LOCUS       gnlProkkaGMDKHDHI_9    14442 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|GMDKHDHI_9.
ACCESSION   gnlProkkaGMDKHDHI_9
VERSION     gnlProkkaGMDKHDHI_9
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##antiSMASH-Data-START##
            Version      :: 7.1.0
            Run date     :: 2025-04-28 14:39:16
            Original ID  :: gnl|Prokka|GMDKHDHI_9
            NOTE: This is a single region extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 14442
            ##antiSMASH-Data-END##
FEATURES             Location/Qualifiers
     CDS             complement(1..798)
                     /locus_tag="ctg8_1"
                     /transl_table=11
                     /translation="MSIPIQIFAATISILFDYIFFFLLIKIRPTKYDICPLLIIFIIVF
                     FINGLGYIGSYLVPFFEGSFLYLNYKRRASNKKLLGALLITFITSILIAFLAFVIGKLF
                     LLSTNQRLGINLIFSITILIFFFYYNPIKKIQEGNETLNLWILFYLLVSLIIVGFITFT
                     TTEVTPAFIVIFCLLVLQCSFTVFIYRISKQIQQKKLQLQEKKDLLFLIQNLEENQSKL
                     RRFKHDYQNLLNSLKLSAIHGDNQALLDKLENYSRDNLGKDSLW"
     protocluster    1..14442
                     /aStool="rule-based-clusters"
                     /category="RiPP"
                     /contig_edge="True"
                     /core_location="[1837:13468]"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
                     /tool="antismash"
     proto_core      1838..13468
                     /aStool="rule-based-clusters"
                     /tool="antismash"
                     /cutoff="20000"
                     /detection_rule="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /neighbourhood="5000"
                     /product="RiPP-like"
                     /protocluster_number="1"
     cand_cluster    1..14442
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(strepbact or Antimicrobial14 or
                     Bacteriocin_IId or BacteriocIIc_cy or Bacteriocin_II or
                     Bacteriocin_IIi or Lactococcin or Antimicrobial17 or
                     Lactococcin_972 or Bacteriocin_IIc or LcnG-beta or Cloacin
                     or Linocin_M18 or TIGR03651 or TIGR03693 or TIGR03601 or
                     TIGR03795 or TIGR03975 or DUF692 or TIGR01193 or (YcaO or
                     TIGR03604))"
                     /kind="single"
                     /product="RiPP-like"
                     /protoclusters="1"
                     /tool="antismash"
     region          1..14442
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="RiPP-like"
                     /region_number="1"
                     /rules="(strepbact or Antimicrobial14 or Bacteriocin_IId or
                     BacteriocIIc_cy or Bacteriocin_II or Bacteriocin_IIi or
                     Lactococcin or Antimicrobial17 or Lactococcin_972 or
                     Bacteriocin_IIc or LcnG-beta or Cloacin or Linocin_M18 or
                     TIGR03651 or TIGR03693 or TIGR03601 or TIGR03795 or
                     TIGR03975 or DUF692 or TIGR01193 or (YcaO or TIGR03604))"
                     /tool="antismash"
     CDS             complement(818..937)
                     /locus_tag="ctg8_2"
                     /transl_table=11
                     /translation="MKKLSTQQLSLIKGGAIPGINYTDHSSYASWMLKKLIKH"
     CDS             complement(1153..1635)
                     /locus_tag="ctg8_3"
                     /transl_table=11
                     /translation="MNKLFQWFYNMPKLTNQGNKDYMAKISLNIAVSLFLFNLVAVLIS
                     FFIVTTTENYELSFNILAGALLIFTVYIVGGYSICAKRKINRVVTHDNTHIVKNSFAST
                     VYITLIIYLLNSLTNALSFHTSLISELKNPMSYIIPTVIGIIYGTLMAIITWYRGK"
     CDS             1838..2044
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_4"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 5.5e-17,
                     bitscore: 52.3, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLDNSQLKMILGGKNSWQQNVWGVARSTAAGAGLGAAICGPGC
                     AFVGAHYGAIVWAGTTGATHGFH"
     CDS             2071..2259
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: Bacteriocin_IIc"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_5"
                     /sec_met_domain="Bacteriocin_IIc (E-value: 7.3e-11,
                     bitscore: 32.6, seeds: 35, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKQLKYNQLELIIGGNRWGNATIGAMNGAKYGVKLCRPGGPWAMG
                     GCGLVGAGIGGYVGYRF"
     CDS             2612..2920
                     /locus_tag="ctg8_6"
                     /transl_table=11
                     /translation="MILINFLKKNKWNIIAILIFFIICVYYAYNKNIVASTSSLLCAIL
                     WLIDCLKKQYFFLEGIAIILYAIFILIIRIDLWPGALACIVIGLFILFFYLKKLKKQ"
     CDS             complement(3256..3963)
                     /locus_tag="ctg8_7"
                     /transl_table=11
                     /translation="MTYFVSILIAKLLFHKVKDQNIRQIATYGSIYSNNGFMGVPLAQG
                     LFESVGVFYAVASMIGFNVMSWTQGIGIFQKRQPHDWRTQLKKIILNPNIIAIIIGLFL
                     FISSFRLPKLIAGFIDYTSPAFTPLSMIVIGSNLANLSIKNIKLPTALWGSLFVRNIFF
                     PILGTTILLLLGITGVPLFTTVILSACPVAGLVVLFTLQSNGDARPATVLMSISTILSL
                     VTIPLVYWFASLW"
     CDS             4464..5144
                     /gene_functions="regulatory (smcogs) SMCOG1008:response
                     regulator (Score: 212.9; E-value: 6.9e-65)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg8_8"
                     /transl_table=11
                     /translation="MNKAVIMLVEDEESLASFLITELELEGYEVIWAKDGREALEIFKE
                     KEITLILLDWMLPIYDGLTVLRRIRQSSNVPIIMITARSQTSDISMALDQGLDDYITKP
                     FEIEELLARIRVVLRRLGQKKAEKYDYKFRPFEINLLKHQFMVDGKRVHLTPKEFSLMV
                     ALIKEPGVVQTRDDLLNEIWGYDFDGQTNTVDVYIRALRNKLGKYRDLIKTVRGIGYVL
                     GDEQ"
     CDS             5141..6472
                     /gene_functions="regulatory (smcogs) SMCOG1003:sensor
                     histidine kinase (Score: 181.2; E-value: 7.3e-55)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg8_9"
                     /transl_table=11
                     /translation="MSNTHPVTASRQLTRLFLMLFTVILVVINLLFVVTATNLIYRYAD
                     DQAEEVIETIEEDWPENQNRETFLNAYVARQDDDAIEITDGKREYTSPKAHKIFKRIDQ
                     RNLAIKNLQLTRHGVYYLRQQKIDHNRIVKVAINVDDLIKLTGWLLIVTLLINLAISII
                     ALPIIHRLARRWTRPLTNLDNEIDAITPQSNRLQTLTVPQQPLEVRKVAQSFNHLLGRQ
                     YRTMQREKEFIANASHELKTPLAGILGHVNLIRRHGDKHPELIGKSLKYIDQEAQRMSQ
                     LINELLILEGHQTKKLTEINLSKIIFAEVESLQGAYQQKFITDLNPNISYRITKGDFQS
                     LVHNLLENAAKYSPTDSIIDVLLTTDDRHIILRVADQGRGIAKENREKVFERFYREDES
                     HSNKIAGSGIGLAIVKMIIEKYHGKITIRDNEPSGTIFTVYLPK"
     CDS             6577..7227
                     /locus_tag="ctg8_10"
                     /transl_table=11
                     /translation="MTEKIEKRQDQQPKPDKKKARKFPKMTKKVLITACVCGGLVLGAG
                     GIAGVAAMDGYHAQIEAAVKHEKLANKSDIKINQQAAIDQFNKKYPDKHLNEVELESDK
                     GKYVYKVKGFDNTNEYKVKANAKDGKLISNKSEKLDQNEKEYTLDPGKAISRDEASQIA
                     EKAAKKGSAIEWKLEQEKENQAVWEVKVKDGRTVKEVKIDAGSKKVLAVENNH"
     CDS             7349..7540
                     /locus_tag="ctg8_11"
                     /transl_table=11
                     /translation="MLKKHPLALYITWIVALAVIPLPLIILTNSQLTADYEDLFAYDVG
                     ILAYVWWLVIIFLSTRPR"
     CDS             7568..8641
                     /locus_tag="ctg8_12"
                     /transl_table=11
                     /translation="MYFLHASLGVAALVAATAHKFLSPGADHLVETTGDIAWYLAIVGI
                     IYAIVFMSGWLVDRFKLLRQIKLKLSIICSHQVSVWIHRLNLLLILLIWLHVHLIDDFS
                     EMTSFITTFDAYTYIIIGYYLLAKFITLFKTNGTVIANKQLAPNTQQLVIKLDKNDPAY
                     QAGDFYFVSFRGSKSIGREKHPFSVTSAPKNNPHEIAFTIQKLGDFTKKIPSVQIGTRV
                     YLEGPYGQFDRIIRKLSKDQPLVFYGLGSGLAPLLSLAEQYGNQRQIKILWSSSKKNGL
                     YFEKALEKLKKNPNITVIAKEGRFTEESIKKELSPKEIDQGLYFIVGPAHVILNVEKML
                     RKLNVKSPHIIDERLTM"
     CDS             complement(8981..9118)
                     /locus_tag="ctg8_13"
                     /transl_table=11
                     /translation="MSKETALITGTTGGLGMEFVKIHAQKGGNLVLVGRNPQKACPARV
                     "
     CDS             complement(9436..9705)
                     /locus_tag="ctg8_14"
                     /transl_table=11
                     /translation="MAKKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREKELSLRDRSL
                     LTVTALITKGAFEQLPYHMQTAKNNSITKDEIAEIITQLAFYVG"
     CDS             complement(9988..10326)
                     /gene_functions="other (smcogs) SMCOG1026:transposase
                     (Score: 63.8; E-value: 2.6e-19)"
                     /gene_kind="other"
                     /locus_tag="ctg8_15"
                     /transl_table=11
                     /translation="MFKQAQASEGKVASLIHTDRGAAYTSRAFNQYLAINGASHSYSAP
                     RTPADNAVIEYWWADFKAIWIAHMPKAQTLVELEQQVRDGINYFTHKFISGTRNDLTAA
                     EFRFGKAN"
     CDS             complement(11112..11228)
                     /locus_tag="ctg8_16"
                     /transl_table=11
                     /translation="MINFIYQLVSKHLTNRFTIIWLIPIVSVSGTWLLKYFH"
     CDS             complement(11309..13468)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     RiPP-like: TIGR01193"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) Peptidase_C39"
                     /gene_functions="transport (smcogs) SMCOG1288:ABC
                     transporter related protein (Score: 296.2; E-value:
                     8.5e-90)"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg8_17"
                     /sec_met_domain="Peptidase_C39 (E-value: 7.6e-42, bitscore:
                     132.6, seeds: 36, tool: rule-based-clusters)"
                     /sec_met_domain="TIGR01193 (E-value: 1.4e-289, bitscore:
                     952.6, seeds: 5, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MYNAFNKYYVSQVDEADCGVAALSMILRKFGSKVSLATLRKATKT
                     TTEGTTALGIVEAAKKYKLNVAAYQADINLFSSNEASYPFIAHLIKKDTGLLHYCVVVK
                     NAKNHLIIADPNPNIKVQKVSKEAFFQEWTGIAIFANPANDYEIIQEQSPTLKRLIIPV
                     IEQKKLLIGIVTSAFLVTFINIISSYFFQGLIDRLIPYKLLTPLNIICIGLLIAYVANS
                     LFNFTRDYLLATLGQRLSKTILLDYIKHVLKLPMEFFSTRKTGDIVSRFTDANKVIDAL
                     VNSIISIFLDTTMLCIIGITLAIQNLKLFILTLITIPVYLVIIGSFTHSFKVLNQKEME
                     SNATVSASIIEDIRGIETIKSLNSEENRLTKIENEFNDFLHKSLTHTKLNSIQQSLKSF
                     TQLAFSLIILWFGAIQVINNQFTIGQLMTYNALLVYFITPLQNIINLQPKIQSAQVANN
                     RLNEVYMVQDEFIKKKLSHKITNGDIEIKNVNYSYQYNHPILKDINWKITPGTKMTVVG
                     MSGSGKSTLMKLLVNYFNPTSGQILVNGLNILDIDKTTVRSFINYIPQNPYIFSGTIKE
                     NLLLGSRTDITDEDITKACKVAMIHDDIMHLSLGYDSKLDENATTLSGGQKQRLTVARA
                     LLSPAKVIILDESTSGLDIITEEKLVKNLMNLTSKTIIFIAHRLSIAKITNNITVIDNG
                     TIVEQGTHNQLLKEHGLYFNLLQKY"
     CDS             complement(13486..14253)
                     /locus_tag="ctg8_18"
                     /transl_table=11
                     /translation="MDYHLLVCDDDQLQAKNIATLLKMSSIILEEDDIHPNVDLIATDA
                     ASILDYLESNPDLTNIVAFLDIQLDENKQSQAGLALAQQIQKKHRNAQIIFITTHEELA
                     FLTFQRRINPLDYIVKTTDQRKLQRRLTETLELAIRHLNQFYIQTHTFKYKIGTRIINV
                     NFNNILYITTTKFPHKLKIVTINGQGEFSGNIKDVEQNYSFFFKASQSALINPQNIESI
                     NTKSRIVTFINGDKIKFSRSRTKELNKIYKEKL"
ORIGIN
        1 ccaaagagaa tctttaccaa ggttatctcg agaatagttt tctaatttat cgagtaaggc
       61 ttgattatca ccatggatgg cacttaattt gaggctattt agtaagtttt gataatcatg
      121 tttaaatcgt cttaacttcg attgattttc ttctaggttt tgaatgagga ataataagtc
      181 tttcttttct tgaagctgga gctttttttg ctgaatttgt ttactaattc gatatataaa
      241 gactgtaaaa ctgcattgaa gaactagtaa gcaaaagata acaataaagg ctggcgttac
      301 ttccgttgtt gtgaaagtta taaagcctac aatgattagg ctgacaagaa ggtaaaataa
      361 aatccataaa ttaagagttt cattaccttc ctgaattttt ttaattggat tgtagtagaa
      421 aaagaaaatt aaaatggtta ttgagaatat taaattgatt ccaagacgtt gattagttga
      481 tagaaggaat aatttaccga taacaaatgc taaaaaagca atcaatatag atgtgataaa
      541 agttattaaa agagcaccta gcaatttttt gttggatgcc cttcgtttgt aatttaaata
      601 tagaaaactg ccctcaaaga atggtactaa atacgatcca atatagccta gtccgttaat
      661 aaagaacaca ataataaata ttatgagcaa ggggcagata tcatattttg tcggtcttat
      721 ttttataagt aggaaaaaga aaatataatc aaacagtatt gatattgttg cagcaaaaat
      781 ttgaattgga atagacaatg tataacctct tataagatta gtgctttatt aatttcttaa
      841 gcatccaact ggcataacta ctatggtcag tataattaat accgggtata gcaccacctt
      901 taattaaaga tagttgctga gttgatagtt ttttcataaa taaatctctc ctattgtttt
      961 atcagtaatt tattttaaca ggatgcatca aaaaaatcat aaataatcaa aagtagttgt
     1021 ttaaggttca aatcctgtaa gaaatgagtc cgattattct gttagtaaaa aataataaat
     1081 gttaaatttt tgtttaactt ctcaataagg aaattgcttt cagttaatct tccttaatta
     1141 aaaacatact tattatttgc ccctatacca tgtaataata gccataagcg tcccatatat
     1201 aatcccaatt acagttggga ttatataact catgggattt tttaattcgc taatgagtga
     1261 agtatgaaaa ctaagagcat ttgtaagaga attaagtaaa taaataatca gtgttatata
     1321 tacagttgag gcaaaactat tctttacaat atgtgtgtta tcgtgagtca cgactctatt
     1381 aattttacgt tttgcacata tagaatagcc accaacaata taaacagtaa aaatcagtaa
     1441 cgccccagct aaaatattaa aagacaattc ataattctct gttgtagtaa caatgaaaaa
     1501 ggaaataagg acagcaacga ggttaaaaag aaataagcta acagcgatat taagactaat
     1561 cttcgccata taatctttat taccttgatt tgttaatttg ggcatattat agaaccattg
     1621 aaaaagttta ttcattaatt tattcctttt aaaaagtttg gtttttacca tagcataatt
     1681 tatctttttt aataattttc ttctaatttt agtggaattt tagcatatta ggatgttgaa
     1741 gcaggatatg agtgtaattt gtacaaatta gaagtttcca tttagcagtc ttaatttact
     1801 ttatgcttaa agtatagaaa ttaaggaggt aattgttatg aaaaaattag ataattcaca
     1861 attaaaaatg attttaggtg gtaaaaattc ctggcaacaa aacgtctggg gagttgcgcg
     1921 ttctacagca gcaggtgcag ggcttggtgc agctatctgt ggcccaggtt gtgcatttgt
     1981 tggggcacat tatggtgcta ttgtttgggc agggactact ggtgctaccc atggctttca
     2041 ctaaaaatta agaatacgag gagaattgta atgaaacaat taaaatacaa ccaattagaa
     2101 cttattatcg gcgggaatcg ttggggaaat gcaacaatcg gcgcaatgaa tggtgccaaa
     2161 tatggagtga aactttgccg tcctggtggt ccatgggcca tgggaggatg tggtcttgtt
     2221 ggtgctggca tcggcggcta tgttggatat cgtttctaaa ataggaggaa ttctttataa
     2281 aaaaattttt gtttgatcca ttatattttt ttgctgtagc ttttatgtat ttaatatttg
     2341 attacaattt tggcatgata tcgatgtcaa tcttttgtgg actttcatta ttaattagta
     2401 atctaggaaa gaaattttta tatttgcaag cactattgtt cataatatat ggattattac
     2461 tttttatagt tcatccaagc acatggatag tttctgtaat tttgatctta attggaatag
     2521 tcttctttat attttatttt agaggatgaa ctggctttta gaatagttag agtcggagga
     2581 aaaattgttt cgactatcat gtggagtttt aatgattttg attaattttt tgaaaaagaa
     2641 taagtggaat ataattgcaa tattaatatt tttcattatt tgtgtatact atgcatacaa
     2701 taagaatatt gttgcttcta catcttcttt actttgtgca atcttatggc tgattgattg
     2761 tttaaagaaa caatattttt tcttagaagg aatagcaata atcttatatg ctatatttat
     2821 tttgatcatt cgaatagatt tatggccagg tgcattggcg tgtatagtaa taggattgtt
     2881 tatcttattt ttctatctaa agaaacttaa aaagcaataa tctagagaat aaaaggtatg
     2941 atcccagttg gatattggaa tcataccttt ttatcttgca cttcaacttt ataaatttca
     3001 ttacgcaaga ctcttcgtta ctttagttta aatattcaaa gtatatgcga gagttcttgc
     3061 gttttcttgt ttttaaagca caaacgcata ggatcacagt aatttaaccc gatcctatgc
     3121 atttaatttt caattgtaat atatggttta ttcatttata aagcctccac gtatctaatt
     3181 ccatcataga ttaaggaggc tattatttga aatgcttatt atatttaata ctttattcaa
     3241 agattgtata tatcattacc atagactagc aaaccaatag actaatggaa tagttactaa
     3301 actcaaaatg gttgaaatac tcattaagac ggttgctggc cgtgcatctc catttgattg
     3361 taaggtaaaa agaacgacta atcctgctac cggacatgca ctaagaatta ctgtggtgaa
     3421 gagtggaaca ccggtgattc ctaataataa taagatagtt gtccctagaa ttgggaagaa
     3481 aatattcctt acgaagaggc ttccccagag cgcagttggt aatttgatat ttttaatact
     3541 taggttggca agattgcttc cgatgacaat cattgatagt ggagtaaacg ctggactagt
     3601 gtaatcaata aaaccagcaa ttaattttgg caaccgaaaa gaactaatga ataggaaaag
     3661 gccaataata atagcgataa tattaggatt taaaataatt ttctttaact gtgttctcca
     3721 atcatgaggc tgccgttttt gaaaaattcc aattccctga gtccatgaca tgacattaaa
     3781 accaatcatt gaagcgacgg catagaagac acccacactt tcgaaaagtc cttgtgctaa
     3841 tggaacgccc ataaaaccat tgttagaata gatgcttcca taagttgcaa tttgacgaat
     3901 attttggtcc tttactttat gaaaaagtag ttttgcaatc aaaatggaaa caaaataggt
     3961 caaaaagaca ccaacaatta atagtaataa ttgataaaat cgtgatcgct aaaacggctg
     4021 ttcaaaggct ttaataatta cgattggcga taaaaagtag agtgtaatat ttgttaggtc
     4081 attaattgat tgcggatgga gaaatccaag ttttctaata actgccccta aaagcattag
     4141 taagaaaata ataatgactt ggttaaaaat ttgcccaatc gacattgcac cacttccttc
     4201 agtaaaaatc acaattacta ttttataaca aaaaggagaa tgattttact gaaggtgccg
     4261 acgctcattg tgatcaacgg caaaaggttc ttaataatgt attaacagga gcggaatcaa
     4321 tggcgaaatt attttgatat aatggcctta atgaataaga agaaaaaagt ttcatatgaa
     4381 actttttcgt ttacctttaa ccaccattta aaaacataaa acagctaaaa tagaagataa
     4441 gaaaatcgct tggagggtga aaaatgaata aggctgtaat tatgttagtt gaagatgaag
     4501 agagccttgc tagttttttg attactgaac tagaacttga aggctatgaa gtcatctggg
     4561 caaaagatgg gcgcgaggca ctagaaatat ttaaagagaa agaaataacc ttaatcttat
     4621 tagattggat gcttccaatt tatgatggtc tcacagttct acgccgaatt cggcaatcaa
     4681 gtaatgtgcc aattattatg attacggctc gtagtcaaac ttctgatatt agtatggcac
     4741 ttgatcaagg attagatgat tatattacta aaccgtttga gattgaggaa cttttagcac
     4801 gaattagggt tgtattacga cgattgggtc aaaaaaaagc agagaaatat gattataaat
     4861 ttagaccatt tgaaattaat ttactgaaac atcaatttat ggttgatggc aagcgggttc
     4921 atttaacgcc taaagaattt tccctcatgg ttgccctaat taaagaacca ggagtcgttc
     4981 aaacccgtga tgaccttctt aatgaaatat gggggtatga ttttgatggt cagaccaata
     5041 ctgttgatgt ctatattcgt gctttgcgca acaagttagg caaataccgc gacttaatta
     5101 aaacggtgcg agggattggt tatgtattag gtgatgagca atgagtaaca cacatccagt
     5161 aactgcatcg cggcaattaa ctcgtctttt cttaatgttg tttacagtga ttttagtagt
     5221 tattaatctt ctttttgtgg ttaccgccac taatttaatc tatcgttatg ctgatgatca
     5281 ggcagaagaa gtgattgaga caattgagga agattggccc gaaaatcaaa atcgcgaaac
     5341 ttttttgaat gcttatgttg ctcgtcaaga cgatgacgca atcgagatca ctgatggtaa
     5401 acgagaatat acctcaccca aagcccataa aatttttaaa cgaattgacc agcgaaattt
     5461 agcaatcaag aatctacagt taacccggca tggagtctat tatttacggc agcaaaaaat
     5521 agaccataat cgaatcgtca aagtagcaat taatgttgat gatttaatca aattaacagg
     5581 ctggctcttg atagtgacgc tgttaattaa ccttgcaata agtatcattg ctctccccat
     5641 cattcatcgt ttagctcgcc gatggacccg accattgact aatttagata atgaaattga
     5701 tgcaatcacg ccccaaagca atcgattgca aactttaacg gttccgcaac aaccattaga
     5761 ggtacgaaaa gttgcccagt cttttaatca tttgctagga cggcaatatc gtacaatgca
     5821 acgcgaaaaa gaatttattg caaatgcatc tcatgagttg aagacaccac ttgccggaat
     5881 tctgggacat gtaaacttga taagaaggca tggggataaa catccggaat taattggcaa
     5941 atcattaaag tacattgatc aagaagcgca acgaatgagt caattaataa atgaactgct
     6001 tattttagaa ggacaccaaa ccaaaaaatt aacagaaatt aacttatcga aaattatttt
     6061 cgctgaagtt gagtcactcc aaggggcata tcagcagaaa tttattactg atttaaatcc
     6121 gaatatatct taccggataa caaagggtga ctttcaaagt cttgtgcata atttattaga
     6181 aaatgcggcc aaatattcac caactgattc aataattgat gtgctgttaa cgacagatga
     6241 tcgccacata attttaagag ttgctgatca agggcgggga attgctaagg aaaatcggga
     6301 aaaagttttc gaaagatttt accgtgaaga tgaatcacac tccaataaga ttgctggttc
     6361 agggattggc ctggcgattg tcaaaatgat tatcgaaaaa tatcacggaa aaatcacgat
     6421 acgcgataat gaaccaagtg ggaccatttt tacggtttac cttccaaaat aaaaatgaag
     6481 atttcttcat catactttca ccggttcttg gttttagttg accgattatt ttgtagaata
     6541 aaattaccaa ttaaagttaa gaagggatga ataaaaatga ctgaaaaaat tgaaaaaaga
     6601 caagaccaac aaccaaagcc agacaagaag aaagcaagga agttcccaaa gatgactaaa
     6661 aaggttctga ttaccgcctg tgtttgtgga ggacttgtgt taggagctgg aggcattgct
     6721 ggtgtcgccg caatggatgg ttatcatgct caaatcgaag ccgcggtgaa acatgaaaag
     6781 ttagctaata agagcgacat caagattaac caacaggctg caattgatca gtttaacaag
     6841 aagtacccag ataagcacct caatgaagta gagctggaaa gtgacaaggg aaaatatgtg
     6901 tacaaggtaa agggctttga caataccaac gaatacaagg ttaaagccaa tgccaaggat
     6961 ggcaaactaa tctctaacaa gtctgaaaag cttgaccaaa atgagaagga atatacctta
     7021 gatccaggta aggcaattag ccgtgatgaa gcgagccaaa ttgccgaaaa agccgctaaa
     7081 aagggtagtg cgatcgaatg gaaattagaa caagaaaagg aaaatcaagc tgtttgggaa
     7141 gttaaagtaa aagatggccg gacagttaaa gaagttaaga ttgatgccgg ttcgaaaaaa
     7201 gtattagccg tggaaaacaa ccattaattt atccataatt tgcgccttca tcccccactt
     7261 ctataagtgg gggatgaatc gccttcttaa agcaacgagt gctttttctt cagttgctgg
     7321 tcatgtaata aatacgagga ggacaaaaat gttaaagaaa caccctttag ccttatatat
     7381 tacgtggata gttgctttag cagttattcc attaccgtta attatcttga caaatagtca
     7441 attaacagct gattatgaag atctttttgc ttatgatgtg gggatattgg cctatgtttg
     7501 gtggttggtt atcattttcc tctcaactcg tccaagatga cttgaaaagt atattggcat
     7561 cccttcaatg tattttttgc atgcttcgtt aggcgttgca gcgctggttg ctgcgactgc
     7621 tcacaaattt ttaagtcccg gcgctgatca ccttgttgaa acgacgggag atattgcttg
     7681 gtacttggca attgtcggta taatttacgc gattgtcttt atgtcgggat ggttagttga
     7741 ccgctttaag ctgcttcgtc aaattaaact aaagttaagc ataatttgct cccatcaagt
     7801 ttctgtctgg atccaccgct taaacttact attaatccta ctgatctggt tgcatgttca
     7861 cttaatagat gattttagcg agatgacaag ttttataaca acatttgatg cgtatactta
     7921 tatcattatt ggttattact tgttagcaaa gtttatcacg ctgtttaaaa caaatggaac
     7981 agtgatagcg aataaacagc ttgcaccgaa tactcaacag ttagtaatta agttagataa
     8041 aaacgatcca gcttatcaag ccggtgactt ttactttgta tcttttaggg gcagtaaatc
     8101 aattgggagg gaaaagcatc ctttttccgt tacgtccgcc cctaaaaata accctcatga
     8161 aattgccttt acgatccaaa aacttgggga ttttacaaaa aagatcccat cagtacaaat
     8221 tggaacaaga gtatatttag aaggaccata cggacaattt gatcgcatta tccgtaaatt
     8281 atctaaggat caaccattag tgttttacgg gttaggatca gggttagcac cccttcttag
     8341 cttggcagaa caatatggaa atcaacgaca aataaaaata ttatggtctt catcaaaaaa
     8401 gaacggccta tattttgaaa aagccctgga aaaattaaag aaaaatccta atattacggt
     8461 tattgcaaaa gaaggtcgtt ttacggaaga atcaataaaa aaagaattgt cacctaaaga
     8521 aattgatcaa gggctctact ttatcgtggg accagctcat gtcatcttaa atgtcgaaaa
     8581 gatgcttcgg aaacttaatg ttaagtcacc acacataatt gatgaaagat taacaatgta
     8641 ataatgataa tatgcaacca atcgcggggg tacggagtca atctcaagtt aaagattctc
     8701 gatcaaggaa ttgaagcacg ggctgatatc gttcgggaaa acagttgagg ctgggagaaa
     8761 atgaatcgca ccctgtcaag tgaacatgta aatatataaa gtctttaaac agcttgattc
     8821 cggtattcta ctgggattaa gctgtttaat tggatatctg tcaactggta tggttgacag
     8881 atatccatat atttccatgt tcacctagaa gggagcatac cagaattgtg taaagtccac
     8941 ggcaatcgtc attactttaa tgtggtattt gttagtaata tcatactcga gctgggcaag
     9001 ctttttgcgg atttcgtccg actaaaacca ggttaccgcc tttttgtgca tggatcttaa
     9061 caaattccat tcccagacca ccagtggtac cagtaattaa agcagtttct tttgacataa
     9121 taattcttcc tcaaaatctt atccttcatt tgatgttgat cacattatag gttgaagaaa
     9181 aggagaagta atatcatatg atgccagtgg ctaatttgta tcaataatta gtacgtaatt
     9241 taacggcgtg ggcccctact ttattgttag cggttgagct gggatcgtgc agccaataaa
     9301 aggaaggctc tttttacaag atcaaatcac aataggccga aaataaaaaa atgcaccatt
     9361 aaagacacgt tttaaattaa ttttttaatc gtcccatact tttttagcaa cgttgaatgc
     9421 ggaccaagca ttaggtcagc cgacgtaaaa ggctaattga gtaataattt ctgcaatttc
     9481 atcttttgta atactgttgt tcttagcagt ttgcatgtgg taagggagtt gttcaaaggc
     9541 accctttgta atcaacgcgg taacggtgag aagactccga tcacgaaggc ttaattcctt
     9601 ttcccgtgac caaacctgtc cgaataatac atcatcattt aattctgcaa atttaggggc
     9661 gaaatcacca agttggtcgc gaccagctgt ttgtttctta gccatgaaaa tctccctttc
     9721 tcaatcgtaa ttttgattac ttttactata agcctagaaa gctaaaattt aaaataccaa
     9781 tattaagtag gcaataatgc aaaaaatgaa tagctagcag tttttatttg taactaataa
     9841 aataaggcaa gacaaaaacc tttgaataat agtgcgatta atgtcttgtt agtaagacat
     9901 tgaaagatat aatgctagaa agcaaaaatt aaaacatgaa atacaggtac tgtaccctgt
     9961 caagttgaca agttaaataa taaaaattta gttggcctta ccaaagcgga attctgcagc
    10021 ggtaaggtca tttcttgttc ctgaaataaa tttatgggtg aaataattga tcccatctct
    10081 aacttgctgt tctaactcaa ccaatgtttg tgctttaggc atatgggcaa tccatattgc
    10141 cttaaaatcc gcccaccaat attcaattac tgcattatct gctggggttc tcggtgccga
    10201 atagctatgg cttgcaccat taattgctag atattggtta aaagctcttg acgtataagc
    10261 tgctccgcga tctgtatgaa ttaatgacgc tactttacct tcactagctt gcgcttgttt
    10321 gaacactcga attgctcctt cggatgtttc tgttggcgta attagccaac tgatgggata
    10381 ttgcccatat aaatctaata cagcatgtaa acgaacctta ctataacgaa taccacttct
    10441 ggattattga atgagcctaa aagtccagat atagtattga atccttcttt gttcataatt
    10501 aattttgttt ctttaatggt tgttttttcg actattatag ctatattcat tgttgattta
    10561 cttacatcta ttccaaatac acaacgtatt tttacatctc cgtgaagttc aaatcattta
    10621 ttatcttaca atctaatttt ctatactcga cttcaatagc caacagacta agaccagact
    10681 tttgtaaaat taaacgaaat tgccattttg cgatgcgaca ttcaatgccc aaaaaatttg
    10741 cgacatgtca acttcgtttc ctactctaac aaaaaagtag tgagaattca gatccgtcaa
    10801 tctgaattct cactactaag cttagtctgt tttctaatat taggtccatt cattacaaat
    10861 ggtcccgtta tttaattggt aaaggtaaag ccattagaat taggtatagt attcttttcc
    10921 ataatggcca ctttttatac tttaagatat cgtcaaacat ggggacacct tcttctacat
    10981 aagcgcaaac gataactttt ctagtttttg tattaagcat aacgtgttct actgctagga
    11041 gcaactttaa tttcagctga acttcagcaa aaaaactatt taataaaaat aatcctaaaa
    11101 attaggtggt actagtggaa gtattttaat agccaagttc cgctaacgga aacaataggt
    11161 attagccaaa taattgtaaa acgatttgtt aaatgcttac taactaattg ataaataaaa
    11221 ttgatcataa tattacctct ttgtaaagta aatataaaat aattaaaaaa ttcattgatt
    11281 gaaagatgtg ggttagtaag agtctatatt agtacttctg aagtagatta aaatacagac
    11341 cgtgctcttt aagtagttga ttgtgagttc cttgttctac gattgttcca ttatcaatta
    11401 cagtaatatt atttgtaatc tttgcgattg aaaggcggtg agcaataaag ataatagtct
    11461 ttgaagttag attcataaga ttcttgacta gcttttcctc tgttatgatg tctaatccac
    11521 ttgtcgattc atcgagaata atgactttgg ctggggataa caatgcacgg gcaactgtaa
    11581 gacgttgctt ttgtccacct gaaagagtag tagcattttc gtctagttta ctatcatatc
    11641 ctaacgatag gtgcataatg tcgtcatgaa tcatcgcaac tttgcaggct ttagtaatgt
    11701 cttcatcagt aatgtctgtt ctacttccta gaagtaagtt ttctttaatt gttccagaga
    11761 atatataagg attctgagga atatagttaa taaaagatcg cacagttgtt ttgtctatat
    11821 ctaaaatgtt taaaccatta acaagaatct gtccacttgt aggattgaaa taatttacca
    11881 agagcttcat caatgtggac tttcctgaac cactcatacc gacgactgtc attttagtac
    11941 ctggcgtaat cttccaatta atatctttta gaataggatg attatattga taactataat
    12001 taacattttt gatctcaata tcgccattag ttattttatg agataacttc tttttgatga
    12061 attcgtcttg taccatgtaa acctcattta aacgattatt tgccacttga gcactttgaa
    12121 ttttaggctg taaattaata atattttgga gtggtgtaat aaagtataca aggagtgcgt
    12181 tatacgtcat caattgtcct attgtaaatt ggttgttaat aacttgaatt gcaccgaacc
    12241 aaagaatgat gaggctaaac gctaattgag taaagctttt aaggctctgt tgaatactat
    12301 ttaatttagt gtgtgttaat gatttatgta aaaaatcatt aaactcattt tcaattttag
    12361 ttaaacggtt ttcttcacta tttagtgatt taatagtttc aattccacgg atatcttcta
    12421 taattgatgc acttacagta gcattacttt ccatttcttt ttggtttaga actttgaatg
    12481 agtgggtaaa agaacctatt atgacaaggt atacgggaat tgtaattaaa gttagtataa
    12541 atagttttaa attttgaatt gccagagtaa taccaataat gcatagcata gttgtgtcta
    12601 gaaaaataga tattatagaa ttaacaagag catcaattac tttattagca tcagtaaacc
    12661 ttgaaactat atctcctgtt tttctggttg aaaagaattc catggggagt ttaagaacat
    12721 gcttaatgta atctagaaga atagttttcg atagtctttg acctagagtt gctaatagat
    12781 aatctcttgt aaagttaaac aatgaatttg ctacatatgc tattagtaat ccaatacaaa
    12841 ttatgtttaa aggtgttagt aatttataag ggatcaatct atcaattaag ccttggaaaa
    12901 agtatgagct tattatattg ataaatgtta ctaaaaatgc tgatgtaaca atgcctatta
    12961 ataacttctt ttgctctatg acaggaatga ttaacctctt tagtgtaggt gattgttctt
    13021 gaataatttc ataatcatta gcaggattag cgaaaattgc aattccggtc cattcttgaa
    13081 agaaagcttc tttagatacc ttttgaactt ttatgtttgg atttggatct gcaataataa
    13141 gatgattttt tgcgttttta acgactacac agtaatgtaa taagccggta tcctttttaa
    13201 tgagatgtgc aataaaaggg taagaagctt cgttagagct aaaaagattt atatctgctt
    13261 gataagcagc aacgttaagc ttatactttt tagcggcttc gacaatacct aaagcagttg
    13321 taccttcagt agttgtttta gtagcttttc ttaaagttgc aagtgaaact ttagagccaa
    13381 atttacgaag aatcatggat agtgcggcta ctccacaatc tgcttcgtca acttgactta
    13441 catagtattt attaaatgcg ttatacataa aaatacccca ctaatctaca atttctcctt
    13501 atagatttta tttagttctt ttgttcgact acgggaaaat ttgattttat cgccattgat
    13561 aaacgttacg attcggcttt ttgtattgat tgattcaata ttttgcggat tgatcagagc
    13621 tgattgtgat gccttaaaaa agaacgaata attctgttca acatctttta tattgccgga
    13681 aaattctcct tgcccattaa tagttactat ttttagctta tgtggaaact tagtagtagt
    13741 aatgtaaaga atattattga aatttacgtt tataattctc gtaccaattt tatatttaaa
    13801 tgtgtgtgtt tgaatataaa attggttaag gtgcctaatt gctaactcta atgtttctgt
    13861 taatcgccgt tgcaattttc gttggtcagt tgtcttgaca atataatcta atggattaat
    13921 tcgtctttga aaggtaagaa aagcaagttc ttcatgggtg gtaataaaga taatttgggc
    13981 gttacggtgc tttttttgaa tttgctgagc taatgctaaa cctgcttgag attgtttgtt
    14041 ttcgtctaat tgaatatcca agaacgcaac gatattagtt aagtctggat tagattctag
    14101 ataatctaaa atactagctg catcagtggc aattagatcc acattagggt gtatatcgtc
    14161 ttcttccaga ataattgacg acatttttaa taatgtggca atatttttag cttgtagctg
    14221 gtcatcatcg caaacgagta gatggtagtc cataagtatt cctttctatt caattgaaat
    14281 tgtaaatgta aagtaaccat tatcggagga gtaagcaata tatacgttgt ggtatttgtt
    14341 agctattttt tgagccgttg ctaatccaag tccctcatgg ttagtcttat ttgtaattcc
    14401 ttcttgatga agcttattgg tgctaagctg ctttcgacaa gt
//
