LOCUS       gnlProkkaCNGBMCEL_12    6722 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|CNGBMCEL_12.
ACCESSION   gnlProkkaCNGBMCEL_12
VERSION     gnlProkkaCNGBMCEL_12
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 13:55:36
            Original ID  :: gnl|Prokka|CNGBMCEL_12
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6722
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6722
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[278:3170]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      279..3170
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..6722
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6722
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             3..89
                     /locus_tag="ctg6_1"
                     /transl_table=11
                     /translation="MLAKLAEKFFGNKDYIPTKDALKVPSKK"
     CDS             279..3170
                     /NRPS_PKS="Domain: AMP-binding (6-388). E-value: 7.5e-65.
                     Score: 210.9. Matches aSDomain:
                     nrpspksdomains_ctg6_2_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     172.4; E-value: 2.1e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg6_2"
                     /sec_met_domain="AMP-binding (E-value: 9.9e-65, bitscore:
                     206.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-07, bitscore:
                     20.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILKTFSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLL
                     NSDEETVPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDR
                     DVKLENHSVTLLLLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNID
                     WLVKEFYKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGET
                     IEKKKITHLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRV
                     FNLYGPSETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVT
                     EGYRLQPELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQVNGIRIELDEVK
                     SIVDKLKSVKSSRVVFYKKKLVVFYEADLNIKEDIIRGLPSYLNPTVVKVESYYLNQNR
                     KLDVPKMLEIYYYKKQSQQGDDVRKNILDVLSKFERVDITDLDSLELVRFYLEIEDIFD
                     IEIKENDFYRLKSVDSIVDYIRNKSFFQERSTEPNDSFTKEHDLVNLEYNLTKMNYRYL
                     KNIITPSPTQKRLYKNNQNRVIGFNLALEEVTYLELNKLHHIIKYLSYKIDIFRLVVEK
                     EQTRFSIGIVNEGDYSPNIIVLNNLPTELELQGILDNIEVIPIPIIVVGTRDKKVRFYF
                     PYHSIDASSLNKLGDTVYQLYEKKIVIDEVPSSSLVAFSQFKREVLQNDVSGDVLARLP
                     KIKPAIEFEKLNDEVQCFQVSLPEDIKGDDVYLFTIYAISQCILSDYNLSAISGGLSLD
                     FRDYEQFDAYDLIGDIHKKIPFQVNRTETFEEFKNSHFKILEIYRTGIDYYEIAMLGND
                     MSAKEVQERLNNLSLSINFIGEAFRLKDTINNIIDVDFDKNFINVFVHERFAYAVIKSE
                     LLSNSVYDLMHKDSKFELKVIDKKRLENEETNR"
     aSDomain        297..1442
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg6_2_AMP-binding.1"
                     /evalue="7.50E-65"
                     /label="ctg6_2_AMP-binding.1"
                     /locus_tag="ctg6_2"
                     /protein_end="388"
                     /protein_start="6"
                     /score="210.9"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="FSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLLNSDEET
                     VPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDRDVKLEN
                     HSVTLLLLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNIDWLVKEF
                     YKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGETIEKKKI
                     THLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRVFNLYGP
                     SETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVTEGYRLQ
                     PELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQV"
     CDS_motif       696..752
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_2_0001"
                     /evalue="1.00E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg6_2"
                     /protein_end="158"
                     /protein_start="139"
                     /score="15.1"
                     /tool="antismash"
                     /translation="AHIICTSGTTGVPKKVFLT"
     CDS_motif       1269..1340
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_2_0002"
                     /evalue="2.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg6_2"
                     /protein_end="354"
                     /protein_start="330"
                     /score="19.7"
                     /tool="antismash"
                     /translation="ELLIGGNGVTEGYRLQPELNKAKF"
     CDS_motif       1416..1472
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_2_0003"
                     /evalue="2.60E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg6_2"
                     /protein_end="398"
                     /protein_start="379"
                     /score="20.0"
                     /tool="antismash"
                     /translation="SRIDSQVQVNGIRIELDEV"
     CDS_motif       2052..2099
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg6_2_0004"
                     /evalue="1.30E+01"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg6_2"
                     /protein_end="607"
                     /protein_start="591"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="NNQNRVIGFNLALEEV"
     CDS             3167..4813
                     /locus_tag="ctg6_3"
                     /transl_table=11
                     /translation="MSIYKDIVEGYQLNNIQEKDKLNNVLVQLNEKDDQEMINRKNFIG
                     HFTASAFVISKDNRRLLMVHHNILKRYLQPGGHIDKNDRNPLDAAKRELFEETGIDSEI
                     LTYQCAEPLNSLIPFNVSVHKIPENKLKNERSHYHYDLQYLFYIENEVDVKIDSNESSS
                     YEWIQLDNVKDMDGYKEIIKKIEKLEAASQERFLSNMLKGASFEDISCITVQHIIPSTI
                     PIIMTLQKIFGHRLLVCAKPNSVDKMVWHKLENMGVRLTLASRDEYFNVDYLGIKSKTI
                     LLDIGGYFASIAQIPNLPIECIIEDTENGIQKYENVIDQIEYPLFSVARNPLKKNEDYL
                     VGADIVFGTDYILHQKNLLMQYMQVVCIGYGKIGYGICTKLRELGIRPKVLEKDSMRTI
                     QAVRDGCDILLEKDFKNIDLIFCATGSKSLDILDFRSIKDGTFLVSATSSDDEFNYSYL
                     LDEYEEIVETSLITRYESEDNYFYLLNQGTPTNFVVNSALGNYILLVQAAILYTAKKFI
                     EDREMAIAKQVNTLSDEDNYNIAKQWLEEFC"
     CDS             4839..6047
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 278.2; E-value: 1.8e-84)"
                     /gene_kind="transport"
                     /locus_tag="ctg6_4"
                     /transl_table=11
                     /translation="MNKKEQQNTYLLVGSRIISRVGDIMFDFANNTFLSSVNIKSLMLV
                     GIYQTLENIISVIFNLFGGVLSDNFQRKRIIILTDILSGVLCLALSFISNQQWLIYAVV
                     ITNIILAFFSSFSGPAYKAFTKEVVEADNISKLNSLLESFITVVKVVVPLVSVSLYGLL
                     GLYGILRLDGITFIASGLLILFIRPILEESTGKQVFSLSKIFSDLFEGGRYLASQKEIL
                     YLVILSAIVNFFLAAYNLLLPYSNQMFPRVTVGLYGVFLGAEAVGGLIGASLSSILNKV
                     LKIKTMILYLGVSGVFLSLTPMVYCVFPSAYMLALYPALFNLFLTMFNLQFFSYIQKNV
                     DNVFLGRVFGIIFTVAILFMPIGTMTFTFLLSPKNIFNFVIVGLSIGGISLLFYRIFSK
                     RLR"
ORIGIN
        1 gtactttggc taagttggct gaaaaattct ttggaaacaa agattatatt ccaactaaag
       61 atgctttgaa agttccaagc aaaaaataag aaagtctctt ttgtcaactg tagtcggtga
      121 cgaaaagcct ttgtttatta tatgataaat aaaagaggga aatgatgaaa aaggtaaaat
      181 ttttgccaac tttgaaaatt gcttttgaaa ttcttattgt tgtgtgtgga taaattatga
      241 atgacagtgc ataatcaatc aaattaagga gaagagaaat gaccatatta aaaactttta
      301 gtgatacggt gaaacaatat ccttctaaag ttgctgttat gtatagcgga ggagagttta
      361 cttttcaaga agtagatgtg atgtctaatt ttattgctaa gcagctacta ctcaatagcg
      421 atgaagagac tgtacctttt tatatagaaa aaaataagta tgttttacca gttgttttgg
      481 ggataatgaa atcgggtaaa attccgttac ctataacaaa tagtcttgag gtcaaaatat
      541 cattagaacg tattagcgaa gttgtctttg acgtgttgat aagtgatagg gatgttaaac
      601 ttgaaaatca ttcagtaact cttttgctct tacccaaaaa attagaaagt tacagtgagt
      661 atcaagaagt agctacaact aaagagaatg aaattgcaca tattatctgt acttctggaa
      721 ctactggggt tcctaaaaaa gtatttttaa ctgatgataa catagattgg cttgtaaaag
      781 aattttataa aattgtgaag tttacttccg aatcaaaatt tttatttaca actccctata
      841 cttttgatgt ttcattaaca gagattttgg cacctgtata tacgggtggt actttggttt
      901 gttacgatgg tgggattcag aatattattc gactaggaga aacaattgag aaaaagaaga
      961 taactcattt atcattatct ccgtcttttg ctgaaactat tattgatatt agtgggccag
     1021 aagtattcca gaatttaaga gcgttgtgtc tagcaggtga gacatttcct agttcattag
     1081 cgaataggtt gagagggctt attcagcaag ggtgtcgagt atttaattta tatgggcctt
     1141 cagaaacaac aatttatgca acctactatg agttgaaaga tagaaaatat aatactgttc
     1201 caattggtaa gcctttgcct ggggttcaac taaagatagc ttctcaaaaa gagaattcta
     1261 agatggcaga acttctaatt ggtggtaatg gagtaacgga agggtataga ctacaacccg
     1321 aattaaataa agctaagttt aagttgatag gttcaaatag gtactatgta acgggggact
     1381 acgtttatta ccaaggagat aacttggtat ttagttcaag aatagatagc caagtccaag
     1441 taaatggtat tcgtattgaa ttagatgagg taaaatctat tgtagataaa cttaaatcag
     1501 ttaaatcatc acgagttgtt ttttataaga agaaacttgt cgtattttat gaagccgatt
     1561 tgaatattaa agaagatatt attagaggtt tacctagtta cttaaatccg acggtagtta
     1621 aagttgagag ttattatctc aatcagaata gaaagttgga tgttccaaaa atgcttgaga
     1681 tatattatta taaaaaacaa agtcaacaag gagatgatgt tagaaaaaat attttagatg
     1741 tactatctaa atttgaaaga gttgatatca cagatttgga ttcgttagaa ttagttagat
     1801 tttatttaga gattgaggat atctttgata ttgaaattaa agaaaatgat ttttataggc
     1861 taaagagtgt agattcgatt gtggactata ttagaaataa atcatttttt caagaacgtt
     1921 caactgagcc aaacgatagt tttactaaag aacatgactt ggttaattta gagtataatc
     1981 tcacaaaaat gaattatcgt tatttgaaaa atattattac tcctagcccg acacaaaaga
     2041 gactttataa aaacaatcaa aatcgtgtta ttggttttaa tttagcactg gaagaagtga
     2101 cttatttaga attgaataag ctgcaccata ttattaaata tttaagctat aaaattgata
     2161 tatttagact tgttgtcgaa aaggagcaaa ctcgatttag cataggtatt gtgaatgaag
     2221 gagattactc acctaatatt attgtactaa ataatttacc aacagagtta gaattacaag
     2281 gaatattaga taatatagaa gtgattccta ttccaattat tgtggtggga acaagagata
     2341 aaaaagtaag attttatttt ccatatcatt ctattgatgc atcatcatta aataaacttg
     2401 gagatacagt atatcaactg tacgaaaaaa agatagttat tgatgaagta cctagtagtt
     2461 cactggttgc tttttcgcag tttaaaaggg aggtgttaca gaatgatgtc tctggggatg
     2521 ttcttgctag attgccaaag ataaagcctg ctattgagtt tgagaaatta aatgatgaag
     2581 ttcaatgttt tcaagtttct ttaccagaag atattaaagg agacgatgta tatcttttta
     2641 caatttatgc tatctcacag tgtattttaa gcgactataa tctgtctgct atatctgggg
     2701 gtctatcttt ggattttaga gattatgaac agtttgatgc gtatgactta ataggagaca
     2761 ttcacaagaa aattccattc caagtaaatc gaactgaaac ttttgaggag tttaaaaact
     2821 ctcatttcaa aattttggag atctatcgta caggtattga ttactatgaa attgcaatgt
     2881 taggaaatga tatgagtgct aaagaagtgc aagaacgatt aaataatctg tctctatcaa
     2941 taaatttcat tggcgaagca tttaggttaa aagatactat taataatata attgatgttg
     3001 attttgataa aaattttatt aatgtatttg tacatgagcg atttgcatac gcagttataa
     3061 aatctgagtt attgagtaat agtgtttatg acttaatgca taaagatagc aaattcgagc
     3121 taaaagtaat tgataaaaaa cgactggaaa atgaggagac aaaccgatga gtatttataa
     3181 agatatagta gaggggtacc aactgaataa tattcaggaa aaggataaat tgaataacgt
     3241 tttggtacag cttaatgaaa aagatgatca agagatgata aatagaaaga atttcattgg
     3301 gcattttaca gcatcagcat ttgttatttc aaaagataac aggcgtttat tgatggttca
     3361 ccataatatt ttaaaaagat acctacagcc tggggggcat attgataaaa atgatagaaa
     3421 cccgctagat gcagcgaaac gtgagctgtt tgaggagact gggatagatt ctgaaatatt
     3481 gacgtatcaa tgtgcagaac cattgaatag cttgatacct tttaatgttt ctgtgcataa
     3541 gataccagaa aataaattga agaatgagcg ttcccactac cattatgact tgcaatattt
     3601 attttatatt gaaaatgagg ttgatgtgaa aattgacagc aacgaatcga gttcctatga
     3661 gtggattcag ctagataatg taaaggacat ggacggctat aaggaaatca ttaagaagat
     3721 tgaaaaactt gaagcagctt ctcaagaacg ttttttatct aatatgctga aaggtgcatc
     3781 gtttgaagac atatcatgta ttactgtaca acatattatt ccaagtacaa taccgattat
     3841 catgacattg caaaaaatat ttgggcatcg tttgttagtg tgtgctaaac caaactctgt
     3901 tgataagatg gtatggcaca agctagaaaa tatgggggta agattaacat tagcttcaag
     3961 ggatgaatat tttaatgtag attatctggg gataaagagt aaaacaattt tattagacat
     4021 tggtgggtat tttgcctcaa ttgctcagat tccaaactta cctatcgagt gtatcattga
     4081 agatacagaa aatgggattc aaaaatatga gaatgttatt gatcaaatag aatatccgtt
     4141 attttctgtc gctagaaatc ccctgaagaa gaatgaggat tacttagttg gtgcggatat
     4201 tgtttttggg acagattata tattacatca aaaaaattta ttaatgcaat atatgcaagt
     4261 ggtttgtatt ggatatggga aaatcggtta cggcatctgt accaaattaa gagaacttgg
     4321 tattagaccg aaggtgctgg aaaaagatag catgagaact attcaagcgg tacgtgatgg
     4381 ttgcgacatt ttgctagaaa aagatttcaa gaatattgat ttgatttttt gtgcgaccgg
     4441 ttcaaaaagt ctagatattt tagattttcg ctctatcaaa gatggaacct tcctagtctc
     4501 tgcaacatct agtgatgatg aatttaatta tagctattta ttggatgaat atgaagaaat
     4561 agtcgaaact tcattaatca ctagatatga aagtgaagac aactatttct atctgttaaa
     4621 tcaaggaaca ccaactaatt ttgtagtaaa ctccgctttg ggaaattata ttttattagt
     4681 ccaggcagcc attctatata cagctaagaa gtttattgaa gatagagaaa tggctatagc
     4741 taagcaagta aacactcttt cggatgagga taactataat attgcgaagc aatggttaga
     4801 agagttctgc taatgaacaa atatctgagg agtttatttt gaataaaaaa gaacaacaaa
     4861 atacatattt acttgtaggg agccgtatta tttctcgtgt tggagatatt atgtttgact
     4921 ttgcgaataa cactttttta tcgagtgtaa atattaagtc acttatgtta gttggtattt
     4981 atcagacatt agaaaacatc atcagtgtga tttttaatct ttttggtggt gttctgtctg
     5041 ataactttca aagaaaacgg attatcattt taacagatat tttaagcgga gtattgtgtc
     5101 ttgccttatc ttttatttct aatcagcagt ggttgattta tgctgtggtt atcacaaaca
     5161 ttatattagc ttttttctca tcattttcag gccctgctta taaggctttt actaaagaag
     5221 tggtggaagc agataatatt tcaaaactaa actcattact agaatcgttt ataacggtag
     5281 ttaaagtcgt tgttcccctg gtatcggtat ctctatacgg tttactagga ttatatggta
     5341 ttttacgtct agatgggata acatttattg catctgggtt gcttattctc tttattcgtc
     5401 ccatacttga agaaagtact gggaaacagg tgttttcatt atcgaaaatc ttttcagatc
     5461 tttttgaagg aggaaggtat ctagctagtc aaaaggaaat tttgtacttg gttattttat
     5521 ctgcgattgt taatttcttt ttagcagctt ataatctgtt gttaccatat agcaatcaga
     5581 tgttcccaag agttaccgtt ggcttatacg gtgttttcct aggagcagaa gcagtaggtg
     5641 gtcttattgg agcgtcttta agcagtattc tcaataaagt tttgaaaata aaaacaatga
     5701 ttttatatct tggagtatca ggtgtttttc tatctttgac acctatggta tactgtgttt
     5761 ttccaagtgc ttatatgctt gcgttatatc ctgctttatt caacttgttt ttgactatgt
     5821 tcaacttaca gtttttttca tatatccaaa agaatgtgga taatgtcttt cttggtagag
     5881 tttttgggat tatttttact gttgcaattt tatttatgcc cattgggaca atgacattta
     5941 cttttctttt aagccctaaa aatatcttta attttgttat cgttggttta tctataggag
     6001 gtatttcgct tctcttttat aggattttta gcaaaagatt gaggtaaatt ttcagagtaa
     6061 ttttagctcc gatggcgtag taaaattgct tagtaaagtc acaatttata tacttgttag
     6121 ggcaaccatt acacacataa ggtaatcgtt ttagaagtgg gcgggcctca cattttgagt
     6181 gttgattgat tccttgatgg taaggtgttt acatactttt ttagagacag tagatgggtc
     6241 gccgattagt ttagaaatag ctctaaatgt cttgttcgtt tctcataaaa gtcagcgata
     6301 ttgcagggat tggtatgact agctgaagcg atgttgtgaa tgtacttgaa caagatttta
     6361 ctggcatagg gattccctcg tttagtgatg tgttccttag cgagaaagtt cccagattca
     6421 tagtgtctca ggtcaatgcc aataaaagcg ttgatttgat tggtatactg cgacgaatat
     6481 ctcccaattc gccaatgata gatgtcgctg tggtttctgc gatgccagga attgaccgta
     6541 agatgtcata ctctggtaaa ggctgagcta gagctaccat gtcgtttaag acaacccgtc
     6601 tgcgttcaga aagacgaagc aattcggctc tttgtcaaac aattgatatt tttaggtgat
     6661 agtattttct tatcactttg attatgttta agtattagtt aagcttagtg aattctgtta
     6721 ca
//
