LOCUS       gnlProkkaDCPMIAPF_10   17147 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DCPMIAPF_10.
ACCESSION   gnlProkkaDCPMIAPF_10
VERSION     gnlProkkaDCPMIAPF_10
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 15:02:48
            Original ID  :: gnl|Prokka|DCPMIAPF_10
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 588896
            Orig. end    :: 606043
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..17147
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[10000:12160]"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10001..12160
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /neighbourhood="10000"
                     /product="lanthipeptide-class-iv"
                     /protocluster_number="1"
     cand_cluster    1..17147
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(cds(LANC_like and Pkinase) and not
                     micKC)"
                     /kind="single"
                     /product="lanthipeptide-class-iv"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..17147
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="lanthipeptide-class-iv"
                     /region_number="5"
                     /rules="(cds(LANC_like and Pkinase) and not micKC)"
                     /tool="antismash"
     CDS             complement(195..1334)
                     /gene_functions="other (smcogs) SMCOG1077:phage integrase
                     family protein (Score: 86.3; E-value: 5.4e-26)"
                     /gene_kind="other"
                     /locus_tag="ctg3_622"
                     /transl_table=11
                     /translation="MASVLYRKRGDSNLWTYEIRNEGKTVAHNSGFKTKKLAESEAEPI
                     LQELRLGKRISRDISLADLYQEWLELKILPSSRSEETKKKYLLRKNTIERLFGNKKVTQ
                     IRASEYQRIMNKYGQTVGRNFLGRLNTGIHQSIQMAIADKVLIDDFTQHVELFSSKEQQ
                     MTEEKYLHTEKDYLDLLLAVKRKFDYQRSIVPYIVYFLLKTGMRFGELVALTWNEVDFD
                     RGLLKTYRRYNTLSHKFVPPKNKTSIRMVPIDEECIKILRLLQTEQERANMELGIKNRY
                     RMIFQHFGYIHSVPDIASVNKALSVLLNELDIYPIITTKGARHTYGSYLWHKGFDLGVI
                     AKILGHRDISMLVEVYGHTLEEKIFEEFNQIRDIWKDCS"
     CDS             complement(1336..1524)
                     /locus_tag="ctg3_623"
                     /transl_table=11
                     /translation="MDNNLISNKELIEMGYRPHTANDIIHQARELLVSRGYTFYNRKRL
                     MVVPKSVVNEILGTEVA"
     CDS             complement(1536..2153)
                     /locus_tag="ctg3_624"
                     /transl_table=11
                     /translation="MYFARLNSLTVRLSRFDLAFDIFNRPEIVNLQHIKGGVTHKVFYG
                     RGGELETKYWGSSGSNVQVRLYDKNKEIIAHKHEEKLDLGVNPFWWRLEFQLRTKAIGE
                     DMVQDIMNRLDNFGFYKLEHIRVDQRAFTIIFLSNPELLSLAFPNLKSDSIKKKKTRVR
                     KLLREETNQFAEELKEVLIQNLPKLNTELQLLVGEFLTLENQ"
     CDS             complement(2157..2513)
                     /locus_tag="ctg3_625"
                     /transl_table=11
                     /translation="MLISIQDLRSIQERCEIGELVQRLDVSIDRLTVIWDTDTGPLRRI
                     FKNLKQAISTRVDSFEIHDNVRDDVFTLAKDFNEYDSINIIFFQLSTYGGEQLIRIDFN
                     PNTLKEFDGMKVWR"
     CDS             2922..3044
                     /locus_tag="ctg3_626"
                     /transl_table=11
                     /translation="MTFIIQNFGPNLARLRIEKGVSQTQLAEDLGIGKQSISDY"
     CDS             3075..3434
                     /locus_tag="ctg3_627"
                     /transl_table=11
                     /translation="MDKIAEYFNATPTQLFGTSKEIELEKSVLESNEYSDKVSEILKAV
                     KYIENFLETDGQYLEDLLYLTRGKQLYTEDGDELYTDPTSQKRTFHNQYEPGFIVARDK
                     SPLELLIENKELFDK"
     CDS             complement(3838..5379)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 150.2; E-value:
                     1.4e-45)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_628"
                     /transl_table=11
                     /translation="MLRSYVTKKHLTFYFLAIVITWLEAIITPALIQYIVASFTNRQLH
                     LLWQILLWGIGGNLVLVLGLAGKRYYYARLMTDFKVGIKRAIFRTFLYSRQIPDEEVLS
                     DLENDVQQLENSYIEPTVIIVSSLGFTVVSIAYALWTNFYLGLLFIIFYSVPVLCSGLG
                     SKRLDRIAEQKSLANQNYIARVNNMIAGVAPIRHYQGQNLFFKRFSKDLEQALQEEVSY
                     EKQRSLNSLFINSIDAFCSVAPIVIGGFMTYQNYLSAASFVGIYLVSHNIGYQFQELSY
                     FINTRKSAKSLCDKYQDLFGNKLATDSIFDQSVFPIQLEQVSVEKDGETILAPCDLTIH
                     AGEKIAIIGESGAGKTTLLNILYGEIHPSQGQIRYQGRELTSCQLYQAGAYILQSSHVF
                     DDLSVEENIALGQEIDQQRMDNILQETGLLSLKGKVPSNQTLSGGEKQRLEIARALYHK
                     RQFILADEVKANLDAKNQEKINQLLFSLPQAVVEVIHHYTKEDLKRYDKVIHLKK"
     CDS             complement(5361..6200)
                     /locus_tag="ctg3_629"
                     /transl_table=11
                     /translation="MKIETVTNGTVLNKRVKEMLVKFHPYLTISLDGPEIVHDRLRGRG
                     SHRKTLRFINYLKNIDYENFEIASTYTRLHQKNGLSREDIFQYFTDMDVHFNINDVFTK
                     NKVLIVKEMEKSLAERKQFIDKSIQHVINNNEKAFISPILYDVLISMIYKSTNRTFCDD
                     IDPSNTLTYDVDGSKKLCFRFWGTHNSPKAESFNNKDNFEKCKNCWCRGMCLECVANVI
                     DGYSSVISEDGEFLECSKPELMEYCIKQIIYLSKDREKLSRLVNNFRGVYTLCLGVM"
     CDS             complement(6190..6573)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_12"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_630"
                     /sec_met_domain="Fer4_12 (E-value: 1.6e-09, bitscore: 33.4,
                     seeds: 84, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIKTIETDIGTYYFDSVNFTLSLSPISKQSSPTLDSVEDGVLKKV
                     VINISNSCNLSCSYCYADGGNYGMDNRIMDLTTADNIIQEIASKGVTQINRLILFGGEP
                     FFKYRIIYIFYRKIIYIIKCSEN"
     CDS             complement(6630..6737)
                     /locus_tag="ctg3_631"
                     /transl_table=11
                     /translation="MEKLQVIDLEELLEFDQGYVINASCGPSHSCGGGR"
     CDS             complement(6815..7513)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_632"
                     /sec_met_domain="TIGR01716 (E-value: 2.2e-47, bitscore:
                     156.7, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MPIEEFVYAVRDFRRDDFNELLEKIRYLVSNRDIDGMKKLLISQM
                     EKKDKKEPFASFNTILIKIRLQDLSGETYVTDQEIVTISDYLFSAEYWGYYELLLFMNT
                     IDALNHNTMMILAKEMCHRLDFYRDIPNNRRLLATMLLNAYITCIERNEWMDALYFEKQ
                     LKYCNFSETEMYEKLVLHYANNLYDLKKNNNRHAVLEMRKCIAATKLVDSNQISIKFEN
                     YLQKVLDDMR"
     CDS             complement(7479..7673)
                     /locus_tag="ctg3_633"
                     /transl_table=11
                     /translation="MKYGKIFKKFRESRGLSLKNVAKSGLSSSHLSRFENDEADLTISN
                     FFSVRCNTYAYRRICLRCT"
     CDS             complement(8428..9996)
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 127; E-value: 1.5e-38)"
                     /gene_kind="transport"
                     /locus_tag="ctg3_634"
                     /transl_table=11
                     /translation="MKKYILKYKLLNLIHIILIGFSSAFLVGASVTLSIMLNKLVESDF
                     KGFLIWLGIEFGVYLLFLADTYLIRVNQTKLIQKMTLSLRDDYINSLTRKSFSEFKNKT
                     VGEHLSILNNDIKIIEESGFESFYSLVSTVFTTFFSIIALFSYDYRIVLLSILLTLILT
                     YLPRSFAHKMEKAMKRFSIGNETFISSLTDQLLGYDTLYYSNKKEMLSIKCGEVIKKFI
                     FEKIVFIKTSSLIEIIMSLFSIISQMLVLLLTGYLIILKQVSIGSISSVGQISGNIFNS
                     LTTFNQLQVSISSVNSIFEKFGAFEKSSHYRYIDKDIEEIKLTNVGYSFKDKEVFKNIN
                     CSFEKGKNYAIVGESGSGKSTLINIILGNNKQYSGSVKYNDVEISDIEESQLFKSVSYI
                     GNITHIYHDSLRNNLTLWDNKINESEIINILKQVNLIDLIPRLDDEVSMSFLSEGQKQR
                     LGIARAYLTKTNVIIMDESMANLDRDNAFLIENQLLNDPTRMYITVSHHLQEKLLDRFH
                     SIITL"
     CDS             complement(10001..12160)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: Pkinase"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     lanthipeptide-class-iv: LANC_like"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg3_635"
                     /sec_met_domain="Pkinase (E-value: 2.4e-13, bitscore: 45.3,
                     seeds: 54, tool: rule-based-clusters)"
                     /sec_met_domain="LANC_like (E-value: 3.4e-07, bitscore:
                     24.7, seeds: 47, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MEELITPSEKRIINRKKGEIYDYISYSNAFVPYQGWKIHISANLI
                     DYQSILDNVYHVCSIFQTPFKYINKISELFRILSKHVSQLEIGKFITIYPKNKETFLLL
                     LEELYDKIPKYTGVQILTDRSYKDSEIIFYRYGVMNARLINNERPKLKFNGTFYEDITE
                     PYYTCPPFVEDIIFNKVVDDYNIESLFHDRYQMESIIHKSGAGNVYIAIDTINEEKVII
                     KEARKKVYITEKILAIDLLLNEKCILKKLKGKVDIPNYIECFTIEGNLYLVEEFIDGQR
                     LDILKPEYNLLIKRNSSELGRYNKKVKKIISNLFLSLYKIHQEGIILEDISSSNILLTN
                     DDRVFFIDLETAYNKNDGIIVETTNECYPKNISQKNEQRDIVKMWYCIIDLLTNSTSLL
                     KYDNTGVSTLNLFYKMSLENNLPKSLRKKFINDFSIVDFKNTFIIKFIEMGLNIEKIVR
                     MQQDLTETILSHNTFEIYGKTILESIDNYKHISNMDLKFSSDPSFSSLYDNCNKSIDDL
                     IGIAILDNNFELFLNCNLDELLHNMSYYQKYYLLRLFNDTKICDRVYFIKVLNSIIKND
                     IKCIDGVKYIKSNEYFSPYLITGNSGLIIELIKFSKNNNTMKFDEWIRSLSEGISYTYA
                     KGTSLYYGLAGLGLANAWLYYYFKETSFLKTSIKICEHIFDFSIKQNTKTILIDPMSEE
                     IDYTYSKGMLGQLYFINELLNIIKE"
     CDS             complement(12245..13117)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) TIGR01716"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg3_636"
                     /sec_met_domain="TIGR01716 (E-value: 4e-30, bitscore:
                     100.3, seeds: 14, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIDTIDIGSLTKKIRLSKKLSLKDVAGDYLSVSFLSKFERGESEI
                     SLSRFLCILENLDVSIEEIYGILSKDNPTRTEELLARVSKAFQQNNIPALKKYYYEEIE
                     KFNSTHKKIFLYNSILIDSFLISITGKKMNKKHIEVISDYLFDVDQWGKRELVILGNSM
                     SAVPTNTLNLLIKEIIYKTTLFGNNEENKKIKIDLILNGISIFLERKELNYAKFYIDLF
                     DTLTIPEVYLYERVEYNILIGTYWILIGKIEVGKKKIELALESLKNLGAENLLLMRENE
                     YEELLNSII"
     CDS             complement(13278..13367)
                     /locus_tag="ctg3_637"
                     /transl_table=11
                     /translation="MTTQNLNKLPGTIAVPMDKIRITIYCPSF"
     CDS             13760..13984
                     /locus_tag="ctg3_638"
                     /transl_table=11
                     /translation="MRPIKNTTELIGIKDQNIIISLVFETDTHIEIQAKLDYPAPSCPH
                     CQEKMIKYDFQKNLKSLFSSKRERQLYYV"
     CDS             14093..14359
                     /locus_tag="ctg3_639"
                     /transl_table=11
                     /translation="MESLENTDNLLTFYQFPYQIWHSIYSTNLIESLNKEIKRQTKKKV
                     LFPNEEALERYLVTLFEDYNFKQNQRIHKGFGQCADTLESLFD"
     CDS             complement(14480..16660)
                     /gene_functions="other (smcogs) SMCOG1037:heavy metal
                     translocating P-type ATPase (Score: 523.1; E-value:
                     2e-158)"
                     /gene_kind="other"
                     /locus_tag="ctg3_640"
                     /transl_table=11
                     /translation="MSNKTHLSNYEEMMSEHHHNHEMVDMKHENHEMHNMHNMDNMHDM
                     DNMHNMHNMDNMHDMHDMDNMHDMDNMHDMDNMHDMMNHGGHMMHMGDMSKKLKVAIIL
                     MIPLLLISPIAGFTILKFPGSEILQLILGTIIFFYSGTPFFRGAKGELKSRKPAMMMLI
                     TMGISVAYAYSVYATIMSLYGHMGMNFWFELATLIVIMLIGHLIEMKAIMGAGDALKDL
                     ASLVPKKAHLKSGKDVELSELKVGDLLLVKENEKIPADGLILSEALVDESMITGESRAV
                     NKKPNDLVYGGSLNQNQPFEMKVTTLGKDSFLNQVAELVKKAQAQKSNLENMADRVAGY
                     LFYAALIVGIFSLIFWTISSNFSFALLLAVSVFVIACPHALGLAVPLVVSRLTSISAKN
                     GLLIQNRTSLEKINTIKYALMDKTGTLTDGKFIVRDVIDFTDETDILQIMAALEGSSTH
                     PIAQSIVSAAKPLKNLKVEAVENIPGVGIKGQVNQNFYQIVNYKYLRENQLSYDEQKIA
                     QYLDLGLTLSFLINEQQDVLGFIALGDSPKADAKAFINGLLAQGITPVMLTGDNKETAQ
                     KIASALNITEFRAELKPEDKAEIVKEYQKKAGVLFIGDGVNDSPALATATIGFAIGAGT
                     SVAISTADVVLVNSNPSDVLDMINISKRMLRKMKQNLWFGAGYNIIAIPVAAGILYPFT
                     GFYIDPLIAAVLMSISTVIVSINAMGLRYDKK"
     CDS             complement(16851..17117)
                     /locus_tag="ctg3_641"
                     /transl_table=11
                     /translation="MESLENTDNLLTFYQFPYQIWHSIYSTTLIESLNKEIKRQTKKKV
                     LFPNEEALERYLVTLFEDYNFKQNQRIHKGFGQCADTLEGLFD"
ORIGIN
        1 caaactgtgg atcatcggta ccaatacagc atccagcctc cttagctcag ttggtagagc
       61 agtggactct taatccatgg gtcacaggtt cgagccctgt agggggcatc aaacttcaac
      121 agtaaaagcc ttgataacca aggctttttt gcttgtctta agagcatttg ccccatcgtt
      181 tgccccacat ttttttatga gcaatctttc cagatatctc tgatttgatt aaattcctca
      241 aaaattttct cttctaaagt gtgtccatat acttctacca acattgaaat atctctatgc
      301 cctagaattt ttgcaataac tccaaggtca aaccctttgt gccagaggta gcttccatag
      361 gtgtgacgtg ctccttttgt cgtgataatt ggataaatgt ccaactcatt taagagaaca
      421 ctcaaagctt tattgacgct tgcaatatct ggaactgaat gaatatatcc aaaatgttga
      481 aagatcattc gatatcgatt tttgattcct aactccatgt ttgctctttc ttgctccgtt
      541 tgtaaaaggc gcaaaatttt gatacactct tcgtctattg gaaccatccg aatagacgtt
      601 ttattttttg gtggaacaaa cttatgagag agagtattat acctcctgta tgtttttaac
      661 aatcctctgt caaaatcaac ctcattccaa gttaacgcta ctaactctcc aaacctcatg
      721 cctgttttta atagaaaata gacgatataa ggaacaattg aacgttggta atcgaatttt
      781 ctctttactg ctaaaagtaa atccagatag tccttttctg tatgtaaata tttctcttct
      841 gtcatctgtt gttctttgga tgaaaacaac tcgacatgtt gtgtaaaatc atctattaga
      901 actttgtcag caattgccat ttggatgctc tgatgaatcc ccgtattcaa tctaccaaga
      961 aaatttctac caactgtttg cccatactta ttcataattc tttggtattc actcgcacga
     1021 atttgagtga cttttttatt tccaaataat ctttcaattg tgtttttacg gagaagatat
     1081 tttttctttg tttcttccga cctactactt ggtaaaattt ttagttcaag ccattcttga
     1141 tatagatcgg caagagaaat atctctagaa attctttttc ctaaacgaag ttcttgcaga
     1201 atcggttcag cttctgactc tgcaagtttt tttgttttaa aaccgctatt atgagcaaca
     1261 gtttttcctt cgttacgaat ttcataggtc cataaattac tatctcctcg ctttcggtaa
     1321 agaacacttg ccatattacg ccacctctgt tcctagaatc tcatttacaa cactttttgg
     1381 aacaaccatc aaacgtttgc gattataaaa tgtatagcct cgtgatacaa gtaattctct
     1441 tgcctgatgg atgatatcat ttgcagtgtg agggcgatag cccatttcaa ttaattcttt
     1501 gttgctaatt aaattattat ccatagttat cctccttatt gattttctaa agtcagaaac
     1561 tcacctacaa gtagttgtaa ttctgtattt aatttaggga gattctgtat taatacttct
     1621 tttaattctt ccgcaaattg attcgtttct tctctcaata gtttgcggac tcttgttttt
     1681 ttctttttga tgctgtctga ttttaaattt ggaaaagcta atgataacag ttcaggattg
     1741 cttagaaaga taattgtaaa ggctctttga tccactcgaa tatgttctag cttataaaat
     1801 ccgaaattat caagtcgatt cataatatct tgcaccatat cctccccaat cgctttagtt
     1861 ctgagttgga actctagtct ccaccaaaac ggatttacac ccaaatctag cttctcttcg
     1921 tgcttatgag caatgatttc tttattctta tcatataacc taacttgtac attactaccg
     1981 ctagaacccc aatatttcgt ctctaattcg ccccctctac catagaagac cttatgggta
     2041 acaccacctt taatatgttg caaattaacg atttcaggcc tgttgaaaat gtcaaatgcc
     2101 aaatcaaaac gagacaaacg taccgtcaat gaattcaatc tggcaaagta cattaattac
     2161 ctccatactt tcattccatc aaattctttt aaagtgttag gattgaaatc aatccgaatc
     2221 aattgttcac ctccataagt ggataattgg aaaaatataa tattgattga atcatactca
     2281 ttaaaatcct tagctaaagt aaagacatca tctcgcacgt tatcatgtat ttcaaatgag
     2341 tcaactcttg tacttattgc ctgtttcaga tttttgaaaa ttcgtcttag gggaccagtg
     2401 tctgtatccc agataaccgt taatctatca atactgacat ctaacctctg tactaattct
     2461 cctatttcac atcgttcttg aatgcttctt aaatcttgta tagaaatcaa caaaattgtc
     2521 cccccttctt ttagattttt taggcctcag aaacaccgtc aaatcaacgt ttgctcgttc
     2581 cgtcgttctt tggacgttgt cctaagtgta cctttttgct ggctgttaga atagccagct
     2641 tttgcttggc tagaaattgt ctggacggca gcctgcagga cttcgcctga cttcacgtca
     2701 ggctcgtccc ttgctcttgt ccacacaatt tctagctcca aggcttcgaa tagtcatcag
     2761 tcatagtcat agtctcatcc tcaaattcct cctcactcac tattcctaaa catatgagct
     2821 atttgtatca tttaaaaaat attttgagca gtcaactaaa aacttgattt gtaagtttat
     2881 aggtgataga ataagtttaa aatacaacat aggagtttat catgaccttt attattcaga
     2941 attttggacc caatttggca cgactacgca tagaaaaagg agtaagtcaa actcaacttg
     3001 cggaagattt aggaatcggt aaacaatcca tctctgacta ctaaaaacaa aaaagctatc
     3061 ctacctttgc aaatttggat aagatagcag aatattttaa tgcaactcca acccaactat
     3121 ttggaactag taaagagatt gaattagaaa agagtgttct tgaatcgaat gaatactctg
     3181 ataaagtaag tgagatctta aaggctgtca aatacatcga aaattttcta gaaactgatg
     3241 gacagtactt agaggattta ctttacctaa caagaggcaa acaactatac acagaagatg
     3301 gagacgagtt gtatactgat ccaacttctc agaaaagaac atttcataac caatatgaac
     3361 ctggttttat tgtagcaaga gacaaatctc cactagaact cttgattgaa aataaggaat
     3421 tatttgataa atagaaaaag cgagtttgaa ctcgcttttt ctgttatgaa agaaataact
     3481 tattttctag ttttttagat aaatcctctc tccaaatatc cgtcacggtc gcttcttccc
     3541 agttctttgg gcttacgcaa gattttaatc aattttgagt taaaaataaa tactctaaat
     3601 actcattcaa ttcattaatt atttagtcaa tggttgcttt gtatccacaa ttccaaatag
     3661 ttctaaatga gattttagga actttgaaaa ctttaaaaaa cgcattctta tcactttgaa
     3721 gataagaaaa gagagaacga attgtgtcct ctctcgatgt tagcttttca tcaactcaag
     3781 acagttgaca aagagccttt cagatataca atttgtctat agacactatt ggcataacta
     3841 ctttttcaaa tgaatcactt tatcatagcg cttcaagtct tccttggtgt agtggtgaat
     3901 gacctccacc acagcttgag gaagtgaaaa gagcagctgg ttgatttttt cttgattttt
     3961 ggcgtccagg ttagccttga cctcatctgc taggataaac tgtcgcttgt gatagagagc
     4021 acgggcgatt tcaaggcgct gtttttcacc gcctgataaa gtttggttgc tgggtacctt
     4081 gccttttagg ctgaggagcc ctgtttcttg caagatgtta tccattcttt gctggtcaat
     4141 ttcctgtccc agagcgatgt tttcctccac agataaatcg tcaaaaacat gactagattg
     4201 caagatatag gcaccagcct gatagagttg acagctggtt agttcccgtc cttgataacg
     4261 aatttgcccc tgactaggat ggatttcccc gtataggatg ttgagcaggg tggttttgcc
     4321 cgctccgctt tctccgatga tagcaatctt ttccccagcg tggatagtca gatcacaagg
     4381 agctagaatg gtctccccat ccttctccac actgacctgc tccaactgga taggaaagac
     4441 agattggtca aatatgctgt cagtagccaa cttatttcca aacaagtctt gatacttatc
     4501 gcagagggac ttggcagact tgcgggtatt gataaagtag gacagttctt gaaactggta
     4561 gccgatgttg tgggagacca gataaatgcc gacaaaacta gccgcagaaa ggtagttctg
     4621 gtaggtcatg aatccgccaa tcacaatggg cgccacagag caaaatgcat ctatactgtt
     4681 gataaataaa ctgttcagtg accgttgctt ttcgtaggac acttcttctt gcaacgcctg
     4741 ttctaggtct ttagaaaatc tcttgaaaaa caaattctgg ccctgataat gacgaatagg
     4801 agcaacacct gcaatcatat tgttgacacg ggcgatataa ttctgatttg ccagggattt
     4861 ttgctccgca atcctatcca aacgcttcga acccagtccg ctacacaaaa ctggtacaga
     4921 gtaaaagatg ataaacaata accccagata gaaattggtc cagagggcat atgcgatgga
     4981 aacgactgta aaacctagcg aggatacgat aatgacggtc ggctctatat agctattttc
     5041 caactgttgg acatcatttt ccagatcaga cagcacctcc tcatcaggaa tctgacggct
     5101 gtataaaaaa gtccgaaaaa tagcgcgttt tatcccaacc ttaaagtcag tcatcaaacg
     5161 agcatagtaa tagcgcttcc cagccaagcc caggacaagc accagattgc ccccaatccc
     5221 ccagagcaaa atctgccaga ggagatgcaa ctggcggttg gtaaaactag cgacgatata
     5281 ctggataagg gcaggggtga taatggcctc taaccaagtg atgacgatgg ctagaaaata
     5341 gaaggtgaga tgttttttcg ttacataact cctaagcata gcgtataaac ccccctaaaa
     5401 ttatttacca acctagataa tttttctctg tccttggata aatatataat ctgtttaata
     5461 cagtattcca tcagttctgg tttagagcat tcaagaaatt ccccatcttc actaattaca
     5521 gaagaatatc catcaataac attggcaacg cattccaagc acatacctct acaccagcag
     5581 tttttacact tttcaaagtt atctttgttg ttaaatgatt ccgctttagg actgttgtga
     5641 gttccccaaa atctgaaaca tagtttctta ctaccatcta catcataagt taatgtattc
     5701 gaagggtcaa tatcatcaca aaatgtacga ttcgtactct tgtatatcat tgatattaat
     5761 acatcatata aaataggact gataaatgcc ttctcattgt tgttgattac atgttgaatg
     5821 gatttatcta tgaactgttt tctttcagcc aaactttttt ccatctcttt cacaattagc
     5881 actttatttt tagtaaaaac atcatttata ttaaaatgca catccatatc agtaaaatat
     5941 tgaaagatat cttctctact tagaccattt ttttgatgaa gtctagtata tgtcgaggct
     6001 atttcaaaat tttcataatc aatattcttt aaataattaa taaaacgtaa tgtttttcga
     6061 tggctccctc ttcctctgag tctatcatga acaatttctg gtccatctaa acttatggtt
     6121 aaataaggat gaaatttaac aagcatttct ttaacacgct tatttaaaac agtaccatta
     6181 gtaactgttt caattttcac tacatttaat aatgtagata atttttctat aaaatatata
     6241 aataattcta tatttaaaaa aaggttctcc cccgaaaagt atgagacggt tgatttgtgt
     6301 aactccttta cttgctatct cttggataat attatcagca gtagttaaat ccataatacg
     6361 attatccata ccatagttac caccatctgc ataacaatac gaacaagata aattacaact
     6421 attagaaata tttataacta ctttttttaa tacaccatct tcaacagaat ctagagttgg
     6481 tgaactttgt tttgaaatag gtgacaaaga taaagtaaaa ttaacagaat caaaataata
     6541 tgttcctata tctgtttcta ttgtctttat cataattatc ctccagacta aaaactgaga
     6601 tgaggaatca ctcctcatct cggaagaagc tatcgaccac cgccacaaga atgacttgga
     6661 ccacagctag cattaattac atacccttga tcaaactcta aaagttcttc aaggtcaatc
     6721 acctgaagtt tttccatggt ttttacctcc tttatttgat agtttcatta tataacctta
     6781 tcagaagagg ataatatttt cccttatacg caattcacct catgtcatct aatacttttt
     6841 gtaaataatt ttcaaatttt atagatattt gattgctatc taccaatttc gtggcagcaa
     6901 tacattttct catttccaaa acagcatgtc gattattatt tttctttaga tcatataaat
     6961 tattagcata atggagcact agtttttcat acatttcagt ctctgaaaag ttacaatatt
     7021 ttagctgttt ttcaaaataa agagcgtcca tccattcatt gcgttcaata caggtgatat
     7081 aagcattgag caacatagtt gccaataaac gtctattatt tggaatatct ctataaaaat
     7141 ccaaacgatg acacatttct ttggctaaaa tcatcattgt gttatgattt aaagcgtcta
     7201 ttgtattcat aaacagtagc aattcataat aaccccagta ttccgcagaa aacaagtaat
     7261 cactgatagt aacaatctct tggtctgtta cataagtttc tcctgataaa tcctgtaatc
     7321 ttattttaat caaaattgtg ttaaatgaag cgaaaggttc ctttttatcc ttcttttcca
     7381 tttggctaat taatagcttt ttcattccgt ctatatcacg atttgatact aaataccgaa
     7441 tcttttctaa aagttcatta aagtcatctc tgcggaaatc acgtacagcg taaacaaatt
     7501 cttcgatagg catatgtatt gcatctaacg ctaaaaaaat tgctgatggt taaatcagcc
     7561 tcatcatttt caaatcttga gagatgggaa cttgaaagac ctgattttgc aacatttttt
     7621 aaagataaac ctcgagattc tctaaatttt ttaaaaattt ttccatattt cattctagtc
     7681 acctcctaaa ttgcttataa gggaaatttc ttcacaaata ttaaaaatat tatatcatat
     7741 aagaaaacga aaagaggtat ttaccatgaa taaaaaagca ttgtttagtt tgttgtttgt
     7801 aatacttgaa ggtattatcg ttatcggagt aggttagcca aatgataaag agattaggca
     7861 agaaacctta aaaataaaaa atagcttaga attgcgtcat tataaacgtt gattccaagc
     7921 tatttttggt tattaaaatt ttaatcagaa gggtaaactt gtagtttttg cccaacctct
     7981 cttgatttta tggaaaaaga atcccgtatt ttggatacga aatgctttca ataagtgtaa
     8041 atcagtttta acgtttacta aatttcgatg ctttacgagc ctttttcaag cctggttttc
     8101 aaagcaagtt ggaaaccttt atgagtcatt cgtttttgcc ccacttttgc cccattttga
     8161 aataattata tttaaaaatg ctccaagtat cttctaaaaa taacttatat ttcaacattt
     8221 ttgattattt tcaatatgaa aaattcatac aaattcatgt agggggcata taactataca
     8281 taaaaaagcc tttgtttaaa ggcttttttg cttgtcttaa gaggatttgt cccatcattt
     8341 gtccccgaaa taatttccaa acttttgata aatattattt ttgtataaat taatttttgt
     8401 tgtgtatagt aacattgaat tctcaattta aagtgtaata atactatgaa atctatctag
     8461 tagtttttcc tgtaagtgat gagagacagt aatgtacatc cttgtaggat cgtttaatag
     8521 ctggttctca attagaaaag cgttatctct atctaaattt gccatagatt catccattat
     8581 tattacgtta gttttagtaa gataggcacg tgcaatacct aatctttgct tttgcccttc
     8641 tgataaaaaa gacatactta cttcatcatc taatcgtgga attaaatcta ttaaattaac
     8701 ttgtttaagg atattgataa tttctgattc atttatttta ttatcccaaa gtgttaaatt
     8761 atttctaaga gaatcatgat aaatatgagt aatatttcct atatatgaaa cgcttttaaa
     8821 caattgagat tcttcaatat cagatatctc tacatcattg tattttacac ttccactata
     8881 ttgcttatta tttcctaaaa ttatatttat taaagttgat tttccactac ctgactctcc
     8941 aactatggca taattttttc ctttttcaaa actacaattt atatttttga aaacttcctt
     9001 atctttgaag gaatacccga cattagttaa cttgatttct tcaatatctt tatcaatata
     9061 tctataatgg gaactcttct caaaagctcc aaatttttca aatatactat ttactgatga
     9121 tattgatacc tgtaattgat taaacgtagt taatgagtta aatatatttc cggaaatttg
     9181 tccgactgat gatattgaac caattgaaac ttgttttaaa atgataagat aacctgttaa
     9241 aagtagtact aacatttgag aaataattga aaataaactc attattattt caattaagct
     9301 actagtttta ataaatacta ttttttcaaa aataaatttt tttattacct ctccacattt
     9361 aattgataac atctcttttt tatttgaata atatagcgta tcatatccca gtaattgatc
     9421 tgttagtgat gaaataaatg tttcattacc tatagaaaat cttttcatag ctttttccat
     9481 cttatgggca aaacttcgtg gaaggtaagt taggatcaaa gtaagtagta tagataaaag
     9541 cactattcta taatcataac taaacagagc aataattgaa aaaaaagttg tgaaaactgt
     9601 tgaaactaat gaataaaaac tttcaaatcc gctttcttcg ataattttta tatcgttatt
     9661 taaaattgac aagtgttctc caacagtctt atttttaaat tcactaaacg attttctagt
     9721 tagactgtta atataatcat ctctgagaga aagagtcatt ttttgaatta atttagtctg
     9781 atttactcta attaagtatg tatctgccaa aaataacaaa taaactccaa attcaatgcc
     9841 taaccatatg aggaagcctt taaaatcact ttcaaccaat ttatttaaca tgattgagag
     9901 tgtgactgat gctccaacta aaaatgcaga actaaatcct attaatatta tatgtataag
     9961 atttagcagt ttatatttta gtatatattt tttcattatg ttattcctta attatattta
    10021 gcaactcatt aataaagtac aactgcccca acattccttt tgaatatgta taatcaattt
    10081 cttcggacat cgggtctatc aatatagttt ttgtattttg tttaatagaa aaatcaaaaa
    10141 tatgttcgca aatcttaata ctcgttttaa gaaatgaagt ttctttaaaa taataataaa
    10201 gccaagcatt tgccaaaccc aatcctgcta atccataata caatgaggtt cccttagcat
    10261 atgtataact aattccttct gataaacttc taatccattc atcgaacttc attgtattgt
    10321 tatttttact gaacttaata agttcaatga ttaacccaga gttaccagtt attaaatatg
    10381 ggctaaaata ctcattggat tttatatatt tcactccatc aatacactta atatcatttt
    10441 tgatgattga atttaggacc tttataaagt agactctatc acatatttta gtgtcattga
    10501 aaagtctgag tagataatat ttttgatagt agctcatatt atgtagtagt tcatctaaat
    10561 tacaatttaa aaaaagttca aaattattat caagtatagc gattccgatt aagtcatcta
    10621 tacttttatt acaattatca taaagagaag agaaactggg atcgctagaa aattttaaat
    10681 ccatattact aatatgttta taattatcaa ttgactctaa tattgttttt ccataaattt
    10741 caaaagtatt atgggaaagt atagtttctg ttaaatcttg ttgcattcta actatttttt
    10801 ctatatttaa acccatttca ataaatttta ttataaatgt attcttaaag tccactatac
    10861 taaaatcatt aataaatttt tttcttaaag atttaggtaa attattctct aaactcattt
    10921 tataaaataa atttaaggta ctcactcctg tattatcata ttttaaaaga ctagtagaat
    10981 tagttaataa atcaattata caataccaca ttttaacaat atctcgctgt tcattttttt
    11041 gagaaatgtt tttgggatag cattcatttg tcgtctcaac aataattcca tcattcttat
    11101 tatatgcggt ttcgagatca ataaaaaata ctctatcatc atttgttaaa agaatattac
    11161 ttgaagatat atcctctaat attattccct cctgatggat tttatataaa cttaaaaata
    11221 gattagaaat tatttttttt acttttttat tatatcttcc taactcgcta gaatttcgtt
    11281 ttatcaacaa attatattca ggctttaaaa tatccaatct ttgtccatca atgaattcct
    11341 caacaagata taaatttccc tcaattgtaa agcactcaat gtaatttgga atatcgactt
    11401 tacctttcaa tttttttaga atacattttt catttaaaag gagatctatt gctaaaatct
    11461 tttctgtaat atatactttt tttctagctt cttttataat aaccttttct tcattaatag
    11521 tatcaatcgc aatatataca ttacctgctc ctgatttatg aataatagat tccatttgat
    11581 atctatcatg gaataaagat tcaatattat agtcatctac aactttatta aatatgatat
    11641 cttcaacaaa tgggggacat gtatagtatg gttccgttat atcttcataa aaggttccat
    11701 taaatttaag ttttggtcgc tcattattaa ttaaacgtgc attcattact ccatatctat
    11761 aaaaaattat ttctgagtct ttataacttc tatctgtcaa aatttgaact ccagtatatt
    11821 tgggtatctt atcatatagt tcttccaata ataataaaaa agtttctttg tttttaggat
    11881 atatagttat aaattttcca atctctaatt gcgaaacgtg ttttgataaa atacggaata
    11941 actcagatat tttattgata tacttaaatg gcgtttgaaa aatagaacaa acatggtaaa
    12001 cattatctaa aatagactga taatctatta aattagcaga tatatgaatt ttccaacctt
    12061 gataaggaac aaaagcattt gaatatgaaa tataatcata tatttcccct ttttttctat
    12121 taatgattct cttttcactt ggtgtaatta gttcttccat gataaatctc ctattaaaaa
    12181 taaaatactg ctgtataact atataactag tgtaacagca gtattttatt tttagtaaaa
    12241 agtgtcatat aatagaattc aataattctt catattcatt ttctctcatt agcagtaaat
    12301 tctcagcacc taaatttttg agggattcca aagctagttc aattttcttc ttgccgactt
    12361 ctattttacc tataagtatc caatatgtac ctattaatat attatattcc actcgctcat
    12421 agagataaac ttcaggaatg gtaagtgtat caaaaagatc aatatagaac ttggcataat
    12481 ttagttcttt cctctctaaa aatattgaga ttccgtttaa aataagatca atttttattt
    12541 ttttattttc ctcattatta ccaaataaag tagtcttata aataatttct tttattaata
    12601 aatttaatgt atttgtaggc accgctgaca tactattacc taatattact aactctcttt
    12661 tcccccattg atctacatcg aaaagataat cagaaataac ttcaatatgt tttttattca
    12721 tttttttacc tgttatcgat attaaaaatg aatcaatcaa aatagaatta tataaaaata
    12781 tttttttgtg tgttgaatta aacttttcta tttcttcata ataatatttt tttagagcag
    12841 gtatgttatt ttgttgaaat gccttactga cccttgctag taattcctca gttcttgtag
    12901 gattatcttt cgataaaatt ccgtaaattt cttcgatact tacatccaaa ttttccaata
    12961 tacaaagaaa acgagaaagt gaaatctcag actcgccacg ttcaaactta gataaaaacg
    13021 aaaccgaaag ataatcacca gcaacatctt ttaatgaaag tttttttgat aatctaattt
    13081 ttttcgttaa agaacctatg tcaatagtat caatcataaa ataactcctt ttatacaatt
    13141 ataacaaaaa acgcaaacat agtgcagtct gcgttaacct tttgaatatt aggagtatat
    13201 tgtaatacga agtctatctt taaattcaaa agaatcactt ggtaaactgt tcaaaatttg
    13261 aataatcatt tttctcctta aaaacttgga cagtaaatcg taatacgaat tttatccatt
    13321 ggaactgcaa ttgttcctgg taacttattt aggttttgag tagtcatttt tttctccttt
    13381 ctaaatctta tagacatatt atatattttt gcaataatta agtattaata ttttcatata
    13441 taggaattgc ccgatactgt caataattat gtgtaaacac tcaagtagag ttgaagaatg
    13501 ttaatcaaat aagctttcaa gtgtgtcagc atattggcca aaccctttat ggatgcgttg
    13561 attttgcttg aaattataat cttcaaacag ggtaactaaa taacgttcca gagcctcctc
    13621 gttaggaaaa nnnnnnnnnn ctctataatt tctgtagtga gtaaaaccac tgtagagatt
    13681 atagagcttt ttgaacgcag acaaaaagtc ccataagaac tataatgaaa agcgacgaaa
    13741 ctaccattag gaagaactta tgagacctat taagaatacc acagaattaa taggaattaa
    13801 agaccaaaat atcattattt cacttgtttt tgaaactgac actcatatcg agattcaagc
    13861 aaaacttgat taccctgcac catcatgtcc tcattgccaa gaaaagatga tcaaatatga
    13921 ctttcaaaaa aatctaaaat ccctcttctc gagcaagcgg gaacgccaac tctactacgt
    13981 ctgaaaaaac gtcgtttcca gtgtaaaagt tgtagaagtg tcacggtagc nnnnnnnnnn
    14041 acaagcttta gagaacttta tctccgaatg gaaaccaaag tataggaaag tcatggaaag
    14101 tttggagaat acggataatc ttttaacttt ttatcagttt ccctaccaga tttggcatag
    14161 catttattcg acaaacctca ttgagtctct taacaaagaa atcaaacgtc aaacgaaaaa
    14221 gaaggttctt tttcctaacg aggaggctct ggaacgttat ttagttaccc tgtttgaaga
    14281 ttataatttc aagcaaaatc aacgcatcca taaagggttt ggccaatgtg ctgacacact
    14341 tgaaagctta tttgattaac attcttcaac tctacttgag tgtttacaca taattattga
    14401 cagtatctaa tctttaagta tatttaagtg ataagagttt cataattagt atgaaaaaaa
    14461 tagaagagca taggctcttc tattttttat catacctcaa tcccatcgcg ttgattgaga
    14521 caatcacggt tgagattgac atcaggactg ctgcaatgag agggtcaata taaaatcctg
    14581 taaatggata aagaataccc gctgcaacag gaatagcaat aatgttatag cctgctccaa
    14641 accagaggtt ttgtttcatt tttctaagca tgcgtttgga gatattaatc atatccaaga
    14701 cgtcacttgg attggagtta actaggacga catcagcggt actgatagca accgaagttc
    14761 ctgctccaat cgcaaaacca atcgtagcag ttgcaagagc tggggaatca ttgacaccat
    14821 caccaatgaa aagaacgccg gctttctttt ggtattcttt cacaatttct gctttatctt
    14881 caggttttaa ttccgctcta aattcggtaa tatttagtgc actagcaatt ttttgagcag
    14941 tttctttatt atcacccgtg agcataacag gggtaattcc ttgggctaat aaaccattaa
    15001 taaaggcttt cgcgtctgct ttaggagaat ctcctaaggc aataaatcct aaaacatctt
    15061 gttgttcatt gattaggaaa gataaagtta aacctaaatc taaatattga gcaatctttt
    15121 gttcatcata agaaagttga ttttcacgaa gatatttata gttaacaatt tgataaaagt
    15181 tttgattaac ttgcccttta attccaactc ctggaatatt ttcaaccgct tcaactttta
    15241 gatttttaag aggtttagca gctgaaacga ttgattgagc aatcgggtga gtggaacttc
    15301 cttcaagtgc tgccatgatt tggagaatgt ctgtttcatc agtaaaatca ataacatcac
    15361 ggacaataaa cttaccgtca gttaatgttc ctgttttatc cattaaggca tatttaattg
    15421 tatttatttt ttccaaagag gttctgtttt gaattaataa accattttta gcagaaatac
    15481 tggttaagcg agaaacaaca agtggaaccg caagacctaa agcgtgtgga catgcaatta
    15541 caaaaacaga aaccgcaaga agtagagcaa aactaaagtt agaactaatt gtccaaaaaa
    15601 ttaatgagaa gataccgaca ataagtgcag catagaaaag gtaaccagcc actctgtcag
    15661 ccatattttc caaattagat ttttgagctt gggctttctt gactaattca gccacttgat
    15721 tgagaaatga atcttttcca agggttgtga ctttcatctc aaatggttgg ttttgattga
    15781 gggaaccacc ataaacaagg tcatttggtt ttttattgac tgctcggctt tcaccagtaa
    15841 tcattgactc atcaacgagc gcttcactta atataaggcc atctgcagga attttttcat
    15901 tttctttcac taaaagcaaa tcgccaactt ttagttctga aagctccaca tccttcccac
    15961 tttttaagtg agcttttttg ggaacaaggc ttgctaaatc tttcaatgca tcgccagcac
    16021 ccatgattgc tttcatctca atcaggtgac caatcaacat aatgacaatt aaagttgcca
    16081 gttcaaacca gaagttcatg cccatatgtc cgtaaagact cataattgtg gcataaacag
    16141 aataagcata ggcaacggaa attcccattg taatcagcat catcatggct ggcttacggc
    16201 tttttaattc accttttgct cctctaaaaa aaggagtccc agagtaaaag aagataattg
    16261 taccaaggat aagttgcaaa atttcacttc cggggaattt aaggatagta aagccagcga
    16321 ttggtgaaat gagtagaagc ggaatcatta gaatgatagc cactttgagc tttttactca
    16381 tatcacccat atgcatcatg tgtcctccat gattcatcat atcatgcata ttgtccatat
    16441 catgcatatt atccatatca tgcatattat ccatatcatg catatcatgc atattatcca
    16501 tattgtgcat gttgtgcata ttgtccatat catgcatatt atccatattg tgcatgttgt
    16561 gcatctcatg attttcgtgc ttcatatcca ccatttcatg attgtgatga tgctcagaca
    16621 tcatttcttc gtaattagac aaatgagttt tatttgacat attttcctcc taaatgaatg
    16681 ctttgaaatt tctatgtgta tatagtttac atctgtaaac tataaaagtc aaaaattttg
    16741 tattctataa atgttacgaa ataataatcg atatgtttct tttgtaactt aaatgtgatg
    16801 tcgatactgt caataattat gtgtaaatac tcaagtagag ttgaagaatg ttaatcaaat
    16861 aagccttcaa gtgtgtcagc acattggcca aaccctttat ggatgcgttg attttgcttg
    16921 aaattataat cttcaaacag ggtaactaaa taacgttcca gagcctcctc gttaggaaaa
    16981 agaaccttct ttttcgtttg acgtttgatt tctttgttaa gagactcaat gagggttgtc
    17041 gaataaatac tatgccaaat ctggtaggga aactgataaa aagttaaaag attatccgta
    17101 ttctccagac tttccatgac tttcctatac tttggtttcc attcggc
//
