LOCUS       gnlProkkaGGBCAPOO_135  12801 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GGBCAPOO_135.
ACCESSION   gnlProkkaGGBCAPOO_135
VERSION     gnlProkkaGGBCAPOO_135
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:16:42
            Original ID  :: gnl|Prokka|GGBCAPOO_135
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 12801
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..12801
                     /aStool="rule-based-clusters"
                     /category="PKS"
                     /contig_edge="True"
                     /core_location="[10166:11324]"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      10167..11324
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /neighbourhood="20000"
                     /product="T3PKS"
                     /protocluster_number="1"
     cand_cluster    1..12801
                     /SMILES=""
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /kind="single"
                     /product="T3PKS"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..12801
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="T3PKS"
                     /region_number="1"
                     /rules="(Chal_sti_synt_C or Chal_sti_synt_N)"
                     /tool="antismash"
     CDS             complement(93..230)
                     /locus_tag="ctg88_1"
                     /transl_table=11
                     /translation="MGLVTRRSEQLDKLFDQFAIDPKKPKATKKNDDKKEKDSKDKEKK
                     "
     CDS             374..2185
                     /locus_tag="ctg88_2"
                     /transl_table=11
                     /translation="MASEHLEHKLALLPDKPGCYLMKNINDQIIYVGKAKNLKNRVRSY
                     FKSSHTGKVAKMVSEVADFETIVTSTNKESFLLEITLIQKHQPYFNIKLKKGTGYPYIK
                     ITNERDPQIKIVSKIKKDGGYYFGPYPNVYAAEETMHFIQKVYPLRRCNGYQGRPCLYY
                     HMGQCLGACFKEVPKSDYEEQIKKIKSFLSGNTATVKRQLTKKMQRAAENMEFERAAEI
                     RDQLHYIEVTVEKQKIISNDKTPRDLFNFYMDKGWLSIQIFFIRQARLMKREKRLFPIV
                     DTAVEEMTSFILQFYNRRNNILPHEILLPKGLPNKEISEILGVPVRTPVRGEKRDLLAM
                     AHENAQLSLDEKFRLLEMDQSKTTGAMKEITDALGLPEGHRIEAFDHSHIQGADPVSAM
                     VVFINGEPAKNFYRKYKLKTVINHADEAASTREVIRRRYSRLLKENKPMPDMIFMDGGE
                     IQMDAAKDVLENELGLEIPVVGMVKNDKHQTADLLFGDDDHHINLNPRSQGFYLVQRIQ
                     DEVHRFAITFHRRVHTKHSLSSRLDEIKGVGPRTRTKLLKKYGSITKIAQASVDEIHSL
                     GINRPTAQLIKVSLQKNAEVAKGSSHD"
     CDS             2250..3566
                     /locus_tag="ctg88_3"
                     /transl_table=11
                     /translation="MNMFVDQIKIEVHAGKGGDGMVAFRREKYVPNGGPAGGDGGRGGS
                     IILKVDEGLRTLMDFRYHRIFKAKNGGNGMSKQMTGPSAEDTIIAVPQGTTVRDLDTGE
                     IIGDLVEKDQELVVAKGGRGGRGNIHFASAKNPAPEIAENGEPGEDHYLELELKMLADV
                     GLIGFPSVGKSTLLSVVTGAKPKIAAYEFTTLTPNLGMVMLPDGRDFAMADMPGLIEGA
                     SKGIGLGLKFLRHIERTRVLLHLVDMSSEDPHQAIERYRQINKELADYDPELLKRPQIV
                     VATKMDLPNSADNLAAFKADLAADKTLEKQPEIFPISAVTHQGVQQLMQLTADLLDKTP
                     AFDSESHDKELVAEYRAAAPDKKDEADFTITKDEDGTWVLGGEKLIRLFKMTDLTHEES
                     QLRFARQLRHMGVDDALRAKGVQDGDLVRIEKFVFEFIQ"
     CDS             3599..4528
                     /locus_tag="ctg88_4"
                     /transl_table=11
                     /translation="MQLEFLGTGAGSPSKQRNVASVALRLLEERNAIWLFDVGEATQHQ
                     ILNTTIRPRKIEKIFITHLHGDHIFGLPGLLSSRSFQGGTEPLTIYGPVGIKRYVQTSL
                     QVSESRLSYPLHFVEITDDGELFNDHGFRVIARKLDHKIACFGYRIEEADHPGELQVEK
                     LREQKVPSGPIYGQLKAGKTVTLPDGRVLDGHDFIGTPQPGRIIAILGDTRQTKNAILL
                     AQNADVLVHESTFAKDETKMAHNYYHSTSKQAAEIAKKAGVKKLLLNHISARYTGKAAY
                     QLAYQVRNIIPDTRVVNDFDVIDIPFKK"
     CDS             4525..5379
                     /NRPS_PKS="Domain: PKS_KR (21-175). E-value: 5.7e-11.
                     Score: 34.5. Matches aSDomain:
                     nrpspksdomains_ctg88_5_PKS_KR.1"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) adh_short"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1001:short-chain dehydrogenase/reductase SDR (Score:
                     187.6; E-value: 4.5e-57)"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg88_5"
                     /sec_met_domain="adh_short (E-value: 3.2e-33, bitscore:
                     105.0, seeds: 230, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRDGKKMLRRVKTLRFLRNEVVLITGGSSGIGKQLAFEAARRGA
                     IVVVVSRNLEKLQEVAKKCLILSGRPAFAYQLDVTDPDQIDDVLSKVQHEVGGIDVLIN
                     SAGLGDFIPVVKESYRSMEKMVHTNLLALMYISRCVAKQMMDQGYGAIINMGSLAGKLP
                     TPNSAVYSATKAGVIQFDNVLRMEVADYGVQVLTVNPGPIDTPFFDKADNDYTYQAHLP
                     KWVFISPEDLARRIWNNVGYKTREINVPGYVAYLGWAYQVIPGLGDWAIKKFFDFQQDK
                     KNL"
     CDS_motif       4588..4734
                     /aSTool="nrps_pks_domains"
                     /database="abmotifs"
                     /detection="hmmscan"
                     /domain_id="nrpspksmotif_ctg88_5_0001"
                     /evalue="2.70E-05"
                     /label="PKSI-KR_m1"
                     /locus_tag="ctg88_5"
                     /protein_end="70"
                     /protein_start="21"
                     /score="16.8"
                     /tool="antismash"
                     /translation="VVLITGGSSGIGKQLAFEAARRGAIVVVVSRNLEKLQEVAKKCLI
                     LSGR"
     aSDomain        4588..5049
                     /aSDomain="PKS_KR"
                     /aSTool="nrps_pks_domains"
                     /database="nrpspksdomains.hmm"
                     /detection="hmmscan"
                     /domain_id="nrpspksdomains_ctg88_5_PKS_KR.1"
                     /evalue="5.70E-11"
                     /label="ctg88_5_PKS_KR.1"
                     /locus_tag="ctg88_5"
                     /protein_end="175"
                     /protein_start="21"
                     /score="34.5"
                     /specificity="KR activity: inactive"
                     /specificity="KR stereochemistry: C2"
                     /tool="antismash"
                     /translation="VVLITGGSSGIGKQLAFEAARRGAIVVVVSRNLEKLQEVAKKCLI
                     LSGRPAFAYQLDVTDPDQIDDVLSKVQHEVGGIDVLINSAGLGDFIPVVKESYRSMEKM
                     VHTNLLALMYISRCVAKQMMDQGYGAIINMGSLAGKLPTPNSAVYSATKA"
     CDS             5519..7846
                     /locus_tag="ctg88_6"
                     /transl_table=11
                     /translation="MIDAKFKWKLADNASSATVDNLEKELGISRILATLLAQQGIDSTE
                     QAKKFFEPSMEEIHDPTLLHDMDKAVERIEQAVEKQEQITIYGDYDADGITSTSLMYET
                     LLSIGANVNYYVPNRFTDGYGPNMDAYQRLIDNGTQLFITVDNGVSGKNVIDKVMAAGV
                     DVVITDHHELPADLPNAVAIVHPRYPGSNYPFPDLSGVGVAFKVAWALTGEFPIEELDL
                     VAIGEIADVVNVTDENHTLISYGIQQLRQGMRPGLAALMKLADIKANNLTDQDIGFGIA
                     PRLNALGRIADANDGVKLLTSLDENESQKLAKEVDQANKERQNLVADIMKEAEKQANSS
                     ANQQKKTLLIVGKGWHQGVLGIVASRIMNETGKPTIVASTDQNNPTLIKGSGRSVDSFN
                     LFNALEAHRELFTTFGGHPAACGLSFDSKNIVPLQIALEEEAVKQKFDPTVKQPLPIAM
                     QLEPADVTQQLYNDIQRVAPFGPGNMEPVFELNNVKVVDVKTMGQEHQHLKFSIVSGKE
                     NLTVVAFGQGNLATLLSAPTGQVNLAVKVSLNEWRGKKSVQLMLEDLQINGTVIIDERT
                     NKLTPQLFSSSDYYIVREPRLRDNIAPHVAPGYTLSIEEAIKTDFSGQRVTLVDCPSSE
                     EMLKQIFAEDEGEPATIRLLLYQRKSAYLAGLPTRNDFAQLYRFIYKQKELKWPIQAKA
                     VSNQLKINMDRLNLMIQVFSEAGFVTIKDDVLKFNEPTNKTDLTQTKRYQKQLAQYRVE
                     QQLLFNDAATVANWLLKYLNLE"
     CDS             7863..8381
                     /locus_tag="ctg88_7"
                     /transl_table=11
                     /translation="MALDLYKYVASVPDYPEKGIIFRDILPLMADGAAFKQATDELVDY
                     AKDKKVDMVVGPEARGFIVGCPIARELGVGFAPARKKGKLPRKAISASYDLEYGTATLQ
                     MEADAIKPGQRVLVVDDLLATGGTISATIDMVEQMGGIVVGCAFLIELKDLHGRDKLKD
                     YDMKALMEF"
     CDS             8492..9106
                     /locus_tag="ctg88_8"
                     /transl_table=11
                     /translation="MIFLVIMGALFLILGGFYLANSWQQYREWKSGTIIVVLSIIAIVY
                     GVINLPYFHHSNSASSSQSTSSSQVARSSSFSSFSNGLTIGNSSANEAQQESKTMAVLR
                     QMQKGYSKLGSVDYNEDSKTFQITPTDDNTVEALKALAQDPSQAEQMGWPNLTKSIKSN
                     SGQVEKALGEGYSISIMNPSDSSKALYTAKDGKTTYDIANQ"
     CDS             9473..10141
                     /locus_tag="ctg88_9"
                     /transl_table=11
                     /translation="MVKKYYAVKKGRHPGIYKTWAECQKEVNGYPNAKFKSFLTLKGAN
                     EWLQATGNTVPSTKAVDHSDNILVYTDGGSRNHGNKLGQHVKADDKAAWAYFIQTKDQA
                     YTGTAGEFGATNNKMEITALIQALTKLLELGLQDQPITAILDSHYVLDPIMKGWLTNWQ
                     RRGWLTASGKPVANQKLWEEIVTLLPQFPNLHFDWTKGHATNAGNNKVDELLNKTMDQL
                     "
     CDS             10167..11324
                     /gene_functions="biosynthetic (rule-based-clusters) T3PKS:
                     Chal_sti_synt_N"
                     /gene_functions="biosynthetic-additional (smcogs)
                     SMCOG1043:hydroxymethylglutaryl-CoA synthase (Score: 535.1;
                     E-value: 1.5e-162)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg88_10"
                     /sec_met_domain="Chal_sti_synt_N (E-value: 4.7e-09,
                     bitscore: 25.8, seeds: 21, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MRIGIDKMAFATTNDYLDLVELAKERGVDPNKFTIGIGQDLQAVV
                     PPTQDIVTLGATAAKKLLTPELEKNISTVIVATESGIDNSKASAIYIKHLLGLSDFIRT
                     VEMKEACYSATAAIQFAKGVVALNPQETVLVIAADIARYGLNTPGEVTQGAGAVAMLIS
                     QNPHILTLEDTTVAYSKDIMDFWRPLYATEALVDGKYSTNVYIEFFLQTFTRYQQLTGR
                     ELADFAALTFHMPFTKMGKKGLEGLLKDRNDEVAQRLRTQLTASQLFSRQVGNLYTGSL
                     YLSLMSLLQNSDLRAGSRIGLFSYGSGAEGEFYTGILEDGYEHYMNNIQEELKHRHQVS
                     VAEYEKLFSSQLGMNDRDIEFDVADDPLPFVLKGQKDHQRIYEAK"
     CDS             complement(11366..11992)
                     /locus_tag="ctg88_11"
                     /transl_table=11
                     /translation="MAKLAKNKQMAVLNYIHKQVEDHGYPPTVREICSAVGLSSTSTVH
                     GHISRLIEQGFLQKDPSKPRALEITPKGLDILGVKPIQKEIPMLGVVTAGQPILAVENA
                     TEFFPIPPSIQDNNDLFMLTIRGTSMIKAGIFNGDQVIVRKQSTAKNGDIVIAMNDDNE
                     ATCKRFYKEKTRFRLQPENDTMEPIFLDNVKILGKVVGLFRDHIF"
     CDS             12112..12372
                     /locus_tag="ctg88_12"
                     /transl_table=11
                     /translation="MIIMAESKEQDALLKRINELAHKNKEEGLTEEETKERDRLRKEYL
                     KNFREAMRSNIEMMRIFDKEGKEVTPEKVREIQRKKGLRDD"
     CDS             12452..12673
                     /locus_tag="ctg88_13"
                     /transl_table=11
                     /translation="MTIMLMILALLVGLVIGFFGARKYMENYLRNNPPISEEMLRTMML
                     QMGQKPSSRKLHQMMQAMKAQAKKSNRK"
ORIGIN
        1 agtgattaag ttgtcgaacc gccgtatacg gaaccgtacg tacggtggtg tgagaggtcg
       61 ataattgaac taatcaatta tctcctactc gattatttct tttctttatc tttactatct
      121 ttttcttttt tatcgtcatt ttttttagtt gcttttggtt ttttaggatc aatcgcaaat
      181 tgatcaaata atttatcaag ctgttcgctt cttctagtaa ctaatcccat ttttttagct
      241 ccttttttat atttgacaaa atgctagcat aaattttgct aaatgtacaa ttatttctaa
      301 acactttctt tgccttaatg atgatttttc agatataata tattgttaga taatttttcg
      361 gagggatttt gcgatggcca gtgaacattt agaacataaa ctagcattgt tacctgacaa
      421 gccaggttgc tacctgatga aaaacattaa tgatcagata atttatgttg gtaaagctaa
      481 aaatttgaag aatcgggttc gctcttactt taagagtagt cacaccggta aagtagctaa
      541 aatggtttcg gaagttgcag actttgaaac cattgtaact tcgactaata aagagtcgtt
      601 cttactcgaa ataacgctga ttcaaaaaca tcaaccttat ttcaatatca aattaaaaaa
      661 gggaactggt tatccctaca taaaaataac aaatgagcga gatcctcaaa ttaagatcgt
      721 tagtaaaata aaaaaagatg gtggatatta ttttggccct tatccaaatg tctatgctgc
      781 ggaggaaacg atgcatttta ttcaaaaggt ttacccatta agacgatgta atgggtacca
      841 aggccgtccg tgtttgtatt accatatggg acaatgttta ggagcttgtt ttaaagaagt
      901 tcctaagagt gactacgaag agcaaattaa gaaaattaag tcatttttga gtggaaacac
      961 agcgacagtt aagcgacagt taaccaaaaa gatgcaacga gcagcagaaa atatggagtt
     1021 tgaacgagcg gctgaaattc gagaccagct tcactatatt gaagtaacgg ttgaaaaaca
     1081 aaagattatt tcaaatgata agacccctcg tgatttgttt aatttctata tggataaagg
     1141 gtggctttct attcaaattt tctttatccg acaagcacgg ttaatgaaac gagaaaaacg
     1201 tctatttcca atcgtggata cggcagtcga agaaatgacc agctttattc ttcaatttta
     1261 taatcgtcgt aataatattt tgccgcatga aattctcctt cccaagggtc tccctaataa
     1321 agaaataagt gaaatactag gggtgccggt tcggacacct gttcggggag aaaaacgaga
     1381 tctcttagca atggcacatg aaaatgctca gttgtcctta gatgaaaaat ttcgactgct
     1441 tgagatggac caaagtaaga ctaccggtgc gatgaaagag attacggatg cccttggact
     1501 tccagaaggt caccggattg aagcatttga tcattctcat attcaggggg ctgaccccgt
     1561 cagtgcaatg gttgtattta ttaatggaga accggctaaa aatttttacc ggaagtataa
     1621 attgaaaacg gtgattaatc atgctgacga agctgccagt acccgtgaag ttattcggcg
     1681 gaggtattcg cgtctcttaa aagagaataa gccaatgccg gatatgattt ttatggatgg
     1741 tggcgaaatt cagatggatg cggctaaaga tgttttagag aatgaacttg gtctcgagat
     1801 tccggtagta gggatggtaa agaatgataa acaccaaacc gctgacttat tgttcgggga
     1861 tgatgatcac catattaatt tgaatccacg gagccaaggc ttttacttag ttcaacgcat
     1921 tcaagatgag gttcaccggt ttgcgattac tttccaccgg cgcgttcata ctaagcattc
     1981 gttgagctcg cgtttggatg aaattaaggg agtgggaccc cgaactcgaa caaaattgct
     2041 taaaaaatat ggatcaatta ccaaaattgc tcaagcctca gttgatgaaa tccattcact
     2101 aggaattaat cgacctaccg cccagttaat caaggtttca ttgcagaaaa atgctgaggt
     2161 ggcgaagggt agtagtcatg attgagtttt gacaggctta taaattttaa atatactaaa
     2221 taatagacta aagaacggag acaatcatta tgaatatgtt tgttgatcaa ataaaaattg
     2281 aagtacatgc aggtaagggt ggcgatggaa tggtagcatt tcgtcgtgaa aaatatgttc
     2341 ctaacggggg cccagctggt ggcgatggtg gccgtggcgg tagtatcatt ttaaaagttg
     2401 atgaaggatt acggacatta atggatttcc gttatcaccg aatttttaaa gctaaaaacg
     2461 gtggcaatgg gatgagtaaa cagatgactg ggccaagtgc agaagataca attattgctg
     2521 ttccccaagg taccactgtt agggatcttg atactggcga gattattggt gatctcgttg
     2581 aaaaagacca agaattagta gttgccaaag gtggccgtgg tggtcgcggc aacattcact
     2641 ttgctagtgc taaaaaccct gctcctgaaa ttgctgaaaa tggtgaacca ggagaagacc
     2701 attacttaga attagaatta aagatgcttg ctgatgtcgg attaattggg ttcccttctg
     2761 ttggaaagtc aactttatta tcagtagtaa ccggtgctaa gcctaaaatt gctgcatatg
     2821 aatttacgac attaactcct aatctcggaa tggtaatgct accagatggc cgtgattttg
     2881 cgatggctga catgcctggt ttaattgaag gagcatcgaa gggtatcggc cttggattga
     2941 agttcttgcg gcacattgaa cgtacccgcg ttcttcttca cctagtggat atgagtagtg
     3001 aagatcctca tcaagcaatt gaacgttacc ggcaaattaa taaggaactt gctgattacg
     3061 atcctgaatt attaaagcga ccacaaattg tagttgcgac gaagatggat ttgccaaatt
     3121 ctgccgataa cttagccgct tttaaagctg atttggcagc agataagact ttagaaaaac
     3181 agccagagat tttccctatt tcagcggtta ctcatcaagg tgttcaacaa ttaatgcaat
     3241 taactgctga tctcttagat aagacgcccg catttgatag tgagagtcat gataaagaat
     3301 tggtcgctga atatcgtgct gctgctcctg acaagaaaga tgaagcggac tttaccatta
     3361 ccaaggatga agacggcacc tgggtattgg gtggtgaaaa acttattcgg ttatttaaga
     3421 tgactgattt aactcatgaa gaaagtcaat tacgctttgc tcgtcaactt cgccatatgg
     3481 gggttgatga cgcgttaaga gctaaaggtg tacaagatgg cgatcttgta agaattgaaa
     3541 aatttgtttt tgaatttatt caataaaatt atacgtagca aaggtaggaa aaatataaat
     3601 gcaacttgaa tttttaggaa caggcgctgg ttccccaagt aagcaacgta atgtagcaag
     3661 tgttgcattg cggttgttag aagaacgaaa cgcaatttgg ttatttgatg ttggagaagc
     3721 tactcaacat caaattctca atacgacaat taggccacga aagatagaaa aaatctttat
     3781 tactcacttg catggtgatc atatctttgg tttacctggt ttactaagtt cccgctcttt
     3841 tcaaggagga accgaaccat tgacgatcta tggaccagta ggaataaagc ggtatgttca
     3901 gacttctttg caagtaagtg agtcacgcct cagttatcct ttgcattttg ttgaaataac
     3961 agatgacggg gaactattta atgatcatgg ttttagagtg attgcacgaa agttggatca
     4021 caaaattgct tgttttggat accggattga agaagcggat catccaggag aattacaagt
     4081 tgaaaaatta cgagaacaaa aagtaccatc tgggccaatt tacggccaac taaaagctgg
     4141 aaaaacggtt actcttcctg atggtcgcgt attagatggt catgacttta ttggcactcc
     4201 tcaacctgga cgcattattg caattttagg cgatactaga caaacaaaga atgcaatttt
     4261 gttagcacaa aatgcggatg tattagtgca tgaaagtact tttgctaaag atgagacgaa
     4321 gatggcacac aattattatc attcaaccag caaacaagca gctgaaattg caaaaaaagc
     4381 tggtgttaaa aaattattgt taaatcatat ttcagcacga tacaccggta aagcagccta
     4441 tcaattggca tatcaagttc gtaatattat tcctgatact cgagttgtta atgattttga
     4501 cgtgattgat attccgttta aaaaatgaaa agagatggca aaaaaatgct gagaagagta
     4561 aagacgttac gttttctgcg aaatgaagtt gtattaatta ctggtggttc aagtggaatc
     4621 ggcaaacagt tggcttttga ggcagctcgt cgcggcgcaa ttgttgttgt tgtttctcgt
     4681 aaccttgaga agttgcaaga ggtagccaag aaatgtttaa ttttatctgg tcggccagca
     4741 tttgcttatc aattggatgt caccgaccct gatcagattg atgatgtgct ttcgaaggtt
     4801 caacatgaag taggaggaat cgatgtatta attaattctg ctgggcttgg tgactttatt
     4861 cccgtagtta aggaatctta ccgctcaatg gaaaaaatgg tacatacaaa cctcttagcc
     4921 ttaatgtata ttagtcggtg tgtggctaaa caaatgatgg atcaagggta tggggccatt
     4981 attaatatgg gttcattagc tggtaaattg cctacaccaa atagcgctgt atattcagca
     5041 acgaaggctg gggtaatcca gtttgataac gttttacgaa tggaagttgc tgattatggt
     5101 gtccaagtgt tgacagttaa tcctggtcca attgatacgc ctttctttga taaagcggat
     5161 aatgattata catatcaggc acatttgcca aaatgggtgt ttatctctcc tgaagactta
     5221 gctcgacgaa tttggaataa tgtcgggtat aagacaaggg aaattaatgt tccaggatat
     5281 gtggcttatc ttggctgggc ttaccaagtt attcccggtt taggtgactg ggcaattaag
     5341 aaattttttg atttccaaca ggataagaag aacttataat atgctccctt atttttattt
     5401 tcgttaaatt gcagaattta gcagtttctt tcaaaaaatg aaaggagcaa aataaaagag
     5461 actgagttta tcccagcctc ttgtttaatt ttggcgttga aatggtggtt aattttaaat
     5521 gattgatgca aaatttaagt ggaaacttgc cgataatgct tcctcagcaa ctgttgataa
     5581 tctcgaaaaa gagttaggca tttctagaat attagcaacc ttattagctc agcaaggaat
     5641 cgattcaacc gaacaagcaa aaaaattctt tgaaccatcg atggaagaga ttcatgatcc
     5701 aaccttattg catgatatgg ataaggcagt tgagcggatt gagcaggcag ttgaaaagca
     5761 agaacaaatt actatttatg gtgattatga tgccgatgga attactagca catccttaat
     5821 gtatgaaaca ttattatcta tcggtgctaa tgttaattat tatgtcccaa atcggtttac
     5881 agatggatat gggcccaata tggacgctta ccaacgcctt attgataatg gtacccagct
     5941 ttttattacg gtggataatg gcgttagcgg aaaaaatgtt atcgataagg taatggcagc
     6001 aggagtagat gttgtaatta ctgaccacca tgagttgcct gctgacttgc ctaatgctgt
     6061 tgcgatcgtt caccctcgct atcctggtag taattatcct tttcctgatt tgtcaggtgt
     6121 tggtgtcgca tttaaggtgg cctgggcttt aactggtgag tttcctattg aagaactgga
     6181 cttagttgca attggtgaaa tagctgatgt agtaaacgtt acggacgaaa atcatacgtt
     6241 aatttcctat ggcattcagc aattacggca ggggatgcgt ccaggattag cggctttaat
     6301 gaaattagct gatattaaag ctaacaatct aactgatcag gatattggat ttggaattgc
     6361 accacggcta aatgcgcttg gccgaattgc tgatgctaat gatggagtta aattactgac
     6421 gagtttagat gagaatgaat cacaaaaatt agctaaagag gtcgatcagg cgaataaaga
     6481 acgtcagaac ctagttgctg atattatgaa agaggcagaa aaacaagcta atagttcagc
     6541 taaccagcag aaaaagacct tattaattgt tggaaaaggt tggcatcaag gcgtattagg
     6601 aattgttgcc agtcggatta tgaatgagac tggaaagcca acaattgtcg catcaactga
     6661 tcaaaataat ccgaccttaa taaaaggatc tggtagaagc gttgacagtt ttaacctgtt
     6721 caatgccttg gaggctcatc gtgaactatt tacgacattt ggcgggcacc ctgctgcttg
     6781 tggcctttct tttgattcga aaaatattgt acctctgcaa atagccttgg aagaagaagc
     6841 agtcaaacaa aaatttgatc caacggtaaa gcaacctctt ccgattgcaa tgcaacttga
     6901 gccagctgat gttacccaac agttatataa cgatattcaa cgggttgctc catttggccc
     6961 aggaaatatg gaaccagttt ttgaattaaa taacgttaaa gttgtcgacg ttaaaacaat
     7021 ggggcaagaa catcagcact taaaattttc gattgtaagt ggtaaagaaa atctaacggt
     7081 cgttgctttt ggtcaaggaa atttggcaac actattatct gcgccaaccg gacaagttaa
     7141 tttagctgtt aaagttagcc tcaatgagtg gcgtggtaaa aaaagcgtcc aactgatgct
     7201 agaagacctg caaatcaatg gaacagtaat tattgatgag cgaacgaata aactaactcc
     7261 tcagcttttt agttcttcag attattacat tgtaagagaa ccaagattac gagacaacat
     7321 tgctcctcat gtggcccctg gctatacttt atcgattgaa gaagcaatta agactgattt
     7381 ttccggtcaa cgagttacgt tggttgactg tccatcgagt gaagaaatgc taaaacagat
     7441 ttttgcagag gatgaagggg agccagcaac tattcgctta ttactatatc agcgaaaaag
     7501 cgcttattta gctggacttc caacacggaa tgattttgca cagctttatc gatttattta
     7561 taagcaaaaa gaattaaaat ggccaatcca agctaaagca gttagcaatc agttaaaaat
     7621 taatatggat cgattaaatc taatgattca agtgttttct gaagcaggat ttgttacaat
     7681 aaaagatgac gtgttaaagt ttaatgagcc aactaataag actgatttaa cacaaactaa
     7741 acgttatcaa aaacaattag cacaatacag agttgagcaa cagttgcttt ttaatgatgc
     7801 ggcaacggtt gctaactggt tattgaaata tttaaattta gaataaggag actatttatc
     7861 tcatggcttt agacctttat aaatacgtag ctagtgttcc tgattatcca gaaaagggta
     7921 ttatctttcg agatattttg ccattaatgg cggatggagc tgcctttaag caagctactg
     7981 acgaattagt tgattatgct aaggataaaa aggtagatat ggtagtaggc ccagaagcgc
     8041 ggggctttat tgttgggtgt cctattgctc gcgaattagg tgttggattt gctccagcac
     8101 gtaaaaaggg taagttgcca agaaaagcaa ttagtgcatc ttatgactta gaatacggaa
     8161 cagctacctt gcaaatggaa gccgatgcaa ttaaaccagg acaacgggtt cttgttgtgg
     8221 atgatctctt agctacagga ggaacaatct ctgcaacaat tgatatggtt gaacaaatgg
     8281 gtggtattgt tgttggctgt gcattcttaa tcgaattaaa agatcttcat ggtcgtgata
     8341 agcttaaaga ttacgatatg aaggcattaa tggaatttta attaggagga ggctggggat
     8401 actagccttt tttcttttta aattgcagtt gtatatataa aatgaatgcg ggacaataac
     8461 attacgttga taaaaaggag ccagttaatt tatgattttc ttagtaataa tgggagccct
     8521 atttttaatt ttgggtggtt tttatcttgc taattcatgg caacagtacc gtgaatggaa
     8581 aagtgggaca atcattgttg tattgagtat tatcgcaatt gtttatggtg tgattaattt
     8641 gccttatttt catcatagta attctgctag ctcaagccaa agtacttcat cttcacaagt
     8701 ggcgcggtcc agtagctttt catcattttc aaatggattg acaattggta attcaagtgc
     8761 aaatgaagca caacaagaaa gtaagacaat ggctgttttg cgtcaaatgc aaaagggtta
     8821 ttcaaaatta ggttcagttg actataacga agatagtaag acattccaga tcacgccaac
     8881 tgatgataat acagttgaag cattgaaagc tttagcgcaa gatccaagtc aggctgaaca
     8941 aatgggttgg cctaacttaa ctaagtcgat taaaagtaat tcagggcaag tagaaaaagc
     9001 attaggtgaa ggatattcaa ttagcattat gaatccaagt gattctagta aggcgttgta
     9061 tactgctaaa gatggcaaaa ctacatacga tattgctaat caataaaact aaataaccta
     9121 agattagttc aagacagatt agggcactta ataggtgtcc ttttttgtgt aataaaaaag
     9181 ctgatatacc aacgttttaa caactattga atatcagcaa aactttagat aaaggagaca
     9241 aggggatttg aacccctgca cgcttttaca cgcctaacgg ttttcgaaac cgtcctcttc
     9301 agccacttga gtatgtctcc atttcaactt tatcattgta acaaaaaaat tgtaaagcgt
     9361 aaagagaata tcaatcaagg aaatagctat ttaataattt tgcagaaatg atttcttgct
     9421 gatatgatat tctaatatat gatgtaattt gaaatttgat taggggattt ttatggtaaa
     9481 aaaatattat gcagtcaaaa aaggtcgtca tccgggaata tataaaactt gggctgaatg
     9541 tcagaaggaa gttaatggat atccaaatgc taagttcaaa agttttttaa cacttaaagg
     9601 tgctaatgaa tggcttcagg ctacgggaaa taccgtgccc tcgactaaag cagttgatca
     9661 ttctgataat attcttgttt atactgatgg aggctcccgt aatcatggca ataagttggg
     9721 gcagcatgtt aaggcagatg ataaagcagc ttgggcttat tttattcaaa ctaaagatca
     9781 agcttataca ggaacggctg gcgaattcgg ggctactaat aataaaatgg agattacagc
     9841 tttaatccaa gcgttaacta aactattaga acttggcctc caagatcaac caattacagc
     9901 gattttggat tcacattacg tactagaccc aattatgaaa ggctggttaa ctaattggca
     9961 acggcgggga tggttaactg ctagtggcaa gccggtagca aatcagaagc tatgggaaga
    10021 aatagttacc cttttacctc aattccctaa tttacatttt gattggacta agggtcatgc
    10081 aacgaatgct ggaaataata aggtcgatga attactaaat aaaacgatgg atcagttata
    10141 attatttgac aagaggatga taagaaatga gaattggtat tgacaaaatg gcttttgcaa
    10201 caacaaatga ttatttagat cttgttgaat tagcaaaaga acgcggcgta gatcctaata
    10261 aatttaccat tggaattgga caggatctac aggcagttgt gccacctacg caagatattg
    10321 tgactttagg agctacggca gcgaaaaaat tgcttactcc agaattagaa aaaaatattt
    10381 cgacagtaat tgtggcaact gagtcaggga ttgacaattc aaaagcaagt gcaatctaca
    10441 ttaaacactt attaggactt agcgacttta tccgaacggt agaaatgaaa gaggcatgtt
    10501 attctgcgac agctgctatc caatttgcaa agggggtagt ggcgcttaat cctcaagaaa
    10561 ctgtattggt gatcgctgct gatattgctc gttatggatt aaatactcca ggagaggtga
    10621 ctcaaggagc tggagcagtt gcaatgctga tttcacagaa ccctcacatc ctaacccttg
    10681 aagatacaac tgtcgcttat agcaaagata taatggactt ttggcggccg ttatatgcaa
    10741 cagaagcttt agtagatgga aaatactcta ctaatgttta tattgaattt ttccttcaaa
    10801 cttttacccg ttaccagcaa ttaactggtc gagaattagc agattttgct gcccttacat
    10861 tccatatgcc atttactaaa atgggaaaga aagggttaga agggttgctt aaagatcgta
    10921 atgatgaggt agctcaacga ttacgaacac aattaaccgc aagtcagcta ttttcgcgtc
    10981 aagttggcaa tctttacact ggctccctat atttatcatt aatgtcattg ttacaaaata
    11041 gtgacttaag agctggaagc cgaattgggt tatttagcta tggttctggt gcagaaggag
    11101 agttctacac aggaatccta gaagatggct acgagcatta tatgaataat attcaagaag
    11161 aactaaaaca tcgtcatcag gtttcggtgg cagaatacga aaaactattt agtagtcaat
    11221 taggaatgaa tgatcgggat atcgaatttg atgttgctga tgatccattg cctttcgttc
    11281 ttaaaggaca aaaagatcac caacggattt atgaagctaa ataacctaat aaaaaaggag
    11341 cccccaaaat ggactccttt tttatttaga aaatatgatc acgaaatagt cccactactt
    11401 taccaaggat tttaacattg tctaagaaga ttggctccat cgtatcattt tctggctgta
    11461 aacgaaaacg tgttttttct ttatagaatc gtttacaagt agcttcatta tcatcgttca
    11521 ttgcaataac gatatcacca tttttagcag tggattgttt acgcacgatt acttggtcgc
    11581 cattaaaaat ccctgcttta atcatactag ttccgcgaat ggtaagcata aacaaatcat
    11641 tattatcttg aatagaagga ggtatcggga aaaactcagt agcattttcg actgctaaaa
    11701 ttggttgtcc agccgtaaca acaccaagca ttggaatttc tttttgaatc ggttttacac
    11761 ctaaaatatc aagtcccttg ggtgtaatct caagtgctcg aggcttagaa gggtcttttt
    11821 gtaagaatcc ttgttcaatt aagcgggaaa tgtgtccatg aactgttgaa gttgaagaca
    11881 ggccaacagc actacaaatt tcacgaacag ttggtggata gccatgatct tcaacttgtt
    11941 tgtgaatata atttaggacg gccatttgtt tattttttgc tagctttgcc atattgacac
    12001 ctcattatca ttaattgtgt taagcttatc atagatagat gcatatttca aacgtacgtt
    12061 cgcgatttgc attgatttta taaaataagt aaaatcgact ttattaagga gatgattata
    12121 atggctgaat ctaaagaaca agatgcttta ttgaagcgaa ttaatgaact tgctcataag
    12181 aataaagaag aaggtttaac tgaagaagaa acaaaagaac gagatcgttt acgtaaggag
    12241 tacctaaaga actttagaga agcaatgcgt agtaatattg aaatgatgcg gatctttgat
    12301 aaagaaggga aagaagttac tcctgaaaag gttcgtgaaa tccaacgtaa aaaaggactt
    12361 cgtgacgatt aacagcgatt tgctcttttc aaaaattgct ctttcgtgta agatggatag
    12421 gtaacgagca aaggaggaag taattgtggg tatgacgatc atgctaatga ttcttgcatt
    12481 attagtcggt ttggttatcg gcttctttgg tgcacgtaaa tacatggaaa actacctccg
    12541 caataatcca ccgatttcgg aagagatgct gcggacgatg atgcttcaaa tgggacaaaa
    12601 accatcaagt cgtaaattac atcaaatgat gcaagcgatg aaagcacaag ctaaaaagtc
    12661 gaatcgtaaa taatataaaa ggatgtgata attatcacat ccttttatat taatgtcttt
    12721 agacctagtt gagtgcgcga gcagagcgag tgcacgaaac aaaaaaccac ctgctatgcg
    12781 ggtgggcgat aaaaattata t
//
