LOCUS       gnlProkkaDKGCIGHF_109   6791 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|DKGCIGHF_109.
ACCESSION   gnlProkkaDKGCIGHF_109
VERSION     gnlProkkaDKGCIGHF_109
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:10:32
            Original ID  :: gnl|Prokka|DKGCIGHF_109
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6791
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             1..156
                     /locus_tag="ctg66_1"
                     /transl_table=11
                     /translation="MADNQKDLQKFVNKRLEELQKDGTLAKLAEKFFGNKDYIPTKDAL
                     KVPSKK"
     protocluster    1..6791
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[345:3237]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      346..3237
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..6791
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6791
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             346..3237
                     /NRPS_PKS="Domain: AMP-binding (6-388). E-value: 7.5e-65.
                     Score: 210.9. Matches aSDomain:
                     nrpspksdomains_ctg66_2_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     172.5; E-value: 2e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg66_2"
                     /sec_met_domain="AMP-binding (E-value: 9.9e-65, bitscore:
                     206.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-07, bitscore:
                     20.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILKTFSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLL
                     NSDEETVPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDR
                     DVKLENHSVTLLLLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNID
                     WLVKEFYKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGET
                     IEKKKITHLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRV
                     FNLYGPSETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVT
                     EGYRLQPELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQVNGIRIELDEVK
                     SIVDKLKSVKSSRVVFYKKKLVVFYEADLNIKEDIIRSLPSYLNPTVVKVESYYLNQNR
                     KLDVPKMLEIYYYKKQSQQGDDVRKNILDVLSKFERVDITDLDSLELVRFYLEIEDIFD
                     IEIKENDFYRLKSVDSIVDYIRNKSFFQERSTEPNDSFTKEHDLVNLEYNLTKMNYRYL
                     KNIITPSPTQKRLYKNNQNRVIGFNLALEEVTYLELNKLHHIIKYLSYKIDIFRLVVEK
                     EQTRFSIGIVNEGDYSPNIIVLNNLPTELELQGILDNIEVIPIPIIVVGTRDKKVRFYF
                     PYHSIDASSLNKLGDTVYQLYEKKIVIDEVPSSSLVAFSQFKREVLQNDVSGDVLARLP
                     KIKPAIEFEKLNDEVQCFQVSLPEDIKGDDVYLFTIYAISQCILSDYNLSAISGGLSLD
                     FRDYEQFDAYDLIGDIHKKIPFQVNRTETFEEFKNSHFKILEIYRTGIDYYEIAMLGND
                     MSAKEVQERLNNLSLSINFIGEAFRLKDTINNIIDVDFDKNFINVFVHERFAYAVIKSE
                     LLSNSVYDLMHKDSKFELKVIDKKRLENEETNR"
     aSDomain        364..1509
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg66_2_AMP-binding.1"
                     /evalue="7.50E-65"
                     /label="ctg66_2_AMP-binding.1"
                     /locus_tag="ctg66_2"
                     /protein_end="388"
                     /protein_start="6"
                     /score="210.9"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="FSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLLNSDEET
                     VPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDRDVKLEN
                     HSVTLLLLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNIDWLVKEF
                     YKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGETIEKKKI
                     THLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRVFNLYGP
                     SETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVTEGYRLQ
                     PELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQV"
     CDS_motif       763..819
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg66_2_0001"
                     /evalue="1.00E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg66_2"
                     /protein_end="158"
                     /protein_start="139"
                     /score="15.1"
                     /tool="antismash"
                     /translation="AHIICTSGTTGVPKKVFLT"
     CDS_motif       1336..1407
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg66_2_0002"
                     /evalue="2.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg66_2"
                     /protein_end="354"
                     /protein_start="330"
                     /score="19.7"
                     /tool="antismash"
                     /translation="ELLIGGNGVTEGYRLQPELNKAKF"
     CDS_motif       1483..1539
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg66_2_0003"
                     /evalue="2.60E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg66_2"
                     /protein_end="398"
                     /protein_start="379"
                     /score="20.0"
                     /tool="antismash"
                     /translation="SRIDSQVQVNGIRIELDEV"
     CDS_motif       2119..2166
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg66_2_0004"
                     /evalue="1.30E+01"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg66_2"
                     /protein_end="607"
                     /protein_start="591"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="NNQNRVIGFNLALEEV"
     CDS             3234..4880
                     /locus_tag="ctg66_3"
                     /transl_table=11
                     /translation="MSIYKDIVEGYQLNNIQEKDKLNNVLVQLNEKDDQEMINRKNFIG
                     HFTASAFVISKDNRRLLMVHHNILKRYLQPGGHIDKNDRNPLDAAKRELFEETGIDSEI
                     LTYQCAEPLNSLIPFNVSVHKIPENKLKNERSHYHYDLQYLFYIENEVDVKIDSNESSS
                     YEWIQLDNVKDMDGYKEIIKKIEKLEAASQERFLSNMLKGASFEDISCITVQHIIPSTI
                     PIIMTLQKIFGHRLLVCAKPNSVDKMVWHKLENMGVRLTLASRDEYFNVDYLGIKSKTI
                     LLDIGGYFASIAQIPNLPIECIIEDTENGIQKYENVIDQIEYPLFSVARNPLKKNEDYL
                     VGADIVFGTDYILHQKNLLMQYMQVVCIGYGKIGYGICTKLRELGIRPKVLEKDSMRTI
                     QAVRDGCDILLEKDFKNIDLIFCATGSKSLDILDFRSIKDGTFLVSATSSDDEFNYSYL
                     LDEYEEIVETSLITRYESEDNYFYLLNQGTPTNFVVNSALGNYILLVQAAILYTAKKFI
                     EDREMAIAKQVNTLSDEDNYNIAKQWLEEFC"
     CDS             4906..6114
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 278.7; E-value: 1.3e-84)"
                     /gene_kind="transport"
                     /locus_tag="ctg66_4"
                     /transl_table=11
                     /translation="MNKKEQQNTYLLVGSRIISRVGDIMFDFANNTFLSSVNVKSLMLV
                     GIYQTLENIISVIFNLFGGVLSDNFQRKRIIILTDILSGVLCLALSFISNQQWLIYAVV
                     ITNIILAFFSSFSGPAYKAFTKEVVEADNISKLNSLLESFITVVKVVVPLVSVSLYGLL
                     GLYGILRLDGITFIASGLLILFIRPILEESTGKQVFSLSKIFSDLFEGGRYLASQKEIL
                     YLVILSAIVNFFLAAYNLLLPYSNQMFPRVTVGLYGVFLGAEAVGGLIGASLSSILNKV
                     LKIKTMILYLGVSGVFLSLTPMVYCVFPSAYMLALYPALFNLFLTMFNLQFFSYIQKNV
                     DNVFLGRVFGIIFTVAILFMPIGTMTFTFLLSPKNIFNFVIVGLSIGGISLLFYRIFSK
                     RLR"
ORIGIN
        1 ttcgcagata atcaaaaaga tcttcaaaaa tttgtaaaca aacgtttgga agaactccaa
       61 aaagatggta ctttggctaa gttggctgaa aaattctttg gaaacaaaga ttatattcca
      121 actaaagatg ctttgaaagt tccaagcaaa aaataagaaa gtctcttttg tcaactgtag
      181 tcggtgacga aaagcctttg tttattatat gataaataaa agagggaaat gatgaaaaag
      241 gtaaaatttt tgccaacttt gaaaattgct tttgaaattc ttattgttgt gtgtggataa
      301 attatgaatg acagtgcata atcaatcaaa ttaaggagaa gagaaatgac catattaaaa
      361 acttttagtg atacggtgaa acaatatcct tctaaagttg ctgttatgta tagcggagga
      421 gagtttactt ttcaagaagt agatgtgatg tctaatttta ttgctaagca gctactactc
      481 aatagcgatg aagagactgt acctttttat atagaaaaaa ataagtatgt tttaccagtt
      541 gttttgggga taatgaaatc gggtaaaatt ccgttaccta taacaaatag tcttgaggtc
      601 aaaatatcat tagaacgtat tagcgaagtt gtctttgacg tgttgataag tgatagggat
      661 gttaaacttg aaaatcattc agtaactctt ttgctcttac ccaaaaaatt agaaagttac
      721 agtgagtatc aagaagtagc tacaactaaa gagaatgaaa ttgcacatat tatctgtact
      781 tctggaacta ctggggttcc taaaaaagta tttttaactg atgataacat agattggctt
      841 gtaaaagaat tttataaaat tgtgaagttt acttccgaat caaaattttt atttacaact
      901 ccctatactt ttgatgtttc attaacagag attttggcac ctgtatatac gggtggtact
      961 ttggtttgtt acgatggtgg gattcagaat attattcgac taggagaaac aattgagaaa
     1021 aagaagataa ctcatttatc attatctccg tcttttgctg aaactattat tgatattagt
     1081 gggccagaag tattccagaa tttaagagcg ttgtgtctag caggtgagac atttcctagt
     1141 tcattagcga ataggttgag agggcttatt cagcaagggt gtcgagtatt taatttatat
     1201 gggccttcag aaacaacaat ttatgcaacc tactatgagt tgaaagatag aaaatataat
     1261 actgttccaa ttggtaagcc tttgcctggg gttcaactaa agatagcttc tcaaaaagag
     1321 aattctaaga tggcagaact tctaattggt ggtaatggag taacggaagg gtatagacta
     1381 caacccgaat taaataaagc taagtttaag ttgataggtt caaataggta ctatgtaacg
     1441 ggggactacg tttattacca aggagataac ttggtattta gttcaagaat agatagccaa
     1501 gtccaagtaa atggtattcg tattgaatta gatgaggtaa aatctattgt agataaactt
     1561 aaatcagtta aatcatcacg agttgttttt tataagaaga aacttgtcgt attttatgaa
     1621 gccgatttga atattaaaga agatattatt agaagtttac ctagttactt aaatccgacg
     1681 gtagttaaag ttgagagtta ttatctcaat cagaatagaa agttggatgt tccaaaaatg
     1741 cttgagatat attattataa aaaacaaagt caacaaggag atgatgttag aaaaaatatt
     1801 ttagatgtac tatctaaatt tgaaagagtt gatatcacag atttggattc gttagaatta
     1861 gttagatttt atttagagat tgaggatatc tttgatattg aaattaaaga aaatgatttt
     1921 tataggctaa agagtgtaga ttcgattgtg gactatatta gaaataaatc attttttcaa
     1981 gaacgttcaa ctgagccaaa cgatagtttt actaaagaac atgacttggt taatttagag
     2041 tataatctca caaaaatgaa ttatcgttat ttgaaaaata ttattactcc tagcccgaca
     2101 caaaagagac tttataaaaa caatcaaaat cgtgttattg gttttaattt agcactggaa
     2161 gaagtgactt atttagaatt gaataagctg caccatatta ttaaatattt aagctataaa
     2221 attgatatat ttagacttgt tgtcgaaaag gagcaaactc gatttagcat aggtattgtg
     2281 aatgaaggag attactcacc taatattatt gtactaaata atttaccaac agagttagaa
     2341 ttacaaggaa tattagataa tatagaagtg attcctattc caattattgt ggtgggaaca
     2401 agagataaaa aagtaagatt ttattttcca tatcattcta ttgatgcatc atcattaaat
     2461 aaacttggag atacagtata tcaactgtac gaaaaaaaga tagttattga tgaagtacct
     2521 agtagttcac tggttgcttt ttcgcagttt aaaagggagg tgttacagaa tgatgtctct
     2581 ggggatgttc ttgctagatt gccaaagata aagcctgcta ttgagtttga gaaattaaat
     2641 gatgaagttc aatgttttca agtttcttta ccagaagata ttaaaggaga cgatgtatat
     2701 ctttttacaa tttatgctat ctcacagtgt attttaagcg actataatct gtctgctata
     2761 tctgggggtc tatctttgga ttttagagat tatgaacagt ttgatgcgta tgacttaata
     2821 ggagacattc acaagaaaat tccattccaa gtaaatcgaa ctgaaacttt tgaggagttt
     2881 aaaaactctc atttcaaaat tttggagatc tatcgtacag gtattgatta ctatgaaatt
     2941 gcaatgttag gaaatgatat gagtgctaaa gaagtgcaag aacgattaaa taatctgtct
     3001 ctatcaataa atttcattgg cgaagcattt aggttaaaag atactattaa taatataatt
     3061 gatgttgatt ttgataaaaa ttttattaat gtatttgtac atgagcgatt tgcatacgca
     3121 gttataaaat ctgagttatt gagtaatagt gtttatgact taatgcataa agatagcaaa
     3181 ttcgagctaa aagtaattga taaaaaacga ctggaaaatg aggagacaaa ccgatgagta
     3241 tttataaaga tatagtagag gggtaccaac tgaataatat tcaggaaaag gataaattga
     3301 ataacgtttt ggtacagctt aatgaaaaag atgatcaaga gatgataaat agaaagaatt
     3361 tcattgggca ttttacagca tcagcatttg ttatttcaaa agataacagg cgtttattga
     3421 tggttcacca taatatttta aaaagatacc tacagcctgg ggggcatatt gataaaaatg
     3481 atagaaaccc gctagatgca gcgaaacgtg agctgtttga ggagactggg atagattctg
     3541 aaatattgac gtatcaatgt gcagaaccat tgaatagctt gatacctttt aatgtttctg
     3601 tgcataagat accagaaaat aaattgaaga atgagcgttc ccactaccat tatgacttgc
     3661 aatatttatt ttatattgaa aatgaggttg atgtgaaaat tgacagcaac gaatcgagtt
     3721 cctatgagtg gattcagcta gataatgtaa aggacatgga cggctataag gaaatcatta
     3781 agaagattga aaaacttgaa gcagcttctc aagaacgttt tttatctaat atgctgaaag
     3841 gtgcatcgtt tgaagacata tcatgtatta ctgtacaaca tattattcca agtacaatac
     3901 cgattatcat gacattgcaa aaaatatttg ggcatcgttt gttagtgtgt gctaaaccaa
     3961 actctgttga taagatggta tggcacaagc tagaaaatat gggggtaaga ttaacattag
     4021 cttcaaggga tgaatatttt aatgtagatt atctggggat aaagagtaaa acaattttat
     4081 tagacattgg tgggtatttt gcctcaattg ctcagattcc aaacttacct atcgagtgta
     4141 tcattgaaga tacagaaaat gggattcaaa aatatgagaa tgttattgat caaatagaat
     4201 atccgttatt ttctgtcgct agaaatcccc tgaagaagaa tgaggattac ttagttggtg
     4261 cggatattgt ttttgggaca gattatatat tacatcaaaa aaatttatta atgcaatata
     4321 tgcaagtggt ttgtattgga tatgggaaaa tcggttacgg catctgtacc aaattaagag
     4381 aacttggtat tagaccgaag gtgctggaaa aagatagcat gagaactatt caagcggtac
     4441 gtgatggttg cgacattttg ctagaaaaag atttcaagaa tattgatttg attttttgtg
     4501 cgaccggttc aaaaagtcta gatattttag attttcgctc tatcaaagat ggaaccttcc
     4561 tagtctctgc aacatctagt gatgatgaat ttaattatag ctatttattg gatgaatatg
     4621 aagaaatagt cgaaacttca ttaatcacta gatatgaaag tgaagacaac tatttctatc
     4681 tgttaaatca aggaacacca actaattttg tagtaaactc cgctttggga aattatattt
     4741 tattagtcca ggcagccatt ctatatacag ctaagaagtt tattgaagat agagaaatgg
     4801 ctatagctaa gcaagtaaac actctttcgg atgaggataa ctataatatt gcgaagcaat
     4861 ggttagaaga gttctgctaa tgaacaaata tctgaggagt ttattttgaa taaaaaagaa
     4921 caacaaaata catatttact tgtagggagc cgtattattt ctcgtgttgg agatattatg
     4981 tttgactttg cgaataacac ttttttatcg agtgtaaatg ttaagtcact tatgttagtt
     5041 ggtatttatc agacattaga aaacatcatc agtgtgattt ttaatctttt tggtggtgtt
     5101 ctgtctgata actttcaaag aaaacggatt atcattttaa cagatatttt aagcggagta
     5161 ttgtgtcttg ccttatcttt tatttctaat cagcagtggt tgatttatgc tgtggttatc
     5221 acaaacatta tattagcttt tttctcatca ttttcaggcc ctgcttataa ggcttttact
     5281 aaagaagtgg tggaagcaga taatatttca aaactaaact cattactaga atcgtttata
     5341 acggtagtta aagtcgttgt tcccctggta tcggtatctc tatacggttt actaggatta
     5401 tatggtattt tacgtctaga tgggataaca tttattgcat ctgggttgct tattctcttt
     5461 attcgtccca tacttgaaga aagtactggg aaacaggtgt tttcattatc gaaaatcttt
     5521 tcagatcttt ttgaaggagg aaggtatcta gctagtcaaa aggaaatttt gtacttggtt
     5581 attttatctg cgattgttaa tttcttttta gcagcttata atctgttgtt accatatagc
     5641 aatcagatgt tcccaagagt taccgttggc ttatacggtg ttttcctagg agcagaagca
     5701 gtaggtggtc ttattggagc gtctttaagc agtattctca ataaagtttt gaaaataaaa
     5761 acaatgattt tatatcttgg agtatcaggt gtttttctat ctttgacacc tatggtatac
     5821 tgtgtttttc caagtgctta tatgcttgcg ttatatcctg ctttattcaa cttgtttttg
     5881 actatgttca acttacagtt tttttcatat atccaaaaga atgtggataa tgtctttctt
     5941 ggtagagttt ttgggattat ttttactgtt gcaattttat ttatgcccat tgggacaatg
     6001 acatttactt ttcttttaag ccctaaaaat atctttaatt ttgttatcgt tggtttatct
     6061 ataggaggta tttcgcttct cttttatagg atttttagca aaagattgag gtaaattttc
     6121 agagtaattt tagctccgat ggcgtagtaa aattgcttag taaagtcaca atttatatac
     6181 ttgttagggc aaccattaca cacataaggt aatcgtttta gaagtgggcg ggcctcacat
     6241 tttgagtgtt gattgattcc ttgatggtaa ggtgtttaca tactttttta gagacagtag
     6301 atgggtcgcc gattagttta gaaatagctc taaatgtctt gttcgtttct cataaaagtc
     6361 agcgatattg cagggattgg tatgactagc tgaagcgatg ttgtgaatgt acttgaacaa
     6421 gattttactg gcatagggat tccctcgttt agtgatgtgt tccttagcga gaaagttccc
     6481 agattcatag tgtctcaggt caatgccaat aaaagcgttg atttgattgg tatactgcga
     6541 cgaatatctc ccaattcgcc aatgatagat gtcgctgtgg tttctgcgat gccaggaatt
     6601 gaccgtaaga tgtcatactc tggtaaaggc tgagctagag ctaccatgtc gtttaagaca
     6661 acccgtctgc gttcagaaag acgaagcaat tcggctcttt gtcaaacaat tgatattttt
     6721 aggtgatagt attttcttat cactttgatt atgtttaagt attagttaag cttagtgaat
     6781 tctgttacaa t
//
