LOCUS       gnlProkkaOGFBBGLD_46   16569 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|OGFBBGLD_46.
ACCESSION   gnlProkkaOGFBBGLD_46
VERSION     gnlProkkaOGFBBGLD_46
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:10:57
            Original ID  :: gnl|Prokka|OGFBBGLD_46
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16569
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16569
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[3533:11569]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      3534..11569
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..16569
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..16569
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(135..1490)
                     /locus_tag="ctg41_1"
                     /transl_table=11
                     /translation="MKAKDNQADRGDQPLSEKHHMQIPWYDVIVSEERQADHATLEERA
                     SLVGRVGIMLLACGTGAWRVREAMNTVARALRMSCSADIGLISLSYTCFSNNHAYSEVL
                     SLPKSGVNTDKLDALERFVRHFDKEYATQTVRDIHHRLDQIQKMSGNYDPLRAGLAAAL
                     ACCAFVFLLGGGPIEMICCFVGAGIGNWLREIMIRRNWTLLACIGVSVAVACLVYFIAF
                     RGLEMGLGIAARHEAGYIGAMLFVIPGFPFITSMLDISKQDMRSGMERLLYALMITIVA
                     SLVGWLVAMVVHLRPENFVDLGLSPVLLLVYRLIASFCGVFGFSVMFNSPRRMAIQAGL
                     IGAVANTLRLELVDLNTIPPAAAAFIGALVAGLIASAINRVDGYPRISLTVPSIVIMVP
                     GLYIYRAVYNIGLNNIGVGAEWMTRAALIIMFLPLGLFTARLIMDSRWRQSD"
     CDS             complement(1670..2023)
                     /locus_tag="ctg41_2"
                     /transl_table=11
                     /translation="MDYEEELETKGYIDCLLHELHEQPQLIRQTNIEEVVERTKEEIIR
                     DGFHGYELRRHVFRMILRIDFILTTESVRLSQEGRDAIDELRRIANGQKKEDPRRFLRI
                     WRFLAQRFQHHMQ"
     CDS             complement(2142..3521)
                     /locus_tag="ctg41_3"
                     /transl_table=11
                     /translation="MMDPKKLATTEYYQHRFRNFSTMIIMPSTILFLGLLLFLIFARRE
                     VTVLTAAEIEPVKAAVTVQATAANRIVSNRMKEGKRVKKGETLLVYHDVANPTQIKLLK
                     QQLATLKEQQQQLDVLKQSVTENKDLFSKADRFGYQQQVQDYLSQRRVLTLTAEAEQAT
                     QTVASEKNKEIDRLLSASIQTSQAKMAAISEAKAAIQANKPLPNRHAYHYLYQQYESEI
                     KNTDAEAQANLKRQYLAQLQTQLDEEQTNLTSLEQQRAGQKQADVSAQKAGETQANLTA
                     LQSRLQQTAVAEQTKVQQQVQADEAKLATLNDETQSYHVKASASGVLHLETALEGNQYV
                     PSGSVLARILSDLSEQTDADLKLGVSPTEIMSIKRGQKVRLRIAENVPTPTILDGRVYA
                     IDVAPTRDPKVGNFFTVKARVKLSKSQRQALYYGLAGQASVITGTKTYWDYFADKMFNY
                     R"
     CDS             complement(3534..5726)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 310; E-value: 5.3e-94)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_4"
                     /sec_met_domain="Peptidase_C39 (E-value: 1.9e-41, bitscore:
                     133.8, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 0.0, bitscore: 1108.4,
                     seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MVKYTPKLGQITYYKRFYTAQVDERDCGVAALNMLLKYNGSDYSL
                     AHLRELAKTNQDGTTALGIVRAAEALAFETKPVQADMQLFDFEDVPYPFIAHVLKRGEL
                     LHYYVVFKATRTSILIGDPDPSVRMTWLSREVFEKEWSGVAIFIAPAPQYQPRKEDKGS
                     LFAFVPMLAKQKGIIANIILAAVLITVISIVGSYFLQSIIDTYIPNAMRTTMGMIASGL
                     LVAYLLQAVLTYGQNFLMAVLGQRLAIDVILGYVRHLYELPMSFFSTRRTGEIVSRFAD
                     ANKIIDALANTIMTLFLDVWIVLILGIVLGIQNGTLFLVSLIAVPCYLVIVFAFQRPFD
                     RLNQETMESNAILSSSIIEDLNGIETIKSLTGERVSYERVDREFLTYLKKSFSYTKADQ
                     LQQAIKGLLKLALNVVVLWIGASLVIANRMSLGQMLTFNALLSYFTNPLESIINLQPKL
                     QMARVANNRLNEVYLVESEFKEQRHLTERHLIEGPLRVRDVSFKYGFGQGVLKNVNLEV
                     PENAKYTIVGMSGSGKSTLAKLLVGFYPVDADKGTITFNGIPVKDINLTTLRQYIEYVP
                     QDPFIFSGTVLENLTLGSRSDVSEQDLTQACLVAEIAADIANLPQQWQTKLSESGSILS
                     GGQKQRLAIARALLSPAKVLIFDESTSSLDTITERKIVDRLLAMTDRTIIFVAHRLTIA
                     AKTEQIVVMDHGKIVEQGDHATLLAQDGYYARLVHE"
     CDS             6356..7651
                     /locus_tag="ctg41_5"
                     /transl_table=11
                     /translation="MTVASNITYFFITFPIFATGIYFLTVIFDSRFRVIHITFWSIFGT
                     LLSLLLSTYGEVIFFIIYTCYIVKTTSRSNIFWIFIFMEANLVVITIQSSITQALISAK
                     AHLEPWTLISDSVINLAIIIAIFWLLSNKKEQILKLRDLVQEQNKLQHSVLIYTGATCA
                     SLYCFEATWELIDLNNFLSWLSLGVFLLSVVISLYSIFFILKSYKYYIELIWIKRAESS
                     QRAYYATLAQQQKRTDKLLHDYKNLLATLQLSMDQSTHDISSETRDVVSKAQQALSQVE
                     VNQETFDAIKSDSLKSLLYLKWTEALHQNIKMYVHIEGIIEPLDSSTSFAVIRALGILI
                     DNALEETSRSGNSKFSVLLINSSSYLEVNVINDVTAGFELSNLNQPGFTTKGHGRGKGL
                     TIINELIEQNKKISLKKKVKDNQLKITLFVWR"
     CDS             7656..8432
                     /locus_tag="ctg41_6"
                     /transl_table=11
                     /translation="MSKNKTILNIYILEDNPDYLTFIQETVQQYLLIEELPAKIRLATT
                     SATELLATIDWSAINDSIFLLDIELGDSATSGVDVATAIRKKSYYVDILFITSHVDEAL
                     RILEHKIAPLDMINKNSPSKTEKKIRNNILYAIKRLKARQVASPRLFSYSINSSIFSLD
                     MDELIYIQTAPGVSGTLELHAENEITTFPGNLKELATKYTNLCRCHKSILINPAHVLRL
                     DITNRFVYMDNQDKLEVSIRRMGELRNILTGTRALS"
     CDS             complement(8551..8811)
                     /locus_tag="ctg41_7"
                     /transl_table=11
                     /translation="MNLYYATWLIFLATLFVFKDRKFVKRMISAILDDGNLGFGIRIVI
                     WLALLGLFFVTNHTDWPSAVLILLIVSAVILIDWHKTFQEE"
     CDS             complement(10281..10580)
                     /locus_tag="ctg41_8"
                     /transl_table=11
                     /translation="MNKLKWFAGGNERAEQAIQLIDELLRDFDDSSSHSDRLRTVLRNN
                     REALIHKQAAVPFILSRMNLEISNALLQNNILLTKQQSDKFEQLSSLANIRYGY"
     CDS             complement(10758..10916)
                     /locus_tag="ctg41_9"
                     /transl_table=11
                     /translation="MTKLNEAELSKISGGIGPLVIPVAAILGFLATDAWSHADELVAGV
                     KQGWERS"
     CDS             complement(11384..11569)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg41_10"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 1.6e-08,
                     bitscore: 27.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDHLKTLNTADLASISGGDNGNLWTFIGKAIGSTARSWAEGAMFA
                     PAIGPAKEMVDKFKGN"
     CDS             complement(11629..11814)
                     /locus_tag="ctg41_11"
                     /transl_table=11
                     /translation="MTTRTRLALKEISEEKLEMTTGGNVPLSNCSVDPPNERHPPAYEA
                     AFKYKLPIVHPIKVAT"
     CDS             complement(12206..12391)
                     /locus_tag="ctg41_12"
                     /transl_table=11
                     /translation="MPTRLTKLVDYGLIIATIIFAIYTVTSAIGWTNHGSFVTPMLILM
                     TLLMLLSEREEKQKKA"
     CDS             complement(12441..13247)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Abi"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg41_13"
                     /sec_met_domain="Abi (E-value: 2e-14, bitscore: 46.6,
                     seeds: 823, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MERKRHLLLSPGFCVLYILLLVVLISQLLLIPAVYTLKLDFWAGN
                     ILFKAIILLVMIALNWLLLKQAIVLKVTLRRPRLKPVVIWGLLLMLIGWFTVTNRTPID
                     VLQAAVIGTIAAVPEEYLFRGVMLGGLIRAFYVAHHRHAKYQLLFCVGLSSLVFSLAHL
                     SNLPAQGLVITIAQVIQAFGMGAIFAALYIRYGSLLMPILIHFLIDFVITLVSGPYPKE
                     APSDPNAITMTIVHAFLIAGIYLAIALRLFRRGQNNEEFLARLSHS"
     CDS             complement(13568..14008)
                     /locus_tag="ctg41_14"
                     /transl_table=11
                     /translation="MAFSVAFSQALEITAYVNSKSQAQHEDYLSIQKISEMLNIPVPSI
                     KKISSTLKKSGILTSKTGLNGGLRLAKTPQTITVYEILTAIEGTAPLFKLHQGIDPAAF
                     VNGERVTSWLAASTNVLNQAEDAMVQVLKQTSIADLAEAAEA"
     CDS             complement(14063..15490)
                     /gene_functions="transport (smcogs) SMCOG1005:Drug
                     resistance transporter, EmrB/QacA (Score: 326.4; E-value:
                     3.7e-99)"
                     /gene_kind="transport"
                     /locus_tag="ctg41_15"
                     /transl_table=11
                     /translation="MSKEEDKELINDGLADDTVIEETDAAITQSQRMSATQVIILGLAL
                     IGAFLGVLDTSIVYTGTVKMAVQLHLNAGALSWVQVAYALTYAGLMLVGGKLGDIYGRK
                     PLFIASLAIFGVGSLAVGAATNALVMISFRAVQGVGAAILAPNCLALLTDTFQGKARQR
                     AIGYYASVIGAGAAVGLVIGGFFATFASWRVGFYMNGPIALIMVGIAVRYLPSAKRQTG
                     KIDWIGTILSVLAMTSISYGLDGSPWPILTLLISAVLWVAFIASQGRVAHPTMPLEIFT
                     DRERMASYVSSLLFSAAAIGFWFYTPQFMQGVLGLTPFMTALGMVPMAILLFIVAVKAR
                     TFVDRWRNSRVMIFGFVTVLLSLAELAVASRFANYWFLLLGTLGFAVGFALAFATLATS
                     GLARIRPEISGAASGVYNTARQFGGALGLAIFAASTASLSKIADVFGQAMLIGVGMTIV
                     GLILVVALIIPAEKAAK"
     CDS             complement(15663..15995)
                     /locus_tag="ctg41_16"
                     /transl_table=11
                     /translation="MNMVQRNQILFILTGLNLSLKQAASGGLMETEAQEVVDEALDILK
                     RPNVLKNRAADYALSRLYARFTRLIGLQGMKLSAEANQWWQAVKDFMENDIHGELSQVG
                     GPHFII"
ORIGIN
        1 gtacaacctt tgccttgaac tcacttgaat atttagtcat aaaaatgccc cacaatcgtt
       61 agagtatctg tctaacaatt atggggcact tcatttgaag tggggttatt tgtgttgcta
      121 aaaagttata ctgatcaatc gctttgccgc cagcgagaat ccataatcaa gcgagcggta
      181 aacaagccca gcggtaaaaa cataatgata agtgcggcac gcgtcatcca ttcggcaccg
      241 acgccaatat tattcaatcc aatattgtaa actgcccggt aaatatacaa gccaggcacc
      301 atgatgacga tggatggcac tgttagcgaa atccgcggat agccatcgac gcgattaatc
      361 gccgacgcaa tcagtccggc taccaacgcg ccgataaatg ccgccgcagc agggggaatc
      421 gtgttgagat ccaccaattc aagccgcaac gtattcgcca ctgccccaat caacccggcc
      481 tggattgcca ttcggcgggg gctgttaaac atcaccgaga atccgaagac cccacaaaag
      541 ctggcaatga ggcgataaac caaaagaagg accggactca aacctaagtc gacaaagttt
      601 tccgggcgta aatggacaac catcgcgacc agccagccaa ccagcgaagc cacaatggta
      661 atcatcaacg catacagtag tcgttccatt cccgagcgca tatcctgctt cgaaatgtcc
      721 agcatactgg tgataaacgg gaaacccgga atcacaaaca acatggcgcc gatatacccc
      781 gcttcatgcc gcgctgcaat acccagtccc atttccagtc cgcgaaaagc aataaaataa
      841 accaaacagg caaccgccac actgacaccg atacaagcca gcagtgtcca gttacgccga
      901 atcatgattt cacgcagcca attaccgatc cctgcaccaa caaaacaaca gatcatttcg
      961 ataggaccgc cgcctagcaa aaagacgaaa gcgcaacacg ccaaggctgc tgccaatccg
     1021 gcgcgcaacg gatcgtaatt gccagacatt ttttgaattt gatcaagtcg atggtgaata
     1081 tcccggacgg tttgagtcgc atactctttg tcaaaatgac gcacaaaacg ttccaacgca
     1141 tccaacttgt cagtattcac accgcttttt ggcagtgaaa gcacctcaga ataggcatgg
     1201 ttattgctaa agcaggtata cgataaggaa attaggccaa tatctgctga gcacgacatc
     1261 cgcaatgctc gagcaacggt gttcatcgcc tcacgcacgc gccacgcccc ggtaccacac
     1321 gccagcaaca tgatcccgac tcggccgaca agtgacgcgc gctcttcaag ggtggcatga
     1381 tcggcttgtc gctcttcgct gacaatcacg tcataccacg ggatctgcat atgatgtttt
     1441 tctgaaagcg gttggtctcc ccgatccgct tggttatctt ttgccttcat aactcgtgct
     1501 aatccttctt cttataggga ttgtcttttt caaaaaaatt gaaaataaac attcactatt
     1561 ctagcacaat tcataacagg gtgtattttt gactttttga aactaacgga tttgaccgcc
     1621 ttattcatga caagcatgca caaattagca atcatttctc ggtctcaact tattgcatat
     1681 gatgttggaa tcgctgcgcc agaaaacgcc agattcgcaa aaagcgacgg ggatcttcct
     1741 tcttctgtcc attggctatc cgtcgtagtt cgtcaattgc atcgcgacct tcttgactca
     1801 accgtacact ttcagtcgtg aggataaaat caattcttag tatcatccga aaaacatgtc
     1861 gtcgtaattc atagccatgg aaaccatcgc ggataatctc ttccttggtt ctttccacaa
     1921 cttcttcaat attcgtttgg cggatgagct gcggttgttc atgtaattca tgcaacaggc
     1981 agtcgatata gccttttgtt tctaattctt cctcgtaatc catacgccga tcaccgcctt
     2041 tcatttgact aacttgatcc gcatcgtttt tttatggtca ttttcttaaa taatgggcat
     2101 cgcattttcg ctactaaacg acaaaagcgg taaataccga ttcatcgata gttaaacatc
     2161 ttatctgcaa agtaatccca ataagtcttt gtgccggtga taacagatgc ttgaccggct
     2221 aatccataat aaagggcctg ccgctgcgat ttagataatt tcacccgcgc cttgaccgta
     2281 aagaagttgc caactttcgg atcgcgtgtc ggggcgacgt caatcgcata aacccggcca
     2341 tctaatatgg taggggtcgg cacattctca gcaattcgca ggcgtacttt ctgcccacgc
     2401 ttgatgctca tgatttctgt cggcgaaaca cccaatttta agtcggcatc cgtttgttcc
     2461 gataagtccg acagaattcg tgccaacacg cttcctgaag ggacgtattg attcccttcc
     2521 aaggcagttt ctaaatgcaa aacgccactg gcacttgctt tgacatgata gctttgagtt
     2581 tcatcattca aggtagctaa cttagcctcg tctgcttgga cctgttgttg aaccttcgtc
     2641 tgttccgcaa cggctgtttg ctgcaaccga ctttgtaatg cggttagatt agcctgagtc
     2701 tcccccgctt tttgagccga tacatctgct tgtttttgac cggcccgttg ctgctctaaa
     2761 gacgtcaaat tggtttgttc ctcatccaac tgtgtctgta attgagcaag gtactggcgt
     2821 ttaaggttcg cctgtgcctc cgcgtcggta ttttttatct cactttcata ttgttgataa
     2881 aggtagtgat aggcgtggcg attgggcaag ggtttgttcg cctgaatcgc cgcttttgcc
     2941 tcggagatag cggccatttt tgcttggctc gtttggatac tggcgcttag taaccgatca
     3001 atctctttgt ttttttcact agcgacggtt tgggttgcct gctcagcctc tgctgtcagt
     3061 gtcagcactc ggcgttgact cagataatct tgcacctgtt gttgatagcc gaatcggtct
     3121 gcctttgaaa aaagatcttt gttttcggta acactttgtt tcaaaacatc caattgctgc
     3181 tgttgctctt ttagcgttgc cagttgctgc ttgagtaatt taatttgtgt tggattggcg
     3241 acatcgtggt aaacaagtaa ggtctcgcct ttcttcacgc gcttgccttc tttcatgcgg
     3301 ttcgagacga tccgattggc ggccgtcgcc tgaaccgtca cggctgcctt taccggttca
     3361 atttcggcag ctgtcagcac agttacctcg cgccgagcaa agatcagaaa caatagcaag
     3421 cctaagaaaa gaatcgtact aggcataata atcattgttg aaaaattgcg aaagcggtgc
     3481 tggtaatatt cggtcgttgc aagttttttg ggatccatca tctaaagctc acctcactca
     3541 tgaaccaggc gcgcgtaata accgtcttgg gctaacaacg tcgcatggtc accttgttcc
     3601 acaattttgc catgatccat caccacaatt tgttcggttt tagccgcaat ggttaagcga
     3661 tgggcaacaa aaataatggt ccgatccgtc attgccagca agcgatcgac aatttttcgc
     3721 tctgtaatgg tatccagact gctggtcgat tcgtcaaaaa tgagtacttt tgccggtgat
     3781 aacaaggctc gtgcaatcgc cagccgctgc ttctgacccc ctgataaaat gctgccgctt
     3841 tctgacagtt tggtctgcca ctgctgcggt aagtttgcga tgtctgcagc aatttccgca
     3901 accaaacacg cctgcgtcaa gtcttgttcc gaaacatccg aacggctacc taacgtcaaa
     3961 ttctccaaca ccgtccccga aaaaataaat ggatcctgag gtacatattc aatatattgc
     4021 cgtaatgttg tgagattaat atctttgacc ggaataccat taaacgtgat ggttccttta
     4081 tcggcatcaa ccgggtaaaa gccaactaat aattttgcta atgtcgactt accagaaccg
     4141 ctcatgccga cgatggtata tttagcattt tccgggactt caaggttgac gtttttcaac
     4201 acaccttggc caaaaccata tttaaacgaa acatcccgaa cgcgtaacgg gccttcgatt
     4261 aaatgccgct ccgtcaagtg ccgctgttct ttgaattccg attcaaccag ataaacctca
     4321 ttcaaacgat tgttagcaac ccgcgccatt tgtaactttg gctgtaggtt gatgatgctt
     4381 tcaagcggat tcgtaaagta tgacagcagc gcattaaagg tcagcatctg ccccaaactc
     4441 atccgattgg caatcaccaa acttgcccca atccacaaca ccacaacgtt caacgccagc
     4501 ttcaacagac ctttaatcgc ttgctgtaat tgatctgcct tagtgtaact aaacgatttc
     4561 ttcagataag ttagaaattc ccgatcaacc cgttcatagc taactcgttc gccggtcagg
     4621 gacttgatgg tttcaatgcc attcaaatct tcaataatcg atgaactcaa gattgcgtta
     4681 ctttccatcg tctcttggtt caaccgatca aacggccgct gaaatgcaaa aacaatcacc
     4741 aaataacacg gcacggcaat caatgacact aaaaacaaag tcccattttg gatccctaga
     4801 acaatgccta atattaggac aatccagaca tccaaaaata acgtcataat cgtattcgcc
     4861 agcgcatcaa taattttatt cgcgtccgca aaccgcgaca caatctctcc ggtccgccga
     4921 gttgaaaaaa acgacatcgg caattcatat aaatggcgca cataccctaa aatgacatca
     4981 atcgcaagtc gctgccccaa caccgccatc aaaaaattct ggccataagt caacacagct
     5041 tgcagcaagt aagccaccaa aaggccacta gcaatcatcc ccatcgtcgt ccgcatggca
     5101 ttcggtatat acgtatcaat aatagactgc aaaaaatacg acccaacgat actaatgacc
     5161 gtaatcaata ccgcggccag aataatgttc gcgatgatgc ctttctgctt agctagcatg
     5221 ggtacaaacg caaacaaact gcctttgtcc tccttacgcg gctgatactg cggcgccggt
     5281 gcaataaaga tggccacacc cgaccattct ttttcaaaca cctctcgcga aagccaggtc
     5341 atgcgcactg acgggtcagg atcgccaatc agaatactcg tgcgcgttgc cttaaaaaca
     5401 acataataat gaagcaattc accacgcttc agcacatggg caataaacgg ataaggcaca
     5461 tcctcaaaat caaacaactg catatccgcc tgcaccggtt tcgtctcaaa cgctagtgct
     5521 tcagcggccc gaacaattcc caaagcagtc gtgccatcct gatttgtctt cgctaactcg
     5581 cgcaagtggg ctaacgaata gtccgaccca ttgtatttaa gcagcatgtt taacgcagcc
     5641 acaccacagt cacgctcgtc aacttgtgcg gtgtagaagc gtttgtagta ggtgatctgg
     5701 cctagttttg gggtgtattt aaccattaac tctcctcgct tattaagcca ttagattcag
     5761 gcctctttta tgaacttata tgtcaaaaca gttagccaaa gatacaggtg aagtatcgca
     5821 aacttttgct taacagcttt gatctaagtg tcgtaagatt tagttttttg catttaaaat
     5881 atgtggtagt atattttaaa gcagataaaa tagcatataa aaataaatat tcattttaaa
     5941 agtactttta tatttaaata tttattctta tatgcttaaa gcaattatgt gctcagcttt
     6001 ttcaaaagac gtatatggct ttaatgcttt ctttgaaact gttctatcag ccattttttt
     6061 atattttcaa acgcttggct tgttggtcgc aaattgccac catgtatttg tacgagccgc
     6121 tcatccgaaa tcacgctgtt tttcatctga ctctgaaacc cctttttgtt gttcacttca
     6181 aactacctcc tatgatttat tcttctgttt ttaacctaac atgtcgtgag ctttttgggg
     6241 catacaaaaa ataaacgtcg tgttttggcc atttaacgtc attgtgtcag cagatgacgt
     6301 catttatctt cattcaaaac ttgccatact ttcataactt gcggaggttt tctatatgac
     6361 agtggcgtca aacataacct acttctttat aacttttcct atttttgcga ctggaattta
     6421 ctttcttacc gtcattttcg acagccgttt cagagttatc cacatcactt tttggtcaat
     6481 cttcggaacc cttctgtctt tgctcctttc aacttatggc gaggtcatat tctttataat
     6541 ctatacgtgc tatatagtta agaccacttc acgttctaat attttctgga tttttatctt
     6601 tatggaagcc aaccttgttg ttatcacaat tcaatcctct attacacaag ccttgatctc
     6661 agctaaagca caccttgagc cttggacatt aatttccgac tcagttatta acttggcaat
     6721 aatcatcgcg attttctggt tactttctaa caagaaagag caaattttaa aactgcgcga
     6781 cctagttcag gaacagaata aactgcaaca ttcagttctg atctacacag gcgcaacctg
     6841 tgcgtcacta tactgttttg aggctacttg ggagctaatc gatctcaaca acttcttatc
     6901 ttggttaagt cttggcgtat tcctactttc agttgtgatc agcctttatt caattttctt
     6961 tatcttaaaa tcctataaat attatataga gctcatctgg attaaacggg cagaaagttc
     7021 ccagcgtgct tactatgcaa cgttagcaca gcaacaaaag agaacggaca agctccttca
     7081 tgattacaaa aacttattag ccacgttgca gttgtcaatg gatcaatcaa ctcacgacat
     7141 ttcttctgag acgcgagacg ttgtttcaaa ggcacaacaa gcgctatctc aagtcgaggt
     7201 caatcaagaa accttcgatg caattaaaag cgattcgctg aaaagtctac tctatttaaa
     7261 atggacagaa gcgctacatc agaatatcaa gatgtacgtt cacatcgaag ggatcattga
     7321 accgctcgat agcagcactt cattcgcggt cattcgcgca ctcggtattt taattgacaa
     7381 cgctttagaa gaaacaagcc gctccggaaa ctcaaagttt agtgtcttat taatcaattc
     7441 aagctcgtac ctggaagtta atgtcatcaa tgacgtgacc gcgggatttg aactatcaaa
     7501 tcttaaccag cctggattta ccaccaaagg ccatggtcgc ggaaaggggt tgaccattat
     7561 taacgagctg attgaacaaa acaaaaaaat cagccttaag aaaaaggtca aagataacca
     7621 gttgaaaatc acactttttg tatggaggta actttatgtc taaaaacaaa acgatcctaa
     7681 acatttatat tctcgaagac aaccctgact atctaacctt tatccaagaa actgtgcagc
     7741 agtaccttct gattgaagaa ctacccgcca agatccggct ggcaacaacg tcagcaaccg
     7801 aactgctcgc aactattgat tggtcagcca tcaacgatag tatcttcctc cttgatatcg
     7861 agctgggaga ttcagcgaca agcggcgtag atgtagccac agccattcgg aaaaagtcat
     7921 attatgtcga tatcctcttc atcactagcc atgtagatga agctttaagg attttagagc
     7981 acaaaatcgc accgttggac atgatcaata agaactcacc ttcgaagaca gaaaagaaaa
     8041 ttcgaaataa cattctttat gcaataaaac ggctaaaggc gcgtcaggtc gcatctccca
     8101 gattgtttag ctacagcatc aactccagca ttttttcact tgatatggat gagctcatct
     8161 atattcaaac tgctcccggt gtctcaggga cactggagct tcatgcagaa aatgaaatca
     8221 caacctttcc cggcaacctt aaggaactag cgaccaaata taccaactta tgtcgatgcc
     8281 ataagagtat cctgattaat cccgcacatg ttttgcgtct ggacatcaca aaccgattcg
     8341 tttatatgga caatcaagat aaacttgagg tcagtattcg gagaatgggc gagttgcgca
     8401 acatcttaac aggcacacgg gctttatctt aagaagagtg tgactgggca atcatcctag
     8461 atttctgtta atcaacacag ctgaacgcac aaataacgca tcctcaatat caagggtgcg
     8521 ttatttggtg gtttatacag gttggaaata ctattcctcc tgaaaggttt tatgccaatc
     8581 aattaaaatt actgcactaa cgatgagcag tataaggact gccgaaggcc aatcagtgtg
     8641 atttgtgaca aagaaaagcc ctaaaagagc caaccatatg acaattctga taccaaatcc
     8701 taaatttcca tcatctaaaa ttgcggaaat cattcttttg acaaatttgc gatctttgaa
     8761 aacaaacaaa gttgccaaaa agataagcca tgttgcgtaa taaagattca cagtgctact
     8821 ccttcatcag ctctacttca accaacgcgc tatcgactga cccgtttgat aaccagcgtc
     8881 ataaatcccc tttaaaattc ccggtgaaaa gtaccaaaac gacattatta aaaccccaat
     8941 ggcgacaagc aacgacactt tctgttggaa tgataatctt gcaaattgat cgattacgct
     9001 cacctcgttt acaaacagac ttatttttac ttctttcagc aatccattag taacctgttc
     9061 tttatgttct cccaccttct aagaaaaagg caatatacta atggccaact gcatcaattg
     9121 ggaacatttc tcccaaaaag atgttcgcgc atgaagccga tgtcttaaga ggtctatcat
     9181 ctgccagctg atcgcagtta caaatacgaa tgtgaagaaa aatgccagaa tcaaaagcat
     9241 agaatataac acaactgtca taagcaaagc tccttgagtc ttcctttaaa cttacattga
     9301 ggcggcaaat tagcgagcac aggttcggag atactatacg ttctgctagg gtcggtcata
     9361 caagcaagga gtcacaaaaa atgacaccat tttagctatt taatgctgtt tcctaaagcc
     9421 cttttgctgt cagggaaaaa acaattgttg gttttgaaag ctcatcttgt ttagcatctg
     9481 ttctgccata ctcacgcgca agatctcctg atttgtattt ttgtttcaat acaaatcagg
     9541 agaccttttg cggtttttgg ctgatagaac atagggtaac aagattctga cactaaaagc
     9601 agtttccaaa tatcagtagt gtcacctaaa atctcatttg ccgtcatgaa cagtcgacat
     9661 tgcattatta tggcctggca gatagctgtg tcacaatagt tgctgtctct cggtgctgac
     9721 aggcttccta ctgacaatga cgctgccgcc ttaccaatac ttcgaaatca aacaaagaaa
     9781 atttgttatt tagagcgttt atgatcttta acccttgaag atgcgacact tattttagaa
     9841 aaaagaatca aaacaatgaa gattgaaagc atctcaatga acgcccggac gatgaaaaaa
     9901 tcaaaaccca agcaatcgac aatcagcttg tttaagctat cactgagcga gaacccgccg
     9961 aaaaagatac aaacgataat ccagaaagaa gcttcattaa gccatgtgtg catagtttta
    10021 agaatcgtca tcgtacctcc gctttgctca tcactaaatc atttatcgac cgatcagttt
    10081 tggctctgtc tttttaagtt agaccgttat attcgaaact agtttgccaa agtcgccgtt
    10141 ataaattgga caacctttta ggcatcatcc attgacaaca agcccatacc aaccagcatc
    10201 gcaatcggag tttgatctgc accaaatgaa tcagtgaacc taaccataat caagcgcgct
    10261 caccgtttta gtagtggctt ctagtaccca tatctgatat tcgccagcga agaaagctgc
    10321 tcgaatttat cagattgttg cttggttaac aaaatattgt tttgcaacag ggcattagag
    10381 atttctagat tcatgcggct taaaataaat ggaaccgctg cttgcttgtg aattaaggcc
    10441 tctctattgt tccttagcac tgtccgtaag cgatcactat gggaagaact gtcatcgaag
    10501 tcgcgaagca gctcatcgat aagctgtatc gcttgttcag ctcgttcatt cccgccagca
    10561 aaccatttca atttgttcat cattcactcc aaaaaacgtt gtgcttgtgc atcttcactt
    10621 gtaacacgtt tggcgccgtg cattgccaga tctgccgtag caataacggt aagtgcgtgc
    10681 tcgcccacag ataaaaactt gttctgggga gagatacttt tacaacggcg aaatcgctaa
    10741 aaatcaacgc accgttatta cgatcgttcc catccttgct tgaccccagc taccagctca
    10801 tcagcatggc tccacgcatc tgttgccaga aatccaagaa tggcagcgac agggattacg
    10861 agcggtccga taccgccgga aatcttactc aattcagctt cattcaactt agtcattaaa
    10921 attaccccct tgtatttgta gaaactactc gccagttgat ccaaaagtcc ttgttatgga
    10981 tatcgtggcg ataaaacact catcaaccgc acaacttttt gcaaatacaa ccattgagtc
    11041 atcatcggca tgcctggatt aaggccactt gaccttcacc atcgaaattc gactactgga
    11101 tttgtatggc agcattacag cgtacggctt aggcattgaa cggaacactc aaagtttaag
    11161 cgtaggtaat aaaccagatg gcattcaaaa tataagcacg tttaaaggct atctgatgcc
    11221 cactgtcgag atatttatca ttcccaacgc gatagtgacc atctttttta cagcacgtat
    11281 ataccaaaac acctaataga tataccaaga taaacgtagc taacattaaa agatttatct
    11341 tattcatacg ttcgcccgtt cgagtgccta ttcatcgcgg atgctaattg cctttgaact
    11401 tgtcaaccat ctctttggca ggaccaatgg ctggtgcaaa catggcgcct tcagcccaag
    11461 aacgcgcggt tgaaccaata gccttcccga taaaggtcca cagattacca ttatcgccac
    11521 cagaaatgct tgctaagtca gctgtgttta aagtttttaa atgatccatg tttttcctcc
    11581 ttttttcttt atgagcctgt caatgtatta atcagcccag gttattgctt aagtcgccac
    11641 cttaattgga tgaacaatcg gcagtttata cttaaatgcc gcttcgtaag ctggcggatg
    11701 gcgttcgttt ggtggatcca cactgcaatt ggataaagga acattcccac cggtcgtcat
    11761 ttcaagcttt tcttctgaga tttctttcaa agctagccgc gttcgtgtgg tcatcccatt
    11821 tttctccttt ccctttgtta gaaggacttc ccttcttcct catcaatata aagtagacag
    11881 ccaggtttgt gggaatgaat tttttaacgt cgatttttgc aagaaaatcg tcgtaaaaaa
    11941 cctaattttg acgtttatcg ttaaaaaccc ggcgattatt tgatattgcc gccttctctt
    12001 caaaactcaa gcaactgcaa ctgtaactgt atttactttt acccatgtct ttttcgccac
    12061 tgtgagcatc cagtcttaag ccaacttaga aaggcgatca ggctcgcggc cagcatgtgc
    12121 atccattcac cgggaaagtg ataacaaact gcacacatat aaccgacaaa aaatgttaat
    12181 aaacagcgcc aaaatctttt ttgattcacg ctttcttctg cttttcctcc cgctcactca
    12241 acagcatcaa caacgtcatc aaaatcaaca ttggcgtcac aaaactgccg tgattggtcc
    12301 acccaattgc cgatgtgacc gtataaatgg cgaaaataat ggtagcgatt atcaacccat
    12361 aatcgactag tttagtcagt cgcgtaggca tcgtttttct ccttaaactc gttctatcat
    12421 aattgataca gacagccgcg ctacgaatgc gataaccgtg ccagaaactc ttcattgttt
    12481 tggccacggc gaaaaagtcg cagtgcaatc gctaggtaaa tcccggcaat aaggaatgcg
    12541 tgaacaatcg tcatcgttat agcgttggga tcactaggcg cttctttcgg atacggtcca
    12601 ctaaccaaag tgataacaaa atcaatcaaa aaatggatca atattggcat aagcaacgat
    12661 ccgtagcgaa tataaagtgc tgcaaaaata gcccccatgc caaatgcctg gatcacttgg
    12721 gcaattgtta tcacaagccc ttgagcaggc aaattactca ggtgagccaa tgaaaaaacc
    12781 aagctgctta accctacgca aaataagagt tggtatttgg catggcgatg atgggcaaca
    12841 taaaacgccc gaatcaaacc gccaagcatg acgccacgaa acaaatactc ttctggaaca
    12901 gcggcaatgg taccaatcac agctgcttgc aagacgtcaa tcggtgttcg atttgtaacc
    12961 gtgaaccacc cgataagcat caagagcagt ccccagatga caaccggctt caatcgtggc
    13021 cgcctaagtg tcactttcaa gacgatagct tgtttcagca gcagccagtt aagtgcgatc
    13081 atcaccagta aaatgatggc tttaaataag atattcccag cccagaagtc caatttcagc
    13141 gtgtaaactg ctggaattaa aagcagctgg ctgattagca caaccaaaag caagatatat
    13201 aaaacgcaaa atcctggcga caatagcaaa tgacgttttc tttccattta ttcaccttca
    13261 ctcgcacgtt tcaatgcaaa gcagcttcga tatcgctacc cacaatatac cgagtcttcg
    13321 catgttacgg atcattaact tttaaacgtc gggttttcac cgataatcgt tgtgttttga
    13381 aacttgacaa cgcgttaatc gtccccattt ccgaaaaggt cggcaaatgg aggcgcactt
    13441 gctgactatt tactgactgc cccacagttg cacgatcctg aaaatgccgt aagcaaaatc
    13501 gcctcatcca atgccaacgc gccaacgtca gtcttggatg aggcgatgaa aagttagagt
    13561 tcgatattta cgcttctgcg gcttcagcca aatcagcaat gctcgtctgc tttagcactt
    13621 gcaccatagc atcttcggct tggtttaaaa cattggtgct tgccgctaac cagctcgtga
    13681 cgcgctcgcc gttgacaaac gcagctggat cgattccctg atgaagctta aataacggtg
    13741 ccgtcccttc aatagccgtt aagatttcgt aaactgtaat cgtttgtggc gttttggcta
    13801 atcgcaaacc gccattgaga ccggttttcg acgttaaaat accacttttt ttaagtgtag
    13861 acgaaatttt tttaatgcta ggaaccggaa tgtttagcat ttcggaaatc ttttgaattg
    13921 ataaatagtc ttcgtgttgt gcttgggact ttgagttgac ataagccgta atttcaagtg
    13981 cttgcgagaa tgcgactgaa aaagccatcg aatatacctc ccattaggcg attgtgtata
    14041 ttctattata ccaatgatac cgttacttgg cggctttttc tgccggaata atgagcgcga
    14101 cgacaagtat taagccaaca atggtcatgc caacgccaat caacattgcc tgtccgaata
    14161 catcggcaat tttagataag ctggcggtcg aggccgcaaa aattgccagt cctaaagcgc
    14221 cgccaaattg tcgggcggtg ttgtagacgc ctgatgcagc tcccgaaatt tccggccgaa
    14281 ttctagccaa acctgaagta gcgagtgtgg caaatgccag cgcgaatcct accgcaaatc
    14341 cgagtgttcc gagtaacaaa aaccagtaat tggcaaaccg tgatgccact gccagttcag
    14401 ccaatgaaag tagcaccgtg acaaatccga agatcatgac ccttgagtta cgccaccgat
    14461 caacgaaggt ccgggccttg actgccacaa tgaacagtag gatggccatt ggcaccatac
    14521 ctaacgcagt cataaatggc gttaatccta agacgccttg cataaactga ggtgtgtaga
    14581 accaaaagcc gattgcagcg gcactaaaca acagagaact gacataagaa gccatccgtt
    14641 ccctatccgt aaagatttcc agtggcattg tcgggtgggc aacgcgacct tgactagcaa
    14701 tgaatgcaac ccaaagaact gctgaaatca gcaacgtgag gattggccat ggactgccat
    14761 ctaacccata tgagattgaa gtcatcgcta atactgacaa gatcgtacca atccagtcaa
    14821 tctttccggt ttggcgtttt gcactaggta aatatcttac cgcaatacca accatgatta
    14881 acgcgatcgg accattcatg tagaaaccga cccgccatga cgcaaatgtt gcaaagaagc
    14941 cgccaatgac taaaccaacc gctgcaccgg ctccaatcac agaggcgtag tagccaatcg
    15001 cccgctgccg tgcttttcct tgaaaggtgt cggttaacaa tgctaaacag ttcggtgcaa
    15061 gaatggccgc gcccacgcct tgcacagcgc gaaagctaat catgacaagc gcattagtag
    15121 ctgccccgac tgccagactg ccaaccccga aaatagctaa actcgcaatg aataatggct
    15181 tgcgtccgta tatatcgcct aatttaccgc ctactagcat cagcccagca taagttagcg
    15241 cataggccac ctgcacccaa gacaacgcgc cagcattcaa atgcaattgt accgccattt
    15301 tgacggtacc tgtgtaaaca atcgatgtgt caagcacacc tagaaaagcc ccaatcagtg
    15361 ccagacctaa aataatgact tgagtcgctg acatgcgctg cgattgggtg attgccgcat
    15421 ctgtttcctc aatgacggtg tcgtcagcca ggccatcatt gattaattcc ttgtcttctt
    15481 ctttgctcat atgagatgcc cctttctatg gtttacttag tatattccgt ttatactaat
    15541 atggcaaatc ttttttgagc aaaaaaacca cgtgttcctt aattctgtgg aaacacgcgg
    15601 ctacaagcga attcttttcg ggccggttac tggaatcaga ccatggcttg ggcaacaact
    15661 gtctaaataa taaagtgcgg cccgcctacc tgactcaatt cgccatgaat gtcattttcc
    15721 ataaagtctt ttaccgcctg ccaccactga ttggcctctg ctgaaagttt cattccttgc
    15781 aagccgatta atcgcgtaaa ccgtgcgtat agtcgcgaca aggcgtaatc tgcggctcga
    15841 ttcttgagca cattaggccg ctttaaaata tctaaggcct catccacaac ttcctgtgct
    15901 tctgtctcca tcaagccacc actagccgct tgtttcagac tcaggtttaa tccggtcaaa
    15961 ataaacagaa tctgatttcg ttgcaccata ttcatgagcg atcctccatg tctggtagat
    16021 aaatgtttgc aatgagataa tgttttcttg aattgctaac tgcaatatac caaatctatc
    16081 aagcttcggg tcaaactttc gataaacgtc gccttttcgc cgattaacgt tattgcggac
    16141 atgaatcgcc cggtccaaag cacatagaaa aagccgtggt gcattaacca cgactaatcg
    16201 gaagcgcgta tttcagcata gtcgtaaaaa ggctgaaatg acacagttca tcagcatcaa
    16261 acaaattcat attccatccg gctacttaat gtccgccacc ccagacaatt ggaaaggcga
    16321 cgagcccagc agccagcgcc tgatcgcgat aacgcttggc attgacctga tctgccggca
    16381 catccgcctt gatcgcattg aaaatggcga tcatctcgtc tggaatcgtg tgatgaatga
    16441 gataatactt ggaaatatca tgcgatagct gggtcacgac tgcgacataa gttgttttat
    16501 cctctgcatc ttccagttgt ttcgcgttgg attcgattat ttgctttaat ttggcatcag
    16561 ctttcacgg
//
