LOCUS       gnlProkkaEKMEGDEP_19    6821 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|EKMEGDEP_19.
ACCESSION   gnlProkkaEKMEGDEP_19
VERSION     gnlProkkaEKMEGDEP_19
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:11:23
            Original ID  :: gnl|Prokka|EKMEGDEP_19
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 6821
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..6821
                     /aStool="rule-based-clusters"
                     /category="NRPS"
                     /contig_edge="True"
                     /core_location="[3584:6476]"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3585..6476
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="0"
                     /detection_rule="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /neighbourhood="20000"
                     /product="NRPS-like"
                     /protocluster_number="1"
     cand_cluster    1..6821
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="cds((PP-binding or NAD_binding_4) and
                     (AMP-binding or A-OX))"
                     /kind="single"
                     /product="NRPS-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..6821
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="NRPS-like"
                     /region_number="1"
                     /rules="cds((PP-binding or NAD_binding_4) and (AMP-binding
                     or A-OX))"
                     /tool="antismash"
     CDS             complement(708..1916)
                     /gene_functions="transport (smcogs) SMCOG1020:major
                     facilitator transporter (Score: 278.7; E-value: 1.3e-84)"
                     /gene_kind="transport"
                     /locus_tag="ctg14_1"
                     /transl_table=11
                     /translation="MNKKEQQNTYLLVGSRIISRVGDIMFDFANNTFLSSVNVKSLMLV
                     GIYQTLENIISVIFNLFGGVLSDNFQRKRIIILTDILSGVLCLALSFISNQQWLIYAVV
                     ITNIILAFFSSFSGPAYKAFTKEVVEADNISKLNSLLESFITVVKVVVPLVSVSLYGLL
                     GLYGILRLDGITFIASGLLILFIRPILEESTGKQVFSLSKIFSDLFEGGRYLASQKEIL
                     YLVILSAIVNFFLAAYNLLLPYSNQMFPRVTVGLYGVFLGAEAVGGLIGASLSSILNKV
                     LKIKTMILYLGVSGVFLSLTPMVYCVFPSAYMLALYPALFNLFLTMFNLQFFSYIQKNV
                     DNVFLGRVFGIIFTVAILFMPIGTMTFTFLLSPKNIFNFVIVGLSIGGISLLFYRIFSK
                     RLR"
     CDS             complement(1942..3588)
                     /locus_tag="ctg14_2"
                     /transl_table=11
                     /translation="MSIYKDIVEGYQLNNIQEKDKLNNVLVQLNEKDDQEMINRKNFIG
                     HFTASAFVISKDNRRLLMVHHNILKRYLQPGGHIDKNDRNPLDAAKRELFEETGIDSEI
                     LTYQCAEPLNSLIPFNVSVHKIPENKLKNERSHYHYDLQYLFYIENEVDVKIDSNESSS
                     YEWIQLDNVKDMDGYKEIIKKIEKLEAASQERFLSNMLKGASFEDISCITVQHIIPSTI
                     PIIMTLQKIFGHRLLVCAKPNSVDKMVWHKLENMGVRLTLASRDEYFNVDYLGIKSKTI
                     LLDIGGYFASIAQIPNLPIECIIEDTENGIQKYENVIDQIEYPLFSVARNPLKKNEDYL
                     VGADIVFGTDYILHQKNLLMQYMQVVCIGYGKIGYGICTKLRELGIRPKVLEKDSMRTI
                     QAVRDGCDILLEKDFKNIDLIFCATGSKSLDILDFRSIKDGTFLVSATSSDDEFNYSYL
                     LDEYEEIVETSLITRYESEDNYFYLLNQGTPTNFVVNSALGNYILLVQAAILYTAKKFI
                     EDREMAIAKQVNTLSDEDNYNIAKQWLEEFC"
     CDS             complement(3585..6476)
                     /NRPS_PKS="Domain: AMP-binding (6-388). E-value: 7.5e-65.
                     Score: 210.9. Matches aSDomain:
                     nrpspksdomains_ctg14_3_AMP-binding.1"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: AMP-binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     NRPS-like: PP-binding"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1002:AMP-dependent synthetase and ligase (Score:
                     172.5; E-value: 2e-52)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg14_3"
                     /sec_met_domain="AMP-binding (E-value: 9.9e-65, bitscore:
                     206.7, seeds: 400, tool: rule-based-clusters)"
                     /sec_met_domain="PP-binding (E-value: 1.5e-07, bitscore:
                     20.1, seeds: 164, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTILKTFSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLL
                     NSDEETVPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDR
                     DVKLENHSVTLLLLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNID
                     WLVKEFYKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGET
                     IEKKKITHLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRV
                     FNLYGPSETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVT
                     EGYRLQPELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQVNGIRIELDEVK
                     SIVDKLKSVKSSRVVFYKKKLVVFYEADLNIKEDIIRSLPSYLNPTVVKVESYYLNQNR
                     KLDVPKMLEIYYYKKQSQQGDDVRKNILDVLSKFERVDITDLDSLELVRFYLEIEDIFD
                     IEIKENDFYRLKSVDSIVDYIRNKSFFQERSTEPNDSFTKEHDLVNLEYNLTKMNYRYL
                     KNIITPSPTQKRLYKNNQNRVIGFNLALEEVTYLELNKLHHIIKYLSYKIDIFRLVVEK
                     EQTRFSIGIVNEGDYSPNIIVLNNLPTELELQGILDNIEVIPIPIIVVGTRDKKVRFYF
                     PYHSIDASSLNKLGDTVYQLYEKKIVIDEVPSSSLVAFSQFKREVLQNDVSGDVLARLP
                     KIKPAIEFEKLNDEVQCFQVSLPEDIKGDDVYLFTIYAISQCILSDYNLSAISGGLSLD
                     FRDYEQFDAYDLIGDIHKKIPFQVNRTETFEEFKNSHFKILEIYRTGIDYYEIAMLGND
                     MSAKEVQERLNNLSLSINFIGEAFRLKDTINNIIDVDFDKNFINVFVHERFAYAVIKSE
                     LLSNSVYDLMHKDSKFELKVIDKKRLENEETNR"
     CDS_motif       complement(4656..4703)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_3_0004"
                     /evalue="1.30E+01"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg14_3"
                     /protein_end="607"
                     /protein_start="591"
                     /score="-0.8"
                     /tool="antismash"
                     /translation="NNQNRVIGFNLALEEV"
     CDS_motif       complement(5283..5339)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_3_0003"
                     /evalue="2.60E-06"
                     /label="NRPS-A_a8"
                     /locus_tag="ctg14_3"
                     /protein_end="398"
                     /protein_start="379"
                     /score="20.0"
                     /tool="antismash"
                     /translation="SRIDSQVQVNGIRIELDEV"
     aSDomain        complement(5313..6458)
                     /aSDomain="AMP-binding"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg14_3_AMP-binding.1"
                     /evalue="7.50E-65"
                     /label="ctg14_3_AMP-binding.1"
                     /locus_tag="ctg14_3"
                     /protein_end="388"
                     /protein_start="6"
                     /score="210.9"
                     /specificity="substrate consensus: Ala"
                     /tool="antismash"
                     /translation="FSDTVKQYPSKVAVMYSGGEFTFQEVDVMSNFIAKQLLLNSDEET
                     VPFYIEKNKYVLPVVLGIMKSGKIPLPITNSLEVKISLERISEVVFDVLISDRDVKLEN
                     HSVTLLLLPKKLESYSEYQEVATTKENEIAHIICTSGTTGVPKKVFLTDDNIDWLVKEF
                     YKIVKFTSESKFLFTTPYTFDVSLTEILAPVYTGGTLVCYDGGIQNIIRLGETIEKKKI
                     THLSLSPSFAETIIDISGPEVFQNLRALCLAGETFPSSLANRLRGLIQQGCRVFNLYGP
                     SETTIYATYYELKDRKYNTVPIGKPLPGVQLKIASQKENSKMAELLIGGNGVTEGYRLQ
                     PELNKAKFKLIGSNRYYVTGDYVYYQGDNLVFSSRIDSQVQV"
     CDS_motif       complement(5415..5486)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_3_0002"
                     /evalue="2.80E-06"
                     /label="NRPS-A_a6"
                     /locus_tag="ctg14_3"
                     /protein_end="354"
                     /protein_start="330"
                     /score="19.7"
                     /tool="antismash"
                     /translation="ELLIGGNGVTEGYRLQPELNKAKF"
     CDS_motif       complement(6003..6059)
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg14_3_0001"
                     /evalue="1.00E-04"
                     /label="NRPS-A_a3"
                     /locus_tag="ctg14_3"
                     /protein_end="158"
                     /protein_start="139"
                     /score="15.1"
                     /tool="antismash"
                     /translation="AHIICTSGTTGVPKKVFLT"
     CDS             complement(6666..6821)
                     /locus_tag="ctg14_4"
                     /transl_table=11
                     /translation="MADNQKDLQKFVNKRLEELQKDGTLAKLAEKFFGNKDYIPTKDAL
                     KVPSKK"
ORIGIN
        1 ataatactct cctttgagat tgattttttt attgtaacag aattcactaa gcttaactaa
       61 tacttaaaca taatcaaagt gataagaaaa tactatcacc taaaaatatc aattgtttga
      121 caaagagccg aattgcttcg tctttctgaa cgcagacggg ttgtcttaaa cgacatggta
      181 gctctagctc agcctttacc agagtatgac atcttacggt caattcctgg catcgcagaa
      241 accacagcga catctatcat tggcgaattg ggagatattc gtcgcagtat accaatcaaa
      301 tcaacgcttt tattggcatt gacctgagac actatgaatc tgggaacttt ctcgctaagg
      361 aacacatcac taaacgaggg aatccctatg ccagtaaaat cttgttcaag tacattcaca
      421 acatcgcttc agctagtcat accaatccct gcaatatcgc tgacttttat gagaaacgaa
      481 caagacattt agagctattt ctaaactaat cggcgaccca tctactgtct ctaaaaaagt
      541 atgtaaacac cttaccatca aggaatcaat caacactcaa aatgtgaggc ccgcccactt
      601 ctaaaacgat taccttatgt gtgtaatggt tgccctaaca agtatataaa ttgtgacttt
      661 actaagcaat tttactacgc catcggagct aaaattactc tgaaaattta cctcaatctt
      721 ttgctaaaaa tcctataaaa gagaagcgaa atacctccta tagataaacc aacgataaca
      781 aaattaaaga tatttttagg gcttaaaaga aaagtaaatg tcattgtccc aatgggcata
      841 aataaaattg caacagtaaa aataatccca aaaactctac caagaaagac attatccaca
      901 ttcttttgga tatatgaaaa aaactgtaag ttgaacatag tcaaaaacaa gttgaataaa
      961 gcaggatata acgcaagcat ataagcactt ggaaaaacac agtataccat aggtgtcaaa
     1021 gatagaaaaa cacctgatac tccaagatat aaaatcattg tttttatttt caaaacttta
     1081 ttgagaatac tgcttaaaga cgctccaata agaccaccta ctgcttctgc tcctaggaaa
     1141 acaccgtata agccaacggt aactcttggg aacatctgat tgctatatgg taacaacaga
     1201 ttataagctg ctaaaaagaa attaacaatc gcagataaaa taaccaagta caaaatttcc
     1261 ttttgactag ctagatacct tcctccttca aaaagatctg aaaagatttt cgataatgaa
     1321 aacacctgtt tcccagtact ttcttcaagt atgggacgaa taaagagaat aagcaaccca
     1381 gatgcaataa atgttatccc atctagacgt aaaataccat ataatcctag taaaccgtat
     1441 agagataccg ataccagggg aacaacgact ttaactaccg ttataaacga ttctagtaat
     1501 gagtttagtt ttgaaatatt atctgcttcc accacttctt tagtaaaagc cttataagca
     1561 gggcctgaaa atgatgagaa aaaagctaat ataatgtttg tgataaccac agcataaatc
     1621 aaccactgct gattagaaat aaaagataag gcaagacaca atactccgct taaaatatct
     1681 gttaaaatga taatccgttt tctttgaaag ttatcagaca gaacaccacc aaaaagatta
     1741 aaaatcacac tgatgatgtt ttctaatgtc tgataaatac caactaacat aagtgactta
     1801 acatttacac tcgataaaaa agtgttattc gcaaagtcaa acataatatc tccaacacga
     1861 gaaataatac ggctccctac aagtaaatat gtattttgtt gttctttttt attcaaaata
     1921 aactcctcag atatttgttc attagcagaa ctcttctaac cattgcttcg caatattata
     1981 gttatcctca tccgaaagag tgtttacttg cttagctata gccatttctc tatcttcaat
     2041 aaacttctta gctgtatata gaatggctgc ctggactaat aaaatataat ttcccaaagc
     2101 ggagtttact acaaaattag ttggtgttcc ttgatttaac agatagaaat agttgtcttc
     2161 actttcatat ctagtgatta atgaagtttc gactatttct tcatattcat ccaataaata
     2221 gctataatta aattcatcat cactagatgt tgcagagact aggaaggttc catctttgat
     2281 agagcgaaaa tctaaaatat ctagactttt tgaaccggtc gcacaaaaaa tcaaatcaat
     2341 attcttgaaa tctttttcta gcaaaatgtc gcaaccatca cgtaccgctt gaatagttct
     2401 catgctatct ttttccagca ccttcggtct aataccaagt tctcttaatt tggtacagat
     2461 gccgtaaccg attttcccat atccaataca aaccacttgc atatattgca ttaataaatt
     2521 tttttgatgt aatatataat ctgtcccaaa aacaatatcc gcaccaacta agtaatcctc
     2581 attcttcttc aggggatttc tagcgacaga aaataacgga tattctattt gatcaataac
     2641 attctcatat ttttgaatcc cattttctgt atcttcaatg atacactcga taggtaagtt
     2701 tggaatctga gcaattgagg caaaataccc accaatgtct aataaaattg ttttactctt
     2761 tatccccaga taatctacat taaaatattc atcccttgaa gctaatgtta atcttacccc
     2821 catattttct agcttgtgcc ataccatctt atcaacagag tttggtttag cacacactaa
     2881 caaacgatgc ccaaatattt tttgcaatgt catgataatc ggtattgtac ttggaataat
     2941 atgttgtaca gtaatacatg atatgtcttc aaacgatgca cctttcagca tattagataa
     3001 aaaacgttct tgagaagctg cttcaagttt ttcaatcttc ttaatgattt ccttatagcc
     3061 gtccatgtcc tttacattat ctagctgaat ccactcatag gaactcgatt cgttgctgtc
     3121 aattttcaca tcaacctcat tttcaatata aaataaatat tgcaagtcat aatggtagtg
     3181 ggaacgctca ttcttcaatt tattttctgg tatcttatgc acagaaacat taaaaggtat
     3241 caagctattc aatggttctg cacattgata cgtcaatatt tcagaatcta tcccagtctc
     3301 ctcaaacagc tcacgtttcg ctgcatctag cgggtttcta tcatttttat caatatgccc
     3361 cccaggctgt aggtatcttt ttaaaatatt atggtgaacc atcaataaac gcctgttatc
     3421 ttttgaaata acaaatgctg atgctgtaaa atgcccaatg aaattctttc tatttatcat
     3481 ctcttgatca tctttttcat taagctgtac caaaacgtta ttcaatttat ccttttcctg
     3541 aatattattc agttggtacc cctctactat atctttataa atactcatcg gtttgtctcc
     3601 tcattttcca gtcgtttttt atcaattact tttagctcga atttgctatc tttatgcatt
     3661 aagtcataaa cactattact caataactca gattttataa ctgcgtatgc aaatcgctca
     3721 tgtacaaata cattaataaa atttttatca aaatcaacat caattatatt attaatagta
     3781 tcttttaacc taaatgcttc gccaatgaaa tttattgata gagacagatt atttaatcgt
     3841 tcttgcactt ctttagcact catatcattt cctaacattg caatttcata gtaatcaata
     3901 cctgtacgat agatctccaa aattttgaaa tgagagtttt taaactcctc aaaagtttca
     3961 gttcgattta cttggaatgg aattttcttg tgaatgtctc ctattaagtc atacgcatca
     4021 aactgttcat aatctctaaa atccaaagat agacccccag atatagcaga cagattatag
     4081 tcgcttaaaa tacactgtga gatagcataa attgtaaaaa gatatacatc gtctccttta
     4141 atatcttctg gtaaagaaac ttgaaaacat tgaacttcat catttaattt ctcaaactca
     4201 atagcaggct ttatctttgg caatctagca agaacatccc cagagacatc attctgtaac
     4261 acctcccttt taaactgcga aaaagcaacc agtgaactac taggtacttc atcaataact
     4321 atcttttttt cgtacagttg atatactgta tctccaagtt tatttaatga tgatgcatca
     4381 atagaatgat atggaaaata aaatcttact tttttatctc ttgttcccac cacaataatt
     4441 ggaataggaa tcacttctat attatctaat attccttgta attctaactc tgttggtaaa
     4501 ttatttagta caataatatt aggtgagtaa tctccttcat tcacaatacc tatgctaaat
     4561 cgagtttgct ccttttcgac aacaagtcta aatatatcaa ttttatagct taaatattta
     4621 ataatatggt gcagcttatt caattctaaa taagtcactt cttccagtgc taaattaaaa
     4681 ccaataacac gattttgatt gtttttataa agtctctttt gtgtcgggct aggagtaata
     4741 atatttttca aataacgata attcattttt gtgagattat actctaaatt aaccaagtca
     4801 tgttctttag taaaactatc gtttggctca gttgaacgtt cttgaaaaaa tgatttattt
     4861 ctaatatagt ccacaatcga atctacactc tttagcctat aaaaatcatt ttctttaatt
     4921 tcaatatcaa agatatcctc aatctctaaa taaaatctaa ctaattctaa cgaatccaaa
     4981 tctgtgatat caactctttc aaatttagat agtacatcta aaatattttt tctaacatca
     5041 tctccttgtt gactttgttt tttataataa tatatctcaa gcatttttgg aacatccaac
     5101 tttctattct gattgagata ataactctca actttaacta ccgtcggatt taagtaacta
     5161 ggtaaacttc taataatatc ttctttaata ttcaaatcgg cttcataaaa tacgacaagt
     5221 ttcttcttat aaaaaacaac tcgtgatgat ttaactgatt taagtttatc tacaatagat
     5281 tttacctcat ctaattcaat acgaatacca tttacttgga cttggctatc tattcttgaa
     5341 ctaaatacca agttatctcc ttggtaataa acgtagtccc ccgttacata gtacctattt
     5401 gaacctatca acttaaactt agctttattt aattcgggtt gtagtctata cccttccgtt
     5461 actccattac caccaattag aagttctgcc atcttagaat tctctttttg agaagctatc
     5521 tttagttgaa ccccaggcaa aggcttacca attggaacag tattatattt tctatctttc
     5581 aactcatagt aggttgcata aattgttgtt tctgaaggcc catataaatt aaatactcga
     5641 cacccttgct gaataagccc tctcaaccta ttcgctaatg aactaggaaa tgtctcacct
     5701 gctagacaca acgctcttaa attctggaat acttctggcc cactaatatc aataatagtt
     5761 tcagcaaaag acggagataa tgataaatga gttatcttct ttttctcaat tgtttctcct
     5821 agtcgaataa tattctgaat cccaccatcg taacaaacca aagtaccacc cgtatataca
     5881 ggtgccaaaa tctctgttaa tgaaacatca aaagtatagg gagttgtaaa taaaaatttt
     5941 gattcggaag taaacttcac aattttataa aattctttta caagccaatc tatgttatca
     6001 tcagttaaaa atactttttt aggaacccca gtagttccag aagtacagat aatatgtgca
     6061 atttcattct ctttagttgt agctacttct tgatactcac tgtaactttc taattttttg
     6121 ggtaagagca aaagagttac tgaatgattt tcaagtttaa catccctatc acttatcaac
     6181 acgtcaaaga caacttcgct aatacgttct aatgatattt tgacctcaag actatttgtt
     6241 ataggtaacg gaattttacc cgatttcatt atccccaaaa caactggtaa aacatactta
     6301 tttttttcta tataaaaagg tacagtctct tcatcgctat tgagtagtag ctgcttagca
     6361 ataaaattag acatcacatc tacttcttga aaagtaaact ctcctccgct atacataaca
     6421 gcaactttag aaggatattg tttcaccgta tcactaaaag tttttaatat ggtcatttct
     6481 cttctcctta atttgattga ttatgcactg tcattcataa tttatccaca cacaacaata
     6541 agaatttcaa aagcaatttt caaagttggc aaaaatttta cctttttcat catttccctc
     6601 ttttatttat catataataa acaaaggctt ttcgtcaccg actacagttg acaaaagaga
     6661 ctttcttatt ttttgcttgg aactttcaaa gcatctttag ttggaatata atctttgttt
     6721 ccaaagaatt tttcagccaa cttagccaaa gtaccatctt tttggagttc ttccaaacgt
     6781 ttgtttacaa atttttgaag atctttttga ttatctgcga a
//
