LOCUS       gnlProkkaHNGJNMJB_64    6787 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HNGJNMJB_64.
ACCESSION   gnlProkkaHNGJNMJB_64
VERSION     gnlProkkaHNGJNMJB_64
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:08:40
            Original ID  :: gnl|Prokka|HNGJNMJB_64
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6787
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6787
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[3552:6444]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3553..6444
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..6787
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6787
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             complement(676..1884)
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 278.7; E-value: 1.3e-84)"
                     /gene_kind="transport"
                     /locus_tag="ctg45_1"
                     /transl_table=11
                     /translation="MNKKEQQNTYLLVGSRIISRVGDIMFDFANNTFLSSVNVKSLMLV
                     GIYQTLENIISVIFNLFGGVLSDNFQRKRIIILTDILSGVLCLALSFISNQQWLIYAVV
                     ITNIILAFFSSFSGPAYKAFTKEVVEADNISKLNSLLESFITVVKVVVPLVSVSLYGLL
                     GLYGILRLDGITFIASGLLILFIRPILEESTGKQVFSLSKIFSDLFEGGRYLASQKEIL
                     YLVILSAIVNFFLAAYNLLLPYSNQMFPRVTVGLYGVFLGAEAVGGLIGASLSSILNKV
                     LKIKTMILYLGVSGVFLSLTPMVYCVFPSAYMLALYPALFNLFLTMFNLQFFSYIQKNV
                     DNVFLGRVFGIIFTVAILFMPIGTMTFTFLLSPKNIFNFVIVGLSIGGISLLFYRIFSK
                     RLR"
     CDS             complement(1910..3556)
                     /locus_tag="ctg45_2"
                     /transl_table=11
                     /translation="MSIYKDIVEGYQLNNIQEKDKLNNVLVQLNEKDDQEMINRKNFIG
                     HFTASAFVISKDNRRLLMVHHNILKRYLQPGGHIDKNDRNPLDAAKRELFEETGIDSEI
                     LTYQCAEPLNSLIPFNVSVHKIPENKLKNERSHYHYDLQYLFYIENEVDVKIDSNESSS
                     YEWIQLDNVKDMDGYKEIIKKIEKLEAASQERFLSNMLKGASFEDISCITVQHIIPSTI
                     PIIMTLQKIFGHRLLVCAKPNSVDKMVWHKLENMGVRLTLASRDEYFNVDYLGIKSKTI
                     LLDIGGYFASIAQIPNLPIECIIEDTENGIQKYENVIDQIEYPLFSVARNPLKKNEDYL
                     VGADIVFGTDYILHQKNLLMQYMQVVCIGYGKIGYGICTKLRELGIRPKVLEKDSMRTI
                     QAVRDGCDILLEKDFKNIDLIFCATGSKSLDILDFRSIKDGTFLVSATSSDDEFNYSYL
                     LDEYEEIVETSLITRYESEDNYFYLLNQGTPTNFVVNSALGNYILLVQAAILYTAKKFI
                     EDREMAIAKQVNTLSDEDNYNIAKQWLEEFC"
     CDS             complement(3553..6444)
                     /NRPS_PKS="Domain: AMP-binding (6-388). E-value: 7.5e-65.
                     Score: 210.9. Matches aSDomain:
                     nrpspksdomains_ctg45_3_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     172.5; E-value: 2e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg45_3"
                     /sec_met_domain="AMP-binding (E-value: 9.9e-65, bitscore:
                     206.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-07, bitscore:
                     20.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILKTFSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLL
                     NSDEETVPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDR
                     DVKLENHSVTLLLLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNID
                     WLVKEFYKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGET
                     IEKKKITHLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRV
                     FNLYGPSETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVT
                     EGYRLQPELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQVNGIRIELDEVK
                     SIVDKLKSVKSSRVVFYKKKLVVFYEADLNIKEDIIRSLPSYLNPTVVKVESYYLNQNR
                     KLDVPKMLEIYYYKKQSQQGDDVRKNILDVLSKFERVDITDLDSLELVRFYLEIEDIFD
                     IEIKENDFYRLKSVDSIVDYIRNKSFFQERSTEPNDSFTKEHDLVNLEYNLTKMNYRYL
                     KNIITPSPTQKRLYKNNQNRVIGFNLALEEVTYLELNKLHHIIKYLSYKIDIFRLVVEK
                     EQTRFSIGIVNEGDYSPNIIVLNNLPTELELQGILDNIEVIPIPIIVVGTRDKKVRFYF
                     PYHSIDASSLNKLGDTVYQLYEKKIVIDEVPSSSLVAFSQFKREVLQNDVSGDVLARLP
                     KIKPAIEFEKLNDEVQCFQVSLPEDIKGDDVYLFTIYAISQCILSDYNLSAISGGLSLD
                     FRDYEQFDAYDLIGDIHKKIPFQVNRTETFEEFKNSHFKILEIYRTGIDYYEIAMLGND
                     MSAKEVQERLNNLSLSINFIGEAFRLKDTINNIIDVDFDKNFINVFVHERFAYAVIKSE
                     LLSNSVYDLMHKDSKFELKVIDKKRLENEETNR"
     CDS_motif       complement(4624..4671)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg45_3_0004"
                     /evalue="1.30E+01"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg45_3"
                     /protein_end="607"
                     /protein_start="591"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="NNQNRVIGFNLALEEV"
     CDS_motif       complement(5251..5307)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg45_3_0003"
                     /evalue="2.60E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg45_3"
                     /protein_end="398"
                     /protein_start="379"
                     /score="20.0"
                     /tool="antismash"
                     /translation="SRIDSQVQVNGIRIELDEV"
     aSDomain        complement(5281..6426)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg45_3_AMP-binding.1"
                     /evalue="7.50E-65"
                     /label="ctg45_3_AMP-binding.1"
                     /locus_tag="ctg45_3"
                     /protein_end="388"
                     /protein_start="6"
                     /score="210.9"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="FSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLLNSDEET
                     VPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDRDVKLEN
                     HSVTLLLLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNIDWLVKEF
                     YKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGETIEKKKI
                     THLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRVFNLYGP
                     SETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVTEGYRLQ
                     PELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQV"
     CDS_motif       complement(5383..5454)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg45_3_0002"
                     /evalue="2.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg45_3"
                     /protein_end="354"
                     /protein_start="330"
                     /score="19.7"
                     /tool="antismash"
                     /translation="ELLIGGNGVTEGYRLQPELNKAKF"
     CDS_motif       complement(5971..6027)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg45_3_0001"
                     /evalue="1.00E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg45_3"
                     /protein_end="158"
                     /protein_start="139"
                     /score="15.1"
                     /tool="antismash"
                     /translation="AHIICTSGTTGVPKKVFLT"
     CDS             complement(6634..6786)
                     /locus_tag="ctg45_4"
                     /transl_table=11
                     /translation="MDNQKDLQKFVNKRLEELQKDGTLAKLAEKFFGNKDYIPTKDALK
                     VPSKK"
ORIGIN
        1 tgtaacagaa ttcactaagc ttaactaata cttaaacata atcaaagtga taagaaaata
       61 ctatcaccta aaaatatcaa ttgtttgaca aagagccgaa ttgcttcgtc tttctgaacg
      121 cagacgggtt gtcttaaacg acatggtagc tctagctcag cctttaccag agtatgacat
      181 cttacggtca attcctggca tcgcagaaac cacagcgaca tctatcattg gcgaattggg
      241 agatattcgt cgcagtatac caatcaaatc aacgctttta ttggcattga cctgagacac
      301 tatgaatctg ggaactttct cgctaaggaa cacatcacta aacgagggaa tccctatgcc
      361 agtaaaatct tgttcaagta cattcacaac atcgcttcag ctagtcatac caatccctgc
      421 aatatcgctg acttttatga gaaacgaaca agacatttag agctatttct aaactaatcg
      481 gcgacccatc tactgtctct aaaaaagtat gtaaacacct taccatcaag gaatcaatca
      541 acactcaaaa tgtgaggccc gcccacttct aaaacgatta ccttatgtgt gtaatggttg
      601 ccctaacaag tatataaatt gtgactttac taagcaattt tactacgcca tcggagctaa
      661 aattactctg aaaatttacc tcaatctttt gctaaaaatc ctataaaaga gaagcgaaat
      721 acctcctata gataaaccaa cgataacaaa attaaagata tttttagggc ttaaaagaaa
      781 agtaaatgtc attgtcccaa tgggcataaa taaaattgca acagtaaaaa taatcccaaa
      841 aactctacca agaaagacat tatccacatt cttttggata tatgaaaaaa actgtaagtt
      901 gaacatagtc aaaaacaagt tgaataaagc aggatataac gcaagcatat aagcacttgg
      961 aaaaacacag tataccatag gtgtcaaaga tagaaaaaca cctgatactc caagatataa
     1021 aatcattgtt tttattttca aaactttatt gagaatactg cttaaagacg ctccaataag
     1081 accacctact gcttctgctc ctaggaaaac accgtataag ccaacggtaa ctcttgggaa
     1141 catctgattg ctatatggta acaacagatt ataagctgct aaaaagaaat taacaatcgc
     1201 agataaaata accaagtaca aaatttcctt ttgactagct agataccttc ctccttcaaa
     1261 aagatctgaa aagattttcg ataatgaaaa cacctgtttc ccagtacttt cttcaagtat
     1321 gggacgaata aagagaataa gcaacccaga tgcaataaat gttatcccat ctagacgtaa
     1381 aataccatat aatcctagta aaccgtatag agataccgat accaggggaa caacgacttt
     1441 aactaccgtt ataaacgatt ctagtaatga gtttagtttt gaaatattat ctgcttccac
     1501 cacttcttta gtaaaagcct tataagcagg gcctgaaaat gatgagaaaa aagctaatat
     1561 aatgtttgtg ataaccacag cataaatcaa ccactgctga ttagaaataa aagataaggc
     1621 aagacacaat actccgctta aaatatctgt taaaatgata atccgttttc tttgaaagtt
     1681 atcagacaga acaccaccaa aaagattaaa aatcacactg atgatgtttt ctaatgtctg
     1741 ataaatacca actaacataa gtgacttaac atttacactc gataaaaaag tgttattcgc
     1801 aaagtcaaac ataatatctc caacacgaga aataatacgg ctccctacaa gtaaatatgt
     1861 attttgttgt tcttttttat tcaaaataaa ctcctcagat atttgttcat tagcagaact
     1921 cttctaacca ttgcttcgca atattatagt tatcctcatc cgaaagagtg tttacttgct
     1981 tagctatagc catttctcta tcttcaataa acttcttagc tgtatataga atggctgcct
     2041 ggactaataa aatataattt cccaaagcgg agtttactac aaaattagtt ggtgttcctt
     2101 gatttaacag atagaaatag ttgtcttcac tttcatatct agtgattaat gaagtttcga
     2161 ctatttcttc atattcatcc aataaatagc tataattaaa ttcatcatca ctagatgttg
     2221 cagagactag gaaggttcca tctttgatag agcgaaaatc taaaatatct agactttttg
     2281 aaccggtcgc acaaaaaatc aaatcaatat tcttgaaatc tttttctagc aaaatgtcgc
     2341 aaccatcacg taccgcttga atagttctca tgctatcttt ttccagcacc ttcggtctaa
     2401 taccaagttc tcttaatttg gtacagatgc cgtaaccgat tttcccatat ccaatacaaa
     2461 ccacttgcat atattgcatt aataaatttt tttgatgtaa tatataatct gtcccaaaaa
     2521 caatatccgc accaactaag taatcctcat tcttcttcag gggatttcta gcgacagaaa
     2581 ataacggata ttctatttga tcaataacat tctcatattt ttgaatccca ttttctgtat
     2641 cttcaatgat acactcgata ggtaagtttg gaatctgagc aattgaggca aaatacccac
     2701 caatgtctaa taaaattgtt ttactcttta tccccagata atctacatta aaatattcat
     2761 cccttgaagc taatgttaat cttaccccca tattttctag cttgtgccat accatcttat
     2821 caacagagtt tggtttagca cacactaaca aacgatgccc aaatattttt tgcaatgtca
     2881 tgataatcgg tattgtactt ggaataatat gttgtacagt aatacatgat atgtcttcaa
     2941 acgatgcacc tttcagcata ttagataaaa aacgttcttg agaagctgct tcaagttttt
     3001 caatcttctt aatgatttcc ttatagccgt ccatgtcctt tacattatct agctgaatcc
     3061 actcatagga actcgattcg ttgctgtcaa ttttcacatc aacctcattt tcaatataaa
     3121 ataaatattg caagtcataa tggtagtggg aacgctcatt cttcaattta ttttctggta
     3181 tcttatgcac agaaacatta aaaggtatca agctattcaa tggttctgca cattgatacg
     3241 tcaatatttc agaatctatc ccagtctcct caaacagctc acgtttcgct gcatctagcg
     3301 ggtttctatc atttttatca atatgccccc caggctgtag gtatcttttt aaaatattat
     3361 ggtgaaccat caataaacgc ctgttatctt ttgaaataac aaatgctgat gctgtaaaat
     3421 gcccaatgaa attctttcta tttatcatct cttgatcatc tttttcatta agctgtacca
     3481 aaacgttatt caatttatcc ttttcctgaa tattattcag ttggtacccc tctactatat
     3541 ctttataaat actcatcggt ttgtctcctc attttccagt cgttttttat caattacttt
     3601 tagctcgaat ttgctatctt tatgcattaa gtcataaaca ctattactca ataactcaga
     3661 ttttataact gcgtatgcaa atcgctcatg tacaaataca ttaataaaat ttttatcaaa
     3721 atcaacatca attatattat taatagtatc ttttaaccta aatgcttcgc caatgaaatt
     3781 tattgataga gacagattat ttaatcgttc ttgcacttct ttagcactca tatcatttcc
     3841 taacattgca atttcatagt aatcaatacc tgtacgatag atctccaaaa ttttgaaatg
     3901 agagttttta aactcctcaa aagtttcagt tcgatttact tggaatggaa ttttcttgtg
     3961 aatgtctcct attaagtcat acgcatcaaa ctgttcataa tctctaaaat ccaaagatag
     4021 acccccagat atagcagaca gattatagtc gcttaaaata cactgtgaga tagcataaat
     4081 tgtaaaaaga tatacatcgt ctcctttaat atcttctggt aaagaaactt gaaaacattg
     4141 aacttcatca tttaatttct caaactcaat agcaggcttt atctttggca atctagcaag
     4201 aacatcccca gagacatcat tctgtaacac ctccctttta aactgcgaaa aagcaaccag
     4261 tgaactacta ggtacttcat caataactat ctttttttcg tacagttgat atactgtatc
     4321 tccaagttta tttaatgatg atgcatcaat agaatgatat ggaaaataaa atcttacttt
     4381 tttatctctt gttcccacca caataattgg aataggaatc acttctatat tatctaatat
     4441 tccttgtaat tctaactctg ttggtaaatt atttagtaca ataatattag gtgagtaatc
     4501 tccttcattc acaataccta tgctaaatcg agtttgctcc ttttcgacaa caagtctaaa
     4561 tatatcaatt ttatagctta aatatttaat aatatggtgc agcttattca attctaaata
     4621 agtcacttct tccagtgcta aattaaaacc aataacacga ttttgattgt ttttataaag
     4681 tctcttttgt gtcgggctag gagtaataat atttttcaaa taacgataat tcatttttgt
     4741 gagattatac tctaaattaa ccaagtcatg ttctttagta aaactatcgt ttggctcagt
     4801 tgaacgttct tgaaaaaatg atttatttct aatatagtcc acaatcgaat ctacactctt
     4861 tagcctataa aaatcatttt ctttaatttc aatatcaaag atatcctcaa tctctaaata
     4921 aaatctaact aattctaacg aatccaaatc tgtgatatca actctttcaa atttagatag
     4981 tacatctaaa atattttttc taacatcatc tccttgttga ctttgttttt tataataata
     5041 tatctcaagc atttttggaa catccaactt tctattctga ttgagataat aactctcaac
     5101 tttaactacc gtcggattta agtaactagg taaacttcta ataatatctt ctttaatatt
     5161 caaatcggct tcataaaata cgacaagttt cttcttataa aaaacaactc gtgatgattt
     5221 aactgattta agtttatcta caatagattt tacctcatct aattcaatac gaataccatt
     5281 tacttggact tggctatcta ttcttgaact aaataccaag ttatctcctt ggtaataaac
     5341 gtagtccccc gttacatagt acctatttga acctatcaac ttaaacttag ctttatttaa
     5401 ttcgggttgt agtctatacc cttccgttac tccattacca ccaattagaa gttctgccat
     5461 cttagaattc tctttttgag aagctatctt tagttgaacc ccaggcaaag gcttaccaat
     5521 tggaacagta ttatattttc tatctttcaa ctcatagtag gttgcataaa ttgttgtttc
     5581 tgaaggccca tataaattaa atactcgaca cccttgctga ataagccctc tcaacctatt
     5641 cgctaatgaa ctaggaaatg tctcacctgc tagacacaac gctcttaaat tctggaatac
     5701 ttctggccca ctaatatcaa taatagtttc agcaaaagac ggagataatg ataaatgagt
     5761 tatcttcttt ttctcaattg tttctcctag tcgaataata ttctgaatcc caccatcgta
     5821 acaaaccaaa gtaccacccg tatatacagg tgccaaaatc tctgttaatg aaacatcaaa
     5881 agtataggga gttgtaaata aaaattttga ttcggaagta aacttcacaa ttttataaaa
     5941 ttcttttaca agccaatcta tgttatcatc agttaaaaat acttttttag gaaccccagt
     6001 agttccagaa gtacagataa tatgtgcaat ttcattctct ttagttgtag ctacttcttg
     6061 atactcactg taactttcta attttttggg taagagcaaa agagttactg aatgattttc
     6121 aagtttaaca tccctatcac ttatcaacac gtcaaagaca acttcgctaa tacgttctaa
     6181 tgatattttg acctcaagac tatttgttat aggtaacgga attttacccg atttcattat
     6241 ccccaaaaca actggtaaaa catacttatt tttttctata taaaaaggta cagtctcttc
     6301 atcgctattg agtagtagct gcttagcaat aaaattagac atcacatcta cttcttgaaa
     6361 agtaaactct cctccgctat acataacagc aactttagaa ggatattgtt tcaccgtatc
     6421 actaaaagtt tttaatatgg tcatttctct tctccttaat ttgattgatt atgcactgtc
     6481 attcataatt tatccacaca caacaataag aatttcaaaa gcaattttca aagttggcaa
     6541 aaattttacc tttttcatca tttccctctt ttatttatca tataataaac aaaggctttt
     6601 cgtcaccgac tacagttgac aaaagagact ttcttatttt ttgcttggaa ctttcaaagc
     6661 atctttagtt ggaatataat ctttgtttcc aaagaatttt tcagccaact tagccaaagt
     6721 accatctttt tggagttctt ccaaacgttt gtttacaaat ttttgaagat ctttttgatt
     6781 atctgcg
//
