttgttttttg agtagctgta atgattatga attaattcta
     9541 acaaacttac ttttgggata ctattattct ttatccattt taattctttt acataaagaa
     9601 gtttttttgc tagttctttc aaataatttg ttttgtatgg aatattttgt ttagaaacta
     9661 attccatcga accttgaaaa gatagtagcc gatcatgggc tatcccctca ttatttagtg
     9721 ttaaatcgat ataaatttgc ataccaacaa ttttagtcat aatttctatg tcttgaagta
     9781 aaaaatcagc atgtgtttgt aaagaggctt gacggtatgt tggttggctg attttcttaa
     9841 taatttcatc tctatttgaa attatatcag atttaatagc acttactgat tcttcaaata
     9901 atgtatttgc atcctttagt gacttaactt tttctctgaa atctttgcta ttgttggctt
     9961 ctataacttt tgtacgagct gaataaaatg gagctagtat actattattt ctttcccatc
    10021 taatctgata atcttgactt tctttgatat ctaacagtaa gttatagatt tgtttaagtt
    10081 gagcttgagc gattagatca ctaggaactt gattttcgtt gttattagtc attttcctta
    10141 atgtcaaatc ttcaacacga ttcttctgat cggttgtgtc tacaattaca gccctaagat
    10201 ttccttctac ttttctagat tccccaattt tataagcgcc ctcttgaagt ttcgctttgg
    10261 tgtcaggaga tagactgtca aagtcaacct catatagagt agcattattg aaatctagta
    10321 ttttagtgtt aggattaaga tattggtttg aaaagttgaa tggaggggtt cctttagtat
    10381 caaataagtt taagatatca aatgggaaac tttctttaat catgttgggg agagcttgtt
    10441 caaaaggact acttatttca aagatatctg ttgttttgat atctgtctca tttttaaata
    10501 aatcaaaaga ttgtaagttt ttttgattga ttcttctttt tgcttttctg atttagcaac
    10561 ttcgttcatt agatcaccta gtcatttttg tattaattat aacatttagt attgatttta
    10621 aacgtatcta aattaataat actaaaaatt aatattatta aaaccatcat cagtgtccaa
    10681 tgacataagt aatttgtttt gctgtttctg catcaaaagt gcggtagcta acgactccta
    10741 gtcctttgat atttgattca gagatgagga tggagccatc tgatttgact tgttccacaa
    10801 aggcgatgtg gccataagtt ggatctgctc cagcttgccc tgggctaaaa gatagagcgg
    10861 agtgttcggt tggggtatga gttgtctgat accctggggc attcatccat tggccaccat
    10921 ttcccatata ctttccgaag ctaacaccga cttcttttcc tcggttatag acaaaccagg
    10981 tacattgtcc ccaaggataa gacagtcctg tgtggcttga ggtattgatt tctttggtga
    11041 ggctatagcc ttgtgggaca tcccctgttg tgacaccgcc tccgtctctg gtttttcctt
    11101 tcgtctgttc aggggctttt ggtgtacctc catgctcatc gatataggta tcgagttttt
    11161 gcatggtttc agcacgccct ttcctagagc cagaggtatc ggtgaagtag acgccaccat
    11221 ctgttgacgt gttgagagaa ccactcgcaa atttttgcgc tttgtcatct tggactttta
    11281 aggtttcatt tttattgcca atgatggtct gctttgtgag tccaacaacg gctacttcat
    11341 cgttaaaatt attggcattt tctggattag agtcaaatgc ggttctgttg caaagtttta
    11401 aataaagaat aaaatccctt acggtatcta tgatttaagc tgggattccc aataatacct
    11461 tgatttcagt acagaccgaa aacccgaaga gagtgccttc ttttcgagtt ttcttatata
    11521 atcctcggat ggcttccatg cctttaatcg tggtagaggc agtgcgtaaa cttcgataga
    11581 atttattgtg tctctttact ggacgatggt cttgttcaat caaattattc aggtatttaa
    11641 tggtacaatg ttctgtccct tgataaaagc cccgtattct cttagtttct taaaggcact
    11701 tgtaatagag ggggctttat ctgtgactac aaccttcggt tcatcaaact gcttaactaa
    11761 ccgctcaaga aaagcatagg ctgtttgtgt gtcccgtttt ttacgtaacc aaatatccaa
    11821 ggttaaacca tctgcatcga tggctcgata caaataatgc cattttcctt taattttgat
    11881 gtatatttca tccattttcc atgaataaaa ggatttttta tttttctttt tccaaatttg
    11941 atagagtagt ttgccatatt cttgcaccca acgataaatc gtcgtatgag aaacgttaat
    12001 gccacgatca tataagattt cttgaacttc acgatagcta aggttataac gaagataata
    12061 gcccacggtt acaataatca catcctgctg aaattgcttt cctttaaaat gatttatcgt
    12121 cattcctcct gctatctttt tctattattc tacctgattt gatagtagat ttaaaacttt
    12181 gcaacagaac cgatgtaacc gtttattaat cttttttatc atctatggat aacatttttt
    12241 tgttacacta ggagtatgaa aaaggagata tgatgaaaca gagccaagct aaaaagcatg
    12301 acaatacgat gactaataag attttgatga ggttgattgc tcttgtctta ggtttgcttt
    12361 ttcttgaaat tttgattatt catagtaaaa atgagcagca aaagagtgtt tcaaatcaag
    12421 tacagacagc acgtatcatg gctaatgggg acttgcttta tcatgacggt ctctatatga
    12481 gtgccttgca ggcagatggc agttatgatt ttactgaaaa ttttacatat gtgaagccat
    12541 ggttaaagca ggctgatttg gtcttgggtg attttgaggg aactatcaat cctgattatc
    12601 ctttgtcagg ctaccctctg tttaatgctc ctcaatcagt gacggcagct attagtgatg
    12661 ccggctatga tgttatggat ttggcccata atcatatttt ggactctggt ttagagggag
    12721 cttttacaac agccgatgca tttaaagagg tgggcattga ccctgttggt gtttatgaaa
    12781 atcctgtgcg tgataaggcg cctctgttta tcaagaatgt taatggcatc aaggtggcaa
    12841 tactttctta tgcctatggt ttcaatggct tggagtcaaa tctgaccgaa aaagagattg
    12901 cgaatcattt gtcgaatctt gatgaaaaac ggatgaaagt agagattgag cgtgctgaaa
    12961 aagaggctga cgttacggtt attatgccac agatgggcgt ggaatatcgt ttggaaccga
    13021 cagatgaaca ggtaaagctt taccataaga tgattgattg gggtgctgat attatctttg
    13081 ggggccaccc tcatgtggtt gagccgtctg aagtggttaa aaaggatgga cagcaaaaac
    13141 tcattattta ctcaatgggg aatttcatct ctaaccagcg catagagact atggatggtg
    13201 tggatagtgc agcatggaca gagaggggcg tcttaatgga tgtcactctt gagaaaaaga
    13261 attgtcaaac cacgattaag acagctcaag cgcatccaac ctgggttaac cgcacaccca
    13321 agggaacaat ttcgccagag ggatatcctt tatatactta tcaaacctat attttagagg
    13381 atttcattaa aggtggaaaa tacagaaata aactagatga agaaactaaa gagcgtatag
    13441 atactgccta taaagaaatg aatgctcatg ttaatctaaa atggaaataa agctaagata
    13501 tcgctaaaat ttggcgatat ttttctttat cgacaagtta ccaacagact tatccacagg
    13561 tgtggataag tctgttctca gtgttaaacc ttgatttttc aaggttttat tagaattgta
    13621 ttgttttact tgttaacaag tttatccaca agttgttgaa ttgatagaga ctgaatttta
    13681 taaacgatac tggttaaatg ttgtagaaac attcgttttt ttcaataaaa aaggtgtaat
    13741 ttctataaaa aatagcgttt ttaatcaaaa tatgctaaaa ttatataaaa taaaatgatg
    13801 gaggcttctc atgaaagcga ttattacagt tgtaggtaag gataaagcgg gtattgttgc
    13861 aggtgttgcg actaagatcg cagaacttgg tttgaatatt gatgatatca ctcaaacaat
    13921 ccttgatgaa ttctttacca tgatggcggt tgtatcatcg gaagataaga aagattttac
    13981 acacctacgt gctgaattag aagcttttgg tgaatcatta aacgtcaaaa tcaatatcca
    14041 aagctcagcg atttttgatg ctatgcacaa cttataagat aggggtagtt gaaaatggat
    14101 attaaacagg ttacagaaac cattgctatg attgaggagc agaactttga tgttcgtact
    14161 atcaccatgg gaatttcact tctagactgt atcgattcag atattgataa ggcagcagaa
    14221 aaggtataca acaagattgt ttctaaggct aagaacttgg tagctgttgg tgacgaaatt
    14281 gcggctgaac ttggtattcc gattgttaat aaacgtgttt ctgttactcc gatttcaatt
    14341 atcggtgcgg cgacagatgc gacagattat gtaccgtttg ctagggcact agaccgtgca
    14401 gctaaggaaa ttggcattaa ctttattggt ggtttctctg cattagttca aaagggctac
    14461 caaaaaggtg atgagattct tattgattct atcccacgtg cgcttgctga gactgatttt
    14521 gtctgctcat ctgttaatat tggttcaaca aaaactggta ttaacatgac agcggtacgt
    14581 gatatgggac gtatcattaa agaggcttct gaggcagatc caatgggtcc aggtaaattg
    14641 gttgtctttg ctaatgcggt tgaagataat ccatttatgg caggtgcctt ccacggtgtt
    14701 ggtgaggctg acgttgtaat caatgttggg gtttcaggtc ctggtgttgt gcaacgtgct
    14761 gttgagaagg tttcaggtga aagttttgat gttttagctg aaacagttaa gaaaactgcc
    14821 tttaaaatca cacgtgtagg gcagttggtt ggtcaaatgg ctagcgaacg tctaggtgtc
    14881 gagtttggta ttgtagactt gtctcttgca ccaactccag cagtaggtga ttcggtagct
    14941 cgtgtacttg aagccatggg gcttgaagtt gttggtacgc atggtactac tgcggctcta
    15001 gctcttctta atgaccaagt taaaaaaggt ggtatcatgg catgtaacca ggtcggtggt
    15061 ttgtcaggtg cctttatccc agtttctgaa gatgaaggaa tgattgcagc agttcaatct
    15121 gggcatatca accttgaaaa attggaagcc atgacggcta tctgttctgt tggtctagac
    15181 atgattgcca ttcctgctga tacgccagat acaacaattg cggccatgat tgccgatgaa
    15241 gcggctattg gtgtcattaa tcagaaaaca acagctgttc gtattattcc ttatggtaag
    15301 gaagg
//
