LOCUS       gnlProkkaMMGLMOIF_73   14140 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MMGLMOIF_73.
ACCESSION   gnlProkkaMMGLMOIF_73
VERSION     gnlProkkaMMGLMOIF_73
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:04:05
            Original ID  :: gnl|Prokka|MMGLMOIF_73
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14140
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..14140
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[908:4140]"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      909..4140
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="5000"
                     /detection_rule="(PF04055 and TIGR01716)"
                     /neighbourhood="10000"
                     /product="RaS-RiPP"
                     /protocluster_number="1"
     cand_cluster    1..14140
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(PF04055 and TIGR01716)"
                     /kind="single"
                     /product="RaS-RiPP"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14140
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RaS-RiPP"
                     /region_number="1"
                     /rules="(PF04055 and TIGR01716)"
                     /tool="antismash"
     CDS             complement(169..912)
                     /locus_tag="ctg56_1"
                     /transl_table=11
                     /translation="MKILSIIYDGGSRIPGARFAPTKYYQEAMLYDRKDSDIITINLGN
                     QDLFSIDLESLSRTIAESKVQIALGGDHSVTYLLAKATVREGAYLIVLDAHLDYFKDFE
                     SVVKNWNFLSFLTDIFEKIIIIGERNFEFPSSFDNKIIILSMEEYWLNKSRVLKKLDSY
                     IDESKDIYLSIDIDVLDPSVFDSVSYPIIGGFQMNDFLGIISKILCSDKVYFCDIVEYN
                     PMVGSDNAHIFYQMIQFVKSKLRRI"
     CDS             complement(909..2126)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: PF04055"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Streptide_RRE"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR04085"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) SPASM"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_2"
                     /sec_met_domain="Streptide_RRE (E-value: 1.5e-16, bitscore:
                     52.4, seeds: 8, tool: rule-based-clusters)"
                     /sec_met_domain="PF04055 (E-value: 6.7e-22, bitscore: 70.3,
                     seeds: 518, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_12 (E-value: 2.2e-10, bitscore: 32.7,
                     seeds: 84, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR04085 (E-value: 7.1e-12, bitscore:
                     37.3, seeds: 281, tool: rule-based-clusters)"
                     /sec_met_domain="SPASM (E-value: 1.9e-09, bitscore: 29.7,
                     seeds: 166, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTSNVYSIFFNWYNKQGILRNNRNNKLFSLNLATFLALKFMYQFS
                     LKKFSDSKSQVIKNVIDFLNNNEISLSKTNTKIVEFSTKIPLKVIQIEVTNKCNLRCMH
                     CYLPDYSKELDRKKISSIVYEAKQLGVMDVDFTGGEPLLLQGLSEIIEEVLKEGMCTTI
                     FTNAVYIPEDFKILIQRYDGIRLKVSLDGWNETIHDSIRGRGTFKRTIKNIEYFRSLGV
                     PVTVNVVLNNKNISGVKYFLELFDRLDVKYAFDRFLPFERNNRLSISDEEFNNAILCIP
                     NIQANCNNISESTFESFYCGAGNSYVFINSSGDVGFCPTLSSTKFCGGNINEKTLNDIW
                     INSKFFNHIRNVRCKYYNECPANYVCQGGCRSRAQFFGGSIGSPDIQECKLAYNLTGIK
                     PKSMSL"
     CDS             complement(2209..2361)
                     /locus_tag="ctg56_3"
                     /transl_table=11
                     /translation="MQVSDAIAQIELAEEEEVVSSGLSIDIMEIKPSVATELIDGLKGR
                     CPPSV"
     CDS             complement(2621..2788)
                     /locus_tag="ctg56_4"
                     /transl_table=11
                     /translation="MPVFSPSLHVSEERLKYEIEYQNNFKNTLSEYYRTKTADGTTEFK
                     EYEKWYIYII"
     CDS             complement(2837..3223)
                     /locus_tag="ctg56_5"
                     /transl_table=11
                     /translation="MRIIKFPEQISEDIIHYTFLDDIISYNCEKCRGSCCHVNNSLLLD
                     AKTASFLKRTYLKDFIVSDDSVSLLSCGKKCWFHSELGCTINDLGLNKPLTCELYPFHI
                     KKIQNFYIVSFTPCPTFQLNLGEG"
     CDS             complement(3283..4140)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RaS-RiPP: TIGR01716"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg56_6"
                     /sec_met_domain="TIGR01716 (E-value: 1.9e-46, bitscore:
                     150.1, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKDYGKLFKKFRESRGLVLKDIAKLGVSVSHISRFERENTDLTIG
                     KFMSALNAINMPIDEFMYAANDFQRDEFNEILEKISLFVSARNVSGMEKLLISQVEKIE
                     KRETFYTLNTILIKIRLQDLSDKSYYDESDIQYLSNYLFSVEYWGCYELLLFANTVDVL
                     NHQTMMLLSREMCKRSEFYKDLPNYRRLHSTMLLNCYIISIERDEYIDALYFEKQLNHS
                     CFTETEIYEKLVFHYSKNLYELKKNRSNKAILEMKKCIAAMKLANSENLAIKFENHLSG
                     VLKM"
     CDS             4743..5096
                     /locus_tag="ctg56_7"
                     /transl_table=11
                     /translation="MKQKRHKLAKERKNVSGEPGELIAKRYFMYLKRFQAVGFLNPLQI
                     RLIAETFAHIPTSYFFDENRNDWWNYYQMEVDYCEILNFQHKKKHLITIRCLCIFYLSK
                     LSIKIMLQAFKNL"
     CDS             complement(5031..5372)
                     /locus_tag="ctg56_8"
                     /transl_table=11
                     /translation="MDITNFIPSQRQAMLERFQQVEALGLGAVRIELKVANPVGIIYEC
                     YIMSGENYFSDQAVVSFRILYEKDLDRISLDVVDIPGRSSLSNYLQLLEIFEGLQHYLN
                     REFAKVKNT"
     CDS             complement(5778..7610)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1190:GTP-binding protein LepA (Score: 550.5; E-value:
                     8.6e-167)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_9"
                     /transl_table=11
                     /translation="MPNIEELKQRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSRE
                     MQAQLLDSMDLERERGITIKLNAIELNYKAKDGETYIFHLIDTPGHVDFTYEVSRSLAA
                     CEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGL
                     DASEAVLASAKAGIGIEEILEQIVEKVPAPQGDVEAPLQALIFDSVYDAYRGVILQVRV
                     VNGMVKTGDKIQMMSNGKTFDVTEVGIFTPKAVGRDYLATGDVGYVAASIKTVADTRVG
                     DTVTLADNPAAEPLHGYKQMNPMVFAGLYPIESNKYNDLREALEKLQLNDASLQFEPET
                     SQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVNTTDGEMLEVSNPSE
                     FPDPTRIDTIEEPYVKAQIMVPQEYVGAVMELAQRKRGDFETMEYIDDNRVNVIYQIPL
                     AEIVFDFFDKLKSSTRGYASFDYELSEYRRSQLVKMDILLNGDKVDALSFIVHREFAYE
                     RGKLIVDKLKKIIPRQQFEVPIQAAIGQKIVARTDIKALRKNVLAKCYGGDVSRKRKLL
                     EKQKAGKKRMKAIGSVEVPQEAFLSVLSMDEDEK"
     CDS             complement(7998..8144)
                     /locus_tag="ctg56_10"
                     /transl_table=11
                     /translation="MQTFAKDITLKRLSEPEDVAAAVSFLAGPDSNYITGQTIIVDGGM
                     QFH"
     CDS             complement(8420..8803)
                     /NRPS_PKS="Domain: PKS_KR (17-125). E-value: 2.2e-10.
                     Score: 32.6. Matches aSDomain:
                     nrpspksdomains_ctg56_11_PKS_KR.1"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     108.4; E-value: 7e-33)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_11"
                     /transl_table=11
                     /translation="MVKLVTTIGRGGFRMSKVAIVTGAGQGIGFAISKRLVEDGVKVGV
                     LDYDAETAEKAVAELSEDKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVAPT
                     KSLDTITEEQFQRTFNINIGGVI"
     aSDomain        complement(8429..8752)
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg56_11_PKS_KR.1"
                     /evalue="2.20E-10"
                     /label="ctg56_11_PKS_KR.1"
                     /locus_tag="ctg56_11"
                     /protein_end="125"
                     /protein_start="17"
                     /score="32.6"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C1"
                     /tool="antismash"
                     /translation="VAIVTGAGQGIGFAISKRLVEDGVKVGVLDYDAETAEKAVAELSE
                     DKAFSVVADVSKQAEVAAAFQKVVDHFGDLNVVVNNAGVAPTKSLDTITEEQFQRTFNI
                     NIGG"
     CDS_motif       complement(8678..8746)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg56_11_0001"
                     /evalue="1.40E-03"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg56_11"
                     /protein_end="42"
                     /protein_start="19"
                     /score="11.3"
                     /tool="antismash"
                     /translation="IVTGAGQGIGFAISKRLVEDGVK"
     CDS             complement(8972..9265)
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1163:rhodanese domain-containing protein (Score: 60.2;
                     E-value: 2.8e-18)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg56_12"
                     /transl_table=11
                     /translation="MDIAQIQSELAQDGLLIDVRTPEEYAEGHVKDALLIPHTQFFTAD
                     IPAKKDASIYLYCKMGSRAEFAAGVLKERGYTKVTTLGGLGDMEALGFKFEK"
     CDS             complement(9267..9695)
                     /locus_tag="ctg56_13"
                     /transl_table=11
                     /translation="MKVGNMQKTFFIIKPDAVKRHLIGQVLDRIERRGFVIERMEMLML
                     DEERLKEHYAQLADKPFFPSISEFMMSGPAVIGIMSGPGVIKSWRDMMGATNPGDAAPG
                     TIRGDFATAPDGDMIPNIVHGSDSEESAAREIKIWFGE"
     CDS             10006..10797
                     /locus_tag="ctg56_14"
                     /transl_table=11
                     /translation="MADQKANGIDILTDGKFGRSMWHLDFVWGLKGIERYIAEHGYTFK
                     DHDGGQYETRKDIGIRITEPLSGKNHHYLDIYKLVKAEAGDEDTKQTIWGPAHAYTELA
                     IFDRLAVPGQVYETNEELKKGLINAYKEFLDEYKAVGGKIVQFDDCLWELFDPSNPTSF
                     YSDGNGDLAELADEFVAINNEVVDYTHELGLTVWTHNCRGNYEIRSASEGTYEDIAKKF
                     LAEQHYDRFFLEWDSDTAGDIKALEALKDSKAEVVFGLLSS"
     CDS             complement(11062..12405)
                     /locus_tag="ctg56_15"
                     /transl_table=11
                     /translation="MSQSKADYINVIGAGLAGSEAAYQIAKRGIPVKLYEMRGVKATPQ
                     HKTTNFAELVCSNSFRGDSLTNAVGLLKEEMRRLDSIIMRNGEAHRVPAGGAMAVDREG
                     YAEAVTAEIESHPLIEVIRKEITEIPDDAITVIASGPLTSDALAEKIHELNGGDGFYFY
                     DAAAPIVDKATIDMNKVYLKSRYDKGEAAYLNCPMTKEEFMAFYEALTTAEEAPLNSFE
                     KEKYFEGCMPIEVMAKRGIKTMLYGPMKPVGLEYPEDYMGPRDGDFKTPYAVVQLRQDN
                     AAGSLYNIVGFQTHLKWGEQKRVFQMIPGLENAEFVRYGVMHRNSYMDSPNLLKQTFQS
                     KSNPNLFFAGQMTGVEGYVESAASGLVAGINAARLFKGEDEVIFPHTTAIGSLPYYVTH
                     AESKHFQPMNVNFGIIKELEGPRIRDKKERYEKIAERALKDLQTFIDA"
     CDS             complement(12506..13900)
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 125.4; E-value: 5.9e-38)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg56_16"
                     /transl_table=11
                     /translation="MALIKKREHSLRTILLSYVVSLTVLSVISSLLILYLFSLSFRFGV
                     VIPANQVESDLSAVRSDIETSKVFNPEILPDGTSYVFLTRDFKLKKSNMPVNLQEESLL
                     NYQFKNAHGGKYGYFQSFERSDGIVIVNYQLSPRYRNEWMNQHFPNADLMMIGSMFVSI
                     LIIFIILTFYYANKLSQQLKPILRVTEKISQQDLDFQTSQSTIKEFNQVLSGLDHMRIA
                     LRESLMENWKAEQDKQNQISALTHDLKTPLTVARGNAELLAMTSLDENQTDLLEHFQKG
                     IAQVDAYVKELSELNKMSLKKTLTLEEVPVKEFVEDIYDQTLSLAQTKQINVVFDKKEI
                     AKESIGNWDKSLLNRAIMNIVSNAVEHTPSGSQLLLTARVEEDEFKFICLDSGPGFSLE
                     SLENATQLFYQEDKSRQSRNHSGLGLTIANDIIRLHYGSLSLANDNGTGGAKVTIILPL
                     LNTDDS"
ORIGIN
        1 ataggaataa atctctttct agtaatgttt tgcaactcta ctataacgga tttattcctt
       61 tttgtgttta cacaacttat tttacactac cccatactct gagattaacg atgagaaacg
      121 attaaaataa atactcaatg ctgcatattt ttttattttc aatatttcct atatcctcct
      181 taattttgat ttaacaaatt gaatcatttg gtaaaaaatg tgagcattat cacttccaac
      241 catcggattg tactcaacta tatcacaaaa atatacctta tcagaacata aaattttgga
      301 aattattcca agaaaatcgt tcatttgaaa tcctccaata ataggatatg atactgaatc
      361 aaaaacagat ggatccaaaa catcaatgtc tattgataag taaatatctt ttgactcatc
      421 aatataacta tctaactttt tcaaaactct actcttattt aaccaatact cctccattga
      481 gaggatgatt attttattat caaatgaact aggaaactca aaattccttt ccccaatgat
      541 aattattttt tcaaaaatat cggttaaaaa acttaaaaaa ttccaatttt ttacaacact
      601 ttcaaagtct ttgaagtaat ctaaatgagc atctaaaaca attaaatatg ctccctctcg
      661 aacagtggcc tttgctaata gataagtaac tgaatgatct cctcctaaag caatctgaac
      721 tttagattca gcaatagttc gacttagact ttctaaatca atagaaaata aatcttgatt
      781 acctaaatta attgtaatta tatcagaatc tttcctatca tataacatcg cttcttgata
      841 atattttgtg ggagcaaatc tcgctcctgg aattctactt ccaccatcat aaataataga
      901 taatattttc ataaactcat tgactttggc ttaatcccag ttaaattata tgctaacttg
      961 cactcctgta tatcgggact cccaatagaa cctccgaaaa actgagctcg acttctacac
     1021 ccaccttgac aaacataatt tgcagggcat tcattataat acttacatcg tacatttcga
     1081 atatgattga agaacttcga attaatccaa atatcattta aagtcttttc attaatgtta
     1141 cctccacaaa atttagtgga ggataatgtc ggacaaaatc caacatcacc tgacgaattt
     1201 ataaacacat aagaattgcc agcaccacaa taaaatgatt caaatgtgga ttcggatata
     1261 ttattacaat ttgcttgaat attgggaata cacaaaatag cattattgaa ttcttcatca
     1321 ctaattgata gtcgattatt cctttcaaaa ggtaaaaacc tatcaaaagc atatttcaca
     1381 tctaatcgat caaacaactc caaaaaatac ttcactccac taatattctt gttattcaaa
     1441 acaacattaa cagtaacagg tactcctaaa ctcctaaaat attcaatatt cttaattgtt
     1501 ctcttaaatg tacctcttcc tctaattgaa tcatgtattg tttcattcca accatctaaa
     1561 ctaactttta gtcttatacc atcatatctt tgaatcaata ttttaaaatc ttcaggaata
     1621 tatacagcat ttgtaaaaat tgttgtacac attccctctt ttaatacttc ctcgataatt
     1681 tcacttaatc cctgtaataa taatggttcg cctccagtga aatcaacatc cattactcct
     1741 agctgcttag cttcatatac tatacttgaa attttctttc tatcgagctc ctttgaataa
     1801 tcaggtaaat aacaatgcat acatcttagg ttacatttgt tcgtgacctc aatctgtatc
     1861 acttttaatg gtattttcgt tgaaaattca acaattttag tgttggtctt agagagtgat
     1921 atttcattgt tatttagaaa atctataaca ttttttatta cctgactctt tgaatcagaa
     1981 aactttttca atgaaaattg gtacataaat tttaaagcta aaaatgtagc taaatttaat
     2041 gaaaatagtt tattattcct attattcctg agtattcctt gcttattgta ccaattaaaa
     2101 aaaatcgagt aaacattgct cgtcatatta attccctgca atcttccaaa aatattaata
     2161 taaaaaccaa aggattagaa atagactcta atcctacaat cagttctatt agacagacgg
     2221 tgggcaacga cctttgagtc catcaatcaa ctctgtagca acagaaggtt taatttccat
     2281 aatgtcaata gatagaccgc tagaaacaac ttcttcttct tctgctaatt caatttgtgc
     2341 aatagcatca ctaacttgca tcgtaatatc ctccattatt tatttaagaa tcaataagta
     2401 cccataacaa atcatagaaa tcattcttta tctataaaat ttagctgaaa atgctttgaa
     2461 attgtcttat taaactgatt tgcaataata aagtatatgt tatctgttcg tatatatgat
     2521 atttttttat aaacatcttc acaaactctc ttgtaaagat tccaaaattg atttgcttgt
     2581 gaacttgtat aagataaggg tatacttccc catctaaaat ctaaataata tatatatacc
     2641 atttttcata ttctttaaac tctgtagtgc catcggcagt ctttgttcga taatactctg
     2701 ataaagtgtt tttaaaattg ttttgatact caatctcata tttcagcctt tcctctgaaa
     2761 catgcaaaga cggactaaaa actggcaccc cagttttaat atatcgtaaa actacatcct
     2821 ctatatcctt gtacctctac ccctcaccaa ggttcagttg aaatgtcgga caaggagtaa
     2881 aagaaacaat atagaagttc tgaattttct taatatgaaa aggatataat tcacaagtta
     2941 atggcttgtt caagcctaaa tcatttatcg tacaacccaa ttcagaatga aaccagcact
     3001 ttttaccaca actcaacaat gaaacactat catcactaac aataaaatct ttaagatacg
     3061 tgcgttttag aaaacttgct gtctttgcat caagtaataa agaattattc acatgacaac
     3121 aagatcctct acacttttca caattataag agataatatc atctagaaac gtataatgaa
     3181 tgatatcttc tgaaatctgt tcaggaaatt taataattct catatcaata atatatcatt
     3241 taattttgac actgataatt tataccatat acacaaatcc aactacattt ttaacactcc
     3301 agataaatga ttttcaaatt ttatagctaa attctcacta ttagccagct tcattgcagc
     3361 aatacacttc ttcatttcta gaatagcttt attgctccta ttcttcttta attcatataa
     3421 attttttgaa taatgaaaca ctaatttctc gtaaatctca gtttccgtaa aacaactatg
     3481 atttaactgt ttttcaaaat acaacgcatc aatatactca tctctttcaa tacttatgat
     3541 ataacaattt aatagcattg ttgagtgtaa ccttcggtag tttggtaaat ccttgtaaaa
     3601 ttctgaacgt ttacacattt ctcttgataa aagcatcatt gtttgatgat tcaatacatc
     3661 tacagtattc gcaaataaca gtagttcgta acaaccccaa tattctacag agaataggta
     3721 gtttgataaa tattggatat cagattcatc atagtaactt ttgtctgata agtcctgtaa
     3781 acgaattttt attaaaatag tatttagagt ataaaaagtc tcacgctttt cgattttttc
     3841 tacttgagag attaataact tttccatacc tgacacgttc cttgctgaaa caaataaact
     3901 aatcttttct aagatttcat taaactcatc tctctgaaag tcgtttgctg catacataaa
     3961 ctcatcaata ggcatattta tcgcatttaa agctgacata aacttaccaa ttgtcaaatc
     4021 tgtattttca cgttcaaagc gggaaatatg agatactgat acgcctaact ttgcgatatc
     4081 ttttaagact aatcccctag actctctaaa tttcttaaat aattttccat aatctttcat
     4141 aaaaagcacc tcttttgcat atacgagaat ttcccagata aacttaaaag tattatatca
     4201 tatagtgaga taggaggtta atttctatga ataaagaaag ttttttagct atcttacttc
     4261 taatttttga aagcattatt gtaattgctg ttggctaaac aaatagaaaa taaagacacc
     4321 acaaaagtta gactttcgat gtctaacttt tgtggtgtag ttaaggtatg atgttgttct
     4381 ctaataaggg tataatataa aaaagactct atgatttctg tagtaggtaa aaccactata
     4441 gagattatag agctttttga gtgtatacaa aaactagttc tttattggaa caaagtcaac
     4501 aactaatcta gtattggttg cagcggcaat ttcttccaat gttttatatg ttggattagt
     4561 ggtgccattc tctatacgtc cgatactagc ctgacttttt cccatacgat cagcaagttc
     4621 ttgctgagtt aaattgatat tctctcttaa ttgtttaatt ttatgcgata gctttataca
     4681 ctcgatttca ttgttatagt gctgtagaat ttcaggttcc tttttactcc tttctgccaa
     4741 gtatgaagca aaaaaggcat aaactagcca aagaacgtaa gaatgtatca ggtgagccag
     4801 gagaactaat cgctaaacga tattttatgt atttaaagcg gttccaagca gttggttttt
     4861 tgaacccttt gcaaattcgg ttaattgctg agacgtttgc acatattcct actagttact
     4921 tcttcgacga aaatcgtaac gattggtgga attattatca aatggaggtt gactattgtg
     4981 aaattttgaa cttccagcac aaaaagaaac acctgattac aatcagatgt ttatgtattt
     5041 tttaccttag caaactctcg attaagataa tgttgcaagc cttcaaaaat ctctagtaac
     5101 tggagataat tagacaaact tgagcgacca gggatatcta ccacatccaa agaaatgcgg
     5161 tccaagtcct tttcgtaaag aatacggaag gataccactg cttgatcaga aaaataattc
     5221 tctcctgaca taatgtagca ctcataaatg atgccaacag gattcgcaac cttcaactca
     5281 atacgaactg cgcctaagcc caaggcctcc acttgctgaa aacgttccaa catagcctgt
     5341 cgctgactag gaataaaatt tgtgatatcc atagtggccc tcccgacttt ccttttgtat
     5401 attatagcct aaagctgaga aaaatgcttg cgaagggatt cctgataaga ctacccccca
     5461 tgaatcctca tctagcttct ttatattctc taaagtctga ttttatagtg tttatcgtaa
     5521 tgtagtaagt gtgttctaca tgactaagta caacatattg ttgacgacta ccaaaaatct
     5581 cattggaagt taccttatct gcttttaggt cagtctataa ttctgctaca tgctttgtat
     5641 cgccattccc taaaaagaaa agtatttagt atgatcgtag cataaatcct tccacacttt
     5701 gagaaggtaa attttaaaat cctctttatc ataacttttt actaaaatag ccagaacatc
     5761 acattctact atcattctta tttctcatct tcgtccattg aaagcacaga caagaaggct
     5821 tcttgtggta cctccaccga accaatggct ttcatacgtt tcttaccagc tttttgtttt
     5881 tcgaggagtt tacgtttacg tgaaacgtca ccaccgtaac atttagccaa gacgttttta
     5941 cgaagagctt tgatatctgt acgggcaaca attttttgac caatagccgc ttggatagga
     6001 acttcaaatt gttgacgtgg aataattttc ttaagtttat caacgataag ttttccacgt
     6061 tcgtaggcaa attctctatg gacaataaag ctaagggcat cgaccttatc accattaagg
     6121 agaatatcca ttttcaccaa ttgtgaacga cggtactctg acaattcata gtcaaaactt
     6181 gcataaccac gagttgatga cttcaattta tcaaagaagt caaagacgat ttcagcaagt
     6241 ggaatttgat agataacgtt aacacgatta tcatcaatat attccatggt ttcaaaatca
     6301 ccacgtttac gttgcgccaa ctccataaca gcaccaacat actcttgagg aaccataatt
     6361 tgagctttga cataaggctc ttcaatggta tcaatacgtg taggatctgg aaattcagat
     6421 gggttggaca cttcaagcat ttcaccgtca gtagtgttaa catggtaaac tactgatggt
     6481 gcagtcatga tgagatcgat gttaaactca cgttccaaac gctcttggat aacatccatg
     6541 tgaagaaggc ccaagaaacc acaacggaaa ccaaaaccaa gggcttgaga cgtttcaggc
     6601 tcaaattgaa gactggcatc attcaattgg agcttttcaa gagcctcacg caagtcgtta
     6661 tatttatttg actcaattgg ataaagacca gcaaagacca ttgggttcat ttgcttataa
     6721 ccatgaagtg gttctgcggc tggattatcc gcaagtgtca ctgtatcacc gacacgagta
     6781 tccgcaactg tcttaattga agctgctaca taaccaacat ctccagtcgc aaggtagtca
     6841 cggccaacag ctttaggagt gaaaatacca acctcagtaa cgtcaaaggt cttgccatta
     6901 gacatcattt gaatcttatc gcccgtttta accattccgt taaccacacg cacttggagt
     6961 atgacgccac gatacgcatc ataaacagag tcaaagataa gggcttggag aggtgcttcc
     7021 acatcacctt ggggcgcagg aactttctca acaatttgtt cgagaatctc ttcgatacca
     7081 atgccagcct tagctgatgc aagcacagct tccgaggcat ctaatccgat aacatcttca
     7141 atctctgtac gtacacgctc aggatctgcc gctggaaggt cgattttatt gataactggt
     7201 aagatttcca agtcattatc aagtgccaag taaacattgg caagtgtttg tgcttcaatc
     7261 ccttgagctg catctaccac caagatagca ccctcacagg cggcaaggga acgtgacacc
     7321 tcataagtaa agtccacatg tcccggtgtg tcgataaggt ggaaaatata agtctcgccg
     7381 tctttagctt tgtagttaag ctcaatggca ttcagtttga tagtgatacc acgttcgcgc
     7441 tcaagatcca tactatcaag gagttgtgcc tgcatctcac gacttgatac agtctcagtc
     7501 ttttccaaga tacggtcagc aagcgttgat ttaccatggt caatatgagc aataatcgag
     7561 aagttgcgaa tcttctcctg tctttgtttt aattcttcaa tatttggcat tttattcttt
     7621 cctaattctt acttgtgatt gttaaaaaac gaaccgtcac ctcctattat acaaaaaaga
     7681 caggcatttg cctatctcta atatctgctt tatgactgca tttagtcctt cttatttctt
     7741 aaaattatca ttgtagtgct tattaataat agctgaacgc ttgttctcta ttgaactact
     7801 tgaaaatgga gctaaaccaa aggctagtac aataattccc aatagaataa gactaaaaaa
     7861 tgggtgctca gcaatatagt gtaagatgtc tgatatggga atccaccttt aaaaacataa
     7921 ttatttataa ctatattatc agaaacatta tgttttatca agcaaaaaaa gagagccatt
     7981 cgctctccct tttaacctta atggaattgc ataccaccat caacgatgat tgtttgacct
     8041 gtgatgtagt ttgagtcagg tccagctagg aagctaactg ctgctgcaac atcttcaggt
     8101 tctgacaaac gtttgagggt aatatcttta gcaaaagttt gcatacccca ctcatcatct
     8161 ttaccagcat tttaccaact tcgtgggcaa tgtcaaacat cattggagtc ttaacgatac
     8221 ctggtgcata agcatttaca gttatacctg aatcagctaa gtcacgcgcc aaagtttgag
     8281 taataccacg aactacgaat ttagttccac catatacagt taagttagag ttccctacga
     8341 cacctgcttg taaagttgca ttgataattt taccaccatg accaagtgat ttaaattgtg
     8401 cttgggcagc ttgtgcacct cagataactc caccaatatt aatgttaaat gtacgttgaa
     8461 actgttcttc agtaatagtg tcaagggatt ttgttggtgc cacaccagca ttattaacaa
     8521 caacattcaa gtcgccaaag tgatcaacta ctttttggaa agctgctgct acctcagctt
     8581 gtttagacac atctgctaca acggaaaatg ccttgtcttc tgacaactca gcaactgctt
     8641 tttcagcagt ttcagcgtca tagtccaata ccccgacttt aacaccatct tcaaccaagc
     8701 gttttgaaat cgcaaaacca ataccttgac ctgcacctgt aacaatagca acttttgaca
     8761 tacgaaatcc tcctctacca attgtagtca caagcttaac cacaagccct atctcaattg
     8821 gaatatgcta agttaatcaa gttctggcaa agtcattttc ataggctttt tcttaactca
     8881 tttagaatct taccacttta tgaaagcgtt gttaataatt tgtcatgctt tttgaaagca
     8941 aataagatca ccactagtga ccttatgtgt attatttttc aaacttaaac cctagtgctt
     9001 ccatatcacc taggccacct aaggtggtaa ccttagtata tcctcgttct ttcagtactc
     9061 ctgcagcaaa ttcagcacga gatcccattt tacaatagag gtaaatggag gcgtcttttt
     9121 tagctggaat gtcagctgtg aaaaactgcg tgtgaggtat taataaagca tccttaacat
     9181 gaccttctgc gtactcttct ggagtcctga catcaattaa tagtccatcc tgagctaatt
     9241 ctgattgaat ctgtgctata tccatcctac tcaccaaacc aaatcttaat ttctcgagcc
     9301 gcagattctt ctgaatcaga gccatgaacg atatttggaa tcatgtcacc atctggtgct
     9361 gttgcaaagt ctccacgaat cgttccagga gcagcatccc caggattagt tgctcccatc
     9421 atatcacgcc atgacttaat aactcctggg ccggacataa taccaataac tgctggacca
     9481 ctcatcatga attcagaaat actagggaaa aaaggtttat cagccaattg ggcataatgt
     9541 tctttaagac gttcttcgtc aagcatcagc atctccatac gctcaataac gaagccacgt
     9601 cgctcaattc gatcaagcac ttgaccaatt agatgacgtt taacagcatc tggtttaata
     9661 ataaagaatg ttttttgcat attcccaacc ttcatcgttt tctttccatt ttatcataag
     9721 aagtatcatt ttgcagagct aaaccttgta tagtctaaaa ctatatacac agcaagaaat
     9781 taactatttt tcattagttc ccataagaaa taatatagat gtaaatagac atttcgaggt
     9841 aaatttaatg acaaaatcta aattccaatt agtcggttct cttcttcgtc ctgcggatct
     9901 ccgtaaatac aaggacgaaa tcgagcatcg tgacgacatc cagtatcctt tctatgatgc
     9961 ccttcctggt tatcaagaaa ctgaaactgc atctattaag cgaatgtggc tgaccaaaaa
    10021 gctaacggaa ttgacatcct taccgatggg aagtttggac gttctatgtg gcacttggac
    10081 tttgtctggg gactcaaagg tattgaacgc tacattgctg agcatggtta tacttttaaa
    10141 gaccatgatg gtggtcaata tgaaacacgt aaagatatcg gtattcgtat cactgagcct
    10201 ctatcaggta aaaaccacca ctacctagat atttacaaat tggttaaggc tgaagctggt
    10261 gatgaagata ccaaacaaac tatctgggga cctgctcatg cctacactga acttgctatc
    10321 tttgatcgat tggctgttcc tggacaagtc tatgaaacaa acgaagaact caaaaaaggt
    10381 ttgattaatg cctataaaga attcttggat gaatacaagg ctgttggtgg taaaatcgtt
    10441 caatttgacg actgcctctg ggaacttttt gacccatcaa accctacaag tttctactca
    10501 gacggcaatg gtgatttggc agaattggcc gatgaatttg ttgctatcaa taatgaggtt
    10561 gttgactata ctcacgaact tggtttaacg gtttggacac acaactgtcg tggtaattat
    10621 gaaatccgtt ctgcttctga aggaacttac gaagacatcg ctaagaaatt cttggcagag
    10681 caacactatg accgcttctt ccttgaatgg gatagcgata cagctggtga tatcaaagct
    10741 ctggaagccc ttaaagacag taaagctgaa gttgtatttg ggctattgtc ttcttaaacg
    10801 actgacctag atgacgaaga acgtgttctc gatttgcttg aaaaagcgag tcaaatcctt
    10861 ccaaaaaaac gtctcttccc ctttcaccaa tgtggtttcg cctcatgtga ctcaggtaat
    10921 gagctggcaa cacctcaaca atgggctaaa atcaaacaag gtcaagaaat cgctaagaaa
    10981 ttctttggct aatcgatatt tctattcgct cctctctaaa acgaaaagcc ttcactcttg
    11041 tgagggcttt ttatgttagc atcaagcatc tataaaagtt tgcaaatcct taagagctct
    11101 ttctgcgatt ttttcataac gctctttctt gtcacgaata cgtgggcctt ctaattcttt
    11161 gataatacca aagttaacat tcattggttg aaaatgtttg ctttcagcat gtgtcacata
    11221 atatggaagg ctaccgattg ctgttgtatg agggaaaata acttcatctt cacccttaaa
    11281 gagacgggct gcattgattc cagcaaccaa acctgaggca gctgattcaa cataaccttc
    11341 aacaccagtc atttgtccag caaagaacag attagggttt gattttgatt ggaaggtctg
    11401 tttaagcaag tttggcgaat ccatgtaaga gttacggtgc attaccccat aacgaacaaa
    11461 ttctgcattt tcaagacctg gaatcatttg gaagacacgt ttttgctctc cccatttgag
    11521 gtgggtttgg aaaccaacga tattgtagag gctaccagcc gcattgtcct gacgaagctg
    11581 aacaaccgca taaggtgtct tgaagtcacc atcacgtgga cccatataat cttcaggata
    11641 ctccaaacca actggtttca taggaccgta gagcattgtt ttaataccac gtttagccat
    11701 aacctcgata ggcatacacc cttcgaaata cttttctttt tcaaaagaat tcaaaggagc
    11761 ttcttcagct gtagtcaagg cctcatagaa ggccatgaac tcttccttgg tcattggaca
    11821 gtttagataa gctgcttcac ccttatcata gcgtgactta aggtaaacct tgttcatgtc
    11881 gatagttgct ttatcaacga ttggtgcagc ggcatcatag aaatagaacc cgtctccacc
    11941 gttaagctca tgaatctttt cagctaaagc atcagaagtt aggggacctg aagcaataac
    12001 tgtaatagca tcatcaggaa tttctgtgat ttctttacgg ataacttcaa ttaagggatg
    12061 actttcaatt tcagctgtca ctgcttctgc atagccctca cggtccaccg ccatggcacc
    12121 acctgctggc acacggtgag cttctccatt acgcataatg atagagtcca aacgacgcat
    12181 ttcttctttt agaagcccta cagcattggt caagctatct ccacggaaag agttagagca
    12241 aaccaattct gcaaaatttg ttgtcttatg ctgtggtgtt gctttgaccc cacgcatttc
    12301 ataaagtttt actggaatac cacgtttggc aatctgataa gccgcctcgg atccggccaa
    12361 accagctcca atcacgttaa tataatctgc ttttgattga gacatgacac taatacctct
    12421 tcggaaacaa gatgaaatcc tgctcccaca aatctttctt catttttact cttagtagta
    12481 tagcaaaaaa ctcctcatct ggcgactagg agtcatctgt atttaaaagg ggtaaaatga
    12541 tagtcacttt agcaccaccc gtgccattgt catttgcaag agaaagacta ccatagtgta
    12601 aacgaataat atcattagca atagtcagac caaggccact atgattgcga ctctgtctgc
    12661 ttttatcctc ttgataaaat agctgagtag cgttttcaag agattcaagg gaaaatccag
    12721 gaccagaatc aaggcatata aacttgaatt catcttcttc taccctagcg gtcaggagca
    12781 actgactgcc actgggtgta tgctctacgg catttgaaac aatattcata atagctcgat
    12841 tcaacaagga cttatcccaa ttgcctatgc tttctttcgc aatttccttc ttgtcaaata
    12901 ccacattgat ttgtttcgtt tgagctaatg acaaggtttg atcgtaaatg tcttcaacaa
    12961 attccttaac tggaacttct tcaagcgtca gggtcttctt caaactcatt ttgttgagtt
    13021 ctgacaactc ttttacataa gcatcaacct gtgcaatacc tttttgaaaa tgctctaaca
    13081 agtccgtttg attttcatcc aaggacgtca tagctaagag ttccgcattt ccacgagcaa
    13141 ctgttagggg cgtctttaag tcatgtgtta gggcagaaat ctgattttgt ttatcttgct
    13201 ctgccttcca attttccatc aaagactcac gaagtgctat acgcatatga tccaaaccac
    13261 ttaaaacctg attaaattcc ttaattgtag actgagaagt ttgaaaatcc aaatcttgtt
    13321 gggaaatttt ttcagtaacc cttaatatag gtttaagttg ctgactcaat ttatttgcat
    13381 aataaaaagt taaaataata aatattatta agatagatac aaacattgaa ccaatcatca
    13441 taagatcagc attgggaaaa tgttggttca tccactcatt acggtaccga ggtgatagtt
    13501 gataattgac aatgactatg ccatctgatc gttcaaaaga ctgaaaatag ccgtatttcc
    13561 caccgtgagc attcttgaat tggtaattta gtaaggattc ttcttgcaag ttaacaggca
    13621 tgttagactt tttaagctta aaatccctag ttaaaaagac ataactcgtg ccatcaggta
    13681 aaatctcggg attaaagacc ttagaagttt caatatcact tctcacagca gacaaatcac
    13741 tctcaacttg atttgctgga atcacaactc caaaacgaaa agacaagctg aacaaataca
    13801 aaataagaag actgctgatt acagagagaa ctgtaagact gacgacataa gataacaaga
    13861 ttgttcttag agagtgttct cgttttttta ttagtgccac ttgtaaccaa tcccccaaac
    13921 tgtttcaata ggattttgcc caacttcttt aagctttgca cggatattct tgatatgttc
    13981 agccactgct gccggactgc ctttatcctc atagccgtac aaatgcgtgt agatttgttc
    14041 ttttgaaaag acttggccct tattttcagc taaaaactgg caaataccat attccgactt
    14101 tgtcaaatct aacaactgat tctcaatata aagctcttga
//
