LOCUS       c00054_gnlPro..        16004 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|HKFGBFPE_102.
ACCESSION   c00054_gnlPro..
VERSION     c00054_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-30 15:15:08
            Original ID  :: gnl|Prokka|HKFGBFPE_102
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 16004
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..16004
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[145:6004]"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      146..6004
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /neighbourhood="10000"
                     /product="Nitrate_reductase"
                     /protocluster_number="1"
     cand_cluster    1..16004
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /kind="single"
                     /product="Nitrate_reductase"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..16004
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Nitrate_reductase"
                     /region_number="1"
                     /rules="(Nitr_red_bet_C and Nitrate_red_del and
                     Nitrate_red_gam and Molybdopterin and minimum(2, [Fer4_11,
                     Molybdopterin, Molydop_binding, Nitr_red_alph_N]))"
                     /tool="gutsmash"
     CDS             complement(146..835)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_gam"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_1"
                     /sec_met_domain="Nitrate_red_gam (E-value: 2.1e-77,
                     bitscore: 250.4, seeds: 140, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MHNGWSIFLWVIYPYIMLASFFIGTFVRFKYFHPSITAKSSELFE
                     KKWLMIGSVTFHIGIILAFFGHCLGMFIPASWTAYFGITEHMYHIFGSLMMGIPAGILA
                     FVGIAILTYRRMTCSRVYKTSDINDIIVDWALLITIALGLACTITGAFIDYNYRTTISP
                     WARSLFVLNPQWQLMRSVPLIYKIHVLCGLAIFGYFPYTRLVHALTLPWQYIFRRFIVY
                     RRRARVY"
     CDS             complement(828..1406)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitrate_red_del"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_2"
                     /sec_met_domain="Nitrate_red_del (E-value: 2.4e-09,
                     bitscore: 28.2, seeds: 108, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VTDFRRLTDLKDTFAVLSRLIDYPDTETFSPEIRQLLLADNALST
                     ATRGELLSLFDELAALSSIEVQEMYAHLFEMNRRYTLYMSYYKMTDSRERGTILARLKM
                     LYEMFGISEATSELSDYLPLLLEFLAYGDYTNDPRRQDIQLALSVIEDGTYTLLKNAVT
                     DSDNPYIQLIRLTRSLIGSCIKMEVREDA"
     CDS             complement(1399..2958)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Nitr_red_bet_C"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Fer4_11"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Fer4_4"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_3"
                     /sec_met_domain="Fer4_11 (E-value: 5.7e-39, bitscore:
                     123.3, seeds: 34, tool: rule-based-clusters)"
                     /sec_met_domain="Fer4_4 (E-value: 0.0009, bitscore: 10.8,
                     seeds: 79, tool: rule-based-clusters)"
                     /sec_met_domain="Nitr_red_bet_C (E-value: 2.8e-28,
                     bitscore: 88.4, seeds: 110, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKIKAQISMVLNLDKCIGCHTCSVTCKNTWTNRPGAEYMWFNNVE
                     TKPGVGYPKRWEDEDQYHGGWTLNSKGKLKLRAGSKLNKIALGKIFYNNDMPELDNYYE
                     PWTYDYKTLFGPEQKHQPVARPKSQITGEGMELTTGPNWDDDLAGSTEYVQQDPNMQKI
                     EGDIKNNFEQAFMMYLPRLCEHCLNAPCVASCPSGAMYKRDEDGIVLVDQERCRGWRFC
                     MTGCPYKKVYFNWKTHKAEKCTFCYPRIEEGQPTVCAETCVGRIRYIGAILYDADRVEE
                     AASTPDESKLYEAQLGLFLDPNDPEVVKQALKDGISEEMIEAAQKSPIYKMAVKEKIAF
                     PLHPEYRTMPMVWYIPPLSPVMSYFEGRDSIKNPEMIFPGIDQMRVPVQYLASLLTAGN
                     VPVIKKALYKLAMMRLYMRAKTSGRDFDSSKLERVDLTEEQATSLYRLLAIAKYEDRFV
                     IPSSQKAEMEDAQTEQGSLGYDECEGCALAPQHKSMFKKAEAGKSTNQIYADSFYGGIW
                     RD"
     CDS             complement(2948..6004)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molydop_binding"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Nitrate_reductase: Molybdopterin"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg54_4"
                     /sec_met_domain="Molybdopterin (E-value: 1.8e-119,
                     bitscore: 390.3, seeds: 32, tool: rule-based-clusters)"
                     /sec_met_domain="Molydop_binding (E-value: 1.6e-23,
                     bitscore: 73.8, seeds: 74, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGGEQMSFYDWYADLPPASPQVWGEQTDVPESAEWYNSSYIIMWG
                     SNVPLTRTPDAHFMTEVRYKGTKIVAVSPDYAENVKFADDWLAPEPGSDSAVAQAMTYV
                     ILDEFYQKHPVKRFIDYSKRFTDLPFMVELEPSTANDAHYTPGRFVRISDLVDDDTIVN
                     PAWKTVVYDQNNHKIVVPNGTMGQEYNAKEKWNLELLDQNGNKIDPALSINDQGEETEQ
                     IIADFPAFSNDGNSVVQRHLPVKKLKFTDGQEHLVTNVYDLMMAQMGINRTGNDELAAK
                     DAMDAESYFTPAWQESRTGVKAEQVIQIAREFAQNAAENEGRSMVIMGGGVNHWFNADM
                     NYRNIINMLMLCGCVGMTGGGWAHYVGQEKLRPQEGWANITFANDWEKGGARQMQGTTW
                     YYFATDQWRYEEIDNQAQKSPVWKSKHSYLHNADYNQMAIRLGWLPSYPQFDRNPLSFA
                     KDYNTTDIDEISKKVVDELKKGTLHFAAEDPDANQNQPKAFFLWRSNLFASSGKGAEYF
                     MKHLLGAENGLLAKPNDRVKPQDMVWRDKGAIGKLDLVVDMDFRMVSTPMYSDVVLPAA
                     TWYEKKDLSSTDMHPFIHPFNAAVSPMWESKSDWQQFKLLAKTVSEMAKKYMSGTVYDL
                     KSAPLGHNTQGEIAQPYGKIKDWKNGETEPIPGKTMPSLKLVTRDYTKIYDKFITLGPN
                     IVNNYGYKVDDQYDYLKGMNGTASEGIGAGCPLLDEDEKVCDAILRMSTASNGKLADRA
                     WEKKQERTGEHLTDIGRGHADDSMSFKQITAQPQEAYPTPIGTSAKHGGARYTPFSLMT
                     ERNIPTFTLTGRQHFYIDHEIFREFGENMATYKPSLPPVVMAPGDVDVPPVKDEVTLKY
                     MTPHGKWNIHTMYYDNLEMLTLFRGGPTIWISPQDADKIKVKDNDWIEVYNRNGVVTAR
                     AVVSVRMPEGSMYMYHAQDNEIYEPLSTITGNRGGSHNAPTQIHVKPTHMVGGYGQLSY
                     GWNYYGPTGNQRDLYANVRKLKKVNWSED"
     CDS             complement(6232..6483)
                     /locus_tag="ctg54_5"
                     /transl_table=11
                     /translation="MESIVQAHVLGMFMSSKELLLGNIKLQIIHHADLIFQDMNHGDVH
                     GELVSLGMNIVPFELSTHIFVVNYGSFGLLPRKNMKIP"
     CDS             6759..7778
                     /locus_tag="ctg54_6"
                     /transl_table=11
                     /translation="MNRYDRQERVHQIGVVGQQKISHATIMIVGVGALGSYTAEQLVRA
                     GVKRLVLIDPDTVDVTNLQRQSLFTEADANQQRLKVEAAKEHLHKINSACQIIAIPAPI
                     TADLIDEYQFTLCLDCLDNYQARDLLNKLAIIKNFDYLFASCAGTYGNVMAISPQNYPC
                     LNCLFPNINELKQNDCDLIGVNTALIPIVAGLQVSLALHYLVDKTQVNFNELITVDNWS
                     MQFSKFIINKNSHCPACTNPSSISLEEESAPELHMLCGENAYYTVKEKPINFGRLKEFL
                     AKKELLINANRLFLHFKWENRPVSIFKNGKIVMYDLPTSAIAQKQFESLNTLMKEDLL"
     CDS             7775..8272
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_7"
                     /sec_met_domain="MoCF_biosynth (E-value: 7.5e-34, bitscore:
                     107.4, seeds: 114, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKIAILTVSDSRTLDSDTSGKLIAMKMANAGLSVVDRVIVNDDI
                     VNIQTAYLQLEQQAIDIIITNGGTGVAQRDVTIPAIRPLLKRLIPGFGEAFRQISFDEI
                     GTRALASQALAGFNYRNQLTYCLPGSQNACQTALNKLILPEYEHLLFESSSQRKEVHHH
                     AH"
     CDS             8262..9479
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoCF_biosynth"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_C"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) MoeA_N"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg54_8"
                     /sec_met_domain="MoCF_biosynth (E-value: 4.5e-23, bitscore:
                     72.4, seeds: 114, tool: rule-based-clusters)"
                     /sec_met_domain="MoeA_C (E-value: 1.8e-13, bitscore: 41.5,
                     seeds: 41, tool: rule-based-clusters)"
                     /sec_met_domain="MoeA_N (E-value: 1.4e-39, bitscore: 126.2,
                     seeds: 1302, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLTRRTPISVAEAQKKINEIPLKTTTETIPLSEANHRILAEDVHA
                     HYDYPHFRRAGMDGYAILASDDHDFPREFNVRGEIQAGATWDQPLQPGDAVRIMTGAYV
                     PSDAGKVIRIEKTRPAEDKNKVQIITTESKTNITETGTDVKSGDIVLAKDQEINPGGLA
                     VLTAFGVQEVTVYKKPRIAIIATGTELLGPNETIEPGKIFNSNGIMLKNLVEETGGIVD
                     FETQLPDDANLIKQTLEEQIATHEIVITDGGVSVGDFDFIGDEARKADELLFNKIKQRP
                     GSVTTAFVQNNTLVMALSGNPGACFTGFYLYMEPLIRRYQHQASRIKRVRAILAAPYNK
                     TNGFDRYLRCTYEFKDDQFYVYPNGINRSGSLANLQTTTCLALIPHSTTPMKVGTETDA
                     WLLPFK"
     CDS             9458..9946
                     /locus_tag="ctg54_9"
                     /transl_table=11
                     /translation="MAITLQIIGHKKSGKTLITTALIERLSKEGYRVAALKHDAHNAAM
                     DVPTTDSARMSNAGANQVILQSPTEFFFHQKSNVPTLTEMVELLSDDNDFVLIEGHKEA
                     TQYPQILLLKPGEDPTNIAPTTPLKTGSIFSGTNADLLGKNTIVNWCYNYLKQIKENT"
     CDS             9946..10518
                     /locus_tag="ctg54_10"
                     /transl_table=11
                     /translation="MIGLVYAGGKSIRFGKDKATYHVPRLPATNVQLAVEKLMPLCQQI
                     IVCANETNRAHIIELVGQVPAVQIICDIPPYDHHGPLSAIIACTSQFSVVQDYLTLAVD
                     YPYITKDVLAILARTSNSYIVTSQHSHYSLAHFSISNEQVTTWVDNNSDWRLRSFITNK
                     CGCHPLAYRSSAEFSNLNYREVDLNEK"
     CDS             10508..10792
                     /locus_tag="ctg54_11"
                     /transl_table=11
                     /translation="MKSKDSMTNPDFQKLISLVLNDLTIRRTMLENREQEVNQQMSSLE
                     KDAELEQLDDQIQQIQADFDHYREFQDPEFDFSATKYFQGPSMGLPRHP"
     CDS             10943..11998
                     /locus_tag="ctg54_12"
                     /transl_table=11
                     /translation="VLETANWIQKYFNQSPDAIFLFKNDDLLVNNEPAQRLVTMLNLDV
                     NYLLQIGKNAWSQLENDDCASCLIKKRLKGAAVPITFHSNATHPFHFSMVYRPLDDKEN
                     VFALTLENSEQQQRLSQVEEQRILNQYVNEAHEKERQKISQDLHDSVAQGIYAAIMGIQ
                     RLATVQNPRNTEQFQSMSAAIEKQLQTTLKEIKELALDIRPSVLDNFGLIPAIKALAKR
                     LQNSTGITINVIALTSAEKLQKNIQNVLYRITQEAINNAIKHAHSTEITIIVTNHNSYL
                     QLEILDNGIGFDLEQHSRFNGHSLGLMNMNERVKAYNGAFTITSKINKGTTVKVKFPYN
                     NLNKDTVRTNV"
     CDS             11991..12644
                     /locus_tag="ctg54_13"
                     /transl_table=11
                     /translation="MYNVLVADDHAIVRSGISYLVDLQPNFTVVDGTASGTDTYIRVEQ
                     GGIDILIMDLSMPPGENGLITTRRIHDKFPKVKIIILSMHEEQEYINKAMANGAMSYIL
                     KSSPDSEIVNGLKHVINGEKYLDANIIVSKKDIKEINASGNILKLKGYNGLSKREKEVF
                     PLIALGYSNKEISQKMFISTKTVEAHKANISRKLHLHGRVELVQYAIHHHLIDL"
     CDS             12740..13012
                     /locus_tag="ctg54_14"
                     /transl_table=11
                     /translation="MATNLSQEDELRGILSDVARKRFTNSRQVNPVSNLFLTTKYAVEN
                     QYISGAVIDESFSSTLAEINLKNAVLTDRGRNKLAQLLTQSAKEN"
     CDS             13018..13986
                     /locus_tag="ctg54_15"
                     /transl_table=11
                     /translation="MDIQDKLKRDYENKSIYTAGFYADPDNDLANRKKLFDVLKSLVEN
                     QEATTPFALQIMLTNGEINVMPLGLVDLDELKKYENEQRSKHGLDEYNDDIPLLIQYAP
                     HAEKKEVVKKRIGTVQDLFTNFNEQIEKIWQTIKKFMQDNFALLTTIEKDLIADSQNVM
                     QEYRITFSKMTEAERKEKLGFSVPENEINQFCRYMADMHEVQAVVLSAGAFVNHELLGK
                     NSFTEMISDNIRRSTLFWVLDNTFYEIYYYFYMSNANDKLHKRLKHQRETFIVNMRNDA
                     FHRAQEFTEKQTKKVDFNEYFSDIFIPVAEQIIAEVNKFKD"
     CDS             13991..14896
                     /locus_tag="ctg54_16"
                     /transl_table=11
                     /translation="VNLTPDERLADALTTIIYQYPPMVREMINLNAGEKERLLRLSIFE
                     AFSHLSERDLTIDQITAAQLPELLALATHLNPPSFQPNNLTPGEFASQKAYSYVASYLM
                     NRFVHSLSTVGNPPQVLEELITDAGDVMLAQVRRLQFNYNQQFKVADYLADVKARWGLL
                     GAMTAKQSAVLSGAGNEIVSLAGQIGQAFGTASYITHEFQQLSNDPNLFIKMITAGQYP
                     LALLFARQQDPQWFNNFFSSNHRPSQEIFNQAYNLVLSRTDDVKQLITDIFSQLILDIE
                     VLPTGQTQDELLKLVEELKK"
ORIGIN
        1 tttttaagaa tcgattgtat tttttcgtaa aaaaataccc cctacatttt cgtaggaagt
       61 atttttagtc aaccatacca gttgacagat atcccagaat ttccctgtaa agaaatctga
      121 tgcttttatt atatcttctt atatactaat aaacccttgc acggcgccga tagacaataa
      181 aacgacggaa aatatattgc caaggtagcg ttaaagcatg aaccaaccgg gtgtatggga
      241 agtaaccaaa aattgctaat ccacagagaa cgtgaatttt ataaattaat ggcactgaac
      301 gcatcaattg ccattgagga ttaagaacaa ataggcttct tgcccatgga ctaattgttg
      361 ttcgatagtt gtaatcgata aatgcacccg taatagtaca tgctagacct agtgcaattg
      421 taatcagtaa agcccagtcg acaataatat cattgatatc acttgtctta taaacacgag
      481 aacaagtcat tcgtcgataa gtcagaattg caattcccac aaacgcaagg atccctgctg
      541 gaattcccat catcaatgac ccaaagatgt ggtacatatg ttcagtgatc ccaaaataag
      601 ctgtccaact tgctggaata aacattccta agcaatgacc aaagaaagct aaaataattc
      661 caatgtggaa agtaacgctt ccgatcatta gccatttctt ttcaaaaagt tcgcttgatt
      721 tggcagtaat tgagggatga aaatatttaa atctaacaaa tgttccaatg aaaaatgatg
      781 ccaacattat atatggataa ataacccata agaaaattga ccagccatta tgcatcttct
      841 cgcacctcca ttttaataca cgaaccaatt aatgaacgtg taagcctgat taactgaata
      901 tagggattat cactatctgt cactgcattt tttaaaaggg tataagttcc atcttcaatc
      961 acacttaatg ctaattggat atcctgacga cgcggatcat tagtataatc gccatatgct
     1021 agaaattcta acaatagagg caaataatca gaaagttcac tggtcgcttc tgatatacca
     1081 aacatctcat atagcatttt caaccgtgct aaaatggtcc ctcgttcacg ggaatcggtc
     1141 atcttatagt atgacatata aagagtataa cgtcggttca tttcaaaaag gtgagcgtac
     1201 atctcttgaa cttcgattga agatagtgcg gctaattcat caaaaaggct taataattct
     1261 ccccgtgttg ctgttgataa tgcgttatct gcaagtaata attgacgaat ctctggtgaa
     1321 aacgtttctg tatcaggata gtcaatcaag cgagaaagaa cggcaaatgt atcctttaaa
     1381 tctgtcaatc gtctgaaatc agtcacgcca aatccctcca tagaaactat cagcataaat
     1441 ctgattagtt gatttgccag cttctgcctt cttaaacata ctcttgtgtt ggggagctaa
     1501 tgcacagcct tcacattcat catagccaag actaccttgt tcggtttgtg catcttccat
     1561 ttctgccttt tggctacttg gaataacaaa acggtcttca tatttagcaa ttgccagtaa
     1621 acgataaagt gatgttgcct gttcttctgt taaatcaact cgttccagtt tactgctatc
     1681 aaaatcccga ccactagtct tagcacgcat gtatagccgc atcattgcaa gtttatataa
     1741 ggctttcttg atgacaggaa cgtttccagc agttaataga cttgccaagt attgaacagg
     1801 cacccgcatt tgatcaattc ctgggaagat catttcagga ttctttattg agtcccgtcc
     1861 ttcaaagtaa ctcataactg gtgatagcgg cggaatatac caaaccattg gcattgtccg
     1921 gtattctgga tgaagtggga aggcaatctt ttcttttact gccattttat agatcggtga
     1981 cttttgtgca gcttcaatca tctcttcaga aatgccatcc ttgagtgctt gcttgacaac
     2041 ttcaggatcg ttgggatcga ggaataagcc aagttgtgct tcatacagct tactctcatc
     2101 aggagttgat gctgcctctt ctactcgatc agcatcgtat agaatagcac caatatatcg
     2161 aattcgaccg acacaggttt cggcgcaaac tgttggttga ccttcttcaa ttcgcggata
     2221 acaaaaagta catttttcag ccttatgagt cttccagtta aagtagacct tcttatatgg
     2281 acatccagtc atgcaaaaac gccatccccg gcagcgttct tggtctacta aaacaatccc
     2341 atcttcatct cgtttgtaca ttgcgcctga tggacaagag gctacacaag gtgcattcaa
     2401 acagtgctca cataatcggg gaagatacat cataaatgcc tgctcaaagt tatttttgat
     2461 atccccttca attttttgca tgttaggatc ctgttggaca tattcagttg atcccgctaa
     2521 gtcatcatcc cagttaggac cagtggttaa ttccattcct tcgccagtaa tttgcgactt
     2581 aggacgagca acaggttgat gcttttgttc agggccaaat aacgtcttat aatcataggt
     2641 ccatggttcg tagtagttat ctaactctgg catatcatta ttgtaaaaaa tcttgccaag
     2701 agcgatttta tttaatttgc ttccagcacg taattttaat ttaccttttg aattaagggt
     2761 ccaccctcca tggtattgat cttcatcttc ccagcgtttt ggataaccga cacctggctt
     2821 agtttcaaca ttattaaacc acatgtattc agcgcctgga cgatttgtcc atgtattctt
     2881 acaagttact gaacaggtat gacaaccaat acacttatcg aggtttaaga ccatgctgat
     2941 ttgtgcttta atcttcactc cagttcacct tcttcagttt tcttacattt gcataaagat
     3001 cacgttggtt tccagttggt ccataataat tccaaccgta actcaattgg ccatatcctc
     3061 caaccatgtg tgttggctta acatggattt gcgttggtgc attatgtgat cccccacgat
     3121 taccggtaat ggtggaaaga ggttcataaa tttcattatc ttgggcgtgg tacatgtaca
     3181 ttgacccctc aggcatccga acagaaacaa ccgcccgcgc agtaacaacc ccattacggt
     3241 tataaacttc gatccagtcg ttatctttta ccttaatctt atcggcatct tggggactaa
     3301 tccaaatagt tggaccaccc cggaataatg tcaacatttc aaggttatcg tagtacatcg
     3361 tatgaatatt ccatttacca tgaggagtca tatatttaag tgtaacttca tcttttactg
     3421 gtggaacatc aacatctcct ggggccatta caactggtgg taaggatggt ttataagttg
     3481 ccatattttc accaaattca cggaaaattt catgatcaat gtagaaatgc tgacgacctg
     3541 taagagtaaa tgtaggaata tttcgctcag tcattaatga gaatggtgtg tatcgagccc
     3601 caccatgttt agcagaagtt ccgattggtg ttggataggc ttcttgtggt tgagcagtga
     3661 tttgcttaaa tgacattgaa tcatcagcat gaccacggcc aatatctgtt aaatgttcac
     3721 cagttcgctc ttgcttcttt tcccaggctc ggtcagcgag tttaccattg gaagcagttg
     3781 acatccgtaa gattgcatca catacttttt catcttcatc aagtaacgga cagcctgcac
     3841 caatgccttc gctggcagtt ccattcattc cttttaaata atcatattga tcatcgactt
     3901 tatagccata gttattcact atattaggtc caagggtaat gaatttatcg taaatcttgg
     3961 tgtaatcacg agtaaccaat ttcaaggaag gcattgtttt tcctggaatt ggttcagttt
     4021 caccattctt ccaatcttta attttcccgt acggttgagc aatttctccc tgggtattat
     4081 ggccaagtgg tgcactctta agatcgtaaa ctgttcctga catgtatttc tttgccattt
     4141 cagaaacagt ttttgctaag agcttgaatt gttgccagtc agactttgat tcccacatcg
     4201 gactgactgc tgcattaaat ggatgaataa atgggtgcat atcagttgat gaaaggtcct
     4261 tcttttcata ccaagtagca gctggcaaga caacatcaga gtacataggt gttgaaacca
     4321 tgcggaagtc catatcaaca acaagatcta acttaccaat tgctcccttg tcacgccaaa
     4381 ccatatcttg gggcttaact cgatcatttg gcttagcaag caatccgttt tcagcaccta
     4441 ataagtgttt cataaagtat tcagcacctt tgccagaaga tgcaaataag tttgaacgcc
     4501 ataggaagaa ggctttgggt tgattttggt tagcatcagg atcttcagca gcaaaatgca
     4561 aagtcccttt cttcaattca tcgacaactt tctttgaaat ttcatcaata tcagttgtat
     4621 tgtaatcttt tgcaaaagat agcggattac gatcaaattg tgggtatgat ggtaaccatc
     4681 ctaaacgaat tgccatttgg ttataatcag cattatgtaa gtaagagtgt ttactcttcc
     4741 aaacgggtga cttttgagct tgattatcaa tttcttcata acgccattga tcagttgcaa
     4801 agtaatacca agtagtacct tgcatttgac gggcaccacc tttttcccag tcattggcaa
     4861 aagtaatgtt tgcccaacct tcttgtggac ggagcttttc ttgaccaacg tagtgagccc
     4921 aaccaccgcc agtcatacca acacaaccgc acaacatcag catattaata atgtttcgat
     4981 agttcatatc ggcattgaac cagtggttga ctccaccacc catgattacc atacttcgac
     5041 cttcattttc ggccgcgttt tgggcaaatt cacgagcaat ttgaataact tgctctgctt
     5101 ttactcccgt acggctttct tgccaagcag gagtaaagta actctcagca tccattgcat
     5161 ctttagcagc aagttcatca ttaccagtcc gattaattcc catttgagcc atcattaagt
     5221 cgtaaacatt agtaaccaag tgttcttgac catctgtgaa tttgagcttt ttaactggta
     5281 aatgccgttg aacaacgctg tttccgtcat tactaaatgc agggaaatca gcaataattt
     5341 gttcagtttc ttcaccttga tcattaatag aaagtgccgg gtcaatctta ttgccatttt
     5401 ggtctaataa ttcaagattc catttttctt tagcattata ttcctgaccc atcgttccat
     5461 ttggaacaac aattttgtgg ttattttggt cataaaccac tgtcttccat gctggattaa
     5521 caatcgtatc atcatcaact aagtcactaa tccgaacaaa acgacctggt gtatagtgag
     5581 catcatttgc tgtacttggt tccaattcaa ccatgaatgg taaatcagta aatcgcttag
     5641 aataatcaat gaaacgtttg actgggtgct tttggtagaa ttcatctaaa attacataag
     5701 tcattgcttg agcaacagca gaatcactac ctggttctgg tgcaagccag tcatcagcga
     5761 attttacatt ttcagcataa tcagggctaa ctgctacaat ctttgttcct ttgtacctaa
     5821 cttctgtcat gaagtgtgca tctggtgtcc gagttaatgg aacgtttgat ccccacataa
     5881 taatatagga actgttatac cattctgcag attctggaac atcagtttgt tcaccccaaa
     5941 cttggggaga tgcaggcggt agatcagcat accaatcgta gaaactcatt tgttccccac
     6001 ccattaaggc gatgaatcgg gctccggcac tgaaactcat cattgacatt gcaggaattg
     6061 gggtaaaacc accaatacgg tcgggcccat atttcttaat tgtgtataag caagcagctg
     6121 aaatcatttc taatgcttca taacgatgaa cacgaattaa gccaccgtgt cctcggacct
     6181 ttttatactt tttagacttt tctggatctt cgacaatact tgcccacgca tctaagggat
     6241 tttcatgttc tttcttggca gcagtccaaa gctcccataa tttaccacga atatatgggt
     6301 acttaattcg aacgggacta tattcatacc aagagaaact agctccccgt ggacatcccc
     6361 gtggttcata tcctggaata ttaggtccgc atgatggata atctgtagct tgatgttccc
     6421 aagtaataat tccttgcttg acataaacat tccaagaaca tgagcctgta caattgactc
     6481 catgagttgt tcggacaact ttgtcatgcg cccatcgctg acgataaagc ttttcccaac
     6541 gacgactatt ttcttcaagt tgtgtaaagg ttccattaaa cttatcaacc ttgttaaaga
     6601 accgtgactt catcgttgat tgacctcctt tattgaatgg cttaccaata ttaaaaataa
     6661 agtaagtctt ttccctaatg taaagattag caccataact gctatactac gactagggaa
     6721 atacctatat tttcgaacta aatgaggtgt taatatccat gaatcgttac gatcgtcaag
     6781 aaagggtaca tcaaattggt gtcgttggtc agcaaaaaat tagccatgca actattatga
     6841 ttgtcggtgt aggagcattg ggaagttata cagctgagca acttgtccgt gctggagtta
     6901 aaagacttgt cttaattgat cctgacactg ttgatgtaac taatcttcaa cgtcaatcgc
     6961 ttttcaccga agcagatgct aaccaacaac ggcttaaggt cgaagcagct aaagaacatt
     7021 tacataaaat taattcagca tgtcaaatta ttgcgatccc agcgccaatt actgctgatc
     7081 ttattgacga atatcagttt accctttgtt tagactgtct tgataattat caagcacgcg
     7141 atctattaaa caaattggca atcatcaaaa attttgatta tctgtttgcc agctgtgcag
     7201 gaacctatgg gaacgtaatg gcgatttcgc cacaaaatta tccttgcttg aactgtcttt
     7261 ttcctaatat caatgaatta aaacaaaacg attgtgattt aattggggtt aatactgctt
     7321 taattcctat tgtagcggga ctacaggtat ctttagcgct tcattatcta gttgataaaa
     7381 cacaggttaa ttttaatgaa ttgatcactg ttgacaattg gtcaatgcaa tttagtaaat
     7441 ttatcattaa taaaaatagc cattgtccgg cttgcactaa tcctagcagc atttctttgg
     7501 aagaagaatc agcaccagaa ttacatatgt tatgtgggga aaatgcatat tatacagtca
     7561 aagagaaacc tattaatttt ggcagactta aagaattttt ggctaaaaaa gagctcttaa
     7621 ttaacgcaaa tcgattgttt cttcatttta aatgggaaaa tcgtccagta agtatattca
     7681 agaatggtaa gattgttatg tatgacttac ctacttcggc gattgcccag aaacagtttg
     7741 agtcattaaa tactttaatg aaagaagacc tattatgaaa aaaatcgcaa ttttaacggt
     7801 tagcgatagt cgaacattag atagcgatac ttctggaaaa ttaattgcta tgaagatggc
     7861 taatgcgggc ctatcagtag ttgatcgggt aatcgttaat gatgatattg tcaatattca
     7921 aactgcctac cttcaactag aacaacaagc cattgatatc atcattacta atggtggaac
     7981 aggagttgct cagcgtgatg ttactattcc ggctatccgt ccactcctca aacgcctaat
     8041 tcctggtttt ggggaagcgt ttcgccagat atcttttgat gaaattggta ctcgggccct
     8101 tgcatcacaa gccctagccg gatttaatta ccgcaaccag ctcacctatt gtttaccagg
     8161 ttcccagaat gcctgtcaaa cggctctaaa taaactaatt ttgccagaat atgaacattt
     8221 attatttgaa agcagttccc aacgaaagga agttcaccac catgctcact agaagaacac
     8281 caatctctgt tgccgaggca cagaaaaaga ttaacgaaat ccccctgaaa acaactacag
     8341 aaacaattcc cctatcagaa gctaaccatc gtattttagc tgaggatgtc catgctcatt
     8401 atgactatcc tcattttcgc cgagcaggaa tggatgggta tgcaatttta gccagcgatg
     8461 atcatgactt cccccgcgag tttaatgtcc gaggagagat tcaagctgga gcaacttggg
     8521 atcaaccatt acagccaggg gatgcagttc ggataatgac tggtgcatat gtcccttctg
     8581 atgcggggaa agtaattcga attgaaaaaa ctcgtcctgc tgaagataaa aataaggttc
     8641 aaattattac aactgagagt aaaactaaca ttacagaaac tggtactgat gtaaaaagcg
     8701 gtgatatcgt tttagcaaaa gatcaggaaa taaatcccgg tggcctagca gtcttaacgg
     8761 cttttggtgt tcaagaagta acagtttata aaaaaccacg gattgcaatt atcgccactg
     8821 gaactgaatt attaggccct aatgagacaa ttgaaccggg aaagatcttt aatagtaatg
     8881 gaattatgtt aaaaaatctg gtagaagaaa ctggtgggat tgttgatttt gaaacccaat
     8941 taccagatga tgctaatctt atcaagcaga ctcttgaaga acaaatagca actcatgaaa
     9001 ttgtaattac tgatggtggc gtttctgtcg gtgattttga tttcattgga gatgaagcac
     9061 gtaaagctga tgaattgctg tttaataaga ttaagcaacg accaggaagc gttacgactg
     9121 cctttgttca aaataatacg ttagtaatgg ctctttctgg aaatccaggc gcttgtttta
     9181 ctggctttta tctctacatg gaaccgctga ttcgacgtta tcaacaccaa gcaagccgaa
     9241 ttaagcgagt acgggcaata ttagcagccc catataataa aactaacggc tttgatcgtt
     9301 accttcgttg tacttatgaa ttcaaagatg atcaatttta tgtttatcca aatggaatca
     9361 accgatctgg ctcattagct aacctccaga cgacgacctg tttggcactg attccgcata
     9421 gtacaactcc aatgaaggtt ggaacggaga ctgacgcatg gctattaccc ttcaaataat
     9481 tggtcataag aaaagcggga agactcttat cacgacggct ttaattgaaa ggctttcaaa
     9541 agaaggatat cgagtagctg ctcttaaaca tgatgcccat aatgctgcaa tggatgtgcc
     9601 aactactgac agtgctagaa tgagtaacgc tggagcaaac caagttatct tgcaatctcc
     9661 aactgaattt ttctttcatc aaaaaagtaa tgttccaact ttaacggaaa tggttgagtt
     9721 gttaagtgac gacaatgatt ttgtcttgat tgaaggccat aaggaagcca ctcaatatcc
     9781 gcaaatttta ttattaaagc ctggcgaaga tcctactaat attgctccta ctacgccgct
     9841 taaaaccggt agtattttta gtgggacaaa tgctgactta ctagggaaaa atacaattgt
     9901 aaactggtgc tataactact taaaacaaat aaaggagaat acttgatgat tggattagta
     9961 tacgcgggcg gcaaatctat tcgctttggt aaagacaagg ccacttatca tgttccaaga
    10021 ttaccagcta ccaatgtaca gctagcagtt gagaaactaa tgcccctttg tcagcagatc
    10081 attgtttgtg ctaatgaaac aaatcgtgca catataatag aattagttgg tcaggtaccg
    10141 gctgtgcaga ttatctgtga tattcctcct tatgatcatc atggtcccct ttcagcaatt
    10201 attgcttgta ctagtcaatt ttctgttgtt caagactatt taactttggc tgttgattat
    10261 ccatatatca caaaagatgt acttgccatt cttgctcgta catccaactc ttatattgta
    10321 acaagtcagc atagtcatta ttcattagct catttttcaa ttagcaatga acaagttact
    10381 acatgggttg ataataatag tgactggcga ttacgtagtt tcatcactaa taaatgcggg
    10441 tgtcatcccc ttgcatatcg ctcaagtgcc gaattttcaa atttaaacta tcgtgaggtc
    10501 gatttaaatg aaaagtaaag attcaatgac aaatcctgat tttcaaaaac tcatttccct
    10561 tgtcttaaat gacttaacaa tcagacgaac aatgttagaa aatcgggaac aagaagtaaa
    10621 ccaacaaatg agttcactgg aaaaagatgc tgaattggag caattggatg accaaattca
    10681 acaaattcaa gctgattttg atcattaccg tgaattccaa gatccggaat ttgattttag
    10741 tgcaaccaag tatttccagg gaccatcgat ggggttacca cgacatcctt aaaagctaga
    10801 tggcagggct aaagaagcag agcttttctt agccctgcct tttaagttgt ctatcgttgc
    10861 ttctagccaa agaaagcgtt aatatataaa ataggaatat tatgatagca attggggaat
    10921 tttattgggg aggaagcaga tcgtgcttga aacagctaat tggatacaaa aatattttaa
    10981 tcaatcacca gatgcaatct tcttatttaa aaatgatgat cttttagtta ataatgagcc
    11041 ggcacaacgg ttagttacta tgcttaattt agatgtcaat tacctattac aaattggaaa
    11101 gaacgcttgg tcacaactgg aaaatgatga ctgtgcgtca tgtctgatta aaaagcggtt
    11161 aaaaggagct gcagttccga taacatttca ttccaatgct actcatcctt ttcacttttc
    11221 aatggtttat cgtcctcttg atgataaaga aaatgtcttt gccctaactc ttgaaaatag
    11281 tgagcaacag cagcgccttt ctcaagttga ggagcaacga attctcaatc aatatgtcaa
    11341 tgaagcgcat gaaaaggaac ggcaaaaaat ctcacaagat cttcacgata gtgttgcgca
    11401 gggaatctac gcggcaataa tgggcattca aagattagca acggttcaaa atccaagaaa
    11461 cactgagcag tttcaatcaa tgagtgctgc aatcgaaaag cagttacaaa cgacccttaa
    11521 agagattaaa gagctcgcac tcgatatccg cccctcggtg ctcgataatt ttggcttaat
    11581 tccagcaatc aaagctttgg caaaacggct tcaaaatagt acaggaatca cgattaatgt
    11641 tatagccctt acctctgccg aaaaactgca aaaaaatatc caaaacgttc tttaccgaat
    11701 tacacaagag gcaattaata acgcaattaa gcatgctcat tcaacagaaa taactattat
    11761 tgttaccaac cataatagtt accttcagtt agagatcctt gataatggta tcggctttga
    11821 tcttgaacag catagcagat ttaatgggca ttcacttgga ttaatgaata tgaatgaacg
    11881 cgttaaggca tataatgggg cctttacaat tacatcaaaa attaataagg gaacgacagt
    11941 caaggtgaag tttccctata ataatttaaa taaggatacg gtgagaacaa atgtataacg
    12001 ttttagttgc agacgaccac gcaatcgttc gttcaggaat ttcatattta gtcgatcttc
    12061 aaccgaattt tacggtggtt gatgggacag cgagtggaac agatacatat attcgagttg
    12121 aacaaggtgg aattgacatt ttaattatgg atttaagtat gccccctggc gaaaatggtc
    12181 tgattacgac tcggcgaatc catgacaagt ttccaaaagt taaaattatc attctctcga
    12241 tgcacgaaga acaggagtat atcaataagg caatggcaaa tggcgcaatg tcttatattt
    12301 tgaagagttc accggatagc gaaattgtta acggccttaa acatgttata aatggtgaaa
    12361 aataccttga tgcaaacatc attgttagta agaaagacat taaggaaata aatgcttctg
    12421 gtaatatctt aaagttaaag ggctataatg gtctctctaa aagagaaaaa gaagtctttc
    12481 cacttattgc tttagggtat tcaaataaag aaatctccca aaagatgttt atttcaacaa
    12541 agacagtaga agcacataaa gcaaatattt cacgcaaact tcatttacat ggacgggttg
    12601 aactagtaca atatgctatt catcaccatt taattgacct ttaactagcg gggattctga
    12661 attaagaaga atccccgatt ttatttactt cgatattttt ttacaataaa agaaatacga
    12721 ttaaaggagt ggatttataa tggcgacgaa cctcagtcaa gaggatgagt tacggggaat
    12781 cctcagtgat gttgctcgca aacgctttac taatagtcga caagttaatc ccgtttccaa
    12841 cctgttttta acaactaaat atgcagttga aaaccaatat atttctggag cagttattga
    12901 cgaatcattt agttcaacat tagcagagat aaatttaaaa aatgctgttt taactgatcg
    12961 cggtcgtaat aagcttgcac aacttctcac ccaatcagca aaggagaatt aattaagatg
    13021 gatattcaag ataagctaaa acgagattac gaaaataaat cgatctatac tgcaggcttt
    13081 tacgcagacc cagataatga ccttgcaaat cgtaaaaaat tatttgatgt cttaaaatcg
    13141 ctagttgaga atcaagaagc cacaacgcca tttgctttac aaatcatgct tacaaatggc
    13201 gaaattaatg taatgcccct cggcctcgtt gatcttgatg aacttaaaaa atatgaaaat
    13261 gaacaacgat ccaagcatgg tttagatgaa tataacgatg atattcctct tctaatccaa
    13321 tatgcccctc atgcagagaa aaaagaagtg gttaaaaaaa gaataggtac agttcaagat
    13381 ctttttacaa actttaacga gcaaattgaa aaaatatggc aaactattaa gaaatttatg
    13441 caggataatt ttgctttatt aacgactatc gaaaaggatt tgattgctga tagtcaaaat
    13501 gtgatgcaag aatatcggat tactttttcc aagatgactg aggctgaacg aaaagaaaag
    13561 ctggggttta gtgttccgga aaatgaaatc aaccaatttt gccgttacat ggctgatatg
    13621 catgaagtac aagcagtcgt attatctgct ggtgctttcg ttaaccatga acttcttggt
    13681 aaaaattcct ttactgagat gataagcgat aacattcgac ggagcaccct cttctgggtt
    13741 cttgataata ccttctacga aatttactac tacttctaca tgagcaatgc caatgataag
    13801 cttcataaaa gacttaaaca tcaacgagaa acctttatcg ttaatatgcg taatgatgct
    13861 tttcaccgtg cacaagaatt tactgaaaag caaacaaaaa aggttgattt taatgaatac
    13921 ttcagtgata tcttcatccc cgttgctgaa caaataattg ctgaagtaaa taaatttaag
    13981 gactgatact gtgaatttaa caccagatga acggctggca gatgcattaa caaccattat
    14041 ttatcaatat cctccaatgg ttcgtgaaat gattaatctt aatgccggtg aaaaagaacg
    14101 tctgctaaga ttatcgattt ttgaagcttt cagtcacctc agcgaaagag atcttacgat
    14161 tgatcaaatc acagctgctc aattaccgga actattggca ttagcaactc atttgaatcc
    14221 tccttctttt caaccaaata acctaactcc tggggaattc gctagtcaaa aggcatattc
    14281 atatgttgcg agctatttga tgaatcgctt tgtccattcg ttaagtactg taggtaatcc
    14341 cccacaggta cttgaagagt tgataactga cgctggggat gtgatgcttg cacaggttcg
    14401 acgactgcag tttaactata atcagcaatt taaggtagct gattatttag cagatgttaa
    14461 agcacggtgg ggattacttg gagcaatgac cgcaaaacaa agtgccgtcc ttagtggagc
    14521 aggaaatgaa attgtctcgc ttgcaggaca gattggtcaa gcctttggta ctgctagtta
    14581 tattacacat gagtttcaac agcttagcaa tgatcccaac ttgtttataa agatgataac
    14641 ggctgggcag tatccactgg cacttttatt cgctcgtcaa caagatccac aatggtttaa
    14701 taattttttc tcttcaaatc atcgtccttc acaagagata tttaaccaag cttataactt
    14761 agtgcttagc cgcactgatg atgtcaaaca gctgatcacc gatatcttct cccagttaat
    14821 ccttgatatt gaagtattac cgactggtca aactcaggat gaattgctta aactagttga
    14881 agaattaaaa aaataattta aaactaaaaa tggagattaa ggaagaaatt atcctcatct
    14941 ccatttttta atgtgcttat ttaacgatat gaacgtcacc atgaatataa tgtttccata
    15001 gagcaaacca gcaaattgca ctggttagcg ctaaaagcgc aattccaagc tcataactac
    15061 ctgtccattg gtaaatataa ccaataatta gtggtgggaa gaatccccca aggccaccaa
    15121 cagctccaac aaaaccagta actgctcctg tattaccttg ggatacatac ggaaccattt
    15181 taaagacaac cccgttacct attccggcag aaagaccaac caaaacaatt cctgcgataa
    15241 acatgaattg attgtggaaa ctaagcataa tccaaatagc aaagataacg attgctacaa
    15301 agacccattg taataatgcc atcggtcgtt tcctatcggc aaggtaacca ccaaatggcc
    15361 gaactaacgt acatacaaag gcaaataagg ccgaataaag acctgctgta acaggagtat
    15421 aatggaacat cccagttaag aatgtcggcg ttaaatttgt aaaggcaacg aataaaccga
    15481 atgtaaggaa atagaacagt gataggtacc atgttccact gtctgtggca acagataatg
    15541 ctccctttat cgtcttgctt ttatcaactg gcatttcctt acaaaaaact gcaaagagaa
    15601 caccaaagat cactgtaaga ataatcaaga agtaataaac actatcaaat cccgccgcct
    15661 tagaaatata cggtaaagtc attgcagcta cagcattccc catgtttccc attgagacaa
    15721 tcccaagagc tagtccctgc tgttctggcg ggaaccaaac tgaagcataa gaaactccaa
    15781 cagcaaatga tgttcctgac atcccaacga gcaatgcagc aaagagcaac atcccgaatg
    15841 aatggacatg tggaatcata attagtggaa tcaaaataaa agccatcaaa atcaaataga
    15901 cctttttccc accataacga tcacttaaga tccccactgg aattcgcata attgacccca
    15961 aaaggacagg cgttgctaat aataacgttc gctgcgatac atcc
//
