LOCUS       c00039_gnlPro..        15990 bp    DNA     linear   UNK 01-JAN-1980
DEFINITION  gnl|Prokka|MADBFOCO_45.
ACCESSION   c00039_gnlPro..
VERSION     c00039_gnlPro..
KEYWORDS    .
SOURCE      
  ORGANISM  
            .
COMMENT     ##gutSMASH-Data-START##
            Version      :: 1.0.0-1555cd7(changed)
            Run date     :: 2025-04-29 16:32:46
            Original ID  :: gnl|Prokka|MADBFOCO_45
            NOTE: This is a single cluster extracted from a larger record!
            Orig. start  :: 0
            Orig. end    :: 15990
            ##gutSMASH-Data-END##
FEATURES             Location/Qualifiers
     protocluster    1..15990
                     /aStool="rule-based-clusters"
                     /contig_edge="True"
                     /core_location="[2777:5990]"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
                     /tool="gutsmash"
     proto_core      2778..5990
                     /aStool="rule-based-clusters"
                     /tool="gutsmash"
                     /cutoff="10000"
                     /detection_rule="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /neighbourhood="10000"
                     /product="Arginine2_Hcarbonate"
                     /protocluster_number="1"
     cand_cluster    1..15990
                     /candidate_cluster_number="1"
                     /contig_edge="True"
                     /detection_rules="(Amidinotransf and OTCace and OTCace_N
                     and AA_kinase)"
                     /kind="single"
                     /product="Arginine2_Hcarbonate"
                     /protoclusters="1"
                     /tool="gutsmash"
     region          1..15990
                     /candidate_cluster_numbers="1"
                     /contig_edge="True"
                     /product="Arginine2_Hcarbonate"
                     /region_number="1"
                     /rules="(Amidinotransf and OTCace and OTCace_N and
                     AA_kinase)"
                     /tool="gutsmash"
     CDS             complement(153..758)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_1"
                     /sec_met_domain="LysR_substrate (E-value: 9e-19, bitscore:
                     58.2, seeds: 361, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKKLRIAYFNQLGRRQLDRIVDQFKQKHSDVEIELIGMGHDEAFD
                     KLAKNEVDLAISDLRDDQLDFKKEILGQEAVMAILQKGSYPSGVQMINKDDLADLTCFI
                     VAKPEEEAAELHLFKDIYQIRSPFIASNSVEEAALLVASGSGYFLMNEATASLISNDTL
                     QRLFLLSNGQQMWQKIAAFYTNEDAVIKDFILLAKKVY"
     CDS             complement(761..922)
                     /locus_tag="ctg39_2"
                     /transl_table=11
                     /translation="MSKQKKVRLLKFLSVVVSGINVVISLLIMFNKYQIRKDKKQISDE
                     GHAPLDEN"
     CDS             complement(938..2104)
                     /locus_tag="ctg39_3"
                     /transl_table=11
                     /translation="MKLKKNQDNLKQIASLIEYAFLKDSDLTTDSNFMPRYDHSDGYGY
                     FDQEKLTSYMMVNKFKAEIFGHHVPLAGIGYVASYPEYRGRGHISKLMKEILFDLHDQK
                     IPVANLAPFSEKFYRHYGFSNSIYQKEYRFSGAALASFRLPRKGKIIRGKWNDLIVQNG
                     VIQLYERQLHTDDERNTIIREAWWWNRLDDYYHHREIAVYFDEAGRPMSYLIYRIIDNC
                     FMADELYSITPQGLLSILGFMAAHIGSIKEFCMTLHEKSLLAELFPEQNELDIQLHPYM
                     MSRIIDFQKVLACMRPLQEGTFNIEVNYDDQCPWNIGVWQLTNYDHQVKCERKEDELVD
                     FSGPITTWTQILLGRLTMESAIKLGLITDYRIKKLDFVKGKVSFYDYF"
     CDS             complement(2225..2761)
                     /locus_tag="ctg39_4"
                     /transl_table=11
                     /translation="MNIFQEGNPQNIAQVLAGKDYRVALQQAIFKKYPDATLVDINLNI
                     PGPIKNNRYLIKLFDYGIKQLEEIWQNNGYDYKLVKALNNDAGCENFYVLRESSKVVKL
                     STILFEENNKIGRLFDADVLIKGKTALSRQELEYSSRRCYLCNRPAKECARSRRHSVEE
                     MQRYISSLYAKYVNN"
     CDS             complement(2778..3119)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_5"
                     /sec_met_domain="AA_kinase (E-value: 3.3e-19, bitscore:
                     60.0, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VKDDSLQGVAGVIDKDFSAAKLAEDIQADELVILTTVDNAYVNYN
                     QPDQAPIGKIKIDQLKKYLEAGQFAAGSMKPKIEAVIDFVEKTGKTAIITSLRNASKLD
                     DGVGTIVYN"
     CDS             complement(3288..3710)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: AA_kinase"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_6"
                     /sec_met_domain="AA_kinase (E-value: 4.4e-13, bitscore:
                     39.9, seeds: 128, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MKRIVVAFGGNAIEAGDNSAAAQEKQVKKTMKVVAKMIENGDQVA
                     IVHGNGPQVGNLLLQQYKGSSKDNLAMPLDTVVSMTQGSIGYWMQKALDDQFKHTNYPH
                     QAVALITQIIVNANDPTFKNPTKLIGPFYTFNEMQR"
     CDS             complement(3905..4513)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace_N"
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: OTCace"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_7"
                     /sec_met_domain="OTCace (E-value: 1.9e-37, bitscore: 119.4,
                     seeds: 50, tool: rule-based-clusters)"
                     /sec_met_domain="OTCace_N (E-value: 1.3e-24, bitscore:
                     77.5, seeds: 1463, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MGAGEIHLGKKESIEDTAKVLGSMFDDIEYRGFAQKDVEDLAKYS
                     GVPVWNGLTDKWHPTQMLADFMTIKEKFGHLKVLTLAYVGDGRDNVADSLLVAGSMLGV
                     NVHIVTPKPLFTHPDVQKIAEGFAKDSGSRNLITDDIEQGVKGANIIYTDVWVSMGEND
                     WSERIKLLKPYTVTMNMMYMTGTPDDQLIFMHCLPAFHD"
     CDS             complement(4612..4749)
                     /locus_tag="ctg39_8"
                     /transl_table=11
                     /translation="MKYLQNVFQGRSLLKCKDYTPTELNYLIDFALHLKELKKIFRMNI
                     "
     CDS             complement(4761..5033)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_9"
                     /sec_met_domain="Amidinotransf (E-value: 7.6e-31, bitscore:
                     97.9, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="VLKNYLHLSEIDLIPTGGGDAIAAPREQWNDGSNTLAIAPGEVVT
                     YDRNYVSNDLLRKHGILVHEIHSSELSRGRGGPRCMSCPLVREDL"
     CDS             complement(5263..5673)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_10"
                     /sec_met_domain="Amidinotransf (E-value: 2.6e-28, bitscore:
                     89.6, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MDYLIAMPVNEMVKQIIAGIRKNEMQNATPSLADLAENPDYPFYL
                     DPMPNVYFTRDQQATIGNGMTINRMTFRARRRESLFMETVLKHHPDFKNANIPIWCDRY
                     THGRLEGGDELILNNHVFSNRYFSKNFRCRNH"
     CDS             complement(5805..5990)
                     /gene_functions="biosynthetic (rule-based-clusters)
                     Arginine2_Hcarbonate: Amidinotransf"
                     /gene_kind="biosynthetic"
                     /locus_tag="ctg39_11"
                     /sec_met_domain="Amidinotransf (E-value: 1.9e-11, bitscore:
                     34.2, seeds: 31, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MTDLIHVYSEIGKLETVMLHRPGRELENLSPDILNRMLIDDIPYL
                     KIAQKEHDYFAHTLEK"
     CDS             complement(6063..6917)
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) LysR_substrate"
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) HTH_1"
                     /gene_functions="regulatory (smcogs) SMCOG1012:Bacterial
                     regulatory helix-turn-helix protein, lysR family (Score:
                     72.5; E-value: 6.7e-23)"
                     /gene_kind="regulatory"
                     /locus_tag="ctg39_12"
                     /sec_met_domain="LysR_substrate (E-value: 2.1e-28,
                     bitscore: 89.7, seeds: 361, tool: rule-based-clusters)"
                     /sec_met_domain="HTH_1 (E-value: 2.5e-23, bitscore: 72.5,
                     seeds: 1330, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MNIKQLRYFLVVAKEKQITSAAKRLYIAQPPLSYQLKQLEIELGA
                     QLFKRTAHGIELTDAGQILQSYASEILSLSESVKNQVHKTVSGELGTIAIGMASSSTGL
                     IPMKSFQDLTKFYPEINFDIYEDNTFGIIDKLEKKTIDLGIVRTPYNRNGLNAKTLTTE
                     RMMAVTVDPKFKDKTGLRIKDLNEQPLIIYRRFEEIFNQTFAHHGIKPFYAVKCDDSRT
                     AITWAKRKMGIALVPESIASTYAPDDLIPIKYSNWITHLQLVRRKDQKVTPLMKRIIDS
                     LSR"
     CDS             7046..9319
                     /locus_tag="ctg39_13"
                     /transl_table=11
                     /translation="MSEKFHGLTQAEADKRLKEDGLNEAPEPEYNFFKEFLSKLWNLSA
                     WVLEGALILECILGKWIQSLFVLLMLLFAAFNGASKKKQSRRVLNTISHKLTPKVAVER
                     DGKWIKIDSKQLVRGDLISLQRGDVLAADVKMVSGKIACDESSITGESKPVKKNIDDTA
                     YAGTTVVEGDGLAIVTATGKDSRSGKTINLINNSAAPGHLQQLLTKIIYYLCLLDGVLT
                     LVIIIASFFKGGNFDTFINMLPFLAMMFIASIPVAMPSTFALSNSFEATRLSKEGVLTA
                     DLTGIQDAANLNLLLLDKTGTITENKTAVASWSNLSDLPDKDVLALVGSATDKRNAGII
                     DIAIDEYLKENDIPVMDVEHFTPFTSDTGYSMAEVDGHNVKLGSFKQLSLIDKNANEAV
                     EGINFKAGRSVAVLIDDKLAGVFILQDKVRKDSKAALAELKKRGVRPIMLTGDNQRTAA
                     AVAEQVDLTGNVISIHDFDESTDIDELAGIADVLPEDKLKMVKFFQEKGYIVGMTGDGV
                     NDSPALKQAEVGIAVSNAADVAKRSSKMVLLDDGLSSIVKILDAGHRVYQRMTTWSLAK
                     LARTAELTMLLTFGYLFFNYIPMALNAMVIYTIMNNMVTMMIGTDRTHITYKPENWNMA
                     RLAKIAFSLAAGWTVIGIAFFSYLNMHGWSHNSISTMVYVYLVLSAMLIVLITRTRKYF
                     WQDYPSKLVGIVQIADVALTFILALCGLAMAQISWQNLLITVVVALIAAIIIDLIYQPV
                     MKNR"
     CDS             complement(9388..9885)
                     /locus_tag="ctg39_14"
                     /transl_table=11
                     /translation="MRKQIISAAGIMLAVIGLGAATTQSVDAVVTNPVRQGKRLNLTRN
                     ATVYNRHGVKVGHLRKGKLYKVRAIKVINGNTYVKIRKNRFVKEEAFLPYMKTTVKVVN
                     RIKKHSFVYDENGEKIPGKFLKRGAKVNYLGHKEINEKPFIKIADGEYVKALNALTTVT
                     NY"
     CDS             10147..10713
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_15"
                     /sec_met_domain="PLDc_2 (E-value: 2e-09, bitscore: 28.1,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MLVLTVLPGIGFILYLFFGRQLSHDEIFAIQEEQKKVQRHYLAEQ
                     RDMLKEHDLLPEKERLPRVRMLSELNLNNDDAILTFDNQVKVFISGPELFDQMITDIKN
                     AKKSVSLELYTFYSNQLGHRVLKALEEAAANGAKVRVIYDTSGSRGTKPSFFDHLRAAK
                     LSHLFPLQKSTGLLPHDSITTYIEN"
     CDS             10951..11508
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PLDc_2"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_16"
                     /sec_met_domain="PLDc_2 (E-value: 4.4e-28, bitscore: 88.4,
                     seeds: 83, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MIIKMSLCKLFPQDLIINITASDEAEGIIAGAKKYIYIQTPYLIP
                     EESILEALIIAANSGIDVRIMVPCMPDHPFVYRATEYYAKYLVAHGVKVYKYNDGFIHA
                     KTMVSGSNISSVGSANQDFRSYTLNFEVNSFNYNPALTQELKKIFEKDLDKCTLLTNDY
                     FAQQSSWLKFKQYFSRLLSPIF"
     CDS             11639..12433
                     /locus_tag="ctg39_17"
                     /transl_table=11
                     /translation="LANRVKIGVLNLMHDKLDTQQRFARVLPDADLTFFYPRMHYQNRP
                     VPPEVAKTSQPLDLNQIKEFDGFIITGAPLDHLDFDQVTYIEEVRCLLQLLDKYKLQQL
                     YFCWGAMAALDYFYNIQKRILSKKIFGVFPHLIIEPHPLLNGLSKGFIAPHARYAEMDK
                     TQIMQDPRLTINSVDDNGHLFMVSSLEKPEQNFIFSHIEYGRKGLKKEYEREIAAHPER
                     HYKKPENYSLSNLLFQWKDTQKTFFNNWLTQVKKSKLVLLDK"
     CDS             12449..13378
                     /gene_functions="biosynthetic-additional
                     (rule-based-clusters) PALP"
                     /gene_kind="biosynthetic-additional"
                     /locus_tag="ctg39_18"
                     /sec_met_domain="PALP (E-value: 5.9e-69, bitscore: 223.2,
                     seeds: 146, tool: rule-based-clusters)"
                     /transl_table=11
                     /translation="MSTIYNSVTELIGNTPLLKLNRVVPDDAADVYVKLEFENPAGSIK
                     DRIALAMIEKAEREGNLKPGGTIVEPTSGNTGIGLAMVAAAKDYHIIIVMPETMSVERR
                     KLMKGYGAELILTPGADGMKGSIAKAEELVKEKGYFMPMQFENTENPNIHELTTGPEII
                     AAMNGIGKSVDAFVAGVGTGGTLSGIGHALRRENPSTKIFALEPTESPLLKDGKTGKHG
                     IQGIAAGFIPKNLDKDIYDDIITVSTDEAMATAREVAKNEGFLPGISAGANIHGAIEIA
                     KKLGKGHAVVTVVPDGGDRYLSTALFNA"
     CDS             complement(13522..14049)
                     /locus_tag="ctg39_19"
                     /transl_table=11
                     /translation="MAIDFSKYIASVKDFPNKGIVFRDITPILQDGELYRIATHELAEY
                     AKSRKADVIVGPEARGFIVGCPVATELGLGFVPARKPHKLPREVERASYDLEYGSNSLE
                     MHKDAIKPGQRVVLCDDLMATAGTLRASKELIENLGGKLVGAAFYIELPDLKGREKLPD
                     VDIYSLVQYHGA"
ORIGIN
        1 gagtccattt tgacctcgtt tctaaatgtt gtgtggtaac tacattctat caaacaggtc
       61 cgaatggact ttttattttt tatcaagtgt tcaacttaat tttacaatca gcgcattttt
      121 atttttacag tattttgctg ttccaagata gattaatata cttttttagc taacaaaata
      181 aaatctttaa ttactgcatc ttcattggta taaaaagctg caatcttttg ccacatttgt
      241 tgtccattag acaataaaaa caatcgttgt aaagtatcat tactaattaa actggcggtt
      301 gcttcattca ttaaaaaata tcctgatcca gaagctacta acaatgctgc ctcttctacg
      361 gaatttgaag caatgaatgg gcttctaatc tgataaatat ctttaaataa atggagttct
      421 gcagcctctt cttcaggctt agctacaata aaacaggtta aatcagctag atcatcttta
      481 ttgatcatct gaacaccgct aggataacta cccttttgca aaatagccat tactgcttcc
      541 tgacctaaga tttctttctt aaaatcgagc tgatcatcgc gcaaatcact aatcgctaaa
      601 tcaacttcat ttttggctaa tttatcaaaa gcttcatcgt gtcccattcc aattaattca
      661 atttctacat cagaatgttt ttgcttaaat tggtctacaa ttcgatctaa ttgtcttcta
      721 ccaagttggt taaagtatgc tattctcaat tttttcatag ttaattttca tccaatgggg
      781 catgaccttc atctgatatt tgttttttat cttttctaat ttgatatttg ttgaacataa
      841 tcaatagcga aataaccaca tttattccac taactaccac gcttaaaaat tttagtaatc
      901 taactttctt ttgcttactc attttggata ccttcttcta aaaataatca taaaatgaga
      961 ctttaccttt tacaaagtcc aactttttaa ttcgataatc tgtgatcaaa ccaagtttaa
     1021 ttgcggattc catagttaaa cgtcctaata agatttgagt ccatgttgta attggaccag
     1081 agaaatcaac tagttcatct tcttttcgtt cacacttaac ttggtgatca taattagtta
     1141 attgccaaac gccaatattc catggacact gatcatcata attaacttcg atgttaaaag
     1201 taccctcttg caatgggcgc atgcatgcca agactttttg gaaatcaata attctactca
     1261 tcatatatgg atgaagttga atatccaatt cattttgctc tggaaaaagt tcagccaata
     1321 aagacttctc atgcaatgtc atacaaaact ctttaattga ccctatatga gctgccataa
     1381 agcctaatat gcttaataat ccttgaggcg taattgaata taattcatca gccataaaac
     1441 agttatcaat tatgcgataa atcaagtagc tcatcggccg accagcttca tcgaagtaaa
     1501 cagcaatctc tcgatgatga taataatcat ctaatctatt ccaccaccaa gcttctctga
     1561 tgatcgtatt tctttcatcg tcagtatgca actgacgttc atataattga atcacaccat
     1621 tttgaacaat caaatcattc cattttccac gaattatctt acctttgcgt ggtaatctga
     1681 aagaagcaag tgcagccccc gaaaagcgat attctttttg gtaaatacta ttgctaaaac
     1741 cataatgacg ataaaatttt tctgaaaatg gagctagatt tgcaactggg attttttgat
     1801 catgcaaatc aaaaagaatt tctttcatta atttagatat atgtccacgt cctctgtatt
     1861 caggatatga tgccacataa ccaatacctg ccagtggaac atgatgacca aatatctcag
     1921 ctttaaactt attgaccatc atataactgg tcaatttttc ttgatcaaaa tatccatatc
     1981 catcactatg atcatatcgg ggcataaagt tactatctgt agtcaaatca gaatctttta
     2041 aaaaagcata ttcaatcaat gaagcaattt gttttaaatt gtcttggttt ttctttaatt
     2101 tcatagtttt ccttacaata tatattcata actttactta tattttagaa cattttatgt
     2161 atttttcgtt agcttttttt aagatttaaa tgaaaaaacg ggatgattag cctcccatcc
     2221 cgttttaatt atttacatac ttcgcatata aactagaaat gtatctttgc atctcttcta
     2281 ctgagtgtcg ccgtgatcga gcacactctt tagcagggcg attgcataaa tagcagcggc
     2341 gactagagta ttcaagctct tggcgtgaaa gtgcagtttt ccctttaatt aatacatcgg
     2401 catcaaataa tcgtcctatt ttattatttt cttcaaataa aattgtagat aatttaacta
     2461 ctttgctaga ttctcgcaaa acatagaaat tttcacatcc agcatcatta tttaatgctt
     2521 ttactaattt atagtcatat ccattattct gccatatttc ttctaattgt ttaattccgt
     2581 aatcaaataa tttgattaaa tatcgattat ttttaattgg ccccgggata tttaagttta
     2641 tatcaaccaa agtcgcatca ggatactttt taaaaatagc ttgctgcaaa gctacacgat
     2701 aatcttttcc agctaatacc tgagcaatat tttgcggatt tccttcttga aaaatgttca
     2761 tttatatctc accgcagtta attataaaca attgtaccta ctccatcatc aagtttactt
     2821 gcatttctta aagaagtaat aattgcagtc tttcctgttt tctctacgaa atcaatgaca
     2881 gcttcaattt ttggcttcat gctgcctgca gcaaattggc cagcttctag atacttcttt
     2941 aattgatcaa tctttatttt tccaatagga gcttgatcag gttgattata gttcacgtag
     3001 gcattgtcaa cagtagttag aataactaat tcatctgctt gaatatcttc agctagtttt
     3061 gcggcactga agtctttatc aattactcct gctacgcctt gcaaactatc gtctttcact
     3121 acaacaggaa ttccatcacc tccggcagca ataggaacaa acttgctctt tagtaaagtg
     3181 tcaatgcctg gtgcattaat aattttaacg ggctttggag aagaaactac ttgacgatag
     3241 cctcgacctg tatcttgctt ataagtatat tcaggatgat agatttttta cctctgcatt
     3301 tcgttaaatg tataaaatgg gccaattagt ttagttggat tcttaaaagt tggatcattc
     3361 gcattaacta ttatctgagt aattaaagca acagcttgat gtggataatt tgtatgttta
     3421 aattgatcgt ctaaggcctt ttgcatccaa tagccgatac tgccttgagt cattgatact
     3481 actgtatcaa gcggcatagc gagattatct ttacttgaac ctttgtattg ttgcaaaagc
     3541 aaattaccaa cctgcgggcc attaccatga acaatcgcta cctgatcacc attttcaatc
     3601 attttagcaa caaccttcat tgtcttttta acctgctttt cttgggcagc tgcactatta
     3661 tcacctgctt caatagcatt gccaccgaaa gctacaacta ttcttttcat ctttatttac
     3721 ttccttcatc aactgacgga ataaacaaat tgcccaaagt agcggccatt attgctttga
     3781 tagaatgcaa tctattttcc gcttcagtaa attgccaagc gtattgagag ttaaagactt
     3841 catctgtaac ttccacttca cttagaccat atttttcata aatttctttg ccaactttag
     3901 cagttcaatc atgaaacgca ggcaaacagt gcataaagat tagttgatca tccggggtgc
     3961 ctgtcatata catcatattc attgtaaccg tgtaaggctt taacaatttg attctctcac
     4021 tccagtcatt ttcacccatt gatacccaga catcagtata aataatattt gcacctttaa
     4081 cgccttgttc aatgtcatca gtaatcaaat ttcttgatcc agaatctttg gcaaaacctt
     4141 ctgcaatttt ttgtacatca gggtgagtga ataaaggctt tggcgtaact atgtgtacat
     4201 taactccaag catgctgcca gccactaaaa gactgtcggc aacattatca cgtccatcgc
     4261 ctacataagc taaagtaagt acctttaaat gtccaaactt ttctttaata gtcataaagt
     4321 cagccaacat ttgggtcgga tgccatttat ctgttaaacc attccaaaca gggacaccag
     4381 aatatttagc caaatcttct acatcttttt gagcaaaacc gcgatattca atgtcatcaa
     4441 acatactgcc caaaaccttg gcagtatctt caatactttc ctttttacct aaatgaattt
     4501 caccagcacc catatattca ggatttgcgc ctaaatcatt gcatgcaact acaaaggctg
     4561 aacgtgttct tgttgaagat ttttcaaata aaagagctat attctttcct tttaaatatt
     4621 catgcggaat attttcttta gttccttcaa atgaagtgca aaatcaatta gatagttaag
     4681 ctccgttgga gtatagtctt tgcattttaa taaacttctg ccttgaaaca cattttgtaa
     4741 atatttcatt ttgacgcctc ttacaaatct tcacgaacaa gtggacatga catacatctt
     4801 ggacctccac ggccacgaga aagctcactt gaatgaattt catgaactaa aatgccatgc
     4861 tttcttaaca aatcatttga tacataatta cgatcatatg taacgacttc acctggcgca
     4921 atagccaaag tattcgagcc atcattccac tgctctcttg gggctgcaat tgcatcccca
     4981 cctccggttg gaattaggtc aatctccgat aagtgcaaat aattctttaa cactttgatc
     5041 aaatcagttt ctggggtaat tttaatctca ccatgatcat cttgctctaa aacataaata
     5101 tcaatctttc ctgatttgtc taaaataaaa ggatgaacag tacactaatc ataattaatc
     5161 attgtaaaga ctgtatccag atgcatcatg gcatgattat gtggtatttt aattgctaaa
     5221 attgtgtcat aactagaatg accaaacagg ctatgagcaa ggtcagtgat tgcggcagcg
     5281 gaagttcttt gagaaatacc gattgctaaa aacatgattg tttaaaatca gctcatcgcc
     5341 accttctaaa cgtccatgag tgtaacgatc acaccaaata ggaatattgg catttttaaa
     5401 gtcgggatga tgctttaaaa cggtttccat aaataatgac tcacgtcttc tagctctaaa
     5461 cgtcattcta ttaatagtca tgccattacc aatagttgct tgttgatcac gagtaaaata
     5521 cacatttggc attggatcca aataaaatgg ataatctgga ttttcagcta gatcggctaa
     5581 tgaaggagtt gcattttgca tttcattttt tctaatacca gcaattattt gcttaaccat
     5641 ttcatttact ggcattgcta ttaaatagtc catcagtaat tgatgtaatg gatcttcttt
     5701 tttatattgg attcttctaa taattgatct acaaattttg tacggacatc ttcattagtc
     5761 aaagagtgag ctaataaatc ttctaaataa acgacatgaa ctccctattt ttccaaagtg
     5821 tgggcaaaat agtcatgctc tttttgagct atttttaaat atggaatatc gtcaattaac
     5881 attcgattta agatatccgg tgaaagattt tctaattctc ttcccggtcg atgcagcata
     5941 actgtttcta atttgccaat ttcggaataa acatgaatta agtcagtcat tatagcgcct
     6001 cctaattcaa attatgtatc agcttacaat aattaaggat caattaggta gaagttacaa
     6061 tcttaacggc ttagtgaatc tattattctt ttcattaaag gcgtcacctt ttgatccttg
     6121 cgcctcacta attgcaaatg cgtaatccaa ttactatatt taataggaat aagatcatca
     6181 ggtgcatacg tagaagcaat agattcagga acaagagcaa tccccatttt tctcttcgcc
     6241 caagtaatcg ctgttctaga atcatcacat ttaacagcat aaaacggctt aatcccatga
     6301 tgagcaaaag tctggttaaa aatttcttca aatcttcgat aaataatgag gggctgctca
     6361 tttagatctt taatccttaa tcccgtctta tccttaaatt tgggatcaac agtaactgcc
     6421 atcattcttt cagtagttaa agtttttgca tttaagccat tacgattata aggcgtacgc
     6481 acaattccta aatcgattgt cttcttttcc aatttatcga taatgccaaa ggtattatct
     6541 tcataaatat caaagttgat ttccggataa aacttagtta aatcttgaaa acttttcata
     6601 ggaattagtc cagttgatga tgaagccatg cctattgcaa tcgtgcctag ttcacctgaa
     6661 acagttttat gaacctgatt tttcacgctt tctgataaag agagaatttc actagcatag
     6721 ctctgcaaaa tttgtccagc atctgttaat tcaattccat gagcagtacg cttaaataat
     6781 tgtgctccta gttctatttc tagttgcttt aattgataac tcagcggcgg ttgtgcaatg
     6841 tatagtcttt tagctgctga agtgatttgc ttttctttgg ctactactaa aaagtagcgt
     6901 aattgtttaa tattcattaa taatctatct tttttatttt agttgtatct cttattaaaa
     6961 atttctatat cttatatttt aatttagtat tttcattcaa acaacatatg tgctacttta
     7021 ttaaggtaga tttggaggga ataaaatgtc tgaaaaattt catggcttaa ctcaagccga
     7081 agcagataag agacttaagg aagatgggtt aaacgaagca cctgaacccg aatacaactt
     7141 ttttaaggaa tttctatcaa aattatggaa tctttctgcc tgggttctag aaggtgcctt
     7201 aatcctcgaa tgtatcttag gcaaatggat tcaatctttg ttcgtcttgt tgatgcttct
     7261 ttttgcggct tttaacggtg catccaagaa gaaacagtca cggcgggtat taaataccat
     7321 ttcacataag ctaaccccta aggtggctgt agaacgcgat ggtaagtgga tcaaaattga
     7381 ctctaagcaa ttagttagag gcgacttaat ctcacttcaa cgtggagatg tacttgcagc
     7441 cgatgtaaaa atggttagcg gtaagatcgc ctgtgatgaa agctcaatta ccggtgaatc
     7501 taagcccgtt aaaaagaaca ttgatgacac agcttatgct ggtactactg ttgttgaagg
     7561 cgatggatta gcaattgtta ctgcaactgg taaagattca agaagtggta agaccattaa
     7621 cttgatcaac aattcagctg cacctggtca cttgcaacaa cttttaacta agattattta
     7681 ctacctttgc ctacttgacg gtgtacttac cttagttatt atcattgctt cattctttaa
     7741 gggtggtaat tttgatacgt ttatcaacat gttgccattc ttagccatga tgttcatcgc
     7801 ttcaattccg gttgcgatgc cgtcaacctt tgcattgtcc aattcatttg aagcaacccg
     7861 tttaagtaaa gaaggcgtct taacagctga tttaactggt atccaagatg cagctaactt
     7921 aaacttgctt ttacttgata agacgggaac aatcactgaa aacaaaactg cagttgctag
     7981 ttggagcaat ttaagcgatt tgccagataa agatgtactt gctttagtcg gtagtgcaac
     8041 tgataagcgc aatgcaggta tcattgatat cgccattgat gaatacttaa aagaaaacga
     8101 tatccctgtc atggacgttg aacactttac cccatttact tctgacactg gctattctat
     8161 ggctgaagta gatggtcaca atgttaagtt aggttcattt aagcaacttt cattaatcga
     8221 taagaatgca aatgaagcag ttgaaggcat caattttaaa gctggacgct cagttgccgt
     8281 gttaattgat gacaaacttg cgggagtatt tatcttacaa gataaagtaa gaaaggactc
     8341 taaggctgct ttagcagaac ttaaaaaacg gggcgtacgt ccaatcatgt taactggtga
     8401 taatcaaaga actgccgcag cagtcgctga acaagttgat ttaactggta acgttatctc
     8461 tattcatgac tttgatgaaa gcaccgatat tgatgaatta gcaggaattg ccgatgtttt
     8521 acctgaagat aaacttaaga tggttaaatt cttccaagaa aaaggttata tcgttggtat
     8581 gactggtgat ggtgttaacg actctcctgc tttaaagcaa gctgaagttg gtattgctgt
     8641 ttctaacgct gccgatgttg ccaagcgttc aagtaagatg gtgcttctag atgatggctt
     8701 aagctctatt gttaaaattc ttgatgctgg tcaccgtgta tatcaacgaa tgactacttg
     8761 gtcacttgct aagctcgcca gaaccgccga attaactatg cttttaacct tcggctatct
     8821 cttcttcaac tatattccaa tggcattaaa tgctatggtt atttacacaa tcatgaataa
     8881 catggttacc atgatgattg gtaccgaccg tacccatatt acttacaaac cagaaaattg
     8941 gaatatggca aggttagcca aaatcgcatt ctctcttgct gcaggttgga cagttatcgg
     9001 tatcgctttt ttcagctacc tcaacatgca tggctggagt cacaattcta tctctaccat
     9061 ggtctatgtt tacttagttc taagtgcaat gttaattgta ttaattacta gaactcgtaa
     9121 atacttctgg caagattatc catctaaact tgtaggtatt gttcaaattg ccgatgtcgc
     9181 attaaccttt attttagctt tatgcggttt agcaatggct caaattagtt ggcaaaactt
     9241 attaattacc gttgtggttg cattaattgc agcaattatt attgatttga tttatcaacc
     9301 agtaatgaaa aacagataat taacttaaaa caaaaacact ctgaaaacta aattactaca
     9361 atgtagtttt cagagtgttt tttttgatta ataattagta actgtagtca aggcattcaa
     9421 agccttaaca tattcaccat cagcaatttt gataaatggt ttttcattaa tttctttatg
     9481 gcctaaatag ttaaccttag caccacgctt taaaaatttg cctgggattt tttcaccatt
     9541 ctcatcataa acaaaggaat gctttttgat tctattaact acttttacag tagtcttcat
     9601 atatggcaag aaggcttctt ccttaacaaa tctattttta cgaatcttta cataagtatt
     9661 accattaatt acttttatgg cacgtacttt gtaaagcttt ccctttctta aatgtccaac
     9721 tttaacacca tgtctattat aaacagtagc atttctagtt agatttaatc tcttaccttg
     9781 tctaactgga ttagtaacaa ctgcatcaac gctttgtgta gttgctgcgc ctaatccaat
     9841 aactgctaac attatacctg cagcagaaat aatttgtttt ctcatcataa tccacccccg
     9901 tagtgtttat accattctcc atcccttatt ttatcaaaaa ttatcgaatt ggaagcattt
     9961 tttactcatc tgttttataa ctatttgctt aattctgcta aaattattta taacactact
    10021 taattcatga ttttaacttg ggatataatc cgtaggacta tcgaagtctt atggattatc
    10081 aatattgcgt ttgctgtatg gacggtcttt agaagtcgcc gcagcgttgt tgcaacttgg
    10141 gcatagatgc ttgtattaac cgttctgccc ggtatcggtt ttatcctata tcttttcttt
    10201 ggtcgtcagc tttcacatga tgaaatcttt gctattcaag aagagcaaaa aaaggtacaa
    10261 agacattatt tagctgagca acgcgacatg cttaaagagc acgatcttct acctgaaaaa
    10321 gagcgtcttc cacgagtaag aatgctttcg gaactaaatc ttaacaacga tgatgcgatt
    10381 ttaacttttg ataatcaggt caaagtattt atttctggac cagaactttt tgaccaaatg
    10441 attactgata tcaaaaatgc caaaaaatct gtcagcttag aattatatac tttttattct
    10501 aaccaattag ggcatcgtgt tttaaaagcc ttggaagagg ctgcagctaa tggtgctaag
    10561 gtaagagtaa tttatgatac ctctggatca agaggcacta agccaagctt ttttgaccat
    10621 ttaagggcgg cgaagctcag ccatttattt ccacttcaaa aaagcactgg tttactaccc
    10681 cacgactcaa ttaccactta catagaaaat tagttattat tgaccaccat attggctata
    10741 ttggcggatt taatattgga gatcaatatg tcaataaatc accaaaattc ggtcattggc
    10801 gggataccca tttacgtgta attgggcaat caccaattct aatggaggtc cggtttgcaa
    10861 tggactggaa cacgtcaatc agaagaacaa atttacctaa atttgaatta aaggaactta
    10921 aaccatttac tgtcaatcga aaagatatca atgataataa aaatgtcgct atgcaaattg
    10981 tttcctcagg acctgataat caacattacg gcatcagacg aggctgaggg aattattgca
    11041 ggagctaaaa aatacattta tattcaaacg ccttatttaa ttcccgaaga atcaattctt
    11101 gaagccttaa ttatcgctgc taacagcggt attgatgttc gaattatggt tccttgcatg
    11161 cccgatcatc catttgttta tcgtgctaca gaatactatg ctaagtattt agtagcccat
    11221 ggcgttaaag tatacaaata taatgatggt tttattcatg caaaaactat ggttagcggt
    11281 tctaatattt cttcagttgg ttccgccaat caagatttcc gaagctatac attaaacttt
    11341 gaggtaaact cattcaacta caaccctgct ttaactcaag aattaaagaa aatttttgag
    11401 aaggacttag ataaatgtac ccttttaact aatgactact ttgctcaaca atcatcatgg
    11461 ttaaaattta agcaatactt ctcaagatta ttatcaccta ttttttaatg aaaagccctc
    11521 tatcggtcta tccgatgggg gttttacttt gtattttaaa aatgcagttt tatttcttta
    11581 cttatttttt ataagttata taataatgat aactattaaa aagtaaggag gataaaactt
    11641 ggctaataga gtaaaaatag gcgttttgaa tttaatgcac gataagttag atactcaaca
    11701 aagatttgca cgcgttttgc cagatgcaga cctgactttc ttttatccac gtatgcatta
    11761 tcaaaatcgt cctgtcccac ctgaagttgc aaaaacttcc cagccattag atcttaatca
    11821 aatcaaagag tttgatggct ttatcattac gggcgcacct ttagatcatc ttgattttga
    11881 tcaagttacc tacatcgagg aagtccgatg tttgctccaa ctattagata aatacaagtt
    11941 gcagcaatta tatttttgct ggggtgcaat ggccgcttta gattattttt acaatattca
    12001 aaaaagaatt ttatcgaaaa aaatctttgg tgtttttcct catttaatta tcgaaccaca
    12061 tcctttatta aatggactca gcaaaggatt tatcgctcca catgctcgtt acgctgaaat
    12121 ggataaaaca cagattatgc aagatccacg attaaccatt aattcagttg acgataatgg
    12181 gcatctattt atggtctctt ctttagaaaa gcctgagcaa aattttattt tctctcatat
    12241 cgaatatggc cgaaaaggcc ttaaaaaaga atatgaaaga gagattgctg cacatccaga
    12301 gcgacattat aagaagccag aaaattattc attatcaaat ctattgtttc aatggaaaga
    12361 tactcagaaa acatttttca ataactggct aactcaagtt aaaaaaagca aattagtatt
    12421 attagataaa taaaacgagg catacattat gtctacaatt tataattcag ttacagaact
    12481 tatcggcaac actccattac ttaagttgaa tcgcgttgta cctgacgacg cggcagatgt
    12541 ctatgtaaag ttagaatttg aaaacccagc tggttcaatt aaagacagaa ttgctttagc
    12601 tatgatcgaa aaagctgaac gtgaaggcaa cctaaagcca ggtggcacaa ttgtagaacc
    12661 tacttcaggc aataccggta tcggtttagc catggttgct gcagctaagg actatcacat
    12721 tattattgtt atgccagaaa ctatgagcgt tgagcggcgt aaattaatga agggctatgg
    12781 tgctgaactt attttgacac caggtgcaga cggtatgaag ggttcaattg ctaaggccga
    12841 agaattagtt aaagagaaag gctacttcat gccaatgcaa tttgaaaata cagaaaatcc
    12901 taatattcat gaattaacta ctggtccaga aattattgcc gcaatgaatg gtatcggcaa
    12961 atccgttgat gcctttgttg ctggtgttgg tactggtggt actttatcag gaattggaca
    13021 tgcacttagg cgtgaaaatc catccactaa gatatttgca cttgagccaa ctgaatctcc
    13081 actcttaaaa gatggaaaaa caggtaaaca tggtatccaa ggtattgccg caggtttcat
    13141 ccctaagaat ttagataagg atatctacga tgatataatt acagtttcta ctgatgaagc
    13201 aatggctaca gctcgtgaag tagctaaaaa cgaaggcttc ttacctggta tttcagctgg
    13261 tgcaaacatc catggtgcaa tcgaaattgc taaaaagtta ggcaagggac atgctgtggt
    13321 tactgtagtt ccagacggcg gtgatcgtta cctttcaact gcattattta atgcttaaaa
    13381 cttaatttct gtaaacaaat actcctaagt aaaatttcct taggagtatt atttttattt
    13441 ctgttgattg tgcaccagtc aatgttggta caacactttt agtataatga cctttactaa
    13501 ttagatcaat attgaattta tttaagcacc atgatattgc actaagctgt aaatatcaac
    13561 atcaggcaac ttttctctac cctttaaatc aggcaattca atgtaaaatg cagcacctac
    13621 aagcttacca ccaagatttt caattaattc cttagaagct cttaaagtac ctgcagtagc
    13681 cattaaatcg tcacagagaa caactctttg gccaggctta attgcatctt tatgcatttc
    13741 aaggctattt gaaccgtatt ccaagtcata tgaagcacgt tcaacttctc ttggcaactt
    13801 atgtggcttt cttgctggaa caaaacctaa gcctaactca gttgcaacag gacagcctac
    13861 aataaagcca cgtgcttcag gacctacgat tacatctgcc tttctactct ttgcatattc
    13921 tgccaattca tgagtagcaa tacgatacaa ttcaccatct tgcaaaatag gtgtaatatc
    13981 gcgaaagaca attcccttat taggaaagtc cttaacactt gcaatatatt tactaaaatc
    14041 aatcgccata agaagaaaaa cctccataat tctgtgcgtt tgtattcaaa cacttttgac
    14101 ttgtatattt taccaaagat ttgttataaa agtactgaaa tcttgatatt tatctatctt
    14161 tttaccaaat tattaacata tgtaattaat ttttgagtag gcatcgttct tagttgatta
    14221 ataaatttaa tttgtgaact cgttgccatt aaatatttag aagctgtcaa tggttgcttc
    14281 tttggattag actcaccaac taatttttga tcgtctaatt taacaaaacc taattcaaag
    14341 aatactcgca aaataaacaa tacactatca taatccaaac ctagatatgg tgctacagtg
    14401 cgatagtctt caggctttaa tgctggatgg gcataaatat actttaacac ttttccgaaa
    14461 taactctttg ctggaatttg ttcaacaggt aactgatcta ataaaaagca taaataaatt
    14521 tgttgataat ctttttttaa agctgcattt aattccactt gattgcgagg cacatcaagc
    14581 aaagctactg tttcacccga ttgatcataa tctttaacca agctaatttt atcatcatca
    14641 atttgaaggc tattcttaac aattggaata ttctttttgt caaaaagcaa ataacgatct
    14701 gcaaggccca tgacaaattt ctcttgtctt aaatcaatta ctgatgttgg cacagctaat
    14761 tttggggatg caaaggctat tccttccatg atgccttgca aagatacttg tttgcgataa
    14821 gtattcaaag agagagtaac aaagattttt gaaataaatg gtaacaaatt attattcaaa
    14881 taatccttat taaatcccac aattgctaaa ttgccgtctt ttttattagc tattaattta
    14941 acatgattct tatcttttcc tattttgaaa aagtgtgtaa tagttggatc cgaaatacta
    15001 aaaattggct gcggatcacc agtaccaaat ggtcccactt gattaatttg agccaaagtt
    15061 tgaggtgata agtcatgcat aggcaattcc atatcgtact ctttagtctc taaaccaccg
    15121 tcaacatgaa aatcggcttc aaacttttcc cgtaggtcat ttactttatc ttcttccatg
    15181 gataaaccac aagcaaaatc atgacctcca aatttggtca atagactttc ttttaacgga
    15241 ttaagagcat caaataagtt aaaaccactg agtgaacgac ctgatccctt aatctcccct
    15301 tcatcgtttt tagttaaaac aattgttggt ttatgcagtt tttccactat cttgttagca
    15361 acaagcccca aaactccttc atgaaaatca ggatcatata aaactaaagt attttgcttt
    15421 tgccaactat tttcacgaac taattccatg cagcgatcgt aaacctcagt agttagctct
    15481 ttacgcttat tatttaagtc ttcaatctga tctgcgatct tctgtgcctc aagatcatca
    15541 tcactaagca aaagctctac tgccagatta gcattagcca aacgtccaac agcattaagt
    15601 ctaggagcaa tattaaagcc tacatctgtc tcattaatcg tttctagcgt taaaccggca
    15661 tttttgataa gcgctcttaa gcccggtcgt tcggtttgat taagaacatc taacccacgt
    15721 tttacaataa tatggccttc accagtaact ttaaccatgt caccaatagt accgatcatt
    15781 gctaaatcta gcaattctgg tacaggatcc tgcataagct cacgacaaat tgtataagct
    15841 acacctgcac cacaataatc atcaaaagga tattcttgac caggataatt acagtgaaca
    15901 attgcataag catctggctt attttcttga aaagtatggt gatccgtaat aatagtatca
    15961 acgccatgtt ctttagcgta ttcaacttct
//
